Neighborhood Environment Perceptions and the Likelihood of Smoking and Alcohol Use

Citation: Jitnarin, N., Heinrich, K. M., Haddock, C. K., Hughey, J., Berkel, L., & Poston, W. S. C. (2015). Neighborhood Environment Perceptions and the Likelihood of Smoking and Alcohol Use. International Journal of Environmental Research and Public Health, 12(1), 784-799. doi:10.3390/ijerph120100784Neighborhood characteristics are important correlates for a variety of health outcomes. Among several health risk behaviors, smoking and alcohol use have significant consequences. Perceptions of neighborhood problems are associated with depressive symptoms, lower physical activity, and lower quality of life. However, it is unclear which perceived aspects of neighborhoods might be related to smoking and drinking. We examined whether perceived neighborhood characteristics were associated with smoking and drinking patterns using data from US metropolitan Midwestern area adults. Participants completed surveys including sociodemographic characteristics, neighborhood perceptions, behavioral and psychological health. For men, negative perceptions of neighborhood infrastructures were significant predictors for smoking and binge drinking. Among women, no perceived environmental factors were associated with smoking or drinking. However, education was a significant negative predictor for smoking. As age increased, the likelihood of using cigarettes, heavy and binge drinking in women decreased significantly. Depression was a positive predictor for smoking and heavy drinking in men and women, respectively. These findings indicate that the perceived neighborhood infrastructure was predictive of health behaviors among men, even after adjusting for key confounders. Closer attention may need to be paid to the role of neighborhood environmental characteristics along with individual-level characteristics in influencing unhealthy behaviors

Native fish in Northland: application of the River Values Assessment System (RiVAS and RiVAS+)

The fourth application of the River Values Assessment System (RiVAS and RiVAS+) for native fisheries value was made in the Northland region. Data for nine out of ten indicators were provided from modelling undertaken by Cawthron Institute using a variety of databases including the NZFFD and FENZ. The expert panel then checked the modelling results and adjusted where appropriate based on local knowledge, and it populated the Population Stronghold indicator. Of 27 river catchment/clusters evaluated, nine were considered of national significance, namely the Bay of Islands North, Bay of Islands South, East Coast, Herekino, Hokianga, Mangamuka, Waihou, Waipoua and Wairoa. The Wairoa scored very poorly for all attributes other than presence of many at risk species. The remaining 18 are of regional significance. No river catchment/clusters were identified as being of local significance. The RIVAS+ identified work that can be done to reduce the inference on migratory fish movements caused by a barrier on the Waipoua River.This work was funded by Northland Regional Council and we gratefully acknowledge their support

Transfer/Breakup Modes in the 6He+209Bi Reaction Near and Below the Coulomb Barrier

Reaction products from the interaction of 6He with 209Bi have been measured at energies near the Coulomb barrier. A 4He group of remarkable intensity, which dominates the total reaction cross section, has been observed. The angular distribution of the group suggests that it results primarily from a direct nuclear process. It is likely that this transfer/breakup channel is the doorway state that accounts for the previously observed large sub-barrier fusion enhancement in this system.Comment: 4 pages; 3 figure

Transfer Functions for Protein Signal Transduction: Application to a Model of Striatal Neural Plasticity

We present a novel formulation for biochemical reaction networks in the context of signal transduction. The model consists of input-output transfer functions, which are derived from differential equations, using stable equilibria. We select a set of 'source' species, which receive input signals. Signals are transmitted to all other species in the system (the 'target' species) with a specific delay and transmission strength. The delay is computed as the maximal reaction time until a stable equilibrium for the target species is reached, in the context of all other reactions in the system. The transmission strength is the concentration change of the target species. The computed input-output transfer functions can be stored in a matrix, fitted with parameters, and recalled to build discrete dynamical models. By separating reaction time and concentration we can greatly simplify the model, circumventing typical problems of complex dynamical systems. The transfer function transformation can be applied to mass-action kinetic models of signal transduction. The paper shows that this approach yields significant insight, while remaining an executable dynamical model for signal transduction. In particular we can deconstruct the complex system into local transfer functions between individual species. As an example, we examine modularity and signal integration using a published model of striatal neural plasticity. The modules that emerge correspond to a known biological distinction between calcium-dependent and cAMP-dependent pathways. We also found that overall interconnectedness depends on the magnitude of input, with high connectivity at low input and less connectivity at moderate to high input. This general result, which directly follows from the properties of individual transfer functions, contradicts notions of ubiquitous complexity by showing input-dependent signal transmission inactivation.Comment: 13 pages, 5 tables, 15 figure

