66 research outputs found
Relativistic heavy ion collisions with realistic non-equilibrium mean fields
We study the influence of non-equilibrium phase space effects on the dynamics
of heavy ion reactions within the relativistic BUU approach. We use realistic
Dirac-Brueckner-Hartree-Fock (DBHF) mean fields determined for
two-Fermi-ellipsoid configurations, i.e. for colliding nuclear matter, in a
local phase space configuration approximation (LCA). We compare to DBHF mean
fields in the local density approximation (LDA) and to the non-linear Walecka
model. The results are further compared to flow data of the reaction on
at 400 MeV per nucleon measured by the FOPI collaboration. We find that
the DBHF fields reproduce the experiment if the configuration dependence is
taken into account. This has also implications on the determination of the
equation of state from heavy ion collisions.Comment: Physics Letters B in press; 10 pages, Postscript file replaced by
Latex file and 3 Postscript figure
Heavy ion collisions with non-equilibrium Dirac-Brueckner mean fields
The influence of realistic interactions on the reaction dynamics in
intermediate energy heavy ion collisions is investigated. The mean field in
relativistic transport calculations is derived from microscopic Dirac-Brueckner
(DB) self-energies, taking non-equilibrium effects, in particular the
anisotropy of the local phase space configurations, into account. Thus this
approach goes beyond the local density approximation. A detailed analysis of
various in-plane and out-of-plane flow observables is presented for Au on Au
reactions at incident energies ranging from 250 to 800 A.MeV and the results
are compared to recent measurements of the FOPI collaboration. An overall good
agreement with in-plane flow data and a reasonable description of the
out-of-plane emission is achieved. For these results the intrinsic momentum
dependence of the non-equilibrium mean fields is important. On the other hand,
the local density approximation with the same underlying DB forces as well as a
standard non-linear version of the model are less successful in
describing the present data. This gives evidence of the applicability of self
energies derived from the DB approach to nuclear matter also far from
saturation and equilibrium.Comment: 63 pages Latex, using Elsevier style, 20 ps-figures, to appear in
Nucl. Phys.
"Tomography" of the cluster structure of light nuclei via relativistic dissociation
These lecture notes present the capabilities of relativistic nuclear physics
for the development of the physics of nuclear clusters. Nuclear track emulsion
continues to be an effective technique for pilot studies that allows one, in
particular, to study the cluster dissociation of a wide variety of light
relativistic nuclei within a common approach. Despite the fact that the
capabilities of the relativistic fragmentation for the study of nuclear
clustering were recognized quite a long time ago, electronic experiments have
not been able to come closer to an integrated analysis of ensembles of
relativistic fragments. The continued pause in the investigation of the "fine"
structure of relativistic fragmentation has led to resumption of regular
exposures of nuclear emulsions in beams of light nuclei produced for the first
time at the Nuclotron of the Joint Institute for Nuclear Research (JINR,
Dubna). To date, an analysis of the peripheral interactions of relativistic
isotopes of beryllium, boron, carbon and nitrogen, including radioactive ones,
with nuclei of the emulsion composition, has been performed, which allows the
clustering pattern to be presented for a whole family of light nuclei.Comment: ISBN 978-3-319-01076-2. 55 pages, 28 figure
Anisotropic flow of charged hadrons, pions and (anti-)protons measured at high transverse momentum in Pb-Pb collisions at TeV
The elliptic, , triangular, , and quadrangular, , azimuthal
anisotropic flow coefficients are measured for unidentified charged particles,
pions and (anti-)protons in Pb-Pb collisions at TeV
with the ALICE detector at the Large Hadron Collider. Results obtained with the
event plane and four-particle cumulant methods are reported for the
pseudo-rapidity range at different collision centralities and as a
function of transverse momentum, , out to GeV/.
The observed non-zero elliptic and triangular flow depends only weakly on
transverse momentum for GeV/. The small dependence
of the difference between elliptic flow results obtained from the event plane
and four-particle cumulant methods suggests a common origin of flow
fluctuations up to GeV/. The magnitude of the (anti-)proton
elliptic and triangular flow is larger than that of pions out to at least
GeV/ indicating that the particle type dependence persists out
to high .Comment: 16 pages, 5 captioned figures, authors from page 11, published
version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/186
Centrality dependence of charged particle production at large transverse momentum in Pb-Pb collisions at TeV
The inclusive transverse momentum () distributions of primary
charged particles are measured in the pseudo-rapidity range as a
function of event centrality in Pb-Pb collisions at
TeV with ALICE at the LHC. The data are presented in the range
GeV/ for nine centrality intervals from 70-80% to 0-5%.
The Pb-Pb spectra are presented in terms of the nuclear modification factor
using a pp reference spectrum measured at the same collision
energy. We observe that the suppression of high- particles strongly
depends on event centrality. In central collisions (0-5%) the yield is most
suppressed with at -7 GeV/. Above
GeV/, there is a significant rise in the nuclear modification
factor, which reaches for GeV/. In
peripheral collisions (70-80%), the suppression is weaker with almost independently of . The measured nuclear
modification factors are compared to other measurements and model calculations.Comment: 17 pages, 4 captioned figures, 2 tables, authors from page 12,
published version, figures at
http://aliceinfo.cern.ch/ArtSubmission/node/284
Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility
Genome-wide association studies (GWASs) have identified hundreds of loci associated with Crohn's disease (CD). However, as with all complex diseases, robust identification of the genes dysregulated by noncoding variants typically driving GWAS discoveries has been challenging. Here, to complement GWASs and better define actionable biological targets, we analyzed sequence data from more than 30,000 patients with CD and 80,000 population controls. We directly implicate ten genes in general onset CD for the first time to our knowledge via association to coding variation, four of which lie within established CD GWAS loci. In nine instances, a single coding variant is significantly associated, and in the tenth, ATG4C, we see additionally a significantly increased burden of very rare coding variants in CD cases. In addition to reiterating the central role of innate and adaptive immune cells as well as autophagy in CD pathogenesis, these newly associated genes highlight the emerging role of mesenchymal cells in the development and maintenance of intestinal inflammation.Large-scale sequence-based analyses identify novel risk variants and susceptibility genes for Crohn's disease, and implicate mesenchymal cell-mediated intestinal homeostasis in disease etiology.Cellular mechanisms in basic and clinical gastroenterology and hepatolog
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