8 research outputs found

    Effect of indirect composite treatment microtensile bond strength of self-adhesive resin cements

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    Background: No specific indications about the pre-treatment of indirect composite restorations is provided by the manufacturers of most self-adhesive resin cements. The potential effect of silane treatment to the bond strength of the complete tooth/indirect restoration complex is not available.The aim of this study was to determine the contribution of different surface treatments on microtensile bond strength of composite overlays to dentin using several self-adhesive resin cements and a total-etch one. Material and Methods: Composite overlays were fabricated and bonding surfaces were airborne-particle abraded and randomly assigned to two different surface treatments: no treatment or silane application (RelyX Ceramic Primer) followed by an adhesive (Adper Scotchbond 1 XT). Composite overlays were luted to flat dentin surfaces using the following self-adhesive resin cements: RelyX Unicem, G-Cem, Speedcem, Maxcem Elite or Smartcem2, and the total-etch resin cement RelyX ARC. After 24 h, bonded specimens were cut into sticks 1 mm thick and stressed in tension until failure. Two-way ANOVA and SNK tests were applied at α=0.05. Results: Bond strength values were significantly influenced by the resin cement used ( p <0.001). However, composite surface treatment and the interaction between the resin cement applied and surface treatment did not significantly affect dentin bond strength ( p >0.05). All self-adhesive resin cements showed lower bond strength values than the total-etch RelyX ARC. Among self-adhesive resin cements, RelyX Unicem and G-Cem attained statistically higher bond strength values. Smartcem2 and Maxcem Elite exhibited 80-90% of pre-test failures. Conclusions: The silane and adhesive application after indirect resin composite sandblasting did not improve the bond strength of dentin-composite overlay complex. Selection of the resin cement seems to be a more relevant factor when bonding indirect composites to dentin than its surface treatmen

    Curing effectiveness of resin composites at different exposure times using LED and halogen units

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    Objective: To compare the polymerization effectiveness of two resin composites cured with a quartz tungsten halogen (QTH) lamp or a light emitting diodes (LED) unit. Study design: Filtek Z250 (3M ESPE) and Spectrum TPH (Dentsply DeTrey) resin composites were placed in 9 mm deep and 4 mm wide metallic molds and cured using the QTH light Hilux 200 (Benlioglu) or the LED unit Smartlite IQ (Dentsply DeTrey) for 20 or 40 s (three specimens per group). Measurement of depth of cure was carried out by means of a scraping technique, according to ISO 4049. The microhardness measurements were performed using a calibrated Vickers indenter (100 g load, 30 s) at depths of 0.5, 1.5, 2.5, 3.5, 4.5 and 5.5 mm from the top of the composite in the same specimens. Results were analyzed by ANOVA, Student ́s t and Student-Newman-Keuls tests (p<0.05). Results: Filtek Z250 exhibited higher depth of cure and Vickers microhardness values than Spectrum TPH under each experimental condition evaluated. Depth of cure and microhardness were not affected by the curing light used. However, hardness values were influenced by the interaction between curing light and exposure time. Specimens irradiated for 20 s exhibited higher microhardness values when the LED curing light was used. Exposure time had no influence on the microhardness values for depths from 0.5 to 2.5 mm. At higher depths, irradiation for 40 s produced greater microhardness values. Conclusions: Curing effectiveness of resin composite is not only dependent on the curing light unit. Results vary greatly with composite brand, thickness of the resin composite and the duration of the exposure

    Cryopreservation Effect on Proliferative and Chondrogenic Potential of Human Chondrocytes Isolated from Superficial and Deep Cartilage

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    [Abstract] Objectives: To compare the proliferative and chondrogenic potential of fresh and frozen chondrocytes isolated from superficial and deep articular cartilage biopsies. Materials and Methodology: The study included 12 samples of fresh and frozen healthy human knee articular cartilage. Cell proliferation was tested at 3, 6 and 9 days. Studies of mRNA quantification, protein expression and immunofluorescence for proliferation and chondrogenic markers were performed. Results: Stimulation of fresh and frozen chondrocytes from both superficial and deep cartilage with fetal bovine serum produced an increase in the proliferative capacity compared to the non-stimulated control group. In the stimulated fresh cells group, the proliferative capacity of cells from the deep biopsy was greater than that from cells from the superficial biopsy (0.046 vs 0.028, respectively, p<0.05). There was also a significant difference between the proliferative capacity of superficial zone fresh (0.028) and frozen (0.051) chondrocytes (p<0.05). CCND1 mRNA and protein expression levels, and immunopositivity for Ki67 revealed a higher proliferative capacity for fresh articular chondrocytes from deep cartilage. Regarding the chondrogenic potential, stimulated fresh cells showed higher SOX9 and Col II expression in chondrocytes from deep than from superficial zone (p<0.05, T student test). Conclusions: The highest rate of cell proliferation and chondrogenic potential of fresh chondrocytes was found in cells obtained from deep cartilage biopsies, whereas there were no statistically significant differences in proliferative and chondrogenic capacity between biopsy origins with frozen chondrocytes. These results indicate that both origin and cryopreservation affect the proliferative and chondrogenic potential of chondrocytes.Servizo Galego de SaĂșde; PS07/84Instituto de Salud Carlos III; CIBER BBN CB06-01-0040Ministerio Ciencia e Innovacion; PLE2009-0144Ministerio Ciencia e InnovaciĂłn; PI 08/202

    RICORS2040 : The need for collaborative research in chronic kidney disease

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    Chronic kidney disease (CKD) is a silent and poorly known killer. The current concept of CKD is relatively young and uptake by the public, physicians and health authorities is not widespread. Physicians still confuse CKD with chronic kidney insufficiency or failure. For the wider public and health authorities, CKD evokes kidney replacement therapy (KRT). In Spain, the prevalence of KRT is 0.13%. Thus health authorities may consider CKD a non-issue: very few persons eventually need KRT and, for those in whom kidneys fail, the problem is 'solved' by dialysis or kidney transplantation. However, KRT is the tip of the iceberg in the burden of CKD. The main burden of CKD is accelerated ageing and premature death. The cut-off points for kidney function and kidney damage indexes that define CKD also mark an increased risk for all-cause premature death. CKD is the most prevalent risk factor for lethal coronavirus disease 2019 (COVID-19) and the factor that most increases the risk of death in COVID-19, after old age. Men and women undergoing KRT still have an annual mortality that is 10- to 100-fold higher than similar-age peers, and life expectancy is shortened by ~40 years for young persons on dialysis and by 15 years for young persons with a functioning kidney graft. CKD is expected to become the fifth greatest global cause of death by 2040 and the second greatest cause of death in Spain before the end of the century, a time when one in four Spaniards will have CKD. However, by 2022, CKD will become the only top-15 global predicted cause of death that is not supported by a dedicated well-funded Centres for Biomedical Research (CIBER) network structure in Spain. Realizing the underestimation of the CKD burden of disease by health authorities, the Decade of the Kidney initiative for 2020-2030 was launched by the American Association of Kidney Patients and the European Kidney Health Alliance. Leading Spanish kidney researchers grouped in the kidney collaborative research network Red de Investigación Renal have now applied for the Redes de Investigación Cooperativa Orientadas a Resultados en Salud (RICORS) call for collaborative research in Spain with the support of the Spanish Society of Nephrology, Federación Nacional de Asociaciones para la Lucha Contra las Enfermedades del Riñón and ONT: RICORS2040 aims to prevent the dire predictions for the global 2040 burden of CKD from becoming true

    Characterisation of microbial attack on archaeological bone

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    As part of an EU funded project to investigate the factors influencing bone preservation in the archaeological record, more than 250 bones from 41 archaeological sites in five countries spanning four climatic regions were studied for diagenetic alteration. Sites were selected to cover a range of environmental conditions and archaeological contexts. Microscopic and physical (mercury intrusion porosimetry) analyses of these bones revealed that the majority (68%) had suffered microbial attack. Furthermore, significant differences were found between animal and human bone in both the state of preservation and the type of microbial attack present. These differences in preservation might result from differences in early taphonomy of the bones. © 2003 Elsevier Science Ltd. All rights reserved

    Suelo y planta. Índices. Volumen 2

