199 research outputs found
Estimación de la conductividad eléctrica del tejido humano en la terapia de hipertermia por radiofrecuencia
- Publication venue
- Universidad Nacional de Colombia
- Publication date
- 01/01/2023
- Field of study
The use of mathematical models to study complex systems such as physical and biological phenomena allows understanding their behavior, specifically regarding variables and parameters that are difficult to obtain. Additionally, studying optimization techniques has made it possible to approximate the characteristics of these systems by correlating numerical simulations and experimentation. Radiofrequency hyperthermia therapy for cancer treatment is currently under consideration for future medical applications. However, some of its properties are complex to measure, which could prevent their control. This is the case of electrical conductivity, which depends on the induction frequency and the tissue characteristics. In this paper, radiofrequency hyperthermia therapy was simulated via the finite element method. Then, an estimation of the electrical conductivity involved in the treatment was performed using the particle swarm optimization method. The execution time and the difference between the estimated parameter and the exact value were evaluated and compared with those obtained using the Levenberg-Marquardt method. The results indicate a significant agreement between the estimated and exact values in three different cases. The Levenberg-Marquardt method has a difference of 0,1942% and a performance time of 22 minutes, whereas the particle swarm optimization method has a difference of 0,0967% and a performance time of 327 minutes. The latter performs better in terms of parameter value estimation, whereas the former has better computational times. These techniques may help medical doctors to prescribe treatment protocols and may open the possibility of devising control strategies for hyperthermia therapy as a cancer treatment.El uso de modelos matemáticos para el estudio de sistemas complejos como los fenómenos físicos y biológicos permite comprender su comportamiento, específicamente con respecto a variables y parámetros difíciles de obtener. Adicionalmente, el estudio de técnicas de optimización ha permitido aproximar las características de estos sistemas por medio de la correlación de simulaciones numéricas y la experimentación. La terapia de hipertermia por radiofrecuencia para el tratamiento del cáncer está actualmente en consideración para su futura aplicación médica. Sin embargo, algunas de sus propiedades son difíciles de medir, lo cual impediría su control. Este es el caso de la conductividad eléctrica, que depende de la frecuencia de inducción y de las características del tejido. En este artículo se simuló la terapia de hipertermia por radiofrecuencia mediante el método de elementos finitos. Luego se realizó una estimación de la conductividad eléctrica en el tratamiento mediante el método de optimización por enjambres de partículas. Se evaluaron el tiempo de ejecución y la diferencia del valor estimado con respecto al valor exacto, y se compararon sus valores estimados con los obtenidos mediante el método de Levenberg-Marquardt. Los resultados indican una concordancia significativa entre los valores estimados y los exactos en tres casos diferentes. El método de Levenberg-Marquardt tiene una diferencia de 0,1942% y un tiempo de ejecución de 22 minutos, mientras que el método de optimización de enjambres de partículas tiene una diferencia de 0,0967% y un tiempo de ejecución de 327 minutos. Este último tiene un mejor rendimiento en términos de estimación del valor de los parámetros, mientras que el otro tiene un mejor tiempo de ejecución computacional. Estas técnicas podrían ayudar a los médicos a prescribir protocolos de tratamiento y abrir la posibilidad de diseñar estrategias de control para la terapia de hipertermia como tratamiento para el cáncer.Fil: Lopez Perez, Jorge Iván. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Ciencias e Ingeniería de la Computación. Universidad Nacional del Sur. Departamento de Ciencias e Ingeniería de la Computación. Instituto de Ciencias e Ingeniería de la Computación; Argentina. Universidad Santiago de Cali; ColombiaFil: Bermeo Varón, L. A.. Universidad Santiago de Cali; Colombi
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- Author
- Abdala Antonio
- Abidi Khalid
- Abillama Fayez François
- Abos Francisco Javier Saenz
- Aboufray Ahmed Ali
- Abregal Giancarlo
- Abroug Fekri
- Achilleos Eleni
- Acosta Ysica
- Adam Višnja Nesek
- Adamina Ileana
- Adams John
- Adamuz Jordi
- Adejumo Prisca Olabisi
- Adekola Oyebola
- Ademokun Jane
- Adenekan Anthony
- Adib Nik Azman Nik
- Adipa Faustina Excel
- Afonso Elsa
- Aganon Ferdinand
- Agarwal Sonika
- Aguirre Joaquin
- Aguirre Lydia Gallego
- Aguirre-Bermeo Hernan
- Ahmad Fatima Kasem El
- Ahmad Meraj
- Ahmed Hazem
- Ahn Jong-Joon
- Ahtiala Maarit
- Akbas Turkay
- Akdağ Devrim
- Akker Mustafa
- Akselsen Gro Ringstad
- Al-Alawi Maram Milud Said
- Alabuzidi Aya
- Alampi Daniela
- Albaiceta Guillermo Muñiz
- Albert Patricia
- Albrecht Lea
- Albrett Jonathan
- Alexandropoulou Paraskevi
- Alexandrou Anna
- Ali Ashwaq
- Ali Mohd Nazri
- Alias Anita
- Alkhumsi Soad Imhmed R.
- Allaert Silvie
- Allison Nicola
- Almekhlafi Ghaleb
- Alonso Helena Fernandez
- Alsheikhly Ahmed Subhy
- Alshrif Abdualhamid I
- Alvarenga Gloria
- Alvarez Diana
- Alvarez Gonzalo Martín
- Alvarez Gustavo Andres
- Alvarez Jorge Duerto
- Alvarez Josep Trenado
- Alvarez Raquel Garcia
- Alves Paulo
- Andersen Marit Hildegunn
- Andersen Yvonne
- Andresen Hanne
- Anisoglou Souzana
- Antonio Maria Gracia San
- Antunes Nelson
- Anvelt Eneli
- Aperocho Cristal April Jane
- Aponte Cesar
- Araya Paola
- Arcas María Luisa Bravo
- Arikan Huseyin
- Arntsen Wenche
- Arteta Arteta Donaldo S.
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- Assiri Amer
- Atchade Enora
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- Attwood Ben
- Aucapina Alejandra
- Avalos Fernando
- Aves Emma
- Avogadro Prune
- Avramopoulou Lamprini
- Ay Mustafa
- Ay Serap Avcı
- Aya Umeda
- Ayala Maria
- Aydemir Semih
- Aydin Demet Tok
- Azencot Mazal
- Azoia Joao
- Baasanjav Battsetseg
- Babych Volodymyr
- Baccaro Fernando
- Badariotti Gustavo
- Bae Jung-Min
- Baek Jonghyun
- Baftiu Nehat
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- Banwarie Preveen
- Bao Guijun
- Baptiste-Savoie Jacqueline
- Barakat-Johnson Michelle
- Barefield Cindy
- Barkas Diane
- Barnes Christopher
- Barone Antonio
- Baronia Arvind
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- Barreiro Emma Moreno
- Barros Elaine
- Barrowcliffe Suzanne
- Barrueco-Francioni Jesus Emilio
- Bartoli Julio Ricardo
- Baruah Rosaleen
- Bascary Carlos Alejandro
- Baskakov Danil
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- Belskiy Vladislav
- Ben-Hamouda Nawfel
- Ben-Jacob Talia
- Benbenishty Julie
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- Benlamin Mohamed
- Berry Gillian
- Bertoletti Fernando Pablo
- Besbes Lamia
- Besbes Lamia Ouanes
- Besch Guillaume
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- Bielskute Egidija
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- Birgisdóttir Hrönn
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- Wahab Sherliza
- Wahlbom Ewa
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- White Joanne
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- Xiao Lina
- Xiao Min
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- Xiaoyan Yang
- Xie Yan
- Xing Cynthia
- Xiong Yunfeng
- Xixi Li
- Xu Lina
- Xu Xiao
- Xu Xuelian
- Xu Yan
- Xue Xiujuan
- Yaghi Aktham
- Yakubu Yakubu H.
- Yamamoto Ryohey
- Yan Howe
- Yan Xiaoli
- Yan Yan
- Yang Fan
- Yang Fengling
- Yang Huai
- Yang Jing
- Yang Lei
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- Yang Shunzhu
- Yang Yanping
- Yang YongXia
- Yao Xiuying
- Yao Yanlan
- Yao Zhiru
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- Ye Mei
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- Yeon-Joo Lee
- Yildiz İsmail
- Yilmaz Hakan
- Yin Hai
- Yin Li
- Young Charlotte
- Young-Jae Cho
- Yu Jing
- Yu Min
- Yu Tingting
- Yu Zhu Jun
- Yuan Cui
- Yuan Weilian
- Yuan Yuxia
- Yuchen Wu
- Yuemen Ly
- Yumei Chen
- Zahra Hajer Ben
- Zainudin Asmah
- Zakalik Graciela
- Zaki Ahmed
- Zalba-Etayo Begoña
- Zamora Purificacion Sanchez
- Zamorano Matias Jesús Flamm
- Zan Tao
- Zand Farid
- Zarei Fatemeh
- Zeng Jing Mei
- Zeng Qi
- Zepoy Sofia
- Zerman Avşar
- Zermeno Jorge Macias
- Zgrzheblovska Lesia
- Zhang Aizhi
- Zhang Baoke
- Zhang Feifei
- Zhang Guiping
- Zhang Hong
- Zhang Hongsu
- Zhang Hui
- Zhang Jing
- Zhang Jundi
- Zhang Libing
- Zhang Ling
- Zhang Na
- Zhang Wei
- Zhang Yali
- Zhang Ying
- Zhang Zhenxia
- Zhao Hui Min
- Zhao Lijuan
- Zhao Lina
- Zhao Qian
- Zhao Qingli
- Zhao Rong Hua
- Zhao Ronghua
- Zhao Wenwen
- Zhao Yingjuan
- Zhedaeva Marina
- Zheng Hong
- Zheng Jing
- Zheng Xianhong
- Zhigang Zhang
- Zhijuan Wang
- Zhiping Sun
- Zhivotneva Trina
- Zhou Yuming
- Zhu Guoyan
- Zhu JiFen
- Zhu Jin Yu
- Zivanovic-Posilovic Gordana
- Zorko Nika
- Zubareva Nadezhda
- Zuev Evgeniy
- Zueva Oksana
- Zulkifli Zulkifli
- Ágoston Zsuzsann
- Åkerman Eva
- Çelik Jale Bengi
- Ñamendys-Silva Silvio A.
- Özcan Beysim
- Özserezli Boğaç
- Ünlü Nurdan
- Čuljak Hemena
- Şentürk Evren
- Šuput Aleksandar
- Publication venue
- 'Organisation for Economic Co-Operation and Development (OECD)'
- Publication date
- 26/02/2021
- Field of study
Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
Recommended from our members
Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
- Author
- Abdala Antonio
- Abidi Khalid
- Abillama Fayez François
- Abos Francisco Javier Saenz
- Aboufray Ahmed Ali
- Abregal Giancarlo
- Abroug Fekri
- Achilleos Eleni
- Acosta Ysica
- Adam Višnja Nesek
- Adamina Ileana
- Adams John
- Adamuz Jordi
- Adejumo Prisca Olabisi
- Adekola Oyebola
- Ademokun Jane
- Adenekan Anthony
- Adib Nik Azman Nik
- Adipa Faustina Excel
- Afonso Elsa
- Aganon Ferdinand
- Agarwal Sonika
- Aguirre Joaquin
- Aguirre Lydia Gallego
- Aguirre-Bermeo Hernan
- Ahmad Fatima Kasem El
- Ahmad Meraj
- Ahmed Hazem
- Ahn Jong-Joon
- Ahtiala Maarit
- Akbas Turkay
- Akdağ Devrim
- Akker Mustafa
- Akselsen Gro Ringstad
- Al-Alawi Maram Milud Said
- Alabuzidi Aya
- Alampi Daniela
- Albaiceta Guillermo Muñiz
- Albert Patricia
- Albrecht Lea
- Albrett Jonathan
- Alexandropoulou Paraskevi
- Alexandrou Anna
- Ali Ashwaq
- Ali Mohd Nazri
- Alias Anita
- Alkhumsi Soad Imhmed R.
- Allaert Silvie
- Allison Nicola
- Almekhlafi Ghaleb
- Alonso Helena Fernandez
- Alsheikhly Ahmed Subhy
- Alshrif Abdualhamid I
- Alvarenga Gloria
- Alvarez Diana
- Alvarez Gonzalo Martín
- Alvarez Gustavo Andres
- Alvarez Jorge Duerto
- Alvarez Josep Trenado
- Alvarez Raquel Garcia
- Alves Paulo
- Andersen Marit Hildegunn
- Andersen Yvonne
- Andresen Hanne
- Anisoglou Souzana
- Antonio Maria Gracia San
- Antunes Nelson
- Anvelt Eneli
- Aperocho Cristal April Jane
- Aponte Cesar
- Araya Paola
- Arcas María Luisa Bravo
- Arikan Huseyin
- Arntsen Wenche
- Arteta Arteta Donaldo S.
- Ashour Firas
- Assiri Amer
- Atchade Enora
- Ateya Zainab
- Attwood Ben
- Aucapina Alejandra
- Avalos Fernando
- Aves Emma
- Avogadro Prune
- Avramopoulou Lamprini
- Ay Mustafa
- Ay Serap Avcı
- Aya Umeda
- Ayala Maria
- Aydemir Semih
- Aydin Demet Tok
- Azencot Mazal
- Azoia Joao
- Baasanjav Battsetseg
- Babych Volodymyr
- Baccaro Fernando
- Badariotti Gustavo
- Bae Jung-Min
- Baek Jonghyun
- Baftiu Nehat
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- Nshimyumuremyi Isaac
- Nunes Catarina
- Nuñez Cesar Rodriguez
- Nyhus Marit
- Nzarora Josue
- Ochoa Maria-Elena
- Odenthal Tobias
- Ogbeide Vongayi
- Ohuchi Akira
- Oikonomou Mrina
- Oiting Oscar
- Olanipekun Simeon
- Olivares Pablo Garcia
- Oliveira Evellyn
- Olsen Brita Fosser
- Onelli Adriana
- Onrust Marisa
- Onyeka Tonia
- Orozco Estefania
- Orvelius Lotti
- Ory Solenne
- Osei Irene Pearl
- Ostenjo Hege
- Ouyang Fei
- Owens Daniel
- Owojuyigbe Afolabi
- Ozgultekin Asu
- O’Brien Catherine
- O’Donnell Caroline
- O’Nuallain Siobhan
- O’Shea Aidan
- O’Shea Fiona
- Pacturanan Michelle
- Paddle Jonathan
- Padilla Nayeli Rocio Cañas
- Pagella Gonzalo
- Pagioulas Konstantinos
- Paillet Caroline
- Palaez Carolina
- Palfreeman Christopher
- Palfrey Ruth
- Palmu Auli
- Palo Jose Emmanuel
- Pan Fuqun
- Pang Xuelian
- Panka Bernardo
- Pantaleao Taís
- Pantelas Nikolaos
- Pantiora Eirini
- Papadopoulos Dimitrios
- Papageorgiou Eirini
- Papanikolaou Metaxia
- Papathanakos Georgios
- Papavasilopoulou Theonymfi
- Parag Nivisha
- Parente Isabel
- Park Jisoo
- Park Seung Yong
- Park So Young
- Park Sunghoon
- Park Tai Sun
- Parke Rachael
- Parkin Emma
- Parsons Leanne
- Parsons Penny
- Pascual-Bielsa Ana
- Pastore Beatrice
- Pastores Stephen M.
- Pathak Sabina Dhakal
- Patrichi Tatiana
- Patsalos Artemis
- Patsiou Eirini-Chysovalanto
- Pavlisa Gordana
- Pedersen Anne Sofie Bomholt
- Pedersen Karin Rehnholt
- Pederzani Marcelo
- Pedro Laura
- Peipei Xu
- Peker Nebia
- Peltomaa Minna
- Pelz Sabrina
- Pena José Manuel Garcia
- Peratoner Alberto
- Pereira Jorge
- Perez Hugo
- Perez-Torres David
- Perez-Vacas Jonathan
- Perme Janja
- Peterson Jessica
- Petosic Antonija
- Petrisor Cristina
- Petrushin Maxim
- Pečenković Suzana
- Philippart François
- Piergentili Federica
- Pili-Floury Sébastien
- Pillard Cindy
- Pineda Ana Alícia Velarde
- Pinheiro Cristiana Mota
- Pinto Susana
- Pinto Vitor Manuel Vaz
- Piradov Michael
- Pires Filpe
- Pivkina Alexandra
- Piza Petr
- Piñan Isabel Santín
- Plantefève Gaëtan
- Pleitinckx Vincianne
- Polgarova Petra
- Polo Ana Belén Curto
- Popescu Mihai
- Popescu Monica
- Potestio Christopher
- Powell Madeleine
- Preda Gabriel
- Prol-Silva Estefanía
- Prowle John
- Psarulis Konstantinos
- Pulak Paul
- Pulletz Mark
- Putruele Sofia
- Qawasmeh Khaled Al
- Qiao Hongmei
- Quagliotto Catia
- Quaini Attilio
- Quintard Hervé
- Quiroga Cristian
- Rabarova Daria
- Radavidson Anthony
- Radivojevic Renata Curic
- Rahim Azmin Huda Abdul
- Raimondo Arena
- Raitsiou Bogdan
- Raizman Rose
- Raj Ashok Sundai
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- Rajković Marija
- Ramaker Bart
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- Ramirez Mario
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- Ran Qiong
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- Rapley Jackie
- Rastegar Touraj
- Ratnam Shanthi
- Ratnam Shanti
- Ravani Ifigenia
- Reece-Anthony Rosie
- Reidinga Auke
- Reijntjens Jennifer
- Remor Natalie
- Ren Aiua
- Reyes Amylkar Garay
- Reyes Amylkar José Garay
- Reyes Laura Martinez
- Reyes Paul Eric
- Reynolds Claire
- Ribas Antoni Margarit
- Ribas Antonio Margarit
- Riera Alba
- Riessen Reimer
- Ringdal Mona
- Rinket Martin
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- Rita Clara Santa
- Rivas Juan Carlos
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- Riveiro Marilyn
- Rizzo Antonino
- Rocco Monica
- Rocha Pamela
- Rodriguez Gabriel Enrique
- Rojas-Suarez José
- Rokosh Ella
- Roller Martin
- Roman-Pognuz Erik
- Romero-Gonzalez Juan P.
