Il Numero 0 del primo giornale online della Cattedra Unesco in \u201cAntropologia della Salute. Biosfera e Sistemi di Cura\u201d

Il presente contributo intende raccontare l\u2019origine e lo sviluppo di un progetto di promozione della diversit\ue0 culturale, di dialogo interculturale e di accesso alla cultura (Decisione UE 864/2017, Art. 2.1.a). Un progetto che mira a fortificare, direttamente e indirettamente, processi di pace (Decisione UE 864/2017, Art. 2.2.k), facilitando la creazione di contatti tra i gruppi etnici e religiosi, rafforzando l\u2019identit\ue0 culturale e l\u2019apertura verso il prossimo, eliminando stereotipi spesso causa di tensioni sociali, etniche o religiose, e garantendo a tutti il diritto di accedere alla cultura (Decisione UE 864/2017, Art. 2.2.d), in accordo con le Linee Guida della Cooperazione Italiana su Patrimonio Culturale e Sviluppo

Generation of eX vivo-vascularized Muscle Engineered Tissue (X-MET)

The object of this study was to develop an in vitro bioengineered three-dimensional vascularized skeletal muscle tissue, named eX-vivo Muscle Engineered Tissue (X-MET). This new tissue contains cells that exhibit the characteristics of differentiated myotubes, with organized contractile machinery, undifferentiated cells, and vascular cells capable of forming "vessel-like" networks. X-MET showed biomechanical properties comparable with that of adult skeletal muscles; thus it more closely mimics the cellular complexity typical of in vivo muscle tissue than myogenic cells cultured in standard monolayer conditions. Transplanted X-MET was able to mimic the activity of the excided EDL muscle, restoring the functionality of the damaged muscle. Our results suggest that X-MET is an ideal in vitro 3D muscle model that can be employed to repair muscle defects in vivo and to perform in vitro studies, limiting the use of live animals