170 research outputs found
Adaptive optics in high-contrast imaging
The development of adaptive optics (AO) played a major role in modern
astronomy over the last three decades. By compensating for the atmospheric
turbulence, these systems enable to reach the diffraction limit on large
telescopes. In this review, we will focus on high contrast applications of
adaptive optics, namely, imaging the close vicinity of bright stellar objects
and revealing regions otherwise hidden within the turbulent halo of the
atmosphere to look for objects with a contrast ratio lower than 10^-4 with
respect to the central star. Such high-contrast AO-corrected observations have
led to fundamental results in our current understanding of planetary formation
and evolution as well as stellar evolution. AO systems equipped three
generations of instruments, from the first pioneering experiments in the
nineties, to the first wave of instruments on 8m-class telescopes in the years
2000, and finally to the extreme AO systems that have recently started
operations. Along with high-contrast techniques, AO enables to reveal the
circumstellar environment: massive protoplanetary disks featuring spiral arms,
gaps or other asymmetries hinting at on-going planet formation, young giant
planets shining in thermal emission, or tenuous debris disks and micron-sized
dust leftover from collisions in massive asteroid-belt analogs. After
introducing the science case and technical requirements, we will review the
architecture of standard and extreme AO systems, before presenting a few
selected science highlights obtained with recent AO instruments.Comment: 24 pages, 14 figure
Modelling LAI at a regional scale with ISBA-A-gs: comparison with satellite-derived LAI over southwestern France
International audienceA CO2-responsive land surface model (the ISBAA- gs model of M´et´eo-France) is used to simulate photosynthesis and Leaf Area Index (LAI) in southwestern France for a 3-year period (2001–2003). A domain of about 170 000 km2 is covered at a spatial resolution of 8 km. The capability of ISBA-A-gs to reproduce the seasonal and the interannual variability of LAI at a regional scale, is assessed with satellite-derived LAI products. One originates from the CYCLOPES programme using SPOT/VEGETATION data, and two products are based on MODIS data. The comparison reveals discrepancies between the satellite LAI estimates and between satellite and simulated LAI values, both in their intensity and in the timing of the leaf onset. The model simulates higher LAI values for the C3 crops than the satellite observations, which may be due to a saturation effect within the satellite signal or to uncertainties in model parameters. The simulated leaf onset presents a significant delay for C3 crops and mountainous grasslands. In-situ observations at a mid-altitude grassland site show that the generic temperature response of photosynthesis used in the model is not appropriate for plants adapted to the cold climatic conditions of the mountainous areas. This study demonstrates the potential of LAI remote sensing products for identifying and locating models' shortcomings at a regional scale
Epidémie d'infections du site opératoire à Serratia marcescens associée à l'utilisation d'une sonde d'échographie
International audienc
Host galaxy morphologies of X-ray selected AGN: assessing the significance of different black hole fueling mechanisms to the accretion density of the Universe at z~1
We use morphological information of X-ray selected AGN hosts to set limits on
the fraction of the accretion density of the Universe at z~1 that is not likely
to be associated with major mergers. Deep X-ray observations are combined with
high resolution optical data from the Hubble Space Telescope in the AEGIS,
GOODS North and GOODS South fields to explore the morphological breakdown of
X-ray sources in the redshift interval 0.5<z<1.3. The sample is split into
disks, early-type bulge dominated galaxies, peculiar systems and point-sources
in which the nuclear source outshines the host galaxy. The X-ray luminosity
function and luminosity density of AGN at z~1 are then calculated as a function
of morphological type. We find that disk-dominated hosts contribute 30\pm9 per
cent to the total AGN space density and 23\pm6 per cent to the luminosity
density at z~1. We argue that AGN in disk galaxies are most likely fueled not
by major merger events but by minor interactions or internal instabilities. We
find evidence that these mechanisms may be more efficient in producing luminous
AGN (L_X>1e44 erg/s) compared to predictions for the stochastic fueling of
massive black holes in disk galaxies.Comment: Accepted for publication in MNRA
Mid-infrared spectroscopy of infrared-luminous galaxies at z~0.5-3
We present results on low-resolution mid-infrared (MIR) spectra of 70
infrared-luminous galaxies obtained with the Infrared Spectrograph (IRS)
onboard Spitzer. We selected sources from the European Large Area Infrared
Survey (ELAIS) with S15 > 0.8 mJy and photometric or spectroscopic z > 1. About
half of the sample are QSOs in the optical, while the remaining sources are
galaxies, comprising both obscured AGN and starbursts. We classify the spectra
using well-known infrared diagnostics, as well as a new one that we propose,
into three types of source: those dominated by an unobscured AGN (QSOs),
obscured AGN, and starburst-dominated sources. Starbursts concentrate at z ~
0.6-1.0 favored by the shift of the 7.7-micron PAH band into the selection 15
micron band, while AGN spread over the 0.5 < z < 3.1 range. Star formation
rates (SFR) are estimated for individual sources from the luminosity of the PAH
features. An estimate of the average PAH luminosity in QSOs and obscured AGN is
obtained from the composite spectrum of all sources with reliable redshifts.