- Ronchini Ana Lucia Vitti
- Rooney Glenda
- Rosado Ines
- Rosalia Rodney
- Rosati Moris
- Rose Bernd Oliver
- Rose Louise
- Rostello Oscar Fernández
- Rothenfusser Monika
- Rubulotta Francesca
- Rubulotta Giorgia
- Rygvadottir Brynja
- Saager Leif
- Sabbag Ignacio
- Saha Rajnish
- Sakki Jenni-Katarina
- Sakuramoto Hideaki
- Salazar Janel
- Salberg Armorel
- Salman Fatema
- Salo Swagotika
- Salvà-Costa Vicent
- Samat Noryani Mohd
- Sanchez Losune Cano
- Sanchez Maria Angeles Hurtado
- Sanchez-Hurtado Luis Alejandro
- Sandberg Ulla
- Sandesc Dorel
- Sankar-Maharaj Sasha
- Sankey Babangida John
- Santiago Eleanor
- Santos Jacinta
- Santos Rayanne
- Sanz Luz Coronado
- Sanz Miquel
- Sarkar Nikki
- Saul Pablo
- Sawawiboon Chaiwut
- Schaller Stefan
- Schallom Marilyn
- Schefold Joerg C.
- Schmidt Raysa Cristina
- Schmollgruber Shelley
- Schmukler Armando
- Schmutz René
- Schulze Tobias
- Schüppel Sebastian
- Scire Giovanni
- Scutariu Monica Adriana
- Sellami Walid
- Sepulveda Maria Idalia
- Sergeev Dmitry
- Serin Sibel Ocak
- Seromenho Vanda
- Serpa Leticia
- Sertznig Claude
- Setten Mariano
- Shah Bhagyesh
- Shao Hongyan
- Shaw David
- Shawish Sabah Abu
- Shayamano Rosina
- Sheehan Christine
- Shen Yanling
- Sherwin James
- Shi Guanxiu
- Shi Zeya
- Shime Nobuaki
- Shimizu Masako
- Short Jack
- Shosholcheva Mirjana
- Shosolcheva Mirjana
- Sierra Rafael
- Sills Martin
- Silva Pedro
- Sim Yun Su
- Simi Marcelo
- Simon Philipp
- Singh Keevan
- Singh Mukta
- Sjobo Britt
- Skorstad Elin Mari
- Slobodianiuk Gari
- Slobodianiuk Garri
- Smajic Jasmina
- Smiley Kathleen Ann
- Smith Catherine
- Smith Chris
- Smith Julie
- Smith Neil
- Smith Orla
- Smith Samantha
- Soledad Javiera
- Somerville Justine
- Sona Carrie
- Song Bing
- Song Caiju
- Song JinHui
- Song Min
- Song Rima
- Sosa Miguel Ángel
- Sosnowski Kellie
- Sostaric Maja
- Soula Enas
- Soulisse Léa
- Soundoulounaki Stella
- Souppart Virginie
- Sourla Evdokia
- Sousa Bruno
- Spadaro Savino
- Spina Rosario
- Spyropoulou Anastasia
- Spångfors Martin
- Stafylaraki Maria
- Staikos Ioannis
- Stalika Kristina Mariana Matei
- Stanojević Maja
- Starchenko Irina
- Stefanovic Branislava
- Steffenak Elin
- Stehr Sebastian
- Stenset Ane
- Stiban Sonia
- Stivanello Lucia
- Stojanovic Milena
- Stones Elizabeth
- Straede Esben
- Stübner Andeas
- Subedi Nisha Bhandari
- Suen Gabriel
- Sulaiman Siti Rohayah
- Sun Chengxia
- Sun Wei
- Sun Yue
- Susanti Ade
- Sustic Alan
- Swinnen Walter
- Syed Muhommed Ridwaan
- Sykehus Drammen
- Szakmany Tamas
- Sánchez-Hurtado Luis
- Tababa Osama Wanees Emhemid
- Tabah Alexis
- Tabib Majd
- Taghavi Noushin
- Taibi Maria Rosa
- Taito Shunsuke
- Tak Poon Shing
- Takahashi Kenji
- Talik Imen
- Tallot Mandy
- Tamayo Luis Mario
- Tamme Kadri
- Tan Lei
- Tao Jing
- Tapia Fernando
- Tavares Ana
- Taşdemir Banu
- Teig Magnus
- Tejeda-Huezo Brigitte
- Telleria Vanesa Mercado
- Templeton Mae
- Terry Dorothy
- Tervo-Heikkinen Tarja
- Thankamma Bindu
- Theisen Christian
- Thix Cyril
- Tholioti Thomai
- Thoma Giannoula
- Thomas Beverley
- Thompson Amy
- Thompson Lorraine
- Thomsen Tina Damgaar
- Thorpe Elaine
- Tian Eryun
- Tian Xiao Fang
- Tian Yani
- Tian Zhixia
- Timsit Jean-Francois
- Tingsvik Catarina
- Tirado Celia
- Toellefsen Annette
- Tokareva Ekaterina
- Tokur Murat Emre
- Tole Eunice
- Tomescu Dana
- Tong Jenny May Geok
- Tonkovic Dinko
- Toppin Patrick
- Torlinski Tomasz
- Traina Lidia
- Tranello Francesca Paola
- Tribulev Maksim
- Tridente Ascanio
- Triki Ahmed Ramadan
- Tripathy Swagata
- Trongtrakul Konlawij
- Trongtratul Konlawij
- Trposak Angela
- Trudvang Siw
- Trueman-Dawkins Treiza
- Tsarev Alexander
- Tsikriki Syragoula
- Tsikritsaki Kyriaki
- Tsujimoto Mayumi
- Tubacka Marta
- Tuinstra Binny
- Tuo Lili
- Turan Can
- Turan Sema
- Turc Jean
- Turner Sarah Jane
- Turčan Anton
- Tutillo Diego Rolando Morocho
- Twagirumugabe Theogene
- Twiggs Hilary
- Uba Stella
- Uccelli Francesco
- Udiljak Nikolina
- Ugwu Innocent
- Umek Nejc
- Undar Hasan Nabi
- Vakalos Aristeidis
- Valerio Idália
- Valgolio Emanuel
- Valta Maija
- Valta Maija Anniina
- van Axel Alisha
- Van Cotthem Ilse
- Van de Velde Stijn
- Van Den Berg Lettie
- Van Den Brink Mark
- Van Den Elst Arlette
- van der Kuil Mark
- Van Gulik Laura
- Van Regenmortel Niels
- Van Vliet Peter
- Vanroest Margijske
- Varela Maria
- Vaschetto Rosanna
- Vasquez Alexandra
- Vaughan-Jones Nicola
- Velickovic Jelena
- Veličković Dejan
- Ventour Dale
- Vermeijden Jan Wytze
- Vieira João
- Villa Robert
- Villafuerte Missael Vladimir Espinoza
- Villanueva Ximena
- Villegas Paula
- Viveiros Abel
- Vizcaychipi Marcela
- Vlaovic Janko
- Vochin Ana
- Volta Carlo Alberto
- von der Osten Ingrid
- Von Der Osten Ingrid
- von Lewinski Dirk
- Vosylius Saulius
- Vuković Anita
- Vullum Sylvi
- Vymazal Tamas
- Vymazal Tomas
- Wahab Sherliza
- Wahlbom Ewa
- Waibel Hansjoerg
- Wallin Ewa
- Walsh Amy
- Wan Jianhong
- Wan Yan
- Wang Damei
- Wang Fanglan
- Wang GuoXian
- Wang Hai Yun
- Wang Haiyan
- Wang Jing
- Wang Kefang
- Wang LingLing
- Wang RuiXia
- Wang Shuhui
- Wang Shuo
- Wang Wei
- Wang Wenmei
- Wang Xiaomin
- Wang Yan
- Wang Ying
- Wang Yingli
- Wang Yuping
- Wang Yuxia
- Watts Stacey
- Waweru-Siika Wangari
- Wei Dongfang
- Wei Wei
- Wei Xiyan
- Wei Ying
- Welters Ingeborg D.
- White Joanne
- White Nigel
- Whiteley Simon
- Whitticase Richard
- Wiborg Elisabeth
- Wijnands Patricia
- Wilby Liz
- Williams Anne
- Williams Ged
- Williams Helen
- Williams Karen
- Williams Lynne
- Wilting Rob
- Wise Robert
- Woods Justin
- Wright Kerry
- Wu Juan
- Wu ShiFen
- Wu Xiaojun
- Wu Xiaoying
- Wu Yang
- Wu Yun
- Wu Zijing
- Xhindi Nordian
- Xia Chun Jie
- Xia Xinhua
- Xiao Lina
- Xiao Min
- Xiao Yan
- Xiaoyan Yang
- Xie Yan
- Xing Cynthia
- Xiong Yunfeng
- Xixi Li
- Xu Lina
- Xu Xiao
- Xu Xuelian
- Xu Yan
- Xue Xiujuan
- Yaghi Aktham
- Yakubu Yakubu H.
- Yamamoto Ryohey
- Yan Howe
- Yan Xiaoli
- Yan Yan
- Yang Fan
- Yang Fengling
- Yang Huai
- Yang Jing
- Yang Lei
- Yang Qiao
- Yang Shunzhu
- Yang Yanping
- Yang YongXia
- Yao Xiuying
- Yao Yanlan
- Yao Zhiru
- Ye Man
- Ye Mei
- Yeni Nomhle Princess
- Yeon-Joo Lee
- Yildiz İsmail
- Yilmaz Hakan
- Yin Hai
- Yin Li
- Young Charlotte
- Young-Jae Cho
- Yu Jing
- Yu Min
- Yu Tingting
- Yu Zhu Jun
- Yuan Cui
- Yuan Weilian
- Yuan Yuxia
- Yuchen Wu
- Yuemen Ly
- Yumei Chen
- Zahra Hajer Ben
- Zainudin Asmah
- Zakalik Graciela
- Zaki Ahmed
- Zalba-Etayo Begoña
- Zamora Purificacion Sanchez
- Zamorano Matias Jesús Flamm
- Zan Tao
- Zand Farid
- Zarei Fatemeh
- Zeng Jing Mei
- Zeng Qi
- Zepoy Sofia
- Zerman Avşar
- Zermeno Jorge Macias
- Zgrzheblovska Lesia
- Zhang Aizhi
- Zhang Baoke
- Zhang Feifei
- Zhang Guiping
- Zhang Hong
- Zhang Hongsu
- Zhang Hui
- Zhang Jing
- Zhang Jundi
- Zhang Libing
- Zhang Ling
- Zhang Na
- Zhang Wei
- Zhang Yali
- Zhang Ying
- Zhang Zhenxia
- Zhao Hui Min
- Zhao Lijuan
- Zhao Lina
- Zhao Qian
- Zhao Qingli
- Zhao Rong Hua
- Zhao Ronghua
- Zhao Wenwen
- Zhao Yingjuan
- Zhedaeva Marina
- Zheng Hong
- Zheng Jing
- Zheng Xianhong
- Zhigang Zhang
- Zhijuan Wang
- Zhiping Sun
- Zhivotneva Trina
- Zhou Yuming
- Zhu Guoyan
- Zhu JiFen
- Zhu Jin Yu
- Zivanovic-Posilovic Gordana
- Zorko Nika
- Zubareva Nadezhda
- Zuev Evgeniy
- Zueva Oksana
- Zulkifli Zulkifli
- Ágoston Zsuzsann
- Åkerman Eva
- Çelik Jale Bengi
- Ñamendys-Silva Silvio A.