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    Effects of the landspreading of pig slurry on the yield and composition of capsi cum annuum. M. P. Bernal, A. Roig, J. Cegarra and R. Madrid.-- CaracterĂ­sticas micromorfolĂłgicas de suelos de humedales en zonas semiĂĄridas (Cuenca del Duero). J. Benayas, M. a T. de la Cruz y J. M. a Rey. Benayas.-- AplicaciĂłn de la tĂ©cnica de porosimetrĂ­a por intrusiĂłn de mercurio en el estudio de la porosidad de un conjunto de suelos del NW de España. E. Benito, A. Paz y R. Pini.-- Cambios fĂ­sicos y quĂ­micos durante la maduraciĂłn de Vitis vinĂ­fera, variedad Monastrell, en la D. O. Jumilla. G. Navarro, F. Pardo, P. JimĂ©nez, J. Oliva y S. Navarro.-- Micorrizas vesĂ­culo - arbusculares en parcelas que se encuentran en sucesiĂłn- regeneraciĂłn en Jos Andes tropicales. M. Montilla, R. A. Herrera y M. Monasterio.-- Efectos de los incendios forestales sobre el suelo. J. GonzĂĄlez, M. C. FernĂĄndez y G.P. Gimeno.-- MineralogĂ­a de suelos formados sobre calizas en Galicia. M. T. Taboada, M. B. Silva y M. c. Villar.-- Efecto de tratamientos foliares con Ti (IV) sobre nutriciĂłn, producciĂłn y calidad de fruto en plantas de Capsicum annuum, L. F. MartĂ­nez-SĂĄnchez, J. L. GimĂ©nez, M. Carvajal, A. Moreno, J. L. Fuentes y C. F. Alcaraz.-- Poder discriminante de las clasificaciones: aplicaciĂłn a los suelos de la depresiĂłn Guadix- Baza (Granada). A. Iriarte, E. Barahona y C. Gil de Carrasco.-- Aspects of elm propagation by soft and hardwood cuttings. L. Mittempergher, G. Bartolini, F. Ferrini and M. Panicucci.-- Metales pesados en las escombreras de la mina Puentes (La Coruña): influencia de las condiciones Eh- pH. F. MacĂ­ass, M. T. Barral, C. Monterroso y R. M. Calvo.-- Incidencia del fĂłsforo en la mineralizaciĂłn del nitrĂłgeno orgĂĄnico de un lodo de depuradora en dos suelos calizos. ExtracciĂłn mediante EUF. l. VerdĂș, l. GĂłmez, F. BurlĂł y J, Mataix.-- DinĂĄmica del proceso de sorciĂłn de fĂłsforo en suelos. DefiniciĂłn de indicadores. T. Crisanto y P. P. Iturbe.-- Estudio de la adsorciĂłn de atrazina por polimeros modelos y por un ĂĄcido homico mediante la tĂ©cnica de diĂĄlisis. M. Schiavon, J. M. Portal, F. Andreux y G. Bertin.-- Oxidos de hierro sintĂ©ticos y agregaciĂłn en muestras de caolinita y cuarzo. M. Arias, M. T. Barraly F. DĂ­az-Fierros.-- Fertilization with NPK and humate NPK: Plant yield and nutrient dynamics. A. Benedetti, A. Figliolia, C. Izza, R. lndiati and S. Canali.-- AplicaciĂłn de un mĂ©todo de fraccionamiento de especies alumĂ­nicas a soluciones de suelos de Galicia. E. Alvarez y R. Calvo.-- Contenido y evoluciĂłn de 9 elementos quĂ­micos en pimiento piquillo a lo largo de su desarrollo. R. Y. Cavero, A. EcheverrĂ­a, F. Iribarren y M. L. LĂłpez.-- DistribuciĂłn del tamaño de poros, porosidad total y su variabilidad con la dedicaciĂłn en el horizonte orgĂĄnico de un cambisol gleico. A. Paz y E. Benito.-- CaracterizaciĂłn de la textura superficial de granos de cuarzo en suelos con horizontes texturalmente contrastados. M. T. MartĂ­n Patino, R. J. Ballesta, V. Cala y A. Alvarez .-- UtilizaciĂłn de un lodo aerobio como sustitutivo de fertilizantes fosforados inorgĂĄnicos. M. Ayuso, T. HernĂĄndez, C. GarcĂ­a y F. Costa.-- Movilidad de aldicarb y de carbofurano en columnas de suelo. A. Apaolaza, F. J. Arranz y E. Revilla.-- DegradaciĂłn de clorofila en cloroplastos incubados en medio isotĂłnico con la fracciĂłn celular extracloroplĂĄstica. J. Cuello, A. Lahora y B. Stibater.-- EspeciaciĂłn quĂ­mica de zinc y cadmio en suelos de cultivo. V. Cala, A. M. Alvarez, R. Vigil de la Villa y M. Gasea.-- Germination with alternate temperatures of weeds infesting irrigated vegetables. R. GonzĂĄlez Ponce, A. Herce and M. L. Salas.-- EvaluaciĂłn de la fertilidad de los vertisoles de la provincia de Badajoz (España) mediante cultivos experimentales. ProducciĂłn en materia seca y nutrientes del cultivo. A. GarcĂ­a y A. LĂłpez.-- Isozymes peroxidase in cytokinin treated seedlings of Corylus avellana L. C. Colinas, C. DĂ­az-Sala and R. RodrĂ­guez.-- Respuestas de las plantas a la contaminaciĂłn por metales pesados. J. BarcelĂł y Ch. Poschenrieder.-- N, P and K balance in winter wheat in the pampean semiarid region of Argentina. R. A. Rosell, M. R. Landriscini and J. A. Galantini.-- UtilizaciĂłn de residuos urbanos como fertilizantes orgĂĄnicos. T. HernĂĄndez, C. GarcĂ­a, F. Costa, J. A. Valero y M. Ayuso.-- InducciĂłn de organogĂ©nesis en cotiledones de Pinus canariensis. C. MartĂ­nez Pulido.-- HidrĂłxidos de aluminio sintĂ©ticos y agregaciĂłn en muestras de caolinita y cuarzo . . M. Arias, M. T. Barral y F. DĂ­az-Fierros.-- ProducciĂłn de endoglucanasas por Glomus mosseae y su posible implicaciĂłn en la colonizaciĂłn de raf<::es de cebolla. J. M. GarcĂ­a-Garrido, l. GarcĂ­a-Romera y J. A. Ocampo.-- Estudio comparado de la fracciĂłn mineral del suelo de cultivo· y de las heces' de Allolobophora molleri (Lumbricidae) Rosa, 1889.D. Trigo y D. J. DĂ­az CosĂ­n.-- DeterminaciĂłn de la homogeneidad mĂșltiple utilizando diferentes niveles de taxones en perfiles de suelos de la cuenca media y alta del rĂ­o MotatĂĄn. Estados MĂ©rida y Trujillo. Venezuela. J. Jaimes, J. Oballos y G. Ochoa.-- AdsorciĂłn - desorciĂłn de picloram por arcillas y Ăłxidos. E. A. Ferreiro, S. G. de Bussetti.-- Influencia de la carga y el potencial hĂ­drico durante la compactaciĂłn sobre la resistencia a la tracciĂłn de unidades estructurales de suelo en estado seco. A. Paz y J. GuĂ©rif.-- Residuos orgĂĄnicos: Incidencia de su aplicaciĂłn sobre la composiciĂłn mineral del fruto del tomate, I. GĂłmez, J. Navarro-Pedreño y J. Mataix.-- Growth, cell wall elasticity and plasticity in Zea mays L. coleoptiles exposed to cadmium. B. GunsĂ©, M. Llugany, Ch. Poschenrieder and J. BarcelĂł.