8 research outputs found
Establishment of a three-dimensional in vitro model of air-blood barrier to assess the translocation of nanoparticles targeted to the lung
- Publication venue
- Publication date
- 15/06/2018
- Field of study
Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
- Author
- Aali Amirali
- Abbafati Cristiana
- Abbas Jaffar
- Abbasgholizadeh Rouzbeh
- Abbasi Madineh Akram
- Abbasian Mohammadreza
- Abd ElHafeez Samar
- Abd-Elsalam Sherief
- Abdelmasseh Michael
- Abdelwahab Ahmed
- Abdollahi Mohammad
- Abdoun Meriem
- Abdullahi Auwal
- Abdurehman Ame Mehadi
- Abebe Mesfin
- Abedi Aidin
- Abedi Armita
- Abegaz Tadesse M
- Abeldaño Zuñiga Roberto Ariel
- Abhilash E S
- Abiodun Olugbenga Olusola
- Aboagye Richard Gyan
- Abolhassani Hassan
- Abouzid Mohamed
- Abreu Lucas Guimarães
- Abrha Woldu Aberhe
- Abrigo Michael R M
- Abtahi Dariush
- Abu Rumeileh Samir
- Abu-Rmeileh Niveen ME
- Abu-Zaid Ahmed
- Aburuz Salahdein
- Acuna Juan Manuel
- Adair Tim
- Addo Isaac Yeboah
- Adebayo Oladimeji M
- Adegboye Oyelola A
- Adekanmbi Victor
- Aden Bashir
- Adepoju Abiola Victor
- Adetunji Charles Oluwaseun
- Adeyeoluwa Temitayo Esther
- Adeyomoye Olorunsola Israel
- Adha Rishan
- Adibi Amin
- Adikusuma Wirawan
- Adnani Qorinah Estiningtyas Sakilah
- Adra Saryia
- Afework Abel
- Afolabi Aanuoluwapo Adeyimika
- Afraz Ali
- Afyouni Shadi
- Afzal Saira
- Agasthi Pradyumna
- Aghamiri Shahin
- Agodi Antonella
- Agyemang-Duah Williams
- Ahinkorah Bright Opoku
- Ahmad Aqeel
- Ahmad Danish
- Ahmad Firdos
- Ahmad Muayyad M
- Ahmad Tauseef
- Ahmadi Keivan
- Ahmadzade Amir Mahmoud
- Ahmadzade Mohadese
- Ahmed Ayman
- Ahmed Haroon
- Ahmed Luai A
- Ahmed Muktar Beshir
- Ahmed Syed Anees
- Ajami Marjan
- Aji Budi
- Ajumobi Olufemi
- Akalu Gizachew Taddesse
- Akara Essona Matatom
- Akinosoglou Karolina
- Akkala Sreelatha
- Akyirem Samuel
- Al Hamad Hanadi
- Al Hasan Syed Mahfuz
- Al Homsi Ammar
- Al Qadire Mohammad
- AL-Ahdal Tareq Mohammed Ali
- Al-Aly Ziyad
- Al-amer Rasmieh Mustafa
- Al-Eyadhy Ayman
- Al-Gheethi Adel Ali Saeed
- Al-Hanawi Mohammed Khaled
- Al-Jumaily Adel
- Al-Marwani Sabah
- Al-Maweri Sadeq Ali Ali
- Al-Mekhlafi Hesham M
- Al-Sabah Salman Khalifah
- Al-Tawfiq Jaffar A
- Al-Worafi Yaser Mohammed
- Ala Moein
- Aladelusi Timothy Olukunle
- Alalalmeh Samer O
- Alam Khurshid
- Alam Manjurul
- Alam Zufishan
- Alanezi Fahad Mashhour
- Alanzi Turki M
- Albashtawy Mohammed
- AlBataineh Mohammad T
- Aldridge Robert W
- Alemi Sharifullah
- Alhabib Khalid F
- Alhalaiqa Fadwa Alhalaiqa Naji
- Ali Abid
- Ali Akhtar
- Ali Beriwan Abdulqadir
- Ali Hassam
- Ali Mohammed Usman
- Ali Rafat
- Ali Syed Shujait Shujait
- Ali Zahid
- Alian Samakkhah Shohreh
- Alicandro Gianfranco
- Alif Sheikh Mohammad
- Aligol Mohammad
- Alimi Rasoul
- Aliyi Ahmednur Adem
- Aljunid Syed Mohamed
- Almahmeed Wael
- Almazan Joseph Uy
- Almidani Omar
- Alomari Mahmoud A
- Alonso Nivaldo
- Alqahtani Jaber S
- Alqutaibi Ahmed Yaseen
- Altaf Awais
- Altirkawi Khalid A
- Alvi Farrukh Jawad
- Alwafi Hassan
- Aly Hany
- Alzoubi Karem H
- Amare Azmeraw T
- Ameyaw Edward Kwabena
- Amhare Abebe Feyissa
- Amin Tarek Tawfik
- Amindarolzarbi Alireza
- Aminian Dehkordi Javad
- Amiri Sohrab
- Amu Hubert
- Amugsi Dickson A
- Amzat Jimoh
- Ancuceanu Robert
- Anderlini Deanna
- Andrade Pedro Prata
- Andrei Catalina Liliana
- Andrei Tudorel
- Angappan Dhanalakshmi
- Anil Abhishek
- Anjum Afifa
- Antony Catherine M
- Antriyandarti Ernoiz
- Anuoluwa Iyadunni Adesola
- Anwar Sumadi Lukman
- Anyasodor Anayochukwu Edward
- Appiah Seth Christopher Yaw
- Aqeel Muhammad
- Arab-Zozani Morteza
- Arabloo Jalal
- Arabzadeh Bahri Razman
- Arafat Mosab
- Araújo Ana Margarida
- Aravkin Aleksandr Y
- Aremu Abdulfatai
- Ariffin Hany
- Aripov Timur
- Armocida Benedetta
- Arooj Mahwish
- Artamonov Anton A
- Artanti Kurnia Dwi
- Arulappan Judie
- Aruleba Idowu Thomas
- Aruleba Raphael Taiwo
- Arumugam Ashokan
- Asaad Malke
- Asgary Saeed
- Ashemo Mubarek Yesse
- Ashraf Muhammad
- Asika Marvellous O
- Athari Seyyed Shamsadin
- Atout Maha Moh'd Wahbi
- Atreya Alok
- Attia Sameh
- Aujayeb Avinash
- Avan Abolfazl
- Awotidebe Adedapo Wasiu
- Ayala Quintanilla Beatriz Paulina
- Ayanore Martin Amogre
- Ayele Getnet Melaku
- Ayuso-Mateos Jose L
- Ayyoubzadeh Seyed Mohammad
- Azadnajafabad Sina
- Azhar Gulrez Shah
- Aziz Shahkaar
- Azzam Ahmed Y
- Babashahi Mina
- Babu Abraham Samuel
- Badar Muhammad
- Badawi Alaa
- Badiye Ashish D
- Baghdadi Soroush
- Bagheri Nasser
- Bagherieh Sara
- Bah Sulaiman
- Bahadorikhalili Saeed
- Bai Jianjun
- Bai Ruhai
- Baker Jennifer L
- Bakkannavar Shankar M
- Bako Abdulaziz T
- Balakrishnan Senthilkumar
- Balogun Saliu A
- Baltatu Ovidiu Constantin
- Bam Kiran
- Banach Maciej
- Bandyopadhyay Soham
- Banik Biswajit
- Banik Palash Chandra
- Bansal Hansi
- Barati Shirin
- Barchitta Martina
- Bardhan Mainak
- Barker-Collo Suzanne Lyn
- Barone-Adesi Francesco
- Barqawi Hiba Jawdat
- Barr Ronald D
- Barrero Lope H
- Basharat Zarrin
- Bashir Asma'u I J
- Bashiru Hameed Akande
- Baskaran Pritish
- Basnyat Buddha
- Bassat Quique
- Basso João Diogo
- Basu Saurav
- Batra Kavita
- Batra Ravi
- Baune Bernhard T
- Bayati Mohsen
- Bayileyegn Nebiyou Simegnew
- Beaney Thomas
- Bedi Neeraj
- Begum Tahmina
- Behboudi Emad
- Behnoush Amir Hossein
- Beiranvand Maryam
- Bejarano Ramirez Diana Fernanda
- Belgaumi Uzma Iqbal
- Bell Michelle L
- Bello Aminu K
- Bello Muhammad Bashir
- Bello Olorunjuwon Omolaja
- Belo Luis
- Beloukas Apostolos
- Bendak Salaheddine
- Bennett Derrick A
- Bensenor Isabela M
- Benzian Habib
- Berezvai Zombor
- Berman Adam E
- Bermudez Amiel Nazer C
- Bettencourt Paulo J G
- Beyene Habtamu B
- Beyene Kebede A
- Bhagat Devidas S
- Bhagavathula Akshaya Srikanth
- Bhala Neeraj
- Bhalla Ashish
- Bhandari Dinesh
- Bhardwaj Nikha
- Bhardwaj Pankaj
- Bhardwaj Prarthna V
- Bhargava Ashish
- Bhaskar Sonu
- Bhat Vivek
- Bhatti Gurjit Kaur
- Bhatti Jasvinder Singh
- Bhatti Manpreet S
- Bhatti Rajbir
- Bhutta Zulfiqar A
- Bikbov Boris
- Binmadi Nada
- Bintoro Bagas Suryo
- Biondi Antonio
- Bisignano Catherine
- Bisulli Francesca
- Biswas Atanu
- Biswas Raaj Kishore
- Bitaraf Saeid
- Bjørge Tone
- Bleyer Archie
- Boampong Mary Sefa
- Bodolica Virginia
- Bodunrin Aadam Olalekan
- Bolarinwa Obasanjo Afolabi
- Bonakdar Hashemi Milad
- Bonny Aime
- Bora Basara Berrak
- Bora Kaustubh
- Borodo Safiya Bala
- Borschmann Rohan
- Botero Carvajal Alejandro
- Bouaoud Souad
- Boudalia Sofiane
- Boyko Edward J
- Bragazzi Nicola Luigi
- Braithwaite Dejana
- Brenner Hermann
- Britton Gabrielle
- Browne Annie J
- Brunoni Andre R
- Bulamu Norma B
- Bulto Lemma N
- Buonsenso Danilo
- Burkart Katrin
- Burns Richard A
- Burugina Nagaraja Sharath
- Busse Reinhard
- Bustanji Yasser
- Butt Zahid A
- Caetano dos Santos Florentino Luciano
- Cai Tianji
- Calina Daniela
- Campos Luciana Aparecida
- Campos-Nonato Ismael R
- Cao Chao
- Cardenas Carlos Alberto
- Carr Sinclair
- Carreras Giulia
- Carrero Juan J
- Carugno Andrea
- Carvalho Felix
- Carvalho Márcia
- Castaldelli-Maia Joao Mauricio
- Castañeda-Orjuela Carlos A
- Castelpietra Giulio
- Catalá-López Ferrán
- Catapano Alberico L
- Cattaruzza Maria Sofia
- Caye Arthur
- Cámera Luis Alberto
- Cárdenas Rosario
- Cederroth Christopher R
- Cembranel Francieli
- Cenderadewi Muthia
- Cercy Kelly M
- Cerin Ester
- Cevik Muge
- Chacón-Uscamaita Pamela R Uscamaita
- Chahine Yaacoub
- Chakraborty Chiranjib
- Chan Jeffrey Shi Kai
- Chang Chin-Kuo
- Charalampous Periklis
- Charan Jaykaran
- Chattu Vijay Kumar
- Chatzimavridou-Grigoriadou Victoria
- Chavula Malizgani Paul
- Cheema Huzaifa Ahmad
- Chen An-Tian
- Chen Haowei
- Chen Lingxiao
- Chen Meng Xuan
- Chen Simiao
- Cherbuin Nicolas
- Chew Derek S
- Chi Gerald
- Chirinos-Caceres Jesus Lorenzo
- Chitheer Abdulaal
- Cho So Mi Jemma
- Cho William C S
- Chong Bryan
- Chopra Hitesh
- Choudhary Rahul
- Chowdhury Rajiv
- Chu Dinh-Toi
- Chukwu Isaac Sunday
- Chung Eric
- Chung Eunice
- Chung Sheng-Chia
- Cini Karly I
- Clark Cain C T
- Coberly Kaleb
- Columbus Alyssa
- Comfort Haley
- Conde Joao
- Conti Sara
- Cortesi Paolo Angelo
- Costa Vera Marisa
- Cousin Ewerton
- Cowden Richard G
- Criqui Michael H
- Cruz-Martins Natália
- Culbreth Garland T
- Cullen Patricia
- Cunningham Matthew
- D'Amico Emanuele
- da Silva e Silva Daniel
- Dadana Sriharsha
- Dadras Omid
- Dai Zhaoli
- Dalal Koustuv
- Dalli Lachlan L
- Damiani Giovanni
- Daneshvar Sara
- Darwesh Aso Mohammad
- Das Jai K
- Das Saswati
- Dash Nihar Ranjan
- Dashti Mohsen
- Davis Weaver Nicole
- Davletov Kairat
- Dávila-Cervantes Claudio Alberto
- De Leo Diego
- Debele Aklilu Tamire
- Degenhardt Louisa
- Dehbandi Reza
- Deitesfeld Lee
- Delgado-Enciso Ivan
- Delgado-Ortiz Laura
- Demant Daniel
- Demessa Berecha Hundessa
- Demetriades Andreas K
- Deng Xinlei
- Denova-Gutiérrez Edgar
- Deribe Kebede
- Dervenis Nikolaos
- Des Jarlais Don C
- Desai Hardik Dineshbhai
- Desai Rupak
- Deuba Keshab
- Devanbu Vinoth Gnana Chellaiyan
- Dey Sourav
- Dhali Arkadeep
- Dhama Kuldeep
- Dhimal Mandira Lamichhane
- Dhimal Meghnath
- Dhingra Sameer
- Dias da Silva Diana
- Diaz Daniel
- Dima Adriana
- Ding Delaney D
- Dirac M Ashworth
- Dixit Abhinav
- Dixit Shilpi Gupta
- do Prado Camila Bruneli
- Do Thanh Chi
- Do Thao Huynh Phuong
- Dodangeh Masoud
- Dokova Klara Georgieva
- Dolecek Christiane
- Dorsey E Ray
- dos Santos Wendel Mombaque
- Doshi Rajkumar
- Doshmangir Leila
- Douiri Abdel
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- Driscoll Tim Robert
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- Dube John
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- Duraisamy Senbagam
- Durojaiye Oyewole Christopher
- Dutta Sulagna
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- Dziedzic Arkadiusz Marian
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- Ed-Dra Abdelaziz
- Edinur Hisham Atan
- Edvardsson David
- Edvardsson Kristina
- Efendi Defi
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- Eghdami Shayan
- Eikemo Terje Andreas
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- Ekpor Emmanuel
- Ekundayo Temitope Cyrus
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- El Morsi Doaa Abdel Wahab
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- Elemam Noha Mousaad
- Elgar Frank J
- Elgendy Islam Y
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- Elhadi Muhammed
- Elmeligy Omar Abdelsadek Abdou
- Elshaer Mohammed
- Elsohaby Ibrahim
- Emami Zeydi Amir
- Emamverdi Mehdi
- Emeto Theophilus I
- Engelbert Bain Luchuo
- Erkhembayar Ryenchindorj
- Eshetie Tesfahun C
- Eskandarieh Sharareh
- Espinosa-Montero Juan
- Estep Kara
- Etaee Farshid
- Eze Ugochukwu Anthony
- Fabin Natalia
- Fadaka Adewale Oluwaseun
- Fagbamigbe Adeniyi Francis
- Fahimi Saman
- Falzone Luca
- Farinha Carla Sofia e Sá
- Faris MoezAlIslam Ezzat Mahmoud
- Farjoud Kouhanjani Mohsen
- Faro Andre
- Farrokhpour Hossein
- Fatehizadeh Ali
- Fattahi Hamed
- Fauk Nelsensius Klau
- Fazeli Pooria
- Feigin Valery L
- Fekadu Ginenus
- Fereshtehnejad Seyed-Mohammad
- Feroze Abdullah Hamid
- Ferrante Daniela
- Ferrara Pietro
- Ferreira Nuno
- Fetensa Getahun
- Filip Irina
- Fischer Florian
- Flavel Joanne
- Flaxman Abraham D
- Flor Luisa S
- Florin Bobirca Teodor
- Folayan Morenike Oluwatoyin
- Foley Kristen Marie
- Fomenkov Artem Alekseevich
- Force Lisa M
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- Foroutan Behzad
- Foschi Matteo
- Francis Kate Louise
- Franklin Richard Charles
- Freitas Alberto
- Friedman Joseph
- Friedman Sara D
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- Fuller John E
- Gaal Peter Andras
- Gadanya Muktar A
- Gaihre Santosh
- Gaipov Abduzhappar
- Gakidou Emmanuela
- Galali Yaseen
- Galehdar Nasrin
- Gallus Silvano
- Gan Quan
- Gandhi Aravind P
- Ganesan Balasankar
- Garg Jalaj
- Gau Shuo-Yan
- Gautam Prem
- Gautam Rupesh K
- Gazzelloni Federica
- Gebregergis Miglas W
- Gebrehiwot Mesfin
- Gebremariam Tesfay Brhane
- Gerema Urge
- Getachew Motuma Erena
- Getachew Tamirat
- Gething Peter W
- Ghafourifard Mansour
- Ghahramani Sulmaz
- Ghailan Khalid Yaser
- Ghajar Alireza
- Ghanbarnia Mohammad Javad
- Ghasemi MohammadReza
- Ghasemzadeh Afsaneh
- Ghassemi Fariba
- Ghazy Ramy Mohamed
- Ghimire Sailaja
- Gholamian Asadollah
- Gholamrezanezhad Ali
- Ghorbani Vajargah Pooyan
- Ghozali Ghozali
- Ghozy Sherief
- Ghuge Arun Digambarrao
- Gialluisi Alessandro
- Gibson Ruth Margaret
- Gil Artyom Urievich
- Gill Paramjit Singh
- Gill Tiffany K
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- Ginindza Themba G
- Girmay Alem
- Glasbey James C
- Gnedovskaya Elena V
- Goel Amit
- Goldust Mohamad
- Golechha Mahaveer
- Goleij Pouya
- Golestanfar Arefeh
- Golinelli Davide
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- Goudarzi Houman
- Goudarzian Amir Hossein
- Goyal Anmol
- Göbölös Laszlo
- Greenhalgh Scott
- Grivna Michal
- Guarducci Giovanni
- Gubari Mohammed Ibrahim Mohialdeen
- Gudeta Mesay Dechasa
- Guha Avirup
- Guicciardi Stefano
- Gunawardane Damitha Asanga
- Gunturu Sasidhar
- Guo Cui
- Gupta Anish Kumar
- Gupta Bhawna
- Gupta Indarchand Ratanlal
- Gupta Rajat Das
- Gupta Sapna
- Gupta Veer Bala
- Gupta Vijai Kumar
- Gupta Vivek Kumar
- Gutiérrez Reyna Alma
- Habibzadeh Farrokh
- Habibzadeh Parham
- Hachinski Vladimir
