The Sloan Digital Sky Survey Reverberation Mapping Project: Rapid CIV Broad Absorption Line Variability

We report the discovery of rapid variations of a high-velocity CIV broad absorption line trough in the quasar SDSS J141007.74+541203.3. This object was intensively observed in 2014 as a part of the Sloan Digital Sky Survey Reverberation Mapping Project, during which 32 epochs of spectroscopy were obtained with the Baryon Oscillation Spectroscopic Survey spectrograph. We observe significant (>4sigma) variability in the equivalent width of the broad (~4000 km/s wide) CIV trough on rest-frame timescales as short as 1.20 days (~29 hours), the shortest broad absorption line variability timescale yet reported. The equivalent width varied by ~10% on these short timescales, and by about a factor of two over the duration of the campaign. We evaluate several potential causes of the variability, concluding that the most likely cause is a rapid response to changes in the incident ionizing continuum. If the outflow is at a radius where the recombination rate is higher than the ionization rate, the timescale of variability places a lower limit on the density of the absorbing gas of n_e > 3.9 x 10^5 cm^-3. The broad absorption line variability characteristics of this quasar are consistent with those observed in previous studies of quasars, indicating that such short-term variability may in fact be common and thus can be used to learn about outflow characteristics and contributions to quasar/host-galaxy feedback scenarios.Comment: 15 pages, 14 figures. Accepted for publication in the Astrophysical Journa

Cryptic Variation between Species and the Basis of Hybrid Performance

Studies on natural variation in gene expression and its phenotypic effects provide fresh insights into the origins of vigour and sterility in species hybrids

Supernova 2002bo: inadequacy of the single parameter description

We present optical/near-infrared photometry and spectra of the type Ia SN 2002bo spanning epochs from -13 days before maximum B-band light to +102 days after. The pre-maximum optical coverage is particularly complete. In some respects, SN 2002bo behaves as a typical "Branch normal" type Ia supernova (SN Ia) at optical and IR wavelengths. We find a B-band risetime of 17.9+-0.5 days, a Dm_{15}(B) of 1.13+-0.05, and a M_B=-19.41+-0.42. However, comparison with other type Ia supernovae having similar Delta m_{15}(B) values indicates that in other respects SN 2002bo is unusual. While the optical spectra of SN 2002bo are very similar to those of SN 1984A, lower velocities and a generally more structured appearance are found in SNe 1990N, 1994D and 1998bu. For supernovae having Dm_(15)(B) > 1.2, we confirm the variation of R(SiII) (Nugent et al. 1995) with Dm_(15)(B). However, for supernovae such as SN2002bo, with lower values of Dm_(15)(B) the relation breaks down. Moreover, the evolution of R(SiII) for SN 2002bo is strikingly different from that shown by other type Ia supernovae. The velocities of SN 2002bo and 1984A derived from SII 5640A, SiII 6355A and CaII H&K lines are either much higher and/or evolve differently from those seen in other normal SNe Ia events. We suggest that the unusually low temperature, the presence of high-velocity intermediate-mass elements and the low abundance of carbon at early times indicates that burning to Si penetrated to much higher layers than in more normal type Ia supernovae. This may be indicative of a delayed-detonation explosion.Comment: Accepted to MNRAS. Some near-IR photometry has been added. The paper can be retrieved also at http://web.pd.astro.it/supern/ps/sn02bo_v17_mn2.ps.g

Anomalous extinction behaviour towards the Type Ia SN 2003cg

We present optical and near-infrared photometry and spectroscopy of the Type Ia SN 2003cg, which exploded in the nearby galaxy NGC 3169. The observations cover a period between -8.5 and +414 days post-maximum. SN 2003cg is a normal but highly-reddened Type Ia event. Its B magnitude at maximum B_max = 15.94+/-0.04 and Delta m_15(B)_obs = 1.12+/-0.04 (Delta m_15(B)_intrinsic = 1.25+/-0.05). Allowing R_v to become a free parameter within the Cardelli et al. (1989) extinction law, simultaneous matches to a range of colour curves of normal SNe Ia yielded E(B-V) = 1.33+/-0.11, and R_v = 1.80+/-0.19. While the value obtained for R_v is small, such values have been invoked in the past, and may imply a grain size which is small compared with the average value for the local ISM.Comment: 28 pages, 21 figures. Accepted for publication in MNRAS. Minor changes following the referee suggestion

Matter-wave Atomic Gradiometer Interferometric Sensor (MAGIS-100)

MAGIS-100 is a next-generation quantum sensor under construction at Fermilab that aims to explore fundamental physics with atom interferometry over a 100-meter baseline. This novel detector will search for ultralight dark matter, test quantum mechanics in new regimes, and serve as a technology pathfinder for future gravitational wave detectors in a previously unexplored frequency band. It combines techniques demonstrated in state-of-the-art 10-meter-scale atom interferometers with the latest technological advances of the world's best atomic clocks. MAGIS-100 will provide a development platform for a future kilometer-scale detector that would be sufficiently sensitive to detect gravitational waves from known sources. Here we present the science case for the MAGIS concept, review the operating principles of the detector, describe the instrument design, and study the detector systematics.Comment: 65 pages, 18 figure

