15 research outputs found
Global Retinoblastoma Presentation and Analysis by National Income Level.
- Author
- Abdallah Elhassan
- Abdullahi Shehu U
- Abdulqader Rula A
- Adamou Boubacar Sahadatou
- Ademola-Popoola Dupe S
- Adio Adedayo
- Afshar Armin R
- Aggarwal Priyanka
- Aghaji Ada E
- Ahmad Alia
- Akib Marliyanti NR
- Al Ani Mouroge H
- Al Harby Lamis
- Al-Badri Safaa AF
- Al-Dahmash Saad A
- Al-Haddad Christiane
- Al-Hussaini Hamoud HY
- Al-Jadiry Mazin F
- Al-Jumaily Usama
- Al-Mafrachi Ali ARM
- Al-Shaheen Athar ASM
- Al-Shammary Entissar H
- Alakbarova Aygun
- Alcasabas Ana Patricia A
- Alejos Amanda
- Alemany-Rubio Ernesto
- Alfa Bio Amadou I
- Alfonso Carreras Yvania
- Ali Amany M
- Alia Donjeta B
- Alkatan Hind M
- All-Eriksson Charlotta
- Almeida Argentino A
- Alsawidi Khalifa M
- Amiruddin Primawita O
- Antonino Romanzo
- Astbury Nicholas J
- Atalay Hatice T
- Atchaneeyasakul La-Ongsri
- Atsiaya Rose
- Attaseth Taweevat
- Aung Than H
- Ayala Silvia
- Baizakova Baglan
- Balaguer Julia
- Balayeva Ruhengiz
- Balwierz Walentyna
- Barranco Honorio
- Bascaran Covadonga
- Beck Popovic Maja
- Benavides Raquel
- Benmiloud Sarra
- Bennani Guebessi Nissrine
- Berete Rokia C
- Berry Jesse L
- Bhaduri Anirban
- Bhat Sunil
- Biddulph Shelley J
- Biewald Eva M
- Bobrova Nadia
- Boehme Marianna
- Boldt HC
- Bonanomi Maria Teresa BC
- Bornfeld Norbert
- Bouda Gabrielle C
- Bouguila Hédi
- Boumedane Amaria
- Bowman Richard
- Brennan Rachel C
- Brichard Bénédicte G
- Buaboonnam Jassada
- Calderón-Sotelo Patricia
- Calle Jara Doris A
- Camuglia Jayne E
- Cano Miriam R
- Capra Michael
- Cassoux Nathalie
- Castela Guilherme
- Castillo Luis
- Català-Mora Jaume
- Chantada Guillermo L
- Chaudhry Shabana
- Chaugule Sonal S
- Chauhan Argudit
- Chawla Bhavna
- Chernodrinska Violeta S
- Chiwanga Faraja S
- Chuluunbat Tsengelmaa
- Cieslik Krzysztof
- Cockcroft Ruellyn L
- Comsa Codruta
- Correa Llano Maria G
- Correa Zelia M
- Corson Timothy W
- Cowan-Lyn Kristin E
- Csóka Monika
- Cui Xuehao
- Da Gama Isac V
- Dangboon Wantanee
- Das Anirban
- Das Sima
- Davanzo Jacquelyn M
- Davidson Alan
- De Potter Patrick
- Delgado Karina Q
- Demirci Hakan
- Desjardins Laurence
- Diaz Coronado Rosdali Y
- Dimaras Helen
- Dodgshun Andrew J
- Donaldson Craig
- Donato Macedo Carla R
- Dragomir Monica D
- Du Bruyn Magritha
- Du Yi
- Edison Kemala S
- Eka Sutyawan I Wayan
- El Kettani Asmaa
- Elbahi Amal M
- Elder James E
- Elgalaly Dina
- Elhaddad Alaa M
- Elhassan Moawia M Ali
- Elzembely Mahmoud M
- Essuman Vera A
- Evina Ted Grimbert A
- Fabian Ido Didi
- Fadoo Zehra
- Fandiño Adriana C
- Faranoush Mohammad
- Fasina Oluyemi
- Fernández Delia DPG
- Fernández-Teijeiro Ana
- Foster Allen
- Frenkel Shahar
- Fu Ligia D
- Fuentes-Alabi Soad L
- Gallie Brenda L
- Gandiwa Moira
- Garcia Pacheco Henry N
- Garcia Juan L
- García Aldana David
- Gassant Pascale Y
- Geel Jennifer A
- Ghassemi Fariba
- Girón Ana V
- Gizachew Zelalem
- Global Retinoblastoma Study Group
- Goenz Marco A
- Gold Aaron S
- Goldberg-Lavid Maya
- Gole Glen A
- Gomel Nir
- Gonzalez Perez Graciela
- Gonzalez Efren
- González-Rodríguez Liudmira
- Graells Jaime
- Green Liz
- Gregersen Pernille A
- Grigorovski Nathalia DAK
- Guedenon Koffi M
- Gunasekera D Sanjeeva
- Gupta Himika
- Gupta Sanjiv
- Gündüz Ahmet K
- Hadjistilianou Theodora
- Hamel Patrick
- Hamid Syed A
- Hamzah Norhafizah
- Hansen Eric D
- Harbour J William
- Hartnett M Elizabeth
- Hasanreisoglu Murat
- Hassan Sadiq
- Hassan Shadab
- Hederova Stanislava
- Hernandez Jose
- Hernandez Lorelay Marie Carcamo
- Hessissen Laila
- Hordofa Diriba F
- Huang Laura C
- Hubbard GB
- Hummlen Marlies
- Husakova Kristina
- Hussein Al-Janabi Allawi N
- Ida Russo
- Ilic Vesna R
- Jairaj Vivekaraj
- Jeeva Irfan
- Jenkinson Helen
- Ji Xunda
- Jo Dong Hyun
- Johnson Kenneth P
- Johnson William J
- Jones Michael M
- Kabesha Theophile B Amani
- Kabore Rolande L
- Kaliki Swathi
- Kalinaki Abubakar
- Kantar Mehmet
- Kao Ling-Yuh
- Kardava Tamar
- Kebudi Rejin
- Kepak Tomas
- Keren-Froim Naama
- Khan Zohora J
- Khaqan Hussain A
- Khauv Phara
- Kheir Wajiha J
- Khetan Vikas
- Khodabande Alireza
- Khotenashvili Zaza
- Kim Jeong Hun
- Kim Jonathan W
- Kiratli Hayyam
- Kivelä Tero T
- Klett Artur
- Komba Palet Jess Elio Kosh
- Krivaitiene Dalia
- Kruger Mariana
- Kulvichit Kittisak
- Kuntorini Mayasari W
- Kyara Alice
- Lachmann Eva S
- Lam Carol PS
- Lam Geoffrey C
- Larson Scott A
- Latinovic Slobodanka
- Laurenti Kelly D
- Le Bao Han A
- Lecuona Karin
- Leverant Amy A
- Li Cairui
- Limbu Ben
- Long Quah Boon
- Lukamba Robert M
- Lumbroso Livia
- Luna-Fineman Sandra
- Lutfi Delfitri
- Lysytsia Lesia
- López Juan P
- Magrath George N
- Mahajan Amita
- Majeed Abdul Rahim
- Maka Erika
- Makan Mayuri
- Makimbetov Emil K
- Manda Chatonda
- Martín Begue Nieves
- Mason John O
- Mason Lauren
- Matende Ibrahim O
- Materin Miguel
- Mattosinho Clarissa CDS
- Matua Marchelo
- Mayet Ismail
- Mbumba Freddy B
- McKenzie John D
- Medina-Sanson Aurora
- Mehrvar Azim
- Mengesha Aemero A
- Menon Vikas
- Mercado Gary John VD
- Mets Marilyn B
- Midena Edoardo
- Mishra Divyansh KC
- Mndeme Furahini G
- Mohamedani Ahmed A
- Mohammad Mona T
- Moll Annette C
- Montero Margarita M
- Morales Rosa A
- Moreira Claude
- Mruthyunjaya Prithvi
- Msina Mchikirwa S
- Msukwa Gerald
- Mudaliar Sangeeta S
- Muma Kangwa I
- Munier Francis L
- Murgoi Gabriela
- Murray Timothy G
- Musa Kareem O
- Mushtaq Asma
- Mustak Hamzah
- Muyen Okwen M
- Naidu Gita
- Nair Akshay Gopinathan
- Naumenko Larisa
- Ndoye Roth Paule Aïda
- Nency Yetty M
- Neroev Vladimir
- Ngo Hang
- Nieves Rosa M
- Nikitovic Marina
- Nkanga Elizabeth D
- Nkumbe Henry
- Nuruddin Murtuza
- Nyaywa Mutale
- Obono-Obiang Ghislaine
- Oguego Ngozi C
- Olechowski Andrzej
- Oliver Scott CN
- Osei-Bonsu Peter
- Ossandon Diego
- Paez-Escamilla Manuel A
- Pagarra Halimah
- Painter Sally L
- Paintsil Vivian
- Paiva Luisa
- Pal Bikramjit P
- Palanivelu Mahesh Shanmugam
- Papyan Ruzanna
- Parrozzani Raffaele
- Parulekar Manoj
- Pascual Morales Claudia R
- Paton Katherine E
- Pawinska-Wasikowska Katarzyna
- Pe'er Jacob
- Peric Sanja
- Peña Armando
- Pham Chau TM
- Philbert Remezo
- Plager David A
- Pochop Pavel
- Polania Rodrigo A
- Polyakov Vladimir G
- Pompe Manca T
- Pons Jonathan J
- Portabella Silvia Alarcón
- Prat Daphna
- Prom Vireak
- Purwanto Ignatius
- Qadir Ali O
- Qayyum Seema
- Qian Jiang
- Rahman Ardizal
- Rahman Salman
- Rahmat Jamalia
- Rajkarnikar Purnima
- Ramanjulu Rajesh
- Ramasubramanian Aparna
- Ramirez-Ortiz Marco A
- Raobela Léa
- Rashid Riffat
- Reddy M Ashwin
- Reich Ehud
- Renner Lorna A
- Reynders David
- Ribadu Dahiru
- Riheia Mussagy M
- Ritter-Sovinz Petra
- Rojanaporn Duangnate
- Romero Livia
- Roy Soma R
- Saab Raya H
- Saakyan Svetlana
- Sabhan Ahmed H
- Sagoo Mandeep S
- Said Azza MA
- Saiju Rohit
- Salas Beatriz
- San Román Pacheco Sonsoles
- Sayalith Phayvanh
- Scanlan Trish A
- Schefler Amy C
- Schoeman Judy
- Sedaghat Ahad
- Seregard Stefan
- Seth Rachna
- Shah Ankoor S
- Shakoor Shawkat A
- Sharma Manoj K
- Sherief Sadik T
- Shetye Nandan G
- Shields Carol L
- Siddiqui Sorath Noorani
- Sidi Cheikh Sidi
- Silva Sónia
- Singh Arun D
- Singh Niharika
- Singh Usha
- Singha Penny
- Sitorus Rita S
- Skalet Alison H
- Soebagjo Hendrian D
- Sorochynska Tetyana
- Ssali Grace
- Stacey Andrew W
- Staffieri Sandra E
- Stahl Erin D
- Stathopoulos Christina
- Stirn Kranjc Branka
- Stones David K
- Strahlendorf Caron
- Suarez Maria Estela Coleoni
- Sultana Sadia
- Sun Xiantao
- Sundy Meryl
- Superstein Rosanne
- Supriyadi Eddy
- Surukrattanaskul Supawan
- Suzuki Shigenobu
- Svojgr Karel
- Sylla Fatoumata
- Sánchez Gissela L
- Tamamyan Gevorg
- Tan Deborah
- Tandili Alketa
- Tarrillo Leiva Fanny F
- Tashvighi Maryam
- Tateshi Bekim
- Teh Kok Hoi
- Tehuteru Edi S
- Teixeira Luiz F
- Theophile Tuyisabe
- Toledano Helen
- Trang Doan L
- Traoré Fousseyni
- Trichaiyaporn Sumalin
- Tuncer Samuray
- Tyau-Tyau Harba
- Umar Ali B
- Unal Emel
- Uner Ogul E
- Urbak Steen F
- Ushakova Tatiana L
- Usmanov Rustam H
- Valeina Sandra
- van Hoefen Wijsard Milo
- Varadisai Adisai
- Vasquez Liliana
- Vaughan Leon O
- Veleva-Krasteva Nevyana V
- Verma Nishant
- Victor Andi A
- Viksnins Maris
- Villacís Chafla Edwin G
- Vishnevskia-Dai Vicktoria
- Vora Tushar
- Wachtel Antonio E
- Wackernagel Werner
- Waddell Keith
- Wade Patricia D
- Wali Amina H
- Wang Yi-Zhuo
- Weiss Avery
- Wilson Matthew W
- Wime Amelia DC
- Wiwatwongwana Atchareeya
- Wiwatwongwana Damrong
- Wolley Dod Charlotte
- Wongwai Phanthipha
- Xiang Daoman
- Xiao Yishuang
- Yam Jason C
- Yang Huasheng
- Yanga Jenny M
- Yaqub Muhammad A
- Yarovaya Vera A
- Yarovoy Andrey A
- Ye Huijing
- Yousef Yacoub A
- Yuliawati Putu
- Zapata López Arturo M
- Zein Ekhtelbenina
- Zhang Chengyue
- Zhang Yi
- Zhao Junyang
- Zheng Xiaoyu
- Zhilyaeva Katsiaryna
- Zia Nida
- Ziko Othman AO
- Zondervan Marcia
- Publication venue
- 'American Medical Association (AMA)'
- Publication date
- 01/01/2020
- Field of study
Importance: Early diagnosis of retinoblastoma, the most common intraocular cancer, can save both a child's life and vision. However, anecdotal evidence suggests that many children across the world are diagnosed late. To our knowledge, the clinical presentation of retinoblastoma has never been assessed on a global scale. Objectives: To report the retinoblastoma stage at diagnosis in patients across the world during a single year, to investigate associations between clinical variables and national income level, and to investigate risk factors for advanced disease at diagnosis. Design, Setting, and Participants: A total of 278 retinoblastoma treatment centers were recruited from June 2017 through December 2018 to participate in a cross-sectional analysis of treatment-naive patients with retinoblastoma who were diagnosed in 2017. Main Outcomes and Measures: Age at presentation, proportion of familial history of retinoblastoma, and tumor stage and metastasis. Results: The cohort included 4351 new patients from 153 countries; the median age at diagnosis was 30.5 (interquartile range, 18.3-45.9) months, and 1976 patients (45.4%) were female. Most patients (n = 3685 [84.7%]) were from low- and middle-income countries (LMICs). Globally, the most common indication for referral was leukocoria (n = 2638 [62.8%]), followed by strabismus (n = 429 [10.2%]) and proptosis (n = 309 [7.4%]). Patients from high-income countries (HICs) were diagnosed at a median age of 14.1 months, with 656 of 666 (98.5%) patients having intraocular retinoblastoma and 2 (0.3%) having metastasis. Patients from low-income countries were diagnosed at a median age of 30.5 months, with 256 of 521 (49.1%) having extraocular retinoblastoma and 94 of 498 (18.9%) having metastasis. Lower national income level was associated with older presentation age, higher proportion of locally advanced disease and distant metastasis, and smaller proportion of familial history of retinoblastoma. Advanced disease at diagnosis was more common in LMICs even after adjusting for age (odds ratio for low-income countries vs upper-middle-income countries and HICs, 17.92 [95% CI, 12.94-24.80], and for lower-middle-income countries vs upper-middle-income countries and HICs, 5.74 [95% CI, 4.30-7.68]). Conclusions and Relevance: This study is estimated to have included more than half of all new retinoblastoma cases worldwide in 2017. Children from LMICs, where the main global retinoblastoma burden lies, presented at an older age with more advanced disease and demonstrated a smaller proportion of familial history of retinoblastoma, likely because many do not reach a childbearing age. Given that retinoblastoma is curable, these data are concerning and mandate intervention at national and international levels. Further studies are needed to investigate factors, other than age at presentation, that may be associated with advanced disease in LMICs
Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world
- Author
- Abad Pedro
- Abbara Suhny
- Abbasi Taimur
- Abbott Brian
- Abdel Aziz Islam Shawky
- Abdulla Jawdat
- Abikhzer Gad
- Abohashem Shady
- Abougabal Mahasen
- Abramson Sandra
- Abrihan Paz
- Acuña Arturo Romero
- Affandi Erwin
- Afzal Muhammad Shehzad
- Agolti Mariela
- Agranovich Svetlana
- Aguadé-Bruix Santiago
- Aguero Roberto Nicolas
- Ahmed Hassan Mohamed Ismail
- Ahmed Taghreed
- Akhter Afroza
- Al Dhuhli Humoud
- Al Kindi Faiza
- Al-Abboud Tarek
- Al-Bulushi Naeema
- Al-Mallah Mouaz
- Alak Maria del Carmen
- Alam Edison
- Alaoui Nadia Ismaili
- Alasnag Mirvat
- Albadr Amjed
- Albalooshi Batool
- Albano Domenico
- Alberguina Lucia Graciela
- Albernaz Siqueira Maria Helena
- Alexanderson-Rosas Erick
- Alfaro Ana
- Ali Mohamed Mandour
- Alkadhi Hatem
- Alkandari Faridah
- Allam Adel
- Allarakha Mohammad Aaftaab
- Almeida Augusto
- Almousalli Omar
- Alongi Pierpaolo
- Alonso Omar
- Alves Togni Paulo Henrique
- Alves Wilson Furlan
- Ananthasubramaniam Karthikeyan
- Anderson Jill
- Andrade Jose Henrique
- Andrade Luciana
- Angelidis George
- Anselmi Carlos
- Ansheles Alexey
- Araújo Roberta
- Archontaki Aikaterini
- Arnone Gaspare
- Arnous Samer
- Arnson Yoav
- Arroñada Guillermo
- Arturo Harold
- Asano Hiroshi
- Ascani Sebastian Perez
- Asfour Ahmed
- Askew Jeffrey
- Assadi Majid
- Astesiano Alfredo
- Astesiano Andrea
- Attanasio Lea
- Atyani Said
- Ayala Sandra
- Ayetey Harold
- Ayodele Tolulope
- Azevedo Guilherme
- Bagatin Elisa
- Bailly Matthieu
- Baldari Sergio
- Balmer-Swain Mallory
- Bang Ji-In
- Banthia Nilesh
- Bar-Shalom Rachel
- Barette Rene
- Baric Ana
- Barneveld Peter
- Barragan Adriana Puente
- Barragan Erika
- Barroso Asela
- Basavaraj Ashok Gangasandra
- Batinic Tonci
- Batista Juan Felipe
- Batyrkhanov Daultai
- Bauckneht Matteo
- Baugh Dainia
- Bayer Richard R.
