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11 research outputs found

Clinical implementation of a knowledge based planning tool for prostate VMAT

Author: Andrew Bird
B Wu
C Fiorino
C McGarry
D Good
DW Kim
E Schreibmann
F Buettner
Gareth Webster
Hannah Newman
JM Michalski
JM Michalski
John Sage
Katie Reed
KL Moore
LM Appenzoller
Matthew Brennan
O Nwankwo
R Kierkels
Richard Powis
S Tucker
SL Gulliford
Susan Hinks
T Song
Y Wang
Publication venue: 'Springer Science and Business Media LLC'
Publication date: 01/05/2017
Field of study

Abstract Background A knowledge based planning tool has been developed and implemented for prostate VMAT radiotherapy plans providing a target average rectum dose value based on previously achievable values for similar rectum/PTV overlap. The purpose of this planning tool is to highlight sub-optimal clinical plans and to improve plan quality and consistency. Methods A historical cohort of 97 VMAT prostate plans was interrogated using a RayStation script and used to develop a local model for predicting optimum average rectum dose based on individual anatomy. A preliminary validation study was performed whereby historical plans identified as “optimal” and “sub-optimal” by the local model were replanned in a blinded study by four experienced planners and compared to the original clinical plan to assess whether any improvement in rectum dose was observed. The predictive model was then incorporated into a RayStation script and used as part of the clinical planning process. Planners were asked to use the script during planning to provide a patient specific prediction for optimum average rectum dose and to optimise the plan accordingly. Results Plans identified as “sub-optimal” in the validation study observed a statistically significant improvement in average rectum dose compared to the clinical plan when replanned whereas plans that were identified as “optimal” observed no improvement when replanned. This provided confidence that the local model can identify plans that were suboptimal in terms of rectal sparing. Clinical implementation of the knowledge based planning tool reduced the population-averaged mean rectum dose by 5.6Gy. There was a small but statistically significant increase in total MU and femoral head dose and a reduction in conformity index. These did not affect the clinical acceptability of the plans and no significant changes to other plan quality metrics were observed. Conclusions The knowledge-based planning tool has enabled substantial reductions in population-averaged mean rectum dose for prostate VMAT patients. This suggests plans are improved when planners receive quantitative feedback on plan quality against historical data

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Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.

Author: Aawsaj Y.
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Yanez C.
Yang W.
Yassin N.
Ye G.
Yesantharao P.
Yesilyurt D.
Yetkin G.
Yiallourou A.
Yildirim A.
Yildiz A.
Ying Y.
Yip V.
Yordanov S.
Young R.
Yousof E. A.
Youssef A.
Youssef M.
Yuksel E.
Yurttas C.
Zacharoulis D.
Zafar S. N.
Zakai D.
Zakaria A. D.
Zakaria R.
Zakaria Z.
Zambelli M. F.
Zambon M.
Zamora L.
Zamvar V.
Zani S.
Zanotti S.
Zanus G.
Zapardiel I.
Zarabini A. G.
Zatecky J.
Zegarac M.
Zelic M.
Zeller N.
Zengin A. K.
Zerbib P.
Zervas K.
Zese M.
Zhang H.
Zivanovic M.
Zivkovic M.
Zizzo M.
Zografos C.
Zonta S.
Zorrilla Ortuzar J.
Zourntou S.
Zouzoulas D.
Zubaidi A.
Zullo A.
Publication venue: J Clin Oncol
Publication date: 01/01/2020
Field of study

PURPOSE: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS: This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS: Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION: Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

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Institutional Research Information System University of Turin

Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

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Abad-Motos A.
Abate E.
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Zambelli M. F.
Zambon M.
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Zamvar V.
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Zatecky J.
Zegarac M.
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Zerbib P.
Zervas K.
Zese M.
Zhang H.
Zivanovic M.
Zivkovic M.
Zizzo M.
Zografos C.
Zonta S.
Zorrilla Ortuzar J.
Zourntou S.
Zouzoulas D.
Zubaidi A.
Zullo A.
Publication venue: 'American Society of Clinical Oncology (ASCO)'
Publication date: 01/01/2021
Field of study

PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19–free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19–free surgical pathways. Patients who underwent surgery within COVID-19–free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19–free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score–matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19–free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19–free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

Archivio istituzionale della Ricerca - Università degli Studi di Parma

Use of virtual reality in port implantation to reduce perioperative anxiety and pain: protocol for a randomised controlled pilot trial at a single German university hospital (VIP-trial; DRKS00028508)

Author: Christoph W Michalski
Colette Dörr-Harim
Felix J Hüttner
Hannah Feldmann
Kira C Steinkraus
Lisa S Hunold
Nadir Nasir
Sandra Graf
Publication venue: BMJ Publishing Group
Publication date: 01/09/2023
Field of study