The IMPROVE guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments)

Most in vivo models of ischaemic stroke target the middle cerebral artery and a spectrum of stroke severities, from mild to substantial, can be achieved. This review describes opportunities to improve the in vivo modelling of ischaemic stroke and animal welfare. It provides a number of recommendations to minimise the level of severity in the most common rodent models of middle cerebral artery occlusion, while sustaining or improving the scientific outcomes. The recommendations cover basic requirements pre-surgery, selecting the most appropriate anaesthetic and analgesic regimen, as well as intraoperative and post-operative care. The aim is to provide support for researchers and animal care staff to refine their procedures and practices, and implement small incremental changes to improve the welfare of the animals used and to answer the scientific question under investigation. All recommendations are recapitulated in a summary poster (see supplementary information)

The VLT-FLAMES Tarantula Survey

Context. The Tarantula region in the Large Magellanic Cloud (LMC) contains the richest population of spatially resolved massive O-type stars known so far. This unmatched sample offers an opportunity to test models describing their main-sequence evolution and mass-loss properties. Aims. Using ground-based optical spectroscopy obtained in the framework of the VLT-FLAMES Tarantula Survey (VFTS), we aim to determine stellar, photospheric and wind properties of 72 presumably single O-type giants, bright giants and supergiants and to confront them with predictions of stellar evolution and of line-driven mass-loss theories. Methods. We apply an automated method for quantitative spectroscopic analysis of O stars combining the non-LTE stellar atmosphere model fastwind with the genetic fitting algorithm pikaia to determine the following stellar properties: effective temperature, surface gravity, mass-loss rate, helium abundance, and projected rotational velocity. The latter has been constrained without taking into account the contribution from macro-turbulent motions to the line broadening. Results. We present empirical effective temperature versus spectral subtype calibrations at LMC-metallicity for giants and supergiants. The calibration for giants shows a +1kK offset compared to similar Galactic calibrations; a shift of the same magnitude has been reported for dwarfs. The supergiant calibrations, though only based on a handful of stars, do not seem to indicate such an offset. The presence of a strong upturn at spectral type O3 and earlier can also not be confirmed by our data. In the spectroscopic and classical Hertzsprung-Russell diagrams, our sample O stars are found to occupy the region predicted to be the core hydrogen-burning phase by state-of-the-art models. For stars initially more massive than approximately 60 M⊙, the giant phase already appears relatively early on in the evolution; the supergiant phase develops later. Bright giants, however, are not systematically positioned between giants and supergiants at Minit ≳ 25 M⊙. At masses below 60 M⊙, the dwarf phase clearly precedes the giant and supergiant phases; however this behavior seems to break down at Minit ≲ 18 M⊙. Here, stars classified as late O III and II stars occupy the region where O9.5-9.7 V stars are expected, but where few such late O V stars are actually seen. Though we can not exclude that these stars represent a physically distinct group, this behavior may reflect an intricacy in the luminosity classification at late O spectral subtype. Indeed, on the basis of a secondary classification criterion, the relative strength of Si iv to He i absorption lines, these stars would have been assigned a luminosity class IV or V. Except for five stars, the helium abundance of our sample stars is in agreement with the initial LMC composition. This outcome is independent of their projected spin rates. The aforementioned five stars present moderate projected rotational velocities (i.e., νesini < 200kms-1) and hence do not agree with current predictions of rotational mixing in main-sequence stars. They may potentially reveal other physics not included in the models such as binary-interaction effects. Adopting theoretical results for the wind velocity law, we find modified wind momenta for LMC stars that are ~0.3 dex higher than earlier results. For stars brighter than 105 L⊙, that is, in the regime of strong stellar winds, the measured (unclumped) mass-loss rates could be considered to be in agreement with line-driven wind predictions if the clump volume filling factors were fV ~ 1/8 to 1/6

Roadmap on Photovoltaic Absorber Materials for Sustainable Energy Conversion

Photovoltaics (PVs) are a critical technology for curbing growing levels of anthropogenic greenhouse gas emissions, and meeting increases in future demand for low-carbon electricity. In order to fulfil ambitions for net-zero carbon dioxide equivalent (CO2eq) emissions worldwide, the global cumulative capacity of solar PVs must increase by an order of magnitude from 0.9 TWp in 2021 to 8.5 TWp by 2050 according to the International Renewable Energy Agency, which is considered to be a highly conservative estimate. In 2020, the Henry Royce Institute brought together the UK PV community to discuss the critical technological and infrastructure challenges that need to be overcome to address the vast challenges in accelerating PV deployment. Herein, we examine the key developments in the global community, especially the progress made in the field since this earlier roadmap, bringing together experts primarily from the UK across the breadth of the photovoltaics community. The focus is both on the challenges in improving the efficiency, stability and levelized cost of electricity of current technologies for utility-scale PVs, as well as the fundamental questions in novel technologies that can have a significant impact on emerging markets, such as indoor PVs, space PVs, and agrivoltaics. We discuss challenges in advanced metrology and computational tools, as well as the growing synergies between PVs and solar fuels, and offer a perspective on the environmental sustainability of the PV industry. Through this roadmap, we emphasize promising pathways forward in both the short- and long-term, and for communities working on technologies across a range of maturity levels to learn from each other.Comment: 160 pages, 21 figure

