304 research outputs found

    Solid angle subtended by a cylindrical detector at a point source in terms of elliptic integrals

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    The solid angle subtended by a right circular cylinder at a point source located at an arbitrary position generally consists of a sum of two terms: that defined by the cylindrical surface (Ωcyl\Omega_{cyl}) and the other by either of the end circles (Ωcirc\Omega_{circ}). We derive an expression for Ωcyl\Omega_{cyl} in terms of elliptic integrals of the first and third kinds and give similar expressions for Ωcirc\Omega_{circ} using integrals of the first and second kinds. These latter can be used alternatively to an expression also in terms of elliptic integrals, due to Philip A. Macklin and included as a footnote in Masket (Rev. Sci. Instr., 28 (3), 191-197, 1957). The solid angle subtended by the whole cylinder when the source is located at an arbitrary location can then be calculated using elliptic integrals.Comment: 10 pages, 3 figures, LaTex. Typos corrected. References added. Accepted in Rad. Phys. Che

    Analytical calculation of the solid angle defined by a cylindrical detector and a point cosine source with orthogonal axes

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    We derive analytical expressions for the solid angle subtended by a right circular cylinder at a point source with cosine angular distribution in the case where the source and the cylinder axes are mutually orthogonal.Comment: 19 pages, 13 figures, Latex. Typos corrected. Accepted in Rad. Phys. Che

    Thermocline management of stratified tanks for heat storage

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    Stratified tanks are useful for maximising the thermal energy efficiency of non-continuous and semi-continuous processes. Liquid at two or more dissimilar temperatures is stored within the same tank to provide a buffer for variations in heating and cooling loads. Control of the thermocline between the hot and cold fluid regions is needed to minimise thermocline growth and maximise operation of the storage tank. An experimental programme using a scale model of an industrial stratified tank (aspect ratio 3.5) and Perspex tank (aspect ratio 8.2) is reported. The behaviour and growth of the hot-cold thermocline under various operating conditions is presented. A siphoning method to re-establish the thermocline without interrupting the use of the tank is tested. Siphoning of the thermocline region from either 20%, 50% or 80% of the tank height is an effective strategy for uninterrupted interface re-establishment. However, the rate and position of siphoning and the load balance of the exit streams are critical variables for minimising the time for effective re-establishment of the two temperature zones

    Towards Probabilistic Model Checking on P Systems Using PRISM

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    This paper presents the use of P systems and π-calculus to model interacting molecular entities and how they are translated into a probabilistic and symbolic model checker called PRISM.Ministerio de Educación y Ciencia TIN2005-09345-C04-01Junta de Andalucía TIC-58

    Epidemics in Adaptive Social Networks with Temporary Link Deactivation

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    Disease spread in a society depends on the topology of the network of social contacts. Moreover, individuals may respond to the epidemic by adapting their contacts to reduce the risk of infection, thus changing the network structure and affecting future disease spread. We propose an adaptation mechanism where healthy individuals may choose to temporarily deactivate their contacts with sick individuals, allowing reactivation once both individuals are healthy. We develop a mean-field description of this system and find two distinct regimes: slow network dynamics, where the adaptation mechanism simply reduces the effective number of contacts per individual, and fast network dynamics, where more efficient adaptation reduces the spread of disease by targeting dangerous connections. Analysis of the bifurcation structure is supported by numerical simulations of disease spread on an adaptive network. The system displays a single parameter-dependent stable steady state and non-monotonic dependence of connectivity on link deactivation rate

    Optimizing design of research to evaluate antibiotic stewardship interventions: consensus recommendations of a multinational working group.

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    BACKGROUND: Antimicrobial stewardship interventions and programmes aim to ensure effective treatment while minimizing antimicrobial-associated harms including resistance. Practice in this vital area is undermined by the poor quality of research addressing both what specific antimicrobial use interventions are effective and how antimicrobial use improvement strategies can be implemented into practice. In 2016 we established a working party to identify the key design features that limit translation of existing research into practice and then to make recommendations for how future studies in this field should be optimally designed. The first part of this work has been published as a systematic review. Here we present the working group's final recommendations. METHODS: An international working group for design of antimicrobial stewardship intervention evaluations was convened in response to the fourth call for leading expert network proposals by the Joint Programming Initiative on Antimicrobial Resistance (JPIAMR). The group comprised clinical and academic specialists in antimicrobial stewardship and clinical trial design from six European countries. Group members completed a structured questionnaire to establish the scope of work and key issues to develop ahead of a first face-to-face meeting that (a) identified the need for a comprehensive systematic review of study designs in the literature and (b) prioritized key areas where research design considerations restrict translation of findings into practice. The working group's initial outputs were reviewed by independent advisors and additional expertise was sought in specific clinical areas. At a second face-to-face meeting the working group developed a theoretical framework and specific recommendations to support optimal study design. These were finalized by the working group co-ordinators and agreed by all working group members. RESULTS: We propose a theoretical framework in which consideration of the intervention rationale the intervention setting, intervention features and the intervention aims inform selection and prioritization of outcome measures, whether the research sets out to determine superiority or non-inferiority of the intervention measured by its primary outcome(s), the most appropriate study design (e.g. experimental or quasi- experimental) and the detailed design features. We make 18 specific recommendation in three domains: outcomes, objectives and study design. CONCLUSIONS: Researchers, funders and practitioners will be able to draw on our recommendations to most efficiently evaluate antimicrobial stewardship interventions

    Private Narratives and Infant Views: Iconizing 1970s Militancy in Contemporary Argentine Cinema

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    This is the author's accepted manuscript, made available with the permission of the publisher.This article analyses the connections between the subjective turn in the representation of militancy, iconicity, and historical examination in Infancia clandestina, a recent Argentine film that portrays the 1970s armed struggle through a child’s lens. Breaking with the leading interpretation that praises the movie because of its original exposition of left-leaning violence, I contend that this coming-of-age story fits within a version of militancy that originated in the mid-1990s and that has become quite common since the advent of the Kirchner administration in 2003. This particular version relies on a privatized and archaic image of activism that is at the core of the global iconization of 1970s militancy. An analysis of the filmic use of an infant perspective and of anime-style cartoons illuminates how contemporary Argentine cinema both registers and participates in this iconizing process
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