Cross-layer Based MANET Performance Optimization for Different Traffic and Mobility Scenario

The self configuring dexterous autonomy of MANET imposes some network challenges constrained to traditional dynamic routing behaviour. So as working with different mobility and traffic patterns with normal management schemes may lead some minor pitfalls to some important network performance parameters and hence can degrade the whole network performance. Here,  Our aim is to make some DSR and MAC based cross layer optimizations and testify it on different mobility and traffic scenarios so as to justify the robustness of our proposed improvement. Keywords— Cross- Layer, DSR, MAC, MANET, Optimizatio

Quality of Service Optimization in Realm of Green Monitoring using Broad Area Sensor Network (BASN)

A Wireless Sensor Network(WSN) contains short range energy limited terminals/nodes in which multiple nodes participates one by one to transfer data from source node to Base station. Each node appends some amount of delay which degrades the network performance as the jittered behaviour of network may not be allowed in some applications. Again the faulty nature of tandem nodes may create some severe routing scenarios.  Concept of Broad Area Sensor Network (BASN) incorporates a real time communication between sensor node and Base station, which helps to optimize the Quality of Service (QoS). Our goal is to do extensive simulation on performance analysis of such sensor networks and its optimization. Keywords -  WSN ,energy limited terminals, jitter, Quality of service(QoS

Body Sensor Network: A Modern Survey & Performance Study in Medical Perspect

As because of modern emerging technologies, low power integrated circuits and wireless communication has enabled a new generation of sensors network. The incorporation of these sensors networks in Health care is very popular and plays a vital role in breath breaking situations. The deployment of monitoring hardware incorporated with various wireless standards plays a key role in regard to interoperability, invasion privacy, sensors validation data consistency and interference related issues. The goal of our paper is to make a comparative study in realm of modern wireless trends such as Bluetooth, Wi-fi, Zigbee and Wibree and related facets. Index Terms– Wireless Body area network, Zigbee, Wi-fi, Bluetooot

Nimotuzumab-cisplatin-radiation versus cisplatin-radiation in HPV negative oropharyngeal cancer

BACKGROUND: Addition of nimotuzumab to weekly cisplatin and radiation improves outcomes in head and neck cancer. HPV negative oropharyngeal cancer has unsatisfactory treatment outcomes and is a candidate for escalation of treatment. We wanted to determine whether the addition of nimotuzumab to cisplatin-radiation could improve outcomes in these poor-risk tumors.METHODS: This was a subgroup analysis of a phase 3 randomized study. In this study, locally advanced head and neck cancer patients undergoing definitive chemoradiation were randomly allocated to weekly cisplatin (30 mg/m2 IV)- radiation (66–70 Gy) {CRT arm} or nimotuzumab (200 mg weekly) -weekly cisplatin (30 mg/m2)-radiation (66–70 Gy) {NCRT arm}. The data of HPV negative oropharyngeal cancer was extracted from the database of this study for the analysis. HPV testing was done with p16 immunohistochemistry (IHC) staining and reported according to the CAP criteria. The outcomes assessed were progression-free survival (PFS), disease-free survival (DFS), locoregional control, and overall survival (OS). Interaction test was performed between the study arms and HPV status prior to doing any HPV specific analysis for each of the studied outcomes. Kaplan Meier estimates for 2 year OS with 95% CI was calculated. The hazard ratio was obtained using COX regression analysis.RESULTS: We had 187 HPV negative oropharyngeal cancers, 91 in the CRT arm and 96 in NCRT arm. The interaction test was significant for PFS (p = 0.000), locoregional control (p = 0.007) and overall survival (p = 0.002) but not for DFS (p = 0.072). The 2- year PFS was 31.5% (95%CI 21.5–42) in CRT arm versus 57.2% (95%CI 45.8–67.1) in NCRT arm (HR -0.54; 95%CI 0.36–0.79, p = 0.002). The 2-year LRC was 41.4% (95%CI 29.8–52.6) in the CRT arm versus in 60.4% (95%CI 48.7–70.2) in the NCRT arm (HR -0.61; 95%CI 0.4–0.94, p = 0.024). The addition of nimotuzumab also lead to an improvement in 2-year OS from 39.0% (95%CI 28.4–49.6) to 57.6% (95%CI 46.3–67.4) (HR-0.63, 95%CI 0.43–0.92, p = 0.018).CONCLUSIONS: The addition of nimotuzumab to weekly cisplatin-radiation improves outcomes inclusive of OS in HPV negative oropharyngeal cancers.<br/