Mortality Among Adults With Cancer Undergoing Chemotherapy or Immunotherapy and Infected With COVID-19

Importance: Large cohorts of patients with active cancers and COVID-19 infection are needed to provide evidence of the association of recent cancer treatment and cancer type with COVID-19 mortality. // Objective: To evaluate whether systemic anticancer treatments (SACTs), tumor subtypes, patient demographic characteristics (age and sex), and comorbidities are associated with COVID-19 mortality. // Design, Setting, and Participants: The UK Coronavirus Cancer Monitoring Project (UKCCMP) is a prospective cohort study conducted at 69 UK cancer hospitals among adult patients (≥18 years) with an active cancer and a clinical diagnosis of COVID-19. Patients registered from March 18 to August 1, 2020, were included in this analysis. // Exposures: SACT, tumor subtype, patient demographic characteristics (eg, age, sex, body mass index, race and ethnicity, smoking history), and comorbidities were investigated. // Main Outcomes and Measures: The primary end point was all-cause mortality within the primary hospitalization. // Results: Overall, 2515 of 2786 patients registered during the study period were included; 1464 (58%) were men; and the median (IQR) age was 72 (62-80) years. The mortality rate was 38% (966 patients). The data suggest an association between higher mortality in patients with hematological malignant neoplasms irrespective of recent SACT, particularly in those with acute leukemias or myelodysplastic syndrome (OR, 2.16; 95% CI, 1.30-3.60) and myeloma or plasmacytoma (OR, 1.53; 95% CI, 1.04-2.26). Lung cancer was also significantly associated with higher COVID-19–related mortality (OR, 1.58; 95% CI, 1.11-2.25). No association between higher mortality and receiving chemotherapy in the 4 weeks before COVID-19 diagnosis was observed after correcting for the crucial confounders of age, sex, and comorbidities. An association between lower mortality and receiving immunotherapy in the 4 weeks before COVID-19 diagnosis was observed (immunotherapy vs no cancer therapy: OR, 0.52; 95% CI, 0.31-0.86). // Conclusions and Relevance: The findings of this study of patients with active cancer suggest that recent SACT is not associated with inferior outcomes from COVID-19 infection. This has relevance for the care of patients with cancer requiring treatment, particularly in countries experiencing an increase in COVID-19 case numbers. Important differences in outcomes among patients with hematological and lung cancers were observed

PREDIKSI KUANTITAS AIR BERSIH DARI PDAM KABUPATEN KARANGFANYAR DI KECAMATAN MATESIH PADA TAHUN 2025

IsniGhofarSholeh, 2015, “PREDIKSI KUANTITAS AIR BERSIH DARI PDAM KABUPATENKARANGANYAR DI KECAMATAN MATESIH PADA TAHUN 2025”,TugasAkhir, Program D-III TeknikSipilFakultasTeknik, UniversitasSebelasMaretSurakarta. Air merupakan kebutuhan yang sangat penting bagi kelangsungan hidup manusia.Tingkat pertumbuhan penduduk yang tinggi serta besarnya arus urbanisasi menyebabkanbertambahnyakebutuhan air yang dipenuhioleh Perusahaan Daerah Air Minum (PDAM). Dalampemenuhankebutuhan air padaKecamtanMatesihKabupatenKaranganyar, PDAM KabupatenKaranganyarmemanfaatkansumbermata air yang ada. JenisPenelitianiniadalahdeskripsikuantitatif.Studiuntukmengetahuiproduksi air minumdari PDAM KabupatenKaranganyardanmengetahuikebutuhan air bersih di KecamatanMatesihKabupatenKaranganyar. Data yang diperlukandalampenelitianiniadalahjumlahpendudukKecamatanMatesihKabupatenKaranganyar, data debit air yang adamenurut Unit Wilayah di KabupatenKaranganyar. Bertujuanmengetahuihasilprediksijumlahpendudukdanmenurutmetodegeometrik yang digunakanuntukmengetahuihasilprediksikebutuhan air padatahun 2025. Berdasarkananalisis data jumlahpenduduktahun 2025 terdapathasilprediksikebutuhan air bersihpadatahun 2025 di KecamatanMatesihKaranganyarsebesar57.497lt/dt, kebutuhanharianmaksimum12,598 lt/dt, dan debit pada jam puncak16,33lt/dt.HasilperhitunganpadaRancanganAnggaranBiaya (RAB) pemasangansambunganrumahbaru (SR) di KecamatanMatesihKabupatenKaranganyaradalahsebesar Rp.2.280.767,- Kata Kunci :Prediksi,JumlahPenduduk, Kebutuhan Air PDAM