The estimated mean SFR in the QSOs is 50-100 Mo yr^-1, but the implied FIR
luminosity is 3-10 times lower than that obtained from stacking analysis of the
FIR photometry, suggesting destruction of the PAH carriers by energetic photons
from the AGN. The SFR estimated in obscured AGN is 2-3 times higher than in
QSOs of similar MIR luminosity. This discrepancy might not be due to luminosity
effects or selection bias alone, but could instead indicate a connection
between obscuration and star formation. However, the observed correlation
between silicate absorption and the slope of the near- to mid-infrared spectrum
is compatible with the obscuration of the AGN emission in these sources being
produced in a dust torus.Comment: 32 pages, 24 figures, 15 tables, accepted for publication in MNRA
Survey of childhood empyema in Asia: Implications for detecting the unmeasured burden of culture-negative bacterial disease
<p>Abstract</p> <p>Background</p> <p>Parapneumonic empyema continues to be a disease of significant morbidity and mortality among children despite recent advances in medical management. To date, only a limited number of studies have assessed the burden of empyema in Asia.</p> <p>Methods</p> <p>We surveyed medical records of four representative large pediatric hospitals in China, Korea, Taiwan and Vietnam using <it>ICD</it>-10 diagnostic codes to identify children <16 years of age hospitalized with empyema or pleural effusion from 1995 to 2005. We also accessed microbiology records of cultured empyema and pleural effusion specimens to describe the trends in the epidemiology and microbiology of empyema.</p> <p>Results</p> <p>During the study period, we identified 1,379 children diagnosed with empyema or pleural effusion (China, n = 461; Korea, n = 134; Taiwan, n = 119; Vietnam, n = 665). Diagnoses of pleural effusion (n = 1,074) were 3.5 times more common than of empyema (n = 305), although the relative proportions of empyema and pleural effusion noted in hospital records varied widely between the four sites, most likely because of marked differences in coding practices. Although pleural effusions were reported more often than empyema, children with empyema were more likely to have a cultured pathogen. In addition, we found that median age and gender distribution of children with these conditions were similar across the four countries. Among 1,379 empyema and pleural effusion specimens, 401 (29%) were culture positive. <it>Staphylococcus aureus </it>(n = 126) was the most common organism isolated, followed by <it>Streptococcus pneumoniae </it>(n = 83), <it>Pseudomonas aeruginosa </it>(n = 37) and <it>Klebsiella </it>(n = 35) and <it>Acinetobacter </it>species (n = 34).</p> <p>Conclusion</p> <p>The age and gender distribution of empyema and pleural effusion in children in these countries are similar to the US and Western Europe. <it>S. pneumoniae </it>was the second leading bacterial cause of empyema and pleural effusion among Asian children. The high proportion of culture-negative specimens among patients with pleural effusion or empyema suggests that culture may not be a sufficiently sensitive diagnostic method to determine etiology in the majority of cases. Future prospective studies in different countries would benefit from standardized case definitions and coding practices for empyema. In addition, more sensitive diagnostic methods would improve detection of pathogens and could result in better prevention, treatment and outcomes of this severe disease.</p
Uniform Selection as a Primary Force Reducing Population Genetic Differentiation of Cavitation Resistance across a Species Range
Background: Cavitation resistance to water stress-induced embolism determines plant survival during drought. This adaptive trait has been described as highly variable in a wide range of tree species, but little is known about the extent of genetic and phenotypic variability within species. This information is essential to our understanding of the evolutionary forces that have shaped this trait, and for evaluation of its inclusion in breeding programs. Methodology: We assessed cavitation resistance (P 50), growth and carbon isotope composition in six Pinus pinaster populations in a provenance and progeny trial. We estimated the heritability of cavitation resistance and compared the distribution of neutral markers (FST) and quantitative genetic differentiation (QST), for retrospective identification of the evolutionary forces acting on these traits. Results/Discussion: In contrast to growth and carbon isotope composition, no population differentiation was found for cavitation resistance. Heritability was higher than for the other traits, with a low additive genetic variance (h 2 ns = 0.4360.18, CVA = 4.4%). QST was significantly lower than FST, indicating uniform selection for P50, rather than genetic drift. Putativ
Complex c-di-GMP Signaling Networks Mediate Transition between Virulence Properties and Biofilm Formation in Salmonella enterica Serovar Typhimurium