More than skin deep: Functional genomic basis for resistance to Amphibian Chytridiomycosis

The amphibian-killing chytrid fungus Batrachochytriumdendrobatidis (Bd) is one of themost generalist pathogens known, capable of infecting hundreds of species globally and causing widespread population declines and extinctions. However, some host species are seemingly unaffected by Bd, tolerating or clearing infections without clinical signs of disease. Variation in host immune responses is commonly evoked for these resistant or tolerant species, yet to date,we have nodirect comparisonof amphibian species responses to infection at the level of gene expression. In this study,we challenged four CentralAmerican frog species that vary in Bd susceptibility, with a sympatric virulent strain of the pathogen. We compared skin and spleen orthologous gene expression using differential expression tests and coexpression gene network analyses.Wefound that resistant species have reduced skin inflammatory responses andincreased expressionofgenes involved inskin integrity. Incontrast, onlyhighly susceptible species exhibited suppressionof splenic T-cell genes. We conclude that resistance to chytridiomycosis may be related to a species’ ability to escape the immunosuppressive activity of the fungus. Moreover, our results indicate that within-species differences in splenic proteolytic enzyme gene expression may contribute to intraspecific variation in survival. This first comparison of amphibian functional immunogenomic architecture in response to Bd provides insights into key genetic mechanisms underlying variation in disease outcomes among amphibian species

Obesity and Physical Activity Variance by Income and Ethnicity in Kansas City

Purpose: Although obesity and physical activity prevalence systematically vary by income and ethnicity, it is unclear how well census data represent actual conditions. Using data from the Kansas City Built Environment and Health Study, we examined whether differences in measured obesity prevalence and self-reported physical activity would systematically vary by both census block group median income and percent ethnic minority and self-reported income and ethnicity. Methods: Participants included 586 adults; average age 45±14.7. Most participants were female (69.8%), married (51.5%), had some college or more (72.7%) and had incomes ≤$60,000 (54.6%). Households were solicited from 21 census block groups, stratified by household income and percent ethnic minority across the Kansas City Metropolitan area. After obtaining informed consent, trained data collectors conducted 60-minute interviews. Physical activity was measured with the International Physical Activity Questionnaire. Height was measured with a portable stadiometer and weight and percent body fat (%BF) percentages were measured using a Tanita scale. Results: Using calculated BMI data, 33.3% were obese; 55.8% were obese when using %BF. Comparison by census block group showed significantly lower obesity rates (BMI) for the highest income tertile (p=.01) and the lower ethnic minority tertile (p=.009 BMI; p\u3c.001 %BF). Self-reported ethnicity data showed significantly higher obesity rates for both African Americans and American Indians (p=.001 BMI; p\u3c.001 %BF). Overall, physical activity levels were low, with only 19.1% (n=112) meeting walking, 9.4% (n=55) meeting moderate (both 150+minutes/week), and 24.7% (n=145) meeting vigorous recommendations (75+minutes/week). Both census and self-reported income were positively correlated with meeting walking recommendations (p\u3c.01) and meeting vigorous activity recommendations (p\u3c.05 and p\u3c.05, respectively). Meeting vigorous activity recommendations was significantly more likely for those in the lower ethnic minority tertile (p=.04). Conclusions: We found systematic variation across income and ethnicity for both obesity and physical activity, with worse rates for lower income individuals, Blacks and American Indians. BMI may have underestimated obesity prevalence. Future research should determine related environmental correlates

Limits on diffuse fluxes of high energy extraterrestrial neutrinos with the AMANDA-B10 detector