- Haddadi Mohammad
- Haddadi Rasool
- Haep Nils
- Hajj Ali Adel
- Halboub Esam S
- Halim Sobia Ahsan
- Hall Brian J
- Haller Sebastian
- Halwani Rabih
- Hamadeh Randah R
- Hamagharib Abdullah Kanaan
- Hamidi Samer
- Hamiduzzaman Mohammad
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- Hannan Md Abdul
- Haque Md Nuruzzaman
- Harapan Harapan
- Haro Josep Maria
- Hasaballah Ahmed I
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- Hasan M Tasdik
- Hasani Hamidreza
- Hasanian Mohammad
- Hasanpour- Dehkordi Ali
- Hassan Abbas M
- Hassan Amr
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- Hassanipour Soheil
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- Hegazi Omar E
- Heidari Golnaz
- Heidari Mohammad
- Heidari-Foroozan Mahsa
- Heidari-Soureshjani Reza
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- Hesami Hamed
- Hettiarachchi Dineshani
- Heyi Demisu Zenbaba
- Hezam Kamal
- Hiraike Yuta
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- Holla Ramesh
- Horita Nobuyuki
- Hossain Md Belal
- Hossain Md Mahbub
- Hossain Sahadat
- Hosseini Mohammad-Salar
- Hosseinzadeh Hassan
- Hosseinzadeh Mehdi
- Hostiuc Mihaela
- Hostiuc Sorin
- Hsairi Mohamed
- Hsieh Vivian Chia-rong
- Hu Chengxi
- Huang Junjie
- Huda Md Nazmul
- Hugo Fernando N
- Hultström Michael
- Hussain Javid
- Hussain Salman
- Hussein Nawfal R
- Huy Le Duc
- Huynh Hong-Han
- Hwang Bing-Fang
- Ibitoye Segun Emmanuel
- Idowu Oluwatope Olaniyi
- Ijo Desta
- Ikuta Kevin S
- Ilaghi Mehran
- Ilesanmi Olayinka Stephen
- Ilic Irena M
- Ilic Milena D
- Immurana Mustapha
- Inbaraj Leeberk Raja
- Iradukunda Arnaud
- Iravanpour Farideh
- Iregbu Kenneth Chukwuemeka
- Islam Md Rabiul
- Islam Mohammad Mainul
- Islam Sheikh Mohammed Shariful
- Islami Farhad
- Ismail Nahlah Elkudssiah
- Isola Gaetano
- Iwagami Masao
- Iwu Chidozie C D
- Iwu-Jaja Chinwe Juliana
- Iyer Mahalaxmi
- J Linda Merin
- Jaafari Jalil
- Jacob Louis
- Jacobsen Kathryn H
- Jadidi-Niaragh Farhad
- Jafarinia Morteza
- Jaggi Khushleen
- Jahankhani Kasra
- Jahanmehr Nader
- Jahrami Haitham
- Jain Akhil
- Jain Nityanand
- Jairoun Ammar Abdulrahman
- Jakovljevic Mihajlo
- Jalilzadeh Yengejeh Reza
- Jamshidi Elham
- Jani Chinmay T
- Janko Mark M
- Jatau Abubakar Ibrahim
- Jayapal Sathish Kumar
- Jayaram Shubha
- Jeganathan Jayakumar
- Jema Alelign Tasew
- Jemere Digisie Mequanint
- Jeong Wonjeong
- Jha Anil K
- Jha Ravi Prakash
- Ji John S
- Jiang Heng
- Jin Yingzhao
- Jin Yinzi
- Johnson Olatunji
- Jomehzadeh Nabi
- Jones Darwin Phan
- Joo Tamas
- Joseph Abel
- Joseph Nitin
- Joshua Charity Ehimwenma
- Jozwiak Jacek Jerzy
- Jürisson Mikk
- Kaambwa Billingsley
- Kabir Ali
- Kabir Hannaneh
- Kabir Zubair
- Kadashetti Vidya
- Kahe Farima
- Kakodkar Pradnya Vishal
- Kalani Rizwan
- Kalankesh Leila R
- Kaliyadan Feroze
- Kalra Sanjay
- Kamath Ashwin
- Kamireddy Arun
- Kanagasabai Thanigaivelan
- Kandel Himal
- Kanmiki Edmund Wedam
- Kanmodi Kehinde Kazeem
- Kantar Rami S
- Kapoor Neeti
- Karajizadeh Mehrdad
- Karami Matin Behzad
- Karanth Shama D
- Karaye Ibraheem M
- Karim Asima
- Karimi Behnagh Arman
- Karimi Hanie
- Karimi Salah Eddin
- Karkhah Samad
- Karna Ajit K
- Kashoo Faizan Zaffar
- Kasraei Hengameh
- Kassaw Nigussie Assefa
- Kassebaum Nicholas J
- Kassel Molly B
- Katamreddy Adarsh
- Katikireddi Srinivasa Vittal
- Katoto Patrick DMC
- Kauppila Joonas H
- Kaur Navjot
- Kaydi Neda
- Kayibanda Jeanne Françoise
- Kayode Gbenga A
- Kazemi Foad
- Kazemian Sina
- Kazeminia sara
- Keikavoosi-Arani Leila
- Keller Cathleen
- Kempen John H
- Kerr Jessica A
- Kesse-Guyot Emmanuelle
- Keykhaei Mohammad
- Khadembashiri Mohamad Mehdi
- Khadembashiri Mohammad Amin
- Khafaie Morteza Abdullatif
- Khajuria Himanshu
- Khalafi Mohammad
- Khalaji Amirmohammad
- Khalid Nauman
- Khalil Ibrahim A
- Khamesipour Faham
- Khan suheb Mahammed Ziauddin
- Khan Asaduzzaman
- Khan Gulfaraz
- Khan Ikramullah
- Khan Imteyaz A
- Khan Maseer
- Khan Moien AB
- Khan Taimoor
- Khanmohammadi Shaghayegh
- Khatab Khaled
- Khatami Fatemeh
- Khavandegar Armin
- Khayat Kashani Hamid Reza
- Kheirallah Khalid A
- Khidri Feriha Fatima
- Khodadoust Elaheh
- Khormali Moein
- Khosrowjerdi Mahmood
- Khubchandani Jagdish
- Khusun Helda
- Kifle Zemene Demelash
- Kim Grace
- Kim Jihee
- Kimokoti Ruth W
- Kinzel Kasey E
- Kiross Girmay Tsegay
- Kisa Adnan
- Kisa Sezer
- Kiss Juniper Boroka
- Kivimäki Mika
- Klu Desmond
- Knudsen Ann Kristin Skrindo
- Kolahi Ali-Asghar
- Kompani Farzad
- Koren Gerbrand
- Kosen Soewarta
- Kostev Karel
- Kotnis Ashwin Laxmikant
- Koul Parvaiz A
- Koulmane Laxminarayana Sindhura Lakshmi
- Koyanagi Ai
- Kravchenko Michael A
- Krishan Kewal
- Krishna Hare
- Krishnamoorthy Vijay
- Krishnamoorthy Yuvaraj
- Krohn Kris J
- Kuate Defo Barthelemy
- Kubeisy Connor M
- Kucuk Bicer Burcu
- Kuddus Md Abdul
- Kuddus Mohammed
- Kuitunen Ilari
- Kujan Omar
- Kulimbet Mukhtar
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- Zandi Milad
- Zandieh Ghazal G Z
- Zanghì Aurora
- Zare Iman
- Zastrozhin Mikhail Sergeevich
- Zeariya Mohammed G M
- Zeng Youjie
- Zhai Chunxia
- Zhang Chen
- Zhang Haijun
- Zhang Hongwei
- Zhang Yunquan
- Zhang Zhaofeng
- Zhang Zhenyu
- Zhao Hanqing
- Zhao Yang
- Zhao Yong
- Zheng Peng
- Zhong Chenwen
- Zhou Juexiao
- Zhu Bin
- Zhu Zhaohua
- Ziaeefar Pardis
- Zielińska Magdalena
- Zou Zhiyong
- Zumla Alimuddin
- Zweck Elric
- Zyoud Samer H
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides new demographic estimates for 204 countries and territories and 811 additional subnational locations from 1950 to 2021, with a particular emphasis on changes in mortality and life expectancy that occurred during the 2020–21 COVID-19 pandemic period. Methods: 22 223 data sources from vital registration, sample registration, surveys, censuses, and other sources were used to estimate mortality, with a subset of these sources used exclusively to estimate excess mortality due to the COVID-19 pandemic. 2026 data sources were used for population estimation. Additional sources were used to estimate migration; the effects of the HIV epidemic; and demographic discontinuities due to conflicts, famines, natural disasters, and pandemics, which are used as inputs for estimating mortality and population. Spatiotemporal Gaussian process regression (ST-GPR) was used to generate under-5 mortality rates, which synthesised 30 763 location-years of vital registration and sample registration data, 1365 surveys and censuses, and 80 other sources. ST-GPR was also used to estimate adult mortality (between ages 15 and 59 years) based on information from 31 642 location-years of vital registration and sample registration data, 355 surveys and censuses, and 24 other sources. Estimates of child and adult mortality rates were then used to generate life tables with a relational model life table system. For countries with large HIV epidemics, life tables were adjusted using independent estimates of HIV-specific mortality generated via an epidemiological analysis of HIV prevalence surveys, antenatal clinic serosurveillance, and other data sources. Excess mortality due to the COVID-19 pandemic in 2020 and 2021 was determined by subtracting observed all-cause mortality (adjusted for late registration and mortality anomalies) from the mortality expected in the absence of the pandemic. Expected mortality was calculated based on historical trends using an ensemble of models. In location-years where all-cause mortality data were unavailable, we estimated excess mortality rates using a regression model with covariates pertaining to the pandemic. Population size was computed using a Bayesian hierarchical cohort component model. Life expectancy was calculated using age-specific mortality rates and standard demographic methods. Uncertainty intervals (UIs) were calculated for every metric using the 25th and 975th ordered values from a 1000-draw posterior distribution. Findings: Global all-cause mortality followed two distinct patterns over the study period: age-standardised mortality rates declined between 1950 and 2019 (a 62·8% [95% UI 60·5–65·1] decline), and increased during the COVID-19 pandemic period (2020–21; 5·1% [0·9–9·6] increase). In contrast with the overall reverse in mortality trends during the pandemic period, child mortality continued to decline, with 4·66 million (3·98–5·50) global deaths in children younger than 5 years in 2021 compared with 5·21 million (4·50–6·01) in 2019. An estimated 131 million (126–137) people died globally from all causes in 2020 and 2021 combined, of which 15·9 million (14·7–17·2) were due to the COVID-19 pandemic (measured by excess mortality, which includes deaths directly due to SARS-CoV-2 infection and those indirectly due to other social, economic, or behavioural changes associated with the pandemic). Excess mortality rates exceeded 150 deaths per 100 000 population during at least one year of the pandemic in 80 countries and territories, whereas 20 nations had a negative excess mortality rate in 2020 or 2021, indicating that all-cause mortality in these countries was lower during the pandemic than expected based on historical trends. Between 1950 and 2021, global life expectancy at birth increased by 22·7 years (20·8–24·8), from 49·0 years (46·7–51·3) to 71·7 years (70·9–72·5). Global life expectancy at birth declined by 1·6 years (1·0–2·2) between 2019 and 2021, reversing historical trends. An increase in life expectancy was only observed in 32 (15·7%) of 204 countries and territories between 2019 and 2021. The global population reached 7·89 billion (7·67–8·13) people in 2021, by which time 56 of 204 countries and territories had peaked and subsequently populations have declined. The largest proportion of population growth between 2020 and 2021 was in sub-Saharan Africa (39·5% [28·4–52·7]) and south Asia (26·3% [9·0–44·7]). From 2000 to 2021, the ratio of the population aged 65 years and older to the population aged younger than 15 years increased in 188 (92·2%) of 204 nations. Interpretation: Global adult mortality rates markedly increased during the COVID-19 pandemic in 2020 and 2021, reversing past decreasing trends, while child mortality rates continued to decline, albeit more slowly than in earlier years. Although COVID-19 had a substantial impact on many demographic indicators during the first 2 years of the pandemic, overall global health progress over the 72 years evaluated has been profound, with considerable improvements in mortality and life expectancy. Additionally, we observed a deceleration of global population growth since 2017, despite steady or increasing growth in lower-income countries, combined with a continued global shift of population age structures towards older ages. These demographic changes will likely present future challenges to health systems, economies, and societies. The comprehensive demographic estimates reported here will enable researchers, policy makers, health practitioners, and other key stakeholders to better understand and address the profound changes that have occurred in the global health landscape following the first 2 years of the COVID-19 pandemic, and longer-term trends beyond the pandemic
Characterisation of microbial attack on archaeological bone
- Author
- Abrantes Ana M
- Abreu Ana C
- Abreu Renato
- Abreu Renato
- Abreu Wilson
- Acedo Guadalupe
- Afonso Carlos
- Afreixo Vera
- Agudelo Mª E
- Alarcão Violeta
- Albuquerque Carlos
- Albuquerque Carlos
- Albuquerque Carlos
- Alencar Liana
- Alferes Valentim R
- Aliseda Isabel R
- Almada Lívia F
- Almeia António
- Almeida Ana
- Almeida Ana
- Almeida António
- Almeida António
- Almeida Armando
- Almeida Armando
- Almeida Fabrícia M
- Almeida Henrique
- Almeida Henrique A
- Almeida Henrique A
- Almeida Inês
- Almeida Jorge
- Almeida José P
- Almeida Maria
- Almeida Pedro
- Almeida Sidalina
- Alvarenga-Martins Nathália
- Alves B.
- Alves B.
- Alves Celeste
- Alves Dina
- Alves Gilberto
- Alves Helder
- Alves Josiane
- Alves José M
- Alves Juliana
- Alves Júlia M
- Alves Nuno
- Alves Nuno
- Alves Samuel
- Amado Diogo
- Amado João
- Amado Sandra
- Amaral Ana P
- Amaral Ana P
- Amaral Odete
- Amaral Odete
- Amaral Odete
- Amaral Odete
- Amaral Odete
- Ambrósio Sara
- Amendoeira José
- Amorim Ana
- Amorim Ana P
- Amorim Helena
- Andrade Diogo
- Andrade Isabel
- Andrade Isabel
- Andrade Isabel
- Andrade Isabel
- Andrade Isabel
- Andrade Isabel
- Andrade J. A
- Andrade Karizia V
- Andrade Renato
- Andrade Renato
- Andrade Susana
- Antunes Ana
- Antunes Ana
- Antunes Cristina
- Antunes Lígia
- Antunes Sandra
- Antunes Sandra
- Aparício Graça
- Aparício Graça
- Aparício José
- Apolinário-Hagen Jennifer
- Apolinário-Hagen Jennifer
- Aquino Caroline Q
- Aquino Caroline Q
- Aquino Priscila S
- Aquino Priscila S
- Araujo André R
- Araújo Beatriz
- Araújo Elsa
- Araújo Lia
- Araújo Odete
- Araújo Odete
- Araújo Patrícia
- Araújo Patrícia
- Araújo Patrícia
- Armas-Gonzalez Yadira
- Arreguy-Sena Cristina
- Arreguy-Sena Cristina
- Ascenso Rita T
- Ascenso Rita T
- Assunção Victor
- Augusto Cláudia
- Avelelas Francisco
- Ayoub Rodrigo
- Azeredo Zaida
- Azeredo Zaida
- Azeredo Zaida
- Azeredo Zaida
- Azevedo Julieta
- Azevedo Julieta
- Azevedo Marcelo
- Azevedo Maria H
- Azevedo Mª H
- Azevedo Tatiana
- Azzalis L.