- Özcan Beysim
- Özserezli Boğaç
- Ünlü Nurdan
- Čuljak Hemena
- Şentürk Evren
- Šuput Aleksandar
- Publication venue
- Intensive Care Medicine
- Publication date
- 09/04/2021
- Field of study
The original version of this article unfortunately contained a mistake
Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
- Author
- Aaron Joffe
- Aaron Mark Hernandez
- Aaron Mark Hernandez
- Abby Lewis
- Abdelhamid Hachimi
- Abdualhamid I Alshrif
- Abel Viveiros
- Abhijit Duggal
- Abidin Oner Balbay
- Achilleas Chovas
- Ade Susanti
- Adi Hadzibegovic
- Adonis Dungca
- Adrian Belii
- Adrian Belii
- Adriana Onelli
- Afolabi Owojuyigbe
- Agnieszka Kubisz-Pudelko
- Agnès Blanc
- Ahmed Ali Aboufray
- Ahmed Elhadi
- Ahmed Ramadan Triki
- Ahmed Subhy Alsheikhly
- Ahmed Zaki
- Ahmet Eroglu
- Aidan O'Shea
- Aikaterini Dimoula
- Aikaterini Efthimiou
- Aikaterini Flevari
- Ailesh Corcoran
- AiPing Bi
- Aiua Ren
- Aizhi Zhang
- Ajitha Rajendran
- Akemi Hirao
- Akira Ohuchi
- Aktham Yaghi
- Ala Khaled
- Alan Sustic
- Alan Sustic
- Alba Riera
- Alban Greca
- Alberto de Jesús Ortiz
- Alberto Peratoner
- Alejandra Aucapina
- Alejandra Azahara Marguello Fernandez
- Alejandro Ibarra
- Aleksandar Šuput
- Aleksandra Gutysz-Wojnicka
- Alessandra Negro
- Alessandro Di Risio
- Alessandro Galazzi
- Alexander Dullenkopf
- Alexander Kiselev
- Alexander Tsarev
- Alexandra Pivkina
- Alexandra Vasquez
- Alexis Tabah
- Ali Kağnıcı
- Alida Moise
- Aline Ramalho
- Alinoy Lavy
- Alisha van Axel
- Alma Cani
- Alvaro Ortega Guerrero
- Amalia Corso
- Amber Markham
- Amelia Ferreira
- Amer Assiri
- Amilcar Garcia
- Amilcar Garcia
- Amit Gupta
- Amit Gupta
- Amy Collins
- Amy Thompson
- Amy Walsh
- Amylkar Garay Reyes
- Amylkar José Garay Reyes
- Ana Alabart Llinas
- Ana Alícia Velarde Pineda
- Ana Bantar
- Ana Belén Curto Polo
- Ana Belén Sánchez de la Ventana
- Ana Diaz
- Ana Diaz
- Ana Isabel Clement
- Ana Laura Gonzalez
- Ana Lucia Vitti Ronchini
- Ana Margarida Feranandes
- Ana María De Pablo
- Ana Pascual-Bielsa
- Ana Tavares
- Ana Vochin
- Ana Wensell Fernández
- Anastasia Spyropoulou
- Anastasio Espejo Cano
- Andeas Stübner
- Andrea Bruni
- Andrea Cortegiani
- Andrea Cortegiani
- Andrea Cortegiani
- Andrea Giampaoletti
- Andrea Martonova
- Andrea Martonova
- Andrea McDonnell
- Andrea McLucas
- Andrej Markota
- Andrijan Kartalov
- Andréa Maria Laizner
- Andréa Maria Laizner
- Andréa Maria Laizner
- Ane Stenset
- Angela Trposak
- Angelica Olivetto de Almeida
- Anisette Hoegenhaven
- Anita Alias
- Anita Jans
- Anita Vuković
- Anita-Chrysolyte Kusi-Appiah
- Anja Diers
- Anja Hansen
- Ann-Sofie Malvemyr
- Anna Alexandrou
- Anna Diaz
- Anna Efthymiou
- Anna Kyriakoudi
- Anna Leonova
- Anna Vita Bruno
- Anne Fishman
- Anne Langvad
- Anne Marie Kodal
- Anne Sofie Bomholt Pedersen
- Anne Williams
- Anne-Sophie Debue
- Annette Carey
- Annette Toellefsen
- Anthony Adenekan
- Anthony Radavidson
- Antigoni Karathanou
- Anton Turčan
- Antonella Cotoia
- Antonella Mo
- Antoni Margarit Ribas
- Antonia Liarmakopoulou
- Antonija Petosic
- Antonino Rizzo
- Antonio Abdala
- Antonio Barone
- Antonio Landaverde
- Antonio Manzo
- Antonio Margarit Ribas
- Antony Eneas
- Apostolos Bakas
- Arena Raimondo
- Arif Moghal
- Aristeidis Vakalos
- Arlette Van Den Elst
- Armanda Bozena
- Armando Schmukler
- Armorel Salberg
- Artemis Patsalos
- Arturo Briva
- Arvind Baronia
- Asbjorn Blondal
- Ascanio Tridente
- Ashish K Khanna
- Ashish K Khanna
- Ashish Khanna
- Ashley Szabo Eltorai
- Ashok Sundai Raj
- Ashwaq Ali
- Asmah Zainudin
- Asu Ozgultekin
- Ata Mahmoodpoor
- Athena Lavrentieva
- Attilio Quaini
- Audrey Fioretti
- Audrey Massard
- Auke Reidinga
- Auli Palmu
- Avşar Zerman
- Aya Alabuzidi
- Ayako Noguchi
- Ayça Gümüş
- Azmin Huda Abdul Rahim
- Babangida John Sankey
- Badiola Hilario
- Banu Taşdemir
- Baoke Zhang
- Barbara Garcia
- Barbro Meland
- Bart Ramaker
- Basri Mat Nor
- Battsetseg Baasanjav
- Başar Erdivanli
- Başar Erdivanli
- Beatrice Pastore
- Begoña Zalba-Etayo
- Belen Burgos Conde
- Belinda Guadi-Gosh
- Ben Attwood
- Benjamin Bongiorno
- Benjamin Gerretsen
- Benoît Chinardet
- Berenice Navarro
- Bernardo Panka
- Bernardo Panka
- Bernd Oliver Rose
- Bert Loef
- Betty Star Kampayana
- Beverley Thomas
- Beysim Özcan
- Beysim Özcan
- Bhagyesh Shah
- Biljana Kuzmanovska
- Bindu Thankamma
- Bing Song
- Binny Tuinstra
- Birgitte Fosser Johansen
- Birthe Husted
- Biyan Li
- Bjoern Monsen
- Bjorn Bratsberg
- Bodin Khwannimit
- Bogdan Raitsiou
- Bojan Jovanovic
- Bonnie Bowes
- Boğaç Özserezli
- Bram Kilapong
- Bram Kilapong
- Branislava Stefanovic
- Brian Marsh
- Brigitte Tejeda-Huezo
- Brita Fosser Olsen
- Britt Galaaen
- Britt Sjobo
- Britta Jepsen
- Bronagh Blackwood
- Bruno Miguel Bispo
- Bruno Sousa
- Bruno Sousa
- Brynja Rygvadottir
- Burhan Hadri
- Burhan Hadri
- Byung Ju Kang
- Caihong Hui
- Caiju Song
- Caitriona Cody
- Can Turan
- Carita Löfqvist
- Carlo Alberto Volta
- Carlos Alejandro Bascary
- Carlos Castro Delgado
- Carmel Chapman
- Carmel Georgiev
- Carmen Partera Luque
- Carmen Velasco Guillén
- Carole Boulanger
- Carole Boulanger
- Carole Brett
- Carolina Garzón-Tovar
- Carolina Palaez
- Caroline Lagerhäll
- Caroline O'Donnell
- Caroline Paillet
- Carrie Sona
- Casiano Barrera Groba
- Catalin Traian Guran
- Catarina Nunes
- Catarina Tingsvik
- Catherine Motherway
- Catherine O'Brien
- Catherine Smith
- Cathy Becker
- Catia Quagliotto
- Cecilia Inés Loudet
- Cecilia Loudet
- Celia Tirado
- Ceri Lynch
- Cesar Aponte
- Cesar Rodriguez Nuñez
- Chaiwut Sawawiboon
- Chaoqun Ma
- Charalampos Martinos
- Charalice Ramiro
- Charikleia Nikolaou
- Charlotte Carter
- Charlotte Young
- Charlotte Young
- Chen Yumei
- Cheng
- Chenghau Mu
- Chengxia Sun
- Cheryl Bealer
- Cheryl Davidson
- Chiara Gatti
- Chiara Megna
- Chiara Megna
- Cho Young-Jae
- Chris Gerome Ellazar
- Chris Smith
- Chrisi Diakaki
- Christian Ferretti
- Christian Frey
- Christian Theisen
- Christiana Chime
- Christine Fiedler
- Christine Sheehan
- Christophe Borin
- Christophe Giacardi
- Christopher Barnes
- Christopher Barnes
- Christopher Palfreeman
- Christopher Potestio
- Christos Christofis
- Christos Dragoumanis
- Chrysanthos Markoulias
- Chrysostomos Katsenos
- Chun Jie Xia
- Chunxia Li
- Cindy Barefield
- Cindy Pillard
- Cintia Valencia Hurtado
- Cinzia Borgognoni
- Claire Derbyshire
- Claire Randell
- Claire Reynolds
- Clara Hurtado
- Clara Santa Rita
- Clare Fielding
- Clare Howcroft
- Claude Sertznig
- Claudia Lizbeth Lopez Nava
- Claudia Martins
- Congcong Liu
- Constantina Constantinou
- Cristal April Jane Aperocho
- Cristian Quiroga
- Cristiana Mota Pinheiro
- Cristina Paños Espinosa
- Cristina Petrisor
- Cui Yuan
- Cynthia Xing
- Cyril Thix
- Cyril Thix
- Cédric Bruel
- Cédric Daubin
- Dagmar Holmquist
- Daira Gonzalez
- Daisy Mehay
- Dale Ventour
- Damei Wang
- Damien O'Connell Rosemary Finn
- Dana Tomescu
- Dana Tomescu
- Danca Lančaričová
- Daniel Blanco
- Daniel Horner
- Daniel Owens
- Daniel Sancho Muriel
- Daniela Alampi
- Daniela Carmen Filipescu
- Danielle Hacking
- Danil Baskakov
- Daria Rabarova
- Dassy Levy
- David De Bels
- David Higgins
- David Perez-Torres
- David Shaw
- Davide Massimo Ghioldi
- Dea Mahanes
- Debbie Noblezada-Uy
- Deborah Jibrin
- DeHong Lei
- Deirdre Doyle
- Dejan Veličković
- Delmiro Becker
- Delphine Ngo
- Demet Tok Aydin
- Detlef Kindgen-Milles
- Devrim Akdağ
- Deyan Cao
- Diana Alvarez
- Diane Barkas
- Dianne Figaro-Barclay
- Dick Nahar
- Diego Rolando Morocho Tutillo
- Dimitra Lepida
- Dimitrios Papadopoulos
- Dinko Tonkovic
- Dirk von Lewinski
- Dmitriy Galishevskiy
- Dmitry Sergeev
- Dolly Mabel Bordon Cabral
- Dominic Carney
- Donaldo S Arteta Arteta
- Dongfang Wei
- Dongliang Lin
- Dongmei Bai
- Dongshu Ni
- Donna Cummings
- Dorel Sandesc
- Dorothee Mueller
- Dorothy Terry
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- Xu Peipei
- Xue Lin
- Xue Qin Li
- Xuejuan Liang
- XueLian Liu
- Xuelian Pang
- Xuelian Xu
- Xueping Jiao
- Yajun Ding
- Yakubu H Yakubu
- Yali Zhang
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- Yanming Ding
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- Yanping Yang
- Yasser Mandourah
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- Yenny Cardenas
- Yesim Serife Bayraktar
- Yin He
- Ying Cao
- Ying Li
- Ying Liu
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- Ying Wei
- Ying Zhang
- Yingjuan Zhao
- Yingli Wang
- Yinhua Guo
- Yolanda Mendiara
- YongXia Yang
- Yoshimasa Nishime
- Yoshiro Hayashi
- Youjin Chang
- Youru Jiang
- Youssef Zied Elhechmi
- Ysica Acosta
- Yu Chao
- Yu Han
- Yu Liu
- Yu Liu
- Yue Sun
- Yue Ying Gong
- Yuming Zhou
- Yun Su Sim
- Yun Wu
- Yunchun Dong
- Yunfeng Xiong
- Yupeng Liu
- Yuping Wang
- Yuxia Huo
- Yuxia Wang
- Yuxia Yuan
- Yvan Fleury
- Yvonne Andersen
- Zainab Ateya
- Zaneta Bogoevska-Miteva
- Zeya Shi
- Zhang Zhigang
- ZhangShuangzi Li
- ZhangXia Feng
- Zhaoxia Feng
- Zhaoxing Dai
- Zhenxia Zhang
- Zhihong Chen
- Zhiru Yao
- Zhixia Jiang
- ZhiXia Jiang
- Zhixia Tian
- Zhu Jun Yu
- Zhuqing Li
- Zied Hajjej
- Zijing Wu
- Zsuzsann Ágoston
- Zu Qing Cao
- Zulkifli Zulkifli
- Ângela Lima
- Publication venue
- Intensive Care Medicine
- Publication date
- 29/08/2020
- Field of study
Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
Centrality evolution of the charged-particle pseudorapidity density over a broad pseudorapidity range in Pb-Pb collisions at root s(NN)=2.76TeV
- Author
- Adam Jaroslav
- Adam Jaroslav
- Adamová Dagmar
- Adamová Dagmar
- Aggarwal Madan Mohan
- Aggarwal Madan Mohan
- Aglieri Rinella Gianluca
- Aglieri Rinella Gianluca
- Agnello Michelangelo
- Agnello Michelangelo
- Agrawal Neelima
- Agrawal Neelima
- Ahammed Zubayer
- Ahammed Zubayer
- Ahn Sang Un
- Ahn Sang Un
- Aiola Salvatore
- Aiola Salvatore
- Akindinov Alexander
- Akindinov Alexander
- Alam Sk Noor
- Alam Sk Noor
- Aleksandrov Dmitry
- Aleksandrov Dmitry
- Alessandro Bruno
- Alessandro Bruno
- Alexandre Didier
- Alexandre Didier
- Alfaro Molina Jose Ruben
- Alfaro Molina Jose Ruben
- Alici Andrea
- Alici Andrea
- Alkin Anton
- Alkin Anton
- Almaraz J.R.M.
- Almaraz J.R.M.
- Alme Johan
- Alme Johan
- Alt Torsten
- Alt Torsten
- Altinpinar Sedat
- Altinpinar Sedat
- Altsybeev Igor
- Altsybeev Igor
- Andrei Cristian
- Andrei Cristian
- Andronic Anton
- Andronic Anton
- Anguelov Venelin
- Anguelov Venelin
- Anielski Jonas
- Anielski Jonas
- Antinori Federico
- Antinori Federico
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- Antičić Tome
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- Antonioli Pietro
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- Aphecetche Laurent Bernard
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- Appelshäuser Harald
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- Arnaldi Roberta
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- Arnold Oliver Werner
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- Arslandok Mesut
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- Audurier Benjamin
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- Augustinus Andre
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- Azmi Mohd Danish
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- Badalà Angela
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- Figueredo Marcel Araujo Silva
- Filchagin Sergey
- Filchagin Sergey
- Filho Elienos Pereira de Oliveira
- Filho Elienos Pereira de Oliveira
- Finogeev Dmitry
- Finogeev Dmitry
- Fionda Fiorella Maria Celeste
- Fionda Fiorella Maria Celeste
- Fiore Enrichetta Maria
- Fiore Enrichetta Maria
- Fleck Martin Gabriel
- Fleck Martin Gabriel
- Floris Michele
- Floris Michele
- Foertsch Siegfried Valentin
- Foertsch Siegfried Valentin
- Foka Panagiota
- Foka Panagiota
- Fokin Sergey
- Fokin Sergey
- Fragiacomo Enrico
- Fragiacomo Enrico
- Francescon Andrea
- Francescon Andrea
- Frankenfeld Ulrich
- Frankenfeld Ulrich
- Fuchs Ulrich
- Fuchs Ulrich
- Furget Christophe
- Furget Christophe
- Furs Artur
- Furs Artur
- Fusco Girard Mario
- Fusco Girard Mario
- Gaardhøje Jens Jørgen
- Gaardhøje Jens Jørgen
- Gagliardi Martino
- Gagliardi Martino
- Gago Medina Alberto Martín
- Gago Medina Alberto Martín
- Gallio Mauro
- Gallio Mauro
- Gangadharan Dhevan Raja
- Gangadharan Dhevan Raja
- Ganoti Paraskevi
- Ganoti Paraskevi
- Gao C.
- Gao C.
- Garabatos Chilo
- Garabatos Chilo
- Garcia-Solis Edmundo Javier
- Garcia-Solis Edmundo Javier
- García Martínez Ginés
- García Martínez Ginés
- Gargiulo Corrado
- Gargiulo Corrado
- Gasik Piotr
- Gasik Piotr
- Gauger Erin Frances
- Gauger Erin Frances
- Germain Marie
- Germain Marie
- Gheata Andrei George
- Gheata Andrei George
- Gheata Mihaela
- Gheata Mihaela
- Ghosh Premomoy
- Ghosh Premomoy
- Ghosh Sanjay Kumar
- Ghosh Sanjay Kumar
- Gianotti Paola
- Gianotti Paola
- Giubellino Paolo
- Giubellino Paolo
- Giubilato Piero
- Giubilato Piero
- Glässel Peter
- Glässel Peter
- Godoy Denise Aparecida Moreira de
- Godoy Denise Aparecida Moreira de
- Gonzalez Ferreiro Elena
- Gonzalez Ferreiro Elena
- Gonzalez Victor
- Gonzalez Victor
- González Zamora Pedro
- González Zamora Pedro
- Gorbunov Sergey
- Gorbunov Sergey
- Gotovac Sven
- Gotovac Sven
- Grabski Varlen
- Grabski Varlen
- Grachov O.A.
- Grachov O.A.
- Graczykowski Łukasz Kamil
- Graczykowski Łukasz Kamil
- Graham Katie Leanne
- Graham Katie Leanne
- Grelli Alessandro
- Grelli Alessandro
- Grigoras Alina Gabriela
- Grigoras Alina Gabriela
- Grigoraș Costin
- Grigoraș Costin
- Grigoriev Vladislav A.
- Grigoriev Vladislav A.
- Grigoryan Ara
- Grigoryan Ara
- Grigoryan Smbat
- Grigoryan Smbat
- Grinyov Boris V.
- Grinyov Boris V.
- Grion Nevio
- Grion Nevio
- Gronefeld Julius Maximilian
- Gronefeld Julius Maximilian
- Grossiord Jean-Yves
- Grossiord Jean-Yves
- Grosso Raffaele
- Grosso Raffaele
- Große-Oetringhaus Jan Fiete
- Große-Oetringhaus Jan Fiete
- Guber Fedor
- Guber Fedor
- Guernane Rachid
- Guernane Rachid
- Guerzoni Barbara
- Guerzoni Barbara
- Gulbrandsen Kristjan Herlache
- Gulbrandsen Kristjan Herlache
- Gunji Taku
- Gunji Taku
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- Gupta Anik
- Gupta Ramni
- Gupta Ramni
- Gómez Coral Diego Mauricio
- Gómez Coral Diego Mauricio
- Gómez Ramírez Andrés
- Gómez Ramírez Andrés
- Görlich Lidia Maria
- Görlich Lidia Maria
- Gładysz-Dziaduś Ewa
- Gładysz-Dziaduś Ewa
- Haake Rüdiger
- Haake Rüdiger
- Haaland Øystein Senneset
- Haaland Øystein Senneset
- Hadjidakis Cynthia Marie
- Hadjidakis Cynthia Marie
- Haiduc Maria
- Haiduc Maria
- Haller Barthélémy von
- Haller Barthélémy von
- Hamagaki Hideki
- Hamagaki Hideki
- Hamar Gergö
- Hamar Gergö
- Harris John W.
- Harris John W.
- Harton Austin Vincent
- Harton Austin Vincent
- Hatzifotiadou Despina
- Hatzifotiadou Despina
- Hayashi Shinichi
- Hayashi Shinichi
- Heckel Stefan Thomas
- Heckel Stefan Thomas
- Heide Markus
- Heide Markus
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- Helstrup Håvard
- Herghelegiu Andrei Ionut
- Herghelegiu Andrei Ionut
- Herrera Corral Gerardo Antonio
- Herrera Corral Gerardo Antonio
- Hess Benjamin Andreas
- Hess Benjamin Andreas
- Hetland Kristin Fanebust
- Hetland Kristin Fanebust
- Hillemanns Hartmut
- Hillemanns Hartmut
- Hippolyte Boris
- Hippolyte Boris
- Hoorne Jacobus Willem van
- Hoorne Jacobus Willem van
- Hosokawa Ritsuya
- Hosokawa Ritsuya
- Hristov Peter
- Hristov Peter
- Huang M.