- Bedi Punit
- Bejai Shereen
- Ben-Rais Nozha
- Benedek Imre
- Benedek Theodora
- Benitez Luis
- Benlabgaa Rabie
- Bennie George
- Benteo Pablo
- Beretta Mario
- Berman Daniel S.
- Bernheim Adam
- Bertelli Paolo
- Bester Ria
- Bettencourt Nuno
- Better Nathan
- Better Nathan
- Beuzeville Scott
- Bezerra Sabbrina
- Bhagat Jinendra Kumar
- Bhargava Rishi
- Bhat Vivek
- Bhatia Mona
- Bhatti Sabha
- Biancardi Rodrigo
- Bianco Francesco
- Bieging Erik
- Biggans Thomas
- Bittencourt Marcio Sommer
- Blanco Isabel
- Blanco Juan
- Blankstein Ron
- Blankstein Ron
- Bloom Stephen
- Blue Sean
- Bluemke David
- Bluemke David A.
- Boktor Raef
- Bom Henry
- Bonelli Juan Manuel
- Bonfiglioli Rachele
- Boni Roberto
- Borges Andressa
- Bouyoucef Salah
- Branch Kelley
- Brandão Simone
- Bravo Paco
- Brothers Jessica
- Bruno Andrea
- Bruno Isabella
- Bråten Anders Tjellaug
- Budoff Matthew
- Buechel Ronny Ralf
- Buga Klara
- Bularga Anda
- Bull Russell
- Bullock-Palmer Renée
- Burandt Angela
- Burg Samuel
- Burger Peter
- Burgul Rajesh
- Burke Floyd W.
- Bush Kelvin
- Busnardo Elena
- Bustos Jose Javier
- Butler Patrick
- Byrne Angela
- Bøttcher Morten
- Cabada Manuel
- Cabeda Estevan Vieira
- Cabrejas Raul
- Cabrera Antonio
- Cachero Jorge
- Cadena Alberto
- Caicedo Carlos
- Calcott Jennifer
- Califaretti Elena
- Camarero Alicia
- Camoni Luca
- Campisi Roxana
- Canal Maria Pedrera
- Candela Candace
- Canderoli Alejandro
- Canessa Jose
- Cantinho Guilhermina
- Cao Dianbo
- Capasso Elizabeth
- Carames Silvia
- Carnevale Aldo
- Carpenter John-Paul
- Carr Loretta
- Carrascosa Patrícia
- Carreira Lara
- Carvajal-Juarez Isabel
- Casoni Roberta
- Castro Bruno
- Castro Gabriel
- Castro Ricardo
- Casáns-Tormo Irene
- Cavalcante Joao
- Cavallo Armando Ugo
- Cavenaghi Giorgio
- Cendoya Oscar
- Cerci Rodrigo
- Cerci Rodrigo J.
- Ceriani Luca
- Chambers Duane
- Chan Virgil
- Chang Donald
- Chang Tien
- Chao Charles
- Chatterjee Saurav
- Chatziioannou Sofia
- Chatzizisis Yiannis
- Cheezum Michael
- Chen Jennifer
- Chen Marcus
- Chen Tiffany
- Cheung Stephen
- Chierichetti Franca
- Chimura Chimura Misato
- Chiocchi Marcello
- Cho Sang-Geon
- Choi Andrew
- Choi Andrew
- Choi Andrew D.
- Chong Woon
- Choudhury Partha
- Chow Benjamin
- Chowdekar Vijay Sai
- Christensen Mette
- Cittanti Corrado
- Clarcq James
- Cognigni Luciano Martin
- Cohen Yosef
- Cohen Yosef A.
- Coie Tchoyoson Lim
- Coles Duncan
- Collaud Carlos
- Collaud Carlos
- Colletta Mauro
- Concha Carmen
- Conti Umberto
- Cordero Ayreen
- Cortes Claudia
- Cortés Filiberto
- Cortés Violeta
- Cossu Alberto
- Courtis Javier
- Cragnolino Daniel
- Crim Matthew
- Cruz Eric
- Cuadra Teresa
- Cuellar-Calabria Hug
- Cunali Fernando
- Cuocolo Alberto
- Cury Roberto
- Cusack David
- Cuzzocrea Marco
- Dabreo Dominique
- Dai Xu
- Daicz Mariana
- Danciu Sorin
- Dantas Roberto
- Dariy Olga
- Datseris Ioannis
- Dautov Tairkhan
- de Amorim Fernandes Fernando
- De Boeck Bart
- De Carvalho Filipe Penna
- De La Peña Erasmo
- De La Vega Alejandro
- De Lorenzo Andrea
- De Macedo Filho Robson
- De Maria Silvia Teresa
- De Rimini Maria Luisa
- De Souza Thiago Ferreira
- De Vincentis Giuseppe
- Decter Bruce
- Del Giudice Eleonora
- Del Riego Horacio
- Del Torto Alberico
- Della Tommasina Veronica
- Deshpande Aparna
- Dettori Fernando
- Deux Jean-François
- Deviggiano Alejandro
- Dhruva Nimish
- Diaz Javier Lopez
- Djuraev Omoa
- Dobson Mark
- Doherty Neil
- Dondi Maurizio
- Dondi Maurizio
- Dorbala Sharmila
- Dorbala Sharmila
- Dougan John
- Doukky Rami
- Downie D'Arne
- Dragonetti Laura
- Drozdova Olga
- Dunbar Anjori
- Durmo Rexhep
- Duvall William
- Dwivedi Girish
- Edmond John
- Edwards Rachael
- Efros-Monsen Elen
- Einstein Andrew J.
- Einstein Andrew J.
- Elison Barry
- Ellis Chris
- Emami Farshad
- Embon Mario
- Engela Jean
- Engelbrecht Gerrit
- Engelmann Vaclav
- Enriquez Ruben Emilio
- Ensinas Jorge
- Erba Paola Anna
- Erthal Fernanda
- Escobar Manuel Valencia
- Escorza Velez Giovanni Alejandro
- Espeche Maria del Huerto Velazquez
- Esquitin Kerry
- Evangelista Laura
- Evbuomwan Osayande
- Faccio Fernando
- Facello Adolfo
- Fairbairn Timothy
- Faletti Riccardo
- Faragasso Evelina
- Faraggi Marc
- Farah Husam
- Farrugia Alexia
- Farsad Mohsen
- Fatima Shazia
- Fentanes Emilio
- Ferencik Maros
- Ferencik Maros
- Fernandes Fabio
- Fernandes Fabio
- Fernandes Juliano
- Ferrando Rodolfo
- Ferreira Antonio
- Ferro Paola
- Feuchtner Gudrun
- Fisher Daniel
- Fitzpatrick Daniel
- Flores Ana Camila
- Florimonte Luigia
- Flotats Albert
- Forsdahl Signe Helene
- Foster Cameron
- Fragkaki Christina
- Franceschi Maja
- Francis Roslyn
- Frantellizzi Viviana
- Frenkel Alex
- Friedrich Matthias
- Fringuelli Fabio Massimo
- Fuentes Cañamero Maria Eugenia
- Fuisz Tony
- Fujimoto Shinichiro
- Fujisue Koichiro
- Fukunaga Tomohisa
- Fukushima Yoshimitsu
- Fukuyama Kae
- Gagarina Nina
- Gaikwad Anand
- Gama-Moreno Manlio
- Gamboa Isabel Berrocal
- Gannon Michael
- Garai Ildiko
- Garashi Masoud
- Garcheva-Tsacheva Marina
- García María Elia
- Garg Ria
- Garofalo Diego
- Gastner Lori
- Gatti Marco
- Gaudiano Angela
- Georgoulias Panagiotis
- Geronazzo Ricardo
- Gerson Myron
- Gheysens Olivier
- Ghimire Ram Kumar
- Ghini Bruno
- Ghoshhajra Brian
- Gimelli Alessia
- Girijanandan Mahapatra Prof Dr
- Giubbini Raffaele
- Giuffrida Francesca
- Glaudemans Andor
- Gleeson Tadhg
- Goda Artan
- Goebel Benjamin
- Goebel Benjamin
- Goldberg Alan
- Goldner Brian
- Gomez Marie Rhiamar
- Gomez Sharon
- Goncalves Luiz
- Gong Lianggeng
- Gongxeka Harlem
- Gonza Natalia
- Gonzalez Carla
- Gonzalez Jorge
- González Luis
- González Ulises
- González-Montecinos Alejandro Becerril
- Goodwin Bruce
- Gopalan Deepa
- Gore Rosco
- Gormsen Lars Christian
- Gottlieb Ilan
- Gracia-López Sandra
- Greenough Robert
- Grossman Gabriel Blacher
- Gräni Christoph
- Gulyaev Vsevolod Milyevich
- Gummow Alistair
- Gunawan Gani
- Gutierrez Villamil Claudia T.
- Gutierrez Goleat
- Gutierrez Lucas
- Gutierrez Yamile Marcos
- Gutierrez Yamile Marcos
- Guzzo Miguel Angel
- Guzzo Miguel Angel
- Gómez Lauchy Juan Manuel
- Habets Jesse
- Habouzit Vincent
- Hadlich Marcelo
- Hafez Mohammed Nassoh
- Hage Fadi
- Haidar Mohamad
- Haider Agha
- Haider Sofia
- Hamilton Mark
- Hamilton-Craig Christian
- Hamirani Yasmin
- Han Dan
- Hapkido Habusari
- Harbinson Mark
- Hartley Thomas
- Hasbak Philip
- Hasbani Victor
- Hashimoto Jun
- Hassan Alia
- Hassan Mona
- Hassen Karen
- Hatfield Mallory
- Hawkins Carolyn
- Hawthorne Katie
- Heath Nicholas
- Hendel Robert
- Hernandez Phillip
- Hernández Gertrudis Sabatel
- Herrera Yariela
- Hess Søren
- Hidalgo Pablo
- Hidayat Basuki
- Hildre Dimmen Jenni-Mari
- Hill Gregory
- Hinterleitner Gerd
- Hirschfeld Cole B.
- Hirschfeld Cole B.