Upon Salmonella enterica serovar Typhimurium infection of the gut, an early line of defense is the gastrointestinal epithelium which senses the pathogen and intrusion along the epithelial barrier is one of the first events towards disease. Recently, we showed that high intracellular amounts of the secondary messenger c-di-GMP in S. typhimurium inhibited invasion and abolished induction of a pro-inflammatory immune response in the colonic epithelial cell line HT-29 suggesting regulation of transition between biofilm formation and virulence by c-di-GMP in the intestine. Here we show that highly complex c-di-GMP signaling networks consisting of distinct groups of c-di-GMP synthesizing and degrading proteins modulate the virulence phenotypes invasion, IL-8 production and in vivo colonization in the streptomycin-treated mouse model implying a spatial and timely modulation of virulence properties in S. typhimurium by c-di-GMP signaling. Inhibition of the invasion and IL-8 induction phenotype by c-di-GMP (partially) requires the major biofilm activator CsgD and/or BcsA, the synthase for the extracellular matrix component cellulose. Inhibition of the invasion phenotype is associated with inhibition of secretion of the type three secretion system effector protein SipA, which requires c-di-GMP metabolizing proteins, but not their catalytic activity. Our findings show that c-di-GMP signaling is at least equally important in the regulation of Salmonella-host interaction as in the regulation of biofilm formation at ambient temperature
The VLT/NaCo large program to probe the occurrence of exoplanets and brown dwarfs at wide orbits: IV. Gravitational instability rarely forms wide, giant planets<sup>⋆</sup>
Understanding the formation and evolution of giant planets (1 )
at wide orbital separation (5 AU) is one of the goals of direct imaging.
Over the past 15 years, many surveys have placed strong constraints on the
occurrence rate of wide-orbit giants, mostly based on non-detections, but very
few have tried to make a direct link with planet formation theories. In the
present work, we combine the results of our previously published VLT/NaCo large
program with the results of 12 past imaging surveys to constitute a statistical
sample of 199 FGK stars within 100 pc, including 3 stars with sub-stellar
companions. Using Monte Carlo simulations and assuming linear flat
distributions for the mass and semi-major axis of planets, we estimate the
sub-stellar companion frequency to be within 0.75-5.7% at the 68% confidence
level (CL) within 20-300 AU and 0.5-75 , which is compatible with
previously published results. We also compare our results with the predictions
of state-of-the-art population synthesis models based on the gravitational
instability (GI) formation scenario by Forgan & Rice (2013), with and without
scattering. We estimate that in both the scattered and non-scattered
populations, we would be able to detect more than 30% of companions in the 1-75
range (95% CL). With the 3 sub-stellar detections in our sample, we
estimate the fraction of stars that host a planetary system formed by GI to be
within 1.0-8.6% (95% CL). We also conclude that even though GI is not common,
it predicts a mass distribution of wide-orbit massive companions that is much
closer to what is observed than what the core accretion scenario predicts.
Finally, we associate the present paper with the release of the Direct Imaging
Virtual Archive (DIVA, http://cesam.lam.fr/diva/), a public database that aims
at gathering the results of past, present, and future direct imaging surveys.Comment: 20 pages, 11 figures. Accepted for publication in A&
The instrument suite of the European Spallation Source
An overview is provided of the 15 neutron beam instruments making up the initial instrument suite of the
European Spallation Source (ESS), and being made available to the neutron user community. The ESS neutron
source consists of a high-power accelerator and target station, providing a unique long-pulse time structure
of slow neutrons. The design considerations behind the time structure, moderator geometry and instrument
layout are presented.
The 15-instrument suite consists of two small-angle instruments, two reflectometers, an imaging beamline,
two single-crystal diffractometers; one for macromolecular crystallography and one for magnetism, two powder
diffractometers, and an engineering diffractometer, as well as an array of five inelastic instruments comprising
two chopper spectrometers, an inverse-geometry single-crystal excitations spectrometer, an instrument for vibrational
spectroscopy and a high-resolution backscattering spectrometer. The conceptual design, performance
and scientific drivers of each of these instruments are described.
All of the instruments are designed to provide breakthrough new scientific capability, not currently
available at existing facilities, building on the inherent strengths of the ESS long-pulse neutron source of high
flux, flexible resolution and large bandwidth. Each of them is predicted to provide world-leading performance
at an accelerator power of 2 MW. This technical capability translates into a very broad range of scientific
capabilities. The composition of the instrument suite has been chosen to maximise the breadth and depth
of the scientific impact o
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