- Baffour Gabriel
- Baffour Gabriel
- Bairros Keila
- Baixinho Cristina L
- Bajo Roberto
- Baltazar Ana L
- Barbeiro Ana P
- Barbosa Flávio
- Barbosa Tiago
- Barreira Eduarda
- Barreiros Luísa
- Barros Luísa
- Barros Luísa
- Barros Teresa
- Barroso Isabel
- Barroso Isabel
- Barroso Isabel
- Barroso João
- Basto Marta L
- Basto Marta L
- Basto Marta L
- Bastos Fernanda
- Bastos Fernanda
- Batalha Joana
- Batista Marco
- Batista Marco
- Batista Marco
- Batista Rita
- Baylina Pilar
- Becerra Isabel A
- Bellém Fernando
- Bellém Fernando
- Belo Pedro
- Benevides Joana
- Benevides Joana
- Bento Elisabete
- Bento Elisabete
- Bento Sandrina
- Bento Teresa
- Bergland Astrid
- Bernardes Lúcia G
- Bernardes Tiago
- Bernardo Helena
- Bexiga Filipa
- Bianchini Bruna
- Bizarro Carla
- Björklund Anita
- Blanco Valeriana G
- Boavida José
- Bonfim Luís
- Bordin Ronaldo
- Bordin Ronaldo
- Bordini Magali
- Borges Raphaelle
- Botelho Mª F
- Braga Fátima
- Braga Luciene
- Braga Luciene M
- Braga Luciene M
- Braga Margarida
- Branco Marco
- Brandão Daniela
- Brandão Daniela
- Brandão Frederico
- Brandão Piedade
- Brandão Teresa
- Bravo Rafael
- Bravo Rafael
- Breda São J
- Brito Alice
- Brito António
- Brito Irma
- Brito Luísa S
- Brito Nuno
- Brooks Dina
- Brunhoso Germana
- Brás Carina
- Brás Manuel
- Brêda Mª S J
- Bye Asta
- Caballero Francisco P
- Caballero Francisco P
- Caballero Francisco P
- Cabral Cremilde
- Cabral Gil
- Cabral Isabel
- Cabral Joana
- Cabral Lídia
- Cabral Priscila P
- Cabrita José
- Caceiro Elisa F
- Cadorio Inês
- Caeiro Patrícia
- Caldeira Suzana N
- Calha António
- Calha António
- Calvo Cristina
- Calvo Mª C
- Camarinha Luís
- Camarinha Luís
- Camarneiro Ana
- Camarneiro Ana
- Caminha Madson
- Campi Liliana
- Campofiorito C.
- Campos Maria
- Campos Maria
- Campos Mariana
- Campos Mª J
- Capelas Sylvie
- Cardoso Américo
- Cardoso Andreia
- Cardoso Ilda
- Cardoso Margarida
- Cardoso Mário E
- Cardoso Sara
- Cardoso Susana
- Carecho Nélio
- Carmen Barriga
- Carmo A.
- Carmo Bruno M
- Carneiro Juliana
- Carneiro Lara
- Carneiro Lara
- Carneiro M. A
- CaroMinghelli Eulália
- Carreira Diana
- Carreiras Diogo
- Carrão Luís
- Carvalhais Maribel
- Carvalhais Maribel
- Carvalho Amâncio
- Carvalho António
- Carvalho Carla
- Carvalho Carla
- Carvalho Carla
- Carvalho Carla
- Carvalho Carla
- Carvalho Carla
- Carvalho Célia B
- Carvalho Célia B
- Carvalho Célia B
- Carvalho Daniel
- Carvalho Daniel
- Carvalho Daniel
- Carvalho Daniel
- Carvalho Daniel
- Carvalho Francisco L
- Carvalho Inês
- Carvalho Joana
- Carvalho Lisiane L
- Carvalho Lisiane L
- Carvalho Lucinda
- Carvalho Nelma
- Carvalho Rosa
- Carvalho Rui
- Carvalho Sara
- Carvalho Sérgio
- Carvalho Teresa
- Carvalho Teresa
- Carvalho Tiago
- Carvalho Yara M
- Casalta-Lopes João
- Casas-Novas Mónica
- Caseiro Armando
- Caseiro Armando
- Caseiro Armando
- Caseiro Armando
- Caseiro Armando
- Casimiro Ana P
- Castilho Amélia
- Castilho Amélia
- Castilho Amélia
- Castilho Amélia
- Castilho Paula
- Castro Conceição
- Castro Régia B
- Castuera Ruth J
- Catarino Elisabete
- Catarino Helena
- Catarino Helena
- Catarino Helena
- Catarino Helena
- Catela David
- Cavalheiro Luís
- Cavalheiro Luís
- Certo Ana
- Cervato-Mancuso Ana M
- Cezanne Catarina
- Charepe Zaida
- Charepe Zaida
- Cheio Mónica
- Chen Gang
- Chung Wu F
- Clara João G
- Coelho Alexandre
- Coelho André
- Coelho Carina
- Coelho Elza S
- Coelho Inês
- Coelho Inês
- Coelho Luís
- Coelho Luís
- Coelho P.
- Coelho Patrícia
- Coelho Patrícia
- Colaço Armanda
- Colaço Armanda
- Colaço Diogo
- Collado-Mateo Daniel
- Collado-Mateo Daniel
- Combadão Jaime
- Conceição Milena A
- Conde Jorge
- Cordeiro Eugénio
- Cordeiro Marina
- Cordeiro Marina
- Cordeiro Marina
- Cordeiro Marina
- Cordeiro Marina
- Cordeiro Marina
- Cordeiro Raul
- Correia André
- Correia Jony
- Correia Telma
- Costa Ana R
- Costa André
- Costa Cláudia
- Costa Diana
- Costa Diana
- Costa Emília
- Costa Joyce O
- Costa Joyce O
- Costa Pablo O
- Costa Ricardo
- Costa Rui
- Costa Tânia
- Costa Tânia
- Costa Vanessa
- Coucelo Tiago
- Coutinho André P
- Coutinho Paula
- Couto Cristina
- Couto Diana
- Couto Margarida
- Couto Margarida
- Cova Marco P
- Cruz Agostinho
- Cruz Agostinho
- Cruz Agostinho
- Cruz Agostinho
- Cruz Agostinho
- Cruz Agostinho
- Cruz Bárbara
- Cruz Graça
- Cruz Inês
- Cruz Inês
- Cruz Joana
- Cruz Joana
- Cruz João
- Cruz Pedro
- Cruz Rui
- Cruz Rui
- Cruz Rui
- Cruz Susana
- Cruz x
- Cunha Fátima
- Cunha Madalena
- Cunha Madalena
- Cunha Madalena
- Cunha Madalena
- Cunha Madalena
- Cunha Marina
- Cunha Marina
- Cunha Marina
- Cunha Marina
- Cunha Marina
- Cunha Marina
- Cunha Marina
- Cunha Marina
- Cunha Marina
- Cândido Anabela
- César Ana F
- Da Motta Carolina
- Da Motta Carolina
- Da Motta Carolina
- Daniel Fernanda
- Dantas Estélio
- Deodato Sérgio
- Desouzart Gustavo
- Dias Alberto P
- Dias António
- Dias Hélia
- Dias Sara S
- Dias Sara S
- Dias Sara S
- Dias Tiago
- Dinis Alexandra
- Dinis Alexandra
- Dixe Anjos
- Dixe Anjos
- Dixe Anjos
- Dixe Maria
- Dixe Maria D A
- Dixe Maria D A
- Dixe Mª A
- Dixe Mª A
- Dixe Mª A
- Dixe Mª A
- Dixe Mª A
- Dixe Mª A
- Domingos Joana
- Domingos Samuel
- Domingues Cátia
- Domingues Gabriela
- Domingues J. N
- Dreyer Laysa C
- Duarte Catarina
- Duarte Diana
- Duarte Diana
- Duarte Hugo
- Duarte Hugo
- Duarte João
- Duarte João
- Duarte João
- Duarte Mafalda
- Duarte Nuno
- Duarte Soraia
- Duarte Soraia
- Escanciano Susana R
- Escoval Ana
- Espada Mário
- Esteves Mª R
- Estevez Gustavo L
- Estrela Jéssica
- Evangelista Diana
- Faria Luís
- Faria Luís
- Faria Melissa
- Faria Paula
- Faria Paula
- Faustino António
- Faustino António
- Faustino António
- Fernandes Adília
- Fernandes Ana R
- Fernandes Andreia
- Fernandes Beatriz
- Fernandes Helder M
- Fernandes Jorge C
- Fernandes Morgana C
- Fernandes Patrícia
- Fernandes Patrícia
- Fernandes Paula
- Fernandes Paula O
- Fernandes Paula O
- Fernandes Renato
- Fernandes Rosina
- Fernandes Rosina
- Fernandes Rosina
- Fernandes Telma
- Fernandez Mª J L
- Ferraz Maira
- Ferraz Vera
- Ferreira Ana
- Ferreira Ana
- Ferreira Ana
- Ferreira Ana
- Ferreira António
- Ferreira António
- Ferreira Carlos
- Ferreira Cláudia
- Ferreira Cláudia
- Ferreira Cláudia
- Ferreira Cláudia
- Ferreira Dora
- Ferreira Eduardo
- Ferreira Eduardo
- Ferreira Irina
- Ferreira José
- Ferreira José
- Ferreira José P
- Ferreira Lino
- Ferreira Manuela
- Ferreira Manuela
- Ferreira Manuela
- Ferreira Manuela
- Ferreira Margarida
- Ferreira Margarida
- Ferreira Margarida
- Ferreira Margarida
- Ferreira Nelson
- Ferreira P.
- Ferreira Paulo P
- Ferreira Paulo P
- Ferreira Paulo P
- Ferreira Paulo P
- Ferreira Pedro
- Ferreira Pedro
- Ferreira Pedro
- Ferreira Pedro
- Ferreira Pedro
- Ferreira Pedro
- Ferreira Pedro L
- Ferreira Regina
- Ferrito Cândida
- Ferro-Lebres Vera
- Festas Clarinda
- Figueiredo Amélia
- Figueiredo Ana G
- Figueiredo Daniela
- Figueiredo J.
- Figueiredo João
- Figueiredo João P
- Figueiredo João P
- Figueiredo João P
- Figueiredo Mª C
- Figueiredo Mª H
- Figueiredo Mª H
- Figueiredo Paulo
- Filho Braulio L
- Filho João G
- Filho João G
- Filho João G
- Filipe Vítor
- Fiorin Bruno H
- Fleig Tânia C
- Fleig Tânia C
- Fonseca Ana R
- Fonseca F.
- Fonseca F.
- Fonseca Virgínia
- Fonseca Virgínia
- Fonseca-Pinto Rui
- Fonseca-Pinto Rui
- Fonseca-Pinto Rui
- Fonseca-Pinto Rui
- Fontana Karine C
- Fontes-Ribeiro Carlos
- Forte Henriqueta D
- Fotschl Ulrike
- Frade João G
- Frade João G
- Frade João G
- Francisco Irene
- Franco Débora
- Franco-Borges Graciete
- Freire Ana
- Freitas Alberto
- Freitas Gregório
- Freitas Gregório
- Freitas João
- Freitas Kátia
- Freitas Maria
- Freitas Otília
- Freitas Otília
- Freitas Vívien A
- Frigo Leticia
- Froemming Miriam B
- Fuentes-Broto Lorena
- Furtado Alessandra S
- Furtado G.
- Furtado Guilherme
- Furtado Guilherme
- Furtado Guilherme E
- G.Silva Anne
- Gabriel António
- Gabriel António
- Gabriel António
- Gabriel António
- Gabriel António
- Gabriel Joaquim
- Gabriel Joaquim
- Galhardo Ana
- Galhardo Ana
- Galhardo Ana
- Galhardo Ana
- Galvão Ana
- Galvão Ana
- Galvão Ana
- Galvão Sofia
- Gama Ester
- Gama João
- Ganho-Ávila Ana
- Garcia Ana P
- Garcia Inês
- Garcia Teresa
- Garcia-Gordillo Miguel A
- Garcia-Gordillo Miguel A
- Garrido António
- Gaspar Filomena
- Gaspar Filomena
- Gaudêncio Iris
- Gehrke F.
- Gehrke F.
- Gisin Stefan
- Glória Margarida
- Gomes Ana A
- Gomes Ana A
- Gomes Antônio T
- Gomes Catarina
- Gomes Fernando
- Gomes José
- Gomes José C
- Gomes José H
- Gomes José H
- Gomes José H
- Gomes João
- Gomes João
- Gomes João
- Gomes João
- Gomes João
- Gomes Lisa
- Gomes Maria
- Gomes Mª J
- Gomes Pedro
- Gomes Sofia
- Gomez Inmaculada R
- Gonzalez Estefania P
- González Jesús A
- Gonçalves Amadeu
- Gonçalves Ana
- Gonçalves Ana
- Gonçalves Ana C
- Gonçalves Guilherme
- Gonçalves Liliana
- Gonçalves Narcisa
- Gonçalves Rita
- Gonçalves Rodrigo
- Gonçalves Rui
- Gonçalves Rui
- Gonçalves Óscar
- Gordo Clementina
- Gordo Sara
- Goulart Cássia L
- Goulão Beatriz
- Grande Carla
- Granjo Paulo
- Graveto João
- Graveto João
- Graveto João
- Graveto João
- Graça Anabela
- Graça Pedro
- Guedelha Daniel
- Guedes Jenifer
- Guedes Jenifer
- Guedes Joana
- Guerra Magda
- Guerreiro Sabrina L
- Guerrero Jose T
- Guerrero Jose T
- Guerrero José T
- Guerrero José T
- Guimarães Pedro
- Guimarães Teresa
- Guimarães Teresa
- Gusi Narcis
- Gutierrez Milagros L
- Hall Andreia
- Heitor Mª J
- Henriques Carolina
- Henriques Carolina G
- Henriques Mª A
- Hernandez-Martinez Francisco J
- Hernandez-Martinez Francisco J
- Hernández-Martínez Francisco-José
- Hesse Camilla
- Honório Samuel
- Honório Samuel
- Honório Samuel
- Honório Samuel
- Honório Samuel
- Horta Lina G
- Huertas Mª J T
- Iezzi Angelo
- Jardim Ana
- Jardim Helena G
- Jardim Jacinto
- Jesus C.
- Jesus C.
- Jesus Carlos
- Jesus Luís
- Jesus Rita
- Jesus Ângelo
- Jesus Ângelo
- Jesus Ângelo
- Jesus Ângelo
- Jimenez Nuria R
- Jimenez-Castuera Ruth
- Jimenez-Diaz Juan F
- Jimenez-Diaz Juan F
- Jimenez-Rodriguez Carla
- Jiménez-Díaz Juan-Fernando
- Jiménez-Díaz Juan-Fernando
- Jiménez-Rodríguez Carla
- Jordão Célia
- Jorge Arminda
- José Helena
- João Paulo V
- João Paulo V
- Jácome Cristina
- Jácome Cristina
- Kaliniczenco A.