Data from the AMANDA-B10 detector taken during the austral winter of 1997 have been searched for a diffuse flux of high energy extraterrestrial muon-neutrinos, as predicted from, e.g., the sum of all active galaxies in the universe. This search yielded no excess events above those expected from the background atmospheric neutrinos, leading to upper limits on the extraterrestrial neutrino flux. For an assumed E^-2 spectrum, a 90% classical confidence level upper limit has been placed at a level E^2 Phi(E) = 8.4 x 10^-7 GeV cm^-2 s^-1 sr^-1 (for a predominant neutrino energy range 6-1000 TeV) which is the most restrictive bound placed by any neutrino detector. When specific predicted spectral forms are considered, it is found that some are excluded.Comment: Submitted to Physical Review Letter

A First Search for coincident Gravitational Waves and High Energy Neutrinos using LIGO, Virgo and ANTARES data from 2007

We present the results of the first search for gravitational wave bursts associated with high energy neutrinos. Together, these messengers could reveal new, hidden sources that are not observed by conventional photon astronomy, particularly at high energy. Our search uses neutrinos detected by the underwater neutrino telescope ANTARES in its 5 line configuration during the period January - September 2007, which coincided with the fifth and first science runs of LIGO and Virgo, respectively. The LIGO-Virgo data were analysed for candidate gravitational-wave signals coincident in time and direction with the neutrino events. No significant coincident events were observed. We place limits on the density of joint high energy neutrino - gravitational wave emission events in the local universe, and compare them with densities of merger and core-collapse events.Comment: 19 pages, 8 figures, science summary page at http://www.ligo.org/science/Publication-S5LV_ANTARES/index.php. Public access area to figures, tables at https://dcc.ligo.org/cgi-bin/DocDB/ShowDocument?docid=p120000

Test of two prototype high-temperature superconducting transmission cables

Two 500-A class prototype high-temperature superconducting cables have been constructed by Southwire Company and tested at Oak Ridge National Laboratory (ORNL). In the first cable, no insulation was used to separate the individual HTS tapes. In the second cable, Kapton tape was used to insulate the HTS tapes between successive layers for the study of AC loss and current distribution. The cables were tested with both DC and AC currents in liquid nitrogen from 77 to 69 K. Both cables achieved DC critical current, I{sub c} greater than 500 A. A calorimetric technique that measures the cable temperature rise under ac currents was used to measure the ac loss of the cables. The un-insulated cable showed a cryoresistive behavior under the 60 Hz AC currents. The insulated cable started to show measurable loss at current where there was corresponding resistive loss

Swift follow-up observations of candidate gravitational-wave transient events

We present the first multi-wavelength follow-up observations of two candidate gravitational-wave (GW) transient events recorded by LIGO and Virgo in their 2009-2010 science run. The events were selected with low latency by the network of GW detectors and their candidate sky locations were observed by the Swift observatory. Image transient detection was used to analyze the collected electromagnetic data, which were found to be consistent with background. Off-line analysis of the GW data alone has also established that the selected GW events show no evidence of an astrophysical origin; one of them is consistent with background and the other one was a test, part of a "blind injection challenge". With this work we demonstrate the feasibility of rapid follow-ups of GW transients and establish the sensitivity improvement joint electromagnetic and GW observations could bring. This is a first step toward an electromagnetic follow-up program in the regime of routine detections with the advanced GW instruments expected within this decade. In that regime multi-wavelength observations will play a significant role in completing the astrophysical identification of GW sources. We present the methods and results from this first combined analysis and discuss its implications in terms of sensitivity for the present and future instruments.Comment: Submitted for publication 2012 May 25, accepted 2012 October 25, published 2012 November 21, in ApJS, 203, 28 ( http://stacks.iop.org/0067-0049/203/28 ); 14 pages, 3 figures, 6 tables; LIGO-P1100038; Science summary at http://www.ligo.org/science/Publication-S6LVSwift/index.php ; Public access area to figures, tables at https://dcc.ligo.org/cgi-bin/DocDB/ShowDocument?docid=p110003