Measurement of the flavour-specific CP-violating asymmetry as sl in B0s decays

The CP  -violating asymmetry is studied using semileptonic decays of and mesons produced in pp   collisions at a centre-of-mass energy of 7 TeV at the LHC, exploiting a data sample corresponding to an integrated luminosity of 1.0 fb−1. The reconstructed final states are , with the particle decaying in the ϕπ± mode. The yields are summed over and initial states, and integrated with respect to decay time. Data-driven methods are used to measure efficiency ratios. We obtain , where the first uncertainty is statistical and the second systematic

AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders.

AMPA receptors (AMPARs) are tetrameric ligand-gated channels made up of combinations of GluA1-4 subunits encoded by GRIA1-4 genes. GluA2 has an especially important role because, following post-transcriptional editing at the Q607 site, it renders heteromultimeric AMPARs Ca2+-impermeable, with a linear relationship between current and trans-membrane voltage. Here, we report heterozygous de novo GRIA2 mutations in 28 unrelated patients with intellectual disability (ID) and neurodevelopmental abnormalities including autism spectrum disorder (ASD), Rett syndrome-like features, and seizures or developmental epileptic encephalopathy (DEE). In functional expression studies, mutations lead to a decrease in agonist-evoked current mediated by mutant subunits compared to wild-type channels. When GluA2 subunits are co-expressed with GluA1, most GRIA2 mutations cause a decreased current amplitude and some also affect voltage rectification. Our results show that de-novo variants in GRIA2 can cause neurodevelopmental disorders, complementing evidence that other genetic causes of ID, ASD and DEE also disrupt glutamatergic synaptic transmission

Searches for violation of lepton flavour and baryon number in tau lepton decays at LHCb

Searches for the lepton flavour violating decay τ−→μ−μ+μ−τ−→μ−μ+μ− and the lepton flavour and baryon number violating decays sourceτ−→p¯μ+μ− and τ−→pμ−μ−τ−→pμ−μ− have been carried out using proton–proton collision data, corresponding to an integrated luminosity of 1.0 fb−11.0 fb−1, taken by the LHCb experiment at s=7 TeV. No evidence has been found for any signal, and limits have been set at 90%90% confidence level on the branching fractions: B(τ−→μ−μ+μ−)<8.0×10−8B(τ−→μ−μ+μ−)<8.0×10−8, B(τ−→p¯μ+μ−)<3.3×10−7 and B(τ−→pμ−μ−)<4.4×10−7B(τ−→pμ−μ−)<4.4×10−7. The results for the τ−→p¯μ+μ− and τ−→pμ−μ−τ−→pμ−μ− decay modes represent the first direct experimental limits on these channels

Observation of B[0s χc1φ decay and study of: B0 -> χ c1,2K*1 decays

The first observation of the decay B0s → χc1φ and a study of B0 → χc1,2K*0 decays are presented. The analysis is performed using a dataset, corresponding to an integrated luminosity of 1.0 fb-1, collected by the LHCb experiment in pp collisions at a centre-of-mass energy of 7 TeV. The following ratios of branching fractions are measured: Where the third uncertainty is due to the limited knowledge of the branching fractions of χc → J/ψγ modes. © 2013 CERN. Published by Elsevier B.V

Search for D+(s) to pi+ mu+ mu- and D+(s) to pi- mu+ mu+ decays

21 pages, 5 figures - See paper for full list of authorsA search for non-resonant D+(s) to pi+mu+mu- and D+(s) to pi-mu+mu+ decays is performed using proton-proton collision data, corresponding to an integrated luminosity of 1.0 fb-1, at sqrt(s) = 7 TeV recorded by the LHCb experiment in 2011. No signals are observed and the 90% (95%) confidence level (CL) limits on the branching fractions are B(D+ to pi+mu+mu-) < 7.3 (8.3) x 10-8, B(Ds+ to pi+mu+mu-) < 4.1 (4.8) x 10-7, B(D+ to pi-mu+mu+) < 2.2 (2.5) x 10-8, B(Ds+ to pi-mu+mu+) < 1.2 (1.4) x 10-7. These limits are the most stringent to date

Search for direct CP violation in D0 -> h- h+ modes using semileptonic B decays

15 pages, 4 figures - See paper for full list of authorsA search for direct CP violation in D0 -> h- h+ (where h=K or pi) is presented using data corresponding to an integrated luminosity of 1.0 fb^-1 collected in 2011 by LHCb in pp collisions at a centre-of-mass energy of 7 TeV. The analysis uses D0 mesons produced in inclusive semileptonic b-hadron decays to the D0 mu X final state, where the charge of the accompanying muon is used to tag the flavour of the D0 meson. The difference in the CP-violating asymmetries between the two decay channels is measured to be Delta A_CP = A_CP(K-K+) - A_CP(pi-pi+) = (0.49 +- 0.30 (stat) +- 0.14 (syst)) % . This result does not confirm the evidence for direct CP violation in the charm sector reported in other analyses

Search for the rare decay D0→μ+μ−D^0 \to \mu^+ \mu^-

22 pages, 8 figures, Submitted to Physics Letters BA search for the rare decay $D^0 \to \mu^+ \mu^-$is performed using a data sample, corresponding to an integrated luminosity of 0.9 fb$^{-1}$, of $pp$ collisions collected at a centre-of-mass energy of 7 TeV by the LHCb experiment. The observed number of events is consistent with the background expectations and corresponds to an upper limit of \mbox{${\cal B}(D^0 \to \mu^+ \mu^-) < 6.2(7.6) \times 10^{-9}$} at \mbox{90%} \mbox{(95%)} confidence level. This result represents an improvement of more than a factor twenty with respect to previous measurements