Análisis físico-químico y fitoplanctónico de la ciénaga Puerto Caimán, vertiente Caribe, Colombia

The environmental conditions in the Puerto Caiman marsh, Caribbean slope, Colombia, were evaluated, taking into account the physical-chemical variables and their influence on the taxocenosis of the marsh's phytoplankton. Five stations were established, taking into account general characteristics of the body of water (stream and seawater entry, morphology and extension). In each of the stations, 24 L of surface water were filtered, with a pore diameter mesh of 24 μm for the phytoplankton collection, additionally physical-chemical variables were registered in situ and environmental pollution indices evaluated. The behavior of physico-chemical variables such as alkalinity, conductivity, total suspended solids, pH, dissolved oxygen and water temperature showed variation in the body of water. The composition of the phytoplankton recorded changes in richness y density. The highest density (1045 Cél.mL-1) was observed in the third sample, dominated by Nitzschia acicularis (994 Cél.mL-1), species with the highest density in all the samplings (1031 Cél.mL-1), followed by Entomoneis alata (243 Cél.mL-1) and Anabaena flos-aquae (181 Cél.mL-1). environmental pollution indices evidenced contamination in the Puerto Caiman marsh due to the effects of total suspended solids (ICOSUS), mineralization (ICOMI) and anthropogenic effects such as livestock, destruction of riparian vegetation and domestic dumping. The Puerto Caiman marsh is a polluted-eutrophied environment, characterized by several species of phytoplankton previously reported for some authors as an indicator of polluted water.Se evaluaron las condiciones ambientales en la ciénaga de Puerto Caimán, vertiente Caribe, Colombia, teniendo en cuenta las variables físico-químicas y su influencia en la taxocenosis del fitoplancton de la ciénaga. Cinco estaciones fueron establecidas, teniendo en cuenta algunas características del cuerpo de agua (entrada de arroyos y agua de mar, morfología y extensión). En cada una de las estaciones, se filtraron 24 L de agua superficial, con una malla de diámetro de poro de 24 μm para la recolección de fitoplancton. Adicionalmente, se registraron in situ variables físico-químicas y se evaluaron índices de contaminación ambiental (ICOS). El comportamiento de variables físico-químicas tales como alcalinidad, conductividad, sólidos totales suspendidos, pH, oxígeno disuelto y temperatura superficial del agua mostró variación espacio-temporal en el cuerpo de agua. La composición del fitoplancton registró cambios en la riqueza y densidad. La mayor densidad (1,045 Cél.mL-1) se observó en el tercer muestreo. Nitzschia acicularis presentó la mayor densidad en todos los muestreos (994 Cél.mL-1), seguida por Entomoneis alata (243 Cél.mL-1) y Anabaena flos-aquae (181 Cél.mL-1). Los ICOS, por su parte, evidenciaron contaminación en la ciénaga de Puerto Caimán por efectos de los sólidos totales suspendidos (ICOSUS), la mineralización (ICOMI) y efectos antrópicos tales como la ganadería, destrucción de la vegetación ribereña y vertimientos domésticos. La ciénaga de Puerto Caimán es un ambiente contaminado-eutrofizado, caracterizado por especies de fitoplancton que han sido reportadas como indicadores de aguas contaminadas

Development of an activity disease score in patients with uveitis (UVEDAI)

To develop a disease activity index for patients with uveitis (UVEDAI) encompassing the relevant domains of disease activity considered important among experts in this field. The steps for designing UVEDAI were: (a) Defining the construct and establishing the domains through a formal judgment of experts, (b) A two-round Delphi study with a panel of 15 experts to determine the relevant items, (c) Selection of items: A logistic regression model was developed that set ocular inflammatory activity as the dependent variable. The construct "uveitis inflammatory activity" was defined as any intraocular inflammation that included external structures (cornea) in addition to uvea. Seven domains and 15 items were identified: best-corrected visual acuity, inflammation of the anterior chamber (anterior chamber cells, hypopyon, the presence of fibrin, active posterior keratic precipitates and iris nodules), intraocular pressure, inflammation of the vitreous cavity (vitreous haze, snowballs and snowbanks), central macular edema, inflammation of the posterior pole (the presence and number of choroidal/retinal lesions, vascular inflammation and papillitis), and global assessment from both (patient and physician). From all the variables studied in the multivariate model, anterior chamber cell grade, vitreous haze, central macular edema, inflammatory vessel sheathing, papillitis, choroidal/retinal lesions and patient evaluation were included in UVEDAI. UVEDAI is an index designed to assess the global ocular inflammatory activity in patients with uveitis. It might prove worthwhile to motorize the activity of this extraarticular manifestation of some rheumatic diseases

