Child-stripping in the Victorian City

During the nineteenth century, police, magistrates, reformers and the press noticed a rising tide of juvenile crime. Child-stripping, the crime of stealing young children's clothes by force or deception, was an activity of this type which caused alarm among contemporaries. As the century progressed, improved policing, urbanization and Irish migration, allied to growing social concern, caused more cases of child-stripping to be noticed. Accounts by Dickens, Mayhew and others characterized child-stripping as an activity indulged in by old women who were able to make money by victimizing the weakest strata of society. However, research in the British Library's digitized newspaper collections as well as in parliamentary papers conclusively demonstrates that child-stripping, far from being the domain of Dickensian crones, was actually perpetrated by older children, notably girls, against children even younger than themselves. Despite widespread revulsion, which at times approached a ‘moral panic’ prompted by the nature of the crime, progressive attitudes largely prevailed with most child-stripping children being sent to reformatories or industrial schools in the hope of reforming their behaviour. This article thus conforms with Foucauldian notions of the switch from physical to mental punishments and aligns with the Victorians’ invention of children as a category of humanity that could be saved

A contribution to the deterministic modelling of circadian rhythms in cell proliferation activity

This paper presents a deterministic continuous model of proliferative cell activity. The classical series of connected compartments is revisited along with a simple mathematical treatment of two hypotheses: constant transit times and harmonic Ts. Several examples are presented to support these ideas, both taken from previous literature and recent experiences with the fish Carassius auratus, developed at the Junta de Energía Nuclear, Madrid, Spain

Orthophosphate-P in the nutrient impacted River Taw and its catchment (SW England) between 1990 and 2013.

Excess dissolved phosphorus (as orthophosphate-P) contributes to reduced river water quality within Europe and elsewhere. This study reports results from analysis of a 23 year (1990-2013) water quality dataset for orthophosphate-P in the rural Taw catchment (SW England). Orthophosphate-P and river flow relationships and temporal variations in orthophosphate-P concentrations indicate the significant contribution of sewage (across the catchment) and industrial effluent (upper R. Taw) to orthophosphate-P concentrations (up to 96%), particularly during the low flow summer months when maximum algal growth occurs. In contrast, concentrations of orthophosphate-P from diffuse sources within the catchment were more important (>80%) at highest river flows. The results from a 3 end-member mixing model incorporating effluent, groundwater and diffuse orthophosphate-P source terms suggested that sewage and/or industrial effluent contributes ≥50% of the orthophosphate-P load for 27-48% of the time across the catchment. The Water Framework Directive (WFD) Phase 2 standards for reactive phosphorus, introduced in 2015, showed the R. Taw to be generally classified as Poor to Moderate Ecological Status, with a Good Status occurring more frequently in the tributary rivers. Failure to achieve Good Ecological Status occurred even though, since the early-2000s, riverine orthophosphate-P concentrations have decreased (although the mechanism(s) responsible for this could not be identified). For the first time it has been demonstrated that sewage and industrial effluent sources of alkalinity to the river can give erroneous boundary concentrations of orthophosphate-P for WFD Ecological Status classification, the extent of which is dependent on the proportion of effluent alkalinity present. This is likely to be a European - wide issue which should be examined in more detail

A long-term study of stable isotopes as tracers of processes governing water flow and quality in a lowland river basin: the upper Thames, UK

