Algunhas propostas sobre as unidades, relacións e funcións sintácticas

[Resumo] Consciente da dificultade dos temas que se tratan neste traballo, tanto pola súa amplitude como polas controversias suscitadas no estudo da sintaxe moderna, pareceume adecuado tocar só algúns aspectos fundamentais que atinxen á problemática da fixación das unidades principais e os seus subtipos, así como á complexidade das relacións e funcións sintácticas que operan nesas unidades. O obxectivo non é, pois, elaborar un minitratado de sintaxe, aínda que considero que non está de máis identificar os tipos de relacións, de unidades e de funcións sintácticas con que imos traballar, como paso previo a calquera precisión.[Abstract] Being conscious of the difficulty regarding the topics which we deal with in this work, both for its wideness and for the controversies which when studying modern syntax, I thought convenient to study only a few basic aspects which affect the problem of defining the main units and its subtypes as well as the complexity of the syntactic relations and functions which work in these units. The aim is not, therefore, to elaborate a small volume on syntax, while I consider it is not completely out of the question to identify the syntactic relation types, units and functions which we are going to work, with as a step previous to any accuracy

History-based Self-Organizing Traffic Lights

Managing traffic in cities is nowadays a complex problem involving considerable physical and economical resources. Multi-agent Systems (MAS) consist of a set of distributed, usually co-operating, agents that act autonomously. The traffic in a city can be simulated by a MAS with different agents, cars and traffic lights, that interact to obtain an overall goal: to reduce average waiting times for the traffic users. In this paper, we describe an agent-based simulator to model traffic in cities.Using this simulator, we present a self-organizing solution to efficiently manage urban traffic. We compare our proposal with recent approaches, providing better results than classical and alternative self-organizing methods, with lower resources and investments

Voice Conversion Using K-Histograms and Residual Averaging

The main goal of a voice conversion system is to modify the voice of a source speaker, in order to be perceived as if it had been uttered by another specific speaker.   Many approaches found in the literature convert only the features related to the vocal tract of the speaker. Our proposal is to convert those characteristics of the vocal tract, and also to process the signal passing through the vocal chords. Thus, the goal of this work is to obtain better scores in the voice conversion results.Fil: Uriz, Alejandro José. Universidad Nacional de Mar del Plata. Facultad de Ingenieria. Departamento de Electronica. Laboratorio de Comunicaciones; ArgentinaFil: Pablo D. Agüero. Consejo Nacional de Invest.cientif.y Tecnicas. Centro Cientifico Tecnol.conicet - Mar del Plata;Fil: Castiñeira Moreira; Jorge. Universidad Nacional de Mar del Plata. Facultad de Ingenieria. Departamento de Electronica. Laboratorio de Comunicaciones;Fil: Tulli, J. C.. Universidad Nacional de Mar del Plata. Facultad de Ingenieria. Departamento de Electronica. Laboratorio de Comunicaciones; ArgentinaFil: González, Esteban Lucio. Consejo Nacional de Invest.cientif.y Tecnicas. Centro Cientifico Tecnol.conicet - Mar del Plata; ArgentinaFil: Bonafonte, A.. Universidad Nacional de Mar del Plata. Facultad de Ingenieria. Departamento de Electronica. Laboratorio de Comunicaciones; Argentin

An Encryption and Error-Control Coding scheme based on Non binary LDPC codes

In this paper we present a combined error-control coding and encryption scheme that provides to a given system with both high levels of reliability of the transmission and security. These two aims are usually present in wireless data transmission systems. The scheme is based on efficient Non Binary Low Density Parity Check codes which were selected for this design because they outer perform their binary counterparts. By means of a set of operations over the parity check matrix of the code, encryption capabilities are added to the scheme, without producing any degradation in the corresponding Bit Error Rate performance, as usually happens when encryption and error control coding are applied separately.Sociedad Argentina de Informática e Investigación Operativ