- Huang M.
- Humanic Thomas J.
- Humanic Thomas J.
- Hussain Nur
- Hussain Nur
- Hussain Tahir
- Hussain Tahir
- Hutter Dirk
- Hutter Dirk
- Hwang D.S.
- Hwang D.S.
- Ilkaev Radiy
- Ilkaev Radiy
- Inaba Motoi
- Inaba Motoi
- Ippolitov Mikhail
- Ippolitov Mikhail
- Irfan M.
- Irfan M.
- Ivanov Marian
- Ivanov Marian
- Ivanov V.
- Ivanov V.
- Izucheev Vladimir
- Izucheev Vladimir
- Jacobs Peter Martin
- Jacobs Peter Martin
- Jadhav Manoj Bhanudas
- Jadhav Manoj Bhanudas
- Jadlovska Slavka
- Jadlovska Slavka
- Jadlovsky Jan
- Jadlovsky Jan
- Jahnke Cristiane
- Jahnke Cristiane
- Jakubowska Monika Joanna
- Jakubowska Monika Joanna
- Jang Haeng Jin
- Jang Haeng Jin
- Janik Malgorzata Anna
- Janik Malgorzata Anna
- Jayarathna Pahula Hewage Sandun Yasassri
- Jayarathna Pahula Hewage Sandun Yasassri
- Jena Chitrasen
- Jena Chitrasen
- Jena Satyajit
- Jena Satyajit
- Jiménez Bustamante Raúl Tonatiuh
- Jiménez Bustamante Raúl Tonatiuh
- Jones Peter Graham
- Jones Peter Graham
- Jung H.
- Jung H.
- Jusko Anton
- Jusko Anton
- Kalinak Peter
- Kalinak Peter
- Kalweit Alexander Philipp
- Kalweit Alexander Philipp
- Kamin Jason Adrian
- Kamin Jason Adrian
- Kang Ju Hwan
- Kang Ju Hwan
- Kaplin Vladimir
- Kaplin Vladimir
- Kar Somnath
- Kar Somnath
- Karasu Uysal Ayben
- Karasu Uysal Ayben
- Karavichev Oleg V.
- Karavichev Oleg V.
- Karavicheva Tatiana L.
- Karavicheva Tatiana L.
- Karayan Lilit
- Karayan Lilit
- Karpechev Evgeny
- Karpechev Evgeny
- Kebschull Udo
- Kebschull Udo
- Keidel Ralf
- Keidel Ralf
- Keijdener Darius Laurens D.
- Keijdener Darius Laurens D.
- Keil Markus
- Keil Markus
- Khan P.
- Khan P.
- Khan Shuaib Ahmad
- Khan Shuaib Ahmad
- Khanzadeev Alexei
- Khanzadeev Alexei
- Kharlov Yury
- Kharlov Yury
- Kileng Bjarte
- Kileng Bjarte
- Kim D.
- Kim D.
- Kim D.J.
- Kim D.J.
- Kim D.W.
- Kim D.W.
- Kim H.
- Kim H.
- Kim J.S.
- Kim J.S.
- Kim M.
- Kim M.
- Kim M.
- Kim M.
- Kim S.
- Kim S.
- Kim T.
- Kim T.
- Kirsch Stefan
- Kirsch Stefan
- Kisel Ivan
- Kisel Ivan
- Kiselev Sergej N.
- Kiselev Sergej N.
- Kisiel Adam Ryszard
- Kisiel Adam Ryszard
- Kiss Gabor
- Kiss Gabor
- Klay Jennifer Lynn
- Klay Jennifer Lynn
- Klein Carsten
- Klein Carsten
- Klein Jochen
- Klein Jochen
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- Klewin Sebastian
- Klewin Sebastian
- Kluge Alexander
- Kluge Alexander
- Knichel Michael Linus
- Knichel Michael Linus
- Knospe Anders Garritt
- Knospe Anders Garritt
- Kobayashi Taiyo
- Kobayashi Taiyo
- Kobdaj Chinorat
- Kobdaj Chinorat
- Kollegger Thorsten
- Kollegger Thorsten
- Kolojvari Anatoly
- Kolojvari Anatoly
- Kondratiev Valery P.
- Kondratiev Valery P.
- Kondratyeva Natalia
- Kondratyeva Natalia
- Kondratyuk Evgeny
- Kondratyuk Evgeny
- Konevskikh Artem
- Konevskikh Artem
- Kopcik Michal
- Kopcik Michal
- Kour Mandeep
- Kour Mandeep
- Kouzinopoulos Charalampos
- Kouzinopoulos Charalampos
- Kovalenko Oleksandr
- Kovalenko Oleksandr
- Kovalenko Vladimir
- Kovalenko Vladimir
- Kowalski Marek
- Kowalski Marek
- Koyithatta Meethaleveedu Greeshma
- Koyithatta Meethaleveedu Greeshma
- Kravčáková Adela
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- Kretz Matthias
- Kretz Matthias
- Krivda Marian
- Krivda Marian
- Krizek Filip
- Krizek Filip
- Kryshen Evgeny
- Kryshen Evgeny
- Krzewicki Mikolaj
- Krzewicki Mikolaj
- Králik Ivan
- Králik Ivan
- Kubera Andrew Michael
- Kubera Andrew Michael
- Kuhn Christian Claude
- Kuhn Christian Claude
- Kuijer Paulus Gerardus
- Kuijer Paulus Gerardus
- Kumar Ajay
- Kumar Ajay
- Kumar Jitendra
- Kumar Jitendra
- Kumar Lokesh
- Kumar Lokesh
- Kumar Shyam
- Kumar Shyam
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- Kurashvili Podist
- Kurepin Alexander
- Kurepin Alexander
- Kurepin Alexey B.
- Kurepin Alexey B.
- Kuryakin Alexey
- Kuryakin Alexey
- Kučera Vít
- Kučera Vít
- Kweon Min Jung
- Kweon Min Jung
- Kwon Youngil
- Kwon Youngil
- La Pointe Sarah Louise
- La Pointe Sarah Louise
- La Rocca Paola
- La Rocca Paola
- Ladron de Guevara Pedro
- Ladron de Guevara Pedro
- Lagana Fernandes Caio
- Lagana Fernandes Caio
- Lakomov Igor
- Lakomov Igor
- Langoy Rune
- Langoy Rune
- Lara Martinez Camilo Ernesto
- Lara Martinez Camilo Ernesto
- Lardeux Antoine Xavier
- Lardeux Antoine Xavier
- Lattuca Alessandra
- Lattuca Alessandra
- Laudi Elisa
- Laudi Elisa
- Lea Ramona
- Lea Ramona
- Leardini Lucia
- Leardini Lucia
- Lee Graham Richard
- Lee Graham Richard
- Lee S.
- Lee S.
- Leeuwen Marco van
- Leeuwen Marco van
- Lehas Fatiha
- Lehas Fatiha
- Lemmon Roy Crawford
- Lemmon Roy Crawford
- Lenti Vito
- Lenti Vito
- Leogrande Emilia
- Leogrande Emilia
- Leoncino Marco
- Leoncino Marco
- León Monzón Ildefonso
- León Monzón Ildefonso
- León Vargas H.
- León Vargas H.
- Li S.
- Li S.
- Li X.
- Li X.
- Lien Jørgen André
- Lien Jørgen André
- Lietava Roman
- Lietava Roman
- Lindal Svein
- Lindal Svein
- Lindenstruth Volker
- Lindenstruth Volker
- Lippmann Christian
- Lippmann Christian
- Lisa Michael A.
- Lisa Michael A.
- Ljunggren Hans Martin
- Ljunggren Hans Martin
- Lodato Davide Francesco
- Lodato Davide Francesco
- Loginov Vitaly
- Loginov Vitaly
- Loizides Constantinos
- Loizides Constantinos
- Lopez Xavier Bernard
- Lopez Xavier Bernard
- Lowe Andrew John
- Lowe Andrew John
- Lunardon Marcello
- Lunardon Marcello
- Luparello Grazia
- Luparello Grazia
- Luz Pedro Hugo Ferreira Natal da
- Luz Pedro Hugo Ferreira Natal da
- Lévai Péter
- Lévai Péter
- López Torres Ernesto
- López Torres Ernesto
- Lønne Per-Ivar
- Lønne Per-Ivar
- Lüttig Philipp
- Lüttig Philipp
- Maarel Jasper van der
- Maarel Jasper van der
- Maevskaya Alla
- Maevskaya Alla
- Mager Magnus
- Mager Magnus
- Mahajan Sanjay
- Mahajan Sanjay
- Mahmood Sohail Musa
- Mahmood Sohail Musa
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- Maire Antonin
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- Majka Richard Daniel
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- Malaev Mikhail
- Maldonado Cervantes Ivonne Alicia
- Maldonado Cervantes Ivonne Alicia
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- Malinina Liudmila
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- Malzacher Peter
- Mal’Kevich Dmitry
- Mal’Kevich Dmitry
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- Mamonov Alexander
- Manko Vladislav
- Manko Vladislav
- Manso Franck
- Manso Franck
- Manzari Vito
- Manzari Vito
- Marchisone Massimiliano
- Marchisone Massimiliano
- Mareš Jiří
- Mareš Jiří
- Margagliotti Giacomo Vito
- Margagliotti Giacomo Vito
- Margotti Anselmo
- Margotti Anselmo
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- Margutti Jacopo
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- Markert Christina
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- Marquard Marco
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- Martin Blanco Javier
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- Martinez Pedreira Miguel
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- Martínez Hernández Mario Iván
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- Marín Ana
- Mas Alexis Jean-Michel
- Mas Alexis Jean-Michel
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- Masciocchi Silvia
- Masera Massimo
- Masera Massimo
- Masoni Alberto
- Masoni Alberto
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- Massacrier Laure Marie
- Mastroserio Annalisa
- Mastroserio Annalisa
- Matyja Adam Tomasz
- Matyja Adam Tomasz
- Mayer Christoph
- Mayer Christoph
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- Mazer Joel Anthony
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- Mazzoni Alessandra Maria
- Mcdonald Daniel
- Mcdonald Daniel
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- Meddi Franco
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- Melikyan Yury
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- Menchaca-Rocha Arturo Alejandro
- Meninno Elisa
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- Mercado Pérez Jorge
- Meres Michal
- Meres Michal
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- Miake Yasuo
- Mieskolainen Matti Mikael
- Mieskolainen Matti Mikael
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- Mikhaylov Konstantin
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- Mitu Ciprian Mihai
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- Miśkowiec Dariusz Czesław
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- Mohammadi Naghmeh
- Mohanty Bedangadas
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- Mohisin Khan Mohammed
- Mohisin Khan Mohammed
- Molnar Levente
- Molnar Levente
- Montaño Zetina Luis Manuel
- Montaño Zetina Luis Manuel
- Montes Prado Esther
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- Mudnic Eugen
- Mudnic Eugen
- Muhuri Sanjib
- Muhuri Sanjib
- Mukherjee Maitreyee
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- Mulligan James Declan
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- Munzer Robert Helmut
- Munzer Robert Helmut
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- Musinsky Jan
- Mühlheim Daniel
- Mühlheim Daniel
- Naik Bharati
- Naik Bharati
- Nair Rahul Ramachandran
- Nair Rahul Ramachandran
- Nandi Basanta Kumar
- Nandi Basanta Kumar
- Nania Rosario
- Nania Rosario
- Nappi Eugenio
- Nappi Eugenio
- Naru Muhammad Umair
- Naru Muhammad Umair
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- Nattrass Christine
- Nayak Kishora
- Nayak Kishora
- Nayak Tapan Kumar
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- Nellen Lukas
- Ng Fabian
- Ng Fabian
- Nicassio Maria
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- Niculescu Mihai
- Niculescu Mihai
- Niedziela J.
- Niedziela J.
- Nielsen Borge Svane
- Nielsen Borge Svane
- Nikolaev Sergey
- Nikolaev Sergey
- Nikulin Sergey
- Nikulin Sergey
- Nikulin Vladimir
- Nikulin Vladimir
- Noferini Francesco
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- Nomokonov Petr V.
- Nomokonov Petr V.
- Nooren Gerardus
- Nooren Gerardus
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- Nyanin Alexander
- Nyanin Alexander
- Nystrand Joakim Ingemar
- Nystrand Joakim Ingemar
- Oeschler Helmut
- Oeschler Helmut
- Oh S.
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- Oh Sun Kun
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- Okubo Tsubasa
- Okubo Tsubasa
- Oleniacz Janusz
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- Oliver Michael Henry
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- Onderwaater Jacobus
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- Ortiz Velasquez Antonio
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- Oskarsson Anders Nils Erik
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- Otwinowski Jacek Tomasz
- Oyama Ken
- Oyama Ken
- Pachmayer Yvonne C.
- Pachmayer Yvonne C.
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- Pagano Paola
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- Pal Susanta Kumar
- Pal Susanta Kumar
- Pan Jinjin
- Pan Jinjin
- Pandey Ashutosh Kumar
- Pandey Ashutosh Kumar
- Papcun P.
- Papcun P.
- Papikyan Vardanush
- Papikyan Vardanush
- Pappalardo Giuseppe Salvatore
- Pappalardo Giuseppe Salvatore
- Pareek Pooja
- Pareek Pooja
- Park WooJin
- Park WooJin
- Parmar Sonia
- Parmar Sonia
- Passfeld Annika
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- Paticchio Vincenzo
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- Patra Rajendra Nath
- Patra Rajendra Nath
- Paul Biswarup
- Paul Biswarup
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- Pereira da Costa Hugo Denis Antonio
- Pereira da Costa Hugo Denis Antonio
- Peresunko Dmitry Yurevich
- Peresunko Dmitry Yurevich
- Perez Moreno Luis Alberto
- Perez Moreno Luis Alberto
- Peskov Vladimir
- Peskov Vladimir
- Pestov Yury N.
- Pestov Yury N.
- Petrov Viacheslav
- Petrov Viacheslav
- Petrovici Mihai A.
- Petrovici Mihai A.
- Petráček Vojtech
- Petráček Vojtech
- Petta Catia
- Petta Catia
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- Pikna Miroslav
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- Pillot Philippe
- Pillot Philippe
- Pinazza Ombretta
- Pinazza Ombretta
- Pinsky Lawrence
- Pinsky Lawrence
- Piyarathna Danthasinghe B.
- Piyarathna Danthasinghe B.
- Planinic Mirko
- Planinic Mirko
- Pluta Jan Marian
- Pluta Jan Marian
- Pochybova Sona
- Pochybova Sona
- Podesta Lerma Pedro Luis Manuel
- Podesta Lerma Pedro Luis Manuel
- Poghosyan Martin G.
- Poghosyan Martin G.
- Polichtchouk Boris
- Polichtchouk Boris
- Poljak Nikola
- Poljak Nikola
- Poonsawat Wanchaloem
- Poonsawat Wanchaloem
- Pop Amalia
- Pop Amalia
- Porteboeuf-Houssais Sarah Julie
- Porteboeuf-Houssais Sarah Julie
- Porter Jeffrey Brent
- Porter Jeffrey Brent
- Pospisil Jan
- Pospisil Jan
- Prado Caio Alves Garcia
- Prado Caio Alves Garcia
- Prasad Sidharth Kumar
- Prasad Sidharth Kumar
- Preghenella Roberto
- Preghenella Roberto
- Prino Francesco
- Prino Francesco
- Pruneau Claude A.
- Pruneau Claude A.
- Pshenichnov Igor A.
- Pshenichnov Igor A.
- Puccio Maximiliano
- Puccio Maximiliano
- Puddu Giovanna
- Puddu Giovanna
- Pujahari Prabhat Ranjan
- Pujahari Prabhat Ranjan
- Punin Valery
- Punin Valery
- Putschke Jörn H.
- Putschke Jörn H.
- Pérez Lara Carlos Eugenio
- Pérez Lara Carlos Eugenio
- Pérez Lezama Edgar
- Pérez Lezama Edgar
- Płoskoń Mateusz
- Płoskoń Mateusz
- Qvigstad Henrik
- Qvigstad Henrik
- Rachevski Alexandre
- Rachevski Alexandre
- Raha Sibaji
- Raha Sibaji
- Rajput Sonia
- Rajput Sonia
- Rak Jan
- Rak Jan
- Rakotozafindrabe Andry Malala
- Rakotozafindrabe Andry Malala
- Ramello Luciano
- Ramello Luciano
- Rami Fouad
- Rami Fouad
- Raniwala Rashmi
- Raniwala Rashmi
- Raniwala Sudhir
- Raniwala Sudhir
- Rascanu Bogdan Theodor
- Rascanu Bogdan Theodor
- Rathee Deepika
- Rathee Deepika
- Read Kenneth Francis
- Read Kenneth Francis
- Redlich Krzysztof
- Redlich Krzysztof
- Reed Rosi Jan
- Reed Rosi Jan
- Rehman Attiq ur
- Rehman Attiq ur
- Reichelt Patrick
- Reichelt Patrick
- Reidt Felix
- Reidt Felix
- Ren Xiaowen
- Ren Xiaowen
- Renfordt Rainer Arno Ernst
- Renfordt Rainer Arno Ernst
- Reolon Anna Rita
- Reolon Anna Rita
- Reshetin Andrey
- Reshetin Andrey
- Revol Jean-Pierre
- Revol Jean-Pierre
- Reygers Klaus
- Reygers Klaus
- Riabov Viktor G.
