First detection in Europe of the metallo-β-lactamase IMP-15 in clinical strains of Pseudomonas putida and Pseudomonas aeruginosa

AbstractIn a prospective study (2009–2011) in healthcare institutions from the Canary Islands (Spain), 6 out of 298 carbapenem non-susceptible Pseudomonas aeruginosa isolates produced a metallo-β-lactamase: four IMP-15, two VIM-2 (including one IMP-15-positive isolate) and one VIM-1. Multilocus sequence typing identified the single VIM-1-producing isolate as clone ST111 and two IMP-15-producing isolates as ST606, but, strikingly, bacterial re-identification revealed that the other three isolates (producing IMP-15 and/or VIM-2) were actually Pseudomonas putida. Further retrospective analysis revealed a very high prevalence (close to 50%) of carbapenem resistance in this environmental species. Hence, we report the simultaneous emergence in hospitals on the Canary Islands of P. putida and P. aeruginosa strains producing IMP-15, a metallo-β-lactamase not previously detected in Europe, and suggest an underestimated role of P. putida as a nosocomial reservoir of worrying transferable resistance determinants

Spin-Flip Noise in a Multi-Terminal Spin-Valve

We study shot noise and cross correlations in a four terminal spin-valve geometry using a Boltzmann-Langevin approach. The Fano factor (shot noise to current ratio) depends on the magnetic configuration of the leads and the spin-flip processes in the normal metal. In a four-terminal geometry, spin-flip processes are particular prominent in the cross correlations between terminals with opposite magnetization.Comment: 4 pages, 3 figure

Triviality from the Exact Renormalization Group

Using the exact renormalization group, it is shown that no physically acceptable non-trivial fixed points, with positive anomalous dimension, exist for (i) O(N) scalar field theory in four or more dimensions, (ii) non-compact, pure Abelian gauge theory in any dimension. It is then shown, for both theories in any dimension, that otherwise physically acceptable non-trivial fixed points with negative anomalous dimension are non-unitary. In addition, a very simple demonstration is given, directly from the exact renormalization group, that should a critical fixed point exist for either theory in any dimension, then the n-point correlation functions exhibit the expected behaviour.Comment: 14 pages, 6 figures; v2: Important addition - negative anomalous dimensions now treated; v3: error in treatment of negative anomalous dimension corrected and some clarifications added; v4: published in JHEP; very minor change

Ultraviolet sensitivity of rare decays in nonuniversal extra dimensional models

We consider a nonuniversal five dimensional model in which fermions are localised on a four dimensional brane, while gauge bosons and a scalar doublet can travel in the bulk. As a result of KK number non-conservation at the brane-bulk intersection, the ultraviolet divergence does not cancel out in some physical observables. For example, the $B_d \to l^+l^-$ decay amplitude is linearly divergent, while $B$--$\bar{B}$ mixing amplitude is log divergent. We attempt to identify the exact source of this nonrenormalizability. We compare and contrast our results with those obtained in the universal five dimensional model where all particles travel in the extra dimension.Comment: Latex, 11 pages, uses axodraw.st

Monitoring the antimicrobial susceptibility of Gramnegative organisms involved in intraabdominal and urinary tract infections recovered during the SMART study (Spain, 2016 and 2017)

OBJECTIVE: Continuous antimicrobial resistance surveillance is recommended by Public Health authorities. We up-dated data from the SMART (Study for Monitoring Antimicrobial Resistance Trends) surveillance study in Spain. METHODS: The antimicrobial susceptibility data and extended-spectrum beta-lactamase (ESBL) production in isolates recovered from intra-abdominal (IAI) (n=1,429) and urinary tract (UTI) (n=937) infections during the 2016- 2017 SMART study in 10 Spanish hospitals were analysed. RESULTS: Escherichia coli was the most frequently microorganism isolated (48.3% and 53.7%) followed by Klebsiella spp. (11.5% and 21.9%) in IAIs and UTIs, respectively. Figures for Pseudomonas aeruginosa were 9.0% and 6.1%, being more frequently recovered from patients with nosocomial infections. Overall, 9.9% (IAI) and 14.0% (UTI) of E. coli, Klebsiella spp. and Proteus mirabilis isolates were ESBL-producers, being Klebsiella pneumoniae (34.5%) from UTI of nosocomial origin the most frequent. ESBL-producers were higher in patients >60 years in both IAIs and UTIs. As in previous years, amikacin (96.3%-100% susceptibility), ertapenem (84.2%-100%) and imipenem (70.3%- 100%) were the most active antimicrobials tested among Enterobacterales species. The activity of amoxicillin-clavulanic, piperacillin-tazobactam, and ciprofloxacin susceptibility was lower, particularly among ESBL-producers. Ertapenem susceptibility (88.9%-100%) was retained in ESBL-E. coli isolates that were resistant to these antimicrobials but decreased (28.6%-100%) in similar isolates of K. pneumoniae. CONCLUSIONS: Continuous antimicrobial resistance surveillance from the SMART study reveals overall maintenance of ESBL-producers in Spain, although with higher presence in isolates from UTIs than from IAIs. Moreover, ertapenem activity was high in E. coli irrespective of ESBL production but decreased in K. pneumoniae, particularly among ESBL-producers

