14 research outputs found
Effectiveness of ophthalmic solution preservatives: a comparison of latanoprost with 0.02% benzalkonium chloride and travoprost with the sofZia preservative system
- Author
- AL Hennessy
- C Charnock
- Cherie Lovelace
- CJ Cruz-Colon
- CW Eifrig
- DA Godfrey
- European Directorate for the Quality of Medicines
- European Medicines Agency
- EW Leung
- F Schaefer
- Gerard Ryan
- IP Kaur
- JC Henry
- JL Stone
- Joel M Fain
- JR Townley
- Karl M Gelotte
- L Keay
- MB Horsley
- N Nagai
- O Geyer
- OD Schein
- P Furrer
- RA Lewis
- RJ Noecker
- S Kotak
- S Waheed
- SD McPherson Jr
- T Bourcier
- The United States Pharmacopeia Convention
- TM Aaberg Jr
- Xalatan (latanoprost ophthalmic solution)
- Ykuji Nippo Ltd
- Publication venue
- BioMed Central
- Publication date
- 01/01/2011
- Field of study
<p>Abstract</p> <p>Background</p> <p>Although in vitro and in vivo laboratory studies have suggested that benzalkonium chloride (BAK) in topical ophthalmic solutions may be detrimental to corneal epithelial cells, multiple short- and long-term clinical studies have provided evidence supporting the safety of BAK. Despite the conflicting evidence, BAK is the most commonly used preservative in ophthalmic products largely due to its proven antimicrobial efficacy. This study was designed to characterize the antimicrobial performance of two commonly used topical ocular hypotensive agents that employ different preservative systems: latanoprost 0.005% with 0.02% BAK and travoprost 0.004% with sofZia, a proprietary ionic buffer system.</p> <p>Methods</p> <p>Each product was tested for antimicrobial effectiveness by <it>European Pharmacopoeia </it>A (EP-A) standards, the most stringent standards of the three major compendia, which specify two early sampling time points (6 and 24 hours) not required by the <it>United States Pharmacopeia </it>or <it>Japanese Pharmacopoeia</it>. Aliquots were inoculated with between 10<sup>5 </sup>and 10<sup>6 </sup>colony-forming units of the test organisms: <it>Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Candida albicans </it>and <it>Aspergillus brasiliensis</it>. Sampling and enumeration were conducted at protocol-defined time points through 28 days.</p> <p>Results</p> <p>BAK-containing latanoprost met EP-A criteria by immediately reducing all bacterial challenge organisms to the test sensitivity and fungal challenges within the first six hours while the preservative activity of travoprost with sofZia did not. Complete bacterial reduction by travoprost with sofZia was not shown until seven days into the test, and fungal reduction never exceeded the requisite 2 logs during the 28-day test. Travoprost with sofZia also did not meet EP-B criteria due to its limited effectiveness against <it>Staphylococcus aureus</it>. Both products satisfied United States and Japanese pharmacopoeial criteria.</p> <p>Conclusions</p> <p>Latanoprost with 0.02% BAK exhibited more effective microbial protection than travoprost with sofZia using rates of microbial reduction, time to no recovery for all challenges and evaluation against EP-A criteria as measures. The rapid and complete reduction of all microbial challenges demonstrates that antimicrobial activity of latanoprost with 0.02% BAK exceeds that of travoprost with sofZia preservative system in these products and provides a more protective environment in the event of contamination and subsequent exposure to microorganisms during use.</p
Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
- Abdinov O
- Abi B
- Abolins M
- Abramowicz H
- Abreu H
- Acerbi E
- Acharya BS
- Ackers M
- Adams DL
- Addy TN
- Adelman J
- Aderholz M
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Aharrouche M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akdogan T
- Akesson TPA
- Akimoto G
- Akimov AV
- Alam MA
- Alam MS
- Albrand S
- Aleksa M
- Aleksandrov IN
- Aleppo M
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Aliyev M
- Allport PP
- Allwood-Spiers SE
- Almenar CC
- Almond J
- Aloisio A
- Alon R
- Alonso A
- Alonso J
- Alviggi MG
- Amako K
- Amaral P
- Amelung C
- Ammosov VV
- Amorim A
- Amoros G
- Amram N
- Anastopoulos C
- Andari N
- Andeen T
- Anders CF
- Anderson KJ
- Andreazza A
- Andrei V
- Andrieux M-L
- Anduaga XS
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- Armbruster AJ
- Arms KE
- Armstrong SR
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- Yilmaz M
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- Zajacova Z
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- Zarzhitsky P
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- Zenin AV
- Zenin O
- Zenis T
- Zenonos Z
- Zenz S
- Zerwas D
- Zhan Z
- Zhang D
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- Zhang X
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- Zhao Z
- Zhemchugov A
- Zheng S
- Zhong J
- Zhou B
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- Zhu H
- Zhu Y
- Zhuang X
- Zhuravlov V
- Zieminska D
- Zilka B
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Ziolkowski M
- Zitoun R
- Zivkovic L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- Zolnierowski Y
- Zsenei A
- zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 31/12/2010
- Field of study
The inclusive and dijet production cross-sections have been measured for jets
containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass
energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The
measurements use data corresponding to an integrated luminosity of 34 pb^-1.