- Riabov Viktor G.
- Ricci Renato Angelo
- Ricci Renato Angelo
- Richert Tuva Ora Herenui
- Richert Tuva Ora Herenui
- Richter Matthias Rudolph
- Richter Matthias Rudolph
- Riedler Petra
- Riedler Petra
- Riegler Werner
- Riegler Werner
- Riggi Francesco
- Riggi Francesco
- Ristea Cătălin-Lucian
- Ristea Cătălin-Lucian
- Rocco Elena
- Rocco Elena
- Rodriguez Manso Alis
- Rodriguez Manso Alis
- Rodrı́guez Cahuantzi Mario
- Rodrı́guez Cahuantzi Mario
- Rogochaya Elena
- Rogochaya Elena
- Rohr David
- Rohr David
- Romita Rosa
- Romita Rosa
- Ronchetti Federico
- Ronchetti Federico
- Ronflette Lucile
- Ronflette Lucile
- Rosnet Philippe
- Rosnet Philippe
- Rossi Andrea
- Rossi Andrea
- Roukoutakis Filimon
- Roukoutakis Filimon
- Roy Ankhi
- Roy Ankhi
- Roy Christelle Sophie
- Roy Christelle Sophie
- Roy Pradip Kumar
- Roy Pradip Kumar
- Rubio Montero Antonio Juan
- Rubio Montero Antonio Juan
- Rui Rinaldo
- Rui Rinaldo
- Russo R.
- Russo R.
- Ryabinkin Evgeny
- Ryabinkin Evgeny
- Ryabov Yury
- Ryabov Yury
- Rybicki Andrzej
- Rybicki Andrzej
- Räsänen Sami Sakari
- Räsänen Sami Sakari
- Röhrich Dieter
- Röhrich Dieter
- Røed Ketil
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- Wilkinson Jeremy
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- Yaldo C.G.
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- Yang Ping
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- Yano Satoshi
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- Yurchenko Volodymyr
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- Zbroszczyk Hanna Paulina
- Zbroszczyk Hanna Paulina
- Zgura Ion-Sorin
- Zgura Ion-Sorin
- Zhalov Mikhail
- Zhalov Mikhail
- Zhang C.
- Zhang C.
- Zhang H.
- Zhang H.
- Zhang X.
- Zhang X.
- Zhang Y.
- Zhang Y.
- Zhang Z.
- Zhang Z.
- Zhao C.
- Zhao C.
- Zhigareva Natalia
- Zhigareva Natalia
- Zhou D.
- Zhou D.
- Zhou Y.
- Zhou Y.
- Zhou Z.
- Zhou Z.
- Zhu H.
- Zhu H.
- Zhu J.
- Zhu J.
- Zichichi Antonino
- Zichichi Antonino
- Zimmermann Alice
- Zimmermann Alice
- Zimmermann Markus
- Zimmermann Markus
- Zinovjev Gennady M.
- Zinovjev Gennady M.
- Zyzak Maksym
- Zyzak Maksym
- Závada Petr
- Závada Petr
- Özdemir Mahmut
- Özdemir Mahmut
- Čepila Jan
- Čepila Jan
- Šafařík Karel
- Šafařík Karel
- Šefčík Michal
- Šefčík Michal
- Šuljić Miljenko
- Šuljić Miljenko
- Šumbera Michal
- Šumbera Michal
- Šándor Ladislav
- Šándor Ladislav
- Publication venue
- Publication date
- 14/09/2015
- Field of study
Peer reviewe
Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study
- Author
- A. Mohammed Kalakwa
- A. Nemer Ayoub
- Abantanga Francis A.
- Abatli Safa' Jamal
- Abbas Wisam
- Abbo Olivier
- Abdelbaqi Reem
- Abdelhady Dina Sobhy
- Abdelhafez Mohammad Omar Mohammad
- Abdelhamid Sultan S.
- Abdelmaksoud Sherif
- Abdelmoumen Roua
- Abdelmutalib Fakereldeen
- Abdul-Mumin Alhassan
- Abduljawad Fatima Mousa
- Abdullah Fizan
- Abdullah Mohd Yusof bin
- Abdulraheem Nurudeen
- Abdulrahman Alaa
- Abdulsalam Moruf Adekunle
- Abdunomonovich Dekhkonboev Avazjon
- Aboelela Ahmed
- Abouheba Mohamed
- Abrahamsson Kate
- Abrunhosa Matias Marcia
- Abu-Nejmah Fawzi
- Abuajaila Abdulsalam
- Abuattaya Adham Ashraf
- Abubakar Auwal M
- Abueideh Ahmad
- Abuhayyeh Husam Aldean
- Abuhlega Ma'aly A.
- Abukhalaf Sadi
- Abumunshar Ali Abdelhay
- Acuna Gaston
- Adams Stephen
- Adamu Sani
- Adanan Mohd Fitri Shukri bin Mohamed
- Adawi Ihda
- Adawi Samer
- Adawy Ahmad
- Ade-Ajayi Niyi
- Adegboyega Rilwan
- Ademuyiwa Adesoji
- Adesanya Opeoluwa
- Adhiwidjaja Cathline Freya
- Adofo-Ansong Nana
- Agboola Titiloye Hannah
- Agelebe Efeturi
- Aguilar Aguilar Faye
- Aguilar Gargurevich Prince Pamela
- Aguirre-Lopez Pastor
- Agulham Miguel Angelo
- Ahmad Hira
- Ahmad Zahidah Adlynee Haji
- Ahmed Hazem
- Ahmed Mahmoud Abdelfattah
- Ajai Olalekan Temitope
- Ajao Emmanuel Akinlabi
- Ajiboye Olalekan S.
- Ajrami Yara
- Ajwa Ahmad Elian Abu
- Akan M. Eren
- Akhbari Melika
- Akhter Nadeem
- Akova Fatih
- Al-Attar Hala M.
- Al-Halbouni Layana
- Al-Mamun Abdullah
- Al-Mayoof Ali Farooq
- Al-Momani Hashem M.
- Al-Mouakeh Ahmad
- Al-Rayyes Maisara
- Al-saleem Hasan Subhi Hasan Abu
- Al-Salhi Ashraf Ayman
- Al-Shwaikh Samar H.
- Al-Slaibi Ibrahim
- Al-Taher Raed Nael
- Al-Taher Raed Nael
- Al-Tammam Hiba
- Alakaloko Felix
- Alamrain Abdulwhhab Ayman Abu
- Alanguia Chipana Cathy Lee
- Alattas Khalid
- Alberto Carlos
- Albozidi Aya
- Alcántara Elvyn
- ALDIRAWI MOHAMMED A. M.
- Alebbini Mohanad Mutasem
- Alfoghi Mabroka
- Algabri Hayder Nadhim Obaid
- Alglaib Mohammed Meftah
- Alhamid Ahmad
- Alhamid Aos
- Alhassan Priscilla
- Ali Hassan
- Ali Karim Osamy
- Ali Liza
- Ali Mansour
- Alijla Sharif
- Alijla Sharif S.
- Aliwisat Ahmad Hasan
- Aljaboo Hajir
- Aljadidi Wesal Omar F. Saied
- Aljarad Ziad
- Alkareem Raghad mohammad abdu
- Almada Suad Ahmed
- Almadhoun Walaa
- Almasri Murad
- Almeida Aguiar Arthur
- Almeida Giovana
- Almengar Inas
- Almohamady Hisham
- Almosaibli Mohammad
- Almusleh Tasneem Fathi Hasan
- Alnaeri Ali
- Alnahhal Khaled
- Alonso Verónica
- Alosta Hasan Mustafa
- Alqarajeh Firas
- Alqor Mohammad Omar Ibrahim
- Alsaadi Nijmeh Nasser
- Alsaggaf Ameen
- Alsaied Amer
- Alser Mohammed
- Alser Osaid H.
- Alshaikhkhalil Haya Abdulnasser Ali
- Alshehri Abdullah
- Altaweel Ahmed
- Altın Merve
- Altokhais Tariq
- Altomi Mohamed
- Alturki Fahad
- Alvarado Zelada Jackelyne
- Alves Dutra da Silva Érika
- Alwadia Soha Marwan Salem
- Alwaggaa Nouriyah Ali
- Alzamari Ainaa Ata Mohammad
- Alzate Gallego Edgar
- Alzeer Asmahan Mohammad Suliman
- Alzerei Sulaiman T.
- Alzraikat Sayel H.
- Alzubair Afnan
- Alzughayyar Tareq Z.
- Amad Mohamed
- Amado Fernando
- Amaechi Chukwubinyelum
- Amah Christopher Chim
- Amarin Justin Z.
- Amarin Marzouq
- Ambriz-González Gabriela
- Ameh Emmanuel
- Amjad Muhammad Bin
- Amoabin Afua Amoabin
- Anatole Nzanzu
- Anatole Nzanzu Kipata
- Anaya Dominguez Marlene
- Anaya Firas
- Andrade Jerhy
- Andreussi Lorna
- Anicama Elias Rocio
- Annajjar Mohammad hasan
- Anntinea Jessmine
- Antunes Amanda
- Antunez-Mora Alexandra
- Anyomih Theophilus Teddy Kojo
- Anzelewicz Stefan
- Apaza Leon Jose Luis
- Appeadu-Mensah William
- Arabiat Esraa
- Arafa Mohamed Ahmed
- Arafat Hasan
- Aragão Liliana
- Arancibia Gutiérrez Elsa
- Aranda Sánchez Cristian Irela
- Arar Ahmad Samih
- Arauco Jenny
- Arbab Hana
- Arboleda Jenny
- Aremo Anuoluwapo
- Arnadóttir Helena
- Arnaud Alexis P
- Arnold Marion
- Arnoletto Lucia Beatriz
- Arrmali Saddam
- Arrmalli Lina Ali
- Arshad Muhammad
- Arthur Felicity
- Arul Suren
- Ashour Dina Ayman
- Ashour Yara shareef
- Aslan Yakup
- Aspirot Ann
- Assi Ahmadfateh
- Assi Muath Abdelrahem Fuad
- Astudillo Miguel
- Atatri Yazid yousef mahmoud
- Atta Ahmed
- Attia Alaa Mobarak
- Avile Romina
- Avolio Luigi
- Awad Hadeel
- Aydin Emrah
- Aykut Merve
- Ayque Rosas Fernando
- Aziz Dayang Anita Abdul
- Ba'baa' Basheer
- Badr Helmy
- Baertschiger Reto
- Bagbio Dominic
- Bah Abdoulie
- Bai Qiang
- Bai Yu Zuo
- Baistrocchi Valentina
- Bakar Ainal Huda Abu
- Baker Wisam
- Ballouhey Quentin
- Balousha Abrar ghassan
- Bamanga Ahmed
- Baniowda Muath A. M.
- Bao Xiaozhou
- Barauskas Vidmantas
- Barbosa Patricia Reis
- Baseggio Natalia
- Bashir Fatma
- Bashir Muhammad Kashif
- Bassan Gonçalves Paulo César
- Bataineh Ziad A.
- Batal Mohammad Mohannad
- Bazozi Hana Milad
- Beasley Spencer
- Becker Karin
- Belmino Gadelha Aluísio Augusto
- Benaskeur Yousra-Imane
- Beres Alana
- Berková Klára
- Bernaus Marianela
- Berrocal Anaya Waldo
- Berzanskis Mindaugas
- Beshtawi Doha mustafa saleh
- Beşir Ahmet
- Bianchin Ezequiel
- Bibas Fatma
- Biber Elna
- Bischoff Cristiano
- Bismarck Sylvester von
- Blain Otilia Eva
- Blanc Thomas
- Blazquez-Gomez Eva
- Bobadilla Morales Lucina
- Bode Christopher
- Bonnard Arnaud
- Boonthai Ampaipan
- Borbonet Daniel
- Bouhadiba Nordeen
- Bowder Alex
- Bracho Blanchet Eduardo
- Bradshaw Kate
- Bragagnini Paolo
- Brahmamdam Pavan
- Bravo Mauro Nicolas
- Bright Benedict Paul
- Brito Quevedo Luz Mery
- Broch Aline
- Brolin Santis Isolan Paola Maria
- Brunero Marco
- Bruxel Carla Luisa
- Bsisu Isam
- Bucaram Elena
- Bueno Mazzuca Rafael
- Bueno Motter Sarah
- Bujarimin Ahmad Shafiee bin
- Bulnes Mendizabal David
- Burks Stephen S.
- Burns Kate
- Butler Marilyn
- Bvulani Bruce
- C. Nwosu David
- Caamal Lorenzo Juvencio
- Calancea Calin
- Calderon Moore Antonio
- Calderón Arancibia José Alfredo
- Calistus Nwachukwu
- Cama Jitoko
- Camamra Kajali
- Cameron Fraser
- Camp Lauren
- Canözer Ali
- Caouette-Laberge Louise
- Cardenas Alva Loreley Raquel
- Cardenas Ruiz Velasco Juan Jose
- Carrasco Ana Lucia
- Carrasco-Ortega Cesar
- Carrillo Isabel
- Casado Francis Tanise
- Casal Beloy Isabel
- Caseb Paloma
- Casquero Victor
- Castañeda Espinosa Sergio
- Castaño Avila Daniela
- Castedo Camacho Fabiola Ruth
- Cavaiuolo Silvia
- Cañapataña Sahuanay Veronica Raquel
- Cepeda Rodrigo
- Cesur İlknur Banlı
- Chan Jonathan
- Chang Jeremy
- Charras Maria Delia
- Chaudary Ali Raza
- Chaudhry Muhammad Amjad
- Chauhan Nirav
- Chavez Galvez Patricia
- Chen Lulu
- Chen Rui
- Cheung Maija
- Chipalavela Rossana Francisco
- Chiriboga Elena
- Chitiavi Soita Wycliffe
- Chitnis Milind
- Cho Seok Hyeon
- Choo Candy SC
- Chukwu Isaac
- Chukwuemeka Anyanwu Lofty-John
- Chung Jae Hee
- Cletus Cyril
- Coghill Griffin
- Collins Nwokoro
- Colombo de Holanda Felipe
- Contreras Carla Sofia
- Coon John
- Cordonnier Annelien
- Cornelli Fabio
- Cornwall Hannah
- Corona C. Rivera Jorge Román
- Corona Rivera Alfredo
- Correa Leite Mila Torii
- Correa Armandou
- Correa Catalina
- Corrêa Costa Eduardo
- Cosoreanu Vlad
- Costas-Chavarri Ainhoa
- Cripovich Alejandrina
- Cunningham Aaron
- Czauderna Piotr
- Cáceres Aucatoma Freud
- Cárdenas Barón José de Jesús
- Cömert Hatice Sonay Yalçın
- da Silva Augusto Maria Lucia
- Dagilytė Rūta
- Dahman Nesrine Ben Hadj
- Dajia Wang
- Dalek Noor Fa'izatul Rahil Ambok
- Dallegre Maria Belen
- Dalloul Hisham
- Damiani Andrea
- Dammagh Nagham Mohammed Al
- Dania Bouguermouh
- Darras Osama Majed
- Darwish Ahmed S
- Darwish Ammar
- Dass Anthony
- Dassonville Martine
- Davenport Kate
- David Kuria
- Davies Justine
- Davis Jenna Kylene
- de Assis Silva Murilo
- de Azevedo Belesa Flavia
- de Campos Vieira Abib Simone
- de Deus Passos Leles Kamila
- de Guzman Johann
- de Souza Santos Ferreira Mariana
- Dedeke Florence
- Defago Victor Hugo
- Defert Coralie
- Delefortrie Thomas
- Delforge Xavier
- Delft Dirk von
- Delgado Malaga Florangel Patricia
- Delgado Quinteros Edgar Fernando
- Dellenmark Blom Michaela
- Dendusic Nejra
- Derbew Miliard
- Derks Terry
- Deya Corazone
- Deyab Abdelaziz
- Di Siervi Oscar
- Diaz Castañeda Flor de Maria
- Diaz Echegaray Marlene
- Diaz Gomez Jose Manuel
- Diaz Leon Cesar
- Dieudonné Lemfuka
- Dimatatac Doris Mae
- Djordjevic Ivona
- Dogar Sohail
- Doheim Mohamed Fahmy
- Dominguez Danny
- Donglai Hu
- Dornellas do Nascimento Suely
- dos Santos Dias André Iván Bradley
- Dosselman Luke J.
