Measurements of differential production cross sections for a Z boson in association with jets in pp collisions at root s=8 TeV

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Search for the associated production of the Higgs boson with a top-quark pair

A search for the standard model Higgs boson produced in association with a top-quark pair t t ¯ H (tt¯H) is presented, using data samples corresponding to integrated luminosities of up to 5.1 fb −1 and 19.7 fb −1 collected in pp collisions at center-of-mass energies of 7 TeV and 8 TeV respectively. The search is based on the following signatures of the Higgs boson decay: H → hadrons, H → photons, and H → leptons. The results are characterized by an observed t t ¯ H tt¯H signal strength relative to the standard model cross section, μ = σ/σ SM ,under the assumption that the Higgs boson decays as expected in the standard model. The best fit value is μ = 2.8 ± 1.0 for a Higgs boson mass of 125.6 GeV

Measurement of prompt Jψ\psi pair production in pp collisions at \sqrt s = 7 Tev

Production of prompt J/ ψ meson pairs in proton-proton collisions at s s√ = 7 TeV is measured with the CMS experiment at the LHC in a data sample corresponding to an integrated luminosity of about 4.7 fb −1 . The two J/ ψ mesons are fully reconstructed via their decays into μ + μ − pairs. This observation provides for the first time access to the high-transverse-momentum region of J/ ψ pair production where model predictions are not yet established. The total and differential cross sections are measured in a phase space defined by the individual J/ ψ transverse momentum ( p T J/ ψ ) and rapidity (| y J/ ψ |): | y J/ ψ | 6.5 GeV/ c ; 1.2 4.5 GeV/ c . The total cross section, assuming unpolarized prompt J/ ψ pair production is 1.49 ± 0.07 (stat) ±0.13 (syst) nb. Different assumptions about the J/ ψ polarization imply modifications to the cross section ranging from −31% to +27%

Measurements of the t(t)Overbar charge asymmetry using the dilepton decay channel in pp collisions at root s=7 TeV

The tt¯ charge asymmetry in proton-proton collisions at s√ = 7 TeV is measured using the dilepton decay channel (ee, e μ , or μμ ). The data correspond to a total integrated luminosity of 5.0 fb −1 , collected by the CMS experiment at the LHC. The tt and lepton charge asymmetries, defined as the differences in absolute values of the rapidities between the reconstructed top quarks and antiquarks and of the pseudorapidities between the positive and negative leptons, respectively, are measured to be A C = −0 . 010 ± 0 . 017 (stat . ) ± 0 . 008 (syst . ) and AlepC = 0 . 009 ± 0 . 010 (stat . ) ± 0 . 006 (syst . ). The lepton charge asymmetry is also measured as a function of the invariant mass, rapidity, and transverse momentum of the tt¯ system. All measurements are consistent with the expectations of the standard model

Vascular Remodeling in Health and Disease

The term vascular remodeling is commonly used to define the structural changes in blood vessel geometry that occur in response to long-term physiologic alterations in blood flow or in response to vessel wall injury brought about by trauma or underlying cardiovascular diseases.1, 2, 3, 4 The process of remodeling, which begins as an adaptive response to long-term hemodynamic alterations such as elevated shear stress or increased intravascular pressure, may eventually become maladaptive, leading to impaired vascular function. The vascular endothelium, owing to its location lining the lumen of blood vessels, plays a pivotal role in regulation of all aspects of vascular function and homeostasis.5 Thus, not surprisingly, endothelial dysfunction has been recognized as the harbinger of all major cardiovascular diseases such as hypertension, atherosclerosis, and diabetes.6, 7, 8 The endothelium elaborates a variety of substances that influence vascular tone and protect the vessel wall against inflammatory cell adhesion, thrombus formation, and vascular cell proliferation.8, 9, 10 Among the primary biologic mediators emanating from the endothelium is nitric oxide (NO) and the arachidonic acid metabolite prostacyclin [prostaglandin I2 (PGI2)], which exert powerful vasodilatory, antiadhesive, and antiproliferative effects in the vessel wall

