3,642 research outputs found
Meningite CrĂ´nica, Hidrocefalia E Paraplegia Medular Em Histoplasmose NĂŁo-sistĂŞmica
7451451
Meningite CrĂ´nica, Hidrocefalia E Paraplegia Medular Em Histoplasmose NĂŁo-sistĂŞmica
74651451
Meningite crĂ´nica, hidrocefalia e paraplegia medular em histoplasmose nĂŁo-sistĂŞmica
[No abstract available]sem informação746514515sem informaçãosem informaçã
Antibody response against plasmid-encoded toxin (Pet) and the protein involved in intestinal colonization (Pic) in children with diarrhea produced by enteroaggregative Escherichia coli
Enteroaggregative Escherichia eoli (EAEC) is an emerging cause of pediatric and adult travellers diarrhea. the mechanism by which EAEC induce diarrhea is not completely known. Two serine protease autotransporter proteins, named Pet and Pic have been identified in EAEC strains. Pet has enterotoxic and cytotoxic activities, while the role of Pic in pathogenesis may lie on its mucinolytic activity. Little is known about Pet and Pic biological activities in vivo. in this study the antibody responses against these autotransporter proteins in convalescent children is investigated. Fifteen (83%) children showed specific antibodies against Pet or Pic in their sera. IgG and IgM antibodies were the main isotype found. Specific antibodies against Pic, but not against Pet, were detected in sera from age-matched control group. These data show that specific anti-Pet and anti-Pic antibodies are produced during the course of a natural EAEC infection in children. (C) 2004 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.Univ SĂŁo Paulo, Dept Microbiol, Inst Ciencias Biomed, SĂŁo Paulo, BrazilInst Butantan, Lab Especial Microbiol, SĂŁo Paulo, BrazilUniversidade Federal de SĂŁo Paulo, Dept Microbiol Imunol & Parasitol, SĂŁo Paulo, BrazilUniv SĂŁo Paulo, Fac Ciencias Farmaceut, Dept Anal Clin & Toxicol, BR-05508900 SĂŁo Paulo, BrazilCINVESTAV, IPN, Dept Cell Biol, Mexico City 14000, DF, MexicoUniversidade Federal de SĂŁo Paulo, Dept Microbiol Imunol & Parasitol, SĂŁo Paulo, BrazilWeb of Scienc
Comparaçþes ambientais de Bothrops atrox na Amazônia Oriental.
A regiĂŁo de SantarĂŠm (PA) estĂĄ relacionada com 92% dos acidentes ofĂdicos, dos quais 20% foram considerados graves. AtravĂŠs do uso da metodologia dos isĂłtopos estĂĄveis do carbono-13 (13C) e do nitrogĂŞnio-15 (15N), pretende-se verificar se as variaçþes dos hĂĄbitos e fontes alimentares existentes nos diferentes ambientes e usos de solo na AmazĂ´nia, neste caso ĂĄreas de floresta, savana e pastagem, influenciam na composição isotĂłpica das serpentes encontradas nestes ambientes, de forma a auxiliar estudos de correlação, com a variabilidade de seus venenos. As serpentes, assim como as suas possĂveis presas, foram coletadas nos trĂŞs ambientes, atravĂŠs de trĂŞs mĂŠtodos de coleta ? encontro ocasional, busca ativa e armadilhas de interceptação e queda ? e tiveram os seus tecidos analisados isotopicamente. Ainda serĂŁo realizadas mais coletas de serpentes e de suas fontes alimentares e essas amostras dos diferentes ambientes tambĂŠm serĂŁo analisadas isotopicamente. SupĂľe-se que as diferentes fontes alimentares nos diferentes ambientes serĂŁo isotopicamente distintas, com reflexo na composição isotĂłpica dos tecidos das serpentes. Caso se confirme tais hipĂłteses este estudo contribuirĂĄ para o conhecimento da ecologia da serpente e seu uso dos ambientes, ainda pouco relatados, como para o aprimoramento futuro dos soros antiofĂdicos e diminuição das seqĂźelas geradas pelos acidentes
Intensification of cattle ranching production systems: Socioeconomic and environmental synergies and risks in Brazil
Intensification of Brazilian cattle ranching systems has attracted both national and international attention due to its direct relation with Amazon deforestation on the one hand and increasing demand of the global population for meat on the other. Since Brazilian cattle ranching is predominantly pasture-based, we particularly focus on pasture management. We summarize the most recurrent opportunities and risks associated with pasture intensification that are brought up within scientific and political dialogues, and discuss them within the Brazilian context. We argue that sustainable intensification of pasturelands in Brazil is a viable way to increase agricultural output while simultaneously sparing land for nature. Since environmental degradation is often associated with low-yield extensive systems in Brazil, it is possible to obtain higher yields, while reversing degradation, by adopting practices like rotational grazing, incorporation of legumes and integrated crop-livestock-forestry systems. Technical assistance is however essential, particularly for small- and medium-scale farmers. Sound complementary policies and good governance must accompany these measures so that a ârebound effectâ does not lead to increased deforestation and other adverse social and environmental impacts. It is also important that animal welfare is not compromised. Although the discussion is presented with respect to Brazil, some aspects are relevant to other developing countries
