Gambaran Neuropati Perifer pada Diabetisi di Wilayah Kerja Puskesmas Kedungmundu Semarang

Peripheral neuropathy is one of microvascular complications of DM (Diabetes Mellitus) that happens on peripheral section and causes the nerves dysfunction. This nerves dysfunction can affect sensoric, motoric, and autonomic nerve function. The aims of this study was to describe peripheral neuropathy on diabetics in Puskesmas Kedungmundu Semarang. This study was a descriptive quantitative model using cross sectional approach. Total population sampling was used in this study. There were observation sheets that was modified from MNSI (Michigan Neuropathy Screening Instrument) and MDNS (Michigan Diabetic Neuropathy Score) consist of 38 contens. Univariat analysis was used in this study. A total of 113 respondents had been participated in this study. The result showed that the majority of respondents were in the midle-adult diabetics (73.5%), female (61,9%), have diabetes for more than 5 years (50.4%), and have random glucose level ≥200 mg/dL (52.2%). Some of diabetics have other disease, amputation history, and DFU (Diabetic Foot Ulcer) history (29.2%, 3.5%, 5.3%). The nerves dysfunction are mostly founded in autonomic dysfunction, either on right or left foot. There were more diabetics with mild neuropathy (55.8%) compared to diabetics with moderate or severe neuropathy (28.3% ; 9.7%). This study concluded that the majority of respondents have peripheral neuropathy. Therefore, early assessment is needed to prevent stage severity of peripheral neuropathy

Systematic study of the effect of short range correlations on the form factors and densities of s-p and s-d shell nuclei

Analytical expressions of the one- and two-body terms in the cluster expansion of the charge form factors and densities of the s-p and s-d shell nuclei with N=Z are derived. They depend on the harmonic oscillator parameter b and the parameter $\beta$ which originates from the Jastrow correlation function. These expressions are used for the systematic study of the effect of short range correlations on the form factors and densities and of the mass dependence of the parameters b and $\beta$. These parameters have been determined by fit to the experimental charge form factors. The inclusion of the correlations reproduces the experimental charge form factors at the high momentum transfers ($q\geq 2 1/fm$). It is found that while the parameter $\beta$ is almost constant for the closed shell nuclei, $^4$He, $^{16}$O and $^{40}$Ca, its values are larger (less correlated systems) for the open shell nuclei, indicating a shell effect in the closed shell nuclei.Comment: Latex, 21 pages, 6 figures, 1 tabl

Kenali, Cegah dan Atasi Dislipidemia Recognize, Prevent, and Eradicate Dyslipidemia

Dislipidemia adalah kelainan metabolisme lipid yang ditandai dengan peningkatan maupun penurunan satu atau lebih fraksi lipid dalam darah. Peningkatan kadar kolesterol total dan LDL darah dapat disebabkan oleh peningkatan konsumsi lemak jenuh dan kolesterol yang tinggi dalam makanan. Pada perjalanan dislipidemia, apabila kadar kolesterol tidak terkontrol dengan baik, maka akan meningkatkan risiko terjadi nya komplikasi baik akut maupun kronis. Pada umumnya, sebagian masyarakat telah mengenal perihal kolesterol secara umum namun mungkin belum memahami bagaimana cara mencegah dan mengatasi kadar kolesterol darah yang tinggi. Edukasi yang baik disertai terapi nutrisi, jasmani dan tatalaksana farmakologi diharapkan dapat mengendalikan progresifitas penyakit dislipidemia dan komplikasinya. Oleh karena itu pengabdian masyarakat berbasis webinar ini diadakan selain untuk meningkatkan keilmuan, juga diharapkan dapat meningkatkan kesadaran akan bahaya dari penyakit dislipidemia. Kegiatan webinar ini menargetkan mahasiswa UTA45 dan masyarakat umum dengan luaran yang diharapkan yaitu dapat meningkatkan pengetahuan tentang penyakit dislipidemia. Webinar dengan metode presentasi dan tanya jawab yang dilaksanakan pada 27 April 2022. Total peserta yang mengikuti kegiatan webinar dengan mengisi absen secara online sebanyak 66 peserta. Persentase rata – rata total skor prestest perserta sebesar 70,2% dan rata – rata skor posttest sebesar 79,6% dapat dilihat bahwa terjadi peningkatan skor posttest sebesar 9,4%

'Pregnancy comes accidentally - like it did with me': reproductive decisions among women on ART and their partners in rural Uganda