Nimotuzumab-cisplatin-radiation versus cisplatin-radiation in HPV negative oropharyngeal cancer

BACKGROUND: Addition of nimotuzumab to weekly cisplatin and radiation improves outcomes in head and neck cancer. HPV negative oropharyngeal cancer has unsatisfactory treatment outcomes and is a candidate for escalation of treatment. We wanted to determine whether the addition of nimotuzumab to cisplatin-radiation could improve outcomes in these poor-risk tumors.METHODS: This was a subgroup analysis of a phase 3 randomized study. In this study, locally advanced head and neck cancer patients undergoing definitive chemoradiation were randomly allocated to weekly cisplatin (30 mg/m2 IV)- radiation (66–70 Gy) {CRT arm} or nimotuzumab (200 mg weekly) -weekly cisplatin (30 mg/m2)-radiation (66–70 Gy) {NCRT arm}. The data of HPV negative oropharyngeal cancer was extracted from the database of this study for the analysis. HPV testing was done with p16 immunohistochemistry (IHC) staining and reported according to the CAP criteria. The outcomes assessed were progression-free survival (PFS), disease-free survival (DFS), locoregional control, and overall survival (OS). Interaction test was performed between the study arms and HPV status prior to doing any HPV specific analysis for each of the studied outcomes. Kaplan Meier estimates for 2 year OS with 95% CI was calculated. The hazard ratio was obtained using COX regression analysis.RESULTS: We had 187 HPV negative oropharyngeal cancers, 91 in the CRT arm and 96 in NCRT arm. The interaction test was significant for PFS (p = 0.000), locoregional control (p = 0.007) and overall survival (p = 0.002) but not for DFS (p = 0.072). The 2- year PFS was 31.5% (95%CI 21.5–42) in CRT arm versus 57.2% (95%CI 45.8–67.1) in NCRT arm (HR -0.54; 95%CI 0.36–0.79, p = 0.002). The 2-year LRC was 41.4% (95%CI 29.8–52.6) in the CRT arm versus in 60.4% (95%CI 48.7–70.2) in the NCRT arm (HR -0.61; 95%CI 0.4–0.94, p = 0.024). The addition of nimotuzumab also lead to an improvement in 2-year OS from 39.0% (95%CI 28.4–49.6) to 57.6% (95%CI 46.3–67.4) (HR-0.63, 95%CI 0.43–0.92, p = 0.018).CONCLUSIONS: The addition of nimotuzumab to weekly cisplatin-radiation improves outcomes inclusive of OS in HPV negative oropharyngeal cancers.<br/

महिषासुर: मिथक व परंपराएं

इक्कसवीं सदी के दूसरे दशक में भारत में महिषासुर आंदोलन द्विज संस्कृति के लिए चुनौती बनकर उभरा। इसके माध्यम से आदिवासियों, पिछड़ों और दलितों के एक बड़े हिस्से ने अपनी सांस्कृतिक दावेदारी पेश की। लेकिन यह आंदोलन क्या है, इसकी जड़ें समाज में कहां तक फैली हैं, बहुजनों की सांस्कृतिक परंपरा में इसका क्या स्थान है, मौजूदा लोक-जीवन में महिषासुर की उपस्थिति किन-किन रूपों में है, इसके पुरातात्विक साक्ष्य क्या हैं? गीतों-कविताओं व नाटकों में महिषासुर किस रूप में याद किए जा रहे हैं और अकादमिक-बौद्धिक वर्ग को इस आंदोलन ने किस रूप में प्रभावित किया है, उनकी प्रतिक्रियाएं क्या हैं? आदि प्रश्नों पर विमर्श हमें एक ऐसी बौद्धिक यात्रा की ओर ले जाने में सक्षम हैं, जिससे हममें अधिकांश अभी तक अपरिचित रहे हैं। क्या महिषासुर दक्षिण एशिया के अनार्यों के पूर्वज थे, जो बाद में एक मिथकीय चरित्र बन कर बहुजन संस्कृति के प्रतीक पुरुष बन गए? क्या यह बहुत बाद की परिघटना है, जब माकण्डेय पुराण, दुर्गासप्तशती जैसे ग्रंथ रच कर, एक कपोल-कल्पित देवी के हाथों महिषासुर की हत्या की कहानी गढ़ी गई? इस आंदोलन की सैद्धांतिकी क्या है? प्रमोद रंजन द्वारा संपादित किताब “महिषासुर: मिथक व परंपराएं” में लेखकों ने उपरोक्त प्रश्नों पर विचार किया है तथा विलुप्ति के कगार पर खड़े असुर समुदाय का विस्तृत नृवंशशास्त्रीय अध्ययन भी प्रस्तुत किया है। इस पुस्तक में समकालीन भारतीय साहित्य में महिषासुर पर लिखी गई कविताओं व गीतों का प्रतिनिधि संकलन भी है तथा महिषासुर की बहुजन कथा पर आधारित एक नाटक भी प्रकाशित है। समाज-विज्ञान व सांस्कृतिक विमर्श के अध्येताओं, सामाजिक-राजनीतिक कार्यकर्ताओं, साहित्य प्रेमियों के लिए यह एक आवश्यक पुस्तक है

Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017.

BACKGROUND: Global development goals increasingly rely on country-specific estimates for benchmarking a nation's progress. To meet this need, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 estimated global, regional, national, and, for selected locations, subnational cause-specific mortality beginning in the year 1980. Here we report an update to that study, making use of newly available data and improved methods. GBD 2017 provides a comprehensive assessment of cause-specific mortality for 282 causes in 195 countries and territories from 1980 to 2017. METHODS: The causes of death database is composed of vital registration (VR), verbal autopsy (VA), registry, survey, police, and surveillance data. GBD 2017 added ten VA studies, 127 country-years of VR data, 502 cancer-registry country-years, and an additional surveillance country-year. Expansions of the GBD cause of death hierarchy resulted in 18 additional causes estimated for GBD 2017. Newly available data led to subnational estimates for five additional countries-Ethiopia, Iran, New Zealand, Norway, and Russia. Deaths assigned International Classification of Diseases (ICD) codes for non-specific, implausible, or intermediate causes of death were reassigned to underlying causes by redistribution algorithms that were incorporated into uncertainty estimation. We used statistical modelling tools developed for GBD, including the Cause of Death Ensemble model (CODEm), to generate cause fractions and cause-specific death rates for each location, year, age, and sex. Instead of using UN estimates as in previous versions, GBD 2017 independently estimated population size and fertility rate for all locations. Years of life lost (YLLs) were then calculated as the sum of each death multiplied by the standard life expectancy at each age. All rates reported here are age-standardised

महिषासुर: एक जननायक

International audienceThis is the English edition of the book 'Mahishasur: Ek Jannayak'. The book searches for a hero who has been ever-present in the memories, traditions, festivals, and celebrations of a majority of the people of India but who the dominant culture of the country has given the image of a villain. Recently, the search for this people's hero triggered a debate in Parliament. The book asks, "Why is there a celebration of death?" The Hindi version of this book can be found at HAL here: https://hal.science/hal-0374996

बहुजन साहित्य की प्रस्तावना (हिंदी)