-- Effects of high zinc and cadmium concentrations on the metallophyte Thlaspi caerulescens J. et C. Presl. (Brassicaceae). J. MĂłdico, Ch. Poschenrieder, M. D. VĂĄzquez and J. BarcelĂł.--DeterminaciĂłn del grado ·de contaminaciĂłn de los rlos mediante el estudio conjunto de la composiciĂłn de sus aguas y sedimentos. A. Bustos, C. Ortega y I. Sastre.-- Influencia del grado de madurez de un residuo urbano sobre la germinaciĂłn y disponibilidad de nitrĂłgeno. M. Ayuso, T. HernĂĄndez, F. Costa, C. GarcĂ­a y J. A. Pascual.-- Influencia del nitrĂłgeno sobre el desarrollo in vitro del portainjerto de vid.--A. Villegas, C. Mozuelos, M. Cantos y A. Troncoso.-- Efecto del alpechĂ­n sobre la solubilizaciĂłn de metales pesados. M. Bejarano y L. Madrid.-- Aporte foliar de titanio a plantas de pimiento pimentonero. Influencia sobre el balance de nutriciĂłn en pericarpio de fruto. M. Carvajal, M. J. Frutos, J. L. GimĂ©nez, C. F. Alcaraz y F. MartĂ­nez-SĂĄnchez.-- Effects of phosphate, sulfate and molibdate on the uptake and distribution of technetium-99 in bush bean plants. A. BennĂĄssar, C. Cabot, J. BarcelĂł y Ch. Poschenrieder.-- Uptake, translocation and efficiency of nutrients in Phaseolus vulgaris L. cv. contender exposed to aluminum. N. Massot, Ch. Poschenrieder and J. BarcelĂł.-- Efecto del cadmio sobre Ü1. absorciĂłn y distribuciĂłn de manganeso en distintas variedades de Lactuca. A. GĂĄrate, I. Ramos y J. J. Lucena.-- Efecto residual de diferentes residuos orgĂĄnicos sobre un cultivo de cebada. F. Costa, T. HernĂĄndez, C. GarcĂ­a, M. Ayuso, J. A. Pascual y A. Polo.-- Beneficial effects of low chromium III concentrations in iron deficient maize plants. Ch. Poschenrieder, M. D. VĂĄzquez, A. Bonet and J. BarcelĂł.-- DepresiĂłn en el rendimiento del maĂ­z causado por altas concentraciones de N residual en el suelo. C. Pozo, C. Cruces, J. M. Ramos, y L. F. GarcĂ­a del Moral.-- SelecciĂłn y caracterizaciĂłn de una lĂ­nea celular de limonero tolerante a estrĂ©s salino. A. Piquera y E. HellĂ­n.-- Efectos del As en el comportamiento vegetal de Lycopersicum esculentum Mili. RelaciĂłn del As en hojas y frutos con parĂĄmetros fĂ­sicos. F. BurlĂł, A. Carbonell y J. Mataix.--Niveles crĂ­ticos y equilibrios Ăłptimos de macronutrientes en la fertilizaciĂłn diferenciada de la vid. R. Sarmiento, J. L. GarcĂ­a, M. C. Grande, M. C. Vil/alĂłn, A. de Castro y C. Mozuelos.-- Niveles crĂ­ticos y equilibrios Ăłptimos de micronutrientes en la fertilizaciĂłn diferenciada de la vid. R. Sarmiento, J. L. GarcĂ­a, M. C. Grande, M. C. Vil/alĂłn, A. de Castro y C. Mozuelos.-- Efecto de un compost de lodo residual sobre el rendimiento y contenido de Cd y Ni en diversos cultivos. I. Walter, R. Miralles y M. Bigeriego.-- Estudio del eflujo neto de H+ por raĂ­ces aeropĂłnicas estĂ©riles de plantulas de girasol (Helianthus annuus L.) bajo condiciones de toxicidad de B. F. Espinosa y M. C. Alvarez-Tinaut-- Efecodel riego con aguas residuales urbanas depuradas sobre la disponibilidad de metales pesados para la planta. A. InglĂ©s, M. GĂłmez y R. Nogales.-- Diferential response of four maize (Zea mays L.) varieties to aluminum toxicity. P. Guevara, Ch. Poschenrieder and BarcelĂł.-- ComparaciĂłn de los efectos de molibdeno y vanadio en Phaseo/us vulgaris L.: Crecimiento, proteĂ­nas y actividades enzimĂĄticas de la nitrato-reducciĂłn. D. Saco, M. Alvarez y S. MartĂ­n.-- Influencia de la fertirrigaciĂłn N, P, K sobre diversos nutrientes totales y solubles. Su evoluciĂłn temporal. J. L. Va/enzuela, A. del RĂ­o, A. SĂĄnchez, l. LĂłpez-Cantarero y L. Romero.-- ValoraciĂłn de mĂ©todos de extracciĂłn de mercurio en suelos contaminados. J. J. Lucena, L. E. HernĂĄndez, S. Olmos y R. Carpena Ruiz.-- Relaciones entre contenidos totales de Zn, Pb, Cu y Cd en suelos y plantas. A. M. Moreno, L. PĂ©rez y J. GonzĂĄlez.-- Effect of N-nutrition and irrigation water on Carob-Tree (Ceratonia si/iqua L.). Growth responses. P. Correia y M. A. Martins-LouçaoPeer reviewe

    4Th Pediatric Allergy And Asthma Meeting (Paam)

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    WORKSHOP 4: Challenging clinical scenarios (CS01–CS06), CS01 Bullous lesions in two children: solitary mastocytoma, S. Tolga Yavuz, Ozan Koc, Ali Gungor, Faysal Gok, CS02 Multi-System Allergy (MSA) of cystic fibrosis: our institutional experience, Jessica Hawley, Christopher O’Brien, Matthew Thomas, Malcolm Brodlie, Louise Michaelis, CS03 Cold urticaria in pediatric age: an invisible cause for severe reactions, InĂȘs Mota, Ângela Gaspar, Susana Piedade, Graça Sampaio, JosĂ© Geraldo Dias, Miguel Paiva, MĂĄrio Morais-Almeida, CS04 Angioedema with C1 inhibitor deficiency in a girl: a challenge diagnosis, Cristina Madureira, TĂąnia Lopes, Susana Lopes, Filipa Almeida, Alexandra Sequeira, Fernanda Carvalho, JosĂ© Oliveira, CS05 A child with unusual multiple organ allergy disease: what is the primer?, Fabienne Gay-Crosier, CS06 A case of uncontrolled asthma in a 6-year-old patient, Ioana-Valentina Nenciu, Andreia Florina Nita, Alexandru Ulmeanu, Dumitru Oraseanu, Carmen Zapucioiu, ORAL ABSTRACT SESSION 1: Food allergy (OP01–OP06), OP01 Food protein-induced enterocolitis syndrome: oral food challenge outcomes for tolerance evaluation in a Pediatric Hospital, Adrianna Machinena, Olga