Comportamiento productivo, reproductivo y química sanguínea de novillas de reemplazo Brahman a pastoreo suplementadas con ácidos grasos y proteína

To evaluate the effect of calcium salts of long-chain fatty acids (CaLCFA) and protein supplementation on body weight (BW), average daily gain (ADG), pregnancy rate (PR), and blood chemistry, 57 Brahman heifers with 309.1 ± 3.04 kg BW and 1,010 ± 8.51 days of age, were divided into three BW uniform groups and assigned for 102 days to three treatments under a completely randomized design: 1) grazing forage only (F); 2) F+CaLCFA, and 3) F+CaLCFA+protein-energy mix (CaLCFA+CP) with 453 protein g/kg, containing mainly (g/kg) CaLCFA (200), hydrolyzed feather meal (300), and cornmeal (375). About 0.2 and 1 kg/animal/d of CaLCFA and CaLCFA+CP were offered, respectively, with an average intake of 200 and 192 g/animal/d for the same order of supplements. The breeding period (BP) lasted for 45 days and started 57 days after beginning the supplementation period. Body weight showed a treatment × time interaction (p < 0.01), being different at the end of the BP (348; 338 and 331 kg, respectively for CaLCFA, CaLCFA+CP, and F). Average daily gain (g/d) was higher (p < 0.01) for CaLCFA (358) than for CaLCFA+CP (281), and lower for F (206). Overall, PR was higher (p < 0.05) for CaLCFA+CP (68.4 %) and lower for F (36.8 %). Cholesterol (mg/dL) was higher (p < 0.05) for CaLCFA+CP (139) and lower for F (117). Calcium salts of long-chain fatty acids and CaLCFA+CP supplementation improved BW and ADG of Brahman heifers at first mating, while PR and cholesterol increased only with CaLCFA+CP supplementation.Para evaluar el efecto de la suplementación con sales de calcio de ácidos grasos de cadena larga (CaAGCL) y la adición de proteína, sobre peso vivo (PV), ganancia diaria de peso (GDP), porcentaje de preñez (PP) y química sanguínea, 57 novillas Brahman con PV de 309,1 ± 3,04 kg y 1.010 ± 8,51 días de edad, fueron divididas en tres grupos uniformes en peso y asignados a tres tratamientos durante 102 días siguiendo un diseño completamente aleatorio: 1) animales pastando forraje (F); 2) F+CaAGCL y 3) F+ suplementación con mezcla energética-proteica (CaAGCL+PC) de 453 g proteína/kg, conformada principalmente (g/kg) por CaAGCL (200), harina de pluma hidrolizada (300), harina de maíz (375). Se ofertaron 0,2 y 1 kg/animal/d de CaAGCL y CaAGCL+PC, respectivamente, con un consumo promedio de 200 y 192 g/animal/d para el mismo orden de suplementos. La temporada de servicio (TS) fue de 45 días y comenzó el día 57 de iniciada la suplementación. El PV mostró interacción tratamiento × tiempo (p < 0,01) siendo diferentes al final de la TS (348; 338 y 331 kg para CaAGCL, CaAGCL+PC y F, respectivamente). La GDP (g/d) fue mayor (p < 0,01) en CaAGCL (358) seguida por CaAGCL+PC (281) y más baja en F (206). El PP general fue mayor (p < 0,05) en CaAGCL+PC (68,4 %) y más bajo en F (31,6 %). El colesterol (mg/dL) fue mayor (p < 0,05) en CaAGCL+PC (139) y más bajo en F (117). La suplementación con CaAGCL y CaAGCL+PC mejora el PV y GDP de novillas Brahman de primer servicio, mientras el PP y colesterol se incrementa solo con la suplementación con AGCL+PC

Da produção à preservação informacional: desafios e oportunidades

This book focus in the study of past information systems, current information management and digital preservation. It results from a set of text sources, whose approaches reflect the challenges and opportunities in the world of information, treated by specialists dealing with it on a professional and academic level. The objective of this collection of text sources is to be a motto to new contributions to the archival field, potentiating experiences in the work context and new studies in the approached thematics