Phenological Study of 53 Spanish Minority Grape Varieties to Search for Adaptation of Vitiviniculture to Climate Change Conditions

The main phenological stages (budburst, flowering, veraison, and ripeness) of 53 Spanish minority varieties were studied to determine their potential to help winegrowers adapt to climate change conditions. In total, 43 varieties were studied in the same location in Spain (Alcalá de Henares, in the Madrid region) and 10 varieties in 5 other regions (Galicia, Navarre, Catalonia, Extremadura, and Andalusia). Other traits of agronomic and oenological interest, such as yield and acidity, were also monitored. The results allow for the grouping of the varieties into several clusters according to the time of ripeness (very early—only for red varieties—and early, intermediate, and late, for both red and white varieties) and yield (high, medium, and low). The total acidity in the grape juice ranged from 3 to 11 g of tartaric acid/L. The average temperatures were higher (up to 3–4 °C during summer) compared to historical averages during the 1957–2021 time period. Advanced phenology phases and reduced acidity are regarded as negative effects of climate change for winegrowing practices. Since some minority varieties showed late or intermediate ripening, high acidity, and high (1 Kg/shoot) or medium (0.5 Kg/shoot) yield, our findings suggest that they may be cultivated in the coming years by winegrowers as an approach to mitigate climate change effects.Project RTI2018-101085-R-C31, “Valorization of Minority Grapevine Varieties for their Potential for Wine Diversification and Resilience to Climate Change (MINORVIN),” funded by MCIN/AEI/10.13039/501100011033, and by the ERDF, A Way to Make Europe.Peer reviewe

Reflections Magazine of the Faculty of Education. Volume 7 No. 8 June 1999

Reflexiones presenta en esta entrega artículos escritos por profesores y alumnos de los programas de posgrado y pregrado de nuestra Facultad, en los cuales se plasma el espíritu de una comunidad académica deseosa de contribuir al desarrollo de lo humano, utilizando como pretexto puntos de referencia de orden ético y lógico, en consonancia con los ideales que propone, para el hacerteórico y práctico, el Proyecto Educativo de nuestra Universidad. Además, através deestas líneas iniciales, el comité curricular de la Facultad desea informar a los lectores sobre el proceso de autoevalución y acreditación que estamos viviendo, e invitar a los profesores y alumnos, al personal administrativo y a los egresados de esa facultad y a la comunidad académica de la escuelanormal de Bucaramanga, a participar en el análisis y consecuente reestructuración de los programas que ofrecemos.Reflections presents in this installment articles written by professors and students of the postgraduate and undergraduate programs of our Faculty, in which the spirit of an academic community eager to contribute to the development of the human being is embodied, using reference points of order as a pretext. ethical and logical, in line with the ideals proposed, for the theoretical and practical, the Educational Project of our University. In addition, through these initial lines, the Faculty's curricular committee wishes to inform readers about the self-evaluation and accreditation process that we are undergoing, and invite teachers and students, administrative staff and graduates of that Faculty and the academic community of the normal school of Bucaramanga, to participate in the analysis and consequent restructuring of the programs we offer

Effectiveness of an intervention for improving drug prescription in primary care patients with multimorbidity and polypharmacy:Study protocol of a cluster randomized clinical trial (Multi-PAP project)

This study was funded by the Fondo de Investigaciones Sanitarias ISCIII (Grant Numbers PI15/00276, PI15/00572, PI15/00996), REDISSEC (Project Numbers RD12/0001/0012, RD16/0001/0005), and the European Regional Development Fund ("A way to build Europe").Background: Multimorbidity is associated with negative effects both on people's health and on healthcare systems. A key problem linked to multimorbidity is polypharmacy, which in turn is associated with increased risk of partly preventable adverse effects, including mortality. The Ariadne principles describe a model of care based on a thorough assessment of diseases, treatments (and potential interactions), clinical status, context and preferences of patients with multimorbidity, with the aim of prioritizing and sharing realistic treatment goals that guide an individualized management. The aim of this study is to evaluate the effectiveness of a complex intervention that implements the Ariadne principles in a population of young-old patients with multimorbidity and polypharmacy. The intervention seeks to improve the appropriateness of prescribing in primary care (PC), as measured by the medication appropriateness index (MAI) score at 6 and 12months, as compared with usual care. Methods/Design: Design:pragmatic cluster randomized clinical trial. Unit of randomization: family physician (FP). Unit of analysis: patient. Scope: PC health centres in three autonomous communities: Aragon, Madrid, and Andalusia (Spain). Population: patients aged 65-74years with multimorbidity (≥3 chronic diseases) and polypharmacy (≥5 drugs prescribed in ≥3months). Sample size: n=400 (200 per study arm). Intervention: complex intervention based on the implementation of the Ariadne principles with two components: (1) FP training and (2) FP-patient interview. Outcomes: MAI score, health services use, quality of life (Euroqol 5D-5L), pharmacotherapy and adherence to treatment (Morisky-Green, Haynes-Sackett), and clinical and socio-demographic variables. Statistical analysis: primary outcome is the difference in MAI score between T0 and T1 and corresponding 95% confidence interval. Adjustment for confounding factors will be performed by multilevel analysis. All analyses will be carried out in accordance with the intention-to-treat principle. Discussion: It is essential to provide evidence concerning interventions on PC patients with polypharmacy and multimorbidity, conducted in the context of routine clinical practice, and involving young-old patients with significant potential for preventing negative health outcomes. Trial registration: Clinicaltrials.gov, NCT02866799Publisher PDFPeer reviewe