Introduction Intravenous access port implantation is commonly performed under local anaesthesia, which offers advantages such as increased patient satisfaction and resource savings compared with general anaesthesia. However, patients may experience increased perioperative stress and anxiety in the operating room setting without general anaesthesia. Virtual reality (VR) distraction or hypnosis during surgery under local anaesthesia may help patients to auditorily and visually separate from their real environment and engage with a virtual environment through hypnorelaxing guidance. Previous studies suggested that VR hypnosedation may reduce the use of sedatives or general anaesthesia, and may offer additional benefits such as reducing postoperative pain and nausea, and promoting faster patient discharge.Methods and analysis The VIP trial is a randomised controlled pilot trial comparing the usage of VR during port implantation with the current standard of care (local anaesthesia and analgosedation if needed). A total of 120 adult patients are included after screening for eligibility and obtaining informed consent. Patients are randomised preoperatively in a 1:1 ratio to the trial groups. The main outcomes are change of perioperative anxiety and pain. Further outcomes include patient satisfaction and tolerability, perioperative analgesia and sedation, occurrence of postoperative nausea, vomiting and VR sickness symptoms, surgeon’s satisfaction, procedure duration, postoperative complications until postoperative day 30 and patient willingness to hypothetically undergo port implantation again under the same conditions.Ethics and dissemination The VIP trial has been approved by the Ethics Committee of the Medical Faculty of Ulm University (reference number 03/22). If the intervention demonstrates that VR can effectively reduce perioperative anxiety and pain, it may become a novel standard of care to minimise the need for analgosedation or general anaesthesia in port implantation procedures and improve patient outcomes. The results will be submitted to a peer-reviewed journal in the field and will be presented at applicable conferences to ensure rigorous evaluation and access for the academic community.Trial registration number German Clinical Trials Register: DRKS00028508; registration date 15 March 2022; Universal Trial Number: U1111-1275-4995

Directory of Open Access Journals

Novel Bumped Kinase Inhibitors Are Safe and Effective Therapeutics in the Calf Clinical Model for Cryptosporidiosis

Author: Dana P. Betzer
Deborah A. Schaefer
Dustin J. Maly
Erkang Fan
Hannah C. Michalski
Heinrichs
Jennifer A. Zambriski
Kasey L. Rivas
Kayode K. Ojo
Keyloun
Kylie D. Smith
Lynn K. Barrett
Matthew A. Hulverson
Michael W. Riggs
Mondal
Pedroni
Rama S. R. Vidadala
Riggs
Riggs
Samuel L. M. Arnold
Sarah E. Menchaca
Silverlås
Tatipaka
Wenlin Huang
Wesley C. Van Voorhis
Wyatt
Zachary G. Millman
Zambriski
Publication venue: 'Oxford University Press (OUP)'
Publication date
Field of study

Crossref

Inorganic Microchemistry

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Publication venue: 'American Chemical Society (ACS)'
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Field of study

Crossref

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Serralta de Colsa D.
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Sohrabi C.
Song J.
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Souadka A.
Sousa R.
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Spinelli A.
Spriano G.
Spurnic I.
Stavroglou A.
Steel B.
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Tiwari A.
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Vahtsevanos K.
Valle Rubio A.
van der Plas W.
van Ramshorst G. H.
Varazzani A.
Varley I.
Velagapudi S.
Venetis G.
Venn M. L.
Vervoort D.
Vidya R.
Vieira A.
Vimalachandran D.
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Vollkommer T.
Vovola F.
Vucic N.
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Wai K. C.
Walker C.
Walker D.
Walton G.
Warren O. J.
Waseem S.
Wedderburn D.
Wensley F.
Wilkin R. J. W.
Williams T.
Winnand P.
Winter S. C.
Winter S. C.
Winter S. C.
Wolfer S.
Wright N.
Xu M. J.
Yesantharao P.
Ying Y.
Zakai D.
Zarabini A. G.
Zeller N.
Publication venue: 'Wiley'
Publication date: 01/01/2021
Field of study

Background: The aims of this study were to provide data on the safety of head and neck cancer surgery currently being undertaken during the coronavirus disease 2019 (COVID-19) pandemic. Methods: This international, observational cohort study comprised 1137 consecutive patients with head and neck cancer undergoing primary surgery with curative intent in 26 countries. Factors associated with severe pulmonary complications in COVID-19–positive patients and infections in the surgical team were determined by univariate analysis. Results: Among the 1137 patients, the commonest sites were the oral cavity (38%) and the thyroid (21%). For oropharynx and larynx tumors, nonsurgical therapy was favored in most cases. There was evidence of surgical de-escalation of neck management and reconstruction. Overall 30-day mortality was 1.2%. Twenty-nine patients (3%) tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) within 30 days of surgery; 13 of these patients (44.8%) developed severe respiratory complications, and 3.51 (10.3%) died. There were significant correlations with an advanced tumor stage and admission to critical care. Members of the surgical team tested positive within 30 days of surgery in 40 cases (3%). There were significant associations with operations in which the patients also tested positive for SARS-CoV-2 within 30 days, with a high community incidence of SARS-CoV-2, with screened patients, with oral tumor sites, and with tracheostomy. Conclusions: Head and neck cancer surgery in the COVID-19 era appears safe even when surgery is prolonged and complex. The overlap in COVID-19 between patients and members of the surgical team raises the suspicion of failures in cross-infection measures or the use of personal protective equipment. Lay Summary: Head and neck surgery is safe for patients during the coronavirus disease 2019 pandemic even when it is lengthy and complex. This is significant because concerns over patient safety raised in many guidelines appear not to be reflected by outcomes, even for those who have other serious illnesses or require complex reconstructions. Patients subjected to suboptimal or nonstandard treatments should be carefully followed up to optimize their cancer outcomes. The overlap between patients and surgeons testing positive for severe acute respiratory syndrome coronavirus 2 is notable and emphasizes the need for fastidious cross-infection controls and effective personal protective equipment