The b-jets are identified using either a lifetime-based method, where secondary
decay vertices of b-hadrons in jets are reconstructed using information from
the tracking detectors, or a muon-based method where the presence of a muon is
used to identify semileptonic decays of b-hadrons inside jets. The inclusive
b-jet cross-section is measured as a function of transverse momentum in the
range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet
cross-section is measured as a function of the dijet invariant mass in the
range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets
and the angular variable chi in two dijet mass regions. The results are
compared with next-to-leading-order QCD predictions. Good agreement is observed
between the measured cross-sections and the predictions obtained using POWHEG +
Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet
cross-section. However, it does not reproduce the measured inclusive
cross-section well, particularly for central b-jets with large transverse
momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final
version published in European Physical Journal
Sarcopenia as a predictor of hospitalization among older people: a systematic review and meta-analysis
- Author
- A Stang
- A Zembron-Lacny
- AJ Cruz-Jentoft
- AJ Cruz-Jentoft
- AJ Cruz-Jentoft
- AM Martone
- C Beaudart
- CJ Padilla Colon
- Conghua Wang
- CR Gale
- D Chalhoub
- D Legrand
- D Moher
- D Scott
- D Scott
- E Marty
- E Marzetti
- E Marzetti
- F Landi
- G Bano
- H Matsumoto
- HA Bischoff-Ferrari
- I Bosaeus
- IH Rosenberg
- J Woo
- KSF Khow
- KV Chang
- L Bianchi
- L Lera
- LK Chen
- M Hars
- M Yang
- MA Clynes
- N Fuggle
- P Liu
- PM Cawthon
- PM Cawthon
- Qingli Dou
- R Yu
- S Gariballa
- SY Wang
- T Henwood
- Wenwu Zhang
- Wuyuan Tao
- Xiaoming Zhang
- Yunzhi Yang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Anti-influenza hyperimmune intravenous immunoglobulin for adults with influenza A or B infection (FLU-IVIG): a double-blind, randomised, placebo-controlled trial
- Author
- Aagaard B
- Abela C
- Alonso H
- Anagnostou O
- Arters KA
- Avihingsanon A
- Babiker AG
- Baxter J
- Beigel JH
- Butts J
- Carbonneau JY
- Carey D
- Clark LA
- Coburn P
- Collaco-Moraes Y
- Colon RJ
- Conwell D
- Coyle EM
- Cursley A
- Davey RT
- DeConcini M
- Denning E
- Dewar R
- DuChene A
- Engen N
- Faber L
- Farrough MJ
- Fernández-Cruz E
- Finley E
- Fitzpatrick ME
- Flowers E
- Gambardella L
- Gardner EM
- Gioukari V
- Gordin F
- Harrison M
- Hillman LM
- Hoover M
- Hudson F
- Jackson B
- Jain MK
- Johnson SA
- Kan V
- Kessinger CJ
- Khurana S
- Krum E
- Kunisaki KM
- Lach LA
- Lane HC
- Lopez P
- Losso MH
- Lundgren J
- MacArthur RA
- Makohon L
- Markowitz N
- McConnell R
- Meger S
- Metcalf J
- Mkumba L
- Morris A
- Munroe D
- Nahra R
- Natarajan V
- Neaton JD
- Omotosho B
- Panos RJ
- Pastor E
- Pearson M
- Petersen T
- Peterson R
- Pett S
- Polenakovik HM
- Polizzotto MN
- Purvis C
- Pussadee K
- Quan K
- Rehman T
- Riska P
- Rizza SA
- Robson R
- Russell C
- Ruxrungtham K
- Salata RA
- Scott JA
- Shaughnessy M
- Smith K
- Solórzano C
- Sy A
- Sánchez A
- Tasi CM
- Temesgen Z
- Thompson G
- Touloumi G
- Ubolyam S
- Vock D
- Vysyaraju K
- Webb H
- Wentworth D
- Whitaker JA
- Wolfe CR
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/11/2019
- Field of study
Background: Since the 1918 influenza pandemic, non-randomised studies and small clinical trials have suggested that convalescent plasma or anti-influenza hyperimmune intravenous immunoglobulin (hIVIG) might have clinical benefit for patients with influenza infection, but definitive data do not exist. We aimed to evaluate the safety and efficacy of hIVIG in a randomised controlled trial. Methods: This randomised, double-blind, placebo-controlled trial was planned for 45 hospitals in Argentina, Australia, Denmark, Greece, Mexico, Spain, Thailand, UK, and the USA over five influenza seasons from 2013–14 to 2017–18. Adults (≥18 years of age) were admitted for hospital treatment with laboratory-confirmed influenza A or B infection and were randomly assigned (1:1) to receive standard care plus either a single 500-mL infusion of high-titre hIVIG (0·25 g/kg bodyweight, 24·75 g maximum; hIVIG group) or saline placebo (placebo