- Kniess Rosiane
- Kranz Luís F
- Kranz Luís F
- Kraus Teresa
- Kraus Teresa
- Kretzer Marcia
- Kretzer Marcia
- Kretzer Marcia
- Kretzer Marcia
- Kretzer Marcia
- Kretzer Marcia
- Kretzer Marcia R
- Kretzer Márcia R
- Kurcgant Paulina
- Lacerda Josimari T
- Lacerda Josimari T
- Lacerda Josimari T
- Lage Isabel
- Lagoa Matilde
- Lains Jorge
- Lapa Leila
- Laranjeira Carlos
- Laranjo Mafalda
- Leal Jéssica
- Lebre Paula
- Lebre Sara
- Lee Huei D
- Leitão Catarina
- Leitão Céu
- Leitão Céu
- Leitão José A
- Lessa Paula A
- Leça Andrea
- Lima Adman S
- Lima Cristóvão F
- Lima Teresa M
- Lima Vera
- Lima-Basto Marta
- Lindo João
- Lindo João
- Lirk Gerald
- Lobato João
- Lobão Catarina
- Lopes Albino
- Lopes Carla
- Lopes Carla
- Lopes Elisa
- Lopes José C
- Lopes João
- Lopes Luci S
- Lopes Nuno
- Lopes Nuno V
- Lopes Nuno V
- Lopes Rui S
- Lopes Sara
- Lopes Saudade
- Loura Raquel
- Loureiro Isabel
- Loureiro Mª H
- Loureiro Mª H
- Loureiro Mª H
- Lourenço Georgina
- Lourenço Marina
- Louro Clarisse
- Louro Clarisse
- Louro Mª C
- Lousada Marisa
- Lousada Marisa
- Lousada Marisa
- Lumini José
- Luz Leonardo
- Luz Leonardo
- Luz Tatiana
- Luz Tatiana D
- Luís Henrique
- Luís Luís
- Luís Mª J
- Luís Sara
- Macedo Ana P
- Macedo António
- Macedo António
- Machado Idalina
- Machado Mª M
- Machado Patrícia O
- Machado Paulo
- Machado Paulo
- Machado Sara
- Madeira Teresa
- Madureira António
- Madureira António
- Magajewski Flávio
- Magalhães Carlos
- Magalhães Celina
- Magalhães Cátia
- Magalhães Cátia
- Magalhães Cátia
- Maia Ana S
- Maia Ana S
- Maia Ana S
- Maia Ana S
- Maia Bruno
- Maia Bruno
- Maia Carla
- Malheiro Isabel
- Malheiro Isabel
- Mangas Catarina
- Mangas Catarina
- Manso Conceição
- Manso M. C
- Marante Nídia
- Margarida Couto
- Marinho Daniel
- Marinho Sara
- Marques Alda
- Marques Alda
- Marques Alda
- Marques Alda
- Marques Alda
- Marques Alda
- Marques Alda
- Marques Alda
- Marques Alda
- Marques Ana R
- Marques António
- Marques Catarina
- Marques Cristiana
- Marques Cristiana
- Marques Daniel R
- Marques Daniel R
- Marques Fátima M
- Marques Mariana
- Marques Mariana
- Marques Mariana
- Marques Mariana
- Marques Mª F
- Marques Mário
- Marques Rita
- Marques Rita
- Marques Rita
- Marques Rita
- Marques Rita
- Marques Rita
- Marques Silvana F
- Marques Silvana F
- Marques Sílvia
- Marques Tatiana
- Marques-Rodrigues Alexandre
- Marques-Vieira Cristina
- Marquez Laura A
- Marsi Teresa O
- Marta-Simões Joana
- Marta-Simões Joana
- Marta-Simões Joana
- Marta-Simões Joana
- Martin Inmaculada Z
- Martinez-Hernandez Francisco
- Martinho Liliana
- Martins Ana R
- Martins Anabela C
- Martins Anabela C
- Martins Anabela C
- Martins Anabela C
- Martins Anabela C
- Martins Anabela C
- Martins Anabela C
- Martins Anabela C
- Martins Carlos R
- Martins Cristina
- Martins Cristina
- Martins Emília
- Martins Emília
- Martins Emília
- Martins Eveliny S
- Martins Fernando
- Martins Fátima
- Martins Julian
- Martins Laura
- Martins Maria M
- Martins Matilde
- Martins Matilde
- Martins Patrícia
- Martins Raul
- Martins Rosa
- Martín Ignácio
- Marôco João
- Marôco João
- Mata Mª A
- Mata Mª A
- Mata Mª A
- Mateus Artur
- Mateus Artur
- Matheus Filipe
- Matos Ana R
- Matos Filomena
- Matos Maria
- Matos Rui
- Medeiros Anabela
- Medeiros Dayse C
- Medeiros-Garcia Lurdes
- Medina María S
- Meireles Alexandra
- Melo Elsa
- Melo Elsa
- Melo Elsa
- Melo Flávio
- Melo Rosa
- Melo Rosa
- Melo Rosa
- Melo Rosa
- Mendes Aida
- Mendes Ana
- Mendes Ana
- Mendes Ana
- Mendes Ana L
- Mendes Ana L
- Mendes Ana L
- Mendes Elenice
- Mendes F
- Mendes F.
- Mendes Felismina
- Mendes Fernando
- Mendes Fernando
- Mendes Fernando
- Mendes Fernando
- Mendes Fernando
- Mendes Fernando
- Mendes Fernando
- Mendes Francisco
- Mendes Francisco
- Mendes Francisco
- Mendes Isabel
- Mendes Isabel
- Mendes Joana
- Mendes Maria F
- Mendes Pedro
- Mendes Pedro
- Mendes Pedro
- Mendes Pedro
- Mendes Pedro
- Mendes Pedro
- Mendes Pedro
- Mendes Romeu
- Mendes Romeu
- Mendes Romeu
- Mendes Zaida
- Mendonça Carlos
- Mendonça Nuno
- Mendonça Paula
- Mendonça Paula
- Mendonça Verónica
- Mendonça Verónica
- Meneghetti Vanize
- Meneses Rui
- Menezes Ruth L
- Menino Eva
- Menino Eva
- Menino Eva
- Menino Eva
- Mercê Cristiana
- Mesquita Helena
- Mesquita Helena
- Mesquita João R
- Midões Cristiana
- Milanés Gemma M
- Minas Bárbara
- Minghelli Beatriz
- Minghelli Beatriz
- Miranda Cristiana
- Miranda Marta
- Miranda Natacha F
- Monago Fatima M
- Monago Fatima M
- Monago Fátima M
- Monago Rocio M
- Monteiro Diogo
- Monteiro Helena
- Monteiro Joana
- Monteiro Lina
- Monteiro Luís
- Monteiro M. J
- Monteiro M. J
- Monteiro Mª J
- Monteiro Sílvia
- Morais Carminda
- Morais Marina A
- Morais Mª C
- Morais Mª C
- Morais Mª C
- Morais Mª C
- Morais Nuno
- Moreira Eliana
- Moreira Fernando
- Moreira Fernando
- Moreira Fernando
- Moreira Fernando
- Moreira Fernando
- Moreira Fernando
- Moreira Isabel
- Moreira Liliana
- Moreira Liliana
- Moreira Rita L
- Moreno Ana L
- Morgado Alice
- Morgado Sónia
- Morgado Sónia
- Morna Clementina
- Morna Clementina
- Morouço Pedro
- Morouço Pedro
- Mota Maria
- Mota Maria
- Mota Priscilla
- Moura Cynthia B
- Moura-Ramos Mariana
- Mouroço Pedro
- Mourão Ricardo
- Mártires Alice
- Mónico Lisete
- Mónico Lisete
- Mónico Lisete M
- Mónico Lisete M
- Mónico Lisete M
- Mónico Lisete M
- Mónico Lisete M
- Mónico Lisete M
- Nascimento Daniela
- Nascimento Maria S
- Nascimento V. B
- Natal Sônia
- Nave Filipe
- Nave Filipe
- Nazario Nazare
- Nazario Nazare
- Nazario Nazare
- Nazaré Cristina
- Nazário Nazaré O
- Neco Sofia
- Nelas Paula
- Neto João S
- Neves Carmo
- Neves Joana
- Neves Joel
- Neves Jéssica
- Neves Jéssica
- Neves Miguel
- Neves Sofia
- Neves Vanessa
- Nicola Paulo
- Nogueira Conceição
- Nogueira Paulo
- Nogueira Paulo
- Noné Ana
- Novais Sandra
- Novais Sandra
- Novais Sónia
- Novais Sónia
- Novo André
- Nugem Rita C
- Nugem Rita C
- Nunes Amélia
- Nunes Amélia F
- Nunes Carla
- Nunes Carla
- Nunes Carla
- Nunes Hélder
- Nunes Liliana
- Nunes S.
- Nuñez Cristina G
- Oliva Jefferson T
- Olivares Pedro R
- Oliveira Adriana
- Oliveira Ana
- Oliveira Ana
- Oliveira Ana
- Oliveira Ana I
- Oliveira Ana I
- Oliveira Ana I
- Oliveira Ana I
- Oliveira Ana I
- Oliveira Ana P
- Oliveira Anabela
- Oliveira Bibiana F
- Oliveira Bárbara
- Oliveira Camila A
- Oliveira Catarina
- Oliveira Denize C
- Oliveira Edmar S
- Oliveira Elizabete A
- Oliveira Emanuel
- Oliveira Eunice G
- Oliveira Eunice G
- Oliveira Isabel
- Oliveira Lara L
- Oliveira Manuel
- Oliveira Michelle T
- Oliveira Michelle T
- Oliveira Michelle T
- Oliveira Michelle T
- Oliveira Mirna F
- Oliveira Raul
- Oliveira Rita
- Oliveira Rita
- Oliveira Rita F
- Oliveira Rita F
- Oliveira Rita F
- Oliveira Sara
- Oliveira Sebastião T
- Oliveira Sebastião T
- Oliveira Suzete
- Oliveira Teresa C
- Oliveira Teresa T
- Oliveira Vânia P
- Olszewer Efrain O
- Ortiga Angela B
- Osório Nádia
- Osório Nádia
- Osório Nádia
- Osório Nádia
- Osório Nádia
- Pacheco José
- Padez Cristina
- Padilha José M
- Padilha José M
- Padilha José M
- Padilha José M
- Paixão S.
- Paixão Susana
- Paixão Susana
- Palmeira Lara
- Palmeira Lara
- Paraíso Nilson
- Paredes Hugo
- Parente Alexandra
- Parraça José A
- Parraça José A
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro D
- Parreira Pedro M
- Parreira Pedro M
- Parreira Pedro M
- Passadouro Rui
- Passadouro Rui
- Paulo Rui
- Paulo Rui
- Paulo Rui
- Paulo Rui
- Paulo Rui
- Paulo Rui
- Paúl Constança
- Paúl Constança
- Paúl Constança
- Pedreiro Ana
- Pedro Ana R
- Pedro Ana R
- Pedro Luísa
- Pedrosa Dora
- Pedroso Rosa
- Peixoto Ermelindo
- Peixoto-Plácido Catarina
- Peralta Teresa
- Pereira A.
- Pereira Alexandre
- Pereira Alexandre
- Pereira Ana
- Pereira Ana
- Pereira Ana
- Pereira Ana
- Pereira Ana M
- Pereira Ana M
- Pereira Ana M
- Pereira Ana T
- Pereira Ana T
- Pereira Anabela
- Pereira Carlos
- Pereira Carlos
- Pereira Carlos
- Pereira Carlos
- Pereira Carlos
- Pereira Cristina
- Pereira Elayne
- Pereira Elsa S
- Pereira Filipe
- Pereira Filomena
- Pereira Filomena
- Pereira Juliana
- Pereira Marta
- Pereira Olívia R
- Pereira Rafael
- Petrica João
- Petrica João
- Petrica João
- Petrica João
- Petrica João
- Pimenta Luís
- Pimenta Rui
- Pimentel Francisco
- Pimentel João
- Pimentel Rafaela
- Pinheiro Ana B
- Pinheiro Ana B
- Pinheiro Arminda A
- Pinheiro Patrícia C
- Pinho Cláudia
- Pinho Cláudia
- Pinho Cláudia
- Pinho Cláudia
- Pinho Cláudia
- Pinho Tânia
- Pinto Carlos
- Pinto Francisca
- Pinto Isabel C
- Pinto Isabel C
- Pinto J. L
- Pinto Joana
- Pinto M R
- Pinto Mª R
- Pinto Paulo F
- Pinto Sara
- Pinto Ítalo N
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pires Filipa
- Pires Filipa
- Pires Tânia
- Pires Tânia
- Pisco Jacinta
- Pivetta Hedioneia F
- Piñero Ana S
- Poeta Susana
- Porta-Nova Rui
- Postolache Gabriela
- Postolache Octavian
- Poço Mariana
- Prado Alessandro
- Prata Ana R
- Prebianchi Helena
- Presado Mª H
- Preto Vera
- Príncipe Fernanda
- Pulido-Fuentes Montserrat
- Pérez-Caballero Francisco L
- Pérez-Caballero Francisco L
- Queirós Paulo
- Quelhas Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Quintana-Montesdeoca Mª P
- Quirino Diogo
- Rabiais Isabel
- Rafael Helga
- Rainho Conceição
- Rainho Conceição
- Rainho Conceição
- Rama Luís
- Rama Luís
- Rama Luís
- Ramalhete Cátia
- Ramalho André
- Ramalho André
- Ramalho Fátima
- Ramalho Sónia
- Ramalho Sónia
- Ramalho Sónia A
- Ramirez Francisco B
- Ramirez Francisco B
- Ramos Maurício R
- Raposo Vítor R
- Rei Ana C
- Reina Mercedes G
- Reis Alcinda C
- Reis Ana S
- Reis Arsénio
- Reis Cláudia
- Reis Laura
- Reis Victor M
- Reses Manoela
- Reuter Éboni M
- Ribas Patrícia
- Ribeiro Andrea
- Ribeiro Andrea
- Ribeiro Diana
- Ribeiro Fernando
- Ribeiro Jaime
- Ribeiro Jaime
- Ribeiro José C
- Ribeiro João
- Ribeiro Lígia C
- Ribeiro Maria
- Ribeiro Maria
- Ribeiro Maximiano
- Ribeiro Olivério
- Ribeiro Olivério
- Ribeiro Samila G
- Ribeiro Sandra
- Ribeiro Sandra
- Ribeiro Óscar
- Ribeiro Óscar
- Ribeiro Óscar
- Ribeiro-Varandas Edna
- Richaud Sylvina
- Rocha C.
- Rocha Clara
- Rocha Clara
- Rocha Clara
- Rocha Mª C
- Rocha Mª C
- Rocha Saulo V
- Rocha Saulo V
- Rodrigo António
- Rodrigues Alexandre
- Rodrigues Alexandre
- Rodrigues Alexandrina
- Rodrigues António
- Rodrigues Cátia
- Rodrigues Diana
- Rodrigues Rogério
- Rodrigues Rogério
- Rodrigues Rogério
- Rodrigues Rosa
- Rodrigues Sandra
- Rodrigues Sandra
- Rodrigues Sandra
- Rodrigues Sandra
- Rodrigues Teresa
- Rodrigues Vítor
- Rodrigues Vítor
- Rodriguez Cláudia K
- Rodriguez-De-Vera Bienvendida C
- Rodriguez-De-Vera Bienvenida
- Rodriguez-De-Vera Bienvenida C
- Rodríguez Ana B
- Rodríguez-De-Vera Bienvenida-Del-Carmen
- Rombo João
- Roque Fátima
- Rosa Manuel S
- Rosa Marlene C
- Rosa Marlene C
- Rosa Marlene C
- Rosa Marlene C
- Rosa Marlene C
- Rosa Roger S
- Rosa Roger S
- Rosado António
- Rosado António
- Rosário Rafaela
- Ruben Rui B
- Ruivo Joana
- Saavedra Francisco
- Saboga-Nunes Luís
- Saboga-Nunes Luís
- Sala José A
- Sala José A
- Sales Tiago
- Salgueiro Anabela
- Salgueiro-Oliveira Anabela
- Salgueiro-Oliveira Anabela
- Salgueiro-Oliveira Anabela
- Salgueiro-Oliveira Anabela
- Salgueiro-Oliveira Anabela
- Salvador Mª C
- San-Martin Elisabete A
- Santana Miguel
- Santana Paula
- Santiago Conceição
- Santiago Eujcely C
- Santiago Eujcely C
- Santiago Luiz
- Santo Inês
- Santo Inês
- Santos Adriana
- Santos Ana
- Santos Bruno
- Santos Bruno
- Santos Erica
- Santos Flávia
- Santos Joana
- Santos Joana
- Santos Jorge
- Santos João
- Santos Leonino S
- Santos Luísa
- Santos Marina S
- Santos Marlene
- Santos Marlene
- Santos Nuno
- Santos Osvaldo
- Santos Osvaldo
- Santos Osvaldo
- Santos Rafael B
- Santos Rafael B
- Santos Sofia
- Santos Sofia
- Santos Sofia
- Santos Sofia
- Santos-Rocha Rita
- Sardo Dolores
- Sardo Pedro
- Sardo Pedro
- Sarmento-Ribeiro Ana B
- Sarreira-Santos Alexandra
- Sarroeira Cassilda
- Schneider Dulcineia
- Schneider Dulcineia
- Schneiders Paloma B
- Schroeder Silvana S
- Schukg Susann
- Seabra André
- Seabra Daniel
- Seabra Daniel
- Seabra Paulo
- Seixas Adérito
- Seixas Adérito
- Seixas Adérito
- Seixas Adérito
- Seiça Luís
- Seppänen Ulla-Maija
- Serapioni Mauro
- Serra Ana
- Serrano João
- Serrano João
- Serrano João
- Serrano João
- Serrano João
- Severino Sandy
- Siba Wafa A
- Silva Ana M
- Silva Ana M
- Silva Andrea G
- Silva André
- Silva Antónia
- Silva Armando
- Silva Carina
- Silva Carla R
- Silva Carlos
- Silva Carlos F
- Silva Catarina
- Silva Cláudia
- Silva Cláudia D
- Silva Daniel
- Silva Daniel
- Silva Darlen
- Silva David
- Silva Eduardo
- Silva Elsa
- Silva Ernestina
- Silva Helena R
- Silva Helena R
- Silva Iryna
- Silva Isabel
- Silva Joana
- Silva Joana
- Silva Joana
- Silva Luís D
- Silva Luís D
- Silva Maiza M
- Silva Manuel C
- Silva Margarida
- Silva Margarida
- Silva Maria A
- Silva Marilene
- Silva Marilene
- Silva Norberto
- Silva Paula
- Silva Paula A
- Silva Pedro
- Silva Pedro
- Silva Rafael
- Silva Rita
- Silva Rita
- Silva Rita P
- Silva Sara
- Silva Sara
- Silva Sara
- Silva Susana
- Silva Tatiane M
- Silva Vânia
- Silveira Paulo
- Sim-Sim Margarida
- Simões Alexandra
- Simões Cristina
- Simões João
- Simões Paulo C
- Simões Sónia
- Simões Ângela
- Siqueira Mariana S
- Siqueira Mariana S
- Soar Cláudia
- Soares Célia
- Soares Fátima
- Soares Fátima
- Soares Raquel
- Soares Salete
- Soares Sérgio
- Soares Valter
- Sousa Ana P
- Sousa Ana S
- Sousa Anderson R
- Sousa Anderson R
- Sousa Anderson R
- Sousa Anderson R
- Sousa Carla
- Sousa Caroline R
- Sousa Cesar
- Sousa D.