Charged-particle nuclear modification factors in PbPb and pPb collisions at √=sNN=5.02 TeV

The spectra of charged particles produced within the pseudorapidity window |η| < 1 at √ sNN = 5.02 TeV are measured using 404 µb −1 of PbPb and 27.4 pb−1 of pp data collected by the CMS detector at the LHC in 2015. The spectra are presented over the transverse momentum ranges spanning 0.5 < pT < 400 GeV in pp and 0.7 < pT < 400 GeV in PbPb collisions. The corresponding nuclear modification factor, RAA, is measured in bins of collision centrality. The RAA in the 5% most central collisions shows a maximal suppression by a factor of 7–8 in the pT region of 6–9 GeV. This dip is followed by an increase, which continues up to the highest pT measured, and approaches unity in the vicinity of pT = 200 GeV. The RAA is compared to theoretical predictions and earlier experimental results at lower collision energies. The newly measured pp spectrum is combined with the pPb spectrum previously published by the CMS collaboration to construct the pPb nuclear modification factor, RpA, up to 120 GeV. For pT > 20 GeV, RpA exhibits weak momentum dependence and shows a moderate enhancement above unity

Preference Mapping Of Dulce De Leche Commercialized In Brazilian Markets

Dulce de leche samples available in the Brazilian market were submitted to sensory profiling by quantitative descriptive analysis and acceptance test, as well sensory evaluation using the just-about-right scale and purchase intent. External preference mapping and the ideal sensory characteristics of dulce de leche were determined. The results were also evaluated by principal component analysis, hierarchical cluster analysis, partial least squares regression, artificial neural networks, and logistic regression. Overall, significant product acceptance was related to intermediate scores of the sensory attributes in the descriptive test, and this trend was observed even after consumer segmentation. The results obtained by sensometric techniques showed that optimizing an ideal dulce de leche from the sensory standpoint is a multidimensional process, with necessary adjustments on the appearance, aroma, taste, and texture attributes of the product for better consumer acceptance and purchase. The optimum dulce de leche was characterized by high scores for the attributes sweet taste, caramel taste, brightness, color, and caramel aroma in accordance with the preference mapping findings. In industrial terms, this means changing the parameters used in the thermal treatment and quantitative changes in the ingredients used in formulations.98314431454Albenzio, M., Santillo, A., Caroprese, M., Braghieri, A., Sevi, A., Napolitano, F., Composition and sensory profiling of probiotic Scamorza ewe milk cheese (2013) J. Dairy Sci., 96, pp. 2792-2800Aquino, L.F.M.C., Silva, A.C.O., Freitas, M.Q., Felicio, T.L., Cruz, A.G., Conte-Junior, C.A., Identifying cheese whey an adulterant in milk: Limited contribution of a sensometric approach (2014) Food Res. Int., 62, pp. 233-237Bi, J., A review of statistical methods for determination of relative importance of