- Douiri Abdel
- Drah Weam
- Dube Andile Maqhawe
- Duchesne Camille
- Duggan Eileen
- Duote Cai
- Dure Carolina
- Dávila Perez Roberto
- Ebeido Annan
- Egbuchulem Ifeanyichukwu Kelvin
- Ejinkeonye Eze Chukwuemeka
- Ekenze Sebastian Okwuchukwu
- Ekwunife Okechukwu Hyginus
- El-Ghazaly Mohammed
- Elassall Gena Mohamed Hamed
- Elayeb Abdallah
- Elebute Olumide Abiodun
- Elewaily Mohamed
- Elfiky Mahmoud
- Elgammudi Mala
- Elghazaly Shrouk Mahmoud
- Elhadi Ahmed
- Elhadi Muhammed
- Elhajjaji Yasmine Ali
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- Wishah Nidal
- Wissanji Hussein
- Wolak Przemyslaw
- Wolny Agnieszka
- Wong Janice
- Wong Marilyn
- Wright Naomi Jane
- Wu Guowei
- Wyrzykowski Dariusz
- Xiaodong Guo
- Xie Hua
- Yacoub Mina A.
- Yaghi Bashar
- Yaghi Dua Hasan
- Yalcinkaya Ali
- Yang Hee-Beom
- Yanis Ahmad H.
- Yanowsky Reyes Guillermo
- Yao Yang
- Yapo Benjamin
- Yarza Fernández Jessica
- Yeniay Aslı Öztürk
- Yola Mariya Mukhtar
- Yong Feng
- Youn Joong Kee
- Yousuf Hina
- Yu Mengnan
- Yu Raisa
- Yuen Quah Soong
- Yuldashev Rustam Z.
- Yunus Aayenah
- Za'nouneh Faris J. Abu
- Zaghlol Louay Y.
- Zahari Dato' Dr Zakaria bin
- Zain Mostafa
- Zaman Azrina SK
- Zanellato Josiane Bernartt
- Zarwawi Ahmad Zulhisyam bin
- Zea-Salazar Luis Enrique
- Zeinelabdeen Ali
- Zhao Xiaoxia
- Zhu Jianming
- Zhu Libin
- Zidan Mazen
- Zivanovic Dragoljub
- Zottis Barcelos Fabricio
- Zreeg Dafer abdulhakim . S.
- Zurikat Rajai O.
- Zvizdic Nada
- Zvizdic Zlatan
- Çekiç Bahanur
- Çelik Müge
- Özçelik Zerrin
- Şeref Kıvanç
- Šafus Antonín
- Škvařil Jan
- Štichhauer Radek
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
Summary
Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally.
Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies
have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of
the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income
countries globally, and identified factors associated with mortality.
Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to
hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis,
exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a
minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical
status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary
intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause,
in-hospital mortality for all conditions combined and each condition individually, stratified by country income status.
We did a complete case analysis.
Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital
diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal
malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome
countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male.
Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3).
Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income
countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups).
Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome
countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries;
p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients
combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11],
p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20
[1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention
(ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety
checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed
(ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of
parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65
[0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality.
Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome,
middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will
be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger
than 5 years by 2030
How do women living with HIV experience menopause? Menopausal symptoms, anxiety and depression according to reproductive age in a multicenter cohort
- Author
- Abellán Javier Garcia
- Adsuar Araceli
- Agea Iván
- Aiello Francesco
- Alba Verónica
- Albendin Helena
- Alcaraz García Antonia
- Alcaraz Begoña
- Alcaraz Maria Jose
- Aldamiz-Echevarría Teresa
- Aldeguer José López
- Alejos Belén
- Alemán María Remedios
- Algado Rabasa José Tomás
- Alonso Marta Moreno
- Amador Concha
- Amengual Guedan Maria Jose
- Antela Antonio
- Anxa Urroz Usua
- Aramburu Maria José
- Arazo Piedad
- Arnalich Francisco
- Arranz Caso Alberto
- Arribas José Ramón
- Arrizabalaga Julio
- Asensi Victor
- Ayerdi Oskar
- Azkune Harkaitz
- Ballesteros Juan
- Balsalobre Pascual
- Baraia-Etxaburu Josu Mirena
- Barber Xavier
- Benito Concha
- Berenguer Juan
- Bermejo Laura
- Bernal Enrique
- Bisbal Otilia
- Blanco José Ramón
- Boix Vicente
- Bravo Urbieta Joaquín
- Busca Carmen
- Bustinduy Maria Jesús
- Cabello Alfonso
- Cairó Mireia
- Camacho Espejo Angela
- Camino Xabier
- Campins Antoni A
- Cano Sanchez Alfredo
- Cano Joanna
- Cardiñanos Julen
- Carmenado Maria Eugenia Rivas
- Carreres Melissa
- Carrió Juan Carlos
- Casado Osorio José Luis
- Castellanos Alfonso Javier
- Castro Iglesias Ángeles
- Castro Juan Miguel
- Cebrián Guadalupe Rúa
- Cervero Jiménez Miguel
- Chueca Natalia
- Colomé Joan Gregori
- Corma Gomez Anais
- Crespo Manuel
- Crestelo David Rial
- Curran Adrian
- Cámara López Maria Mar
- Dalmau David
- de Alda María Gracia Ruiz
- de Galarreta Beatriz Pierola Ruiz
- de la Peña Mireia
- de la Serna Jose Ignacio Bernardino
- de la torre Javier
- de León Cano María Teresa
- de los Santos Ignacio
- de Miguel Rosa
- de Quirós Juan Carlos López Bernaldo
- de Salazar Gonzalez Adolfo
- de Zarraga Miguel Alberto
- del Arco Alfonso
- del Campo Terrón Santos
- del Carmen Villalba Maria del Carmen
- del Mar Alonso María
- Del Romero Jorge
- Diez Cristina
- Domínguez Lourdes
- Díaz-Flores Felicitas
- Díez Marcos
- Ena Javier
- Escosa Luis
- Espinosa Nuria
- Estrada Pérez Vicente
- Fanciulli Chiara
- Fanjul Francisco
- Fenoll Vicenta
- Fernando Vilalta Ramón
- Fernández Fuertes Marta
- Fernández Irene Consuegra
- Fernández Marta
- Ferrer Ribera Ana
- Ferrero Beneitez Oscar Luis
- Font Roser
- Fraile Lucio Garcia-Fraile
- Frias Casas Mario
- Fuentes Lopez Ana
- Fuster Daniel
- Galera Carlos
- Galindo Puerto María José
- Garcia Manel Cervantes
- García de Lomas Guerrero José María
- García Dácil
- García Federico
- García Gema
- García Josefina
- García José Alberto
- García-Bujalance Silvia
- Gayo Enrique Martin
- Gijón Paloma
- Gil Anguita Concepción
- Gimeno Lina
- Giner Livia
- Goenaga Miguel Ángel
- Gonzalez-Domenec Carmen Maria
- Gonzalez-Serna Alejandro
- González Maria Isabel
- González-Baeza Alicia
- González-Garcia Juan
- González-Ruano Patricia
- Guerrero Beltrán Carlos
- Gutiérrez Carolina
- Gutiérrez Félix
- Gutiérrez Isabel
- Gómez Ayerbe Cristina
- Gómez Vidal María Amparo
- Gómez Juan Luis
- Górgolas Miguel
- Hernando Asunción
- Hernando Victoria
- Hernández Gutiérrez Cristina
- Hernández Iván Castro
- Hernández Jehovana
- Hernández María Inmaculada
- Herranz Pedro
- Hierro Ana Delgado
- Homar Francisco
- Hontañón Victor
- Ibarguren Maialen
- Ibarra Valvanera
- Iborra Asunción
- Igartua Maitane Umerez
- Imaz Arkaitz
- Iniesta Carlos
- Iribarren Jose Antonio
- Is Laura Pérez
- Isbert Sonia Calzado
- Jarrin Inma
- Jaén Ángels
- Jesús Téllez Molina Maria
- Jimeno Amaya
- Juliá Marino Blanes
- Kortajarena Xabier
- Latorre Leire Pérez
- Lirola Ana López
- Lizardi Aitzibir
- Lletí Miguel Salavert
- Lopez Azkarreta Iñigo
- Lopez Miriam
- Losada Elena
- López de Munain Josefina
- López López Pedro
- López Carmen Pérez
- López-Cortés Luis Fernando
- López-Dupla Miguel
- López-Hortelano Milagros García
- Machuca Sánchez Isabel
- Madrid Nadia
- Malmierca Eduardo
- Marcotegui Maria Riveiro
- Martin Maria Luisa
- Martinez Sanz Javier
- Martinez Marina
- Martinez-Lacasa Javier
- Martinez-Montes Clara
- Martín-Carbonero Maria Luz
- Martínez Lorena
- Martínez Onofre Juan
- Masiá Mar
- Mayoral Mario
- Meca Marisa
- Mellado Maria Jose
- Mena de Cea Álvaro
- Merchante Gutierrez Nicolás
- Merino Esperanza
- Merlos Maria Angustias
- Metola Luis
- Micán Rafael Esteban
- Miralles Celia
- Mohamed-Balghata Mohamed Omar
- Montejano Rocio
- Montes María Luisa
- Morano Luis
- Moreno Antonio
- Moreno Cristina
- Moreno Santiago
- Moreno Victoria
- Muga Roberto
- Murillas Javier
- Muñoz Fernández Maria Ángeles
- Muñoz Medina Leopoldo
- Muñoz Perez Ángeles
- Muñoz Eva Calabuig
- Muñoz Josefa
- Navarro Gemma
- Navarro Juan Fernández
- Navarro Maria Luisa
- Novella Mena Maria
- Nuñez Fernando Dronda
- Ocampo Antonio
- Olalla Sierra Julián
- Olona Montserrat
- Oteo José Antonio
- Oyaga Maria Pilar Carmona
- Padilla Belén
- Padilla Sergio
- Palacios Rosario
- Parras Francisco José
- Pascual Mario
- Pascual Rafael
- Pasquau Francisco
- Payeras Antoni
- Pelazas Ricardo
- Peraire Joaquin
- Perez Nieves Sanz
- Pernas Souto Berta
- Peñaranda María
- Pineda Juan A
- Pitarch Maria Tasias
- Podzamczer Daniel
- Portilla Irene
- Portilla Joaquín
- Pousada Guillermo
- Povedo Eva
- Prada José Luis
- Prieto Laura
- Prieto Paula
- Puerta Teresa
- Pulido Federico
- Pérez Elías María Jesús
- Pérez Stachowski Javier
- Pérez Alexandre
- Pérez Aurora
- Pérez Reyes Pascual
- Pérez-Elías Maria Jesús
- Pérez-Martínez Laura
- Pérez-Somarriba Moreno Juncal
- Pérez-Valero Ignacio
- Quero José Hernández
- Ramírez Margarita
- Raposo Utrilla Montserrat
- Rava Marta
- Re Vanessa Agullo
- Real Luis Miguel
- Repáraz Jesús
- Reus Sergio
- Ribas Maria Àngels
- Ribera Esteban
- Riera Melchor
- Rincón Mayo Pilar
- Rivero Juárez Antonio
- Rivero Román Antonio
- Robledano Catalina
- Roca Maria
- Rodrigo Dolores Martín
- Rodríguez Carmen
- Rodríguez Juan Carlos
- Rodríguez-Arrondo Francesc
- Rodríguez-Gallego Esther
- Rodés Berta
- Rubio Rafael
- Ruiz Seco Maria Pilar
- Rull Anna
- Sainz Talia
- Salas Aparicio Ana
- Sampériz Gloria
- Sanchez Juan Macías
- Sanmartí Montse
- Santacreu Mireia
- Santos Jesús
- Sanvisens Arantza
- Sanz Moreno José
- Sanz Sanz Jesús
- Sanz Mercedes
- Sarria Cepeda Cristina
- Saumoy Maria
- Secades Tomás Suárez Zarracina
- Sendagorta Elena
- Serrano Villar Sergio
- Silva Ana
- Sousa Luis Miguel García
- Suárez-García Ines
- Sánchez-Payá José
- Tasias María
- Tejerina Francisco
- Tiraboschi Juan
- Tomé Lidia Pascual
- Torres Perea Rafael
- Torrús Diego
- Tovar Sandra Cuéllar
- Ugarte Sofia Ibarra
- Universitat Autònoma de Barcelona. Departament de Medicina
- Valencia Eulalia
- Valle Eulalia
- Vargas Montserrat
- Velasco Tamara
- Velli Pablo
- Veloso Sergio
- Vera Francisco Jesús
- Vera Mar
- Vergas García Jorge
- Viciana Isabel
- Viciana Pompeyo
- Vidal Asunción
- Vidal Carmen
- Vidal Francesc
- Viladés Consuelo
- Vilasaro Marta Navarro
- Vilchez Helem H
- Vinuesa García David
- Vivancos Gallego Maria Jesús
- von Wichmann Miguel Ángel
- Zamora Ana Moreno
- Zuriñe Zubero Miren
- Álvarez Beatriz
- Álvarez Marta
- Publication venue
- Publication date
- 01/01/2021
- Field of study
CatedresBackground: To estimate the prevalence and severity of menopausal symptoms and anxiety/depression and to assess the differences according to menopausal status among women living with HIV aged 45-60 years from the cohort of Spanish HIV/AIDS Research Network (CoRIS). Methods: Women were interviewed by phone between September 2017 and December 2018 to determine whether they had experienced menopausal symptoms and anxiety/depression. The Menopause Rating Scale was used to evaluate the prevalence and severity of symptoms related to menopause in three subscales: somatic, psychologic and urogenital; and the 4-item Patient Health Questionnaire was used for anxiety/depression. Logistic regression models were used to estimate odds ratios (ORs) of association between menopausal status, and other potential risk factors, the presence and severity of somatic, psychological and urogenital symptoms and of anxiety/depression. Results: Of 251 women included, 137 (54.6%) were post-, 70 (27.9%) peri- and 44 (17.5%) pre-menopausal, respectively. Median age of onset menopause was 48 years (IQR 45-50). The proportions of pre-, peri- and post-menopausal women who had experienced any menopausal symptoms were 45.5%, 60.0% and 66.4%, respectively. Both peri- and post-menopause were associated with a higher likelihood of having somatic symptoms (aOR 3.01; 95% CI 1.38-6.55 and 2.63; 1.44-4.81, respectively), while post-menopause increased the likelihood of having psychological (2.16; 1.13-4.14) and urogenital symptoms (2.54; 1.42-4.85). By other hand, post-menopausal women had a statistically significant five-fold increase in the likelihood of presenting severe urogenital symptoms than pre-menopausal women (4.90; 1.74-13.84). No significant differences by menopausal status were found for anxiety/depression. Joint/muscle problems, exhaustion and sleeping disorders were the most commonly reported symptoms among all women. Differences in the prevalences of vaginal dryness (p = 0.002), joint/muscle complaints (p = 0.032), and sweating/flush (p = 0.032) were found among the three groups. Conclusions: Women living with HIV experienced a wide variety of menopausal symptoms, some of them initiated before women had any menstrual irregularity. We found a higher likelihood of somatic symptoms in peri- and post-menopausal women, while a higher likelihood of psychological and urogenital symptoms was found in post-menopausal women. Most somatic symptoms were of low or moderate severity, probably due to the good clinical and immunological situation of these women
COVID-19 in hospitalized HIV-positive and HIV-negative patients : A matched study
- Author
- Adsuar Araceli
- Agea Iván
- Aiello Francesco
- Alba Verónica
- Albendin Helena
- Alcaraz Begoña
- Alcaraz Maria Jose
- Alcaráz Antonia
- Aldamiz-Echevarría Teresa
- Alejos Belén
- Alemán María Remedios
- Algado José Tomás
- Alonso María del Mar
- Amador Concha
- Amengual María José
- Antela Antonio
- Anxa Urroz Usua
- Aramburu María José
- Arazo Piedad
- Arnalich Francisco
- Arranz Alberto
- Arribas José R.
- Arrizabalaga Julio
- Asensi Víctor
- Ayerdi Oskar
- Azkune Harkaitz
- Ballesteros Juan
- Balsalobre Pascual
- Baraia-Etxaburu Josu Mirena
- Barber Xavier
- Benito Concha
- Berenguer Juan
- Bermejo Laura
- Bernal Enrique
- Bernardino de la Serna, Jose Ignacio
- Bisbal Otilia
- Blanco José Ramón
- Blanes Marino
- Boix Vicente
- Bravo Urbieta Joaquín
- Busca Carmen
- Bustinduy Maria Jesús
- Cabello Alfonso
- Cairó Mireia
- Calabuig Eva
- Calzado Sonia
- Camacho Angela
- Camino Xabier
- Campins Antoni A.
