2,061 research outputs found
Adherence and Constancy in LIME-RS Explanations for Recommendation
Explainable Recommendation has attracted a lot of attention due to a renewed interest in explainable artificial intelligence. In
particular, post-hoc approaches have proved to be the most easily applicable ones to increasingly complex recommendation
models, which are then treated as black boxes. The most recent literature has shown that for post-hoc explanations based
on local surrogate models, there are problems related to the robustness of the approach itself. This consideration becomes
even more relevant in human-related tasks like recommendation. The explanation also has the arduous task of enhancing
increasingly relevant aspects of user experience such as transparency or trustworthiness. This paper aims to show how
the characteristics of a classical post-hoc model based on surrogates is strongly model-dependent and does not prove to be
accountable for the explanations generatedThe authors acknowledge partial support of PID2019-108965GB-I00, PONARS01_00876BIO-D,CasadelleTecnologie
mergenti della Cittàdi Matera, PONARS01_00821FLET4.0, PIAServiziLocali2.0,H2020Passapartout-Grantn. 101016956, PIAERP4.0,andIPZS-PRJ4_IA_NORMATIV
Effect of oral consumption of capsules containing Lactobacillus paracasei LPC-S01 on the vaginal microbiota of healthy adult women: a randomized, placebo-controlled, double-blind crossover study
Oral consumption of probiotics is practical and can be an effective solution to preserve vaginal eubiosis. Here, we studied the ability of orally administered Lactobacillus paracasei LPC-S01 (DSM 26760) to affect the composition of the vaginal microbiota and colonize the vaginal mucosa in nondiseased adult women. A total of 40 volunteers took oral probiotic (24 billion CFU) or placebo capsules daily for 4 weeks, and after a 4-week washout, they switched to placebo or probiotic capsules according to the crossover design. A total of 23 volunteers completed the study according to the protocol. Before and after capsule ingestion, vaginal swabs were collected for qPCR quantification to detect L. paracasei LPC-S01 and for 16S rRNA gene sequencing. Vaginal swabs were grouped according to their bacterial taxonomic structure into nine community state types (CSTs), four of which were dominated by lactobacilli. Lactobacillus paracasei LPC-S01 was detected in the vagina of two participants. Statistical modeling (including linear mixed-effects model analysis) demonstrated that daily intake of probiotic capsules reduced the relative abundance of Gardnerella spp. Quantitative PCR with Gardnerella vaginalis primers confirmed this result. Considering the pathogenic nature of G. vaginalis, these results suggest a potential positive effect of this probiotic capsule on the vaginal microbial ecosystem
Proton-proton elastic scattering at the LHC energy of {\surd} = 7 TeV
Proton-proton elastic scattering has been measured by the TOTEM experiment at
the CERN Large Hadron Collider at {\surd}s = 7 TeV in dedicated runs with the
Roman Pot detectors placed as close as seven times the transverse beam size
(sbeam) from the outgoing beams. After careful study of the accelerator optics
and the detector alignment, |t|, the square of four-momentum transferred in the
elastic scattering process, has been determined with an uncertainty of d t =
0.1GeV p|t|. In this letter, first results of the differential cross section
are presented covering a |t|-range from 0.36 to 2.5GeV2. The differential
cross-section in the range 0.36 < |t| < 0.47 GeV2 is described by an
exponential with a slope parameter B = (23.6{\pm}0.5stat {\pm}0.4syst)GeV-2,
followed by a significant diffractive minimum at |t| =
(0.53{\pm}0.01stat{\pm}0.01syst)GeV2. For |t|-values larger than ~ 1.5GeV2, the
cross-section exhibits a power law behaviour with an exponent of -7.8_\pm}
0.3stat{\pm}0.1syst. When compared to predictions based on the different
available models, the data show a strong discriminative power despite the small
t-range covered.Comment: 12pages, 5 figures, CERN preprin
Performance of the LHCb muon system with cosmic rays
The LHCb Muon system performance is presented using cosmic ray events
collected in 2009. These events allowed to test and optimize the detector
configuration before the LHC start. The space and time alignment and the
measurement of chamber efficiency, time resolution and cluster size are
described in detail. The results are in agreement with the expected detector
performance.Comment: Submitted to JINST and accepte
Performance of the LHCb muon system
The performance of the LHCb Muon system and its stability across the full
2010 data taking with LHC running at ps = 7 TeV energy is studied. The
optimization of the detector setting and the time calibration performed with
the first collisions delivered by LHC is described. Particle rates, measured
for the wide range of luminosities and beam operation conditions experienced
during the run, are compared with the values expected from simulation. The