The surgical safety checklist and patient outcomes after surgery: a prospective observational cohort study, systematic review and meta-analysis

© 2017 British Journal of Anaesthesia Background: The surgical safety checklist is widely used to improve the quality of perioperative care. However, clinicians continue to debate the clinical effectiveness of this tool. Methods: Prospective analysis of data from the International Surgical Outcomes Study (ISOS), an international observational study of elective in-patient surgery, accompanied by a systematic review and meta-analysis of published literature. The exposure was surgical safety checklist use. The primary outcome was in-hospital mortality and the secondary outcome was postoperative complications. In the ISOS cohort, a multivariable multi-level generalized linear model was used to test associations. To further contextualise these findings, we included the results from the ISOS cohort in a meta-analysis. Results are reported as odds ratios (OR) with 95% confidence intervals. Results: We included 44 814 patients from 497 hospitals in 27 countries in the ISOS analysis. There were 40 245 (89.8%) patients exposed to the checklist, whilst 7508 (16.8%) sustained ≥1 postoperative complications and 207 (0.5%) died before hospital discharge. Checklist exposure was associated with reduced mortality [odds ratio (OR) 0.49 (0.32–0.77); P\u3c0.01], but no difference in complication rates [OR 1.02 (0.88–1.19); P=0.75]. In a systematic review, we screened 3732 records and identified 11 eligible studies of 453 292 patients including the ISOS cohort. Checklist exposure was associated with both reduced postoperative mortality [OR 0.75 (0.62–0.92); P\u3c0.01; I2=87%] and reduced complication rates [OR 0.73 (0.61–0.88); P\u3c0.01; I2=89%). Conclusions: Patients exposed to a surgical safety checklist experience better postoperative outcomes, but this could simply reflect wider quality of care in hospitals where checklist use is routine

Prospective observational cohort study on grading the severity of postoperative complications in global surgery research

Background The Clavien–Dindo classification is perhaps the most widely used approach for reporting postoperative complications in clinical trials. This system classifies complication severity by the treatment provided. However, it is unclear whether the Clavien–Dindo system can be used internationally in studies across differing healthcare systems in high- (HICs) and low- and middle-income countries (LMICs). Methods This was a secondary analysis of the International Surgical Outcomes Study (ISOS), a prospective observational cohort study of elective surgery in adults. Data collection occurred over a 7-day period. Severity of complications was graded using Clavien–Dindo and the simpler ISOS grading (mild, moderate or severe, based on guided investigator judgement). Severity grading was compared using the intraclass correlation coefficient (ICC). Data are presented as frequencies and ICC values (with 95 per cent c.i.). The analysis was stratified by income status of the country, comparing HICs with LMICs. Results A total of 44 814 patients were recruited from 474 hospitals in 27 countries (19 HICs and 8 LMICs). Some 7508 patients (16·8 per cent) experienced at least one postoperative complication, equivalent to 11 664 complications in total. Using the ISOS classification, 5504 of 11 664 complications (47·2 per cent) were graded as mild, 4244 (36·4 per cent) as moderate and 1916 (16·4 per cent) as severe. Using Clavien–Dindo, 6781 of 11 664 complications (58·1 per cent) were graded as I or II, 1740 (14·9 per cent) as III, 2408 (20·6 per cent) as IV and 735 (6·3 per cent) as V. Agreement between classification systems was poor overall (ICC 0·41, 95 per cent c.i. 0·20 to 0·55), and in LMICs (ICC 0·23, 0·05 to 0·38) and HICs (ICC 0·46, 0·25 to 0·59). Conclusion Caution is recommended when using a treatment approach to grade complications in global surgery studies, as this may introduce bias unintentionally

Critical care admission following elective surgery was not associated with survival benefit: prospective analysis of data from 27 countries

This was an investigator initiated study funded by Nestle Health Sciences through an unrestricted research grant, and by a National Institute for Health Research (UK) Professorship held by RP. The study was sponsored by Queen Mary University of London

Delaying surgery for patients with a previous SARS-CoV-2 infection

Not availabl