Impacto de las actividades de construcción de puertos en la estructura, composición y diversidad de la población de peces: estudio de caso de Tema, Ghana

Ports offer economic progress to many coastal developing countries. In view of the economic importance, the rising demand for maritime benefits requires the expansion of existing ports. However, marine ecosystems may become vulnerable to negative impact from the construction of these maritime structures. Therefore, the aim of the study was to establish the impact of Tema port expansion on the diversity and population structure of fish species. Data were collected quarterly from June 2018 to November 2021 through trawling fishing activities off the coast of Greater Accra, Ghana, and subsequently analysed using Primer 6 software. Sampling locations along the coast of Greater Accra included Vernon Bank (VNB), Disposal area (DSA) and Offshore Sakumono (OSK). The increased and reduced number of species at VNB and DSA, respectively, could be alluded to dredging and disposal of dredged spoils. Diversity indices at OSK site was higher than those observed in disturbed areas due to the absence of impact in this control area. Thus, it is recommended to conduct further studies on the assemblage of invasive species that migrated to the VNB during dredging activities, since these species can have severe economic impact on fishing activities of artisanal fishermen, especially at the local level.Los puertos ofrecen progreso económico a muchos países costeros en desarrollo. En vista de la importancia económica, la creciente demanda de beneficios marítimos requiere la ampliación de los puertos existentes. Sin embargo, los ecosistemas marinos pueden volverse vulnerables al impacto negativo de la construcción de estas estructuras marítimas. Por lo tanto, el objetivo del estudio fue establecer el impacto de la expansión del puerto de Tema sobre la diversidad y estructura de la población de peces. Los datos se recopilaron trimestralmente desde junio de 2018 hasta noviembre de 2021 mediante actividades de pesca de arrastre fren-te a la costa del Gran Accra, Ghana. Los mismos se analizaron utilizando el software Primer 6. Los lugares de muestreo a lo largo de la costa del Gran Accra incluyeron Vernon Bank (VNB), Disposal area (DSA) y Offshore Sakumono (OSK). El mayor y menor número de especies en VNB y DSA, respectivamente, podría deberse al dragado y disposición de los escombros removidos. Los índices de diversidad en el sitio OSK fueron más altos que los observados en áreas perturbadas debido a la ausencia de impacto en esta área de control. Por lo tanto, se recomienda realizar más estudios sobre las asociaciones de especies invasoras que migraron al VNB durante las actividades de dragado, ya que estas especies pueden tener severos impactos económicos en la actividad pesquera de los pescadores artesanales, especialmente a nivel local

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study

Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world. Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231. Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001). Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication

Risk of heavy metal ingestion from the consumption of two commercially valuable species of fish from the fresh and coastal waters of Ghana.

The need to evaluate the human health safety of fishery resources remain urgent in the mist of the ever-increasing fear of heavy metal toxicity from the consumption of Ghana's fisheries resource, as a consequence of pollution from several anthropogenic activities including artisanal gold mining. Nevertheless, the bigeye grunt (Brachydeuterus auritus) and Bagrid catfish (Chrysichthys nigrodigitatus) remain commercially valuable fish species in West Africa and continue to attract high patronage.Forty-five specimens each of C. nigrodigitatus and B. auritus collected from the Weija Dam and the Tema Fishing Habour in Ghana, between June and September 2016, were analysed for seven heavy metals using Atomic Absorption Spectrometry.Lead and Cadmium were below detection in all samples while Cu was not detected in B. auritus. Levels of the remaining metals (mg kg-1) were below FAO/WHO maximum permissible limits in fish and occurred in the rank order Se (3.5) > Zn (2.34) > Cu (0.59) > As (0.37) > Hg (0.19) in C. nigrodigitatus and Se (2.97) > Zn (2.28) > Hg (0.31) > As (0.21) in B. auritus. Only As in C. nigrodigitatus recorded Estimated Weekly Intake (EWI) greater than FAO/WHO Provisional Tolerable Weekly Intake (PTWI). Also, As in C. nigrodigitatus and Hg in B. auritus had Targeted Hazard Quotient (THQ) greater than 1 for individuals consuming the fishes on daily basis and therefore, raising concerns. However, for both species of fish, cancer risk of As was 1 in 10,000,000,000 and modified Health Benefits values of Se (HBVSe) were positive indicating the health risks that might accompany Hg exposure would be negated. Since toxicity depends on the concentration and quantity of a pollutant consumed, safe maximum consumption rate of C. nigrodigitatus based on As concentrations was 0.21 mg per day and that of B. auritus was 0.058 mg per day for Hg. With an average of 0.227 kg fish per meal of an adult human, these translated into not more than 24 C. nigrodigitatus and nine (9) B. auritus meals in a month but because fish is consumed at 0.0685 kg per person per day in Ghana, these values respectively translates to 93 and 30 safe days of consumption per month.At the rate of 0.0685 kg fish per person per day that fish is consumed in Ghana, the consumption of the two species of fish in Ghana would essentially be of little or no consequence to consumers

Human health risk assessment parameters of heavy metals from the consumption of <i>Chrysichthys nigrodigitatus</i> and <i>Brachydeuterus auritus</i> respectively from the fresh and coastal waters of Ghana.

<p>Human health risk assessment parameters of heavy metals from the consumption of <i>Chrysichthys nigrodigitatus</i> and <i>Brachydeuterus auritus</i> respectively from the fresh and coastal waters of Ghana.</p

Trends in the concentration of heavy metals in the muscle tissues of <i>Brachydeuterus auritus</i> from the coastal waters of Ghana.

<p>Note: Pb, Cd and Cu were below detection limits in B. auritus. Also, pairwise comparison indicates concentration of all metals were significantly different except As and Hg (Kruskal-Wallis test with Fisher’s LSD post hoc, H_3,0.05 = 129.618, p < 0.05.</p

Comparison of heavy metals concentrations between the muscle tissues of <i>Chrysichthys nigrodigitatus</i> and <i>Brachydeuterus auritus</i> from the waters of Ghana.

<p>Note: <i>Mean ± SD with different letters in columns are significantly different (Mann–Whitney U test</i>, <i>p > 0</i>.<i>05)</i>.</p

Map of Ghana showing the Weija Dam and the Tema fishing harbour where fish specimens were collected.

<p>Map of Ghana showing the Weija Dam and the Tema fishing harbour where fish specimens were collected.</p

Frequency distribution of metal concentrations in the muscle tissues of <i>Chrysichthys nigrodigitatus</i> and <i>Brachydeuterus auritus</i> from the waters of Ghana.

<p>Note: Pb, Cd and Cu were excluded from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0194682#pone.0194682.g001" target="_blank">Fig 1</a> because Pb and Cd were below detection in all samples while 96% of the C. nigrodigitatus and 100% of the B. auritus samples had Cu levels below detections.</p