DomĂ­nguez SĂĄnchez, Montserrat Alvaro Lozano, Rosa Jimenez Feijoo, Jaime Lozano Blasco, MĂČnica Piquer Gibert, MÂȘ Teresa Giner Muñoz, Marcia Dias da Costa, Ana Maria Plaza MartĂ­n, OP02 Characteristics of infants with food protein-induced enterocolitis syndrome and allergic proctocolitis, Ebru Arik Yilmaz, Özlem Cavkaytar, Betul Buyuktiryaki, Ozge Soyer, Cansin Sackesen, OP03 The clinical and immunological outcomes after consumption of baked egg by 1–5 year old egg allergic children: results of a randomised controlled trial, MerrynNetting, Adaweyah El-Merhibi, Michael Gold, PatrickQuinn, IrmeliPenttila, Maria Makrides, OP04 Oral immunotherapy for treatment of egg allergy using low allergenic, hydrolysed egg, Stavroula Giavi, Antonella Muraro, Roger Lauener, Annick Mercenier, Eugen Bersuch, Isabella M. Montagner, Maria Passioti, NicolĂČ Celegato, Selina Summermatter, Sophie Nutten, Tristan Bourdeau, Yvonne M. Vissers, Nikolaos G. Papadopoulos, OP05 Chemical modification of a peanut extract results in an increased safety profile while maintaining efficacy, Hanneke van der Kleij, Hans Warmenhoven, Ronald van Ree, Raymond Pieters, Dirk Jan Opstelten, Hans van Schijndel, Joost Smit, OP06 Administration of the yellow fever vaccine in egg allergic children, Roisin Fitzsimons, Victoria Timms, George Du Toit, ORAL ABSTRACT SESSION 2: Asthma (OP07–OP12), OP07 Previous exacerbation is the most important risk factor for future exacerbations in school-age children with asthma, S. Tolga Yavuz, Guven Kaya, Mustafa Gulec, Mehmet Saldir, Osman Sener, Faysal Gok, OP08 Comparative study of degree of severity and laboratory changes between asthmatic children using different acupuncture modalities, Nagwa Hassan, Hala Shaaban, Hazem El-Hariri, Ahmed Kamel Inas E. Mahfouz, OP09 The concentration of exhaled carbon monoxide in asthmatic children with different controlled stadium, Papp Gabor, Biro Gabor, Kovacs Csaba, OP10 Effect of vitamin D3 supplementation during pregnancy on risk of persistent wheeze in the offspring: a randomised clinical trial, Bo Chawes, Klaus BĂžnnelykke, Jakob Stokholm, Lene Heickendorff, Susanne Brix, Morten Rasmussen, Hans Bisgaard, OP11 Lung function development in childhood, Henrik Wegener Hallas, Bo Chawes, Lambang Arianto, Hans Bisgaard, OP12 Is the effect of maternal and paternal asthma different in female and male children before puberty?, Maike Pincus, Thomas Keil, Andreas Reich, Ulrich Wahn, Susanne Lau, Linus Grabenhenrich, ORAL ABSTRACT SESSION 3: Epidemiology—genetics (OP13–OP18), OP13 Lifestyle is associated with incidence and category of allergen sensitisation: the ALADDIN birth cohort, Sara Fagerstedt, Helena Marell Hesla, Emelie Johansson, Helen Rosenlund, Axel Mie, Annika Scheynius, Johan Alm, OP15 Maternal filaggrin mutations increase the risk of atopic dermatitis in children: an effect independent of mutation inheritance, Jorge Esparza-Gordillo, Anja Matanovic, Ingo Marenholz, Anja Bauerfeind, Klaus Rohde, Katja Nemat, Min-Ae Lee-Kirsch, Magnus Nordenskjöld, Marten C. G. Winge, Thomas Keil, Renate KrĂŒger, Susanne Lau, Kirsten Beyer, Birgit Kalb, Bodo Niggemann, Norbert HĂŒbner, Heather J. Cordell, Maria Bradley, Young-Ae Lee, OP16 Allergic multimorbidity of asthma, rhinitis and eczema in the first 2 decades of the German MAS birth cohort, Thomas Keil, Hannah Gough, Linus Grabenhenrich, Dirk Schramm, Andreas Reich, John Beschorner, Antje Schuster, Carl-Peter Bauer, Johannes Forster, Fred Zepp, Young-Ae Lee, Renate Bergmann, Karl Bergmann, Ulrich Wahn, Susanne Lau, OP17 Childhood anaphylaxis: a growing concern, Filipe Benito Garcia, InĂȘs Mota, Susana Piedade, Ângela Gaspar, Natacha Santos, Helena PitĂ©, MĂĄrio Morais-Almeida, OP18 Indoor exposure to molds and dampness in infancy and its association to persistent atopic dermatitis in school age. Results from the Greek ISAAC II study, Athina Papadopoulou, Despina Mermiri, Elpida Xatziagorou, Ioannis Tsanakas, Stavroula Lampidi, Kostas Priftis, ORAL ABSTRACT SESSION 4: Pediatric rhinitis—immunotherapy (OP19–OP24), OP19 Associations between residential greenness and childhood allergic rhinitis and aeroallergen sensitisation in seven birth cohorts, Elaine Fuertes, Iana Markevych, Gayan Bowatte, Olena Gruzieva, Ulrike Gehring, Allan Becker, Dietrich Berdel, Michael Brauer, Chris Carlsten, Barbara Hoffmann, Anita Kozyrskyj, Caroline Lodge, Göran Pershagen, Alet Wijga, Heinrich Joachim, OP20 Full symptom control in pediatric patients with allergic rhinitis and asthma: results of a 2-year sublingual allergen immunotherapy study, Zorica Zivkovic, Ivana Djuric-Filipovic, Jasmina Jocić-Stevanovic, SneĆŸana Zivanovic, OP21 Nasal epithelium of different ages of atopic subjects present increased levels of oxidative stress and increased cell cytotoxicity upon rhinovirus infection, Styliani Taka, Dimitra Kokkinou, Aliki Papakonstantinou, Panagiota Stefanopoulou, Anastasia Georgountzou, Paraskevi Maggina, Sofia Stamataki, Vassiliki Papaevanggelou, Evangelos Andreakos, Nikolaos G. Papadopoulos, OP22 Cluster subcutaneous immunotherapy schedule: tolerability profile in children, Monica Piquer Gibert, Montserrat Alvaro Lozano, Jaime Lozano