- Sousa Diana
- Sousa Gilberta
- Sousa Gilberta
- Sousa Gracinda
- Sousa Jani
- Sousa Joana
- Sousa Joana
- Sousa Luís
- Sousa Marina
- Sousa Marina
- Sousa Nelson
- Sousa Nelson
- Sousa Patrícia
- Sousa Patrícia
- Sousa Patrícia
- Sousa Patrícia
- Sousa Patrícia
- Sousa Patrícia
- Sousa Paulino
- Sousa Paulino
- Sousa Paulino
- Sousa Paulino
- Sousa Pedro
- Sousa Pedro
- Sousa Pedro
- Sousa Pedro
- Sousa Pedro
- Souza Clóvis A
- Souza Géssica M
- Souza Juliana A
- Souza Nelba R
- Souza Nelba R
- Spolaôr Newton
- Svensson Lola
- Sá Dayse
- Tapadas Rodrigo
- Tavares Aida I
- Tavares Ana
- Tavares Ana S
- Tavares José
- Tavares Mariline
- Tavares Nuno
- Teixeira A.
- Teixeira Ana
- Teixeira Ana
- Teixeira Ana M
- Teixeira Laetitia
- Teixo Ricardo
- Teles Patrícia
- Tena José M
- Tena Maria J
- Tenedório José A
- Tim-Tim Carolina
- Tomaz Jorge
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina C
- Tomás Teresa
- Topa Joana
- Torgal Jorge
- Torgal Jorge
- Torres Ana
- Torres Rui
- Trigo Africa P
- Trindade Inês A
- Trindade Inês A
- Trindade Inês A
- Trindade Inês A
- Tuna Ana R
- Tytgat Ite
- Uba-Chupel M.
- Uba-Chupel Mateus
- Ugalde Lierni U
- Ugartemendia Lierni
- Valado Ana
- Valado Ana
- Valado Ana
- Valado Ana
- Valado Ana
- Vale-Dias Luz
- Vale-Dias Maria L
- Valente Ana R
- Valente Carolina
- Valente Jorge
- Valente João
- Valim Frederico C
- Valim Frederico C
- Vaquinhas Marina
- Vaquinhas Marina
- Vaquinhas Marina
- Vaquinhas Marina
- Varandas Edna
- Vardasca Ricardo
- Vardasca Ricardo
- Vasconcelos Carlos
- Vasconcelos Carlos
- Vasconcelos Lélia R
- Vasconcelos Rita
- Vasconcelos Rita
- Vaz Daniela C
- Vaz Josiana A
- Vehreschild Viktor
- Vehreschild Viktor
- Veiga Nélio
- Veiga Nélio
- Veiga Nélio
- Veiga Nélio
- Veiga-Branco Mª
- Velosa Fábia
- Veloso Milene
- Ventura David
- Ventura Maria
- Ventura Rita
- Ventura Sandra
- Vicente Corália
- Vicente Corália
- Vicente Corália
- Vicente Sara
- Vicente Sónia
- Vidal Eglidia F
- Viega-Branco Maria
- Vieira André
- Vieira Margarida
- Vieira Viviane L
- Vieitez Juan G
- Villanueva Ana G
- Vincha Kellem R
- Vinha Ana F
- Virgolino Ana
- Vizzotto Betina P
- Vélez Marta M
- Welter Aline
- Xavier Ana
- Xavier Ana
- Xavier Sandra
- Xavier Sandra
- Zilhão Adriano
- Publication venue
- Publication date
- 01/01/2004
- Field of study
As part of an EU funded project to investigate the factors influencing bone preservation in the archaeological record, more than 250 bones from 41 archaeological sites in five countries spanning four climatic regions were studied for diagenetic alteration. Sites were selected to cover a range of environmental conditions and archaeological contexts. Microscopic and physical (mercury intrusion porosimetry) analyses of these bones revealed that the majority (68%) had suffered microbial attack. Furthermore, significant differences were found between animal and human bone in both the state of preservation and the type of microbial attack present. These differences in preservation might result from differences in early taphonomy of the bones. © 2003 Elsevier Science Ltd. All rights reserved
Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
- Abdullayev Seymur
- Abed Saeed
- Abelló David
- Abiola Olajide
- Abo mahadi Asmaa'
- Abo-khammash Areej
- Abou Chaar Mohamad K.
- Abou El.soud Moustafa Ramadan
- Abouelsoad Nervana
- Abraham Joyner
- Abreu da Silva Alberto
- Abu Ahammala Ayman B.
- Abu Al Amrain Mahmoud
- Abu Al-saleem Hasan
- Abu Alamrain Abdulwhhab
- Abu Alqumboz Amjad
- Abu Ataya Ahmed
- Abu hallalah Muad fathi khalleefah
- Abu Jamie Najlaa
- Abu Jayyab Israa
- Abu shua'ib Rana
- Abu Zainah Baraa
- Abu-Nimeh Samar
- Abu-Rous Mohammed R.
- Abu-srour Abrar
- Abuelhatal Hasan
- Abuelqomboz Ayham
- Abuhilal Baseel
- Abuhlaiga Ma'aly
- Abujamra Saleh
- Abukhalaf Sadi A.
- Abusalem Lana
- AbuSirrees Mahmoud
- Acevedo Veronica
- Acharya Rajgopal
- Achkasov Sergey
- Acosta Eric
- Adamo Karin
- Adamou Harissou
- Adams Jamie
- Adams Lawrence
- Adawi Samer
- Adebanjo Ademola
- Adel Marina
- Adel Sawsan
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji
- Adenuga Adedire
- Aderounmu Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesunkanmi Abdul-Rashid
- Adeyeye Ademola
- Adidharma Peter
- Adisa Adewale O
- Adnan Nour
- Afifi Amr Abdelghani
- Afifi Eman
- Afolayan Michael Olatunji
- Afzal Asma
- Agarwal Arnav
- Agarwal Raksheeth
- Agbakwuru Augustine
- Agbeko Anita Eseenam
- Aguilar Martinez Maria Del Mar
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlqvist Sandra
- Ahmad Izzuddin Ahmad Imran
- Ahmad Kasim
- Ahmad Sarwat
- Ahmed Ahmedgaber
- Ahmed Hazem Abdelkarem
- Ahmed Mariam
- Ahmed Nabila
- Ahmed Zahra
- Ainoa Eppu
- Aithie Joanna M S
- Ajani Costanza
- Ajao Akinlabi
- Ajiboye Anthony
- Ajmera Ankit
- Akande Oluwatosin
- Akaydin Elif
- Akbaba Ata Cem
- Akbar Sana Amir
- Akeel Nouf
- Akeem Aderogba Adeleke
- Akin Alp
- Akinkuolie Akinbolaji
- Akisheva Aygulya
- Akitikori Mabel Temisanren
- Akrida Ioanna
- Aktas Melik Kagan
- Al basos Iyad
- Al Farsi Maryam
- Al Nassrallah Majdi
- Al Sagheir Eman
- Al Saqqa Sara
- Al Saqqa Sara
- Al-Allaf Omar
- Al-Busaidi Ibrahim S.
- Al-Dhufri Ali
- Al-Himyari Hamza S.
- Al-Masri Mahmoud
- Al-Najjar Hani
- Al-Sabbagh Yusra
- Al-Shwaikh Samar
- Al-Slaibi Ibrahim
- Al-Taher Raed
- Al-Tammam Hiba
- Alabuzidi Aya
- Alagha Othman
- Alammarin Mohammad
- Alapatt John
- Alasttal Mohammed
- Alatise Olusegun Isaac
- Albaggar Marwa
- Albahnasawi Moath A.
- Albati Naif
- Alberga Anna
- Alberts Justin
- AlBsoul Ahmad
- Albsoul Nader
- Alcorta Rodrigo
- Alejandre Villalobos Cristina
- Alemdag Gökçe nur
- Alexander Philip
- Alfarra Nada
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- Dominguez Joaquina
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- Eusebio Zegarra Ivan Edward
- Ezzat Helmy
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- Fahmawee Toqa
- Fairfield Cameron J
- Falato Armando
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- Figueiredo Ana Gabriela
- Finlay Ben
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- Impellizzeri Harmony
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- Infante Pino Hugo
- Ingabire J.C. Allen
- Innocent Aryon
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- Ye Geoffrey
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- Zaffaroni Gloria
- Zahra Baryab
- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
- Zambrana Campos Vanesa
- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ângelo Miguel
- Älgå Andreas
- Çolak Elif
- Ümarik Toomas
- Šatkauskas Mindaugas
- Škimelyte Monika
- Šlenfuktas Vygintas
- Šuman Oliver
- Žatecký Jan
- Žumbakys Žygimantas
- Župan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 30/01/2021
- Field of study
© 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
- Abdullayev Seymur
- Abed Saeed
- Abelló David
- Abiola Olajide
- Abo mahadi Asmaa'
- Abo-khammash Areej
- Abou Chaar Mohamad K.
- Abou El.soud Moustafa Ramadan
- Abouelsoad Nervana
- Abraham Joyner
- Abreu da Silva Alberto
- Abu Ahammala Ayman B.
- Abu Al Amrain Mahmoud
- Abu Al-saleem Hasan
- Abu Alamrain Abdulwhhab
- Abu Alqumboz Amjad
- Abu Ataya Ahmed
- Abu hallalah Muad fathi khalleefah
- Abu Jamie Najlaa
- Abu Jayyab Israa
- Abu shua'ib Rana
- Abu Zainah Baraa
- Abu-Nimeh Samar
- Abu-Rous Mohammed R.
- Abu-srour Abrar
- Abuelhatal Hasan
- Abuelqomboz Ayham
- Abuhilal Baseel
- Abuhlaiga Ma'aly
- Abujamra Saleh
- Abukhalaf Sadi A.
- Abusalem Lana
- AbuSirrees Mahmoud
- Acevedo Veronica
- Acharya Rajgopal
- Achkasov Sergey
- Acosta Eric
- Adamo Karin
- Adamou Harissou
- Adams Jamie
- Adams Lawrence
- Adawi Samer
- Adebanjo Ademola
- Adel Marina
- Adel Sawsan
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O
- Adenuga Adedire
- Aderounmu Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesunkanmi Abdul-Rashid
- Adeyeye Ademola
- Adidharma Peter
- Adisa Adewale
- Adisa Adewale O
- Adnan Nour
- Afifi Amr Abdelghani
- Afifi Eman
- Afolayan Michael Olatunji
- Afzal Asma
- Agarwal Arnav
- Agarwal Raksheeth
- Agbakwuru Augustine
- Agbeko Anita Eseenam
- Aguilar Martinez Maria Del Mar
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlqvist Sandra
- Ahmad Izzuddin Ahmad Imran
- Ahmad Kasim
- Ahmad Sarwat
- Ahmed Ahmedgaber
- Ahmed Hazem Abdelkarem
- Ahmed Mariam
- Ahmed Nabila
- Ahmed Zahra
- Ainoa Eppu
- Aithie Joanna M S
- Ajani Costanza
- Ajao Akinlabi
- Ajiboye Anthony
- Ajmera Ankit
- Akande Oluwatosin
- Akaydin Elif
- Akbaba Ata Cem
- Akbar Sana Amir
- Akeel Nouf
- Akeem Aderogba Adeleke
- Akin Alp
- Akinkuolie Akinbolaji
- Akisheva Aygulya
- Akitikori Mabel Temisanren
- Akrida Ioanna
- Aktas Melik Kagan
- Al basos Iyad
- Al Farsi Maryam
- Al Nassrallah Majdi
- Al Sagheir Eman
- Al Saqqa Sara
- Al Saqqa Sara
- Al-Allaf Omar
- Al-Busaidi Ibrahim S.
- Al-Dhufri Ali
- Al-Himyari Hamza S.
- Al-Masri Mahmoud
- Al-Najjar Hani
- Al-Sabbagh Yusra
- Al-Shwaikh Samar
- Al-Slaibi Ibrahim
- Al-Taher Raed
- Al-Tammam Hiba
- Alabuzidi Aya
- Alagha Othman
- Alammarin Mohammad
- Alapatt John
- Alasttal Mohammed
- Alatise Olusegun Isaac
- Albaggar Marwa
- Albahnasawi Moath A.
- Albati Naif
- Alberga Anna
- Alberts Justin
- AlBsoul Ahmad
- Albsoul Nader
- Alcorta Rodrigo
- Alejandre Villalobos Cristina
- Alemdağ Gökçe nur
- Alexander Philip
- Alfarra Nada
- Alfitory Asma
- Alhabil Belal
- Alhaj Ahmad
- Alherz Mohammad
- Alhimyar Maryam
- Ali Ahmad Syed Mustafa
- Ali SANI Samuel
- Ali Amr
- Ali Asmaa
- Ali Mahmoud
- Ali Shabina
- Alimi Marjan
- Aliosin Oleg
- Aliyu Halima
- Aljaafreh Almoutuz
- Aljaber Dana
- Aljaberi Loay
- Aljanfi Asma
- Aljiffry Murad
- Aljohmani Lylas
- Alkhaledi Ahmad
- Alkhatib Ala'a Aldeen
- Alkhatib Haya
- Alkhatib Mo'min
- Allen Ingabire J.C.
- Almasri Murad
- Almeida Braga Sara
- Almeida Filipe
- Almigheerbi Alabas
- Almoqayyad Abdelrahman
- Almuzghi Fakhruddin
- Alnoury Mostafa
- Alonso Batanero Ester
- Alqadi Mohammad
- Alsaid Bayan
- Alsalameh Barah
- Alsallaq Osama
- Alser Osaid
- Alshaar Muhammad
- Alsharef Tagwa
- Alsharqawi Nourah
- Alswerki Mohammad
- Altaf Amna
- Altaf Rabiya
- AlTaweel Mohammed
- Althini Abdulmunem Ahmed Mustafa
- Altibi Ahmed M.
- Altinel Yuksel
- Altiner Saygin
- Altomare Donato Francesco
- Altumei Zohoor
- Alvarez Rivera Alvaro Eduardo
- Alvarez-Cano Alethia
- Alves do Canto Brum Homero
- Alves Daniela Macedo
- Alves Magda
- Alvi Abdul
- Alwaheidi Malak
- Alwali Abdallah
- Alwerfally AbdulMawlay
- Alwhaidi Noor
- Alyafi Amr
- Alzabti Fatima
- Alzahaf Ahmed
- AlZohour Mohammad
- Amadou Magagi Ibrahim
- Amandito Radhian
- Amarin Justin Z.