A long-term study of O, H and C stable isotopes has been undertaken on river waters across the 7000 km2 upper Thames lowland river basin in the southern UK. During the period, flow conditions ranged from drought to flood. A 10-year monthly record (2003–2012) of the main River Thames showed a maximum variation of 3‰ (δ18O) and 20‰ (δ2H), though inter-annual average values varied little around a mean of –6.5‰ (δ18O) and –44‰ (δ2H). The δ2H/δ18O slope of 5.3 suggested a degree of evaporative enrichment, consistent with derivation from local rainfall with a weighted mean of –7.2‰ (δ18O) and –48‰ (δ2H) for the period. A tendency towards isotopic depletion of the river with increasing flowrate was noted, but at very high flows (>100 m3/s) a reversion to the mean was interpreted as the displacement of bank storage by rising groundwater levels (corroborated by measurements of specific electrical conductivity). A shorter quarterly study (October 2011 – April 2013) of isotope variations in 15 tributaries with varying geology revealed different responses to evaporation, with a high inverse correlation between Δ18O and baseflow index (BFI) for most of the rivers. A comparison with aquifer waters in the basin showed that even at low flow, rivers rarely consist solely of isotopically unmodified groundwater. Long-term monitoring (2003–2007) of carbon stable isotopes in dissolved inorganic carbon (DIC) in the Thames revealed a complex interplay between respiration, photosynthesis and evasion, but with a mean inter-annual δ13C-DIC value of –14.8 ± 0.5‰, exchange with atmospheric carbon could be ruled out. Quarterly monitoring of the tributaries (October 2011 – April 2013) indicated that in addition to the above factors, river flow variations and catchment characteristics were likely to affect δ13C-DIC. Comparison with basin groundwaters of different alkalinity and δ13C-DIC values showed that the origin of river baseflow is usually obscured. The findings show how long-term monitoring of environmental tracers can help to improve the understanding of how lowland river catchments function

Primary weathering rates, water transit times, and concentration-discharge relations:a theoretical analysis for the critical zone

The permeability architecture of the critical zone exerts a major influence on the hydrogeochemistry of the critical zone. Water flow path dynamics drive the spatiotemporal pattern of geochemical evolution and resulting streamflow concentration-discharge (C-Q) relation, but these flow paths are complex and difficult to map quantitatively. Here we couple a new integrated flow and particle tracking transport model with a general reversible Transition State Theory style dissolution rate law to explore theoretically how C-Q relations and concentration in the critical zone respond to decline in saturated hydraulic conductivity (K-s) with soil depth. We do this for a range of flow rates and mineral reaction kinetics. Our results show that for minerals with a high ratio of equilibrium concentration (C-eq) to intrinsic weathering rate (R-max), vertical heterogeneity in K-s enhances the gradient of weathering-derived solute concentration in the critical zone and strengthens the inverse stream C-Q relation. As C-eq/R-max decreases, the spatial distribution of concentration in the critical zone becomes more uniform for a wide range of flow rates, and stream C-Q relation approaches chemostatic behavior, regardless of the degree of vertical heterogeneity in K-s. These findings suggest that the transport-controlled mechanisms in the hillslope can lead to chemostatic C-Q relations in the stream while the hillslope surface reaction-controlled mechanisms are associated with an inverse stream C-Q relation. In addition, as C-eq/R-max decreases, the concentration in the critical zone and stream become less dependent on groundwater age (or transit time)

Overview of systematic reviews. Effective home support in dementia care: Components and impacts, Stage 1, psychosocial interventions for dementia.

Aim: To synthesise evidence to identify the components of effective psychosocial interventions in dementia care to inform clinical practice, policy and research. Background: With population ageing dementia represents a significant care challenge with 60% of people with dementia living at home. Design: Overview of systematic reviews with narrative summary. Data sources: Electronic searches of published systematic reviews in English using Cochrane Database of Systematic Reviews, DARE, EPPI-Centre, between September 2013 - April 2014. Review methods: Systematic reviews were appraised against Cochrane Collaboration levels of effectiveness. Components of psychosocial interventions were identified with their theoretical rationale. Findings were explored with a Patient, Public and Carer Involvement group. Results: 36 systematic reviews were included. From interventions, 14 components were identified, nine for people with dementia and five for carers, mostly undertaken in nursing/care homes. For people with dementia, there was evidence of effectiveness for cognitive stimulation and cognitive training; but less evidence for sensory stimulation, reminiscence, staff education, behavioural therapy and ADL training. For carers, there was evidence of effectiveness for education and training, psychotherapy and counselling. Conclusion: There was a lack of definitive evidence of effectiveness for most psychosocial interventions. Further studies with stronger methodology or replication of existing studies would strengthen the evidence base. Few interventions were undertaken with people with dementia and their carers living at home. Further work will investigate the extent to which components identified here are present in models of home support for people with dementia and carers and their effectiveness