Archivio istituzionale della Ricerca - Università degli Studi di Parma

PubliCatt

Archivio Istituzionale della Ricerca- Università degli Studi di Foggia

Delaying surgery for patients with a previous SARS-CoV-2 infection

Author: A A Ali Karar
A A Kerawala
A A Marra
A Abad Gurumeta
A Abad-Motos
A Abdelmajeed
A Abdelrahman
A Abdelsamed
A Abdulkareem
A Aboelkassem Ibrahim
A Abouassi
A Abreu da Silva
A Abubakar
A Acher
A Aderombi
A Adeyeye
A Adiamah
A Aggarwal
A Aghayeva
A Agnes
A Agrawal
A Ahmeidat
A Aimé
A Ajlan
A Al-Habib
A Al-Mohammad
A Al-Mukhtar
A Aladeojebi
A Alamri
A Alanbuki
A Alatar
A Alburakan
A Alfaro-Goldaracena
A Alhamed
A Alhefdhi
A Almeciga
A Almeida
A Alomair
A Alonso Poza
A Alsaif
A Anastasi
A Antic
A Anzak
A Aprile
A Arminio
A Arulanantham
A Askari
A Asqalan
A Athanasiou
A Ayhan
A Ayman
A Ayubi
A Azizi
A B Martins
A Bacon
A Baker
A Balakrishnan
A Bandiera
A Banerjee
A Barrabe
A Beamish
A Bellacci
A Belli
A Belvedere
A Benkabbou
A Bhalla
A Bhangu
A Billè
A Bin Nasser
A Biondi
A Blatt
A Blazquez Martin
A Boddy
A Bokhari
A Bondurri
A Boulton
A Boutall
A Branquinho
A Brunelli
A Brunt
A Bruscino
A Budacan
A Burahee
A Böttcher
A C Almeida
A C Deus
A C Roslani
A C Soares
A C Vieira Paiva Lopes
A Caiado
A Camillo
A Canas-Martinez
A Cano
A Carabias
A Chandock
A Charalabopoulos
A Che Jusoh
A Chebaro
A Chessa
A Chiappini
A Chitul
A Choudhry
A Chowdhury
A Colquhoun
A Conesa
A Cordova
A Costanzi
A Cotoia
A Cotter
A Crichton
A Cuadrado-García
A Currie
A Cvetkovic
A D Bueno Cañones
A D Rajgor
A D Zakaria
A D'Amore
A D'Urso
A Daly
A Davies
A Day
A De Gea Rico
A De Manzoni Garberini
A De Pablo García-Cuenca
A De Troia
A De Virgilio
A Dehal
A Desai
A Di Bartolomeo
A Di Bella
A Di Somma
A Diamantis
A Doyle
A Durrani
A E Arikan
A E Sherif
A Eastmond
A El Ouahabi
A Elawad
A Eldaly
A Elhamshary
A Esposito
A Esteban
A Ezanno
A Fadzli
A Fagotti
A Fancellu
A Farsi
A Faustino
A Fazenda
A Fernández-López
A Ferrero
A Ferrés
A Fiorini
A Fisher
A Fletcher
A Fowler
A Fox
A Frampton
A Frankel
A Frati
A Freitas
A Frena
A Fuson
A G Carta
A G Zarabini
A Gabre-Kidan
A Gagliano
A Gainza
A Gatti
A Gattolin
A Gaunt
A Geddes
A Gegúndez Simón
A Ghanbari
A Ghannam
A Giaglaras
A Gianni
A Giblin
A Gillis
A Gklavas
A Glencer
A Gomes da Costa
A Gori
A Goyal
A Gronchi
A Gueutier
A Guglielmi
A Guimarães
A Gupta
A Gutierrez Calvo
A Gvaramadze
A Gómez-Pedraza
A H Hussain
A H Khan
A Habeeb
A Hainsworth
A Hamad
A Hannah
A Hanson
A Harky
A Hasenburg
A Hawkins
A Haynes
A Haynes
A Henry
A Herman
A Hernández Gutierrez
A Heuer
A Hmedat
A Hogan
A Hunt
A I Gutiérrez Fernández
A I Kilani
A I Soriano
A I Tercero-Uribe
A Ibrahim
A Ionescu
A Jah
A Jain
A Jamal
A Jibril
A Jiménez
A Joshi
A Jotic
A K Ali
A K Andrade
A K Lala
A K Scafa
A K Zengin
A Kahn
A Kamocka
A Kanatas
A Kappenberger
A Karamarkovic
A Karim
A Kattakayam
A Kaufmann
A Kawai
A Kent
A Khajuria
A Khan
A Khoja
A Kirk
A Kisiel
A Kler
A Kocataş
A Koh
A Kolias
A Kollàr
A Kolusarı
A Kourdouli
A Kouyoumdjian
A Kredan
A Kumar
A Königsrainer
A L De Oliveira López
A L Ebbehøj
A L Picardo
A Laforest
A Lagares
A Laios
A Laird
A Landaluce-Olavarria
A Lanzon
A Larentzakis
A Lauretta
A Lim
A Loayza
A Loehrer
A Lopez Abad
A Louvrier
A Lovece
A Lowery
A Lyons
A Lázaro
A López Campillo
A M Abbas
A M Baietti
A M Castaño-Leon
A M Correia
A M Lacy
A M Majbar
A M Minaya Bravo
A M Ntziovara
A M Pathanki
A M Perrone
A M Scanu
A Macchi
A Madhavan
A Madkhali
A Maffioli
A Maffuz-Aziz
A Maghrabi
A Maiga
A Majkowska
A Mansuri
A Mantevas
A Marano
A Marchbank
A Marco Garrido
A Margalit
A Martin-Ucar
A Martinez German
A Marçal
A Mashat
A Maw
A McCanny
A Mccarthy
A McLennan
A McMillan
A Melo
A Menon
A Merchan
A Merdrignac
A Miljković
A Millan
A Mingoli
A Minicozzi
A Mirabella
A Modabber
A Mohammad
A Moro
A Morris
A Morsi
A Morton
A Mosca
A Moumen
A Muratore
A Mustafa
A N Sanli
A Nabil
A Nakas
A Nawawi
A Nobre Pinto
A Nogués
A Oar
A Oliveira
A Osorio
A Otero
A Ovaitt
A P Ferreira Pinto
A P Pezzuto
A Parello
A Parente
A Parseliunas
A Patel
A Patel
A Paunovic
A Pearce
A Pereira
A Pereira-Neves
A Peryt
A Petrillo
A Piras
A Pisani Ceretti
A Pisanu
A Polydorou
A Popoola
A Porcu
A Provozina
A Pucar
A Pérez Núñez
A Qasem
A Quennell
A Qureshi
A Ramachandran
A Ramos Bonilla
A Ramwell
A Ribeiro
A Rizzi
A Robinson
A Robson
A Rodolakis
A Rodrigues
A Rodriguez Fraga
A Rogers
A Rogers
A Romero de Diego
A Rowcroft
A Ruivo
A Ruiz Escobar
A Ruzzenente
A S Bodla
A S Coonar
A S Crugnale
A S Memon
A S Mohamed Sidek
A S Yahaya
A Sabry
A Sachdeva
A Sagnotta
A Said Bayazeed
A Salamah
A Salazar
A Saleem
A Samih
A Samir Abdelaal
A Samkari
A Samy
A Santoro
A Sanz Larrainzar
A Saratziotis
A Sarin
A Sayasneh
A Scalabre
A Schache
A Seguin-Givelet
A Seleim
A Sgrò
A Shabana
A Sharkey
A Sharma
A Sheel
A Shenfine
A Sherif
A Shuwayyah
A Singh
A Soares
A Solth
A Souadka
A Spinelli
A Ssentongo
A Stanimirovic
A Stavroglou
A Stefanovic
A Stepanyan
A Subocius
A Sultana
A Sutherland
A Syllaios
A Sánchez-Pernaute
A Taddei
A Taibi
A Tailor
A Tang
A Tedde
A Thomas
A Thompson
A Tojal
A Tooulias
A Torne
A Torres