- Amaro Margarida
- Ambrazevicius Marijus
- Amendola Alfonso
- Amin Leila
- Amine Souadka
- Amjad Talal
- Amorim Edgar
- Amro Adham
- Anandan Premkumar
- Anas khalifa Rawda
- Anastasio Lorenzo
- Andersson Yvette
- Andreotti Dario
- Andrew David
- André Benoît
- Ang Sue Ean
- Angel Miguel
- Anggita Gultom Phebe
- Annapureddy Naga
- Anokhin Evgeny
- Ansaloni Luca
- Ansarei Dhirar
- Ansari Abdul Basit
- Antaky Marco
- Anthony Natasha
- Anthoulakis Christos
- Antonopoulou Maria Ioanna
- Anwar Mohamed
- Anwer Abdul Wahid
- Anyanwu Chikamuche
- Anyanwu Lofty-John
- Anyanwu Mercy Chinemerem
- Anyomih Theophilus Teddy Kojo
- Appukuttan Akhila
- Aquilino Fabrizio
- Archibald Jess
- Arciénega Yañez María del pilar
- Argentou Maria-Ioanna
- Argudo Nuria
- Argyriou Eleftherios Orestis
- Arias Madrid Natalia
- Aribi Sarra
- Arifin Ghafur Rasyid
- Arizpe Daniel
- Arnaud Alexis P
- Arora Bharti
- Arora Deeksha
- Arowolo Olukayode
- Arrangoiz Rodrigo
- Arslan Ekin
- Artigau Eva
- Ashfaq Ahsan
- Ashour Dina
- Ashour Firas
- Ashoushan Hana
- Ashraf Ahmed
- Ashraf Alaa
- Asif Ashar
- Asnel Dorisme
- Asok Anjitha
- Assa Rawan
- Assalhi Mohamed
- Asta Martina
- Asti Emanuele Luigi Giuseppe
- Atakul Onur
- Atallah Khalid
- Atanasov Boyko
- Atawneh Mohammad
- Athamneh Sarah
- Ather Muaaz
- Athisayaraj Thomas
- Atkociunas Aivaras
- Attia Mohamed
- Au Angela
- Awad Israa
- Awadallah Haneen
- Awaji Kholoud
- Awesat Eman
- Awolowo Ajibola
- Ayandipo Omobolaji
- Ayash Mohammad
- Ayau Fernanda
- Ayesh Kholoud
- Ayman El-sawy Esraa
- Ayoub Rami
- Aytac Erman
- Ayub Bushra
- Ayub Saima
- Ayyad Rawan
- Azevedo José
- Azodo Ijeoma
- Azzubia Joma
- B L Ashika
- Ba Mouhamadou Bachir
- Babaa Basheer
- Babirye Lilian
- Bacic Ivan
- Badr Esraa Tarek
- Badr Helmy
- Badran Abdul
- Badwe Rajendra
- Bafford Andrea Chao M.D.
- Baggaley Caitlin
- Bahroun Sumayyah Ghayth
- Baiao José Miguel
- Baiocchi Daniella
- Bairos Menezes Maria
- Baiu Ioana
- Bajilan Mohammad
- Bajomo Oreoluwa
- Bake Jacques
- Baki Bahadir Emre
- Bakoleas Panagiotis
- Balaawi Reem
- Balalis Dimitrios
- Balata Mohamed
- Balkarov Artem
- Ballouhey Quentin
- Balogun Olanrewaju
- Baloyiannis Ioannis
- Baltaci Ege
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- Basso Stefano Maria Massimiliano.
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- Dominguez Joaquina
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- Falato Armando
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- Forero-Torres Alexander
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- Ghellai Ali M.
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- Gnintedeme Olivier Tchianze
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- Sultan Ahmed
- Summerour Virginia
- Sund Malin
- Sundar Sudha
- Sung Chia-Yen
- Suradi Haya H.
- Suresh Gayathri
- Suresh Rishi
- Sushkov Oleg
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- Syed Bilal
- Syllaios Athanasios
- Sylvester Kimutai
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- Szyszka Bartosz
- Sánchez Suárez Ramses
- Sánchez-García Jorge
- Sánchez-Guillén Luis
- Søreide Kjetil
- Tababa Osama
- Tabiri Stephen
- Tagliabue Fulvio
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- Taha Ehab
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- Tai Aswan
- Taiwo Agboola
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- Winiarski Marek
- Winoto Hadi
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- Winter Des
- Wisal Maham
- Wisselink Daan
- Wogensen Fredrik
- Wondoh Paul M.
- Wong Florence
- Wong Hsu Ven
- Wong Jane J
- Wong Jeremy
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- Wong Sui-Weng
- Wong Tsz Lun Ernest
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- Woon-Shoo-Tong Xiao-Ming Sarah
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- Xanthopoulou Georgia
- Yabut Kenneth
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- Yaghi Nadine
- Yaghi Yasmine
- Yahia Mohamed Ali Mohamed
- Yakushkina Al'ona
- Yalçinkaya Ali
- Yang P Zichu
- Yanikoğlu Erkan
- Yanni Fady
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- Ye Geoffrey
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- Yenli Edwin
- Yeo Jeremy
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- Yeşilsancak Merve
- Yildirim Reyyan
- Yildiz Alp
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- Yong Shun Qi
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- Yusuf Baasil
- Yüksel Osman
- Zabiyaka Mikhail
- Zachariah Sanoop Koshy
- Zafar Syed Nabeel
- Zaffaroni Gloria
- Zahra Baryab
- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
- Zambrana Campos Vanesa
- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ângelo Miguel
- Älgå Andreas
- Çolak Elif
- Ümarik Toomas
- Čepuliené Daiva
- Şahin Can
- Šatkauskas Mindaugas
- Škimelytè Monika
- Šlenfuktas Vygintas
- Šuman Oliver
- Žatecký Jan
- Žumbakys Žygimantas
- Župan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/07/2022
- Field of study
© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23–0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research
The surgical safety checklist and patient outcomes after surgery: a prospective observational cohort study, systematic review and meta-analysis
- Author
- Ab Majid Mohd Azuan
- Ab Rahman Ahmad Sufian
- Ab Rahman Rusnah
- Abayasinghe Chamika
- Abbas Muntadhar
- Abbott T. E. F.
- Abbott Tom
- Abd Ghafar Fara Nur Idayu
- Abd Hadi Husni Zaeem
- Abdel Goad Ehab Helmy
- Abdullah Noor Hairiza
- Abdur-Rahman Lukman
- Abeloos Jacques
- Abernethy Caroline
- Abidin Ucu Nurhadiat
- Abrunhosa Alexandra
- Absar Mohammed
- Adam Suwayba
- Adams David
- Adams George
- Adamson Michael
- Adekola Oyebola
- Adelaja Yemi
- Ademola Adeyinka
- Adenekan Anthony
- Adenike Odewabi
- Adeolu Augustine A.
- Adetoye Adedapo
- Adewale Badru
- Adigun Tinuola
- Adolfsson Anne
- Africander Cucu
- Afshari Arash
- Agarwal Vandana
- Agodirin Olayide
- Aguzzoli Crisitiano
- Ahamed khader null
- Ahmad Azam Ummi Azmira
- Ahmad Abdurrahman
- Ahmad Norfaizan
- Ahmad T.
- Ahmad Tahania
- Ahmad Yousra
- Ahmed Ahmed
- Ahmed Jamil
- Ahmed Tahania
- Ai Yanqiu
- Aignatoaie Mariana
- Aimoniotou-Georgiou Eleni
- Akanmu Olanrewaju
- Akerman Nik
- Akinwale Mukaila
- Al Anizi Mashel
- Al hussaini Sabah
- Al'Amri Khalid
- Al-Soudaine Yassr
- Aladin Hafiz
- Alagbe-Briggs Olubusola
- Albaj Safauldeensalem
- Alberto Lisi Zaheer Moolla
- AlbertoVolta Carlo
- Alcock David
- Alcock Liam
- Aldecoa Cesar
- Aleixo Fábia Berganton
- Alexander Hazel
- Alexander Maini
- Alexander-Sefre Farhad
- Alherz Fadhel
- Ali Hani
- Ali Marlynn
- Ali Sarah
- Alias Abdul Hafiz
- Alias Anita
- Alit Mahaalit Aribawa
- Allen Samantha
- Allen Sara Jane
- Allison Joanna
- Alloj Chiara
- Allorto Nikki Leigh
- Allsop Joanne
- Almeida William
- Alonso Eduardo
- Alonso José Ignacio
- Alphonsus Christella
- Alvares Danielle
- Alves Maria Joao
- Amador Juan Carlos Bravo
- Ameer Yusuf
- Amendola Cristina Prata
- Ami Noam
- Amstrup-Hansen Louise
- Anagnou Athina
- Andersen Cheme
- Anderson Charlotte
- Anderson Colette
- Anderson Frank
- Anderson Philip
- Andreadaki Evangelia
- Andreou Alexandros
- Andreou Prematie
- Andrew Alyson
- Andrews Emma
- Angermair Stefan
- Angus Kirsty
- Anillo Victor
- Antal Oana
- Antill Philip
- Antoniadou Eleni
- Antonina Webombesa
- Apagaki Eymorfia
- Apostolou Konstantinos
- Applewhaite Christopher
- Aquino Laura Patricia González
- Ar Praburaj
- Arawwawala Dilshan
- Ardern Diane
- Argue Ruth
- Arkalaki Eleni
- Arlo whitehouse null
- Armaganidis Apostolos
- Armstrong John
- Armstrong Richard
- Arnaoutoglou Christina
- Arnaoutoglou Elena
- Arnold Glenn
- Arrandale Lindsay
- Arrich James
- Arrigo Mario
- Arshad Homa
- Arshad Mohammed Asif
- Artiles Tania Socorro
- Arumugam Swarna
- Arustei Mirela
- Arvaniti Kostoula
- Arya Aryabiantara
- Arya Shobhit
- Asimakos Andreas
- Aslam F Noorbhai M.
- Asudo Felicia
- Athanasakis Elias
- Atiku Mamuda
- Attrill Elizabeth
- Attwood Clare
- Auer Patrick
- Avidan Michael
- Avila Erendira Jocelin Dominguez
- Avis Joanne
- Awad Hadi
- Axioti Elena
- Azambuja Pedro
- Azevedo Caroline
- Aziz Faizal Zuhri
- Baas Peter
- Baghirzada Leyla
- Bai Hui-Ping
- Bai Yun
- Baillie Shelley
- Baines Duncan
- Baio Thalissa Hermínia
- Bairaktari Aggeliki
- Baker Gerard
- Baker Katie-Anne
- Baker Paul
- Balain Birender
- Balaji Packianathaswamy
- Balajonda Naraida
- Balanescu Andreea
- Balasubramaniam Madhu
- Baldisserotto Sérgio
- Baldwin Jacqueline
- Baldwin Matthew
- Balfoussia Danai
- Bali Christina
- Bandeira Maria Expedito
- Banerjee Robin
- Bankewitz Carla
- Banner-Goodspeed Valerie
- Bao Qi
- Barcraft-Barnes Helena
- Barneto Lisa
- Barnett Andrew
- Baroselli Antonio
- Barraclough James
- Barras Jean-Pierre
- Barrett Stephen
- Barrett Wendy Joan
- Basanth Sujith
- Batchelor Nick
- Bateman Brian
- Bates Alexander
- Bates Sarah
- Batista Hugo Dias
- Bauchmuller Kris
- Bauer Marlene
- Baumgarten Georg
- Baxter Linden
- Beaton Ceri
- Beattie Scott
- Beavis Vanessa
- Beavis Vanessa
- Bechan Sudha
- Bejia Tarek
- Belciu Ioana
- Belda Margarita Tormo
- Bell Gillian
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- Bell Stephanie
- Bellandi Mattia
- Bello Jibril
- Beloeil Helene
- Belskiy Vladislav
- Beltran Anna Valle
- Ben-Menachem Erez
- Benavent Pau
- Benedikt Preckel Osne Kirzner
- Benevento Angelo
- Bengeri Sheshagiri
- Bennett Cambell
- Bennett Michael
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- Berntsen Emer
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- Bester Delia
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- Bettega Fernanda
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- Bhardwaj Neeraj
- Bhatia Kailash
- Bhula Chettan
- Bi Yanbing
- Biais Matthieu
- Biccard B. M.
- Biccard Bruce
- Biccard Bruce M.
- Bidd Heena
- Bidgoli Jawad
- Biffen Andrew
- Bignami Elena
- Bilolikar Anjali
- Bin Mustapha Mohd Tarmimi
- Birch Julie
- Bishop David Gray
- Biyase Thuli
- Bizios Christol
- Blackwell Clare
- Blackwood Douglas
- Blaj Mihaela
- Blakemore Stephen P.
- Bland Martin
- Blunt Mark
- Blyth Katharine
- Bocchino Speranza
- Bodansky Daniella
- Bodger Phoebe
- Boer Christa
- Boereboom Catherine
- Boggiano Victoria
- Bogner Gerhard
- Bokkel-Andela Janneke ten
- Bolaji Benjamin
- Bolton David
- Boone Myles
- Boschi Luca
- Boshier Piers
- Botes Marisa
- Botis Ioannis
- Bottini Corrado
- Bottrill Fiona
- Bouchez Stefaan
- Boulton Kerenza
- Bouris Vasilios
- Bourner Lynsey
- Boutsikos Georgios
- Bouwman Arthur
- Bowrey Sarah
- Boxall Leigh
- Boyd Christine
- Bradburn Mike
- Bradley Jacqueline
- Branagan Graham
- Branco Teresa
- Brand Bastiaan
- Brandsborg Birgitte
- Breitenstein Stefan
- Brennan Andrew
- Brennan Emma
- Brenner Laura
- Brincat Maximilian
- Briscoe Richard
- Bristogiannis Sotirios
- Brooke Jenny
- Brookes Jamie
- Brookes Morag
- Brooks Carolyn
- Broomby Rupert
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- Brown Andrew
- Brown Caroline Wrey
- Brown Gemma
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- Brown Lynne
- Brown Richard
- Brown Robyn
- Browning Julie
- Bruma Dana
- Brunete Tamara
- Brunswicker Annemarie
- Bryant Helen
- Bua Emmanuel
- Buccimazza Ines
- Buckley Sarah
- Buerkle Christian
- Buhre Wolfgang
- Builu Pierre Monji
- Buise Marc
- Bullock Clare
- Bunwarie Bimalshakth
- Burns Karen
- Burrows Lorna
- Burrows Tom
- Burston Ben
- Burtenshaw Andrew
- Burton Megan
- Busuioc Mihai
- Butryn Izabella
- Butt Georgina
- Byrne Kelly
- Bührer Thomas
- Cabezuelo Estefania
- Cabral Raquel
- Cabral Tiago do Nascimento
- Cabrini Luca
- Cacala Sharon
- Cai Fang
- Cai Yunfei
- Cain Helen
- Cairns Carel
- Cakova Veronika
- Calderwood Claire
- Callaghan Mark
- Campbell Debbie
- Campbell Doug
- Campbell Douglas
- Campbell Gill
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- Campbell Kathleen
- Campbell Marta
- Campbell Tara
- Campey Lorraine
- Camsooksai Julie
- Cancho David
- Candido Keulle
- Cang Jing
- Cannavo' Maurizio
- Cao Jianqiao
- Cao Ying
- Cao Zhongming
- Cardellino Silvano
- Cardosa Jorge
- Cardoso Gutemberg
- Cardy Jon
- CarmenVaida Laura Aflori
- Carmino Livio
- Carp Cristina Paula
- Carr Adrienne
- Carrera Ronald
- Carroll Christine
- Carroll Jo
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- Castaño Beatriz
- Castle Gail
- Cavanagh Sarah
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- Cernea Daniela Denisa
- Chaddock Mark
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- Chan Matthew
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- Chan Weng Ken
- Chan Yik Lam
- Chande Shiv
- Chandler Ben
- Chandra Susilo
- Chandrasekharan Shardha
- Chang Yuan Hsuan
- Chaniotaki Fotini
- Charitos Efthimios
- Charlalampidoy Alexandra
- Charles Rob
- Chatterjee Devnandan
- Chatterjee Jayanta
- Chatzimichali Chatzimichali Aikaterini
- Chau Simon
- Chazova Elena
- Cheah Clarissa
- Cheah Seleen
- Cheeseman Michelle
- Cheing Yushio
- Chen Chao
- Chen Chen
- Chen Feifei
- Chen Fumei
- Chen Hong
- Chen James
- Chen Junping
- Chen Lee-lynn
- Chen Linbi
- Chen Liyong
- Chen Pushan
- Chen Qiang
- Chen Rong
- Chen Shasha
- Chen Shiyu
- Chen Sijia
- Chen Yaqiu
- Chen Yijiao
- Chen Yijun
- Chen Yongjie
- Chen Zhang
- Cheng Baoli
- Cheng Ka Ho
- Cheng Zhonggui
- Cheong Edward
- Cherian Ritchie
- Cherrett Veronica
- Chetty Rubendraj R.
- Chew M. S.