group). Eligible patients had a National Early Warning score of 2 points or greater at the time of screening and their symptoms began no more than 7 days before randomisation. Pregnant and breastfeeding women were excluded, as well as any patients for whom the treatment would present a health risk. Separate randomisation schedules were generated for each participating clinical site using permuted block randomisation. Treatment assignments were obtained using a web-based application by the site pharmacist who then masked the solution for infusion. Patients and investigators were masked to study treatment. The primary endpoint was a six-category ordinal outcome of clinical status at day 7, ranging in severity from death to resumption of normal activities after discharge. The choice of day 7 was based on haemagglutination inhibition titres from a pilot study. It was analysed with a proportional odds model, using all six categories to estimate a common odds ratio (OR). An OR greater than 1 indicated that, for a given category, patients in the hIVIG group were more likely to be in a better category than those in the placebo group. Prespecified primary analyses for safety and efficacy were based on patients who received an infusion and for whom eligibility could be confirmed. This trial is registered with ClinicalTrials.gov, NCT02287467. Findings: 313 patients were enrolled in 34 sites between Dec 11, 2014, and May 28, 2018. We also used data from 16 patients enrolled at seven of the 34 sites during the pilot study between Jan 15, 2014, and April 10, 2014. 168 patients were randomly assigned to the hIVIG group and 161 to the placebo group. 21 patients were excluded (12 from the hIVIG group and 9 from the placebo group) because they did not receive an infusion or their eligibility could not be confirmed. Thus, 308 were included in the primary analysis. hIVIG treatment produced a robust rise in haemagglutination inhibition titres against influenza A and smaller rises in influenza B titres. Based on the proportional odds model, the OR on day 7 was 1·25 (95% CI 0·79–1·97; p=0·33). In subgroup analyses for the primary outcome, the OR in patients with influenza A was 0·94 (0·55–1·59) and was 3·19 (1·21–8·42) for those with influenza B (interaction p=0·023). Through 28 days of follow-up, 47 (30%) of 156 patients in the hIVIG group and in 45 (30%) of 152 patients in the placebo group had the composite safety outcome of death, a serious adverse event, or a grade 3 or 4 adverse event (hazard ratio [HR] 1·06, 95% CI 0·70–1·60; p=0·79). Six (4%) patients in the hIVIG group and five (3%) in the placebo group died, but these deaths were not necessarily related to treatment. Interpretation: When administered alongside standard care (most commonly oseltamivir), hIVIG was not superior to placebo for adults hospitalised with influenza infection. By contrast with our prespecified subgroup hypothesis that hIVIG would result in more favourable responses in patients with influenza A than B, we found the opposite effect. The clinical benefit of hIVIG for patients with influenza B is supported by antibody affinity analyses, but confirmation is warranted. Funding: NIAID and NIH. Partial support was provided by the Medical Research Council (MRC_UU_12023/23) and the Danish National Research Foundation
Charged-particle multiplicities in pp interactions at root s=900 GeV measured with the ATLAS detector at the LHC ATLAS Collaboration
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
- Abdinov O
- Abi B
- Abolins M
- Abramowicz H
- Abreu H
- Acerbi E
- Acharya BS
- Ackers M
- Adams DL
- Addy TN
- Adelman J
- Aderholz M
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Aharrouche M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akdogan T
- Akimoto G
- Akimov AV
- Alam MA
- Alam MS
- Albrand S
- Aleksa M
- Aleksandrov IN
- Aleppo M
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Aliyev M
- Allport PP
- Allwood-Spiers SE
- Almond J
- Aloisio A
- Alon R
- Alonso A
- Alonso J
- Alviggi MG
- Amako K
- Amaral P
- Amelung C
- Ammosov VV
- Amorim A
- Amorós G
- Amram N
- Anastopoulos C
- Andeen T
- Anders CF
- Anderson KJ
- Andreazza A
- Andrei V
- Andrieux M
- Anduaga XS
- Angerami A
- Anghinolfi F
- Anjos N
- Annovi A