- Cano Sanchez Alfredo
- Cano Joanna
- Cardiñanos Julen
- Carmona Oyaga Maria Pilar
- Carreres Melissa
- Carrió Juan Carlos
- Casado Jose Luis
- Castro Hernández Iván
- Castro Juan Miguel
- Castro Ángeles
- Cervantes Manel
- Cervero Miguel
- Chueca Natalia
- Colomé Joan Gregori
- Consuegra Fernández Irene
- Corma Gomez Anais
- Crespo Manuel
- Curran Adrian
- Cuéllar Sandra
- Cámara Maria Mar
- Dalmau David
- de la Peña Mireia
- de la Torre Javier
- de León Cano María Teresa
- de los Santos Ignacio
- de Miguel Rosa
- de Salazar Gonzalez Adolfo
- de Zarraga Miguel Alberto
- del Arco Alfonso
- del Campo Santos
- Del Romero-Raposo Jorge
- Delgado Hierro Ana
- Diez Cristina
- Diez Cristina
- Domínguez Lourdes
- Dronda Fernando
- Díaz-Flores Felicitas
- Díez Marcos
- Ena Javier
- Escosa Luis
- Espinosa Nuria
- Estrada Vicente
- Fanciulli Chiara
- Fanjul Francisco
- Fenoll Vicenta
- Fernández Fuertes Marta
- Fernández Navarro Juan
- Fernández Marta
- Ferrer Ana
- Ferrero Oscar Luis
- Font Roser
- Frias Mario
- Fuentes Ana
- Fuster Daniel
- Galera Carlos
- Galindo María José
- Garcia Abellán Javier
- Garcia-Fraile Lucio J.
- García de Lomas José María
- García López-Hortelano Milagros
- García Dácil
- García Federico
- García Federico
- García Gema
- García Josefina
- García José Alberto
- García-Bujalance Silvia
- Gijón Paloma
- Gil Anguita Concepción
- Gimeno Lina
- Giner Livia
- Goenaga Miguel Ángel
- Gonzalez-Domenec Carmen Maria
- Gonzalez-Serna Alejandro
- González Maria Isabel
- González-Baeza Alicia
- González-Garcia Juan
- González-Ruano Patricia
- Guerrero Carlos
- Gutiérrez Carolina
- Gutiérrez Félix
- Gutiérrez Isabel
- Gómez Ayerbe Cristina
- Gómez Vidal María Amparo
- Gómez-Sirvent Juan L.
- Górgolas Miguel
- Hernando Asunción
- Hernández Gutiérrez Cristina
- Hernández Quero José
- Hernández Jehovana
- Hernández María Inmaculada
- Herranz Pedro
- Homar Francisco
- Hontañón Víctor
- Ibarguren Maialen
- Ibarra Sofia
- Ibarra Valvanera
- Iborra Asunción
- Imaz Arkaitz
- Iniesta Carlos
- Iribarren Jose Antonio
- Iribarren José Antonio
- Izquierdo Rebeca
- Jarrin Inmaculada
- Jaén Angels
- Jimeno Amaya
- Kortajarena Xabier
- Latorre Leire Pérez
- Lizardi Aitziber
- Lopez Miriam
- Losada Elena
- López Azkarreta Iñigo
- López de Munain Josefina
- López Lirola Ana
- López Juan Carlos
- López Pedro
- López-Aldeguer José
- López-Cortés Luis Fernando
- Machuca Isabel
- Macías Juan
- Madrid Nadia
- Malmierca Eduardo
- Martin Maria Luisa
- Martinez Marina
- Martinez-Lacasa Javier
- Martinez-Montes Clara
- Martín Gayo Enrique
- Martín Rodrigo Dolores
- Martín-Carbonero Maria Luz
- Martínez Sanz Javier
- Martínez Lorena
- Martínez Onofre Juan
- Masip Jenifer
- Masiá Mar
- Mayoral Mario
- Meca Marisa
- Mellado Maria Jose
- Mena Álvaro
- Merchante Nicolás
- Merino Esperanza
- Merlos Maria Angustias
- Metola Luis
- Micán Rafael
- Miralles Celia
- Montejano Rocio
- Montero Marta
- Montes María Luisa
- Morano Luis
- Moreno Ana
- Moreno Antonio
- Moreno Cristina
- Moreno Santiago
- Moreno Victoria
- Muga Roberto
- Murillas Javier
- Muñoz Medina Leopoldo
- Muñoz Perez Ángeles
- Muñoz Josefa
- Muñoz-Fernández M Ángeles
- Navarro Vilasaro Marta
- Navarro Gemma
- Navarro Maria Luisa
- Novella María
- Ocampo Antonio
- Olalla Julian
- Olona Montserrat
- Omar Mohamed
- Oteo José Antonio
- Padilla Belén
- Padilla Sergio
- Palacios Rosario
- Parras Francisco José
- Pascual Pérez Reyes
- Pascual Tomé Lidia
- Pascual Rafael
- Pasquau Francisco
- Payeras Antoni
- Pelazas Ricardo
- Peraire Joaquín
- Pernas Berta
- Peñaranda María
- Pierola Beatriz
- Pineda Juan A
- Podzamczer Daniel
- Portilla Irene
- Portilla Joaquín
- Pousada Guillermo
- Poveda Eva
- Poveda Eva
- Prada José Luis
- Prieto Laura
- Prieto Paula
- Puerta Teresa
- Pulido Federico
- Pérez Elías Maria Jesús
- Pérez Is Laura
- Pérez López Carmen
- Pérez Stachowski Javier
- Pérez Alexandre
- Pérez Aurora
- Pérez-Martínez Laura
- Pérez-Somarriba Juncal
- Pérez-Valero Ignacio
- Ramírez Margarita
- Raposo Utrilla Montserrat
- Rava Marta
- Re Vanessa
- Real Luis Miguel
- Repáraz Jesús
- Reus Sergio
- Reverté Laia
- Rial David
- Ribas María Angels
- Ribera Esteban
- Riera Melchor
- Rincón Pilar
- Rivas Carmenado María Eugenia
- Rivero Juárez Antonio
- Rivero Marcotegui Maria
- Rivero Román Antonio
- Robledano Catalina
- Roca María
- Rodríguez Carmen
- Rodríguez Juan Carlos
- Rodríguez-Arrondo Francisco
- Rodés Berta
- Rubio Rafael
- Rubio Rafael
- Ruiz de Alda María Gracia
- Ruiz Seco Maria Pilar
- Rull Anna
- Rúa Cebrián Guadalupe
- Sainz Talia
- Salas Ana
- Salavert Lletí Miguel
- Sampériz Gloria
- Sanmartí Montse
- Santacreu Mireia
- Santos Jesús
- Sanvisens Arantza
- Sanz Moreno José
- Sanz Sanz Jesús
- Sanz Mercedes
- Sarriá Cristina
- Saumoy María
- Sendagorta Elena
- Serrano Sergio
- Silva Ana
- Suárez-García Inés
- Suárez-Zarracina Tomás
- Sánchez-Payá José
- Tasias Pitarch María
- Tejerina Francisco
- Tiraboschi Juan
- Torres Rafael
- Torrús Diego
- Téllez Maria Jesús
- Umerez Igartua Maitane
- Valencia Eulalia
- Valle Eulalia
- Vallejo Alejandro
- Vargas Montserrat
- Velasco Tamara
- Velli Pablo
- Veloso Sergio
- Vera Francisco J
- Vera Mar
- Vergas Jorge
- Viciana Isabel
- Viciana Pompeyo
- Vidal Asunción
- Vidal Carmen
- Vidal Francesc
- Vidal Francesc
- Viladés Consuelo
- Vilalta Ramon Fernando
- Vilchez Helem H.
- Villalba Maria del Carmen
- Vinuesa David
- Vivancos Maria Jesús
- von Wichmann Miguel Ángel
- Yeregui Elena
- Zubero Miren Zuriñe
- Álvarez Beatriz
- Álvarez Marta
- Publication venue
- Publication date
- 01/01/2021
- Field of study
CatedresObjectives: We compared the characteristics and clinical outcomes of hospitalized individuals with COVID-19 with [people with HIV (PWH)] and without (non-PWH) HIV co-infection in Spain during the first wave of the pandemic. Methods: This was a retrospective matched cohort study. People with HIV were identified by reviewing clinical records and laboratory registries of 10 922 patients in active-follow-up within the Spanish HIV Research Network (CoRIS) up to 30 June 2020. Each hospitalized PWH was matched with five non-PWH of the same age and sex randomly selected from COVID-19@Spain, a multicentre cohort of 4035 patients hospitalized with confirmed COVID-19. The main outcome was all-cause in-hospital mortality. Results: Forty-five PWH with PCR-confirmed COVID-19 were identified in CoRIS, 21 of whom were hospitalized. A total of 105 age/sex-matched controls were selected from the COVID-19@Spain cohort. The median age in both groups was 53 (Q1-Q3, 46-56) years, and 90.5% were men. In PWH, 19.1% were injecting drug users, 95.2% were on antiretroviral therapy, 94.4% had HIV-RNA < 50 copies/mL, and the median (Q1-Q3) CD4 count was 595 (349-798) cells/μL. No statistically significant differences were found between PWH and non-PWH in number of comorbidities, presenting signs and symptoms, laboratory parameters, radiology findings and severity scores on admission. Corticosteroids were administered to 33.3% and 27.4% of PWH and non-PWH, respectively (P = 0.580). Deaths during admission were documented in two (9.5%) PWH and 12 (11.4%) non-PWH (P = 0.800). Conclusions: Our findings suggest that well-controlled HIV infection does not modify the clinical presentation or worsen clinical outcomes of COVID-19 hospitalization
Association between administration of IL-6 antagonists and mortality among patients hospitalized for COVID-19 : a meta-analysis
- Author
- Abad-Santos Francisco
- Adegunsoye Ayodeji
- Al-Beidh Farah
- Aleman Soo
- ALMEIDA THIAGO M.L.
- Almuedo Alex
- Alonso Pérez Tamara
- Altice Frederick
- ANDRADE LUIS E.C.
- Angus Derek
- Annane Djillali
- Arabi Yaseen
- Arip Masita
- Asensi Victor
- Asgeirsson Hilmir
- Avendaño Solá Cristina
- AVEZUM ALVARO
- Axelrod Matthew
- AZEVEDO LUCIANO C.P.
- Azoulay Elie
- Baillie J Kenneth
- Baillie Kenneth J
- Baron Gabriel
- Barrios Ana
- Basri Sazali
- Bautista-Hernández Azucena
- Beane Abigail
- Beasley Richard
- Benbenishty Julie S.
- Bensaci Ana Maria
- Berry Lindsay
- Berry Lindsay R.
- Berry Scott
- BERWANGER OTÁVIO
- Bhimani Zahra
- Bidin Farah Nadiah
- Blennow Ola
- Bonten Marc
- Bosteels Cedric
- Bradbury Charlotte
- Broman Niklas
- Brunkhorst Frank
- Buch Maya H
- Bureau Serge
- Buxton Meredith
- Cadranel Jacques
- Campos Esteban José
- Carbonell Cristina
- CARCEL SHEILA
- CARVALHO JULIO CESAR
- CASTRO CLAUDIO G.
- Castro Pedro
- Castán Clara
- CAVALCANTI ALEXANDRE B.
- Cavalcanti Alexandre Biasi
- Chappell Lucy C
- Chatzidionysiou Katerina
- Cheng Allen
- Chidambaram Suresh
- Chong Meng Li
- Chun Geok Ying
- COELHO JULIANA C.
- Colman Roos
- CONCEIÇÃO FABIO G.
- Cooper Nichola
- Corbacho Noemí
- COSTA ANDRÉ N.
- Cove Matt
- Dalmau David
- DAMIANI LUCAS P.
- Day Jeremy N
- de Benito Natividad
- De Buyser Stefanie
- De Jong Menno
- De Leeuw Elisabeth
- DE SOUZA DENISE
- Declercq Jozefien
- Derde Lennie
- Derde Lennie P. G.
- Diaz Janet V.
- Domingo Pere
- Domingo Pere
- Dougados Maxime
- DOURADO LETICIA K.
- Emmerich Joseph
- Espinosa Gerard
- Estcourt Lise
- Estrada Vicente
- FARIAS DANIELLE L.C.
- Fartoukh Muriel
- Faust Saul N
- Fernandes Ana
- Fernandez-Cruz Ana
- Feuth Thijs
- Fisher David
- Fleisher Jorge
- Fortun Jesús
- Foulkes Andrea S
- Fowler Robert
- FREITAS FLAVIO G.R.
- Frigault Matthew J
- Galea James
- Galun Eitan
- Garcia Felipe
- Garcia-Vicuna Rosario
- García-Fraile Lucio
- GARRIDO JOSE CARLOS
- GEBARA OTAVIO C.E.
- Godolphin Peter J.
- Gonzalez-Alvaro Isidoro
- Goossens Herman
- Gordon Anthony
- Gordon Anthony C.
- Green Cameron
- Guidet Bertrand
- Gutierrez Felix
- Gutierrez Maria del Mar
- Gutiérrez Liarte Ángela
- Halid Luqman Alhakim
- Haniffa Rashan
- Harvey Liam
- Hasan Mohd Shahnaz
- Haynes Richard
- Haynes Richard
- Healy Brian C
- Henter Jan-Inge
- Hermine Olivier
- Hermine Olivier
- Herrera Silvia
- Higgins Alisa
- Higgins Julian P. T.
- Hills Thomas
- Hohenthal Ulla
- Horby Peter W
- Horby Peter W.
- Horcajada Juan Pablo
- Horick Nora K.
- Horne Anna Carin
- Huckins David S.
- Humbert Marc
- Ibrahim Nur Munirah
- Ichihara Nao
- ISHIHARA LUCIANA M.
- Jaki Thomas
- Janols Helena
- Jeffery Katie
- Juszczak Edmund
- Kamarulzaman Adeeba
- Karrison Theodore
- King Andrew
- Koh Hui Moon
- Kukreja Anjanna
- Kumar Kuldeep
- Lacombe Karine
- Lambrecht Bart
- Lamontagne Francois
- Lampa Jon
- Landray Martin J
- Landray Martin J.
- Lawler Patrick
- Leal Lorna
- Lederer David J.
- Lee Cheng Siang
- LEITE RODRIGO T.
- Leon Rafael
- LEON RAFAEL
- Lim Wei Shen
- Lin Nina
- LISBOA THIAGO C.
- Litton Ed
- LOPES RENATO D.
- Lorenzi Elizabeth
- Lorenzi Elizabeth
- MACHADO DAVID J.B.
- MACHADO FLAVIA R.
- Maes Bastiaan
- Mafham Marion
- Mahevas Matthieu
- Malinis Maricar
- Malouf Jorge
- Mansour Michael K
- Mariette Xavier
- Mariette Xavier
- Marshall John
- Marshall John C.
- MARTIN JOSIANE
- Marttila Harri
- Martínez José Antonio
- Mateo Gracia María
- McArthur Colin
- McAuley Daniel
- McGuinness Shay
- McVerry Bryan
- Megat Johari Bushra
- Mejía-Abril Gina
- MERCHANTE NICOLAS
- Merchante Nicolas
- Millan Lucia
- Misnan Nor Arisah
- Misnan Nor Arisah
- Mohamed Gani Yasmin
- Mohan Shalini V.
- Mohd Abd Rahim Mohd Abd Hafiz
- Mohd Thabit Alif Adlan
- Molas Maria Ema
- Montgomery Alan
- Montgommery Stephanie
- Morpeth Susan
- Mouncey Paul
- Mukri Mohd Noor Azreet
- Mumford Andrew
- Mur Isabel
- Murthy Srinivas
- Murthy Srinivas
- Muñez Rubio Elena
- Muñoz Jessica
- Muñóz José
- Neelamegam Malinee
- Netea Mihai
- Ng Rong Xiang
- Nichol Alistair
- Nikiforow Sarah
- Nivens Michael C.
- Niward Katarina F
- Nordberg Marika
- Nowak Piotr
- Ogungbenro Kayode
- Oksi Jarmo
- Omar Sharifah Faridah
- Ong Hang Cheng
- PACHECO EDUARDO S.
- Pacheco Iván
- Paredes Roger
- Parke Rachael
- Parke Åsa
- Parker Jane
- Patel Naomi J
- Pene Frédéric
- Perez-Molina Jose A
- Perez-Molina Jose A.
- Pettila Ville
- Pincus Michael D
- PINTÃO MARIA CAROLINA T.
- Pisano Jennifer
- Pizov Reuven
- Pizov Reuven
- Pomar Virginia
- Ponnampalavanar Sasheela
- Porcher Raphael
- Porcher Raphael
- Postma Simone
- Pourchet-Martinez Valérie
- PRATS JOÃO G.
- Price Christina
- Prieto Jose Carlos
- Prieto Sergio
- Raja Azwa Raja Iskandar Syah
- Raja Sureja Letchumi
- Rajasuriar Reena
- Rajasuriar Reena
- Ramanan Athimalaipet V.
- Ramos Martínez Antonio
- Rasmuson Johan
- Ratain Mark
- Ravaud Philippe
- Ravaud Philippe
- Reid Pankti D.
- Resche Rigon Matthieu
- Reyes Felipe
- Rodríguez-García Sebastian C
- ROJAS SALOMÓN S.O.