- Chew Michelle
- Chhabra Ashok
- Chicken Dennis-Wayne
- Chilinciuc Ion
- Chin Im Im
- Chirkut Subash
- Chlorou Dimitra
- Choi Hyun-min David
- Choi Stephen
- Chow Lorraine
- Christian Rachel
- Christiansen Ida Cecilie
- Christmas Natasha
- Christodoulidis Gregory
- Christodoulopoulou Theodora
- Christofaki Maria
- Christoforidis Dimitri
- Chronis Christos
- Chu Hiu Man
- Chu Susanna
- Chua Pandora
- Chukkambotla Srikanth
- Chung Chun Kwong Eric
- Cifra Elna
- Ciobanu Cristina
- Ciobotaru Oana Roxana
- Cirstea Emanuel
- Clark Richard
- Clarkson Aisling
- Clarkson Rachel
- Clavien Pierre-Alain
- Claxton Andrew
- Clemmons Karen
- Cloro Luigi Maria
- Clyde Antony
- Cobzaru Isabelle
- Codita Anisoara
- Colangelo Antonio
- Colangelo Chiara
- Colling Kerry
- Collins Hannah
- Collins Michelle
- Collins Nwokoro
- Colvin Carolyn
- Commey Thelma
- Comptaer Nicolas
- Conde Carlos
- Conradie Alae
- Constantin Kathryn
- Cook Tim
- Cooper Lauren
- Cooper Lucy
- Cooper Mariese
- Cooper Richard
- Cooper Sarah
- Copaciu Elena
- Cope Jennifer
- Copetti Elisa
- Copley Edward
- Copotoiu Sanda Maria
- Coppens Marc
- Corneci Dan
- Cornell Jonathan
- Cornish Julie
- Correia da Silva Rui Freitas Mendonça
- Corti Daniele
- Costa Ana Cristina Miranda Martins
- Costanzo Eleonora
- Costelloe Hannah
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- Cripps Heather
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- D'Andrea Rocco
- Dafnios Nikolaos
- Dai Hanying
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- Dai Qinxue
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- De Andrés Ibanez José Antonio
- De Baerdemaeker Luc
- de Beer Johan
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- Delgado García David R.
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- Zangrillo Alberto
- Zapata Darcy Danitza Mari
- Zbitnew Geoff
- Zeidan Lisa
- Zeng Qiuting
- Zerman Luiza
- Zettergren Jan
- Zhang Baoling
- Zhang Enman
- Zhang Hongyan
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- Zhang Shihai
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- Zhang Xiaoyan
- Zhang Xuekang
- Zhang Yan
- Zhang Yapping
- Zhang Ye
- Zhang Yuan
- Zhao Bing
- Zhao Bo
- Zhao Chong
- Zhao Jiashi
- Zhao Jinning
- Zhao Lei
- Zhao Lili
- Zhao Shuna
- Zhao Ting
- Zhao Weihong
- Zhao Weilu
- Zhao Xiaoying
- Zhen Jungang
- Zheng Kang
- Zheng Lina
- Zheng Tianzhao
- Zhong Yi
- Zhou Ce
- Zhou Dachun
- Zhou Haidong
- Zhou Haiyan
- Zhou Jiali
- Zhou Jialong
- Zhou Jing
- Zhou Xian-jin
- Zhu Xiaomao
- Zhu Xiaoping
- Zhu Yi
- Zhu Zhipeng
- Zhuang Xiuxiu
- Zilis Georgios
- Zingerle Nicolette
- Zingg Urs
- Zoerner Frank
- Zonneveldt Harry
- Zou Xiaohua
- Zoulamoglou Menelaos
- Zsisku Lajos
- Åkring Irene
- Ögren Katrin
- Publication venue
- Health Sciences Research Commons
- Publication date
- 30/10/2017
- Field of study
© 2017 British Journal of Anaesthesia Background: The surgical safety checklist is widely used to improve the quality of perioperative care. However, clinicians continue to debate the clinical effectiveness of this tool. Methods: Prospective analysis of data from the International Surgical Outcomes Study (ISOS), an international observational study of elective in-patient surgery, accompanied by a systematic review and meta-analysis of published literature. The exposure was surgical safety checklist use. The primary outcome was in-hospital mortality and the secondary outcome was postoperative complications. In the ISOS cohort, a multivariable multi-level generalized linear model was used to test associations. To further contextualise these findings, we included the results from the ISOS cohort in a meta-analysis. Results are reported as odds ratios (OR) with 95% confidence intervals. Results: We included 44 814 patients from 497 hospitals in 27 countries in the ISOS analysis. There were 40 245 (89.8%) patients exposed to the checklist, whilst 7508 (16.8%) sustained ≥1 postoperative complications and 207 (0.5%) died before hospital discharge. Checklist exposure was associated with reduced mortality [odds ratio (OR) 0.49 (0.32–0.77); P\u3c0.01], but no difference in complication rates [OR 1.02 (0.88–1.19); P=0.75]. In a systematic review, we screened 3732 records and identified 11 eligible studies of 453 292 patients including the ISOS cohort. Checklist exposure was associated with both reduced postoperative mortality [OR 0.75 (0.62–0.92); P\u3c0.01; I2=87%] and reduced complication rates [OR 0.73 (0.61–0.88); P\u3c0.01; I2=89%). Conclusions: Patients exposed to a surgical safety checklist experience better postoperative outcomes, but this could simply reflect wider quality of care in hospitals where checklist use is routine
Critical care admission following elective surgery was not associated with survival benefit: prospective analysis of data from 27 countries
- Author
- A T Landers
- Aaron Lawson McLean
- Abbey Paton
- Abdel Razzaq Khalaf
- Abdul Hafiz Alias
- Abdurrahman Ahmad
- Abegail Salvana
- Abigail Keen
- Abigail Patrick
- Abraham Hulst
- Acela G Lopez
- Adam Evans
- Adam Rehak
- Adamu Muhammad Sarki
- Ade Nurkacan Dursin
- Ade Susanti
- Adela Ruiz
- Adeline Rankin
- Ademola Talabi
- Adenekan Adetoye
- Adeoluwa Tayo
- Adeyinka Ademola
- Aditi Kulkarni
- Aditi Naik
- Aditi Shrivastava
- Adriana Krepil
- Adrianna Woolsey
- Adrianna Woolsey
- Adrienne Carr
- Afolabi Owojuyigbe
- Aggeliki Bairaktari
- Agoritsa Tsioka
- Agostino Roasio
- Ahamed Khader
- Ahmad Sufian Ab Rahman
- Ahmed Ahmed
- Ahmed El-Sayed
- Ahmed Saloojee
- Ahmed Sayeed
- Aida Tantri
- Aida Tantri
- Aikaterini Chatzimichali
- Aikaterini Kyparissi
- Aikaterini Makatounaki
- Aisling Clarkson
- Ajay Gupta
- Akanmu Durodola
- Akbar Vohra
- Akbar Vohra
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- Shiva Tripathi
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- Shiyu Chen
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- Suparna Das
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- Susanne Sonnemann
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- Susilo Chandra
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- Tinuolac Adigun
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- Ulf Kessler
- Ulrich Goebel
- Ulrika Winstone
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- Urs Zingg
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- Vaia Aliki Rompou
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- Vanessa Beavis
- Vanessa Beavis
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- Vasilios Bouris
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- Veerle Van Mossevelde
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- Veronica Cherrett
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- Victoria Freeman
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- Victoria Martinson
- Victoria Phelps
- Vieri Parrini
- Vikas Kaura
- Vilavan Koompirochana
- Vimal Hariharan
- Vincent Chan
- Vineshykaa Ramesh Kumar
- Vinícius Nascimento
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- Vishendran Govindasamy
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- Vukani T Manzini
- Vítor Miguel Pinho-Oliveira
- Wai Cheong Soon
- Wai Kit Jacky Chan
- Wangpin Xiao
- Warren Paul Kuhn
- Wei Ren
- Wei Xiao
- Weihong Zhao
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- Weilu Zhao
- Weiwei Zhang
- Weixing Wang
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- Wendy Joan Barrett
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- Wenhui Huang
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- Werner Schmid
- Weslley Mendes
- Widnyana Made Wid
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- Wilton van Klei
- Wing LamWong
- Wing Sze Li
- Wing Yan Lam
- Wiryana Made Wir
- Wolfgang Buhre
- Wolfgang Buhre
- Wujun Geng
- Xenia Souvatzis
- Xian-Jin Zhou
- Xianfu Lu
- Xiangming Fang
- Xianwen Hu
- Xiao Hong Wen
- Xiaocui Lv
- Xiaodong Ge
- Xiaodong Qiu
- Xiaoguang Zhang
- Xiaohua Zou
- Xiaolan Hu
- Xiaolin Zhang
- Xiaomao Zhu
- Xiaoqin Li
- Xiaoyan Zhang
- Xiaoying Li
- Xiaoying Zhao
- Xiaoyu Li
- Xiaoyun Shi
- Xiapei Xiong
- Xin He
- Xindan Du
- Xinjian Lu
- Xinmei Jiang
- Xinyu Qi
- Xiu-Li Wang
- Xiumei Song
- Xiuxiu Zhuang
- Xuewu Lin
- Xuming Hu
- Yan Jing
- Yan Leng
- Yan Pan
- Yan Zhang
- Yana Ilyina
- Yanbing Bi
- Yanfei Xia
- Yang Liu
- Yang Yang
- Yangwen Ou
- Yangyang Han
- Yanling Li
- Yanming Huang
- Yanqiu Ai
- Yapping Zhang
- Yaqi Li
- Yaqiu Chen
- Yassr Al-Soudaine
- Yavor Metodiev
- Yazhou Wen
- Yazhuo Yuan
- Ye Zhang
- Yelong Ren
- Yemi Adelaja
- Yetong Li
- Yew Ching Lee
- Yi Liu
- Yi Zhong
- Yi Zhu
- Yijiao Chen
- Yijun Chen
- Yik Lam Chan
- Ying Cao
- Yingfen Xiong
- Yingping Liang
- Yixiu Yan
- Yiyi Shi
- Yonghao Yu
- Yongjie Chen
- Yongqing Guo
- Yongtao Sun
- Yongzhong Tang
- Yoni van Duivenvoorde
- Youliang Tong
- Yousif Saeed
- Yousra Ahmad
- Yu Fan
- Yu Sun
- Yuan Hsuan Chang
- Yuan Liang Woon
- Yuan Zhang
- Yuanming Pan
- Yuanyuan Pan
- Yue Fei
- Yuehong Qi
- Yuejiang Liu
- Yuelan Wang
- Yugang Shi
- Yuhong Li
- Yuksel Gercek
- Yun Bai
- Yun Ren
- Yunbin Fu
- Yunchang Mo
- Yunfei Cai
- Yunlin Feng
- Yunzhi Ling
- Yurui Yao
- Yushio Cheing
- Yusuf Ameer
- Yuting Wang
- Yves Jaquet
- Yvonne Hack
- Yvonne Selibea
- Zaheer Moolla
- Zaid Makzal
- Zane Farina
- Zhang Chen
- Zhen Dan Peng
- Zhen Wang
- Zhen Wang
- Zheng Guo
- Zhengyuan Liu
- Zhenrong Ji
- Zhi Wang
- Zhipeng Wang
- Zhipeng Zhu
- Zhisong Li
- Zhiting Wen
- Zhong-Yuan Xia
- Zhongming Cao
- Zi-Ying Shen
- Zin Nico
- Ziqiang Miao
- Zoe Davies
- Zoe Drinkwater
- Zoe Whitman
- Zulkarnain Hamzah
- Álvaro Réa-Neto
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
This was an investigator initiated study funded by Nestle Health Sciences through an unrestricted research grant, and by a National Institute for Health Research (UK) Professorship held by RP. The study was sponsored by Queen Mary University of London
Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
- Author
- Aali Amirali
- Abbafati Cristiana
- Abbas Jaffar
- Abbasgholizadeh Rouzbeh
- Abbasi Madineh Akram
- Abbasian Mohammadreza
- Abd ElHafeez Samar
- Abd-Elsalam Sherief
- Abdelmasseh Michael
- Abdelwahab Ahmed
- Abdollahi Mohammad
- Abdoun Meriem
- Abdullahi Auwal
- Abdurehman Ame Mehadi
- Abebe Mesfin
- Abedi Aidin
- Abedi Armita
- Abegaz Tadesse M
- Abeldaño Zuñiga Roberto Ariel
- Abhilash E S
- Abiodun Olugbenga Olusola
- Aboagye Richard Gyan
- Abolhassani Hassan
- Abouzid Mohamed
- Abreu Lucas Guimarães
- Abrha Woldu Aberhe
- Abrigo Michael R M
- Abtahi Dariush
- Abu Rumeileh Samir
- Abu-Rmeileh Niveen ME
- Abu-Zaid Ahmed
- Aburuz Salahdein
- Acuna Juan Manuel
- Adair Tim
- Addo Isaac Yeboah
- Adebayo Oladimeji M
- Adegboye Oyelola A
- Adekanmbi Victor
- Aden Bashir
- Adepoju Abiola Victor
- Adetunji Charles Oluwaseun
- Adeyeoluwa Temitayo Esther
- Adeyomoye Olorunsola Israel
- Adha Rishan
- Adibi Amin
- Adikusuma Wirawan
- Adnani Qorinah Estiningtyas Sakilah
- Adra Saryia
- Afework Abel
- Afolabi Aanuoluwapo Adeyimika
- Afraz Ali
- Afyouni Shadi
- Afzal Saira
- Agasthi Pradyumna
- Aghamiri Shahin
- Agodi Antonella
- Agyemang-Duah Williams
- Ahinkorah Bright Opoku
- Ahmad Aqeel
- Ahmad Danish
- Ahmad Firdos
- Ahmad Muayyad M
- Ahmad Tauseef
- Ahmadi Keivan
- Ahmadzade Amir Mahmoud
- Ahmadzade Mohadese
- Ahmed Ayman
- Ahmed Haroon
- Ahmed Luai A
- Ahmed Muktar Beshir
- Ahmed Syed Anees
- Ajami Marjan
- Aji Budi
- Ajumobi Olufemi
- Akalu Gizachew Taddesse
- Akara Essona Matatom
- Akinosoglou Karolina
- Akkala Sreelatha
- Akyirem Samuel
- Al Hamad Hanadi
- Al Hasan Syed Mahfuz
- Al Homsi Ammar
- Al Qadire Mohammad
- AL-Ahdal Tareq Mohammed Ali
- Al-Aly Ziyad
- Al-amer Rasmieh Mustafa
- Al-Eyadhy Ayman
- Al-Gheethi Adel Ali Saeed
- Al-Hanawi Mohammed Khaled
- Al-Jumaily Adel
- Al-Marwani Sabah
- Al-Maweri Sadeq Ali Ali
- Al-Mekhlafi Hesham M
- Al-Sabah Salman Khalifah
- Al-Tawfiq Jaffar A
- Al-Worafi Yaser Mohammed
- Ala Moein
- Aladelusi Timothy Olukunle
- Alalalmeh Samer O
- Alam Khurshid
- Alam Manjurul
- Alam Zufishan
- Alanezi Fahad Mashhour
- Alanzi Turki M
- Albashtawy Mohammed
- AlBataineh Mohammad T
- Aldridge Robert W
- Alemi Sharifullah
- Alhabib Khalid F
- Alhalaiqa Fadwa Alhalaiqa Naji
- Ali Abid
- Ali Akhtar
- Ali Beriwan Abdulqadir
- Ali Hassam
- Ali Mohammed Usman
- Ali Rafat
- Ali Syed Shujait Shujait
- Ali Zahid
- Alian Samakkhah Shohreh
- Alicandro Gianfranco
- Alif Sheikh Mohammad
- Aligol Mohammad
- Alimi Rasoul
- Aliyi Ahmednur Adem
- Aljunid Syed Mohamed
- Almahmeed Wael
- Almazan Joseph Uy
- Almidani Omar
- Alomari Mahmoud A
- Alonso Nivaldo
- Alqahtani Jaber S
- Alqutaibi Ahmed Yaseen
- Altaf Awais
- Altirkawi Khalid A
- Alvi Farrukh Jawad
- Alwafi Hassan
- Aly Hany
- Alzoubi Karem H
- Amare Azmeraw T
- Ameyaw Edward Kwabena
- Amhare Abebe Feyissa
- Amin Tarek Tawfik
- Amindarolzarbi Alireza
- Aminian Dehkordi Javad
- Amiri Sohrab
- Amu Hubert
- Amugsi Dickson A
- Amzat Jimoh
- Ancuceanu Robert
- Anderlini Deanna
- Andrade Pedro Prata
- Andrei Catalina Liliana
- Andrei Tudorel
- Angappan Dhanalakshmi
- Anil Abhishek
- Anjum Afifa
- Antony Catherine M
- Antriyandarti Ernoiz
- Anuoluwa Iyadunni Adesola
- Anwar Sumadi Lukman
- Anyasodor Anayochukwu Edward
- Appiah Seth Christopher Yaw
- Aqeel Muhammad
- Arab-Zozani Morteza
- Arabloo Jalal
- Arabzadeh Bahri Razman
- Arafat Mosab
- Aravkin Aleksandr Y
- Araújo Ana Margarida
- Aremu Abdulfatai
- Ariffin Hany
- Aripov Timur
- Armocida Benedetta
- Arooj Mahwish
- Artamonov Anton A
- Artanti Kurnia Dwi
- Arulappan Judie
- Aruleba Idowu Thomas
- Aruleba Raphael Taiwo
- Arumugam Ashokan
- Asaad Malke
- Asgary Saeed
- Ashemo Mubarek Yesse
- Ashraf Muhammad
- Asika Marvellous O
- Athari Seyyed Shamsadin
- Atout Maha Moh'd Wahbi
- Atreya Alok
- Attia Sameh
- Aujayeb Avinash
- Avan Abolfazl
- Awotidebe Adedapo Wasiu
- Ayala Quintanilla Beatriz Paulina
- Ayanore Martin Amogre
- Ayele Getnet Melaku
- Ayuso-Mateos Jose L
- Ayyoubzadeh Seyed Mohammad
- Azadnajafabad Sina
- Azhar Gulrez Shah
- Aziz Shahkaar