- Antonaki A
- Antonelli M
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- Oakham FG
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- Ocariz J
- Ochi A
- Oda S
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- Odier J
- Odino GA
- Ogren H
- Oh A
- Oh SH
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- Ohshima T
- Ohshita H
- Ohska TK
- Ohsugi T
- Okada S
- Okawa H
- Okumura Y
- Okuyama T
- Olcese M
- Olchevski AG
- Oliveira Damazio D
- Oliveira M
- Oliver Garcia E
- Olivito D
- Olszewski A
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- Omachi C
- Onofre A
- Onyisi PUE
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- Ordonez G
- Oreglia MJ
- Orellana F
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- Orlov I
- Oropeza Barrera C
- Orr RS
- Ortega EO
- Osculati B
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- Ottersbach JP
- Ouchrif M
- Ould-Saada F
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- Owen M
- Owen S
- Oyarzun A
- Ozcan VE
- Åkesson TPA
- Åsman B
- Øye OK
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2010
- Field of study
Measurement of the inclusive isolated prompt photon cross section in pp collisions at √s=7 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
- Abdinov O
- Abi B
- Abolins M
- Abramowicz H
- Abreu H
- Acerbi E
- Acharya BS
- Ackers M
- Adams DL
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- Adelman J
- Aderholz M
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Aharrouche M
- Ahlen SP
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- Aielli G
- Akdogan T
- Akesson TPA
- Akimoto G
- Akimov AV
- Alam MA
- Alam MS
- Albrand S
- Aleksa M
- Aleksandrov IN
- Aleppo M
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
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- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Aliyev M
- Allport PP
- Allwood-Spiers SE
- Almenar CC
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- Aloisio A
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- Amelung C
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- Anh TV
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- Antonaki A
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- Anulli F
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- Apolle R
- Arabidze G
- Aracena I
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- Arce ATH
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- Arfaoui S
- Arguin J-F
- Arik E
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- Armbruster AJ
- Arms KE
- Armstrong SR
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- Artamonov A
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- Arutinov D
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- Cheatham S
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- Chelkov GA
- Chen H
- Chen L
- Chen S
- Chen T
- Chen X
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- Zhemchugov A
- Zheng S
- Zhong J
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- Zhu CG
- Zhu H
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- Zhuang X
- Zhuravlov V
- Zieminska D
- Zilka B
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Ziolkowski M
- Zitoun R
- Zivkovic L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- Zolnierowski Y
- Zsenei A
- zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/12/2010
- Field of study
A measurement of the cross section for the inclusive production of isolated prompt photons in pp collisions at a center-of-mass energy [sqrt]s=7 TeV is presented. The measurement covers the pseudorapidity ranges |etaγ|<1.37 and 1.52≤|etaγ|<1.81 in the transverse energy range 15≤ETγ<100 GeV. The results are based on an integrated luminosity of 880 nb-1, collected with the ATLAS detector at the Large Hadron Collider. Photon candidates are identified by combining information from the calorimeters and from the inner tracker. Residual background in the selected sample is estimated from data based on the observed distribution of the transverse isolation energy in a narrow cone around the photon candidate. The results are compared to predictions from next-to-leading-order perturbative QCD calculations.United States. Dept. of EnergyNational Science Foundation (U.S.