<p>Abstract</p> <p>Background</p> <p>As highly active antiretroviral therapy (ART) restores health, fertility and sexual activity among HIV-infected adults, understanding how ART influences reproductive desires and decisions could inform interventions to reduce sexual and vertical HIV transmission risk.</p> <p>Methods</p> <p>We performed a qualitative sub-study among a Ugandan cohort of 1,000 adults on ART with four purposively selected categories of participants: pregnant, not pregnant, delivered, and aborted. In-depth interviews examined relationships between HIV, ART and pregnancy, desire for children, perceived risks and benefits of pregnancy, decision-making regarding reproduction and family planning (FP) among 29 women and 16 male partners. Analysis focused on dominant explanations for emerging themes across and within participant groups.</p> <p>Results</p> <p>Among those who had conceived, most couples stated that their pregnancy was unintentional, and often occurred because they believed that they were infertile due to HIV. Perceived reasons for women not getting pregnant included: ill health (included HIV infection and ART), having enough children, financial constraints, fear of mother-to-child HIV transmission or transmission to partner, death of a child, and health education. Most women reported FP experiences with condoms and hormonal injections only. Men had limited FP information apart from condoms.</p> <p>Conclusions</p> <p>Counselling at ART initiation may not be sufficient to enable women who do not desire children to adopt relevant family planning practices. On-going reproductive health education and FP services, with emphasis on the restoration of fertility after ART initiation, should be integrated into ART programs for men and women.</p

The neighbourhood social environment and alcohol use among urban and rural Scottish adolescents

Funding for the Scottish Health Behaviour in School-aged Children was provided by NHS Scotland. This work was also supported by the 600th Anniversary Ph.D. Scholarship which was awarded to Gina Martin by the University of St Andrews.Objectives This research examined the relationship between neighbourhood social environmental characteristics and drinking outcomes among a sample of urban and rural adolescents. Methods From a sample of 1558 Scottish secondary schoolchildren, surveyed as part of the 2010 Health Behaviour in School-aged Children study, we modelled three drinking outcomes on a variety of neighbourhood conditions, including social cohesion, disorder, alcohol outlet density, deprivation, and urban/rurality. Nested and cross-classified multilevel logistic regressions were specified. Results An urban-to-rural gradient was found with non-urban adolescents exhibiting higher odds of having ever drank. Neighbourhood social cohesion related to having ever drank. Among drinkers, those living in accessible small towns had higher odds of weekly drinking and drunkenness compared to urban areas. Higher odds of drunkenness were also found in remote rural areas. Those residing in the least deprived areas had lower odds of weekly drinking. Conclusions In Scotland, inequalities exist in adolescent alcohol use by urban/rurality and neighbourhood social conditions. Findings support regional targeting of public health efforts to address inequalities. Future work is needed to develop and evaluate intervention and prevention approaches for neighbourhoods at risk.Publisher PDFPeer reviewe

Sinteza, spazmolitsko i antidijaretsko djelovanje nekih 1-supstituiranih derivata imidazola

A series of 1-substituted imidazoles 1a-d and 2a-d were synthesized and screened for antispasmodic and antidiarrheal activities. Antispasmodic activity was tested at various concentrations on isolated tissue preparations; concentration-response curves were plotted and compared with atropine. All compounds were found to inhibit contraction of the guinea pig ileum. Castor oil-induced diarrhea model in rats was used for evaluation of antidiarrheal activity. Parameters such as intestinal transit and volume of intestinal fluid were measured for antidiarrheal activity at 40 mg kg-1 dose and compared with the standard drug loperamide at a 6 mg kg1 dose. Defecation frequency in the test group was found to be significantly lower (p < 0.01) compared to the control group and comparable with that of the standard. The present study reveals that the compounds exert antidiarrheal activity through possible inhibition of intestinal movement and reduction of capillary permeability in the abdominal cavity.U radu je opisana sinteza serije novih 1-supstituiranih imidazola 1a-d i 2a-d te evaluacija njihovog spazmolitskog i antidijaretskog djelovanja. Spazmolitsko djelovanje različith koncentracija ispitivanih spojeva (10, 50 i 100 µg mL1) ispitano je na izoliranim tkivnim preparatima; krivulje ovisnosti djelovanja o koncentraciji uspoređene su s djelovanjem atropina. Svi ispitivani spojevi inhibirali su kontrakcije ileuma zamorca. Dijarea inducirana ricinusovim uljem u štakora korištena je za vrednovanje antidijaretskog djelovanja. Intestinalni prijenos i volumen intestinalne tekućine mjereni su pri dozi od 40 mg kg1 i uspoređeni s učinkom standarda loperamida (doza 6 mg kg1). Učestalost defekacije u testiranoj skupini bila je značajno niža (p < 0,01) u usporedbi s kontrolnom skupinom i standardom. Provedena ispitivanja pokazuju da antidijaretsko djelovanje ispitivanih spojeva može biti posljedica inhibicije intestinalnih pokreta i redukcije kapilarne permeabilnosti u abdominalnoj šupljini

Observation of Top Quark Production in Proton-Nucleus Collisions

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