A Townson
A Trivic
A Tufo
A Turnbull
A Urbani
A Urbieta
A Usai
A Valente da Costa
A Vallance
A Valle Rubio
A Varazzani
A Vazquez Fernandez
A Vezakis
A Vieira
A Vignali
A Vitali
A Wali
A Wilkins
A Wimmer
A Woodham
A Y Azzam
A Yiallourou
A Yıldırım
A Yildiz
A Youssef
A Zubaidi
A Zullo
A Älgå
Abd Elazeem Has
Abhinav Tiwari
Abigail Vallance
Adesoji Ademuyiwa
Adesoji O Ademuyiwa
Adrian Marchbank
Ahmad Qureshi
Akshay Patel
Alan McNeill
Alessandro Brunelli
Alessandro Gronchi
Alex Alamri
Alex Wilkins
Alexandra Colquhoun
Alexis P Arnaud
Aman S Coonar
Amanpreet Brar
Ana Minaya-Bravo
Ana Minaya-Bravo
Ana Minaya-Bravo
Ana Minaya-Bravo
Anant Desai
Anant Desai
Andreas A Schnitzbauer
Andreas K Demetriades
Andrew G Schache
Andrew Knight
Andrew Loehrer
Andrew Schache
Andrey Litvin
Aneel A Bhangu
Aneel A Bhangu
Aneel Bhangu
Angelos Kolias
Angelos Kolias
Anna Fagotti
Antonino Spinelli
Antonio Ramos-De la Medina
April C Roslani
Arda Isik
Arnav Agarwal
B A Fahey
B Al-Sarireh
B Albi Martin
B Alhassan
B Ayub
B B Ozmen
B Baca
B Bakmaz
B Banky
B Barmayehvar
B Barrat
B Bartalucci
B Bozkırlı
B Brown
B Caimari
B Challacombe
B Chumbinho
B Cimenoglu
B Cirillo
B Citgez
B Collard
B Costeira
B Cros
B Davidson
B De Andrés Asenjo
B De Simone
B Devauchelle
B Dias
B Diéguez
B Díaz-Feijoo
B El Ahmadi
B Gil Ibañez
B Giray
B Gricks
B Griffiths
B Grotenhuis
B Gális
B Göksoy
B J Mehigan
B Jayasankar
B Johnston
B Kajmaković
B Keeler
B Kidane
B Knowles
B Kocer
B Kotlar
B Kovacevic
B Lamb
B Le Roy
B Lieske
B Malgras
B Manku
B Mantoglu
B Martin-Perez
B McAree
B Narice
B Nunez-Garcia
B Patrício
B Pramodana
B Pérez-Saborido
B Rai
B S Kamera
B S Ong
B Seeliger
B Sheu
B Soyak
B Steel
B Swinson
B Tadic
B Thakur
B Ugarte-Sierra
B Vieira
B Vieira
B Wadham
Bandara Gbk
Benjamin Lamb
Brett E Dawson
Brittany K Bankhead-Kendall
C A Espinosa
C A Guariglia
C Abatini
C Agostini
C Allemand
C Alurralde
C Anthoulakis
C Arican
C Ashmore
C Aydin
C Azevedo
C B Kulle
C Baker
C Baldi
C Barry
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C Bassi
C Baía
C Belluco
C Bergamini
C Bescós
C Beyrne
C Bezede
C Bisset
C Boeker
C Bong
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C Burgess
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C C Foo
C Cagigas Fernandez
C Camacho
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C Castro Ruiz
C Chan
C Chan
C Chan
C Checcucci
C Christou
C Collins
C Corbellini
C Corvera
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C Cullinane
C Cunha
C Dawson
C Delimpalta
C Denet
C Di Martino
C Donohue
C Eiriz Fernandez
C Evans
C Evans
C Eveno
C F Feo
C Ferreira
C Ferron
C Fitzgerald
C Fleming
C Fotopoulou
C Frattaruolo
C Freyschlag
C G Gil
C G Mitrofan
C Gambacciani
C Gan
C Gaskill
C Gemmell
C Gill
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C Gracia-Roche
C Grieco
C Grundy
C Guerci
C Halloran
C Hammer
C Hardie
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C Hill
C Houlden
C J Gómez Díaz
C Jelley
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C Kalfountzos
C Kamphues
C Kang
C Kelty
C Kloppers
C Knowles
C Konstantinou
C Kontovounisios
C Korais
C Kurze
C Kuzmanovic
C L Roland
C Langdon
C Leal
C Leonardo
C Lewis-Lloyd
C Lima da Silva
C Linari
C Loh
C Long
C Lopes
C Louis-Sylvestre
C M Chiesa-Estomba
C Magee
C Marchitelli
C Martí
C Martínez Chicote
C Martínez-Pinedo
C McDonald
C McNaught
C Mellor
C Michalski
C Millward
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C Mulligan
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C Olona
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C Price
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C Redondo
C Rey Valcarcel
C Riediger
C Riley
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C Roy
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C Sanchez Rodriguez
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Christian Freyschlag
Christina Fotopoulou
Cioffi Spb
Conor S Jones
Constantine Halkias
Costa Mjma
D A Raptis
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D M Donati
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D Sapre
D Sasia
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D Serralta de Colsa
D Shrestha
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D Snee
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D Stevic
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D T María Dolores
D Tartaglia
D Tatsis
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D Thompson
D Townend
D Tsolakidis
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Dale Vimalachandran
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Daniel Cox
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David Moszkowicz
Dejan Radenkovic
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Derek Alderson
Dhruv Ghosh
Dinesh Thekinkattil
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U Akgor
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Á De la Hoz Rodríguez
Á Fernández Camuñas
É Ryan
Ž Grubač
А Камалов
Publication venue: 'Wiley'
Publication date: 01/01/2020
Field of study