The step of incorporation of Bacillus coagulans GBI-30 6086 into ârequeijĂŁo cremosoâ processed cheese does not affect metabolic homeostasis of rats
Dairy product consumption is a common habit in Brazil. These products present a good matrix for probiotic incorporation. Thus, in this study the feasibility of producing a probiotic "requeijao cremoso" incorporated with Bacillus coagulans GBI-30 6086 in three different steps and its metabolic effect in an animal model for 2 weeks has been evaluated. Wistar adult health rats were randomized into one to five groups (n = 8 for each group): Control (C); "requeijao cremoso" without probiotic (RC); probiotic inoculated in the milk before pasteurization at 65 degrees C/30 min (RPP); "requeijao cremoso" inoculated before the fusion step and consequently exposed to 90 degrees C/5 min (RPF); and "requeijao cremoso" inoculated after fusion step, i.e., once the product temperature reached 50 degrees C (RPAF). At the end of treatment, analysis of molecular markers of proteins of stress and antioxidant system, HSP 25, 60, 70 and 90, SOD and catalase were performed in the animals' muscles by Western Blot technique. The HSP25, HSP90 and catalase levels of C, RPP, RPF, and RPAF were similar, indicating that the homeostasis remained unchanged. The incorporation of B. coagulans GBI-30 6086 in the "requeijao cremoso" was shown to be stable and the microorganism remained viable in all steps tested. The incorporation of the probiotic strain in the fusion stage facilitated the technological process, since it allowed a better homogenization of the product and did not affect the maintenance of the metabolic homeostasis of rats10CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTĂFICO E TECNOLĂGICO - CNPQCOORDENAĂĂO DE APERFEIĂOAMENTO DE PESSOAL DE NĂVEL SUPERIOR - CAPESFUNDAĂĂO DE AMPARO Ă PESQUISA DO ESTADO DE SĂO PAULO - FAPESPsem informação302763/2014-7; 305804/2017-013/21544-9; 18/24540-8; 2019/21188-
Highlights from the Pierre Auger Observatory
The Pierre Auger Observatory is the world's largest cosmic ray observatory.
Our current exposure reaches nearly 40,000 km str and provides us with an
unprecedented quality data set. The performance and stability of the detectors
and their enhancements are described. Data analyses have led to a number of
major breakthroughs. Among these we discuss the energy spectrum and the
searches for large-scale anisotropies. We present analyses of our X
data and show how it can be interpreted in terms of mass composition. We also
describe some new analyses that extract mass sensitive parameters from the 100%
duty cycle SD data. A coherent interpretation of all these recent results opens
new directions. The consequences regarding the cosmic ray composition and the
properties of UHECR sources are briefly discussed.Comment: 9 pages, 12 figures, talk given at the 33rd International Cosmic Ray
Conference, Rio de Janeiro 201
The Pierre Auger Observatory III: Other Astrophysical Observations
Astrophysical observations of ultra-high-energy cosmic rays with the Pierre
Auger ObservatoryComment: Contributions to the 32nd International Cosmic Ray Conference,
Beijing, China, August 201
Combined search for the quarks of a sequential fourth generation
Results are presented from a search for a fourth generation of quarks
produced singly or in pairs in a data set corresponding to an integrated
luminosity of 5 inverse femtobarns recorded by the CMS experiment at the LHC in
2011. A novel strategy has been developed for a combined search for quarks of
the up and down type in decay channels with at least one isolated muon or
electron. Limits on the mass of the fourth-generation quarks and the relevant
Cabibbo-Kobayashi-Maskawa matrix elements are derived in the context of a
simple extension of the standard model with a sequential fourth generation of
fermions. The existence of mass-degenerate fourth-generation quarks with masses
below 685 GeV is excluded at 95% confidence level for minimal off-diagonal
mixing between the third- and the fourth-generation quarks. With a mass
difference of 25 GeV between the quark masses, the obtained limit on the masses
of the fourth-generation quarks shifts by about +/- 20 GeV. These results
significantly reduce the allowed parameter space for a fourth generation of
fermions.Comment: Replaced with published version. Added journal reference and DO
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