- Azzam Ahmed Y
- Babashahi Mina
- Babu Abraham Samuel
- Badar Muhammad
- Badawi Alaa
- Badiye Ashish D
- Baghdadi Soroush
- Bagheri Nasser
- Bagherieh Sara
- Bah Sulaiman
- Bahadorikhalili Saeed
- Bai Jianjun
- Bai Ruhai
- Baker Jennifer L
- Bakkannavar Shankar M
- Bako Abdulaziz T
- Balakrishnan Senthilkumar
- Balogun Saliu A
- Baltatu Ovidiu Constantin
- Bam Kiran
- Banach Maciej
- Bandyopadhyay Soham
- Banik Biswajit
- Banik Palash Chandra
- Bansal Hansi
- Barati Shirin
- Barchitta Martina
- Bardhan Mainak
- Barker-Collo Suzanne Lyn
- Barone-Adesi Francesco
- Barqawi Hiba Jawdat
- Barr Ronald D
- Barrero Lope H
- Basharat Zarrin
- Bashir Asma'u I J
- Bashiru Hameed Akande
- Baskaran Pritish
- Basnyat Buddha
- Bassat Quique
- Basso João Diogo
- Basu Saurav
- Batra Kavita
- Batra Ravi
- Baune Bernhard T
- Bayati Mohsen
- Bayileyegn Nebiyou Simegnew
- Beaney Thomas
- Bedi Neeraj
- Begum Tahmina
- Behboudi Emad
- Behnoush Amir Hossein
- Beiranvand Maryam
- Bejarano Ramirez Diana Fernanda
- Belgaumi Uzma Iqbal
- Bell Michelle L
- Bello Aminu K
- Bello Muhammad Bashir
- Bello Olorunjuwon Omolaja
- Belo Luis
- Beloukas Apostolos
- Bendak Salaheddine
- Bennett Derrick A
- Bensenor Isabela M
- Benzian Habib
- Berezvai Zombor
- Berman Adam E
- Bermudez Amiel Nazer C
- Bettencourt Paulo J G
- Beyene Habtamu B
- Beyene Kebede A
- Bhagat Devidas S
- Bhagavathula Akshaya Srikanth
- Bhala Neeraj
- Bhalla Ashish
- Bhandari Dinesh
- Bhardwaj Nikha
- Bhardwaj Pankaj
- Bhardwaj Prarthna V
- Bhargava Ashish
- Bhaskar Sonu
- Bhat Vivek
- Bhatti Gurjit Kaur
- Bhatti Jasvinder Singh
- Bhatti Manpreet S
- Bhatti Rajbir
- Bhutta Zulfiqar A
- Bikbov Boris
- Binmadi Nada
- Bintoro Bagas Suryo
- Biondi Antonio
- Bisignano Catherine
- Bisulli Francesca
- Biswas Atanu
- Biswas Raaj Kishore
- Bitaraf Saeid
- Bjørge Tone
- Bleyer Archie
- Boampong Mary Sefa
- Bodolica Virginia
- Bodunrin Aadam Olalekan
- Bolarinwa Obasanjo Afolabi
- Bonakdar Hashemi Milad
- Bonny Aime
- Bora Basara Berrak
- Bora Kaustubh
- Borodo Safiya Bala
- Borschmann Rohan
- Botero Carvajal Alejandro
- Bouaoud Souad
- Boudalia Sofiane
- Boyko Edward J
- Bragazzi Nicola Luigi
- Braithwaite Dejana
- Brenner Hermann
- Britton Gabrielle
- Browne Annie J
- Brunoni Andre R
- Bulamu Norma B
- Bulto Lemma N
- Buonsenso Danilo
- Burkart Katrin
- Burns Richard A
- Burugina Nagaraja Sharath
- Busse Reinhard
- Bustanji Yasser
- Butt Zahid A
- Caetano dos Santos Florentino Luciano
- Cai Tianji
- Calina Daniela
- Campos Luciana Aparecida
- Campos-Nonato Ismael R
- Cao Chao
- Cardenas Carlos Alberto
- Carr Sinclair
- Carreras Giulia
- Carrero Juan J
- Carugno Andrea
- Carvalho Felix
- Carvalho Márcia
- Castaldelli-Maia Joao Mauricio
- Castañeda-Orjuela Carlos A
- Castelpietra Giulio
- Catalá-López Ferrán
- Catapano Alberico L
- Cattaruzza Maria Sofia
- Caye Arthur
- Cederroth Christopher R
- Cembranel Francieli
- Cenderadewi Muthia
- Cercy Kelly M
- Cerin Ester
- Cevik Muge
- Chacón-Uscamaita Pamela R Uscamaita
- Chahine Yaacoub
- Chakraborty Chiranjib
- Chan Jeffrey Shi Kai
- Chang Chin-Kuo
- Charalampous Periklis
- Charan Jaykaran
- Chattu Vijay Kumar
- Chatzimavridou-Grigoriadou Victoria
- Chavula Malizgani Paul
- Cheema Huzaifa Ahmad
- Chen An-Tian
- Chen Haowei
- Chen Lingxiao
- Chen Meng Xuan
- Chen Simiao
- Cherbuin Nicolas
- Chew Derek S
- Chi Gerald
- Chirinos-Caceres Jesus Lorenzo
- Chitheer Abdulaal
- Cho So Mi Jemma
- Cho William C S
- Chong Bryan
- Chopra Hitesh
- Choudhary Rahul
- Chowdhury Rajiv
- Chu Dinh-Toi
- Chukwu Isaac Sunday
- Chung Eric
- Chung Eunice
- Chung Sheng-Chia
- Cini Karly I
- Clark Cain C T
- Coberly Kaleb
- Columbus Alyssa
- Comfort Haley
- Conde Joao
- Conti Sara
- Cortesi Paolo Angelo
- Costa Vera Marisa
- Cousin Ewerton
- Cowden Richard G
- Criqui Michael H
- Cruz-Martins Natália
- Culbreth Garland T
- Cullen Patricia
- Cunningham Matthew
- Cámera Luis Alberto
- Cárdenas Rosario
- D'Amico Emanuele
- da Silva e Silva Daniel
- Dadana Sriharsha
- Dadras Omid
- Dai Zhaoli
- Dalal Koustuv
- Dalli Lachlan L
- Damiani Giovanni
- Daneshvar Sara
- Darwesh Aso Mohammad
- Das Jai K
- Das Saswati
- Dash Nihar Ranjan
- Dashti Mohsen
- Davis Weaver Nicole
- Davletov Kairat
- De Leo Diego
- Debele Aklilu Tamire
- Degenhardt Louisa
- Dehbandi Reza
- Deitesfeld Lee
- Delgado-Enciso Ivan
- Delgado-Ortiz Laura
- Demant Daniel
- Demessa Berecha Hundessa
- Demetriades Andreas K
- Deng Xinlei
- Denova-Gutiérrez Edgar
- Deribe Kebede
- Dervenis Nikolaos
- Des Jarlais Don C
- Desai Hardik Dineshbhai
- Desai Rupak
- Deuba Keshab
- Devanbu Vinoth Gnana Chellaiyan
- Dey Sourav
- Dhali Arkadeep
- Dhama Kuldeep
- Dhimal Mandira Lamichhane
- Dhimal Meghnath
- Dhingra Sameer
- Dias da Silva Diana
- Diaz Daniel
- Dima Adriana
- Ding Delaney D
- Dirac M Ashworth
- Dixit Abhinav
- Dixit Shilpi Gupta
- do Prado Camila Bruneli
- Do Thanh Chi
- Do Thao Huynh Phuong
- Dodangeh Masoud
- Dokova Klara Georgieva
- Dolecek Christiane
- Dorsey E Ray
- dos Santos Wendel Mombaque
- Doshi Rajkumar
- Doshmangir Leila
- Douiri Abdel
- Dowou Robert Kokou
- Driscoll Tim Robert
- Dsouza Haneil Larson
- Dube John
- Dumith Samuel C
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- Duraisamy Senbagam
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- Dutta Sulagna
- Dzianach Paulina Agnieszka
- Dziedzic Arkadiusz Marian
- Dávila-Cervantes Claudio Alberto
- Ebenezer Oluwakemi
- Eboreime Ejemai
- Ebrahimi Alireza
- Echieh Chidiebere Peter
- Ed-Dra Abdelaziz
- Edinur Hisham Atan
- Edvardsson David
- Edvardsson Kristina
- Efendi Defi
- Efendi Ferry
- Eghdami Shayan
- Eikemo Terje Andreas
- Eini Ebrahim
- Ekholuenetale Michael
- Ekpor Emmanuel
- Ekundayo Temitope Cyrus
- El Arab Rabie Adel
- El Morsi Doaa Abdel Wahab
- El Sayed Zaki Maysaa
- El Tantawi Maha
- Elbarazi Iffat
- Elemam Noha Mousaad
- Elgar Frank J
- Elgendy Islam Y
- ElGohary Ghada Metwally Tawfik
- Elhabashy Hala Rashad
- Elhadi Muhammed
- Elmeligy Omar Abdelsadek Abdou
- Elshaer Mohammed
- Elsohaby Ibrahim
- Emami Zeydi Amir
- Emamverdi Mehdi
- Emeto Theophilus I
- Engelbert Bain Luchuo
- Erkhembayar Ryenchindorj
- Eshetie Tesfahun C
- Eskandarieh Sharareh
- Espinosa-Montero Juan
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- Etaee Farshid
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- Saeed Umar
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- Safi Sare
- Sagar Rajesh
- Saghazadeh Amene
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- Shakil Husain
- Sham Sunder
- Shamim Muhammad Aaqib
- Shams-Beyranvand Mehran
- Shamshad Hina
- Shamshirgaran Mohammad Ali
- Shamsi Mohammad Anas
- Shanawaz Mohd
- Shankar Abhishek
- Sharfaei Sadaf
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- Weiss Daniel J
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- Wells Katherine M
- Wen Yi Feng
- Werdecker Andrea
- Westerman Ronny
- Wickramasinghe Dakshitha Praneeth
- Wickramasinghe Nuwan Darshana
- Wijeratne Tissa
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- Wojewodzic Marcin W
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- Wulandari Ratna Dwi
- Xiao Hong
- Xu Bin
- Xu Xiaoyue
- Yadav Lalit
- Yaghoubi Sajad
- Yang Lin
- Yano Yuichiro
- Yao Yao
- Ye Pengpeng
- Yesera Gesila Endashaw
- Yesodharan Renjulal
- Yesuf Subah Abderehim
- Yip Paul
- Yiğit Arzu
- Yiğit Vahit
- Yon Dong Keon
- Yonemoto Naohiro
- You Yuyi
- Younis Mustafa Z
- Yu Chuanhua
- Zadey Siddhesh
- Zadnik Vesna
- Zafari Nima
- Zahedi Mohammad
- Zahid Muhammad Nauman
- Zahir Mazyar
- Zakham Fathiah
- Zaki Nazar
- Zakzuk Josefina
- Zamagni Giulia
- Zaman Burhan Abdullah
- Zaman Sojib Bin
- Zamora Nelson
- Zand Ramin
- Zandi Milad
- Zandieh Ghazal G Z
- Zanghì Aurora
- Zare Iman
- Zastrozhin Mikhail Sergeevich
- Zeariya Mohammed G M
- Zeng Youjie
- Zhai Chunxia
- Zhang Chen
- Zhang Haijun
- Zhang Hongwei
- Zhang Yunquan
- Zhang Zhaofeng
- Zhang Zhenyu
- Zhao Hanqing
- Zhao Yang
- Zhao Yong
- Zheng Peng
- Zhong Chenwen
- Zhou Juexiao
- Zhu Bin
- Zhu Zhaohua
- Ziaeefar Pardis
- Zielińska Magdalena
- Zou Zhiyong
- Zumla Alimuddin
- Zweck Elric
- Zyoud Samer H
- Šekerija Mario
- Publication venue
- Elsevier
- Publication date
- 01/03/2024
- Field of study
BackgroundEstimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides new demographic estimates for 204 countries and territories and 811 additional subnational locations from 1950 to 2021, with a particular emphasis on changes in mortality and life expectancy that occurred during the 2020–21 COVID-19 pandemic period.Methods22 223 data sources from vital registration, sample registration, surveys, censuses, and other sources were used to estimate mortality, with a subset of these sources used exclusively to estimate excess mortality due to the COVID-19 pandemic. 2026 data sources were used for population estimation. Additional sources were used to estimate migration; the effects of the HIV epidemic; and demographic discontinuities due to conflicts, famines, natural disasters, and pandemics, which are used as inputs for estimating mortality and population. Spatiotemporal Gaussian process regression (ST-GPR) was used to generate under-5 mortality rates, which synthesised 30 763 location-years of vital registration and sample registration data, 1365 surveys and censuses, and 80 other sources. ST-GPR was also used to estimate adult mortality (between ages 15 and 59 years) based on information from 31 642 location-years of vital registration and sample registration data, 355 surveys and censuses, and 24 other sources. Estimates of child and adult mortality rates were then used to generate life tables with a relational model life table system. For countries with large HIV epidemics, life tables were adjusted using independent estimates of HIV-specific mortality generated via an epidemiological analysis of HIV prevalence surveys, antenatal clinic serosurveillance, and other data sources. Excess mortality due to the COVID-19 pandemic in 2020 and 2021 was determined by subtracting observed all-cause mortality (adjusted for late registration and mortality anomalies) from the mortality expected in the absence of the pandemic. Expected mortality was calculated based on historical trends using an ensemble of models. In location-years where all-cause mortality data were unavailable, we estimated excess mortality rates using a regression model with covariates pertaining to the pandemic. Population size was computed using a Bayesian hierarchical cohort component model. Life expectancy was calculated using age-specific mortality rates and standard demographic methods. Uncertainty intervals (UIs) were calculated for every metric using the 25th and 975th ordered values from a 1000-draw posterior distribution.FindingsGlobal all-cause mortality followed two distinct patterns over the study period: age-standardised mortality rates declined between 1950 and 2019 (a 62·8% [95% UI 60·5–65·1] decline), and increased during the COVID-19 pandemic period (2020–21; 5·1% [0·9–9·6] increase). In contrast with the overall reverse in mortality trends during the pandemic period, child mortality continued to decline, with 4·66 million (3·98–5·50) global deaths in children younger than 5 years in 2021 compared with 5·21 million (4·50–6·01) in 2019. An estimated 131 million (126–137) people died globally from all causes in 2020 and 2021 combined, of which 15·9 million (14·7–17·2) were due to the COVID-19 pandemic (measured by excess mortality, which includes deaths directly due to SARS-CoV-2 infection and those indirectly due to other social, economic, or behavioural changes associated with the pandemic). Excess mortality rates exceeded 150 deaths per 100 000 population during at least one year of the pandemic in 80 countries and territories, whereas 20 nations had a negative excess mortality rate in 2020 or 2021, indicating that all-cause mortality in these countries was lower during the pandemic than expected based on historical trends. Between 1950 and 2021, global life expectancy at birth increased by 22·7 years (20·8–24·8), from 49·0 years (46·7–51·3) to 71·7 years (70·9–72·5). Global life expectancy at birth declined by 1·6 years (1·0–2·2) between 2019 and 2021, reversing historical trends. An increase in life expectancy was only observed in 32 (15·7%) of 204 countries and territories between 2019 and 2021. The global population reached 7·89 billion (7·67–8·13) people in 2021, by which time 56 of 204 countries and territories had peaked and subsequently populations have declined. The largest proportion of population growth between 2020 and 2021 was in sub-Saharan Africa (39·5% [28·4–52·7]) and south Asia (26·3% [9·0–44·7]). From 2000 to 2021, the ratio of the population aged 65 years and older to the population aged younger than 15 years increased in 188 (92·2%) of 204 nations.InterpretationGlobal adult mortality rates markedly increased during the COVID-19 pandemic in 2020 and 2021, reversing past decreasing trends, while child mortality rates continued to decline, albeit more slowly than in earlier years. Although COVID-19 had a substantial impact on many demographic indicators during the first 2 years of the pandemic, overall global health progress over the 72 years evaluated has been profound, with considerable improvements in mortality and life expectancy. Additionally, we observed a deceleration of global population growth since 2017, despite steady or increasing growth in lower-income countries, combined with a continued global shift of population age structures towards older ages. These demographic changes will likely present future challenges to health systems, economies, and societies. The comprehensive demographic estimates reported here will enable researchers, policy makers, health practitioners, and other key stakeholders to better understand and address the profound changes that have occurred in the global health landscape following the first 2 years of the COVID-19 pandemic, and longer-term trends beyond the pandemic