Mine Clearance Techniques and Technologies for Effective Humanitarian Demining

To improve mine clearance performance and to enhance safety of demining personnel, there is a need for efficient humanitarian mine action equipment. Accurate and reliable mine detection techniques and technologies capable of area detection and clearance are crucial for successful demining

Pre-Harvest and Post-Harvest Techniques for Plant Disease Detections

As the agriculture industry is growing fast, many efforts are introduced to ensure a high quality of produce. Diseases and defects found in plants and crops affect greatly the agriculture industry. Hence, many techniques and technologies have been developed to help solve or reduce the impact of plant diseases. Imagining analysis tools and gas sensors are becoming more frequently integrated into smart systems for plant disease detection. Many disease detection systems incorporate imaging analysis tools and VOC (Volatile Organic Compound) profiling techniques to detect early symptoms of diseases and defects of plants, fruits, and vegetative produce. These disease detection techniques can be further categorized into two main groups: preharvest disease detection and postharvest disease detection techniques. This paper aims to introduce the available disease detection techniques and to compare them with the latest innovative smart systems that feature visible imaging, hyperspectral imaging, and VOC profiling. In addition, this paper considers the efforts to automate imaging techniques to help accelerate the disease detection process. Different approaches are analyzed and compared in terms of work environment, automation, implementation, and accuracy of disease identification along with the future evolution perspective in this field

Robot ontologies for sensor- and Image-guided surgery

Robots and robotics are becoming more com- plex and flexible, due to technological advancement, improved sensing capabilities and machine intelligence. Service robots target a wide range of applications, relying on advanced Human–Robot Interaction. Medical robotics is becoming a leading application area within, and the number of surgical, rehabilitation and hospital assistance robots is rising rapidly. However, the complexity of the medical environment has been a major barrier, preventing a wider use of robotic technology, thus mostly teleoperated, human-in-the-loop control solutions emerged so far. Providing smarter and better medical robots requires a systematic approach in describing and translating human processes for the robots. It is believed that ontologies can bridge human cognitive understanding and robotic reasoning (machine intelligence). Besides, ontologies serve as a tool and method to assess the added value robotic technology brings into the medical environment. The purpose of this paper is to identify relevant ontology research in medical robotics, and to review the state-of-the art. It focuses on the surgical domain, fundamental terminology and interactions are described for two example applications in neurosurgery and orthopaedics

Ontologies for Industry 4.0

The current fourth industrial revolution, or ‘Industry 4.0’ (I4.0), is driven by digital data, connectivity, and cyber systems, and it has the potential to create impressive/new business opportunities. With the arrival of I4.0, the scenario of various intelligent systems interacting reliably and securely with each other becomes a reality which technical systems need to address. One major aspect of I4.0 is to adopt a coherent approach for the semantic communication in between multiple intelligent systems, which include human and artificial (software or hardware) agents. For this purpose, ontologies can provide the solution by formalizing the smart manufacturing knowledge in an interoperable way. Hence, this paper presents the few existing ontologies for I4.0, along with the current state of the standardization effort in the factory 4.0 domain and examples of real-world scenarios for I4.0.Peer ReviewedPostprint (published version

A review and comparison of ontology-based approaches to robot autonomy

Within the next decades, robots will need to be able to execute a large variety of tasks autonomously in a large variety of environments. To relax the resulting programming effort, a knowledge-enabled approach to robot programming can be adopted to organize information in re-usable knowledge pieces. However, for the ease of reuse, there needs to be an agreement on the meaning of terms. A common approach is to represent these terms using ontology languages that conceptualize the respective domain. In this work, we will review projects that use ontologies to support robot autonomy. We will systematically search for projects that fulfill a set of inclusion criteria and compare them with each other with respect to the scope of their ontology, what types of cognitive capabilities are supported by the use of ontologies, and which is their application domain.Peer ReviewedPostprint (author's final draft

Mutations and Deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascades Which Alter Therapy Response

The Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades are often activated by genetic alterations in upstream signaling molecules such as receptor tyrosine kinases (RTK). Certain components of these pathways, RAS, NF1, BRAF, MEK1, DUSP5, PP2A, PIK3CA, PIK3R1, PIK3R4, PIK3R5, IRS4, AKT, NFKB1, MTOR, PTEN, TSC1, and TSC2 may also be activated/inactivated by mutations or epigenetic silencing. Upstream mutations in one signaling pathway or even in downstream components of the same pathway can alter the sensitivity of the cells to certain small molecule inhibitors. These pathways have profound effects on proliferative, apoptotic and differentiation pathways. Dysregulation of components of these cascades can contribute to: resistance to other pathway inhibitors, chemotherapeutic drug resistance, premature aging as well as other diseases. This review will first describe these pathways and discuss how genetic mutations and epigenetic alterations can result in resistance to various inhibitors