Efecto de la edad del rebrote y el clima en la composición química de Cenchrus purpureus en ecosistemas degradados de Cuba

The objective of this work was to determine the effect of age and climate on the chemical composition of Cenchrus purpureus in degraded ecosystems of Cuba. An experiment was carried out in two well-defined periods: slightly rainy (January to April) and rainy (July to October). The treatments (regrowth ages: 30, 45, 60, 75, 90 105 days) were distributed in a randomized block design with four replicas. The structural constituents of the cell wall, minerals (calcium and phosphorus), and digestibility of dry and organic matter were determined. The neutral detergent fiber showed a behavior defined by the climatic season (72.37%) in rains and 69.67% in few rains). The elements of the climate showed a high relationship with the chemical composition and linear regression models were adjusted with high coefficients of determination, greater than 0.71 in the two periods evaluated; the rainfall and maximum temperature variables were the ones that provided the greatest adjustments. With the increase in age, the quality of the plant decreased, and of climatic factors, rainfall and maximum temperature are those that most affect the nutritional quality of the plant.El objetivo del presente trabajo fue determinar el efecto de la edad de rebrote y del clima en la composición química del Cenchrus purpureus en ecosistemas degradados de Cuba. Se realizó un experimento en dos períodos bien definidos: poco lluvioso (enero a abril) y lluvioso (julio a octubre). Los tratamientos (edades de rebrote: 30, 45, 60, 75, 90 105 días) se distribuyeron en un diseño de bloques al azar con cuatro réplicas. Se determinaron los constituyentes estructurales de la pared celular, minerales (calcio y fósforo), y digestibilidad de la materia seca y orgánica. La fibra detergente neutra mostró un comportamiento definido por la estación climática (72,37% en lluvias y 69,67% en pocas lluvias). Los elementos del clima mostraron alta relación con la composición química y se ajustaron modelos lineales de regresión con elevados coeficientes de determinación, superiores a 0,71 en los dos períodos evaluados; las variables lluvias y temperatura máxima fueron las que proporcionaron mayores ajustes. Con el incremento de la edad disminuyó la calidad de la planta, y de los factores climáticos, las precipitaciones y temperatura máxima son las que más afectan la calidad nutritiva de la planta

Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362

Historia de las desigualdades sociales en América Central. Una visión interdisciplinaria, siglos XVIII-XXI

Relación histórica, sobre las desigualdades sociales en América Central, a partir del siglo dieciocho hasta la actualidad, constituyendo una excelente guía que conduce al lector a transitar por nuestra región, por un largo trecho de 200 años aproximadamente, de allí su importancia histórica muy pocas veces abordada con la meticulosidad y seriedad de los enfoques que hacen los autores.UCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Sociales::Centro de Investigaciones Históricas de América Central (CIHAC

Tópicos de marketing

Lograr un equilibrio entre acciones humanas, armonía con la naturaleza, y satisfacer las necesidades del mercado actual sin poner en riesgo aquellos recursos que pudieran precisar las futuras generaciones, es lo importante de impulsar la aplicación del marketing sostenible en las organizaciones. Esto se logra a través de la elaboración de un plan de marketing sostenible que permitirá promover un consumo responsable a través de información clara y oportuna sobre los beneficios personales y sociales que genera la adquisición de productos sostenibles; implantar el reciclado a través de la logística de reversa, procedimiento que origina poca o nula generación de desechos, proporcionar empleos seguros, apoyar al medio ambiente y con responsabilidad social, son algunos beneficios que aporta. El presente capítulo tiene como objetivo proporcionar los principales aspectos que abordan el marketing sostenible, mostrar la importancia de la realización de este marketing para las empresas, así como aportar los pasos para desarrollar un plan de marketing sostenible

Compilación de Proyectos de Investigacion de 1984-2002

Instituto Politecnico Nacional. UPIICS

Comparison of international normalized ratio audit parameters in patients enrolled in GARFIELD-AF and treated with vitamin K antagonists

Vitamin K antagonist (VKA) therapy for stroke prevention in atrial fibrillation (AF) requires monitoring of the international normalized ratio (INR). We evaluated the agreement between two INR audit parameters, frequency in range (FIR) and proportion of time in the therapeutic range (TTR), using data from a global population of patients with newly diagnosed non-valvular AF, the Global Anticoagulant Registry in the FIELD\u2013Atrial Fibrillation (GARFIELD-AF). Among 17\ua0168 patients with 1-year follow-up data available at the time of the analysis, 8445 received VKA therapy (\ub1antiplatelet therapy) at enrolment, and of these patients, 5066 with 653 INR readings and for whom both FIR and TTR could be calculated were included in the analysis. In total, 70\ua0905 INRs were analysed. At the patient level, TTR showed higher values than FIR (mean, 56\ub70% vs 49\ub78%; median, 59\ub77% vs 50\ub70%). Although patient-level FIR and TTR values were highly correlated (Pearson correlation coefficient [95% confidence interval; CI], 0\ub7860 [0\ub7852\u20130\ub7867]), estimates from individuals showed widespread disagreement and variability (Lin's concordance coefficient [95% CI], 0\ub7829 [0\ub7821\u20130\ub7837]). The difference between FIR and TTR explained 17\ub74% of the total variability of measurements. These results suggest that FIR and TTR are not equivalent and cannot be used interchangeably