Gambling problems and military- and health-related behaviour in UK Armed Forces veterans

Internationally, problem gambling is elevated in Armed Forces veterans compared to the general population. Here, we re-examined the prevalence of problem gambling in veterans and non-veterans residing in England using an established large dataset and investigated whether gambling was associated with length of service, common mental health disorders, substance abuse, or financial management history. Using the 2007 Adult Psychiatric Morbidity Survey, 257 post-national service veterans and 514 age- and sex-matched controls were compared. Veterans had significantly higher rates of problem gambling than non-veterans. Male veterans were more likely than non-veterans to have experienced a traumatic event. The relationship between veteran status and problem gambling was not explained by differences in mental health conditions, substance abuse, or financial management. No differences were found for length of service. Further research is required with larger samples targeting problem gambling and Armed Forces experience in the United Kingdom population using contemporary diagnostic criteria

Biomarkers of aging associated with past treatments in breast cancer survivors.

Radiation and chemotherapy are effective treatments for cancer, but are also toxic to healthy cells. Little is known about whether prior exposure to these treatments is related to markers of cellular aging years later in breast cancer survivors. We examined whether past exposure to chemotherapy and/or radiation treatment was associated with DNA damage, telomerase activity, and telomere length 3-6 years after completion of primary treatments in breast cancer survivors (stage 0-IIIA breast cancer at diagnosis). We also examined the relationship of these cellular aging markers with plasma levels of Interleukin (IL)-6, soluble TNF-receptor-II (sTNF-RII), and C-reactive protein (CRP). Ninety-four women (36.4-69.5 years; 80% white) were evaluated. Analyses adjusting for age, race, BMI, and years from last treatment found that women who had prior exposure to chemotherapy and/or radiation compared to women who had previously received surgery alone were more likely to have higher levels of DNA damage (P = .02) and lower telomerase activity (P = .02), but did not have differences in telomere length. More DNA damage and lower telomerase were each associated with higher levels of sTNF-RII (P's < .05). We found that exposure to chemotherapy and/or radiation 3-6 years prior was associated with markers of cellular aging, including higher DNA damage and lower telomerase activity, in post-treatment breast cancer survivors. Furthermore, these measures were associated with elevated inflammatory activation, as indexed by sTNF-RII. Given that these differences were observed many years after the treatment, the findings suggest a long lasting effect of chemotherapy and/or radiation exposure

Creating a Discipline-specific Commons for Infectious Disease Epidemiology

Objective: To create a commons for infectious disease (ID) epidemiology in which epidemiologists, public health officers, data producers, and software developers can not only share data and software, but receive assistance in improving their interoperability. Materials and Methods: We represented 586 datasets, 54 software, and 24 data formats in OWL 2 and then used logical queries to infer potentially interoperable combinations of software and datasets, as well as statistics about the FAIRness of the collection. We represented the objects in DATS 2.2 and a software metadata schema of our own design. We used these representations as the basis for the Content, Search, FAIR-o-meter, and Workflow pages that constitute the MIDAS Digital Commons. Results: Interoperability was limited by lack of standardization of input and output formats of software. When formats existed, they were human-readable specifications (22/24; 92%); only 3 formats (13%) had machine-readable specifications. Nevertheless, logical search of a triple store based on named data formats was able to identify scores of potentially interoperable combinations of software and datasets. Discussion: We improved the findability and availability of a sample of software and datasets and developed metrics for assessing interoperability. The barriers to interoperability included poor documentation of software input/output formats and little attention to standardization of most types of data in this field. Conclusion: Centralizing and formalizing the representation of digital objects within a commons promotes FAIRness, enables its measurement over time and the identification of potentially interoperable combinations of data and software.Comment: 12 pages, 6 figure

The High Energy view of the Broad Line Radio Galaxy 3C 111

We present the analysis of Suzaku and XMM-Newton observations of the broad-line radio galaxy (BLRG) 3C 111. Its high energy emission shows variability, a harder continuum with respect to the radio quiet AGN population, and weak reflection features. Suzaku found the source in a minimum flux level; a comparison with the XMM-Newton data implies an increase of a factor of 2.5 in the 0.5-10 keV flux, in the 6 months separating the two observations. The iron K complex is detected in both datasets, with rather low equivalent width(s). The intensity of the iron K complex does not respond to the change in continuum flux. An ultra-fast, high-ionization outflowing gas is clearly detected in the XIS data; the absorber is most likely unstable. Indeed, during the XMM-Newton observation, which was 6 months after, the absorber was not detected. No clear roll-over in the hard X-ray emission is detected, probably due to the emergence of the jet as a dominant component in the hard X-ray band, as suggested by the detection above ~ 100 keV with the GSO on-board Suzaku, although the present data do not allow us to firmly constrain the relative contribution of the different components. The fluxes observed by the gamma-ray satellites CGRO and Fermi would be compatible with the putative jet component if peaking at energies E ~ 100 MeV. In the X-ray band, the jet contribution to the continuum starts to be significant only above 10 keV. If the detection of the jet component in 3C 111 is confirmed, then its relative importance in the X-ray energy band could explain the different observed properties in the high-energy emission of BLRGs, which are otherwise similar in their other multiwavelength properties. Comparison between X-ray and gamma-ray data taken at different epochs suggests that the strong variability observed for 3C 111 is probably driven by a change in the primary continuum.Comment: Accepted for publication in MNRAS; 15 pages, 9 figures, 5 table

The Grizzly, October 30, 2008

Sounds of NYC Poet Tracie Morris • Plan to Vote? UC Students Take Note: Polling Location Change • Business Management Students Assist Charitable Causes • Colin Powell Publicly Endorses Obama • Young and Engaged: Planning for Life Beyond UC Years • Hingston of Philadelphia Speaks at UC • Faculty Spotlight on Philosophy Professor Kelly Sorensen • More from Students Studying Abroad: UC in Germany • Opinions: We Will Overcome: Positive Psychology in America; Logical Reason Behind Refusal to Vote; Controversy for the Republicans • Football Quarterback Nick Dye Great Leader for Young Team • Kelly Hosier: Sole, Shy Senior on UC Women\u27s Volleyball Teamhttps://digitalcommons.ursinus.edu/grizzlynews/1773/thumbnail.jp

Observational evidence for gravitationally trapped massive axion(-like) particles

Unexpected astrophysical observations can be explained by gravitationally captured massive particles, which are produced inside the Sun or other Stars and are accumulated over cosmic times. Their radiative decay in solar outer space would give rise to a `self-irradiation' of the whole star, providing the time-independent component of the corona heating source. In analogy with the Sun-irradiated Earth atmosphere, the temperature and density gradient in the corona - chromosphere transition region is suggestive for an omnipresent irradiation of the Sun. The same scenario fits other astrophysical X-ray observations. The radiative decay of a population of such elusive particles mimics a hot gas. X-ray observatories, with an unrivalled sensitivity below ~10 keV, can search for such particles. The elongation angle relative to the Sun is the relevant new parameter.Comment: 35 pages, LaTeX, 9 figures. Accepted by Astroparticle Physic