correlated predictors and identification of drivers of consumer liking (2012) J. Sens. Stud., 27, pp. 87-101Bonanya, J., Brugger, C., Buehler, A., Carbóa, J., Codarin, S., Donati, F., Echeverria, G., Schoorl, F., Preference mapping of apple varieties in Europe (2014) Food Qual. Prefer., 32, pp. 317-329Cadena, R.S., Cruz, A.G., Faria, J.A.F., Bolini, H.M.A., Reduced fat and sugar vanilla ice creams: Sensory profiling and external preference mapping (2012) J. Dairy Sci., 95, pp. 4842-4850Cadena, R.S., Cruz, A.G., Netto, R.R., Castro, W.F., Faria, J.A.F., Bolini, H.M.A., Sensory profile and physicochemical characteristics of mango nectar sweetened with high intensity sweeteners throughout storage time (2013) Food Res. Int., 54, pp. 1670-1679Cetó, X., Gutiérrez-Capitán, M., Calvo, D., Del Valle, M., Beer classification by means of a potentiometric electronic tongue (2013) Food Chem., 141, pp. 2533-2540Cevoli, C., Cerretani, L., Gori, A., Caboni, M.F., Gallina Toschi, T., Fabbri, A., Classification of Pecorino cheeses using electronic nose combined with artificial neural network and comparison with GC-MS analysis of volatile compounds (2011) Food Chem., 129, pp. 1315-1319Chollet, M., Gille, D., Schmid, A., Walther, B., Piccinali, P., Acceptance of sugar reduction in flavored yogurt (2013) J. Dairy Sci., 96, pp. 5501-5511Cruz, A.G., Cadena, R.S., Castro, W.F., Esmerino, E.A., Rodrigues, J.B., Gaze, L., Faria, J.A.F., Bolini, H.M.A., Consumer perception of probiotic yogurt: Performance of check all that apply (CATA), projective mapping, sorting and intensity scale (2013) Food Res. Int., 54, pp. 601-610Cruz, A.G., Cadena, R.S., Faria, J.A.F., Bolini, M.A., Dantas, C., Ferreira, M.M.C., Deliza, R., PARAFAC: Adjustment for modeling consumer study covering probiotic and conventional yogurt (2012) Food Res. Int., 45, pp. 211-215Cruz, A.G., Cadena, R.S., Faria, J.A.F., Oliveira, C.A.F., Cavalcanti, R.N., Bona, E., Silva, M.A.A.P., Consumer acceptability and purchase intent of probiotic yoghurt with added glucose oxidase using sensometrics, artificial neural networks and logistic regression (2011) Int. J. Dairy Technol., 64, pp. 549-556Cruz, A.G., Walter, E.H.M., Cadena, R.S., Faria, J.A.F., Bolini, H.M.A., Frattini Fileti, A.M., Monitoring the authenticity of low-fat yogurts by an artificial neural network (2009) J. Dairy Sci., 92, pp. 4797-4804Donadini, D., Fumi, M.D., Valoni, L., Porreta, S., Hedonic response to cheese in preschoolers (2012) J. Sens. Stud., 27, pp. 176-187Drake, S.L., Lopetcharat, K., Drake, M.A., Salty taste in dairy foods: Can we reduce the salt? (2011) J. Dairy Sci., 94, pp. 636-645Ennis, D.M., Ennis, J.M., Mapping hedonic data: A process perspective (2013) J. Sens. Stud., 28, pp. 324-334Gaze, L.V., Costa, M.P., Monteiroa, M.L.G., Lavoratoc, J.A.A., Conte Júniora, C.A., Raicesb, R.S.L., Cruzb, A.G., Freitas, M.Q., Dulce de Leche, a typical product of Latin America: Characterization by physicochemical, optical and instrumental methods (2015) Food Chem., 169, pp. 471-477Giménez, A., Ares, G., Gámbaro, A., Consumer perception of sandiness in Dulce de leche (2008) J. Sens. Stud., 23, pp. 171-185Granato, D., Calado, V.M.A., Jarvis, B., Observations on the use of statistical methods in food science and technology (2014) Food Res. Int., 55, pp. 137-149Heymann, H., Machado, B., Torri, L., Robinson, A.L., How many judges should one used for sensory descriptive analysis? (2012) J. Sens. Stud., 27, pp. 111-122Kaaki, D., Kebbe Baghdadi, O., Najm, N.E., Olabi, A., Preference mapping of commercial Labneh (strained yogurt) products in the Lebanese market (2012) J. Dairy Sci., 95, pp. 521-532Macfie, H.J., Bratchell, N., Greenhoff, K., Vallis, L., Designs to balance the effect of order of presentation and first-order carry-over effects in hall tests (1989) J. Sens. Stud., 4, pp. 129-148(2013) Understanding penalty analysis, , http://http://www.marketresearchworld.net/content/view/3233/74/, Accessed June 08, 2014Morais, E.C., Cruz, A.G., Faria, J.A.F., Bolini, H.M.A., Prebiotic gluten-free bread: Sensory profiling and drivers of liking (2014) Lebenson. Wiss. Technol., 55, pp. 248-254Morais, E.C., Morais, A.R., Cruz, A.G., Bolini, H.M.A., Development of chocolate dairy dessert with addition of prebiotics and replacement of sucrose with different high-intensity sweeteners (2014) J. 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Dairy Sci., 97, pp. 3262-3272Perrone, I.T., Stephani, R., Neves, B.S., (2011) Doce de Leite: Aspectos Tecnológicos, , Instituto de Laticínios Cândido Tostes, Juiz de Fora, BrazilPerrone, I.T., Stephani, R., Neves, B.S., Sá, J.F.O., Carvalho, A.F., Technological control for doce de leite production (2014) Indústria de Laticínios, 107, pp. 54-61Pimentel, T.C., Cruz, A.G., Prudencio, S.H., Influence of long-chain inulin and Lactobacillusparacasei subspecies paracasei on the sensory profile and acceptance of a traditional yogurt (2013) J. Dairy Sci., 96, pp. 6233-6241Prinyawiwatkul, W., Chompreeda, P., Applications of discriminant and logistic regression analysis for consumer acceptance and consumer-oriented product optimization study (2007) Accelerating New Food Product Design and Development, pp. 279-295. , Blackwell Professional Publishing, Ames, IA, J.H. Beckley (Ed.)Resano, H., Sanjuán, A.I., Cilla, I., Roncalés, P., Albisu, L.M., Sensory attributes that drive consumer acceptability of dry-cured ham and convergence with trained sensory data (2010) Meat Sci., 84, pp. 344-351Stone, H., Bleibaum, R.N., Thomas, H.A., (2012) Sensory Evaluation Practices, , Elsevier, New York, NYVidigal, M.C.T.R., Minim, V.P.R., Carvalho, N.B., Milagres, M.P., Gonçalves, A.C.A., Effect of a health claim on consumer acceptance of exotic Brazilian fruit juices: Açaí (Euterpe oleracea Mart.), Camu-camu (Myrciaria dubia), Cajá (Spondias lutea L.) and Umbu (Spondias tuberosa Arruda) (2011) Food Res. Int., 44, pp. 1988-1996Villegas, B., Tárrega, A., Carbonell, I., Costell, E., Optimising acceptability of new prebiotic low-fat milk beverages (2010) Food Qual. 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Emergence Of Extended-spectrum β-lactamase Producing Enterobacter Spp. In Patients With Bacteremia In A Tertiary Hospital In Southern Brazil