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Head and neck cancer surgery during the COVID-19 pandemic: An international, multicenter, observational cohort study

Author: Abbott T
Abbott Tom EF
Abdallah M
Abdelkarem MM
Abdulkareem A
Abellán M
Abou Chaar MK
Abouassi A
Abur PP
Achalandabaso Boira M
Adamina Michel
Adamoli L
Ademuyiwa Adesoji O
Agarwal Arnav
Aguilera Lorena Maria
Ahad S
Akeel N
Al Habes H
Al-Masri M
Al-Najjar H
Alakaloko Felix
Alameer Ehab
Alawneh F
Albertsmeiers Markus
Alcaide Matas F
Alderson Derek
Alexoudi V
Alfaro-Goldaracena A
Alhassan B
Alhefdhi A
Alintoprak F
Alkarak S
Allison J
Almasri M
Almeida A
Alomair A
Alonso-Lamberti L
Alotaibi N
Alqannas M
Alresaini F
Alsaif A
Alsalamah R
Alsaraireh O
Alser Osaid
Alshaar Muhammad
Alshahrani M
Alsharif F
Alshryda Sattar
Alsobhi S
Alvarez MR
Alyami M
Alzamanan M
Ameerally P
Ansarin M
Antic S
Antoniades K
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Chiesa-Estomba CM
Choudhry A
Christensen Peter
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Chu F
Chumbinho B
Cicconi Silvia
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Consorti G
Cope D
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De Virgilio A
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Deligiannidis D
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Desai Anant
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Djurisic I
Domínguez I
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Ferraz I
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Ferron C
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Figueiredo de Barros I
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Heritage Emily
Hernandez Bartolome MA
Hisham Intisar
Ho Michael Wing Sung
Ho Michael WS
Ho MWS
Houston R
Howe D
Huang L
Humphries S
Hutchinson Peter J
Hwang Shelley
Hölzle F
Ibrahim A
Idle M
Inic Z
Ioannidis O
Ionescu A
Irune E
Isik Arda
Jackson Richard
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Jariod Ferrer UM
Jeftic N
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Jenkinson Michael D
Jenny H
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Jimenez Toscano M
Jimenez V
Jokic V
Jones Conor S
Jones T
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Jotic A
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Kahn A
Kalaitsidou I
Kalavrezos N
Kam da Silva Andrade A
Kamarajah Sivesh K
Kanatas A
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Keatley James M
Kent A
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Minaya-Bravo Ana
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van der Plas Willemijn
van Ramshorst Gabrielle H
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Vervoort D
Vidya Raghavan
Vieira A
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Vo UG
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Waseem S
Wedderburn Duane
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Wilkin Richard JW
Williams T
Winnand P
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Winter Stuart C
Winter Stuart C
Wolfer S
Wright Naomi
Xu MJ
Yesantharao P
Ying Y
Zakai D
Zarabini AG
Zeller N
Çapoğlu R
Çolak E
Öfner D
Šimko K
Publication venue: 'Wiley'
Publication date: 01/01/2020
Field of study