space and time alignment of the detectors, chamber efficiency, time resolution
and cluster size are evaluated. The detector performance is found to be as
expected from specifications or better. Notably the overall efficiency is well
above the design requirementsComment: JINST_015P_1112 201
Measurement of the front-end dead-time of the LHCb muon detector and evaluation of its contribution to the muon detection inefficiency
A method is described which allows to deduce the dead-time of the front-end
electronics of the LHCb muon detector from a series of measurements performed
at different luminosities at a bunch-crossing rate of 20 MHz. The measured
values of the dead-time range from 70 ns to 100 ns. These results allow to
estimate the performance of the muon detector at the future bunch-crossing rate
of 40 MHz and at higher luminosity
Irradiation and SPS Beam Tests of the Alice1LHCb Pixel Chip
The Alice1LHCb front-end chip has been designed for the ALICE pixel and the LHCb RICH detectors. It is fabricated in a commercial 0.25 µm CMOS technology, with special design techniques to obtain radiation tolerance. The chip has been irradiated with low energy protons and heavy ions, to determine the cross-section for Single Event Upsets (SEU), and with X-rays to evaluate the sensitivity to total ionising dose. We report the results of those measurements. We also report preliminary results of measurements done with 150 GeV pions at the CERN SPS
A facility to Search for Hidden Particles (SHiP) at the CERN SPS
A new general purpose fixed target facility is proposed at the CERN SPS
accelerator which is aimed at exploring the domain of hidden particles and make
measurements with tau neutrinos. Hidden particles are predicted by a large
number of models beyond the Standard Model. The high intensity of the SPS
400~GeV beam allows probing a wide variety of models containing light
long-lived exotic particles with masses below (10)~GeV/c,
including very weakly interacting low-energy SUSY states. The experimental
programme of the proposed facility is capable of being extended in the future,
e.g. to include direct searches for Dark Matter and Lepton Flavour Violation.Comment: Technical Proposa
Evaluation of a large set of patients with Autoimmune Polyglandular Syndrome from a single reference centre in context of different classifications
Purpose: To characterize patients with APS and to propose a new approach for their follow-up. Query ID="Q1" Text="Please check the given names and familynames." Methods: Monocentric observational retrospective study enrolling patients referred to the Outpatients clinic of the Units of Endocrinology, Diabetology, Gastroenterology, Rheumatology and Clinical Immunology of our Hospital for Autoimmune diseases. Results: Among 9852 patients, 1174 (11.9%) [869 (73.9%) female] were diagnosed with APS. In 254 subjects, the diagnosis was made at first clinical evaluation (Group 1), all the other patients were diagnosed with a mean latency of 11.3 ± 10.6 years (Group 2). Group 1 and 2 were comparable for age at diagnosis (35.7 ± 16.3 vs. 40.4 ± 16.6 yrs, p =.698), but different in male/female ratio (81/173 vs 226/696, p =.019). In Group 2, 50% of patients developed the syndrome within 8 years of follow-up. A significant difference was found after subdividing the first clinical manifestation into the different outpatient clinic to which they referred (8.7 ± 8.0 vs. 13.4 ± 11.6 vs. 19.8 ± 8.7 vs. 7.4 ± 8.1 for endocrine, diabetic, rheumatologic, and gastroenterological diseases, respectively, p <.001). Conclusions: We described a large series of patients affected by APS according to splitters and lumpers. We propose a flowchart tailored for each specialist outpatient clinic taking care of the patients. Finally, we recommend regular reproductive system assessment due to the non-negligible risk of developing premature ovarian failure
Measurement of the cross-section and charge asymmetry of bosons produced in proton-proton collisions at TeV with the ATLAS detector
This paper presents measurements of the and cross-sections and the associated charge asymmetry as a
function of the absolute pseudorapidity of the decay muon. The data were
collected in proton--proton collisions at a centre-of-mass energy of 8 TeV with
the ATLAS experiment at the LHC and correspond to a total integrated luminosity
of 20.2~\mbox{fb^{-1}}. The precision of the cross-section measurements
varies between 0.8% to 1.5% as a function of the pseudorapidity, excluding the
1.9% uncertainty on the integrated luminosity. The charge asymmetry is measured
with an uncertainty between 0.002 and 0.003. The results are compared with
predictions based on next-to-next-to-leading-order calculations with various
parton distribution functions and have the sensitivity to discriminate between
them.Comment: 38 pages in total, author list starting page 22, 5 figures, 4 tables,
submitted to EPJC. All figures including auxiliary figures are available at
https://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/STDM-2017-13
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