Blasco, Olga DomĂ­nguez SĂĄnchez, Rosa JimĂ©nez Feijoo, Marcia Dias da Costa, MÂȘ Teresa Giner Muñoz, Adriana Machinena Spera, Ana Maria Plaza MartĂ­n, OP23 Rhinitis as a risk factor for asthma severity in 11-year old children: population-based cohort study, Matea Deliu, Danielle Belgrave, Angela Simpson, Adnan Custovic, OP24 The Global Lung Function Initiative equations in airway obstruction evaluation of asthmatic children, JoĂŁo Gaspar Marques, Pedro Carreiro-Martins, Joana Belo, Sara Serranho, Isabel Peralta, Nuno Neuparth, Paula Leiria-Pinto, POSTER DISCUSSION SESSION 1: Food allergy (PD01–PD05), PD01 Allergen-specific humoral and cellular responses in children who fail egg oral immunotherapy due to allergic reactions, Marta Vazquez-Ortiz, Mariona Pascal, Ana Maria Plaza, Manel Juan, PD02 FoxP3 epigenetic features in children with cow milk allergy, Lorella Paparo, Rita Nocerino, Rosita Aitoro, Ilaria Langella, Antonio Amoroso, Alessia Amoroso, Carmen Di Scala, Roberto Berni Canani, PD04 Combined milk and egg allergy in early childhood: let them eat cake?, Santanu Maity, Giuseppina Rotiroti, Minal Gandhi, PD05 Introduction of complementary foods in relation to allergy and gut microbiota in farm and non-farm children, Karin Jonsson, Annika Ljung, Bill Hesselmar, Ingegerd Adlerbert, Hilde Brekke, Susanne Johansen, Agnes Wold, Ann-Sofie Sandberg, POSTER DISCUSSION SESSION 2: Asthma and wheeze (PD06–PD16), PD06 The association between asthma and exhaled nitric oxide is influenced by genetics and sensitisation, Björn Nordlund, Cecilia Lundholm, Villhelmina Ullemar, Marianne van Hage, Anne Örtqvist, Catarina Almqvist, PD09 Prevalence patterns of infant wheeze across Europe, Anna Selby, Kate Grimshaw, Thomas Keil, Linus Grabenhenrich, Michael Clausen, Ruta Dubakiene, Alessandro Fiocchi, Marek Kowalski, Nikos Papadopoulos, Marta Reche, Sigurveig Sigurdardottir, Aline Sprikkleman, Paraskevi Xepapadaki, Clare Mills, Kirsten Beyer, Graham Roberts, PD10 Epidemiologic changes in recurrent wheezing infants, Herberto Jose Chong Neto, Gustavo Falbo Wandalsen, Ana Carolina Dela Bianca, Carolina Aranda, Nelson Augusto RosĂĄrio, Dirceu SolĂ©, Javier Mallol, Luis GarcĂ­a Marcos, PD13 A single nucleotide polymorphism in the GLCCI1 gene is associated with response to asthma treatment in children, IvanaBanic, Matija Rijavec, Davor Plavec, Peter Korosec, Mirjana Turkalj, PD14 Pollen induced asthma: Could small molecules in pollen exacerbate the protein-mediated allergic response?, Alen Bozicevic, Maria De Mieri, Matthias Hamburger, PD15 A qualitative study to understand how we can empower teenagers to better self-manage their asthma, Simone Holley, Ruth Morris, Frances Mitchell, Rebecca Knibb, Susan Latter, Christina Liossi, Graham Roberts, PD16 Polymorphism of endothelial nitric oxide synthase (eNOS) gene among Egyptian children with bronchial asthma, Mostafa M. M. Hassan, POSTER DISCUSSION SESSION 3: Mechanisms—Epidemiology (PD17–PD21), PD17 Pregnancy outcomes in relation to development of allergy in a Swedish birth cohort, Malin Barman, Anna Sandin, Agnes Wold, Ann-Sofie Sandberg, PD18 Evolution of the IgE response to house dust mite molecules in childhood, Daniela Posa, Serena Perna, Carl-Peter Bauer, Ute Hoffmann, Johannes Forster, Fred Zepp, Antje Schuster, Ulrich Wahn, Thomas Keil, Susanne Lau, Kuan-Wei Chen, Yvonne Resch, Susanne Vrtala, Rudolf Valenta, Paolo Maria Matricardi, PD19 Antibody recognition of nsLTP-molecules as antigens but not as allergens in the German-MAS birth cohort, Olympia Tsilochristou, Alexander Rohrbach, Antonio Cappella, Stephanie Hofmaier, Laura Hatzler, Carl-Peter Bauer, Ute Hoffmann, Johannes Forster, Fred Zepp, Antje Schuster, RaffaeleD’Amelio, Ulrich Wahn, Thomas Keil, Susanne Lau, Paolo Maria Matricardi, PD20 Early life colonization with Lactobacilli and Staphylococcus aureus oppositely associates with the maturation and activation of FOXP3+ CD4 T-cells, Sophia Björkander, Maria A. Johansson, Gintare Lasaviciute, Eva Sverremark-Ekström, PD21 Genome-wide meta-analysis identifies 7 susceptibility loci involved in the atopic march, Ingo Marenholz, Jorge Esparza-Gordillo, Franz RĂŒschendorf, Anja Bauerfeind, David P. Strachan, Ben D. Spycher, Hansjörg Baurecht, Patricia Margaritte-Jeannin, Annika SÀÀf, Marjan Kerkhof, Markus Ege, Svetlana Baltic, Melanie C Matheson, Jin Li, Sven Michel, Wei Q. Ang, Wendy McArdle, Andreas Arnold, Georg Homuth, Florence Demenais, Emmanuelle Bouzigon, Cilla SöderhĂ€ll, Göran Pershagen, Johan C. de Jongste, Dirkje S Postma, Charlotte Braun-FahrlĂ€nder, Elisabeth Horak, Ludmila M. Ogorodova, Valery P. Puzyrev, Elena Yu Bragina, Thomas J Hudson, Charles Morin, David L Duffy, Guy B Marks, Colin F Robertson, Grant W Montgomery, Bill Musk, Philip J Thompson, Nicholas G. Martin, Alan James, Patrick Sleiman, Elina Toskala, Elke Rodriguez, Regina Fölster-Holst, Andre Franke, Wolfgang Lieb, Christian Gieger, Andrea Heinzmann, Ernst Rietschel, Thomas Keil, Sven Cichon, Markus M Nöthen, Craig E Pennell, Peter D Sly, Carsten O Schmidt, Anja Matanovic, Valentin Schneider, Matthias Heinig, Norbert HĂŒbner, Patrick G. Holt, Susanne Lau, Michael Kabesch, Stefan