Role of age and comorbidities in mortality of patients with infective endocarditis

[Purpose]: The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality. [Methods]: Prospective cohort study of all patients with IE included in the GAMES Spanish database between 2008 and 2015.Patients were stratified into three age groups:<65 years,65 to 80 years,and ≥ 80 years.The area under the receiver-operating characteristic (AUROC) curve was calculated to quantify the diagnostic accuracy of the CCI to predict mortality risk. [Results]: A total of 3120 patients with IE (1327 < 65 years;1291 65-80 years;502 ≥ 80 years) were enrolled.Fever and heart failure were the most common presentations of IE, with no differences among age groups.Patients ≥80 years who underwent surgery were significantly lower compared with other age groups (14.3%,65 years; 20.5%,65-79 years; 31.3%,≥80 years). In-hospital mortality was lower in the <65-year group (20.3%,<65 years;30.1%,65-79 years;34.7%,≥80 years;p < 0.001) as well as 1-year mortality (3.2%, <65 years; 5.5%, 65-80 years;7.6%,≥80 years; p = 0.003).Independent predictors of mortality were age ≥ 80 years (hazard ratio [HR]:2.78;95% confidence interval [CI]:2.32–3.34), CCI ≥ 3 (HR:1.62; 95% CI:1.39–1.88),and non-performed surgery (HR:1.64;95% CI:11.16–1.58).When the three age groups were compared,the AUROC curve for CCI was significantly larger for patients aged <65 years(p < 0.001) for both in-hospital and 1-year mortality. [Conclusion]: There were no differences in the clinical presentation of IE between the groups. Age ≥ 80 years, high comorbidity (measured by CCI),and non-performance of surgery were independent predictors of mortality in patients with IE.CCI could help to identify those patients with IE and surgical indication who present a lower risk of in-hospital and 1-year mortality after surgery, especially in the <65-year group

Implantación de un sistema integral de gestión del conocimiento para los procesos de innovación docente de la Universidad de Salamanca

Memoria ID-0312. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2014-2015

Implantación de un sistema integral de gestión del conocimiento para los procesos de innovación docente de la Universidad de Salamanca

Memoria ID-0312. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2014-2015

Ahora / Ara

La cinquena edició del microrelatari per l’eradicació de la violència contra les dones de l’Institut Universitari d’Estudis Feministes i de Gènere «Purificación Escribano» de la Universitat Jaume I vol ser una declaració d’esperança. Aquest és el moment en el qual les dones (i els homes) hem de fer un pas endavant i eliminar la violència sistèmica contra les dones. Ara és el moment de denunciar el masclisme i els micromasclismes començant a construir una societat més igualitària. Cadascun dels relats del llibre és una denúncia i una declaració que ens encamina cap a un món millor

Pasados y presente. Estudios para el profesor Ricardo García Cárcel

Ricardo García Cárcel (Requena, 1948) estudió Historia en Valencia bajo el magisterio de Joan Reglà, con quien formó parte del primer profesorado de historia moderna en la Universidad Autónoma de Barcelona. En esta universidad, desde hace prácticamente cincuenta años, ha desarrollado una extraordinaria labor docente y de investigación marcada por un sagaz instinto histórico, que le ha convertido en pionero de casi todo lo que ha estudiado: las Germanías, la historia de la Cataluña moderna, la Inquisición, las culturas del Siglo de Oro, la Leyenda Negra, Felipe II, Felipe V, Austrias y Borbones, la guerra de la Independencia, la historia cultural, los mitos de la historia de España... Muy pocos tienen su capacidad para reflexionar, ordenar, analizar, conceptualizar y proponer una visión amplia y llena de matices sobre el pasado y las interpretaciones historiográficas. A su laboriosidad inimitable se añade una dedicación sin límites en el asesoramiento de alumnos e investigadores e impulsando revistas, dosieres, seminarios o publicaciones colectivas. Una mínima correspondencia a su generosidad lo constituye este volumen a manera de ineludible agradecimiento