Measurement of inclusive jet and dijet cross sections in proton-proton collisions at 7 TeV centre-of-mass energy with the ATLAS detector
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- Zimmermann S
- Ziolkowski M
- Zitoun R
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- Zmouchko VV
- Zobernig G
- Zoccoli A
- Zolnierowski Y
- Zsenei A
- zur Nedden M
- Zutshi V
- Publication venue
- Publication date
- 01/01/2011
- Field of study
Measurement of the inclusive isolated prompt photon cross section in pp collisions at root s=7 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
- Abdinov O
- Abi B
- Abolins M
- Abramowicz H
- Abreu H
- Acerbi E
- Acharya BS
- Ackers M
- Adams DL
- Addy TN
- Adelman J
- Aderholz M
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Aharrouche M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akdogan T
- Akesson TPA
- Akimoto G
- Akimov AV
- Alam MA
- Alam MS
- Albrand S
- Aleksa M
- Aleksandrov IN
- Aleppo M
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Aliyev M
- Allport PP
- Allwood-Spiers SE
- Almenar CC
- Almond J
- Aloisio A
- Alon R
- Alonso A
- Alonso J
- Alviggi MG
- Amako K
- Amaral P
- Amelung C
- Ammosov VV
- Amorim A
- Amoros G
- Amram N
- Anastopoulos C
- Andari N
- Andeen T
- Anders CF
- Anderson KJ
- Andreazza A
- Andrei V
- Andrieux ML
- Anduaga XS
- Angerami A
- Anghinolfi F
- Anh TV
- Anjos N
- Annovi A
- Antonaki A
- Antonelli M
- Antonelli S
- Antos J
- Anulli F
- Aoun S
- Apolle R
- Arabidze G
- Aracena I
- Arai Y
- Aranda CP
- Arce ATH
- Archambault JP
- Arfaoui S
- Arguin JF
- Arik E
- Arik M
- Armbruster AJ
- Arms KE
- Armstrong SR
- Arnaez O
- Arnault C
- Artamonov A
- Artoni G
- Arutinov D
- Asai S
- Asfandiyarov R
- Ask S
- Asman B
- Asquith L
- Assamagan K
- Astbury A
- Astvatsatourov A
- Atoian G
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- Auerbach B
- Auge E
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- Baccaglioni G
- Bacci C
- Bach AM
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- Bai Y
- Bailey DC
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- Publication venue
- Publication date
- 01/01/2011
- Field of study
Measurement of the W -> lv and Z/gamma* -> ll production cross sections in proton-proton collisions at root s=7 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
- Abdinov O
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- Abreu H
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- Publication venue
- Publication date
- 01/01/2010
- Field of study
First measurements of the W → ℓν and Z/γ * → ℓℓ (ℓ = e, μ) production cross sections in proton-proton collisions at √ s = 7TeV are presented using data recorded by the ATLAS experiment at the LHC. The results are based on 2250 W → ℓν and 179 Z/γ* → ℓℓ candidate events selected from a data set corresponding to an integrated luminosity of approximately 320 nb-1. The measured total W and Z/ γ*-boson production cross sections times the respective leptonic branching ratios for the combined electron and muon channels are σtotW · BR(W → ℓν) = 9.96 ± 0.23(stat) ± 0.50(syst) ± 1.10(lumi) nb and σtotZ/γ* · BR(Z/ γ* → ℓℓ) = 0.82 ± 0.06 (stat) ± 0.05 (syst) ± 0.09 (lumi) nb (within the invariant mass window 66 < mℓℓ < 116 GeV). The W/Z cross-section ratio is measured to be 11.7 ± 0.9(stat) ± 0.4(syst). In addition, measurements of the W+ and W- production cross sections and of the lepton charge asymmetry are reported. Theoretical predictions based on NNLO QCD calculations are found to agree with the measurements
Performance of the ATLAS Detector using First Collision Data
- Author
- Aad G
- Abat E
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
- Abdinov O
- Abi B
- Abolins M
- Abramowicz H
- Abreu H
- Acerbi E
- Acharya BS
- Ackers M
- Adams DL
- Addy TN
- Adelman J
- Aderholz M
- Adomeit S
- Adorisio C
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Aharrouche M
- Ahlen SP
- Ahles F
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- Aielli G
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- Akesson PF
- Akesson TPA
- Akimoto G
- Akimov AV
- Aktas A
- Alam MA
- Alam MS
- Albrand S
- Aleksa M
- Aleksandrov IN
- Aleppo M
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Aliyev M
- Allport PP
- Allwood-Spiers SE
- Almenar CC
- Almond J
- Aloisio A
- Alon R
- Alonso A
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- Alviggi MG
- Amako K
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- Ambrosini G
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- Ammosov VV
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- Amoros G
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- Anastopoulos C
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- Anders CF
- Anderson KJ
- Andreazza A
- Andrei V
- Andrieux M-L
- Anduaga XS
- Angerami A
- Anghinolfi F
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- Annovi A
- Antonaki A
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- Antos J
- Antunovic B
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- Arabidze G
- Aracena I
- Arai Y
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- Publication venue
- Springer
- Publication date
- 01/01/2010
- Field of study
More than half a million minimum-bias events of LHC collision data were
collected by the ATLAS experiment in December 2009 at centre-of-mass energies
of 0.9 TeV and 2.36 TeV. This paper reports on studies of the initial
performance of the ATLAS detector from these data. Comparisons between data and
Monte Carlo predictions are shown for distributions of several track- and
calorimeter-based quantities. The good performance of the ATLAS detector in
these first data gives confidence for successful running at higher energies