- Holdgaard Paw
- Homans Filip
- Hong Chae Moon
- Horgan Stephen
- Hou Yang
- Houshmand Golnaz
- Hsieh Victar
- Hua Shaw
- Huda Aulia
- Hudson Benjamin
- Huerin Melina
- Huffman Jeff
- Hurwitz Lynne
- Hyafil Fabien
- Ialuna Salvatore
- Ibrahim Ahmed
- Ichikawa Yasutaka
- Iguchi Nobuo
- Iii George Kinzfogl
- Ilic Srdja
- Imai Masamichi
- Inaki Anri
- Irodi Aparna
- Ishimura Hayato
- Iskandrian Ami
- Isobe Satoshi
- Issoufou Djibrillou Moussa
- Itskovich Irina
- Jaimes Claudia
- Jain Shashank
- Janardhanan Rajesh
- Jang Su Jin
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- Jawa Zabah
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- Kaffas Sameh
- Kalinin Artem
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- Kalra Dinesh
- Kamani Christel H.
- Kameoka Vinícius
- Kaminek Milan
- Kandeel Ahmed
- Kang Won Jun
- Kapitan Miguel
- Kaplan Mitchell
- Karalkin Anatoly
- Karim Noor Khairiah A.
- Kato Takao
- Kaviratne Summanther
- Kawel-Boehm Nadine
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- Kay Michael
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- Lee Kenneth
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- Leipsic Jonathon
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- Leta Rubén
- Leung Eugene
- Leung Steve
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- Liguori Carlo
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- Liu Hui
- Liu Jinkang
- Liu Yiyan
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- Londoño Juan
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- Lopes Rafael Willain
- Lopez-Mattei Juan
- Lopez-Mattei Juan
- Lopez-Mattei Juan
- Lotti Jose Maria
- Louw Lizette
- Lovera Cesar
- Low Chen
- Lu Bin
- Lu Bin
- Lu Yao
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- Luna Hiram Rivera
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- Marcassa Claudio
- Markowitz Jeremy
- Marn Amanda
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- Marquez Alejandra
- Marquez-Cabeza Juan Javier
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- Martin Jon
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- Masoli Osvaldo
- Masoli Osvaldo Horacio
- Massardo Teresa
- Mastrocola Luiz Eduardo
- Mastrovito Edgardo
- Mataciunas Mindaugas
- Mataki Hiroyuki
- Matis Stephen E.
- Matos Luis
- Matushita Cristina Sebastião
- Maurice Hany
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- Mele Anibal
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- Meneghetti José Claudio
- Menezes de Siqueira Maria Eduarda
- Menezes Leon
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- Merani Maria Fernanda
- Meretta Alejandro Horacio
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- Moncayo Antonio Calderón
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- Mor Maya
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- Morelos Martha
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- Morimoto Ryota
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- Nakata Tomoaki
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- Napier Kyle
- Nardi Barbara
- Narula Jagat
- Narula Jagat
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- Naue Vania
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- Nolasco Roberto
- Nomura Cesar
- Norgaard Bjarne Linde
- Norikane Takashi
- Norton Carolina Bas
- Novoa Carlos
- Nunura Felix
- Nørgaard Bjarne Linde
- O'Brien Julie
- O'Rourke Edward
- O'Sullivan Patricia
- Obaldo Jerry
- Occleshaw Christopher
- Ohta Yasutoshi
- Oikonomou Anastasia
- Okarvi Subhani
- Okayama Satoshi
- Okizaki Atsutaka
- Oliveira Joao Bruno
- Ombati Kevin
- Onimode Yetunde
- Ornelas Mario
- Ortellado José
- Ortga Ramirez Jose Alberto
- Osman Medhat
- Otomi Yoichi
- Otsuka Hideki
- Ozair Ahmad
- Paar Maja Hrabak
- Pabon Luz
- Pacella Sara
- Padma Savenadia
- Paez Diana
- Paez Diana
- Paixao Eduardo
- Panagidis Christoforos
- Pandos George
- Parwani Purvi
- Parwani Purvi
- Parwani Purvi
- Pascual Thomas N. B.
- Pascual Thomas N. B.
- Pasquet Agnès
- Passen Edward
- Pastrana Davidson
- Patel Amit
- Patel Chetan
- Patel Dilip
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- Pineda Mauricio
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- Porter Thomas
- Pospelov Viktor
- Possetti Priscila
- Poulter Rohan
- Prawiro Djoko
- Preciado-Anaya Andrés
- Preciado-Gutiérrez Óscar Ulises
- Premaratne Manuja
- Premprabha Teerapon
- Prentice Ryan
- Prior David
- Prior John O.
- Probst Stephan
- Proffit Franck
- Prpic Marina
- Pubul-Nuñez Virginia
- Pugliese Francesca
- Pujol Maria Paula
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- Punda Ante
- Pursnani Amit
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- Pynda Yaroslav
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- Quinon Alvin
- Quinta Mayra
- Rabbat Mark
- Radzinschi Alejandro
- Raggi Paolo
- Raggi Paolo
- Raimondi Gustavo
- Rajbanshi Bijoy
- Rajvong Sonexay
- Ramamurti Suresh
- Ramkumar Prasad Guntur
- Rampin Lucia
- Ramírez Nelsy Gonzalez
- Randazzo Michael
- Randazzo Michael J.
- Ranser Sara
- Rawashdeh Mohammad
- Rayo Madrid Juan Ignacio
- Redruello Marcela
- Regaieg Hamza
- Reichmuth Luise
- Repasos Evangelos
- Rey Cristina Rodríguez
- Riaz Musab
- Ricci Fabrizio
- Rich Florence
- Ridley Lloyd
- Robinson Austin
- Robles Kim
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- Rochela Luis
- Rodrigues Alfredo
- Rodrigues Carlos
- Rodriguez Daniel Calderon
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- Roelants Veronique
- Rofe Christopher
- Roifman Idan
- Rojas Juan Carlos
- Romantini Leila
- Romero Romina Lorena
- Rominger Axel
- Roque Vanegas Hector Bladimir
- Rorie Mark
- Rosales Uvera Sandra Graciela
- Rossini Pierluigi
- Rostami Maryam Tajik
- Rovaletti Federico
- Rozikhodjaeva Gulnora
- Rubini Giuseppe
- Ruiz Diego
- Ruiz Joaquín
- Rumberger John
- Russell Raymond
- Russo Vincenzo
- Rutherford Natalie
- Ryzhkova Daria
- Ríos Raúl Araujo
- Rønnow Sand Niels Peter
- Saadullah Mohammad
- Sabharwal Nikant
- Sabra Philip
- Sacchetti Gian Mauro
- Sadler Diego
- Saifullina Guzaliya
- Saito Masaki
- Sakanyan Mari
- Sakata Sakata Yasushi
- Salehi Hamid
- Salobir Barbara Gužic
- Sambuceti Gianmario
- Samuel Anthony
- San Miguel Lucas
- Sanches Adelina
- Sandoval Sigelinda
- Santana Sara
- Sara da Silva Leonardo
- Sarai Masayoshi
- Saranovic Dragana Sobic
- Sarda-Mantel Laure
- Sasse Alexander
- Sato Daisuke
- Satyr Maryna
- Saunders Connor
- Saxena Sudhir
- Sayman Haluk
- Sazonova Svetlana
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- Scarlett Luke
- Schemmer Mary
- Schmidt Erzsébet
- Schneider Roman P.
- Schoepf U. Joseph
- Schofield Rebecca
- Scholte Arthur
- Scholtens Asbjørn
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- Schvartzman Paulo
- Sciagrà Roberto
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- Sekar Ramkumar
- Sellem Ali
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- Sengupta Shantanu
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- Sergienko Vladimir
- Sergienko Vladimir
- Sevilla Ana
- Shaaban Mahmoud
- Shah Nishant
- Shah Nishant R.
- Shah Samir
- Shalev Aryeh
- Shanbhag Sujata
- Sharma Gaurav
- Sharma Naveen
- Shaw Leslee J.
- Shaw Leslee J.
- Shayani Steven
- Shetty Deepa
- Shiozaki Afonso
- Shiraishi Shinya
- Shirani Jamshid
- Shirka Ervina
- Shivaram Pushpa
- Shrestha Ganesh
- Shulman Jonathan
- Shurupova Irina
- Sierra-Galan Lilia M.
- Sierra-Galan Lilia M.
- Sigman Steven
- Silva Fábio Martins
- Simanek Milan
- Simon Mitch
- Simonsson Magnus
- Singh Bhanupriya
- Singh Santosh
- Sinitsyn Valentin
- Siqueira Cristiano
- Siu Silvia
- Slart Riemer
- Slim Ahmad
- Small Gary
- Smanio Paola
- Smith Alexandra
- Smith David
- So Young
- Soares Carlos Eduardo
- Soeriadi Erwin Affandi
- Solanki Vijay
- Solari Lucrecia
- Soldat-Stankovic Valentina
- Soli Idrissa Adamou
- Soman Prem
- Sood Aditya
- Sood Ashwani
- Sperandio Massimiliano
- Spiro Bernardo
- Srichai-Parsia Monvadi Barbara
- Stan Claudiu Adrian
- Stankovic Sinisa
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- Stavrou Petros
- Stefanelli Antonella
- Steffensen Rolf
- Strada Bruno
- Streeter James
- Strouhal Peter
- Stuart Murch
- Stubbs Michael
- Subedi Deepak
- Sueldo Claudio Pereyra
- Sun Kai
- Suwa Yoshinobu
- Swainson Ian
- Syawaluddin Hilman
- Syed Ghulam
- Szilveszter Balint
- T Albert
- Tacher Vania
- Tag Naima
- Takanami Kentaro
- Takehana Kazuya
- Taki Junichi
- Taleb Sara
- Tamaki Nagara
- Tandon Vikas
- Tang Gongshun
- Tang Jeanelle Margareth
- Taniguchi Yasuyo
- Taubman Kim
- Tawakol Ahmed
- Taylor Andrew
- Tecson Bettina
- Teragawa Hiroki
- Theng Youdaline
- Thientunyakit Tanyaluck
- Thimister Paul
- Thomas Dustin
- Thomas Paul
- Thomassen Anders
- Thompson Randall
- Thu Phyo Si
- To Andrew
- Tomas Miguel Santaularia
- Tomizawa Nobuo
- Topping William
- Torbet Tara
- Torreao Jorge
- Torres Rafael
- Traverso Sonia
- Traverzo Sonia Simona
- Trifonova Tatjana
- Trinidad Desiree
- Trivedi Adwait
- Tsujita Kenichi
- Tweed Katharine
- Udugama Chandraguptha
- Uellendahl Marly
- Ullery Shawn
- Umeji Kyoko
- Unger Steven
- Unzek Samuel
- Upton Anthony
- Uretsky Seth
- Uson Kristine Joy
- Ussov Wladimir Yurievich
- Uusitalo Valtteri
- Uy Mila
- Vajauskas Donatas
- Vakhromeeva Margarita
- Valiullina Nailya
- Vallejo Enrique
- Valles Mario
- Vallurupalli Srikanth
- Vallée Jean-Paul
- Valsamaki Pipitsa
- Vamadevan Shankar
- Van Asperen Erik-Jan
- Van De Heyning Caroline M.
- Van Gaal William
- Van Pelt Niels
- Vangu Mboyo
- Vargas Luis Salazar
- Vasquez Andres
- Vavlukis Marija
- Velez Mayra Sanchez
- Veltman Niels
- Ventroni Guido
- Vergel Damiana
- Verjans Johan
- Verma Atul
- Verma Vikas
- Verschure Derk
- Veríssimo Otávia
- Villines Todd C.
- Villines Todd C.
- Vitola Joao V.
- Vitola Joao V.
- Vondrak Andrej
- Voutnis Demetrius
- Vuuren Magritha Jv
- Várady Edit
- Vázquez Manuel Castillo
- Wagenaar Nils
- Wakabayashi Yasushi
- Waller Alfonso
- Waltrick Roberto
- Wang Ellen
- Wang Jian
- Wang Ximing
- Wang Yifan
- Wang Yining
- Wang Zhao-Qian
- Ward Parker
- Wayne Victor
- Weihmuller Juan Sebastian
- Weir-Mccall Jonathan
- Weiss Konrad
- Weissman Gaby
- Wesbey George
- White James
- White Kelly
- Williams Michelle C.
- Williams Michelle C.
- Wilson Peter
- Winchester David
- Winchester David
- Wolcan Juan
- Wolinsky David
- Won Kyoung Sook
- Wong David
- Wong Kirby
- Wu Jiang
- Wu Zhifang
- Xia Liming
- Xiao Jiangxi
- Xu Lei
- Xu Zhuoran
- Yamada Shinichiro
- Yamazaki Shinya
- Yang Youyou
- Yew Min Sen
- Yin Wu
- Yoneyama Tatsuya
- Yost Sandra
- Young Calum
- Younger John
- Younis Muhammad Numair
- Yu Jianqun
- Yuan Li
- Zaid Eed Abu
- Zakavi Seyed Rasoul
- Zapparoli Marcello
- Zavadovsky Konstantin
- Zeffiro Susana
- Zeidán Nahla
- Zerahn Bo
- Zgaljardic Michael
- Zhang Longjiang
- Zhang Tong
- Zhang Xiaoli
- Zhang Yong-Gao
- Zhu Li
- Zhuravlev Kirill
- Zoboli Stefania
- Zukotynski Katherine
- Zuluaga Alejandro
- Øvrehus Kristian Altern
- Štalc Monika
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic.
Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality.
Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States.
Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis.
Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection
The genetic architecture of the human cerebral cortex
- Author
- Adams Hieab H H
- Adams Hieab H H
- Agartz Ingrid
- Ahlijanian Michael
- Ahmad Shahzad
- Ainscough Susan
- Aisen Paul
- Albers Colleen S
- Albert Marilyn
- Alhusaini Saud
- Allard Joanne
- Almeida Marcio A A
- Alnæs Dag
- Alvim Marina K M
- Ames David
- Ames David
- Amin Najaf
- Amlien Inge K
- Amouyel Philippe
- Ances Beau
- Anderson Karen
- Anderson Tim J
- Andersson Micael
- Andreassen Ole A
- Andreassen Ole A
- Apostolova Liana
- Ard Tyler
- Arias-Vasquez Alejandro
- Armstrong Nicola J
- Armstrong Nicola J
- Arnedo Vanessa
- Arnold Steven E
- Artiges Eric
- Artiges Eric
- Ashley-Koch Allison
- Assaly Michele
- Assareh Amelia A
- Asthana Sanjay
- Atkins Joshua R
- Aydin Semiha
- Ayesa-Arriola Rosa
- Baca Marne
- Bachman David
- Banaschewski Tobias
- Barbot Alexis
- Barker Gareth
- Barone Paolo
- Bartha Rob
- Bartzokis George
- Bastin Mark E
- Bastin Mark E
- Bates Vernice
- Baune Bernhard T
- Becerra Mauricio
- Becker Andreas
- Becker James T
- Beckett Laurel
- Beckham Jean C
- Beiser Alexa S
- Belden Christine M
- Belger Aysenil
- Bell Karen L
- Berg Daniela
- Bergman Howard
- Bernard Manon
- Bernard Manon
- Bernick Charles
- Bernstein Matthew
- Beyer Frauke
- Bezivin-Frere Pauline
- Biondo Francesca
- Bis Joshua C
- Bis Joshua C
- Bishop Courtney
- Black Sandra
- Blangero John
- Blank Karen
- Bodge Courtney
- Bokde Arun
- Bonakdarpour Borna
- Boomsma Dorret I
- Borges-Neto Salvador
- Borowski Bret
- Borrie Michael
- Bralten Janita
- Brand Connie
- Brandabur Melanie
- Brandt Christine L
- Brewer James
- Brockington John
- Brodaty Henry
- Brodaty Henry
- Bromberg Uli
- Brooks David
- Brooks William M
- Brosch Jared R
- Brouwer Rachel M
- Brown Gregory G
- Bruehl Ruediger
- Brunner Han G
- Buckholtz Neil
- Buckner Randy L
- Budson Andrew E
- Buimer Elizabeth E L
- Buitelaar Jan K
- Burke Anna
- Burns Jeffrey M
- Bustillo Juan R
- Bülow Robin
- Bülow Robin
- Bürger Christian
- Bÿchel Christian
- Cabrera Yuliana
- Cahn Wiepke
- Cairns Murray J
- Cairns Nigel J
- Calhoun Vince
- Cannon Dara M
- Capote Horacio
- Carlsson Cynthia M
- Carmichael Owen
- Carr Vaughan J
- Carrillo Maria
- Carroll Maria
- Carson Richard E
- Carter Raina
- Casaceli Cynthia
- Casalin Paola
- Caseras Xavier
- Caspell Chelsea
- Caspers Svenja
- Catafau Ana
- Cavalleri Gianpiero L
- Cedarbaum Jesse
- Cellar Janet S
- Celmins Dzintra
- Cendes Fernando
- Chahine Lama
- Chakravarty Mallar
- Chalker Alison
- Chao Steven
- Chen Kewei
- Chen Qiang
- Chertkow Howard
- Cheung Joshua W
- Chiang Gloria
- Ching Christopher R K
- Chowdhury Munir
- Chowdhury Sohini
- Chu Congying
- Cichon Sven
- Clark Christopher M
- Clark David
- Coffey Christopher
- Coleman Edward
- Colodro-Conde Lucía
- Comery Thomas
- Conrad Gary
- Conrod Patricia
- Consortium CHARGE
- Consortium Enhancing NeuroImaging Genetics through Meta-Analysis
- Consortium EPIGEN
- Consortium IMAGEN
- Consortium SYS
- Correia Stephen
- Corvin Aiden
- Couvy-Duchesne Baptiste
- Crawford Karen
- Creech Mary L
- Crespo-Facorro Benedicto
- Crivello Fabrice
- Curran Joanne E
- D'Agostino Daniel
- Daedelow Laura
- Daiello Lori A
- Dale Anders M
- Dale Anders M
- Dalley Jeffrey
- Dalrymple-Alford John C
- Dalvie Shareefa
- Dang Mimi
- Dannlowski Udo
- Darin Abigail
- Davies Gareth E
- Davies Peter
- de Araujo Tânia K
- de Geus Eco J C
- de Zubicaray Greig I
- de Zwarte Sonja M C
- Deary Ian J
- Deary Ian J
- Debette Stephanie
- Debette Stephanie
- Decarli Charles
- DeCarli Charles
- Deeley Cheryl
- Degenhardt Franziska
- Delanty Norman
- DeMarco Kathryn
- den Braber Anouk
- Dennis Michelle F
- Depondt Chantal
- Desrivieres Sylvane
- Desrivières Sylvane
- Dietsche Bruno
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- Ing Alex
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- Iranzo Alex
- Isaacson Stuart
- Isensee Corinna
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- Ittermann Bernd
- Jack Clifford R
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- Jennings Danna
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- Jian Xueqiu
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- Jicha Greg
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- Johnson Nancy
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- Kikuchi Masataka
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- Lee Virginia
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- Lenahan Art
- Leonard Gabriel
- Lerner Alan
- Lethbridge Emma
- Lett Tristram A
- Leverenz James
- Levey Allan I
- Lewis Lindsay
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- Meyer-Lindenberg Andreas
- Michie Patricia T
- Milaneschi Yuri
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- Walter Henrik
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- Wardlaw Joanna M
- Weber Bernd
- Weinberger Daniel R
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- Weiner Michael W
- Weintraub Sandra
- Wen Wei
- Wen Wei
- Westlye Lars T
- Whelan Christopher D
- Whelan Robert
- Whelan Robert
- White Tonya
- Willeke Diana
- Williams Karen
- Williams Steve
- Wilson Renee
- Winkfield David
- Witbracht Megan
- Witt Stephanie H
- Witte A Veronica
- Wittfeld Katharina
- Wittfeld Katharina
- Wolf Christiane
- Wolfers Thomas
- Wolk David A
- Womack Kyle
- Wong Terence Z
- Woo Ellen
- Wright Margaret J
- Wright Margaret J
- Wu Chuang-Kuo
- Wu Jing Qin
- Wurster Isabel
- Xia Rui
- Yamamori Hidenaga
- Yanez Beatriz
- Yang Mia
- Yang Qiong
- Yang Qiong
- Yankey Jon
- Yasuda Clarissa L
- Yeh Randy
- Yesavage Jerome
- Zamrini Edward
- Zare Habil
- Zaremba Dario
- Zhang Zuo
- Zhou Juan
- Zhu Alyssa H
- Zimmerman Earl A
- Ziolkowski Jaimie
- Zsembik Leo C P
- Zwiers Marcel P
- Publication venue
- 'American Association for the Advancement of Science (AAAS)'
- Publication date
- 01/01/2020
- Field of study
The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, we conducted a genome-wide association meta-analysis of brain magnetic resonance imaging data from 51,665 individuals. We analyzed the surface area and average thickness of the whole cortex and 34 regions with known functional specializations. We identified 199 significant loci and found significant enrichment for loci influencing total surface area within regulatory elements that are active during prenatal cortical development, supporting the radial unit hypothesis. Loci that affect regional surface area cluster near genes in Wnt signaling pathways, which influence progenitor expansion and areal identity. Variation in cortical structure is genetically correlated with cognitive function, Parkinson's disease, insomnia, depression, neuroticism, and attention deficit hyperactivity disorder
The global retinoblastoma outcome study : a prospective, cluster-based analysis of 4064 patients from 149 countries
- Author
- Abdallah Elhassan
- Abdullahi Shehu U.
- Abdulqader Rula A.
- Abdulrahaman Aminatu A.
- Abouelnaga Sherif
- Ademola-Popoola Dupe S.
- Adio Adedayo
- Afifi Mahmoud A.
- Afshar Armin R.
- Aggarwal Priyanka
- Aghaji Ada E.
- Ahmad Alia
- Akib Indonesia Marliyanti N.R.
- Akinsete Adeseye
- Al Ani Mouroge H.
- Al Harby Lamis
- Al Mesfer Saleh
- Al-Badri Safaa A.F.
- Al-Dahmash Saad A.
- Al-Haddad Christiane E.
- Al-Hussaini Hamoud H.Y.
- Al-Jadiry Mazin F.
- Al-Janabi Allawi N. Hussein
- Al-Jumaily Usama
- Al-Mafrachi Ali A.R.M.
- Al-Shaheen Athar A.S.M.
- Al-Shammary Entissar H.
- Alcasabas Ana Patricia A.
- Aldana David Garcia
- Alejos Amanda
- Alemany-Rubio Ernesto
- Alfa Bio Amadou I.
- Ali Amany M.
- Alia Donjeta B.
- Alkatan Hind M.
- All-Eriksson Charlotta
- Almeida Argentino A.
- Alsawidi Khalifa M.
- Amankwaa-Frempong Doreen
- Amiruddin Primawita O.
- Anchaya Jacqueline Karina Vasquez
- Armytasari Inggar
- Astbury Nicholas J.
- Atalay Hatice T.
- Atchaneeyasakul La-ongsri
- Atsiaya Rose
- Autrata Rudolf
- Balaguer Julia
- Balayeva Ruhengiz
- Barranco Honorio
- Bartoszek Paulina
- Bartuma Katarina
- Bascaran Covadonga
- Bechrakis Nikolaos E.
- Begimkulova Ainura S.
- Benmiloud Sarra
- Berete Rokia C.
- Berry Jesse L.
- Bhaduri Anirban
- Bhat Sunil
- Bhattacharyya Arpita
- Biewald Eva M.
- Binkley Elaine
- Blum Sharon
- Bobrova Nadia
- Boldt H.C.
- Bonanomi Maria Teresa B.C.
- Bouda Gabrielle C.
- Bouguila Hedi
- Bowman Richard
- Bowman Richard
- Brennan Rachel C.
- Brichard Benedicte G.
- Buaboonnam Jassada
- Budiongo Aleine
- Burton Matthew J.
- Calderon-Sotelo Patricia
- Calvo Jesus Peralta
- Camuglia Jayne E.
- Cano Miriam R.
- Capra Michael
- Carreras Yvania Alfonso
- Caspi Shani
- Cassoux Nathalie
- Castela Guilherme
- Castillo Luis
- Catala-Mora Jaume
- Cavieres Isabel
- Chafla Edwin G. Villacis
- Chandramohan Arthika
- Chantada Guillermo L.
- Chantada Guillermo L.
- Chantada Guillermo L.
- Chaudhry Shabana
- Chawla Bhavna
- Chen Wensi
- Chiwanga Faraja S.
- Chuluunbat Tsengelmaa
- Cieslik Krzysztof
- Clark Antony
- Cockcroft Ruellyn L.
- Comsa Codruta
- Coronado Rosdali Y. Díaz
- Corson Timothy W.
- Couitchere Line
- Cowan-Lyn Kristin E.
- Csoka Monika
- Dangboon Wantanee
- Das Anirban
- Das Pranab
- Das Sima
- Davanzo Jacquelyn M.
- Davidson Alan
- De Francesco Sonia
- De Potter Patrick
- Demirci Hakan
- Desjardins Laurence
- Dimaras Helen
- Dod Charlotte Wolley
- Dodgshun Andrew J.
- Dragomir Monica D.
- Du Bruyn Magritha
- Du Plessis Johannes
- Du Yi
- Dudeja Gagan
- Eerme Katrin
- El Kettani Asmaa
- Elbahi Amal M.
- Elder James E.
- Elhaddad Alaa M.
- Elhassan Moawia M.A.
- Elzembely M.
- Ericksen Connor
- Essuman Vera A.
- Evina Ted Grimbert A.
- Ezegwui Ifeoma R.
- Fabian Ido Didi
- Fabian Ido Didi
- Fadoo Zehra
- Fandiño Adriana C.
- Faranoush Mohammad
- Fasina Oluyemi
- Fernandez Delia D.P.G.
- Fernandez-Teijeiro Ana
- Foster Allen
- Frenkel Shahar
- Fu Ligia D.
- Fuentes-Alabi Soad L.
- Garcia Juan L.
- Geel Jennifer A.
- Ghassemi Fariba
- Giron Ana V.
- Goenz Marco A.
- Gold Aaron S.
- Goldberg Hila
- Gomel Nir
- Gonzalez Efren
- Gonzalez-Rodriguez Liudmira
- Gopinathan Nair Akshay
- Gorfine Malka
- Graells Jaime
- Gregersen Pernille A.
- Grigorovski Nathalia D.A.K.
- Groznik Alenka Lavric
- Guedenon Koffi M.
- Gunasekera D. Sanjeeva
- Gupta Himika
- Gupta Sanjiv
- Gupta Vineeta
- Gündüz Ahmet K.
- Hadjistilianou Theodora
- Hamel Patrick
- Hamid Syed A.
- Hamzah Norhafizah
- Hansen Eric D.
- Harbour William
- Hartnett M. Elizabeth
- Hasanreisoglu Murat
- Hassan Muhammad
- Hassan Sadiq
- Hassan Shadab
- Hautz Wojciech
- Haydar Huda
- Hederova Stanislava
- Hessissen Laila
- Hongeng Suradej
- Hordofa Diriba F.
- Hubbard G. Baker
- Hummelen Marlies
- Husakova Kristina
- Ibanga Affiong
- Ida Russo
- Ilic Vesna R.
- Islamia Ispahani
- Islamov Ziyavuddin
- Jairaj Vivekaraj
- Jara Doris A. Calle
- Jeeva Irfan
- Ji Xunda
- Jo Dong Hyun
- Jones Michael M.
- Kabesha Amani Theophile B.
- Kabore Rolande L.
- Kaliki Swathi
- Kalinaki Abubakar
- Kamsang Pius
- Kapelushnik Noa
- Kardava Tamar
- Kebudi Rejin
- Keomisy Jonny
- Kepak Tomas
- Ketteler Petra
- Khan Zohora
- Khaqan Hussain A.
- Khetan Vikas
- Khodabande Alireza
- Khotenashvili Zaza
- Kim Jeong Hun
- Kim Jonathan W.
- Kiratli Hayyam
- Kivela Tero T.
- Klett Artur
- Kosh Komba Palet Jess Elio
- Ko~ Irem
- Krivaitiene Dalia
- Kruger Mariana
- Kulvichit Kittisak
- Kuntorini Mayasari W.
- Kyara Alice
- Lam Geoffrey C.
- Larson Scott A.
- Latinovic Slobodanka
- Laurenti Kelly D.
- Lavy Yotam
- Leiva Fanny F. Tarrillo
- Leverant Amy A.
- Li Cairui
- Li Kaijun
- Limbu Ben
- Liu Chun-Hsiu
- Llano Maria G. Correa
- Lopez Arturo M. Zapata
- Lopez Juan P.
- Lukamba Robert M.
- Luna-Fineman Sandra
- Lutfi Delfitri
- Lysytsia Lesia
- Macedo Carla R. Donato
- Madgar Shiran
- Magrath George N.
- Mahajan Amita
- Maitra Puja
- Maka Erika
- Makimbetov Emil K.
- Maktabi Azza
- Maldonado Carlos
- Mallipatna Ashwin
- Manudhane Rebecca
- Manzhuova Lyazat
- Martin-Begue Nieves
- Masud Sidra
- Matende Ibrahim O.
- Mattosinho Clarissa C.D.S.
- Matua Marchelo
- Mayet Ismail
- Mbumba Freddy B.
- McKenzie John D.
- Mehrvar Azim
- Mengesha Aemero A.
- Menon Vikas
- Mercado Gary John V.
- Mets Marilyn B.
- Midena Edoardo
- Midena Edoardo
- Miller Audra
- Mishra Divyansh K.C.
