109 research outputs found

    Study of dijet events with large rapidity separation in proton-proton collisions at s \sqrt{s} = 2.76 TeV

    Get PDF
    The cross sections for inclusive and Mueller-Navelet dijet production are measured as a function of the rapidity separation between the jets in proton-proton collisions at s√ = 2.76 TeV for jets with transverse momentum pT > 35 GeV and rapidity |y| 20 GeV is introduced to improve the sensitivity to the effects of the Balitsky-Fadin-Kuraev-Lipatov (BFKL) evolution. The measurement is compared with the predictions of various Monte Carlo models based on leading-order and next-to-leading-order calculations including the Dokshitzer-Gribov-Lipatov-Altarelli-Parisi leading-logarithm (LL) parton shower as well as the LL BFKL resummation

    Tracker Operation and Performance at the Magnet Test and Cosmic Challenge

    Get PDF
    During summer 2006 a fraction of the CMS silicon strip tracker was operated in a comprehensive slice test called the Magnet Test and Cosmic Challenge (MTCC). At the MTCC, cosmic rays detected in the muon chambers were used to trigger the readout of all CMS sub-detectors in the general data acquisition system and in the presence of the 4 T magnetic field produced by the CMS superconducting solenoid. This document describes the operation of the Tracker hardware and software prior, during and after data taking. The performance of the detector as resulting from the MTCC data analysis is also presented

    Observation of a New Excited Beauty Strange Baryon Decaying to Ξb- π+π-

    Get PDF
    The Ξb-π+π- invariant mass spectrum is investigated with an event sample of proton-proton collisions at s=13 TeV, collected by the CMS experiment at the LHC in 2016-2018 and corresponding to an integrated luminosity of 140 fb-1. The ground state Ξb- is reconstructed via its decays to J/ψΞ- and J/ψΛK-. A narrow resonance, labeled Ξb(6100)-, is observed at a Ξb-π+π- invariant mass of 6100.3±0.2(stat)±0.1(syst)±0.6(Ξb-) MeV, where the last uncertainty reflects the precision of the Ξb- baryon mass. The upper limit on the Ξb(6100)- natural width is determined to be 1.9 MeV at 95% confidence level. The low Ξb(6100)- signal yield observed in data does not allow a measurement of the quantum numbers of the new state. However, following analogies with the established excited Ξc baryon states, the new Ξb(6100)- resonance and its decay sequence are consistent with the orbitally excited Ξb- baryon, with spin and parity quantum numbers JP=3/2-

    Severe early onset preeclampsia: short and long term clinical, psychosocial and biochemical aspects

    Get PDF
    Preeclampsia is a pregnancy specific disorder commonly defined as de novo hypertension and proteinuria after 20 weeks gestational age. It occurs in approximately 3-5% of pregnancies and it is still a major cause of both foetal and maternal morbidity and mortality worldwide1. As extensive research has not yet elucidated the aetiology of preeclampsia, there are no rational preventive or therapeutic interventions available. The only rational treatment is delivery, which benefits the mother but is not in the interest of the foetus, if remote from term. Early onset preeclampsia (<32 weeks’ gestational age) occurs in less than 1% of pregnancies. It is, however often associated with maternal morbidity as the risk of progression to severe maternal disease is inversely related with gestational age at onset2. Resulting prematurity is therefore the main cause of neonatal mortality and morbidity in patients with severe preeclampsia3. Although the discussion is ongoing, perinatal survival is suggested to be increased in patients with preterm preeclampsia by expectant, non-interventional management. This temporising treatment option to lengthen pregnancy includes the use of antihypertensive medication to control hypertension, magnesium sulphate to prevent eclampsia and corticosteroids to enhance foetal lung maturity4. With optimal maternal haemodynamic status and reassuring foetal condition this results on average in an extension of 2 weeks. Prolongation of these pregnancies is a great challenge for clinicians to balance between potential maternal risks on one the eve hand and possible foetal benefits on the other. Clinical controversies regarding prolongation of preterm preeclamptic pregnancies still exist – also taking into account that preeclampsia is the leading cause of maternal mortality in the Netherlands5 - a debate which is even more pronounced in very preterm pregnancies with questionable foetal viability6-9. Do maternal risks of prolongation of these very early pregnancies outweigh the chances of neonatal survival? Counselling of women with very early onset preeclampsia not only comprises of knowledge of the outcome of those particular pregnancies, but also knowledge of outcomes of future pregnancies of these women is of major clinical importance. This thesis opens with a review of the literature on identifiable risk factors of preeclampsia

    Precision mouse models with expanded tropism for human pathogens

    Get PDF
    A major limitation of current humanized mouse models is that they primarily enable the analysis of human-specific pathogens that infect hematopoietic cells. However, most human pathogens target other cell types, including epithelial, endothelial and mesenchymal cells. Here, we show that implantation of human lung tissue, which contains up to 40 cell types, including nonhematopoietic cells, into immunodeficient mice (lung-only mice) resulted in the development of a highly vascularized lung implant. We demonstrate that emerging and clinically relevant human pathogens such as Middle East respiratory syndrome coronavirus, Zika virus, respiratory syncytial virus and cytomegalovirus replicate in vivo in these lung implants. When incorporated into bone marrow/liver/thymus humanized mice, lung implants are repopulated with autologous human hematopoietic cells. We show robust antigen-specific humoral and T-cell responses following cytomegalovirus infection that control virus replication. Lung-only mice and bone marrow/liver/thymus-lung humanized mice substantially increase the number of human pathogens that can be studied in vivo, facilitating the in vivo testing of therapeutics

    Scientific abstracting,

    No full text

    The usefulness of analytic abstracts,

    No full text

    The Physical review.

    No full text
    Vols. for 1903- include Proceedings of the American Physical Society."A journal of experimental and theoretical physics.""Conducted with the co-operation of the American physical society," 1903-12; "conducted by the American physical society," 1913- In feb. 1903 the separate publication of the Bulletin of the society was discontinued and its Proceedings published in the Physical review.Published for Cornell university, July 1893-Jan. 1903.Editors: July 1893-Oct. 1895, E.L. Nichols, E.G. Merritt.--Nov. 1895-Dec. 1912, E.L. Nichols, E.G. Merritt, Frederick Bedell.--Jan. 1913-Dec. 1922, Frederick Bedell and others.--Jan. 1923- G.S. Fulcher and others.Bimonthly, July 1893-June 1897; "at least 5 numbers" each half year, July 1897-June 1902; monthly, June 1902-Vols. 133-140 issued in two sections: A and B.Vols. for 1903- include Proceedings of the American Physical Society.Mode of access: Internet.Publ. by the American Institute of Physics under the ed. supervision of American Physical Society, Aug. 1, 1932- ; conducted with the cooperation of American Physical Society, 1903-July 15, 1932.Publ. for Cornell University, July 1893-Jan. 1903.Subject index: Vols. 17-80, 1921-50. 1 v.Author indexes: Vols. 101-120, 1956-60 (includes index to Physical review letters) 1 v.; Vols. 121-140, 1961-65 (includes index to Physical review letters) 1 v.; Vols. 141-188, 1966-69 (includes index to Physical review letters) 1 v.General index: Vol. 1-ser. 2, v. 16, 1893-1920. 1 v.Split into: Physical review. A, General physics, ISSN 0556-2791; Physical Review. B, Solid state physics, ISSN 0556-2805; Physical review. C, Nuclear physics, ISSN 0556-2813; Physical review. D, Particles and fields, ISSN 0556-2821.From 1958 Letters to the editor section publ. separately as: Physical review letters, ISSN 0031-9007
    corecore