University of Liverpool Repository

Serveur académique lausannois

Archivio istituzionale della ricerca - Alma Mater Studiorum Università di Bologna

Oxford University Research Archive

Queen Mary Research Online

University of Dundee Online Publications

White Rose Research Online

Archivio istituzionale della ricerca - Università di Modena e Reggio Emilia

University of Melbourne Institutional Repository

Archivio istituzionale della ricerca - Università di Padova

Archivio istituzionale della ricerca - Università di Palermo

Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic.

Author: Aawsaj Y
Abad Gurumeta A
Abad-Motos A
Abate E
Abatini C
Abbadessa F
Abbas AM
Abbassi-Ghadi N
Abbott D
Abbott T
Abbott TEF
Abd Elazeem HAS
Abdalla M
Abdallah M
Abdelaal SA
Abdeldayem H
Abdelkarem MM
Abdelkarim M
Abdelmajeed A
Abdelrahman A
Abdelrahman S
Abdelsamed A
Abdou M
Abdulkareem A
Abdulwahed E
Abdur-Rahman L
Abel MK
Abellan M
Abosamak NE
Abou Chaar MK
Abou-Khalil J
Abouassi A
Aboulkassem H
Abreu da Silva A
Abu Za'nouneh FJ
Abu J
Abu-Nayla I
Abubakar A
Abukhalaf S
Acebes Garcia F
Achalandabaso Boira M
Acher A
Acrich E
Adamina M
Adamina M
Adamoli L
Addae-Boateng E
Ademuyiwa AO
Aderombi A
Adeyeye A
Adiamah A
Adishesh M
Agapov M
Agarwal A
Aggarwal A
Aghayeva A
Agilinko J
Agnes A
Agostini C
Agoston P
Agrawal A
Agresta F
Aguado H
Aguzzoli L
Ahad S
Ahmadi N
Ahmed NR
Ahmeidat A
Ahn JH
Aiken T
Aime A
Ajlan A
Akalin M
Akaydin E
Akeel N
Akgor U
Akhtar MA
Akilli H
Akin E
Akkour K
Akkulak M
Akmenkalne L
Al Abdallah M
Al Abdel S
Al Awwad S
Al Habes H
Al Maadany FS
Al Raddadi R
AL Sayed M
Al-Habib A
Al-Habsi R
Al-Ishaq Z
Al-Khayal K
Al-Masri M
Al-Mohammad A
Al-mukhtar A
Al-Najjar H
Al-omishy H
Al-Sarireh B
Al-Tamimi Y
Alaa S
AlAamer O
Aladeojebi A
Alakaloko F
Alam F
Alam N
Alam R
Alameer E
Alamri A
Alamri A
Alanbuki A
Alatar A
Alawneh F
Alazawi D
Albertsmeier M
Albertsmeiers M
Albi Martin B
Alburakan A
Alcaide Matas F
Alconchel F
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Aldecoa Ansorregui I
Alderson D
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Aleksic L
Alemanno G
Alexoudi V
Alfaro-Goldaracena A
Alfieri S
Alga A
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Alhalal H
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Alhefdhi A
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Buarque IL
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Bueno Canones AD
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Cagigal Ortega EP
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Caja Vivancos P
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Campbell W
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Canhoto C
Cano A
Cano-Valderrama O
Canonico G
Canotilho R
Cantalejo Diaz M
Cao H
Capelli P
Capezzuoli L
Capitan-Morales L
Capizzi V
Capoglu R
Capolupo GT
Carabias A
Caram EL
Carannante F
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Cardoso P
Caricato M
Carrano FM
Carrasco Prats M
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Carta AG
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Castillejos-Molina RA
Catala Bauset JC
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Cato LD
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Cavalle Busquets P
Cayetano Paniagua L
Cazador Labat M
Cecchini L
Cecconello I
Cecire J
Celebi F
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Ceretti PA
Cervellera M
Cervera I
Ceyhan GO
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Chai AKW
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Chakrabortee S
Challacombe B
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Charlton G
Chase T
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Checcucci C
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Chen S
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Cheung LK
Chevallay M
Chew D
Chia Z
Chiappini A
Chiarella V
Chiarugi M
Chidambaram S
Chiesa-Estomba CM
Chiozza M
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Choi D
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Choolani Bhojwani E
Choong P
Chopra S
Choudhry A
Choudhury J
Chouillard E
Chowdhry MF
Chowdhury A
Choynowski M
Christensen P
Christensen P
Christidis P
Christoforidis D
Christou C
Chrysos E
Chu F
Chumbinho B
Chung E
Cianflocca D
Ciccarone F
Cicerchia PM
Cimenoglu B
Cintas Catena J
Cioffi SPB
Ciofic E
Cipriani R
Cirillo B
Cirocchi N
Cisternino G
Citgez B
Citterio D
Clark J
Claro M
Clatworthy S
Clifford R
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Cocozza E
Coe P
Coffey JC
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Colak E
Colao Garcia L
Colino M
Collaborative C
Collard B
Colledan M
Collera P
Colletti G
Collins C
Collis J
Colloc T
Colombari RC
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Colombo F
Colquhoun A
Colquhoun A
Combellack T
Comini LV
Conesa A
Confalonieri M
Conlon K
Connelly T
Connolly EM
Consorti G
Conti L
Conti L
Contis I
Cool P
Coonar AS
Coonar AS
Cope D
Corbellini C
Corbin S
Cordera F
Cordova A
Corless K
Correia de Sa T
Correia AM
Correia J
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Corrigan M
Corte Real J
Corvera C
Cosentino ML
Cosimelli M
Cossu ML
Costa Santos D
Costa M
Costa MJMA
Costanzi A
Costeira B
Costigan F
Cotoia A
Cotsoglou C
Cotte E
Cotter A
Cottu P
Coughlin P
Cox D
Coza I
Cozza V
Crank M
Creavin B
Cribb G
Crichton A
Cristian D
Cros B
Crugnale AS
Cuadrado-Garcia A
Cukier M
Cullinane C
Cullivan O
Cuming T
Cunha C
Cunha MF
Cunha MF
Cunha R
Cunningham R
Curl-Roper T
Currie A
Cvetkovic A
Cymes W
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D'Amore A
D'Andrea G
D'Angelo G
D'Ugo D
D'Ugo S
D'Urso A
Dafnios N
Daiko H
Dainius E
Dakpe S
Daliya P
Daly A
Danias N
Daniels I
Davidson B
Davidson GH
Davies A
Davies E
Davies E
Davies RJ
Dawe N
Dawson BE
Dawson C
Day A
De Andres Asenjo B
De Andres Olabarria U
De Barros J
De Berardinis R
De Bree R
De Cicco R
De Crescenzo E
De Graaff M
De Iaco P
De la Hoz Rodriguez A
De la Rosa Abaroa MA
De Lacy FB
De Miguel Ardevines MDC
De Nardi P
De Oliveira Lopez AL
De Pablo Garcia-Cuenca A
De Palma G
De Pastena M
De Simone B
De Simone V
de Solorzano Aurusa OFJ
De Sousa X
De Toma G
De Troia A
De Vincenti R
De Virgilio A
Dehal A
Del Campo Martin M
Del Valle E
Delgado Fernandez J
Deligiannidis D
Delimpalta C
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Delrio P
Demetriades AK
Demir H
Demirhan R
Demyttenaere S
Denet C
Dent H
Depalma N
Derkaoui Hassani F
Derksen T
Desai A