Subwavelength slit acoustic metamaterial barrier

[EN] Reduction of noise in the transmission path is a very important environmental problem. The standard method to reduce this noise level is the use of acoustic barriers. In this paper, an acoustic metamaterial based on sound transmission through subwavelength slits, is tailored to be used as an acoustic barrier. This system consists of two rows of periodic repetition of vertical rigid pickets separated by a slit of subwavelength width, embedded in air. Here, both the experimental and the numerical analyses are presented. These analyses have facilitated the identification of the parameters that affect the insertion loss performance. The results demonstrated that the proposed barrier can be tuned to mitigate a band noise in a mechanical plant for buildings where openings for air flow are required as well as industrial noise, without excessive barrier thickness.This work was financially supported by the Spanish Ministry of Science and Innovation through project MAT2010-16879.Rubio Michavila, C.; Candelas Valiente, P.; Belmar Ibáñez, F.; Gómez Lozano, V.; Uris Martínez, A. (2015). Subwavelength slit acoustic metamaterial barrier. Journal of Physics D: Applied Physics. 48(39):1-9. https://doi.org/10.1088/0022-3727/48/39/395501S19483

Measurement of the 240Pu(n,f) cross-section at the CERN n-TOF facility : First results from experimental area II (EAR-2)

The accurate knowledge of the neutron-induced fission cross-sections of actinides and other isotopes involved in the nuclear fuel cycle is essential for the design of advanced nuclear systems, such as Generation-IV nuclear reactors. Such experimental data can also provide the necessary feedback for the adjustment of nuclear model parameters used in the evaluation process, resulting in the further development of nuclear fission models. In the present work, the 240Pu(n,f) cross-section was measured at CERN's n-TOF facility relative to the well-known 235U(n,f) cross section, over a wide range of neutron energies, from meV to almost MeV, using the time-of-flight technique and a set-up based on Micromegas detectors. This measurement was the first experiment to be performed at n-TOF's new experimental area (EAR-2), which offers a significantly higher neutron flux compared to the already existing experimental area (EAR-1). Preliminary results as well as the experimental procedure, including a description of the facility and the data handling and analysis, are presented

Role of VHL, HIF1A and SDH on the expression of miR-210: Implications for tumoral pseudo-hypoxic fate.

The hypoxia-inducible factor 1α (HIF-1α) and its microRNA target, miR-210, are candidate tumor-drivers of metabolic reprogramming in cancer. Neuroendocrine neoplasms such as paragangliomas (PGLs) are particularly appealing for understanding the cancer metabolic adjustments because of their associations with deregulations of metabolic enzymes, such as succinate dehydrogenase (SDH), and the von Hippel Lindau (VHL) gene involved in HIF-1α stabilization. However, the role of miR-210 in the pathogenesis of SDH-related tumors remains an unmet challenge. Herein is described an in vivo genetic analysis of the role of VHL, HIF1A and SDH on miR-210 by using knockout murine models, siRNA gene silencing, and analyses of human tumors. HIF-1α knockout abolished hypoxia-induced miR-210 expression in vivo but did not alter its constitutive expression in paraganglia. Normoxic miR-210 levels substantially increased by complete, but not partial, VHL silencing in paraganglia of knockout VHL-mice and by over-expression of p76del-mutated pVHL. Similarly, VHL-mutated PGLs, not those with decreased VHL-gene/mRNA dosage, over-expressed miR-210 and accumulate HIF-1α in most tumor cells. Ablation of SDH activity in SDHD-null cell lines or reduction of the SDHD or SDHB protein levels elicited by siRNA-induced gene silencing did not induce miR-210 whereas the presence of SDH mutations in PGLs and tumor-derived cell lines was associated with mild increase of miR-210 and the presence of a heterogeneous, HIF-1α-positive and HIF-1α-negative, tumor cell population. Thus, activation of HIF-1α is likely an early event in VHL-defective PGLs directly linked to VHL mutations, but it is a late event favored but not directly triggered by SDHx mutations. This combined analysis provides insights into the mechanisms of HIF-1α/miR-210 regulation in normal and tumor tissues potentially useful for understanding the pathogenesis of cancer and other diseases sharing similar underpinnings

Codevelopment and citizenship: the nexus between policies on local migrant incorporation and migrant transnational practices in Spain

