A probabilistic approach to quantum mechanics based on tomograms

It is usually believed that a picture of Quantum Mechanics in terms of true probabilities cannot be given due to the uncertainty relations. Here we discuss a tomographic approach to quantum states that leads to a probability representation of quantum states. This can be regarded as a classical-like formulation of quantum mechanics which avoids the counterintuitive concepts of wave function and density operator. The relevant concepts of quantum mechanics are then reconsidered and the epistemological implications of such approach discussed

Progress and challenges in the vaccine-based treatment of head and neck cancers

Head and neck (HN) cancer represents one of the most challenging diseases because the mortality remains high despite advances in early diagnosis and treatment. Although vaccine-based approaches for the treatment of advanced squamous cell carcinoma of the head and neck have achieved limited clinical success, advances in cancer immunology provide a strong foundation and powerful new tools to guide current attempts to develop effective cancer vaccines. This article reviews what has to be rather what has been done in the field for the development of future vaccines in HN tumours

The intonation and pragmatics of Greek wh-questions

We experimentally tested three hypotheses regarding the pragmatics of two tunes (one high-ending, one flat-ending) used with Greek wh-questions: (a) the high-ending tune is associated with information-seeking questions, while the flat-ending tune is also appropriate when wh-questions are not information-seeking in which case their function can instead be akin to that of a statement; (b) the high-ending tune is more polite, and (c) more appropriate for contexts leading to information-seeking questions. The wh-questions used as experimental stimuli were elicited from four speakers in contexts likely to lead to either information-seeking or non-information-seeking uses. The speakers produced distinct tunes in response to the contexts; acoustic analysis indicates these are best analysed as L*+H L-!H% (rising), and L+H* L-L% (flat). In a perception experiment where participants heard the questions out of context, they chose answers providing information significantly more frequently after high-ending than flat-ending questions, confirming hypothesis (a). In a second experiment testing hypotheses (b) and (c), participants evaluated wh-questions for appropriateness and politeness in information- and non-information-seeking contexts. High-ending questions were rated more appropriate in information-seeking contexts, and more polite independently of context relative to their flat-ending counterparts. Finally, two follow-up experiments showed that the interpretation of the two tunes was not affected by voice characteristics of individual speakers, and confirmed a participant preference for the high-ending tune. Overall, the results support our hypotheses and lead to a compositional analysis of the meaning of the two tunes, while also showing that intonational meaning is determined by both tune and pragmatic context