ジョウソウ タイキ ソセイ ノ チョクセツ ソクテイ ヨウシツ リョウ ブンセキキ ノ ケンキュウ

京都大学0048新制・論文博士工学博士乙第1729号論工博第397号新制||工||179(附属図書館)UT51-46-B114(主査)教授 前田 憲一, 教授 小川 徹, 教授 加藤 進学位規則第5条第2項該当Kyoto UniversityDFA

Prospective Study of Zinc Intake and Risk of Type 2 Diabetes in Women

OBJECTIVE: The aim of this study is to investigate the intake of zinc in relation to risk of type 2 diabetes in U.S. women. RESEARCH DESIGN AND METHODS: Dietary intakes of zinc and other nutrients were assessed and updated using a validated food frequency questionnaire from 1980 to 2002 among 82,297 women who were aged 33–60 years at baseline in 1980 and followed up to 2004 in the Nurses' Health Study. RESULTS: During the 24 years of follow-up, 6,030 incident cases of type 2 diabetes were ascertained. After adjustment of lifestyle and dietary risk factors, the relative risks (RRs) (95% CI) of type 2 diabetes comparing the highest with the lowest quintiles were 0.90 (0.82–0.99) (Ptrend = 0.04) for total zinc intake and 0.92 (0.84–1.00) (Ptrend = 0.009) for dietary zinc intake from food sources, respectively. We further found an inverse association for dietary zinc to heme iron ratio. After multivariate adjustment of covariates, the RRs (95% CI) across quintiles of this ratio were 1.0 (reference), 0.93 (0.86–1.01), 0.86 (0.79–0.94), 0.82 (0.75–0.90), and 0.72 (0.66–0.80), respectively (Ptrend < 0.0001). CONCLUSIONS: Higher zinc intake may be associated with a slightly lower risk of type 2 diabetes in women. More studies are warranted to confirm this association and to explore potential mechanisms

Ion Composition Measurement with a Rocket-Borne Mass Spectrometer at Syowa Station

A positive ion mass spectrometer was flown on the S-210JA-12 rocket at Syowa Station in the Antarctic Region (69°00'S, 39°35'E), at 13:00 LT, on Feb. 11, 1972. Measurements were obtained from about 108 km, its apogee, to about 80km on descent. A few metal ions in E-region and hydracted ions in D-region of the ionosphere were observed in addition to the main NO^+ and O^+_2 profiles