221 research outputs found

    Do Race and Ethnicity Influence Turnover Intention in Newly Licensed Registered Nurses?

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    Background: Demand for health care services is rising while newly licensed nurses vacate employment positions at alarming rates. Healthcare leadership has called for an increased diversification of the healthcare workforce, but the workplace experience of nonwhite nurses in the first years has not been assessed. Methods: This study utilized a quantitative cross-sectional survey design. The sample was limited to newly licensed nurses with no prior experience as a nurse. Linear regression models were constructed to determine which personal and structural attributes are associated with turnover intention, stratified by race and ethnicity. Hierarchical, backwards stepwise selection was used to build the final model. Results: The majority of respondents were white English-speaking females, never married, holding a BSN and working in an acute care hospital. Nurses who speak a language other than English at home are treated more poorly than primary English speakers. Hispanics are most likely to report a negative work environment, a hostile climate, general incivility and inappropriate jokes. Turnover intention was associated with months at the current job, a negative work environment including experiencing incivility, not having enough time to do the things that must be done, and confidence in the ability to do one’s job list. Blacks are likely to report a high turnover intention but remain in the current job while acknowledging a hostile environment and general incivility. Many nurses employed in non-acute care settings are nonwhite, report higher workload scores and high patient assignments. Conclusions: Nonwhite nurses report negative work environments and high intention to leave but remain in their jobs. Among the full sample of newly licensed nurses, months at the current job, a negative work environment, including experiencing incivility, not having enough time to do the things that must be done, and confidence in the ability to do one’s job were associated with turnover intention. Efforts to diversify the workforce must include education to prepare minority nurses for the environment they may encounter, including uncivil behavior and high workloads. Policy initiatives must address the treatment of new nurses and support new nurses as they transition to the professional role

    Age and Ovariectomy Abolish Beneficial Effects of Female Sex on Rat Ventricular Myocytes Exposed to Simulated Ischemia and Reperfusion

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    Sex differences in responses to myocardial ischemia have been described, but whether cardiomyocyte function is influenced by sex in the setting of ischemia and reperfusion has not been elucidated. This study compared contractions and intracellular Ca2+ in isolated ventricular myocytes exposed to ischemia and reperfusion. Cells were isolated from anesthetized 3-month-old male and female Fischer 344 rats, paced at 4 Hz (37°C), exposed to simulated ischemia (20 mins) and reperfused. Cell shortening (edge detector) and intracellular Ca2+ (fura-2) were measured simultaneously. Cell viability was assessed with Trypan blue. Ischemia reduced peak contractions and increased Ca2+ levels equally in myocytes from both sexes. However, contraction amplitudes were reduced in reperfusion in male myocytes, while contractions recovered to exceed control levels in females (62.6±5.1 vs. 140.1±15.8%; p<0.05). Only 60% of male myocytes excluded trypan blue dye after ischemia and reperfusion, while all female cardiomyocytes excluded the dye (p<0.05). Parallel experiments were conducted in myocytes from ∼24-month-old female rats or 5–6-month-old rats that had an ovariectomy at 3–4 weeks of age. Beneficial effects of female sex on myocyte viability and contractile dysfunction in reperfusion were abolished in cells from 24-month-old females. Aged female myocytes also exhibited elevated intracellular Ca2+ and alternans in ischemia. Cells from ovariectomized rats displayed increased Ca2+ transients and spontaneous activity in ischemia compared to sham-operated controls. None of the myocytes from ovariectomized rats were viable after 15 minutes of ischemia, while 75% of sham cells remained viable at end of reperfusion (p<0.05). These findings demonstrate that cardiomyocytes from young adult females are more resistant to ischemia and reperfusion injury than cells from males. Age and OVX abolish these beneficial effects and induce Ca2+ dysregulation at the level of the cardiomyocyte. Thus, beneficial effects of estrogen in ischemia and reperfusion are mediated, in part, by effects on cardiomyocytes

    Towards nationally curated data archives for clinical radiology image analysis at scale: Learnings from national data collection in response to a pandemic

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    The prevalence of the coronavirus SARS-CoV-2 disease has resulted in the unprecedented collection of health data to support research. Historically, coordinating the collation of such datasets on a national scale has been challenging to execute for several reasons, including issues with data privacy, the lack of data reporting standards, interoperable technologies, and distribution methods. The coronavirus SARS-CoV-2 disease pandemic has highlighted the importance of collaboration between government bodies, healthcare institutions, academic researchers and commercial companies in overcoming these issues during times of urgency. The National COVID-19 Chest Imaging Database, led by NHSX, British Society of Thoracic Imaging, Royal Surrey NHS Foundation Trust and Faculty, is an example of such a national initiative. Here, we summarise the experiences and challenges of setting up the National COVID-19 Chest Imaging Database, and the implications for future ambitions of national data curation in medical imaging to advance the safe adoption of artificial intelligence in healthcare

    Re-visiting Meltsner: Policy Advice Systems and the Multi-Dimensional Nature of Professional Policy Analysis

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    10.2139/ssrn.15462511-2

    Energy applications of ionic liquids

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    Ionic liquids offer a unique suite of properties that make them important candidates for a number of energy related applications. Cation–anion combinations that exhibit low volatility coupled with high electrochemical and thermal stability, as well as ionic conductivity, create the possibility of designing ideal electrolytes for batteries, super-capacitors, actuators, dye sensitised solar cells and thermoelectrochemical cells. In the field of water splitting to produce hydrogen they have been used to synthesize some of the best performing water oxidation catalysts and some members of the protic ionic liquid family co-catalyse an unusual, very high energy efficiency water oxidation process. As fuel cell electrolytes, the high proton conductivity of some of the protic ionic liquid family offers the potential of fuel cells operating in the optimum temperature region above 100 °C. Beyond electrochemical applications, the low vapour pressure of these liquids, along with their ability to offer tuneable functionality, also makes them ideal as CO2 absorbents for post-combustion CO2 capture. Similarly, the tuneable phase properties of the many members of this large family of salts are also allowing the creation of phase-change thermal energy storage materials having melting points tuned to the application. This perspective article provides an overview of these developing energy related applications of ionic liquids and offers some thoughts on the emerging challenges and opportunities

    Progress in the use of ionic liquids as electrolyte membranes in fuel cells

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    This work provides a critical review of the progress in the use of Room Temperature Ionic Liquids (RTILs) as Proton Exchange Membrane (PEM) electrolytes in Fuel Cells (FCs). It is well-known that for an efficient early commercialisation of this technology it is necessary to develop a proton exchange membrane with high proton conductivity without water dependency capable of working at temperatures above 100 °C. The use of ionic liquids as electrolytes in electrochemical devices is an emerging field due to their high conductivity, as well as their thermal, chemical and electrochemical stability under anhydrous conditions. This paper attempts to give a general overview of the state-of-the-art, identifies the key factors for future research and summarises the recent progress in the use of ionic liquids as an innovative type of PEMs.This research was supported by the Ministry of Education, Culture and Sport under the Project CTQ2012-31639 (MINECO, SPAIN-FEDER2001–2013)
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