13 research outputs found

    Elites in the UK: new approaches to contemporary class divisions

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    Elites in the uk: new approaches to contemporary class divisions The aim of this article is to demonstrate the “new” elites emerging in the uk amidst the economic, political and social context of neoliberalism. To do this, we examine the works of Mike Savage regarding what elite studies have meant for contemporary forms of social division. Using data from the Great British Class Survey, the author underlines sociological elements that are central to the composition of this financialised elite. We describe cleavages in terms of social mobility, education, location and politicization that are generated through the concentration of distinct types of capital (economic, social and cultural). Departing from the specific context of Great Britain, we intend to contribute to the development of a sociology of elites, through a discussion of both new perspectives and the limits and possibilities of treating different geographic, political and social contexts

    The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study

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    AIM: The SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery. METHODS: This was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin. RESULTS: Overall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P < 0.001). After adjustment, delay was not associated with a lower rate of complete resection (OR 1.18, 95% CI 0.90-1.55, P = 0.224), which was consistent in elective patients only (OR 0.94, 95% CI 0.69-1.27, P = 0.672). Longer delays were not associated with poorer outcomes. CONCLUSION: One in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease

    Elites no Reino Unido: novas abordagens para divisÔes de classe contemporùneas

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    O objetivo do artigo Ă© demonstrar as “novas” elites que emergem no Reino Unido no contexto econĂŽmico, polĂ­tico e social do neoliberalismo. Para tal, utilizam-se os amplos trabalhos de Mike Savage acerca do significado do estudo de elites para as formas contemporĂąneas das divisĂ”es sociais. Os dados do Great British Class Survey servem de base para este autor delinear os elementossociolĂłgicos centrais da composição destas elites da financeirização. Descrevem-se as clivagens em termos de mobilidade social, educação, localização e politização geradas pela concentração de distintos tipos de capital (econĂŽmico, social e cultural). A partir da especificidade britĂąnica, pretende-se contribuir para o desenvolvimento da sociologia das elites tanto na discussĂŁo de novas perspectivas quanto nos limites e possibilidades da abordagem em diferentes contextos geogrĂĄficos, polĂ­ticos e sociaisO objetivo do artigo Ă© demonstrar as “novas” elites que emergem no Reino Unido no contexto econĂŽmico, polĂ­tico e social do neoliberalismo. Para tal, utilizam-se os amplos trabalhos de Mike Savage acerca do significado do estudo de elites para as formas contemporĂąneas das divisĂ”es sociais. Os dados do Great British Class Survey servem de base para este autor delinear os elementos sociolĂłgicos centrais da composição destas elites da financeirização. Descrevem-se as clivagens em termos de mobilidade social, educação, localização e politização geradas pela concentração de distintos tipos de capital (econĂŽmico, social e cultural). A partir da especificidade britĂąnica, pretende-se contribuir para o desenvolvimento da sociologia das elites tanto na discussĂŁo de novas perspectivas quanto nos limites e possibilidades da abordagem em diferentes contextos geogrĂĄficos, polĂ­ticos e sociai

    Elites in the UK: new approaches to contemporary class divisions

    No full text
    Abstract The aim of this article is to demonstrate the “new” elites emerging in the UK amidst the economic, political and social context of neoliberalism. To do this, we examine the works of Mike Savage regarding what elite studies have meant for contemporary forms of social division. Using data from the Great British Class Survey, the author underlines sociological elements that are central to the composition of this financialised elite. We describe cleavages in terms of social mobility, education, location and politicization that are generated through the concentration of distinct types of capital (economic, social and cultural). Departing from the specific context of Great Britain, we intend to contribute to the development of a sociology of elites, through a discussion of both new perspectives and the limits and possibilities of treating different geographic, political and social contexts

    Elites no Reino Unido: novas abordagens para divisÔes de classe contemporùneas

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    Effect of natalizumab on disease progression in secondary progressive multiple sclerosis (ASCEND): a phase 3, randomised, double-blind, placebo-controlled trial with an open-label extension

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    Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic : an international, multicenter, comparative cohort study

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    PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

    Open data from the first and second observing runs of Advanced LIGO and Advanced Virgo

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    Advanced LIGO and Advanced Virgo are monitoring the sky and collecting gravitational-wave strain data with sufficient sensitivity to detect signals routinely. In this paper we describe the data recorded by these instruments during their first and second observing runs. The main data products are gravitational-wave strain time series sampled at 16384 Hz. The datasets that include this strain measurement can be freely accessed through the Gravitational Wave Open Science Center at http://gw-openscience.org, together with data-quality information essential for the analysis of LIGO and Virgo data, documentation, tutorials, and supporting software

    Search for intermediate-mass black hole binaries in the third observing run of Advanced LIGO and Advanced Virgo

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    International audienceIntermediate-mass black holes (IMBHs) span the approximate mass range 100−105 M⊙, between black holes (BHs) that formed by stellar collapse and the supermassive BHs at the centers of galaxies. Mergers of IMBH binaries are the most energetic gravitational-wave sources accessible by the terrestrial detector network. Searches of the first two observing runs of Advanced LIGO and Advanced Virgo did not yield any significant IMBH binary signals. In the third observing run (O3), the increased network sensitivity enabled the detection of GW190521, a signal consistent with a binary merger of mass ∌150 M⊙ providing direct evidence of IMBH formation. Here, we report on a dedicated search of O3 data for further IMBH binary mergers, combining both modeled (matched filter) and model-independent search methods. We find some marginal candidates, but none are sufficiently significant to indicate detection of further IMBH mergers. We quantify the sensitivity of the individual search methods and of the combined search using a suite of IMBH binary signals obtained via numerical relativity, including the effects of spins misaligned with the binary orbital axis, and present the resulting upper limits on astrophysical merger rates. Our most stringent limit is for equal mass and aligned spin BH binary of total mass 200 M⊙ and effective aligned spin 0.8 at 0.056 Gpc−3 yr−1 (90% confidence), a factor of 3.5 more constraining than previous LIGO-Virgo limits. We also update the estimated rate of mergers similar to GW190521 to 0.08 Gpc−3 yr−1.Key words: gravitational waves / stars: black holes / black hole physicsCorresponding author: W. Del Pozzo, e-mail: [email protected]† Deceased, August 2020

    The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study

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    AimThe SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery.MethodsThis was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin.ResultsOverall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P ConclusionOne in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease
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