138 research outputs found
Epistemic brokerage in the bio-property narrative: Contributions to explaining opposition to transgenic technologies in agriculture
Persistent Poverty and Path Dependency: Agrarian Reform: Lessons from the United States and India
Summaries The historical experience of the United States, where aggregate wealth multiplied in abundance but persistent poverty is glaring, offers concrete illustration that growth is not a sufficient condition for poverty alleviation in the transition from agrarian society. In contrast, the State of Kerala in South India abolished an agrarian system based on agrestic serfdom and slavery in a compressed time period and has been notably successful in reducing the incidence of poverty despite income and growth rates well below the Indian mean. Though sometimes romanticised, the ‘Kerala model’ offers both positive and negative lessons from its thorough agrarian reform. Though less prominent in public discourse after the end of the Cold War, agrarian reform still offers significant poverty reduction advantages in comparison with alternatives
Fungal regulatory evolution: cis and trans in the balance
available in PMC 2010 June 17.Regulatory divergence is likely a major driving force in evolution. Comparative genomics is being increasingly used to infer the evolution of gene regulation. Ascomycota fungi are uniquely suited among eukaryotes for regulatory evolution studies, due to broad phylogenetic scope, many sequenced genomes, and tractability of genomic analysis. Here we review recent advances in the identification of the contribution of cis- and trans-factors to expression divergence. Whereas current strategies have led to the discovery of surprising signatures and mechanisms, we still understand very little about the adaptive role of regulatory evolution. Empirical studies including experimental evolution, comparative functional genomics and hybrid and engineered strains are showing early promise toward deciphering the contribution of regulatory divergence to adaptation.Human Frontier Science Program (Strasbourg, France)Howard Hughes Medical InstituteBurroughs Wellcome Fund (Career Award)Alfred P. Sloan Foundatio
Inter-professional Service Learning to Increase Students\u27 Understanding of Migrant Latino Health
Learning Objectives
At the end of this seminar participants will be able to:
1.Explain the relevance of inter-professional, cultural competent, global health approaches to health assessment and interventions at home and abroad.
2.Identify evidence-based programs to improve target population health, utilizing the CLAS standards to advance health equity, improve quality and help eliminate health disparities.
3.Design a service learning inter-professional health education course with teaching strategies for cultural competency training that utilizes academic and clinical partnerships
iSchools and archival studies
Whispers and rumors about the iSchool movement lead some to fear that this represents yet another shift away from the valued traditions of library schools, threatening something far different than what library science pioneers ever envisioned. Predating the iSchool movement, however, were other programmatic shifts such as those that led to the formalization of graduate archival education. This essay argues that such evolution is essential to our future, as iSchools tackle the increasingly complex issues confronting a digital society. We consider the mission and history of iSchools and of archival studies, the basic elements and concepts of archival studies that are critical to iSchools, and the relationship between iSchools and the changing nature of personal and institutional archives. © 2009 Springer Science+Business Media B.V
CANELC: constructing an e-language corpus
This paper reports on the construction of CANELC: the Cambridge and Nottingham e-language Corpus.3 CANELC is a one million word corpus of digital communication in English, taken from online discussion boards, blogs, tweets, emails and SMS messages. The paper outlines the approaches used when planning the corpus: obtaining consent; collecting the data and compiling the corpus database.
This is followed by a detailed analysis of some of the patterns of language used in the corpus. The analysis includes a discussion of the key words and phrases used as well as the common themes and semantic associations connected with the data. These discussions form the basis of an investigation of how e-language operates in both similar and different ways to spoken and written records of communication (as evidenced by the BNC - British National Corpus).
3 CANELC stands for Cambridge and Nottingham e-language Corpus. This corpus has been built as part of a collaborative project between The University of Nottingham and Cambridge University Press with whom sole copyright of the annotated corpus resides. CANELC comprises one-million words of digital English taken from SMS messages, blogs, tweets, discussion board content and private/business emails. Plans to extend the corpus are under discussion. The legal dimension to corpus ‘ownership’ of some forms of unannotated data is a complex one and is under constant review. At the present time the annotated corpus is only available to authors and researchers working for CUP and is not more generally available
The genetic architecture of the human cerebral cortex
The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, we conducted a genome-wide association meta-analysis of brain magnetic resonance imaging data from 51,665 individuals. We analyzed the surface area and average thickness of the whole cortex and 34 regions with known functional specializations. We identified 199 significant loci and found significant enrichment for loci influencing total surface area within regulatory elements that are active during prenatal cortical development, supporting the radial unit hypothesis. Loci that affect regional surface area cluster near genes in Wnt signaling pathways, which influence progenitor expansion and areal identity. Variation in cortical structure is genetically correlated with cognitive function, Parkinson's disease, insomnia, depression, neuroticism, and attention deficit hyperactivity disorder
- …