Background Extended-spectrum β-lactamases (ESBLs) are increasingly prevalent in Enterobacter spp., posing a challenge to the treatment of infections caused by this microorganism. The purpose of this retrospective study was to evaluate the prevalence, risk factors, and clinical outcomes of inpatients with bacteremia caused by ESBL and non ESBL-producing Enterobacter spp. in a tertiary hospital over the period 2004-2008. Methods The presence of blaCTX-M, blaTEM, blaSHV, and blaPER genes was detected by polymerase chain reaction (PCR) and nucleotide sequence analysis. Genetic similarity between strains was defined by pulsed-field gel electrophoresis (PFGE). Results Enterobacter spp. was identified in 205 of 4907 of the patients who had positive blood cultures during hospitalization. Of those cases, 41 (20%) were ESBL-producing Enterobacter spp. Nosocomial pneumonia was the main source of bacteremia caused by ESBL-producing Enterobacter spp. The presence of this microorganism was associated with longer hospital stays. The ESBL genes detected were: CTX-M-2 (23), CTX-M-59 (10), CTX-M-15 (1), SHV-12 (5), and PER-2 (2). While Enterobacter aerogenes strains showed mainly a clonal profile, Enterobacter cloacae strains were polyclonal. Conclusion Although no difference in clinical outcomes was observed between patients with infections by ESBL-producing and non-ESBL-producing strains, the detection of ESBL in Enterobacter spp. resulted in the change of antimicrobials in 75% of cases, having important implications in the decision-making regarding adequate antimicrobial therapy. © 2012 Elsevier España, S.L. All rights reserved.3228792Sanders, Jr.W.E., Sanders, C.C., Enterobacter spp.: Pathogens poised to flourish at the turn of the century (1997) Clin Microbiol Rev, 10, pp. 220-241Ho, P.L., Shek, R.H., Chow, K.H., Lai, W.M., Detection and characterization of extended-spectrum beta-lactamases among bloodstream isolates of Enterobacter spp. in Hong Kong, 2000-2002 (2005) J Antimicrob Chemother, 55, pp. 326-332Thomson, K.S., Extended-spectrum-β-lactamase, AmpC, and carbapenemase issues (2010) J Clin Microbiol, 48, pp. 1019-1025Rodríguez-Baño, J., Picón, E., Gijón, P., Hernández, J.R., Cisneros, J.M., Peña, C., Risk factors and prognosis of nosocomial bloodstream infections caused by extended-spectrum-beta-lactamase-producing Escherichia coli (2010) J Clin Microbiol, 48, pp. 1726-1731Schwaber, M.J., Carmeli, Y., Mortality and delay in effective therapy associated with extended-spectrum beta-lactamase production in Enterobacteriaceae bacteraemia: A systematic review and meta-analysis (2007) J Antimicrob Chemother, 60, pp. 913-920Tumbarello, M., Spanu, T., Di Bidino, R., Marchetti, M., Ruggeri, M., Trecarichi, E.M., Costs of bloodstream infections caused by Escherichia coli and influence of extended-spectrum-beta-lactamase production and inadequate initial antibiotic therapy (2010) Antimicrob Agents Chemother, 54, pp. 4085-4091Cheong, H.S., Ko, K.S., Kang, C.I., Chung, D.R., Peck, K.R., Song, J.H., Clinical significance of infections caused by extended-spectrum b-lactamase-producing Enterobacteriaceae Blood isolates with inducible AmpC b-lactamase (2012) Microbial Drug Resist, 18, pp. 446-452Towne, T.G., Lewis, J.S., Herrera, M., Wickes, B., Jorgensen, J.H., Detection of SHVtype extended-spectrum beta-lactamase in Enterobacter isolates (2010) J Clin Microbiol, 48, pp. 298-299(2011) Susceptibility TestingTwenty-First Informational Supplement M100-S21, , Clinical and Laboratory Standards Institute. 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Assoc Physicians India, 51, pp. 669-672Marchaim, D., Gottesman, T., Schwartz, O., Korem, M., Maor, Y., Rahav, G., National multicenter study of predictors and outcomes of bacteremia upon hospital admission caused by Enterobacteriaceae producing extended-spectrum beta-lactamases (2010) Antimicrob Agents Chemother, 54, pp. 5099-5104Pai, H., Hong, J.Y., Byeon, J.H., Kim, Y.K., Lee, H.J., High prevalence of extended-spectrum beta-lactamase-producing strains among blood isolates of Enterobacter spp collected in a tertiary hospital during an 8-year period and their antimicrobial susceptibility patterns (2004) Antimicrob Agents Chemother, 48, pp. 3159-3161García-Hernández, A., García-Vázquez, E., Gómez-Gómez, J., Canteras, M., Hernandez-Torres, A., Ruiz-Gomes, J., Predictor factors of ESBL versus non-ESBL Escherichia coli bacteraemia and influence of resistance on the mortality of the patients (2010) Med Clin (Barc), 136, pp. 56-60Marcos, M., Iñurrieta, A., Soriano, A., Martínez, J.A., Almela, M., Marco, F., Effect of antimicrobial therapy on mortality in 377 episodes of Enterobacter spp bacteraemia (2008) J Antimicrob Chemother, 62, pp. 397-403Bonnet, R., Dutour, C., Sampaio, J.L.M., Chanal, C., Sirot, D., Labia, R., Novel cefotaximase (CTX-M-16) with increased catalytic efficiency due to substitution Asp-240→Gly (2001) Antimicrob Agents Chemother, 45, pp. 2269-227