Desai A
Desai A
Desio M
Deus AC
Devauchelle B
Devezas V
Devine M
Di Bartolomeo A
Di Bella A
Di Candido F
Di Chiara F
Di Franco G
Di Giuseppe M
Di Martino C
Di Martino M
Di Marzo F
Di Saverio S
Di Saverio S
Di Somma A
Di Taranto G
Diamantis A
Dias B
Diaz Del Gobbo R
Diaz Pena P
Diaz Perez D
Diaz-Feijoo B
Dickson K
Dieguez B
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Diez-Valladares L
Dijan E
Dikicier E
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Dincer HA
Distler M
Divya GS
Dixon J
Djurisic I
Dokic M
Domingo S
Domingues JC
Dominguez I
Dominguez-Rosado I
Donati D
Donati DM
Dondi G
Donlon N
Donohue C
Dowdy S
Doyle A
Drake T
Drake TM
Drubay V
Duchalais E
Dudi-Venkata NN
Duff S
Dulgeroglu O
Dumitra S
Dumitra S
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Dunning J
Duque M
Duque-Mallen V
Duran Ballesteros M
Duran-Valles F
Durrani A
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Dwidar O
Dzamic Z
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Eastmond A
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Economopoulou P
Edmond M
Edmondson R
Edwards J
Edwards J
Edwards JG
Efthimiou M
Egan R
Egbeare D
Egbuchulem IK
Egoroff N
Eiriz Fernandez C
El Aamrani M
El Abbadi N
El Ahmadi B
El Bouazizi Y
El Ouahabi A
El-sayed I
Elawad A
Elayyan M
Elazzazy E
Elbe P
Eldaly A
Elena GDCR
ElFiky M
Elghazaly MS
Elhadi M
Elhamshary A
Elhoseiny M
Elhusseini M
Elkadi H
Elkaffas SMMM
Elkhayat H
Elliott JA
Elliott M
Ellojli I
Elmoslemany T
Elnemr M
Elqasabi MS
Elsey E
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Elsherbini I
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Emile S
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Emmanuel K
Emslie K
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Ensenat Nora J
Ergun S
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Escartin J
Escobar P
Escola D
ESCP ESC
Esene I
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Eskander P
Eskinazi D
Espin-Basany E
Espino Segura-Illa M
Espinosa CA
Espitalier F
Esposito A
Esposito G
Essam E
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Estaire Gomez M
Esteban Agusti E
Esteban Sinovas O
Esteban A
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Evans J
Evans JP
Evans JP
Evans RPT
Evans S
Eveno C
Evoy D
Eweda M
Ezanno A
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Fabregas N
Fadzli A
Fagotti A
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Fahey BA
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Falcon GM
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Fancellu A
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Farma J
Farnesi F
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Faulkner G
Faustino A
Fayed Y
Fazenda A
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Federico P
Federico PNS
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Felli E
Fenton M
Feo CF
Feo CV
Fernandes U
Fernandes V
Fernandez Bernabe P
Fernandez Camunas A
Fernandez Pablos FJ
Fernandez Rodriguez P
Fernandez M
Fernandez PV
Fernandez-Lopez A
Fernando D
Ferrari F
Ferrari M
Ferrario L
Ferraz I
Ferreira Pinto AP
Ferreira C
Ferreli F
Ferrero A
Ferrero S
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Ferron C
Fidalgo H
Fidelis L
Figari M
Figueiredo de Barros I
Findlay L
Finnegan L
Fiore M
Fiore M
Fiore M
Fiore M
Fiori E
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Firat N
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Fitzgerald C
Fitzgerald JE
Fitzjohn H
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Flavin M
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Fleming J
Fletcher A
Flindall I
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Foley D
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Fong R
Fonseca F
Fonsi GB
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Fontana T
Foo CC
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Ford S
Ford S
Fordington S
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Fortuna L
Fossett R
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Foulkes R
Fountain D
Fountain DM
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Frampton A
Franco G
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Freitas A
Frena A
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Freyschlag C
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Frio F
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Fritzmann J
Frongia F
Fruscio R
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Galliamov E
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Gallo G
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Gambacciani C
Gan C
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Garcia Alonso M
Garcia Egea J
Garcia Escudero D
Garcia Gutierrez JJ
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Garcia Perez JM
Garcia Pineda V
Garcia Porcel VJ
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Garcia Romero E
Garcia Santos EP
Garcia Senorans PM
Garcia Septiem J
Garcia Soria V
Garcia Villayzan JE
Garcia JS
Garcia PM
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Garcia-Moreno Nisa F
Garcia-Quijada J
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Gata V
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Gavalda Pellice MGP
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Gerchunoff JI
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Glasbey JC
Glasbey JC
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Gracia-Roche C
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Grau-Talens EJ
Graystone J
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Grieco C
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Griffiths E
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Griffiths O
Grigoroiu M
Grilo JV
Grimaldi DMS
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Grimley E
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Guariglia CA
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Kalfountzos C
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Kamburoglu MB
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Kanemitsu Y
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Kara Y
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Karaman E
Karamarkovic A
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Sampaio da Novoa Gomes Miguel II
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Publication venue: Br J Surg
Publication date: 11/11/2020
Field of study