- Mndeme Furahini G.
- Mohamedani Ahmed A.
- Mohammad Mona T.
- Moll Annette C.
- Montero Margarita M.
- Morales Claudia R. Pascual
- Moreira Claude
- Mruthyunjaya Prithvi
- Msina Mchikirwa S.
- Msukwa Gerald
- Mudaliar Sangeeta S.
- Muma Kangwa I.M.
- Munier Francis L.
- Murray Timothy G.
- Musa Kareem O.
- Mushtaq Asma
- Musika Anne A.
- Mustak Hamzah
- Mustapha Tajudeen
- Muyen Okwen M.
- Myezo Khumo H.
- Naidu Gita
- Naidu Natasha
- Nair Akshay Gopinathan
- Natarajan Sundaram
- Naumenko Larisa
- Nency Yetty M.
- Neroev Vladimir
- Ng Yvonne
- Nikitovic Marina
- Nkanga Elizabeth D.
- Nkumbe Henry E.
- Numbi Marcel N.
- Nummi Kalle
- Nuruddin Murtuza
- Nyaywa Mutale
- Nyirenda Chinsisi
- Obono-Obiang Ghislaine
- Oliver Scott C .
- Oporto Joaquin
- Orozco Alma Janeth Sanchez
- Ortega-Hernández Miriam
- Oscar Alexander H.
- Ossandon Diego
- Pacheco Henry N. Garcia
- Pacheco Sonsoles San Roman
- Paintsil Vivian
- Paiva Luisa
- Palanivelu Mahesh Shanmugam
- Papyan Ruzanna
- Parrozzani Raffaele
- Paton Katherine E.
- Perez Graciela Gonzalez
- Peric Sanja
- Pe’er Jacob
- Pham Chau T.M.
- Philbert Remezo
- Plager David A.
- Pochop Pavel
- Polania Rodrigo A.
- Polyakov Vladimir
- Pompe Manca Tekavcic
- Ponce Jimena
- Popovic Maja Beck
- Portabella Silvia Alarcon
- Qadir Ali O.
- Qayyum Seema
- Qian Jiang
- Quah BoonLong
- Quintero D Karina
- Rahman Ardizal
- Rajkarnikar Purnima
- Ramanjulu Rajesh
- Ramasubramanian Aparna
- Ramirez-Ortiz Marco A.
- Randhawa Jasmeen K.
- Randrianarisoa Hoby Lalaina
- Raobela Lea
- Rashid Riffat
- Reddy M. Ashwin
- Refaeli David
- Renner Lorna A.
- Reynders David
- Ribadu Dahiru
- Ritter-Sovinz Petra
- Rogowska Anna
- Rojanaporn Duangnate
- Romero Livia
- Roth Paule Aida Ndoye
- Roy Soma R.
- Saab Raya H.
- Saakyan Svetlana
- Sabhan Ahmed H.
- Sagoo Mandeep S.
- Said Azza M.A.
- Saiju Rohit
- Salas Beatriz
- Sanchez Gissela L.
- Sayalith Phayvanh
- Scanlan Trish A.
- Schluter Sabrina
- Schwab Christoph
- Sedaghat Ahad
- Seth Rachna
- Sgroi Mariana
- Shah Ankoor S.
- Shakoor Shawkat A.
- Sharma Manoj K.
- Sherief Sadik T.
- Shields Carol L.
- Sia David
- Siddiqui Sorath Noorani
- Sidi cheikh Sidi
- Silva Sonia
- Singh Arun D.
- Singh Usha
- Singha Penny
- Sitorus Rita S.
- Skalet Alison H.
- Soebagjo Hendrian D.
- Sorochynska Tetyana
- Ssali Grace
- Stacey Andrew W.
- Staffieri Sandra E.
- Stahl Erin D.
- Steinberg David M.
- Stones David K.
- Strahlendorf Caron
- Suarez Maria Estela Coleoni
- Sultana Sadia
- Sun Xiantao
- Superstein Rosanne
- Supriyadi Eddy
- Surukrattanaskul Supawan
- Sutyawan I. Wayan Eka
- Suzuki Shigenobu
- Svojgr Karel
- Sylla Fatoumata
- Tamamyan Gevorg
- Tan Deborah
- Tandili Alketa
- Tang Jing
- Tashvighi Maryam
- Tateshi Bekim
- Teh Kok Hoi
- Tehuteru Edi S.
- Teixeira Luiz F.
- Thawaba Abdullah Dahan M.
- Theophile Tuyisabe
- Toledano Helen
- Trang Doan L.
- Traore Fousseyni
- Tripathy Devjyoti
- Tuncer Samuray
- Tyau-Tyau Harba
- Umar Ali B.
- Unal Emel
- Uner Ogul E.
- Urbak Steen F.
- Ushakova Tatiana L.
- Usmanov Rustam H.
- Valeina Sandra
- Valente Paola
- Van Hoefen Wijsard Milo
- Vaughan Leon O.
- Veleva-Krasteva Nevyana V.
- Verma Nishant
- Victor Andi A.
- Viksnins Maris
- Villegas Victor M.
- Vishnevskia-Dai Victoria
- Waddell Keith
- Wali Amina H.
- Wang Yi-Zhuo
- Wangtiraumnuay Nutsuchar
- Wetter Julie
- Widiarti Widiarti
- Wilson Matthew W.
- Wime Amelia D.C.
- Wiwatwongwana Atchareeya
- Wiwatwongwana Damrong
- Wong Emily S.
- Wongwai Phanthipha
- Wu Si-qi
- Xiang Daoman
- Xiao Yishuang
- Xu Bing
- Xue Kang
- Yaghy Antonio
- Yam Jason C.
- Yang Huasheng
- Yanga Jenny M.
- Yarovaya Vera A.
- Yarovoy Andrey A.
- Ye Huijing
- Yee Roberto I.
- Yousef Yacoub A.
- Yuliawati Putu
- Zein Ekhtelbenina
- Zhang Yi
- Zhilyaeva Katsiaryna
- Zia Nida
- Ziko Othman A.O.
- Zondervan Marcia
- Publication venue
- Elsevier
- Publication date
- 23/08/2022
- Field of study
DATA SHARING : The study data will become available online once all analyses are complete.BACKGROUND : Retinoblastoma is the most common intraocular cancer worldwide. There is some evidence to suggest that major differences exist in treatment outcomes for children with retinoblastoma from different regions, but these differences have not been assessed on a global scale. We aimed to report 3-year outcomes for children with retinoblastoma globally and to investigate factors associated with survival. METHODS : We did a prospective cluster-based analysis of treatment-naive patients with retinoblastoma who were diagnosed between Jan 1, 2017, and Dec 31, 2017, then treated and followed up for 3 years. Patients were recruited from 260 specialised treatment centres worldwide. Data were obtained from participating centres on primary and additional treatments, duration of follow-up, metastasis, eye globe salvage, and survival outcome. We analysed time to death and time to enucleation with Cox regression models. FINDINGS : The cohort included 4064 children from 149 countries. The median age at diagnosis was 23·2 months (IQR 11·0–36·5). Extraocular tumour spread (cT4 of the cTNMH classification) at diagnosis was reported in five (0·8%) of 636 children from high-income countries, 55 (5·4%) of 1027 children from upper-middle-income countries, 342 (19·7%) of 1738 children from lower-middle-income countries, and 196 (42·9%) of 457 children from low-income countries. Enucleation surgery was available for all children and intravenous chemotherapy was available for 4014 (98·8%) of 4064 children. The 3-year survival rate was 99·5% (95% CI 98·8–100·0) for children from high-income countries, 91·2% (89·5–93·0) for children from upper-middle-income countries, 80·3% (78·3–82·3) for children from lower-middle-income countries, and 57·3% (52·1-63·0) for children from low-income countries. On analysis, independent factors for worse survival were residence in low-income countries compared to high-income countries (hazard ratio 16·67; 95% CI 4·76–50·00), cT4 advanced tumour compared to cT1 (8·98; 4·44–18·18), and older age at diagnosis in children up to 3 years (1·38 per year; 1·23–1·56). For children aged 3–7 years, the mortality risk decreased slightly (p=0·0104 for the change in slope). INTERPRETATION : This study, estimated to include approximately half of all new retinoblastoma cases worldwide in 2017, shows profound inequity in survival of children depending on the national income level of their country of residence. In high-income countries, death from retinoblastoma is rare, whereas in low-income countries estimated 3-year survival is just over 50%. Although essential treatments are available in nearly all countries, early diagnosis and treatment in low-income countries are key to improving survival outcomes.The Queen Elizabeth Diamond Jubilee Trust and the Wellcome Trust.https://www.thelancet.com/journals/langlo/homeam2023Paediatrics and Child Healt
Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19
- Author
- ?ivko Iris
- Abbass Hakam
- Abdeladim Lilia
- Abdelhady Hesham
- Abdelkharim Hussam
- Abdelrazik Marwa
- Abdi Zakee
- Abdukahil Sheryl Ann
- Abel Lynn
- Abraham Jacinta
- Abrahamson Gail
- Abusamra Yousuf
- Aceto Romina
- Adams Nick
- Adams Peter
- Adebambo Olumide
- Adhikari Neill
- Adhikari Sheetal
- Affleck Julia
- Agha Gloria
- Aghemo Alessio
- Agno Ronan
- Ahmad Norfaizan
- Ain Quratul
- Ainscough Kate
- Ainsworth James
- Aitken Lindianne
- Akamp Ceren
- Al Enezi Farhan
- Al-Bassam Wisam
- Al-Beidh Farah
- Albert Martin
- Albrett Jonathan
- Alderman Meera
- Aldo Bonizzoni Matteo
- Alegria Ana
- Alessandro Carà Gianmarco
- Alexander Brian
- Alexander Peter
- Alfonso Jordan
- Ali Maryam
- Ali Murtaza
- Allam Hayat
- Allen Barbara
- Allen Louise
- Allibone Suzanne
- Almeshhedani Hasham
- AlQahtani Samah
- Alswaidan Lolowa
- Altomy Mohammed
- Al Amri Ali
- Al Qasim Eman
- Amatya Sameena
- Ambrosino Richard
- Anderson Thomas
- Andreae Mark
- Aneman Anders
- Angus Derek C.
- Anjum Aisha
- Ankert Juliane
- Annane Djillali
- Anne-Laure Fedou
- Anstey Matthew
- Antcliffe David
- Anthony Alpha
- Antoine Marchalot
- Antoine Pierre
- Antoine Studer
- Anumakonda Vikram
- Aparicio Christelle
- Aquino Maia
- Arabi Yaseen M.
- Arachchige Malka
- Aravindan Latha
- Arbane Gill
- Archambault Patrick
- Archer Simon
- Aref Noah
- Arias Ana-Marie
- Arias Sonia
- Arishi Hatim
- Arnold Donald
- Arnold John
- Arnott Andrew
- Arora Anand
- Aryal Diptesh
- Asghar Adeeba
- Asif Namra
- Aspinwall Angelique
- Attokaran Antony
- Attwood Ben
- Au Carly
- Audry Mathilde
- Austin Karen
- Austin Pauline
- Auvet Adrien
- Avard Bronwyn
- Awan Sidra
- Ayee Robert
- Azaiz Amine
- Azzaui Harun
- Babu Suresh
- Bacon Gina
- Badalamenti Salvatore
- Badie Julio
- Bagavathy Kavitha
- Bagot Catherine
- Bagshaw Sean
- Baig Nadia
- Baikady Ravishankar
- Bailey Lucy
- Baillie Kenneth
- Bain William
- Baker Alice
- Baker Evelyn
- Baker Stuart
- Bakthavatsalam Dhanalakshmi
- Balaie Morteza
- Balls-Burgess Sam
- Bamford Amy
- Bamford Peter
- Banach Dorota
- Bannard-Smith Jonathan
- Barbash Ian
- Barber Russell
- Barbier François
- Barge Deborah
- Bariola Ryan
- Barker Gareth
- Barker Stephanie
- Barnes Nicky
- Baron Rebecca M.
- Barreau Amelie
- Barreau Amélie
- Bart Robert
- Bartholomew Jazz
- Bartley Shauna
- Barton David
- Barton Frances
- Bashyal Archana
- Basile Kim
- Bass Frances
- Bassford Christopher
- Bastos Joana Margarida Pereira Sousa
- Bates Michelle
- Bates Samantha
- Batista Teresa Margarida Oliveira
- Bauchmuller Kris
- Bayne Madeleine
- Bean Sarah
- Beane Abi
- Beane Abigail
- Beard Gregory
- Beasley Richard
- Beaudoin Rosalie
- Beavis Sarah
- Beddows Seonaid
- Bedford Caroline
- Beer Deborah
- Beer Sally
- Begin Phillipe
- Begum Salma
- Bell Gillian
- Bellemare David
- Belletti Allesandro
- Bendjemar Lynda
- Benettaib Fatna
- Bensen Nicole
- Bentley Andrew
- Benyon Sarah
- Benzekri Dalila
- Beqai Besa
- Berdaguer Fernando
- Beresford Stephanie
- Bergin Colin
- Berry Lindsay R.
- Berry Scott
- Berryman Emily
- Bertel Melanie
- Best-Lane Janis
- Besten Henny
- Bevan Emily
- Bewley Jeremy
- Beyerl Ashley
- Bhagani Sanjay
- Bhandal Khushpreet
- Bharaj Kiranjit
- Bhattarai Bina
- Bhattarai Binita
- Bhonagiri Deepak
- Biddie Simon
- Bigas Judit
- Bihari Shailesh
- Bin Hasan Mohd Shahnaz
- Bindels Manon
- Binnie Alexandra
- Biradar Vishwanath
- Birch Catherine
- Birch Janine
- Birch Sophie
- Birchall Kathrine
- Birkinshaw Isobel
- Black Ethel
- Blackledge Bethany
- Blakemore Hayley
- Blanck Wendy
- Bland Yvonne
- Blank Elisabeth
- Bleasdale John
- Bloomfield Jack
- Bloos Frank
- Board Jasmin
- Boardman Melanie
- Boari Gianluca
- Bocher Simon
- Bociek Aneta
- Boivin Anne-Helene
- Boivin Anne-Hélène
- Bojunga Jörg
- Bomken Charlotte
- Bonaccorso Allesandra
- Bongaerts Katherine
- Bonner Stephen
- Bonten Marc J. M.
- Borgatta Barbara
- Borislavova Borislava
- Borrill Zoe
- Boschert Catherine
- Bossard Isabelle
- Bothma Pieter
- Boudineau Michel
- Boulanger Marie-Claude
- Boumahni Dounia
- Bouman Angela
- Bounab Rania
- Bourgoin Charlotte
- Bourne Michelle
- Bourne Richard
- Boutin Mireille
- Bouvier Elodie
- Bouw-Ruiter Marianne
- Boué Yvonnick
- Bowen James
- Bowler Helen
- Boyd Craig
- Boyles Rebecca
- Bracke Stephanie
- Bradbury Charlotte A.
