6 research outputs found
Structure of multiphoton quantum optics. II. Bipartite systems, physical processes, and heterodyne squeezed states
Extending the scheme developed for a single mode of the electromagnetic field
in the preceding paper ``Structure of multiphoton quantum optics. I. Canonical
formalism and homodyne squeezed states'', we introduce two-mode nonlinear
canonical transformations depending on two heterodyne mixing angles. They are
defined in terms of hermitian nonlinear functions that realize heterodyne
superpositions of conjugate quadratures of bipartite systems. The canonical
transformations diagonalize a class of Hamiltonians describing non degenerate
and degenerate multiphoton processes. We determine the coherent states
associated to the canonical transformations, which generalize the non
degenerate two--photon squeezed states. Such heterodyne multiphoton squeezed
are defined as the simultaneous eigenstates of the transformed, coupled
annihilation operators. They are generated by nonlinear unitary evolutions
acting on two-mode squeezed states. They are non Gaussian, highly non
classical, entangled states. For a quadratic nonlinearity the heterodyne
multiphoton squeezed states define two--mode cubic phase states. The
statistical properties of these states can be widely adjusted by tuning the
heterodyne mixing angles, the phases of the nonlinear couplings, as well as the
strength of the nonlinearity. For quadratic nonlinearity, we study the
higher-order contributions to the susceptibility in nonlinear media and we
suggest possible experimental realizations of multiphoton conversion processes
generating the cubic-phase heterodyne squeezed states.Comment: 16 pages, 23 figure
Multiphoton Quantum Optics and Quantum State Engineering
We present a review of theoretical and experimental aspects of multiphoton
quantum optics. Multiphoton processes occur and are important for many aspects
of matter-radiation interactions that include the efficient ionization of atoms
and molecules, and, more generally, atomic transition mechanisms;
system-environment couplings and dissipative quantum dynamics; laser physics,
optical parametric processes, and interferometry. A single review cannot
account for all aspects of such an enormously vast subject. Here we choose to
concentrate our attention on parametric processes in nonlinear media, with
special emphasis on the engineering of nonclassical states of photons and
atoms. We present a detailed analysis of the methods and techniques for the
production of genuinely quantum multiphoton processes in nonlinear media, and
the corresponding models of multiphoton effective interactions. We review
existing proposals for the classification, engineering, and manipulation of
nonclassical states, including Fock states, macroscopic superposition states,
and multiphoton generalized coherent states. We introduce and discuss the
structure of canonical multiphoton quantum optics and the associated one- and
two-mode canonical multiphoton squeezed states. This framework provides a
consistent multiphoton generalization of two-photon quantum optics and a
consistent Hamiltonian description of multiphoton processes associated to
higher-order nonlinearities. Finally, we discuss very recent advances that by
combining linear and nonlinear optical devices allow to realize multiphoton
entangled states of the electromnagnetic field, that are relevant for
applications to efficient quantum computation, quantum teleportation, and
related problems in quantum communication and information.Comment: 198 pages, 36 eps figure
Mathematical model of an off-grid hybrid solar and wind power generating system
The dynamics of an off-grid power generating system, coupled to a storage unit
and to household appliances, is described by means of an analytic hydrodynamic analog.
Following this analogy, by noticing that the efflux rate from a leaking bucket is described,
in terms of the liquid content, by Torricelliâs formula, we denote as âTorricelliâs smart
consumerâ a user being able to calibrate its energy consumption rate with respect to the
energy level in the storage unit as if the hydrodynamic model would strictly apply. Simple
solutions to the nonlinear dynamic problem associated to this type of smart consumer are
found and generalization to other types of smart consumers are sought
Structure of multiphoton quantum optics. I. Canonical formalism and homodyne squeezed states
Remote control of induced dopaminergic neurons in parkinsonian rats
Direct lineage reprogramming through genetic-based strategies enables the conversion of differentiated somatic cells into functional neurons and distinct neuronal subtypes. Induced dopaminergic (iDA) neurons can be generated by direct conversion of skin fibroblasts; however, their in vivo phenotypic and functional properties remain incompletely understood, leaving their impact on Parkinson's disease (PD) cell therapy and modeling uncertain. Here, we determined that iDA neurons retain a transgene-independent stable phenotype in culture and in animal models. Furthermore, transplanted iDA neurons functionally integrated into host neuronal tissue, exhibiting electrically excitable membranes, synaptic currents, dopamine release, and substantial reduction of motor symptoms in a PD animal model. Neuronal cell replacement approaches will benefit from a system that allows the activity of transplanted neurons to be controlled remotely and enables modulation depending on the physiological needs of the recipient; therefore, we adapted a DREADD (designer receptor exclusively activated by designer drug) technology for remote and real-time control of grafted iDA neuronal activity in living animals. Remote DREADD-dependent iDA neuron activation markedly enhanced the beneficial effects in transplanted PD animals. These data suggest that iDA neurons have therapeutic potential as a cell replacement approach for PD and highlight the applicability of pharmacogenetics for enhancing cellular signaling in reprogrammed cell-based approaches