BACKGROUND: Surgical services are preparing to scale up in areas affected by COVID-19. This study aimed to evaluate the association between preoperative SARS-CoV-2 testing and postoperative pulmonary complications in patients undergoing elective cancer surgery. METHODS: This international cohort study included adult patients undergoing elective surgery for cancer in areas affected by SARS-CoV-2 up to 19 April 2020. Patients suspected of SARS-CoV-2 infection before operation were excluded. The primary outcome measure was postoperative pulmonary complications at 30 days after surgery. Preoperative testing strategies were adjusted for confounding using mixed-effects models. RESULTS: Of 8784 patients (432 hospitals, 53 countries), 2303 patients (26.2 per cent) underwent preoperative testing: 1458 (16.6 per cent) had a swab test, 521 (5.9 per cent) CT only, and 324 (3.7 per cent) swab and CT. Pulmonary complications occurred in 3.9 per cent, whereas SARS-CoV-2 infection was confirmed in 2.6 per cent. After risk adjustment, having at least one negative preoperative nasopharyngeal swab test (adjusted odds ratio 0.68, 95 per cent confidence interval 0.68 to 0.98; P = 0.040) was associated with a lower rate of pulmonary complications. Swab testing was beneficial before major surgery and in areas with a high 14-day SARS-CoV-2 case notification rate, but not before minor surgery or in low-risk areas. To prevent one pulmonary complication, the number needed to swab test before major or minor surgery was 18 and 48 respectively in high-risk areas, and 73 and 387 in low-risk areas. CONCLUSION: Preoperative nasopharyngeal swab testing was beneficial before major surgery and in high SARS-CoV-2 risk areas. There was no proven benefit of swab testing before minor surgery in low-risk areas

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Crossref

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UCL Discovery

eScholarship - University of California

Archivio istituzionale della ricerca - Alma Mater Studiorum Università di Bologna

Apollo (Cambridge)

Bern Open Repository and Information System (BORIS)

Queen Mary Research Online

White Rose Research Online

Archivio istituzionale della ricerca - Università di Palermo