- Bradley Paul
- Brady Kara
- Brailsford Jane
- Brain Matthew
- Brakké Karen
- Brant Emily
- Brasselet Aurélie
- Breen Patrick
- Bremmer Pamela
- Brend Morwenna
- Brennan Aoife
- Bretagnol Anne
- Brett Stephen
- Brewer Chris
- Brickell Kathy
- Bridges Sarah
- Brieger Klaus-Gerd
- Brightling Chris
- Brimfield Lutece
- Brittain Michael
- Britton Kate
- Brochard Laurent
- Brodbeck Andreas
- Brohi Farooq
- Brooks Nicole
- Brown Cynthia
- Brown Julia
- Brown Louise
- Brown Nerissa
- Brown Zarah
- Brugman Curt
- Brunetta Enrico
- Brunkhorst Frank M.
- Brunskill Nigel
- Bryan-Morris Kayla
- Bryden Emma
- Budd Joanna
- Buehner Ulrike
- Buhay Megan
- Buhr Heidi
- Burbee Dylan
- Burda Dorota
- Burgess Richard
- Burke David
- Burke Tara
- Burkey Jason
- Burnish Rachel
- Burns Dean
- Burns Karen
- Burrell Aidan
- Burt Karen
- Buscher Hergen
- Butler Amelia
- Butler Magdalena
- Butler Susan
- Buxton Meredith
- Buzgau Adrian
- Byrne Kathleen
- Byrne Rahim
- Cabrelli Louise
- Cabreros Leilani
- Cairns Tom
- Calfee Carolyn
- Callahan Jean-Christophe
- Cambalova Lenka
- Campbell Andrew
- Campbell Bridget
- Campbell Debbie
- Campbell Hilary
- Campbell Lewis
- Campbell Marion
- Campbell Ryan
- Campion Alexandra
- Campisi Josie
- Camsooksai Julie
- Caplin Cecile
- Carbonneau Elaine
- Carmichael Samantha
- Carmona Rosario
- Carn Vanessa
- Carpio Lillian
- Carr Zoe
- Carr-Wilkinson Joanne
- Carrier François
- Carrier Marc
- Carter Angus
- Carter Brittney
- Carter David
- Carter Jay
- Carter Michael
- Casali Sherry
- Casey Ruth
- Casey Siobhan
- Castelain Vincent
- Castle James
- Cathcart Susanne
- Catorze Nuno José Teodoro Amaro dos Santos
- Cattelan Jessy
- Cavayas Alexandros
- Cawley Kathryn
- Cecconi Maurizio
- Centofanti John
- Chambers Emma
- Champanerkar Shreekant
- Chan Carmen
- Chan Charles
- Chan Peter
- Chapman Rachel
- Chapman Susan
- Charles Bethan
- Charles Walton
- Charlewood Richard
- Charlton Sam
- Charron Cyril
- Chartier Delphine
- Chasse Michael
- Chassé Michaël
- Chen Jonathan
- Chen Lixian
- Chen Yan
- Cheng Allen C.
- Cherian Shiney
- Chhablani Manish
- Chin Teri
- Chudeau Nicolas
- Chukkambotla Sri
- Ciccarelli Michele
- Cirstea Emanuel
- Clair Bernard
- Clark Amy
- Clark Michele
- Clark Richard
- Clark Sarah
- Clarke Frances
- Clarke Jennifer
- Claxton Andrew
- Cleary Joanne
- Clement Ian
- Clere-Jehl Raphael
- Clermont Giles
- Clermont Gilles
- Clinton Alison
- Cloutier Ève
- Cockrell Maeve
- Codreanu Daniel
- Coetzee Samantha
- Coghlan Phoebe
- Cole Jade
- Coles Jennifer
- Colin Gwenhael
- Collier Dawn
- Collins Amy
- Collins Daniel
- Collins Emma
- Collins Joanne
- Collins Érin
- Collis Matthew
- Combaux Daniele
- Commons Robert
- Comp Susan
- Concha Pablo
- Connolly Karen
- Constantini Elena
- Constantino-Occhipinti Claudia
- Contou Damien
- Convery Karen
- Conway Robert
- Conzelmann Nadine
- Cook Deborah
- Cook Tim
- Cooke Jill
- Cooke Justin
- Cooper Jamie
- Cooper Josh
- Cooper Lauren
- Cooper Melanie
- Cooper Nichola
- Corbett Sarah
- Corcoran Ele
- Corcoran Kathleen
- Cornell Sarah
- Cornell Thomas
- Cort Jon
- Costerousse Olivier
- Couillard-Chénard Émilie
- Courtin Laura
- Coutts Amanda
- Couture Lourie
- Cove Matthew
- Cowdrey Keri-Anne
- Cowley Nicholas
- Cowton Amanda
- Coyne Mark
- Craddock Richard
- Craner Michelle
- Craven Thomas
- Crawshaw Sarah
- Creagh-Brown Ben
- Creange Vanessa
- Cremer Olaf
- Crisp Nikki
- Croft Maria
- Csabi Peter
- Cudlipp Joanna
- Cuesta Jeronimo
- Cuffaro Raffaele
- Curley Gerard
- Currie Andrew
- Cusack Rebecca
- Cuthbertson Brian
- Cutler Sean
- Cárcel Sheila
- Côté Émilie
- D?Amato Fabiola
- D?Aragon Frédérick
- Daebis Admad
- Daher Rana
- Dale Katie
- Daley Jessica
- Dalton James
- Daly James
- Daly Zoe
- Daneman Nick
- Dark Paul
- Darnell Robert
- Darreau Cedric
- Daugherty Jason
- Davey Miriam
- Davidson Neil
- Davies Ellie
- Davies Gwyneth
- Davies Jennifer
- Davies Louisa
- Davies Michelle
- Davies Rhys
- Dawson Laura Ann
- Dawvda Ashlish
- Day Christopher
- Da Rocha Joana
- De Bus Liesbet
- de Courcy-Golder Kim
- de Groot Klaas
- de Jong Menno
- de Jonge Evert
- De Keulenaer Bart
- de la Torre Cisneros Julian
- de Man Angelique
- De Neef Mark
- De Smeytere Anouska
- Deacon Bethan
- Dean Steven
- Dean Tessa
- Dearden Joy
- Dechert William
- Declercq Pierre-Louis
- Degracia Anna
- del Sorbo Lorenzo
- Dela Rosa Arnold
- Delaney Kirsha
- Dell Abbie
- del Prado Michael
- Demetriou Carrie
- Dempster Debra
- Denham Lynn
- Denmade Craig
- Dent Martin
- Depante Maria
- Depuydt Pieter
- Dequin Pierre-François
- Derde Lennie P. G.
- Deshpande Kush
- Detry Michelle A.
- Deye Nicolas
- de la Fuente Carmen
- De Waele Jan
- Dheke Krishan
- Di Lucca Giuseppe
- Dias Priya
- Dice Julie
- Digby Stephen
- Diridis Kristina
- Distler Michael
- Dobell-Brown Kelsey
- Doble Patricia
- Dobson Jade
- Doherty Kaleigh
- Doherty Ronan
- Doi Yohei
- Dolman Rozzie
- Domingo-Marco Joana
- Donadee Chenell
- Donaldson Kate
- Dondrop Arjen
- Donegan Clare
- Donlon Sinead
- Donnelly Adrian
- Donnelly Kieran
- Donnison Phil
- Doonan Reece
- Doran Peter
- Dore Rachael
- Dormand Natalie
- Dos Santos Filipa
- Douillard Thomas
- Drake Chelsea
- Drapola Debra
- Drayss Maria
- Drummond Andrew
- Drury Kay
- Duan Erick
- Duberley Stephen
- Duffy Eamon
- Duffy Oscar
- Duke Graeme
- Duke Zoe
- Duncan Tracy
- Dunsavage Janice
- Duplaix Mathilde
- Duric Natalie
- Duroux Maree
- Dushianthan Ahilanandan
- Dyas Sarah
- Eapen Beena
- Eastgate Christine
- Ebenezer R
- Edmunds Natasha
- Edwards Alexandra
- Efford Georgia
- Egreteau Pierre
- Ehrmann Stephan
- Eichenauer Dennis
- Eisenbeis Simone
- Ekhérian Jean-Michel
- El-Khawas Khaled
- Elender Corinna
- Elgendy Ahmad
- Elhassan Munzir
- Ellervee Anneli
- Ellis Chiara
- Ellis Christine
- Ellis Yvette
- Elmahi Einas
- Elsefi Tarek
- Eltayeb Ayaa
- Elvira Evangeline
- England Jenna
- Englert Sarah
- English Shane
- Epelman¸ Slava
- Eroglu Ege
- Estcourt Lise J.
- Estensen Kristen
- Evans Amy
- Evans Andrew
- Evans Debra
- Evans Gabrielle
- Everitt Robert
- Evers Mirjam
- Evetts George
- Ewalds Esther
- Ezekowitz Justin
- Fagan Laura
- Fagbodun Elizabeth
- Farahi Neda
- Fareed Komal
- Farnell-Ward Sarah
- Fartoukh Muriel
- Faulkner Beverley
- Faulkner Maria
- Fazla Fathima
- Featherstone Peter
- Felton Tim
- Fennessy Gerard
- Ferguson Niall
- Ferguson Susan
- Fergusson Dean
- Fernandes Edna
- Fernandez Maria
- Fernando Gloria
- Fernández de Pinedo Artaraz Ziortza
- Ferreira Ricardo Manuel Castro
- Ferrier Janet
- Ferringer Cindy
- Fesz Jessica
- Fierens Jan
- Finch Cheryl
- Finn André
- Finn Stephanie
- Finnis Mackenzie
- Fiouni Sofia
- Fischer Roy
- Fitzgerald Mark
- Fitzpatrick Meghan
- Fletcher Simon
- Flint Neil
- Flor Thomas
- Florescu Simin
- Fluher Jure
- Flynn Gordon
- Focà Emanuele
- Folci Marco
- Forbes Andrew
- Ford Megan
- Forster Elliot
- Foster Tracy
- Fottrell-Gould Deirdre
- Foulds Angela
- Fowler Rob
- Fowler Robert
- Fox Claire
- Fox Eleonore
- Fragner Gertrud
- Frakking Thuy
- Franch-LLasat Diego
- Francis Olesya
- Francoeur François
- Francois Bruno
- Frankfurter Claudia
- Franz Christopher
- François Bourgerol
- Fraser Catherine
- Frater Alasdair
- French Craig
- Frey Anna
- Frey Christian
- Frise Matthew
- Frost Victoria
- Fuchs Ralph
- Fujitani Shigeki
- Fysh Ed
- Gachet Alexandre
- Galbiati Carola
- Galea James
- Ganesan Arunkumar
- Ganesan Manisha
- Ganguly Saibal
- Garcia Sara
- Gardiner-Hill Caroline
- Garot Denis
- Garrard Hywel
- Garrard William
- Garrett Peter
- Garrier Ludivine
- Garrod Esther
- Garton Mark
- Garvey James
- Gascoyne Rachel
- Gattas David
- Gauli Basanta
- Gay Alexandra
- Gaylard Jane
- Gellamucho Minerva
- Gemmell Lisa
- Gendall Emma
- Geng Wenli
- Geoghegan Pierce
- Geri Guillaume
- Geurts Heidi
- Ghaffari Mehrdad
- Ghamraoui Ali
- Ghattaoraya Amardeep
- Ghosh Alison
- Giardina Giuseppe
- Gibbins Alexandra
- Gill Mandy
- Gilliam Matthew
- Gilmour Kate
- Girard Timothy
- Girijadevi Dinuraj
- Gladas Kirsty
- Glasby Kathleen
- Gledhill Lisa
- Glister Georgina
- Glynou Loukia
- Goddard Wendy
- Godement Mathieu
- Godoy Lucas C.
- Goebeler M.E.
- Golden David
- Goldman John
- Goligher Ewan
- Gomez Keith
- Gommans Frank
- Goodwin Jayne
- Goossens Herman
- Gopal Shameer
- Gopinath Amitha
- Goralski Patricia
- Gordon Anthony C.
- Gosbell Iain
- Gould Richard
- Grady Bart
- Graham Cheryl
- Graham Libby
- Graniewski Jaroslaw
- Grant Caroline
- GrauNovellas Neus
- Greco Massimiliano
- Grecu Irina
- Green Cameron
- Green Jackie
- Greene Emma
- Greener Danni
- Gregory Jane
- Gresham Rebecca
- Greven Frances
- Grieve Richard
- Grimm Patrick
- Grimmer Lisa
- Groeneveld Erika
- Gross Jamie
- Grünewaldt Achim
- Guanco Mark
- Guerineau Elodie
- Guitton Christophe
- Gummadi Mahitha
- Gupta Abhinav
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- Kremling Julius
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- Krishnamoorthy S
- Krishnamurthy Vinodh
- Kruger Peter
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- Laver Russell D.
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- McArthur Colin J.
- McAuley Daniel F.
- McAuley Julie
- McCallion Edmund
- McCarthy Aine
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- McGoldrick Clare
- McGuigan Peter
- McGuinness Shay P.
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- Mouncey Paul R.
- Mowery Brent
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- Mtuwa Shelia
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- Oza Deepali
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- Panwar Rakshit
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- Paramasivam Elankumaran
- Parekh Dhruv
- Parikh Harshel G.
- Parke Rachael L.
- Parker Jane C.
- Parker Lorraine
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- Polgarova Petra
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- Ralston Maximillian
- Ramakrishnan N
- Ramali Mohamed
- Ramamurthi Balaji
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- Saull Michelle
- Saunders Christina T.
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- Shah Faraaz
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- Wright Kim
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- Wyatt Rachel
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- Xavier Kugan
- Yamagishi Yoshiaki
- Yamashita Chizuru
- Yang Yang
- Yarad Elizabeth
- Yates Bryan
- Yates David
- Yealy Donald
- Young Ian
- Young Meredith
- Young Paul
- Youngstein Taryn
- Yu Haili
- Yusuff Hakeem
- Zaharia Mihaela
- Zaidi Abbas
- Zaki Ahmed
- Zaman Mohsin
- Zarychanski Ryan
- Zdanavidiene Ausra
- Zhao Xiao
- Zinzoni Vanessa
- Zitter Letizia
- Zouita Louisa
- Publication venue
- 'American Medical Association (AMA)'
- Publication date
- 11/04/2023
- Field of study
IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19.
Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19.
DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022).
INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days.
MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes.
RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively).
CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes.
TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
- Author
- Abad-Motos Ane
- Abbas Ahmed M.
- Abbas Mostafa
- Abbasi Mujeeb
- Abbott Tom
- Abd Karim Muhammad Fairuz Shah
- Abdalaal Ibrahim
- Abdel-Galil Khalid
- Abdelemam Rania
- Abdelgawad Abdalrahman
- Abdelkarim Maryam
- Abdelkhalek Mohamed
- Abdelmageed Abdelfatah
- Abdelmawgoud Sherif
- Abdelmohsen Sarah
- Abdelrahman Ahmed Saber
- Abdelrahman Mostafa
- Abdelwahab Khaled
- Abdou Hossam
- Abdulai Darling Ramatu
- Abdulkhaleq Marwa
- Abdullah Bahiyah
- Abdulsalam Khalifa
- Abdulsalam Shuaib
- Abdur-Rahman Lukman
- Abdus-Salam Rukiyat
- Abdussalam Hameedat Opeyemi
- Abebrese John Tabiri
- Abeldaño Ariel
- Abou-Khalil Jad
- Abou-Taleb Hisham
- Abozid Anwaar
- Abozied Hesham
- Abrate Alberto
- Abu-Zaid Ahmed
- Abubakar Mohammed Kabir
- Abud Burçin
- Abuzaid Mohammed
- Adam Albushra Altayeb
- Adamina Michel
- Adamou Harissou
- Adamu Auwal
- Adamu Kabir Musa
- Adanu Kekeli
- Adebara Idowu
- Adebola Oluwaseyi
- Ademuyiwa Adesoji
- Adeniran Abiodun
- Adepiti Akinfolarin
- Aderogba Adeleke Akeem
- Adesunkanmi Abdulhafiz
- Adeyeye Ademola
- Adisa Adewale
- Adjeso Theophilus Justus Kofi
- Ads Adel Mohamed
- Ads Alaa Mohamed
- Adu-Aryee Nii Armah
- Adumah Collins
- Afzal Irrum
- Agapov Mikhail
- Agarwal Gaurav
- Agarwal Ravi
- Agbeko Anita Eseenam
- Agbeno Evans Kofi
- Agbonrofo Peter
- Agboola Oluseyi
- Aggarwal Gaurav
- Aghadi Ifeanyi
- Aghtarafi Natasha
- Agrawal Amit
- Agresta Ferdinando
- Aguado Héctor J.
- Aguilera-Arevalo Maria-Lorena
- Aherne Thomas
- Ahmad Aline
- Ahmad Maleeha
- Ahmad Misbahu
- Ahmad Sarwat
- Ahmad Shahzaib
- Ahmad Shoaib
- Ahmed Hayat Tarig Abdelhafiz
- Ahmed Khalid
- Ahmed Sharwany
- Ahmed Shima
- Ahmed Usama
- Aisuodionoe-Shadrach Oseremen
- Aitken Sarah
- Ajenifuja Kayode
- Ajiya Abdulrazak
- Akeel Nouf
- Akin Emrah
- Akinajo Opeyemi
- Akinyemi Tosin
- Akrida Ioanna
- Aktokmakyan Talar Vartanoglu
- Akwaisah Ayoub
- Al Bettar Osama
- Al-Badawi Ismail A.
- Al-Juaifari Maytham
- Al-Khyatt Waleed
- Al-Mallah Abdullah
- Al-Nusairi Ahmed
- Al-Saadi Nina
- Al-Sayaghi Khaled
- Al-Shaiji Tariq
- Al-Shehari Mohammed
- Al-Touny Aiman
- Al-Touny Shimaa A.
- Aladawi Omar
- Aladna Abdallah
- Alali Mahmoud
- Alam Mahmood
- Alam Mohammed Shadrul
- Alarabi Rehab
- Alawneh Yazan
- Alayande Barnabas
- Albanese Erminia
- Albayadi Eslam
- Albdour Maram
- Alconchel Felipe
- Alderazi Amer
- Alegbeleye Bamidele
- Alekberli Tural
- Alemu Misganaw Alemu Adimass
- Alexander Philip
- Alfieri Alex
- Algahtany Khaled
- Algarni Kamal
- Alhamad Ameen
- Alhamid Mohammad
- Alharmi Rawan A. Rahman
- Alharthi Mohammed
- Alhazmi Barrag
- Ali Mohamed Shafi Mahboob
- Ali Stephen
- Alibrahim Hidar
- Aljaaly Hattan
- Aljaiuossi Anas
- Aljanadi Firas
- Aljiffry Murad
- Aljirdabi Noof
- Alkahlan Mohammed
- Alkhalifa Elmustafa
- Alkhatib Sondos
- Alkhatieb Maram
- Allan Anna
- Almarshad Felwa
- Almgla Naser
- Almhimid Ali
- Almiqlash Bushray
- Almoshantaf Mohammad Badr
- Almutairi Abdulmjeed
- Alnsour Abed Alfattah Mahmoud
- Alobied Majd
- Alomar Osama
- Alonso Jesús Aarón Martínez
- Alonso Manuel Diez
- Alonso Nestor Fabian Pedraza
- Alonso Veronica
- Alqallaf Abdullah
- Alqaseer Asma
- Alrayes Bourhan
- Alsefri Maryam
- Alser Osaid
- Alsharif Mohammed
- Alsori Mohamed
- Altaf Abdulmalik
- Altinel Yuksel
- Altiner Saygin
- Altouny Ahmad
- Altun Demet
- Alvarez Natalia
- Alvarez-Lozada Luis Adrian
- Alvi Abdul
- Alwael Athari
- Alwash Mohammed
- Alyami Ziyad
- Alyousef Mohammed
- Alzahrani Saud
- Alzerwi Nasser
- Amin Shivang
- Amir Mohammed
- Ammar Ahmed Siddique
- Ammendola Michele
- Amores Remedios Revilla
- Amrayev Sultan
- Anastasiadou Sofia
- Ancans Guntis
- Anderson Caroline
- Andreani Lorenzo
- Andreotti Dario
- Andreuccetti Jacopo
- Andrianakis Alexandros
- Andro Christophe
- Anesi Alexandre
- Angamuthu Stephen
- Angeles Martina Aida
- Angelico Roberta
- Angelis Fragkiskos
- Angelou Dimitrios
- Angelou Kyveli
- Angulo Victor Pinto
- Anjum Arfa
- Anjum Muhammad Ayyub
- Annicchiarico Alfredo
- Anoldo Pietro
- Ansaloni Luca
- Anthoulakis Christos
- Antonelli Amedeo
- Anwar Mohamed
- Anwar Sumadi Lukman
- Anwer Mariyah
- Anyanwu Lofty-John
- Apostolou Christos
- Apostolou Konstantinos
- Appiah-Kubi Adu
- Aprea Giovanni
- Arbab Hana
- Archer James
- Ardura Francisco
- Aremu Muyiwa
- Arif Tahera
- Arkani Samara
- Armatura Giulia
- Armijos Daniel
- Arnaout Ali
- Arnaoutoglou Eleni
- Arnaud Alexis P.
- Arneja Jugpal
- Arrangoiz Rodrigo
- Arshad Muhammad
- Arthur Joshua
- Ashcroft James
- Ashford Bruce
- Ashraf Fariha
- Asiimwe Daniel
- Asirifi Samuel Amoako
- Asla Amir
- Aslam Ramisha
- Aspide Raffaele
- Ataya Karim
- Ateca Ibabe Villalabeitia
- Atici Semra Demirli
- Atis Gokhan
- Atkins William
- Atkinson Kate
- Attwood Joseph
- Auerkari Aino
- Augestad Knut Magne
- Augustin Goran
- Aujayeb Avinash
- Avella Pasquale
- Awad Ahmed K.
- Awad Hadeel
- Awad Rabih
- Awad Selmy
- Ayad Kusay
- Ayana Birhanu
- Aydin Yener
- Ayeni Funbi
- Aytac Erman
- Azab Ahmed
- Azami Rizwan
- Azize Diallo Abdoul
- Azzam Ahmed Y.
- Azzis Olivier
- Baba Yabasin Iddrisu
- Babis George
- Bacalbasa Nicolae
- Badiani Sarit
- Badran Saif
- Baduell Albert
- Baeesa Saleh
- Baertschiger Reto
- Bafaquh Mohammed
- Bahassan Omar Mohammed
- Bahrami-Hessari Michael
- Baia Marco
- Baidoo Ebikela Ivie
- Bailey Karen
- Baili Efstratia
- Bains Lovenish
- Baiocchi Gian Luca
- Baiocchi Glauco
- Baiyewu Lateef Ayodele
- Bajaj Ankur
- Bajunaid Khalid
- Balagobi Balasingam
- Balasubramanian Ishwarya
- Balduzzi Alberto
- Baldwin Alexander
- Balla Andrea
- Balogh Zsolt J.
- Balogun James A.
- Balogun Simon
- Baloyiannis Ioannis
- Ban Vin Shen
- Bandyopadhyay Samik Kumar
- Bandyopadhyay Soham
- Banerjee Sumit
- Banipal Gurpreet Singh
- Banky Balazs
- Bannone Elisa
- Bansal Sujesh
- Barberis Andrea
- Barbosa-Breda Joao
- Bareka Metaxia
- Barišić Tatjana
- Barlas Aziz Mutlu
- Barlow Ciaran
- Barmayehvar Behrad
- Baroffio Paolo
- Barone Mirko
- Barra Fabio
- Barranquero Alberto G.
- Barugola Giuliano
- Basendowah Mohammed
- Bashir Mahmod
- Basnayake Oshan
- Bass Gary Alan
- Basu Somprakas
- Bateman Antony
- Bateman Kellie
- Batista Sylvia
- Batstone Martin
- Bauer Marlies
- Bauset Juan Carlos Catalá
- Bawa Ashvind
- Bawa Sayesha
- Bayhan Hüseyin
- Bayo Heura Llaquet
- Bazzi Nagham
- Beamish Andrew
- Beasley Nigel
- Beatty Jasmine Winter
- Becerra Angel
- Bedada Alemayehu Ginbo
- Bedzhanyan Arkady
- Begum Farzana
- Beisenov Bekzat
- Bellio Gabriele
- Bello Usman Mohammed
- Bellés Ana Ciscar
- Belzile Etienne
- Benamar Safia
- Bence Matthew
- Benshetrit Guy
- Bensoltane Khadidja
- Bergkvist David Julià
- Beristain-Hernandez Jose-Luis
- Bernante Paolo
- Bernardi Daniele
- Beron Reinaldo Isaacs
- Berselli Bruno
- Berselli Mattia
- Bertelli Giacomo
- Bertoglio Pietro
- Bertolaccini Luca
- Beswick Daniel
- Bette Birgit
- Bezirci Rifat
- Bhangu Aneel
- Bharathan Rasiah
- Bhat Vivek
- Bhatti Khalid
- Bianchi Valentina
- Bianco Francesco
- Bianco Giuseppe
- Bijou Walid
- Bilfaqirah Majed
- Biloslavo Alan
- Bin Alhassan Baba Alhaji
- Binnawara Muhannud
- Bissacco Daniele
- BİŞGİN TAYFUN
- Blair James
- Blanco Jose
- Blencowe Natalie
- Bloemers Frank
- Board Timothy
- Bobak Peter
- Boccalatte Luis
- Boedo Maria Jesus Maroño
- Bohmer Rob
- Boira Mar Achalandabaso
- Boisson Matthieu
- Boligo Sofia
- Bolton William
- Bombardini Cristina
- Bonavina Luigi
- Bonci Eduard-Alexandru
- Bondurri Andrea
- Bonilla Antonio Ramos
- Bonsaana Gilbert Batieka
- Booth L.
- Borg Elaine
- Borges Miguel Fróis
- Borges Nuno
- Bork Ulrich
- Borselle Dominika
- Bortul Marina
- Botelho Pedro
- Bottari Andrea
- Bouchagier Konstantinos
- Bouliaris Konstantinos
- Bowan Antoinette Bediako
- Bowen Joel
- Bozbiyik Osman
- Bracale Umberto
- Brachini Gioia
- Bramis Konstantinos
- Branagan Graham
- Branzan Daniela
- Brasset Camille
- Bratus Dejan
- Bravo Ana Maria Minaya
- Bravo Sybil Lizanne
- Bright Tim
- Brisinda Giuseppe
- Brodkin Edgar
- Broglia Alessandro
- Brolese Alberto
- Browning Rebecca
- Bruzzaniti Placido
- Brzeszczyński Filip
- Bsisu Isam
- Bua Emmanuel
- Budd Gabrielle
- Bukhari Syed Imran
- Bulian Dirk Rolf
- Bumbasirevic Uros
- Bumber Boris
- Burgos-Blasco Barbara
- Burlov Nikita
- Bussu Francesco
- Bàmbina Fabrizio
- Börner Nikolaus
- Böttcher Arne
- Cabeza Leticia
- Cabrera Marino
- Cais Simon
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- Capobianco Mattia
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- Capozzi Enrico
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- Carretero Manuel Moriche
- Caruana Edward J.
- Carvello Michele
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- Castaño Mario
- Castaño-Leon Ana M.
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- Christodoulou Prokopis
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- Cross George W. V.
- Cruz Ricardo Pedrini
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- Cunningham Brian
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- D'Acapito Fabrizio
- D'Addino José Luis
- D'Amico Alessia
- D'Amore Anna
- D'Andrea Giancarlo
- D'Archi Sabatino
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- Dawson Jonathon
- Dbouk Samer
- De Alarcón Jaime Rodríguez
- De Andrés-Asenjo Beatriz
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- Katsura Morihiro
- Kauppila Joonas H
- Kaur Amanjot
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- Kent Alistair J
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- Labib Peter
- Laborde Mario Mella
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- Lazarou Lazaros
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- Leventoǧlu Sezai
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- Liang Rhea
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- Lichman Leonid
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- Lim Yizhe
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- Lin Shuxun
- Lindegger Daniel
- Linero Inmaculada Benítez
- Ling Samuel
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- Locatello Luca Giovanni
- Lohmann Tibor Karl
- Lohse Helmut Alfredo Segovia
- Lohsiriwat Varut
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- Lopez Paloma Rodriguez
- Losada Manuel
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- Loubani Mahmoud
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- Lucchini Stefano
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- Lyra Humberto Fenner
- Mabood Waleed
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- MacHain V Gustavo Miguel
- MacHairas Nikolaos
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- Maestri Marco
- Maffioli Anna
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- Magalhães Carlos
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- Magnone Stefano
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- Maguire Patrick J.