International audienceThis book presents a discussion on the concept of Bahujan literature in Hindi and Indian languages. On the one hand, this book monitors the changes taking place in Hindi literature, on the other hand, outlines the basic elements of the new debate that started in the field of literature in relation to the changing social and political scenarios after the implementation of the Mandal Commission. In today's Indian perspective, the Bahujan sections are – Other Backward Classes, Scheduled Tribes, Scheduled Castes, Denotified Nomadic Castes, Pasmanda Minorities and Women. The concept of Bahujan literature sees similarity in all these sufferings and finds the causes of their exploitation more or less similar. This book is as important for the researchers of literature as it is for the conscious people who aspire to understand the literary perspective and also for those who consider themselves a part of the Bahujan community. This book answers all the questions related to Bahujan discourse.his book was originally published in Hindi in the year 2016. Its English translation was also published in the same year, with the title "The Case For Bahujan Literature".The English translation of this book can be found on HAL here: https://hal.science/hal-03752562/यह किताब हिन्दी और भारतीय भाषाओं में बहुजन साहित्य की अवधारणा पर विमर्श प्रस्तुत करती है। एक ओर यह किताब हिंदी साहित्य में हो रहे बदलावों पर नजर रखती है दूसरी ओर मंडल कमीशन के लागू होने के बाद बदल रहे समाज व राजनीतिक परिदृश्यों के सापेक्ष साहित्य के क्षेत्र में शुरू हुई नई बहस के बुनियादी तत्वों को रेखांकित भी करती है। आज के भारतीय परिप्रेक्ष्य में बहुजन तबके हैं- अन्य पिछड़ा वर्ग, अनुसूचित जनजातियां, अनुसूचित जातियां, विमुक्त घूमंतू जातियां, पसमांदा अल्पसंख्यक व स्त्रियां । बहुजन साहित्य की अवधारणा इन सभी की पीड़ाओं में समानता देखती है तथा इनके शोषण के कारणों को कमोबेश समान पाती है। यह किताब साहित्य के शोधार्थियों के लिए जितना महत्वपूर्ण है, उतना ही साहित्यिक नजरिए को समझने की आकंक्षा रखने वाले जागरूक लोगों के लिए भी और उनके लिए भी जो स्वयं को बहुजन का हिस्सा मानते हैं। फिर चाहे वे सामाजिक कार्यकर्ता हों या फिर राजनेता। बहुजन विमर्श से जुड‍़े सभी सवालों का यह किताब उत्तर देती है।यह किताब वर्ष 2016 में हिंदी में प्रकाशित हुई थी। उसी साल इसका अंग्रेजी अनुवाद भी "The Case For Bahujan Literature" शीर्षक से प्रकाशित हुआ।इस किताब का अंग्रेजी अनुवाद HAL पर यहां देखा जा सकता है: https://hal.science/hal-03752562

बहुजन साहित्य की प्रस्तावना

International audienceThis book was originally published in Hindi with the title 'Bahujan Sahitya ki Prastavan" [Introduction to Bahujan Literature] in the year 2016. Its English translation was also published in the same year.This book presents a discussion on the concept of Bahujan literature in Hindi and Indian languages. On the one hand, this book monitors the changes taking place in Hindi literature, on the other hand, outlines the basic elements of the new debate that started in the field of literature in relation to the changing social and political scenarios after the implementation of the Mandal Commission. In today's Indian perspective, the Bahujan sections are – Other Backward Classes, Scheduled Tribes, Scheduled Castes, Denotified Nomadic Castes, Pasmanda Minorities and Women. The concept of Bahujan literature sees similarity in all these sufferings and finds the causes of their exploitation more or less similar. This book is as important for the researchers of literature as it is for the conscious people who aspire to understand the literary perspective and also for those who consider themselves a part of the Bahujan community. This book answers all the questions related to Bahujan discourse.यह पुस्तक मूल रूप से हिंदी में वर्ष 2016 में 'बहुजन साहित्य की प्रस्तावना' शीर्षक से प्रकाशित हुई थी। उसका यह अंग्रेजी अनुवाद भी उसी वर्ष प्रकाशित हुआ था।यह किताब हिन्दी और भारतीय भाषाओं में बहुजन साहित्य की अवधारणा पर विमर्श प्रस्तुत करती है। एक ओर यह किताब हिंदी साहित्य में हो रहे बदलावों पर नजर रखती है दूसरी ओर मंडल कमीशन के लागू होने के बाद बदल रहे समाज व राजनीतिक परिदृश्यों के सापेक्ष साहित्य के क्षेत्र में शुरू हुई नई बहस के बुनियादी तत्वों को रेखांकित भी करती है। आज के भारतीय परिप्रेक्ष्य में बहुजन तबके हैं- अन्य पिछड़ा वर्ग, अनुसूचित जनजातियां, अनुसूचित जातियां, विमुक्त घूमंतू जातियां, पसमांदा अल्पसंख्यक व स्त्रियां । बहुजन साहित्य की अवधारणा इन सभी की पीड़ाओं में समानता देखती है तथा इनके शोषण के कारणों को कमोबेश समान पाती है। यह किताब साहित्य के शोधार्थियों के लिए जितना महत्वपूर्ण है, उतना ही साहित्यिक नजरिए को समझने की आकंक्षा रखने वाले जागरूक लोगों के लिए भी और उनके लिए भी जो स्वयं को बहुजन का हिस्सा मानते हैं। फिर चाहे वे सामाजिक कार्यकर्ता हों या फिर राजनेता। बहुजन विमर्श से जुड‍़े सभी सवालों का यह किताब उत्तर देती है