Weidinger, Hakon Hakonarson, Manuel AR Ferreira, Catherine Laprise, Maxim B. Freidin, Jon Genuneit, Gerard H Koppelman, Erik MelĂ©n, Marie-HĂ©lĂšne Dizier, A. John Henderson, Young Ae Lee, POSTER DISCUSSION SESSION 4: Food allergy—Anaphylaxis (PD22–PD26), PD22 Atopy patch test in food protein induced enterocolitis caused by solid food, Purificacion GonzĂĄlez-Delgado, Esther CaparrĂłs, Fernando Clemente, Begoña Cueva, Victoria M. Moreno, Jose Luis Carretero, Javier FernĂĄndez, PD23 Watermelon allergy: a novel presentation, Kate Swan, George Du Toit, PD24 A pilot study evaluating the usefulness of a guideline template for managing milk allergy in primary care, Mudiyur Gopi, Tim Smith, Edara Ramesh, Arun Sadasivam, PD26 Efficacy and safety of cow’s milk oral immunotherapy protocol, InĂȘs Mota, Filipe Benito Garcia, Susana Piedade, Angela Gaspar, Graça Sampaio, Cristina ArĂȘde, LuĂ­s Miguel Borrego, Graça Pires, Cristina Santa-Marta, MĂĄrio Morais-Almeida, POSTER DISCUSSION SESSION 5: Prevention and treatment—Allergy (PD27–PD36), PD27 Allergy-protection by the lactic acid bacterium Lactococcus lactis G121: mode-of-action as revealed in a murine model of experimental allergy, Stephanie Brand, Karina Stein, Holger Heine, Marion Kauth, PD29 The relationship between quality of life and morning salivary cortisol after acute bronchiolitis in infancy, Leif Bjarte Rolfsjord, Egil Bakkeheim, Johan Alm, HĂ„vard Ove Skjerven, Kai-HĂ„kon Carlsen, Jon Olav Hunderi, Teresa LĂžvold Berents, Petter Mowinckel, Karin C. LĂždrup Carlsen, PD30 Randomised trial of the efficacy of MP29-02* compared with fluticasone propionate nasal spray in children aged ≄6 years to <12 years with allergic rhinitis, Ulrich Wahn, Ullrich Munzel, William Berger, PD31 10 mg of oral bilastine in 2 to 11 years old children has similar exposure to the adult therapeutic dose (20 mg), Ulrich Wahn, RomĂĄn Valiente, Valvanera Vozmediano, John C. Lukas, MĂłnica RodrĂ­guez, PD33 Daily symptoms, nocturnal symptoms, activity limitations and reliever therapies during the three steps of IOEASMA programme: a comparison, Sebastiano Guarnaccia, Luigi Vitale, Ada Pluda, Emanuele D’Agata, Denise Colombo, Stefano Felici, Valeria Gretter, Susanna Facchetti, Gaia Pecorelli, Cristina Quecchia, PD34 Sensitisation to an inert aeroallergen in weaning rats and longstanding disease, in a sensitisation-tolerant and easily tolerisable rodent strain, George Guibas, Evangelia Spandou, Spyridon Megremis, Peter West, Nikolaos Papadopoulos, PD35 Bacterial and fungi exposure in school and allergic sensitisation in children, JoĂŁo Cavaleiro Rufo, Joana Madureira, InĂȘs PaciĂȘncia, LĂ­via Aguiar, PatrĂ­cia PadrĂŁo, Mariana Pinto, LuĂ­s Delgado, Pedro Moreira, JoĂŁo Paulo Teixeira, Eduardo Oliveira Fernandes, AndrĂ© Moreira, PD36 Comparative study of allergy rhinitis between two populations: children vs. adults, Adriana Izquierdo Dominguez, Antonio Valero, Joaquim Mullol, Alfonso Del Cuvillo, Javier Montoro, Ignacio Jauregui, Joan Bartra, Ignacio Davila, Marta Ferrer, Joaquin Sastre, POSTER VIEWING SESSION 1: Inflammation—Genetics—Immunology—Dermatology (PP01–PP09), PP01 Immune profile in late pregnancy: immunological markers in atopic asthmaticwomen as risk factors for atopy in the progeny, Catarina Martins, Jorge Lima, Maria JosĂ© Leandro, GlĂłria Nunes, Jorge Cunha Branco, HĂ©lder Trindade, Luis Miguel Borrego, PP02 The impact of neonatal sepsis on development of allergic diseases, Secil Conkar, Mehtap Kilic, Canan Aygun, Recep Sancak, PP03 Clinical overview of selective IgE deficiency in childhood, Athina Papadopoulou, Eleni Tagalaki, Lambros Banos, Anna Vlachou, Fotini Giannoula, Despina Mermiri, PP04 Inverse relationship between serum 25(ΟΗ) vitamin D3 and total IgE in children and adolescence, Athina Papadopoulou, Stavroula Lampidi, Marina Pavlakou, Maria Kryoni, Kostas Makris, PP05, PP06, PP07 Asthma control questionnaire and specific IgE in children, Snezhina Lazova, Guergana Petrova, Dimitrinka Miteva, Penka Perenovska, PP08 Features of chronic urticaria of adolescents, Aliya Klyucharova, Olesya Skorohodkina, PP09 Cutaneous mastocytosis in children: a clinical analysis of 8 cases in Greece, Dimitra Koumaki, Alkisti Manousaki, Maria Agrapidi, Lida Iatridou, Omima Eruk, Konstantinos Myridakis, Emmanouil Manousakis, Vasiliki Koumaki, POSTER VIEWING SESSION 2: Food allergy—Anaphylaxis (PP10–PP47), PP10 Prognostic factors in egg allergy, Maria Dimou, Maria Ingemansson, Gunilla Hedlin, PP11 Evaluation of the efficacy of an amino acid-based formula in infants who are intolerant to extensively hydrolysed protein formula, Nitida Pastor, Delphine de Boissieu, Jon Vanderhoof, Nancy Moore, Kaitlin Maditz, PP12 Anaphylaxis and epinephrine auto-injector use: a survey of pediatric trainees, Adeli Mehdi, Shaza Elhassan, Carolin Beck, Ahmed Al-Hammadi, PP13 Anaphylaxis in children: acute management in the Emergency Department, Ioana Maris, Ronan O’Sullivan, Jonathan Hourihane,, PP14 Understanding Cumbrian schools preparedness in managing children at risk of anaphylaxis in order to provide training and support which will create healthy and safe environments for children with allergies, George