Higher simple structure sets of lens spaces with the fundamental group of order 2K2^K

Extending work of many authors we calculate the higher simple structure sets of lens spaces in the sense of surgery theory in the case when the fundamental group has order a power of $2$. As a corollary we also obtain a calculation of the simple structure set of the products of lens spaces and spheres of dimension grater or equal to $3$ in this case.Comment: 20 page

Myosin-Like Proteins in S. cerevisiae: Multifunctional, Structural Components of the Nuclear Envelope

The nuclear envelope (NE) separates the genetic material from the rest of the cell, delimits and defines the nucleus, organizes the intranuclear architecture and serves as a regulator for multiple nuclear processes. In all eukaryotes, filamentous coiled-coil proteins are associated with the intranuclear surface of the NE and are integral to proper nuclear function. One such protein, called Tpr in vertebrates, attaches to the NPC and appears to form the nuclear basket structure, is conserved throughout all eukaryotes. The two yeast homologs of Tpr are termed Mlp1p and Mlp2p. The Mlp proteins also attach to the nuclear face of the NPC and form a layer underneath the NE. For my thesis work I examined the structure and function of the Mlp proteins. A proteomic study of Mlp associated complexes revealed that the Mlp proteins interact predominantly with components of the NPC, the mRNA transport and processing machinery, and the spindle pole body (SPB; the yeast microtubule organizing center). Structural and microscopic analyses show that the Mlp proteins may form the nuclear basket in yeast, as well as interconnect NPCs into a network. Finally, a detailed functional study demonstrated that Mlp2p binds directly to the SPB and promotes the incorporation of components into the core structure of the SPB. The data presented in this thesis supports a model in which the Mlp proteins integrate the NPCs and the SPBs into a continuous structure at the nuclear periphery. This network supports the stability of the NE and, by its interaction with soluble factors, directly influences nuclear functions like SPB maintenance and mRNP metabolism

Locating and Identifying Codes in Circulant Networks

A set S of vertices of a graph G is a dominating set of G if every vertex u of G is either in S or it has a neighbour in S. In other words, S is dominating if the sets S\cap N[u] where u \in V(G) and N[u] denotes the closed neighbourhood of u in G, are all nonempty. A set S \subseteq V(G) is called a locating code in G, if the sets S \cap N[u] where u \in V(G) \setminus S are all nonempty and distinct. A set S \subseteq V(G) is called an identifying code in G, if the sets S\cap N[u] where u\in V(G) are all nonempty and distinct. We study locating and identifying codes in the circulant networks C_n(1,3). For an integer n>6, the graph C_n(1,3) has vertex set Z_n and edges xy where x,y \in Z_n and |x-y| \in {1,3}. We prove that a smallest locating code in C_n(1,3) has size \lceil n/3 \rceil + c, where c \in {0,1}, and a smallest identifying code in C_n(1,3) has size \lceil 4n/11 \rceil + c', where c' \in {0,1}

Independence and Domination in Path Graphs of Trees

The problems of determining the maximum cardinality of an independent set of vertices and the minimum cardinality of a maximal independent set of vertices of a graph are known to be NP-complete. We provide efficient algorithms for finding these values for path graphs of trees

Independence Number in Path Graphs

In the paper we present results, which allow us to compute the independence numbers of $P_2$-path graphs and $P_3$-path graphs of special graphs. As $P_2(G)$ and $P_3(G)$ are subgraphs of iterated line graphs $L^2(G)$ and $L^3(G)$, respectively, we compare our results with the independence numbers of corresponding iterated line graphs

Comparative study of osteogenic activity of multilayers made of synthetic and biogenic polyelectrolytes

Polyelectrolyte multilayer (PEM) coatings on biomaterials are applied to tailor adhesion, growth, and function of cells on biomedical implants. Here, biogenic and synthetic polyelectrolytes (PEL) are used for layer-by-layer assembly to study the osteogenic activity of PEM with human osteosarcoma MG-63 cells in a comparative manner. Formation of PEM is achieved with biogenic PEL fibrinogen (FBG) and poly-l-lysine (PLL) as well as biotinylated chondroitin sulfate (BCS) and avidin (AVI), while poly(allylamine hydrochloride) (PAH) and polystyrene sulfonate (PSS) represent a fully synthetic PEM used as a reference system here. Surface plasmon resonance measurements show highest layer mass for FBG/PLL and similar for PSS/PAH and BCS/AVI systems, while water contact angle and zeta potential measurements indicate larger differences for PSS/PAH and FBG/PLL but not for BCS/AVI multilayers. All PEM systems support cell adhesion and growth and promote osteogenic differentiation as well. However, FBG/PLL layers are superior regarding MG-63 cell adhesion during short-term culture, while the BCS/AVI system increases alkaline phosphatase activity in long-term culture. Particularly, a multilayer system based on affinity interaction like BCS/AVI may be useful for controlled presentation of biotinylated growth factors to promote growth and differentiation of cells for biomedical applications

Gruppenstrukturen in Rockmusikgruppen

ln dem Reader von Bontinck (1974) weist Blaukopf in seinem Beitrag darauf hin, daß u. a. das Spielen in Gruppen eine neue Form musikalischer Aktivitäten von Jugendlichen sei. Somit ist die Gruppe, in der Rockmusik gespielt wird, eine wichtige Bezugsgruppe; Intragruppenbeziehungen stellen daher einen bedeutsamen Faktor dar. Dies wird bei einer jugendsoziologisch bzw. pädagogisch orientierten Forschung eher übersehen: So nennt z. B. Lewis (1979) in seiner Bibliographie keine Abhandlung über dieses Thema. […] Insofern kann eine Analyse der Gruppenstrukturen und -prozesse von Rockmusikgruppen auf sozialpsychologische Theorien der Kleingruppenforschung zurückgreifen. Im Vordergrund stehen hierbei problematische Sachverhalte der Gruppenkohäsion, der Konformität, der Aufgaben- bzw. Mitgliederorientierung (Zielvorstellungen), des Status oder der Gruppenleistung. (DIPF/Orig.

The importance of cognitive and social skills for the duration of unemployment

This paper studies how cognitive and social skills in childhood are related to the duration of unemployment in adolescence and early adulthood. I estimate a flexible proportional hazard rate model for the probability of making a transition from unemployment to employment during an individual’s first unemployment spell. The analysis is based on British cohort data from the National Child Development Study. Results show that higher cognitive and social skills at the age of 7 are associated with an increased probability of finding employment, even when controlling for educational attainment. For men, these effects are mostly driven by individuals with low social skills. The results are robust to controlling for family background, parenting activities and school characteristics