Palatal development of preterm and low birthweight infants compared to term infants – What do we know? Part 2: The palate of the preterm/low birthweight infant

BACKGROUND: Well-designed clinical studies on the palatal development in preterm and low birthweight infants are desirable because the literature is characterized by contradictory results. It could be shown that knowledge about 'normal' palatal development is still weak as well (Part 1). The objective of this review is therefore to contribute a fundamental analysis of methodologies, confounding factors, and outcomes of studies on palatal development in preterm and low birthweight infants. METHODS: An electronic literature search as well as hand searches were performed based on Cochrane search strategies including sources of more than a century in English, German, and French. Original data were recalculated from studies which primarily dealt with both preterm and term infants. The extracted data, especially those from non-English paper sources, were provided unfiltered for comparison. RESULTS: Seventy-eight out of 155 included articles were analyzed for palatal morphology of preterm infants. Intubation, feeding tubes, feeding mode, tube characteristics, restriction of oral functions, kind of diet, cranial form and birthweight were seen as causes contributing to altered palatal morphology. Changes associated with intubation concern length, depth, width, asymmetry, crossbite, and contour of the palate. The phenomenon 'grooving' has also been described as a complication associated with oral intubation. However, this phenomenon suffers from lack of a clear-cut definition. Head flattening, pressure from the oral tube, pathologic or impaired tongue function, and broadening of the alveolar ridges adjacent to the tube have been raised as causes of 'grooving'. Metrically, the palates of intubated preterm infants remain narrower, which has been examined up to the age of the late mixed dentition. CONCLUSION: There is no evidence that would justify the exclusion of any of the raised causes contributing to palatal alteration. Thus, early orthodontic and logopedic control of formerly orally intubated preterm infants is recommended, as opposed to non-intubated infants. From the orthodontic point of view, nasal intubation should be favored. The role that palatal protection plates and pressure-dispersing pads for the head have in palatal development remains unclear

What is the impact of rerouting a cancer diagnosis from emergency presentation to GP referral on resource use and survival? Evidence from a population-based study

Background: Studies on alternative routes to diagnosis stimulated successful policy interventions reducing the number of emergency diagnoses and associated mortality risk. A dearth of evidence on the costs of such interventions might prevent new policies from achieving more ambitious targets. Methods: We conducted a retrospective cohort study on the population of colorectal (88,051), breast (90,387), prostate (96,219), and lung (97,696) cancer patients diagnosed after a GP referral or an emergency presentation and reported in the Cancer Registry of England. Resource use and survival were compared 1 year before and 5 years after diagnosis (3 years for lung), including the costs of GP referrals not converted into a positive diagnosis. Risk-adjusted statistical models were used to calculate the effect of rerouting patient' diagnoses from emergency presentation to GP referral. Results: Rerouting a cancer diagnosis results in a relatively small additional costs to the National Health System against additional years of life saved to the patient. The cost per year of life saved is £6456 in colorectal, £1057 in breast, £662 in prostate (savings), and £819 in lung cancer. Reducing the overall prevalence of emergency presentations to the level achieved by the 20% of Clinical Commissioning Groups with the lowest prevalence would result in £11,481,948 against 1863 years of life saved for Colorectal, £847,750 against 889 years for breast, £943,434 (cost savings) against 1195 years for prostate, and £609,938 against 1011 years for lung cancer. Conclusion: Redirecting diagnoses from emergency presentation to GP referral appears an achievable target that can produce large benefits to patients against modest additional costs to the National Health System