- ROSA REGIS G.
- Rosas Ivan O.
- Rowan Kathryn
- Ruiz-Antorán Belén
- Rutgers Abraham
- Sagar Manish
- Saito Hiroki
- Salama Carlos
- Sancho-Lopez Aranzazu
- SANDES ALEX R.
- Santos Marlene
- SANTOS SUELI V.
- Sanz Sanz Jesus
- Saravanamuttu Sujana
- Savovic Jelena
- SCHEINBERG PHILLIP
- Schlemmer Frédéric
- SCHNEIDER DANIEL
- Seto Todd B.
- Seymour Chris
- Shah Ruta
- Shankar-Hari Manu
- Shankar-Hari Manu
- Shrager Harry
- Sim Benedict
- SIQUEIRA SUELLEN R.R.
- Sivapalasingam Sumathi
- Skorup Paul
- Soin Arvinder Singh
- Soriano Alex
- Spiga Francesca
- Staplin Natalie
- Sterne Jonathan A. C.
- Stone John H.
- Strek Mary
- Strohbehn Garth W.
- Sulaiman Helmi
- Sunden-Cullberg Jonas
- Svensson Anna-Karin
- Syed Badaruddin Syarifah Nurul Ain
- Syed Mansor Syed Mukhtar
- Syed Omar Sharifah Faridah
- Sönnerborg Anders
- Tan Kok Tong
- Tay Kim Heng
- Thangavelu Suvintheran
- Tharaux Pierre Louis
- The WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group [missing]
- Thwaites Guy
- Tibi Annick
- Tierney Jayne
- Tong Steve
- TORRE-CISNEROS JULIAN
- Torre-Cisneros Julian
- Torres Ferran
- Tsai Larry W.
- Tuang Wei Xuan
- Turgeon Alexis
- Turner Anne
- Uyeki Tim
- Vale Claire L.
- Valtonen Mika
- van Bentum-Puijk Wilma
- Van Damme Karel
- van de Veerdonk Frank
- van Hoogstraten Hubert
- van Meerten Tom
- VEIGA VIVIANE C.
- Veiga Viviane Cordeiro
- Vesterbacka Jan C.
- Villar Luisa M
- Vuorinen Tytti
- Webb Steve
- Westerweel Peter E.
- Wong Chee Kuan
- Wong Pui Li
- Woolley Ann E.
- Yazdanpanah Yazdan
- Youngstein Taryn
- ZAMPIERI FERNANDO G.
- Zarychanski Ryan
- Zulhaimi Nurul Syuhada
- Publication venue
- 'American Medical Association (AMA)'
- Publication date
- 01/01/2021
- Field of study
IMPORTANCE Clinical trials assessing the efficacy of IL-6 antagonists in patients hospitalized for COVID-19 have variously reported benefit, no effect, and harm.
OBJECTIVE To estimate the association between administration of IL-6 antagonists compared with usual care or placebo and 28-day all-cause mortality and other outcomes.
DATA SOURCES Trials were identified through systematic searches of electronic databases between October 2020 and January 2021. Searches were not restricted by trial status or language. Additional trials were identified through contact with experts.
STUDY SELECTION Eligible trials randomly assigned patients hospitalized for COVID-19 to a group in whom IL-6 antagonists were administered and to a group in whom neither IL-6 antagonists nor any other immunomodulators except corticosteroids were administered. Among 72 potentially eligible trials, 27 (37.5%) met study selection criteria.
DATA EXTRACTION AND SYNTHESIS In this prospectivemeta-analysis, risk of biaswas assessed using the Cochrane Risk of Bias Assessment Tool. Inconsistency among trial results was assessed using the I-2 statistic. The primary analysis was an inverse variance-weighted fixed-effects meta-analysis of odds ratios (ORs) for 28-day all-cause mortality.
MAIN OUTCOMES AND MEASURES The primary outcome measurewas all-cause mortality at 28 days after randomization. There were 9 secondary outcomes including progression to invasive mechanical ventilation or death and risk of secondary infection by 28 days.
RESULTS A total of 10 930 patients (median age, 61 years [range of medians, 52-68 years]; 3560 [33%] were women) participating in 27 trials were included. By 28 days, there were 1407 deaths among 6449 patients randomized to IL-6 antagonists and 1158 deaths among 4481 patients randomized to usual care or placebo (summary OR, 0.86 [95% CI, 0.79-0.95]; P =.003 based on a fixed-effects meta-analysis). This corresponds to an absolute mortality risk of 22% for IL-6 antagonists compared with an assumed mortality risk of 25% for usual care or placebo. The corresponding summary ORs were 0.83 (95% CI, 0.74-0.92; P <.001) for tocilizumab and 1.08 (95% CI, 0.86-1.36; P =.52) for sarilumab. The summary ORs for the association with mortality compared with usual care or placebo in those receiving corticosteroids were 0.77 (95% CI, 0.68-0.87) for tocilizumab and 0.92 (95% CI, 0.61-1.38) for sarilumab. The ORs for the association with progression to invasive mechanical ventilation or death, compared with usual care or placebo, were 0.77 (95% CI, 0.70-0.85) for all IL-6 antagonists, 0.74 (95% CI, 0.66-0.82) for tocilizumab, and 1.00 (95% CI, 0.74-1.34) for sarilumab. Secondary infections by 28 days occurred in 21.9% of patients treated with IL-6 antagonists vs 17.6% of patients treated with usual care or placebo (OR accounting for trial sample sizes, 0.99; 95% CI, 0.85-1.16).
CONCLUSIONS AND RELEVANCE In this prospectivemeta-analysis of clinical trials of patients hospitalized for COVID-19, administration of IL-6 antagonists, compared with usual care or placebo, was associated with lower 28-day all-cause mortality
Global variations in heart failure etiology, management, and outcomes
- Author
- Abah Joseph P.
- Abang Serah M.
- Abdullakutty Jabir
- Abib Eduardo
- Acar Deniz R.
- Adler Frederic
- Ai Fen
- Airhart Sophia
- Al Mulla Arif Abudullatif
- Alasmari Sami
- Alghalayini Kamal
- AlHabib Khalid F.
- Alla François
- Anderson Kim
- Andrade Aurora
- Andriyevska Svitlana
- Ansa Victor
- Anzules Nicholas
- Arden Christopher
- Arimie Raluca
- Asotra Sanjeev
- Avezum Alvaro
- Bai Xioajuan
- Balasubramanian Kumar
- Ban'Haka Herve M.
- Barasa Felix
- Barton John
- Bayés-Genís Antoni
- Bazan Silmeia Z.
- Bazargani Nooshin
- Bednarski Janusz
- Bhatta Yadav
- Bobadilla Braulio
- Bott Michael C
- Boulestreav Romain
- Branch Kelley R.
- Bruder Oliver
- Budaj Andrzej
- Buelvas Jannes
- Buitrago Andres
- Caballero Eduardo B.
- Cadena Bonfanti Alberto
- Carrasco Santiago
- Carreno Erika M. M.
- Castro-Montes Eliodoro
- Cavusoglu Yuksel
- Celik Ahmet
- Ceron Juan A.
- Cetin Hande E. O.
- Chandra Sharad
- Chaudley Gaurav
- Chen XiaoPing
- Chen Yunguo
- Chillo Pilly
- Chmielinski Arkadiusz
- Clausell Nadine
- Clovis Nkoke
- Colette Sih
- Cosmi Franco
- Cruz Josefina
- Cursack Guillermo
- Cymerman Krzysztof
- Czerski Tomasz
- D'Orazio Simona
- Dada Fredy A. T.
- Damasceno Albertino
- Dans Antonio L.
- De La Espriella Rafael
- De Salazar Dora I. M.
- De Souza Weimar K. S. B.
- Delarche Nicolas
- Dokainish Hisham
- Donnelly Patrick
- Drexler Michael
- Duarte Yan C.
- Duma Neema
- Duran Ruben G.
- Dutra Oscar P.
- Dzudie Anastase
- Edwards Tim
- Eljach Julian E. V.
- ElSayed Ahmed
- Ertl Georg
- Evangelista Lauren K.
- Ezekowitz Justin
- Fedorov Sergiy
- Feuzeu Stachys A. N.
- Floderer Nagy Z
- Floras John
- Fomekong Tchinda G.
- Fox Keith
- Frisinghelli Anna
- Fuat Ahmet
- Gafarov Valery
- Gaggin Hanna
- Gao Xia
- Garcia Angel
- Garrido Bravo Iris
- Gislason Gunnar
- Gniot Jacek
- Goloskokova Valentina
- Gopalan Radha
- Gosse Philippe
- Gou Jian W.
- Goussot Samuel
- Grinvalds Alex
- Guillot Jean Paul
- Gulati Martha
- Gulec Sadi
- Gulizia Michele
- Gupta Rajeev
- Gómez-Mesa Juan Esteban
- Habeeb Waleed
- Hage Camilla
- Hagenow Andreas
- Hamou Kamel H.
- Heckman George
- Hernandes Mauro E.
- Hertting Klaus
- Hintze Rene
- Hominal Miguel A.
- Isakova Svetlana
- Ito Wulf
- Ivan Shvedov
- Jano Gabriel
- Jaramillo Milton S.
- Jathappa Narendra
- Jhund Pardeep
- Jia Zhisheng
- Jiang Heng
- Jin Wei
- Joseph Philip
- Jourda Francois
- Juneman Elizabeth
- Jungmair Wolfgang
- Kadel Christoph
- Kalokola Fredrick
- Kanenda Said
- Karaye Kamilu
- Karna Sunil
- Kassim Yasser
- Kataraihya Johannes
- Kayani Azhar M.
- Kazmi Khawar
- Kenizou David
- Khetan Aditya
- Kinsara Abdulhalim
- Kisenge Peter
- Kitchen Timothy
- Korol Marek
- Kostis John
- Kouam Charles K.
- Kovalkova Natalia
- Kragholm Kristian
- Lanas Fernando
- Lawand Samih
- Leong Darryl
- Lepage Serge
- Liang Tao
- Liang Xue W.
- Lindholm Carl-Johan
- Long Freddy P. C.
- Lonn Eva
- Lopez Jose A. C.
- Lopez José
- Lozada Henry G.
- Lugero Charles
- Lund Lars H.
- Luo Hai Y.
- López-Jaramillo Patricio
- Lönnberg Ingemar
- MacKinnon Ignacio
- Maggioni Aldo Pietro
- Mahrholdt Heiko
- Maia Lilia N.
- Maier Sebastian
- Makubi Abel
- Malhotra Vinay
- Manon Guillaume E.
- Marcassa Claudio
- Maurice Kristen
- Mbugua Evelyn
- Mcadam Brendan
- McCready Tara
- McKelvie Robert
- McMurray John J.V.
- Meda John R.
- Mehta Rajendra
- Meier Mark A.
- Mendoza Jose L. A.
- Mielniczuk Lisa
- Miklaszewicz Beata
- Minan Gema
- Minelli César
- Mirek-Bryniarska Ewa
- Moccetti Tiziano
- Moe Gordon
- Moeketsi Khulile
- Mohan Bishav
- Mondo Charles
- Monem Salwa
- Morales Dante
- Moreira Ilidio
- Moreno Gustavo S.
- Moriarty Andrew
- Mphahlele Makgotsane J.
- Murillo Nelson
- Murphy Andrew
- Murthy Sandhya
- Mwakalukwa Benson
- Mwita Julius Chacha
- Nagele Herbert
- Nalwa Wafula
- Ndjebet Jules
- Negi Parkash
- Nganou-Gnindjio Chris N.
- Ngongang Florent A. D.
- Nielsen Gitte
- Nobre Fernando
- Ntsekhe Mpiko
- Nyanga Albert
- Ogah Okechukwu
- Oliveira Lívia
- Oliveira Múcio
- Orlandini Andres
- Osipova Irina
- Owsiak Michal
- O’Donnell Martin
- Paniagua Martin Maria J.
- Panov Dmitry
- Parkhomenko Alexander
- Pavanello Ricardo
- Pedersen Maria
- Peng Jie
- Perez Francisco
- Piccinni Giancarlo
- Piepiorka Marek
- Piepoli Massimo
- Piña Illeana
- Pogosova Nana
- Poponina Tatiana
- Pozdnyakov Yury
- Prado Aldo
- Probstfield Jeffrey
- Qin Shaoming
- Quiroz Franklin
- Racine Normand
- Rasmussen Mariela
- Ratsela Andrew
- Reis Gilmar
- Rojas David G.
- Roses Josep L.
- Ross Heather
- Rouleau Jean-Lucien
- Roy Ambuj
- Russo Giulia
- Saidu Hadiza
- Salbieva Anzhela
- Sandoval Jorge
- Santiago Evelyn
- Schellong Sebastian
- Scopigni Francesca
- Senechal Mario
- Sergey Zabashta
- Sharma Deewakar
- Sharma Sanjib Kumar
- Sia Ying T.
- Silva-Cardoso José
- Sizova Zhanna
- Skorski Marcin
- Sliwa Karen
- Smith Stuart
- Sogaard Peter
- Solkiewicz Monika
- Sousa Antonio
- Stahl Fabian
- Stasiwski Arkadiusz
- Stoerk Thomas
- Störk Stefan
- Sudnik Wanda
- Sulit Dennis
- Sweitzer Nancy
- Swiggum Elizabeth
- Tamdja Anastase D.
- Tan Gange
- Tan Huiqiong
- Tantchou Cabral
- Tartiere Jean Michel
- Temizhan Ahmet
- Thew Stephen
- Thomas Baby M.
- Thorvaldsen Tonje
- Thulin Jorgen
- Tirador Louie
- Toma Mustafa
- Tournoux Francois
- Trujillo Freddy
- Ullah Jan Ubaid
- Varghese Kiron
- Vega Mario
- Velez Mayra S.
- Venturi Flavio
- Vereschuk Larysa
- Vilamajo Oscar G.
- Villani Giovanni Q
- Vogt Rainer
- Voronkov Leonid
- Wagdy Shaker Kerolos
- Wang Tianxun
- Wang Xiuhong
- Wei Fang
- Weiss Christian
- Whellan David
- Wiggers Henrik
- Witherow Fraser
- Wittlinger Thomas
- Wolf Alexander
- Wu Jijin
- Wujkowski Marek
- Xu Jing
- Yilmaz Mehmet B.
- Yonga Gerald
- Yufereva Yulia
- Yusubova Anara
- Yusuf Salim
- Zaidman Cesar J.
- Zalizna Yulia
- Zapata Gerardo
- Zeyad Mohamed
- Zheng Tinlin
- Zhou Wenxiu
- Zhu Jun
- Zieroth Shelley
- Zuelta Iván
- Publication venue
- 'American Medical Association (AMA)'
- Publication date
- 16/05/2023
- Field of study
Importance: Most epidemiological studies of heart failure (HF) have been conducted in high-income countries with limited comparable data from middle- or low-income countries.
Objective: To examine differences in HF etiology, treatment, and outcomes between groups of countries at different levels of economic development.
Design, Setting, and Participants: Multinational HF registry of 23 341 participants in 40 high-income, upper–middle-income, lower–middle-income, and low-income countries, followed up for a median period of 2.0 years.
Main Outcomes and Measures: HF cause, HF medication use, hospitalization, and death.
Results: Mean (SD) age of participants was 63.1 (14.9) years, and 9119 (39.1%) were female. The most common cause of HF was ischemic heart disease (38.1%) followed by hypertension (20.2%). The proportion of participants with HF with reduced ejection fraction taking the combination of a β-blocker, renin-angiotensin system inhibitor, and mineralocorticoid receptor antagonist was highest in upper–middle-income (61.9%) and high-income countries (51.1%), and it was lowest in low-income (45.7%) and lower–middle-income countries (39.5%) (P < .001). The age- and sex- standardized mortality rate per 100 person-years was lowest in high-income countries (7.8 [95% CI, 7.5-8.2]), 9.3 (95% CI, 8.8-9.9) in upper–middle-income countries, 15.7 (95% CI, 15.0-16.4) in lower–middle-income countries, and it was highest in low-income countries (19.1 [95% CI, 17.6-20.7]). Hospitalization rates were more frequent than death rates in high-income countries (ratio = 3.8) and in upper–middle-income countries (ratio = 2.4), similar in lower–middle-income countries (ratio = 1.1), and less frequent in low-income countries (ratio = 0.6). The 30-day case-fatality rate after first hospital admission was lowest in high-income countries (6.7%), followed by upper–middle-income countries (9.7%), then lower–middle-income countries (21.1%), and highest in low-income countries (31.6%). The proportional risk of death within 30 days of a first hospital admission was 3- to 5-fold higher in lower–middle-income countries and low-income countries compared with high-income countries after adjusting for patient characteristics and use of long-term HF therapies.
Conclusions and Relevance: This study of HF patients from 40 different countries and derived from 4 different economic levels demonstrated differences in HF etiologies, management, and outcomes. These data may be useful in planning approaches to improve HF prevention and treatment globally
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