Over the last decade both national and local actors in Spain have picked up on international trends encouraging a policy framework of migration and development. Policies of codevelopment are tied in with issues of migration management in the sense of linking current and future migration flows with processes of development in the country of origin. However, this article demonstrates how codevelopment policies and initiatives of local governments in Catalonia also relate to migrants’ local process of incorporation in their country of residence. In so doing the article seeks to bridge and contribute to studies of migration and development as well as issues of national and local citizenship and migrant incorporation. Importantly, the article highlights the role of receiving country local governments in the nexus between migrant transnational practices and processes of incorporation

Autoantibodies against MHC class I polypeptide-related sequence A are associated with increased risk of concomitant autoimmune diseases in celiac patients

Background: Overexpression of autologous proteins can lead to the formation of autoantibodies and autoimmune diseases. MHC class I polypeptide-related sequence A (MICA) is highly expressed in the enterocytes of patients with celiac disease, which arises in response to gluten. The aim of this study was to investigate anti-MICA antibody formation in patients with celiac disease and its association with other autoimmune processes. Methods: We tested serum samples from 383 patients with celiac disease, obtained before they took up a gluten-free diet, 428 patients with diverse autoimmune diseases, and 200 controls for anti-MICA antibodies. All samples were also tested for anti-endomysium and anti-transglutaminase antibodies. Results: Antibodies against MICA were detected in samples from 41.7% of patients with celiac disease but in only 3.5% of those from controls (P <0.0001) and 8.2% from patients with autoimmune disease (P <0.0001). These antibodies disappeared after the instauration of a gluten-free diet. Anti-MICA antibodies were significantly prevalent in younger patients (P <0.01). Fifty-eight patients with celiac disease (15.1%) presented a concomitant autoimmune disease. Anti-MICA-positive patients had a higher risk of autoimmune disease than MICA antibody-negative patients (P <0.0001; odds ratio = 6.11). The risk was even higher when we also controlled for age (odds ratio = 11.69). Finally, we found that the associated risk of developing additional autoimmune diseases was 16 and 10 times as high in pediatric patients and adults with anti-MICA, respectively, as in those without. Conclusions: The development of anti-MICA antibodies could be related to a gluten-containing diet, and seems to be involved in the development of autoimmune diseases in patients with celiac disease, especially younger ones

Effect of killer immunoglobulin-like receptors in the response to combined treatment in patients with chronic hepatitis C virus infection

Killer immunoglobulin-like receptors (KIRs) are related to the activation and inhibition of NK cells and may play an important role in the innate response against infection with viruses such as hepatitis C virus (HCV). We examined whether the different combinations of KIRs with their HLA class I ligands influenced the response to combined treatment (pegylated alpha interferon and ribavirin) of patients infected by HCV. A total of 186 consecutive patients diagnosed with chronic HCV infection were analyzed. Seventy-seven patients exhibited HCV RNA levels at 6 months posttreatment and were called nonresponders (NR), while 109 cleared viral RNA and were named sustained viral responders (SVR). Patients were typed for HLA-B, HLA-Cw, KIR genes, and HCV genotype. In our study, the frequency of the KIR2DL2 allele was significantly increased in NR (P < 0.001; odds ratio [OR] = 1.95), as was the frequency of the KIR2DL2/KIR2DL2 genotype (P < 0.005; OR = 2.52). In contrast, the frequencies of the KIR2DL3 genotype (P < 0.001) and KIR2DL3/KIR2DL3 genotype (P < 0.05; OR = 0.54) were significantly increased in the SVR. Different combinations of KIR2DL2 and KIR2DL3 alleles with their ligands were analyzed. The frequency of the KIR2DL2/KIR2DL2-HLA-C1C2 genotype was significantly increased in the NR (P < 0.01; OR = 3.15). Additionally, we found a higher frequency of the KIR2DL3/KIR2DL3-HLA-C1C1 genotype in the SVR group (P < 0.05; OR = 0.33). These results were not affected by the HCV genotype. In conclusion, patients who carried the KIR2DL2/KIR2DL2-HLA-C1C2 genotype were less prone to respond to treatment. However, the KIR2DL3/KIR2DL3-HLA-C1C1 genotype clearly correlated with a satisfactory response to treatment, defined by the clearance of HCV RNA