Progetti partecipativi per la (ri)costruzione collettiva della Vega de Granada come territorio agricolo periurbano

The impaired condition of agriculture, and of periurban agricultural areas in particular, necessarily requires a switch in the direction imposed by the contemporary metropolitan model, using the opportunities offered by social participation, meant as territorial government ruled by citizenship, as turning point. On the basis of this statement, the Granada metropolitan area, and in particular the irrigated plane (la Vega) that gives it sense and landscape identity, is approached through participatory projects trying to identify conflicts, values and perspectives of a sustainable future for these territories.La situazione deteriorata dell’agricoltura e, in particolare, degli spazi agricoli periurbani, implica la necessità di un cambio di direzione, rispetto a quella imposta dal modello metropolitano contemporaneo, che parta dalle opportunità offerte dalla partecipazione sociale intesa come governo del territorio da parte della cittadinanza. Sulla base di questa premessa si affronta l’area metropolitana di Granada e, in particolare, la piana irrigua che le conferisce senso e identità paesistica (la Vega) utilizzando progetti partecipativi finalizzati all’identificazione dei conflitti, dei valori e delle prospettive di un futuro sostenibile per questo territorio

Measurement of the polarisation of W bosons produced with large transverse momentum in pp collisions at sqrt(s) = 7 TeV with the ATLAS experiment

This paper describes an analysis of the angular distribution of W->enu and W->munu decays, using data from pp collisions at sqrt(s) = 7 TeV recorded with the ATLAS detector at the LHC in 2010, corresponding to an integrated luminosity of about 35 pb^-1. Using the decay lepton transverse momentum and the missing transverse energy, the W decay angular distribution projected onto the transverse plane is obtained and analysed in terms of helicity fractions f0, fL and fR over two ranges of W transverse momentum (ptw): 35 < ptw < 50 GeV and ptw > 50 GeV. Good agreement is found with theoretical predictions. For ptw > 50 GeV, the values of f0 and fL-fR, averaged over charge and lepton flavour, are measured to be : f0 = 0.127 +/- 0.030 +/- 0.108 and fL-fR = 0.252 +/- 0.017 +/- 0.030, where the first uncertainties are statistical, and the second include all systematic effects.Comment: 19 pages plus author list (34 pages total), 9 figures, 11 tables, revised author list, matches European Journal of Physics C versio

Observation of a new chi_b state in radiative transitions to Upsilon(1S) and Upsilon(2S) at ATLAS

The chi_b(nP) quarkonium states are produced in proton-proton collisions at the Large Hadron Collider (LHC) at sqrt(s) = 7 TeV and recorded by the ATLAS detector. Using a data sample corresponding to an integrated luminosity of 4.4 fb^-1, these states are reconstructed through their radiative decays to Upsilon(1S,2S) with Upsilon->mu+mu-. In addition to the mass peaks corresponding to the decay modes chi_b(1P,2P)->Upsilon(1S)gamma, a new structure centered at a mass of 10.530+/-0.005 (stat.)+/-0.009 (syst.) GeV is also observed, in both the Upsilon(1S)gamma and Upsilon(2S)gamma decay modes. This is interpreted as the chi_b(3P) system.Comment: 5 pages plus author list (18 pages total), 2 figures, 1 table, corrected author list, matches final version in Physical Review Letter

Search for displaced vertices arising from decays of new heavy particles in 7 TeV pp collisions at ATLAS

We present the results of a search for new, heavy particles that decay at a significant distance from their production point into a final state containing charged hadrons in association with a high-momentum muon. The search is conducted in a pp-collision data sample with a center-of-mass energy of 7 TeV and an integrated luminosity of 33 pb^-1 collected in 2010 by the ATLAS detector operating at the Large Hadron Collider. Production of such particles is expected in various scenarios of physics beyond the standard model. We observe no signal and place limits on the production cross-section of supersymmetric particles in an R-parity-violating scenario as a function of the neutralino lifetime. Limits are presented for different squark and neutralino masses, enabling extension of the limits to a variety of other models.Comment: 8 pages plus author list (20 pages total), 8 figures, 1 table, final version to appear in Physics Letters