Raptis, Louise Michaelis, PP15 A new valid and reliable parent and child questionnaire to measure the impact of food protein enterocolitis syndrome on children: the FPIES Quality of Life Questionnaire (FPIESQL), Parent and Child Short Form, Audrey DunnGalvin, Matthew Greenhawt, Carina Venter, Jonathan Hourihane, PP16 An in-depth case study investigation of the experiences of teenagers and young adults in growing up and living with food allergy with emphasis on coping, management and risk, support, and social and self-identity, Evelyn O’Regan, Duncan Cronin, Jonathan Hourihane, Anna O’Reilly, Audrey DunnGalvin, PP17 Cow’s milk protein allergy in Constantine. A retrospective study of 62 cases between 1996 and 2013, Foued Abdelaziz, Dounia Khelifi-Touhami, Nihad Selim, Tahar Khelifi-Touhami, PP18, PP19 Cow’s milk and egg oral immunotherapy in children older than 5 years, Pablo Merida, Ana MÂȘ Plaza, Juan Heber Castellanos, Adrianna Machinena, Montserrat Alvaro Lozano, Jaime Lozano, Olga Dominguez, Monica Piquer, Rosa Jimenez, MÂȘ Teresa Giner, PP20 Professionals’ awareness of management of Cow’s Milk Protein Allergy (CMPA) in North Wales Hospitals, Konstantinos Kakleas, Manohar Joishy, Wendmu Maskele, Huw R. Jenkins, PP21, PP22 Anaphylaxis: the great unknown for teachers. Presentation of a protocol for schools, Mercedes Escarrer, AgustĂ­n Madroñero, Maria Teresa Guerra, Juan Carlos Julia, Juan Carlos Cerda, Javier Contreras, Eulalia Tauler, Maria Jesus Vidorreta, Ana Rojo, Silvia Del Valle, PP23 Challenges facing children with food allergies and their parents in out of school activity sectors, Niamh Flynn, PP24 A review of food challenges at a Regional Irish Centre, Gary Foley, Carol Harmon, John Fitzsimons, PP25 The use of epinephrine in infants with anaphylaxis, Krasimira Baynova, Ávila Maria Del Robledo, Labella Marina, PP26, PP27, PP28 Mother’s psychological state predicts the expression of symptoms in food allergic children, Aaron Cortes, Alicia Sciaraffia, Angela Castillo, PP29 The correlation between sIgE towards tree nuts and birch pollen in a Danish Pediatric Allergy Clinic, Nanna Juel-Berg, Kirsten Skamstrup Hansen, Lars KĂŠrgaard Poulsen, PP30 Food allergy in children: evaluation of parents’ use of online social media, Andreia Florina Nita, Ioana Valentina Nenciu, Adina Lazar, Dumitru Oraseanu, PP31 The impact of food allergy on quality of life: FAQLQ questionnaire, Rita Aguiar, Anabela Lopes, Maria J. Paes, AmĂ©lia S. Santos, M. A. Pereira-Barbosa, PP32 An unexpected cause of anaphylaxis: potato, Hatice Eke Gungor, Salih Uytun, Umit Murat Sahiner, Yasemin Altuner Torun, PP33 Is it clinical phenotype of allergic diseases determined by sensitisation to food?, Mirjana Zivanovic, Marina Atanasković-Marković, PP34, PP35 Prescribing adrenaline auto-injectors in children in 2014: the data from regional pediatricians, Tina Vesel, Mihaela Nahtigal, Andreja Obermayer-Temlin, Eva Ć oster KriĆŸnik, Mirjana Maslar, Ruben Bizjak, Marjeta TomĆĄič-Matic, Sonja Posega-Devetak, Maja Skerbinjek-Kavalar, Mateja Predalič, Tadej Avčin, PP36 Who should have an adrenaline autoinjector? Adherence to the European and French guidelines among 121 allergists from the Allergy Vigilance Network, Guillaume Pouessel, Etienne Beaudouin, Anne M. Moneret-Vautrin, Antoine Deschildre, Allergy Vigilance Network, PP37 Anaphylaxis by Anacardium Occidentale, Marta Viñas, BartolomĂ© Borja, Nora HernĂĄndez, MÂȘ JosĂ© Castillo, Adriana Izquierdo, Marcel Ibero, PP38 Anaphylaxis with honey in a child, S. Tolga Yavuz, Ali Gungor, Betul Buyuktiryaki, Ozan Koc, Can Naci Kocabas, Faysal Gok, PP39 Evaluation of courses adopted to children on prevention, recognition and management of anaphylaxis, Tina Vesel, Mihaela Nahtigal, PP40 Symptomatic dust mites and shrimp allergy: three pediatric case reports, Filipa Almeida, Susana Lopes, Cristina Madureira, TĂąnia Lopes, Fernanda Carvalho, PP41 Poor identification rates of nuts by high risk individuals: a call for improved education and support for families, Camille Heming, Emily Garrett, Adam Blackstock, Santanu Maity, Rahul Chodhari, PP42 DAFALL: database of food allergies in the Czech Republic, Simona Belohlavkova, Eliska Kopelentova, Petr Visek, Ivana Setinova, Ivana Svarcova, PP43 Serological cross-reactivity between grass and wheat is not only caused by profilins and CCDs, Sigrid Sjölander, Nora Nilsson, Malin Berthold, Helena Ekoff, Gunilla Hedlin, Magnus Borres, Caroline Nilsson, PP44 Oil body associated proteins in children with nuts allergy. Allergens to consider in IgE-mediated nuts allergy, Loreto GonzĂĄlez DomĂ­nguez, Cristina Muñoz Archidona, Ana Moreira Jorge, Sergio Quevedo Teruel, Teresa Bracamonte Bermejo, Miriam Castillo FernĂĄndez, Fernando Pineda de la Losa, Luis Ángel EcheverrĂ­a Zudaire, PP45, PP46 Protective effect of helicobacter pylori infection against food allergy in children, Olga Vrani, Antigone Mavroudi, Maria Fotoulaki, Maria Emporiadou, Kleomenis Spiroglou, Ioannis Xinias, PP47 Anaphylaxis pathway: A road tryp-tase to success?, Helyeh A. Sadreddini, Mia Warnes, Donna Traves, POSTER VIEWING SESSION 3: Miscell
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