- Mahečić Tina Tomić
- Mahmood Fahad
- Mahmoud Abdelrahman
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- Malek Bouhani
- Malik Aamer
- Malik Awais Amjad
- Malik Muhammad Isfandyar Khan
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- Mallick Rebecca
- Mallmann Christoph
- Mallmann Michael R.
- Mambrilla Sara
- Manangi Mallikarjuna
- Manesh Hassan Fatemi
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- Manigrasso Michele
- Manjula S.
- Mannan Syed
- Mantziari Styliani
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- Martinelli Fabio
- Martinez-Leo Bruno
- Martinez-Mier Gustavo
- Martinez-Perez Carolina
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- Martins Ana
- Martins Claudia Pinto
- Martins Paulo N.
- Martínez Daniel Fernández
- Martínez Eunate Ganuza
- Martínez Verónica Martín
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- Masri Ruqaya
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- Massoud John
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- Matthews Emily
- Mauriello Claudio
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- Mayer Horacio F.
- Mayo-Yáñez Miguel
- Mazzarella Gennaro
- Mbodi Langanani
- Mbwele Bernard
- McAleer Stephen
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- McGrath John
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- McLean Aaron Lawson
- McLeish Bethan
- McPherson Duncan
- Meara John G.
- Meead Adullah
- Mehraj Asif
- Meilak Joseph
- Meleiro Hugo
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- Mendiola Gian
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- Meneghini Simona
- Mengesha Mengistu G.
- Menna Maria Paola
- Menon Arun
- Meola Antonio
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- Migliore Marcello
- Migliorelli Federico
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- Moda Nupur
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- Mohamed Guleed
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- Mohamedahmed Ali Yasen Y.
- Mohammed Alhassan Datti
- Mohammed Alsnosy Abdullah Khalefa
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- Mohan Helen
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- Mok Chi Wei
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- Morelli Luca
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- Morezzi Daniele
- Morgan Eghosa
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- Moro Ana María Gimeno
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- Mostafa Badr
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- Mustafa Hamid
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- Mutlu Özgecan Piril Zanbak
- Mutter Didier
- Mvukiyehe Jean Paul
- Mwenda Aruyaru Stanley
- Myrelid Par
- Myriokefalitaki Eva
- Méndez Patricia Serrano
- Nabil Fatma
- Nachelleh Emmanuel Aadereyir
- Nacion Aeris Jane D.
- Nadi Khaldoun
- Naegele Felix
- Naga Hani
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- Nahm Christopher
- Naimzada Mukhammad David
- Nakano Luis
- Nanjiani Deedar
- Nankivell Paul
- Naranjo Eddy P. Lincango
- Narayanan Vairavan
- Nardo Bruno
- Narvaez-Rojas Alexis Rafael
- Nassar Mahmoud A.
- Nasser Sara
- Nastos Constantinos
- Natale Joseph
- Nataraja Ramesh
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- Naumann David
- Navarrete-Peón Alberto
- Navarro-Barrios Alvaro
- Nazer Ahmed
- Nazimi Abd Jabar
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- Negoi Ionut
- Negussie Abraham
- Nemeth Marcus
- Nenna Antonio
- Nepogodiev Dmitri
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- Nevins Edward J.
- Newman Samuel
- Ngaserin Sabrina
- Nicholson Gary
- Niewiera Marc
- Nigh Joe
- Nikolouzakis Taxiarchis
- Nikolovska Bisera
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- Nissi Evelyn R.
- Nitschke Christine
- Njokanma Iloba
- Noel Colin
- Nolte Peter
- Noureldin Yasser
- Novello Simone
- Novysedlák René
- Ntalouka Maria P.
- Ntirenganya Faustin
- Nugur Ashwani
- Nuhu Ahmed Mohammed
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- O'Connell Robert Michael
- O'Connor Alexander
- O'Dwyer Marliza
- O'Riordan James
- Odai Emeka Danielson
- Odicino Franco
- Ofori Emmanuel Owusu
- Ogu Rosemary
- Ogundoyin Olakayode
- Ogundoyin Oluwole
- Oh Ke En
- Ohazurike Ephraim
- Ojewuyi Olufemi
- Ojo Owolabi
- Okere Oghenekevwe
- Okereke Chukwuma
- Okhakhu Amina
- Okpani Charles
- Oktseloglou Vlasios
- Okunade Kehinde
- Oladimeji Abraham
- Olaogun Julius
- Oliver Isabel Mora
- Olivos Maricarmen
- Olori Samson
- Olson Kristofor A.
- Oludara Mobolaji
- Omar David
- Omar Islam
- Omer Mohammed Eltahier Abdalla
- Ong Chon Sum
- Onyeagwara Ngozi
- Onyemaechi Ndubuisi
- Ooi Rucira
- Orecchia Luca
- Ornaghi Sara
- Orsoo Soyombo
- Ortega Eduardo Nieto
- Osborn Tamara
- Oshodi Yusuf
- Osman Hany
- Osman Osama Saeed
- Osterhoff Georg
- Othman Ahmad Faidzal
- Othman Amani Alsayd Abdulsalam
- Othman Rema
- Otify Esraa
- Otokwala Job
- Oung Thida
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- Shoukrie Shoukrie I. M.
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- Siboe Mark
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- Sodhai Vivek
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- Sole-Sedeno Josep M.
- Soljic Martina
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- Soon Wai Cheong
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- Sotudeh Mohadeseh
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- Spiers Harry V. M.
- Spina Alfio
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- Stevenson Andrew
- Stewart Grant D.
- Stijns Jasper
- Stogowski Piotr Tomasz
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- Strotmann Johanna Josefine
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- Su Yu-Xiong
- Suarez Sara Busto
- Subramani Yamini
- Subramaniam Sentilnathan
- Sue-Chue-Lam Colin
- Suer Muhammed Salih
- Sulaiman Bilal
- Sultania Mahesh
- Sundarraju Shalini
- Sungurtekin Hulya
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- Vázquez Gil
- Vázquez Irene Ortega
- Vǎcǎraşu Andrei Bogdan
- Wade Ryckie
- Wafi Omar
- Wagner Gabriela
- Wallis Christopher
- Wanjara Samuel
- Waqar Shahzad Hussain
- Warden Claire
- Warner Christian
- Wasim D.
- Wason Shaun
- Wasserman Isaac
- Watcyn-Jones Tom
- Waterson Ben
- Watson David
- Watson Matthew
- Weber Clemens
- Wheatstone P.
- Wheeler James
- Wheldon Luke
- White Michelle
- White Stuart
- White William
- Wickramasinghe Dakshitha
- Widmer Lukas Werner
- Wiedemann Dominik
- Wiesinger Clemens Georg
- Wijekoon Naveen
- Wijenayake Wasantha
- Wijeyaratne Manuk
- Wijeysundera Duminda
- Wiles Matthew
- Wilkin Richard
- Wilkins Alex
- Wilkins James
- William Tinka George
- Williams Omolara Modupe
- Williams Shekinah
- Windsor John
- Winnand Philipp
- Wittmann Maria
- Wolde Amanuel
- Wolfenden John W. D.
- Wong Benjamin Ngie Xiong
- Wong Enoch
- Wong Evan G.
- Wong George Kwok Chu
- Wong Ho Ying Flora
- Wong Kai Yuen
- Wormald Justin
- Wright Deborah
- Wright Joshua
- Wu Fiona
- Wurm Markus
- Xenaki Sofia
- Yadev Ip
- Yahaya Ahmad Shuib
- Yakubu Mustapha
- Yang Wah
- Yanik Özge
- Yanowsky-Reyes Guillermo
- Yassin Abubaker
- Yates Elizabeth
- Yebes Alvaro
- Yenli Edwin Mwintiereh Ta-Ang
- Yeoh Tien
- Yeung Justin
- Yiallourou Anneza
- Yigit Banu
- Yildirim Asif
- Yim Guang
- Yiu Andrew
- Yonekura Hiroshi
- Yotsov Tsanko
- Younis Muhammad Umar
- Yunus Alif
- Yusefi Hossein
- Zabaleta Jon
- Zabkiewicz Catheriner
- Zaccaria Giulia
- Zacharia Bincy
- Zafar Syed Nabeel
- Zago Mauro
- Zaheen Zakia
- Zahid Zahra
- Zaimis Tilemachos
- Zakaria Andee Dzulkarnaen
- Zambon Martina
- Zamora Lindsey
- Zampogna Biagio
- Zancana Giuseppa
- Zani Augusto
- Zanin Luca
- Zanini Nicola
- Zapardiel Ignacio
- Zapata Carlos Shiraishi
- Zarif Pierre
- Zaránd Attila
- Zehnder Philipp
- Zenger Serkan
- Zenha Horácio
- Zhu Michael Z. L.
- Ziemann Sebastian
- Zimak Danijela Mrazovac
- Zimak Zoran
- Zivkovic Dragana
- Zizzo Maurizio
- Zucker Benjamin
- Zwain Yasir
- Zyskowski Michael
- Ávila Clara Castro
- Älgå Andreas
- Çakici Mehmet Çaǧlar
- Çelik Enes
- Çelik Meryem Nur
- Özçay Necdet
- Şevik Hüsnü
- Šantak Goran
- Šimko Kristián
- Žatecký Jan
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2023
- Field of study
Abstract
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries
DEVELOPMENT OF AGRICULTURAL EDUCATION IN AGRO INNOVATION PARK
- Publication venue
- 'Universitas Pancasila'
- Publication date
- 22/12/2022
- Field of study
Tourism activities are not only to spend free time and vacation to relieve fatigue, but also increase knowledge and gain educational insight outside public schools. Efforts to meet these interests then formed a recreation area in which there is an element of edutourism. Edutourism is a mixture of tourism and educational activities. One of the places that provides educational tours is the Agro Innovation Park or commonly called Tagrinov. Tagrinov must revive sensations and experiences that can generate interest in revisiting tourists after being satisfied by previous visits, because the experience felt by tourists is one of the considerations for visitors when choosing tourism activities, therefore the measurement of experience can be measured by Experiential Marketing which includes components Sense, Feel, Think, Act, RelateKegiatan pariwisata bukan hanya untuk menghabiskan waktu luang dan berlibur menghilangkan penat, namun juga menambah pengetahuan serta mendapat wawasan pendidikan di luar sekolah umum. Upaya untuk memenuhi minat tersebut maka dibentuklah tempat rekreasi yang didalamnya terdapat unsur eduwisata. Eduwisata ialah campuran antara kegiatan wisata dan pendidikan. Salah satu tempat yang menyediakan wisata edukasi ialah Taman Agro Inovasi atau biasa disebut Tagrinov. Tagrinov harus membangkitkan kembali sensasi serta pengalaman yang dapat memunculkan minat berkunjung ulang wisatawan setelah merasa puas oleh kunjungan sebelumnya, karena pengalaman yang dirasakan oleh wisatawan menjadi salah satu pertimbangan pengunjung saat memilih kegiatan wisata maka dari itu pengukuran pengalaman dapat diukur dengan Experiental Marketing yang didalamnya terdapat komponen Sense, Feel, Think, Act, Relate
Prophylactic biological mesh reinforcement versus standard closure of stoma site (ROCSS): a multicentre, randomised controlled trial
- Author
- Abbott Sian
- Acheson Austin
- Addison Sarah
- Adedeji Olufunso
- Adeosun Abidemi
- Agarwal Anil K.
- Aghahoseini Assad
- Ahmed Ishmail
- Akbar Ayesha
- Al Araimi Aamed
- Al-Rashedy Mohammed
- Alalawi Rashid
- Alexander David J.
- Ali Wadah
- Allison Andrew
- Allison Joanna
- Allsop Lynne
- Amarnath Talakalukoppa
- Amey Isobel
- Antoniou Anthony
- Archer James
- Ardley Rohan
- Aryal Kamal
- Ashdown-Phillips Steve
- Ashraf Shazad
- Atkari Bence
- Atkinson Angela
- Bach Simon
- Badrinath Krishnamurthy
- Baird Yolanda
- Bamford Richard
- Bandyopadhyay Dibyendu
- Banerjee Amlan
- Baragwanath Phil
- Beggs Andrew
- Bemelman Willem
- Beral Dan
- Bhangu Aneel
- Bignell Mark
- Bisgaard Thue
- Blodwell Michelle
- Blussé Marjolein
- Borowski David
- Borstlap Wernard
- Bradford Ian
- Bradley-Potts Joanne
- Branagan Graham
- Broadley Graham
- Broardhurst Jack
- Brown James
- Budhoo Misra Rai
- Bullen Timothy
- Bunni John
- Burgess Amanda
- Busch Olivier R. C.
- Buskens Christianne
- Butcher Katrina
- Butt Mansoor
- Cagigas Carmen
- Canny John
- Chambers Joanne
- Chandler Dawne
- Chang Jessica
- Charleston Peter
- Chaudhri Sanjay
- Chave Helen
- Chitsabesan Praminthra
- Church Robert
- Clark Sue
- Clouston Hamish
- Coleman Zoe
- Colley Julie
- Cooke Jill
- Cosier Tracey
- Cotton David
- Courtney Edward
- Cripps Heather
- Cripps Neil
- Cruickshank Neil
- Cruttenden-Wood David
- Cunha Melissa
- Curtis Nathan
- D'Costa Conrad
- D'Souza Nigel
- Daliya Prita
- Dalton Richard
- Dalton Stephen
- Das Parthasarathi
- Datt Pooja
- Dattani Mit
- Dawson Robin
- Dawson Sarah
- de Nes Lindsey
- Dean Hilary
- Dennison Godwin
- Dimitriou Nikolletta
- Docherty James G.
- Dube Mukul
- Duff Sarah
- Dunn Yvonne
- el-Sayed Charlotte
- el-Sharkawy Ahmed
- Elgaddal Sanaa
- Essapen Sharadah
- Fairey Howard
- Fallis Simon
- Farmer Martin
- Fatayer Taher
- Fensom Catherine
- Flindall Ian
- Forde Colm
- Foster Gemma
- Foster Jake
- Francis Nader
- Frost Victoria
- Furtado Sanjay
- Futaba Kaori
- Garg Dharmendra
- Garimella Veerabhadram
- Gates Zoe
- Gaunt Anne
- Ghanem Yasser
- Ghods-Ghorbani Manijeh
- Gibbins Jackie
- Gibbons James
- Gibson Andrew
- Gill Kathryn
- Gill Michael
- Gill Talvinder
- Gilmore Lydia
- Gipson Anna
- Glasbey James
- Glennon Ana
- Glister Georgina
- Goh Jason
- Gok Muhammed
- Goldsmith Paul
- Gourevitch David
- Gray Catherine
- Green Marie
- Green Nikki
- Greenslade Susanna
- Gupta Robin
- Hall Emily
- Halls Mark
- Hamdan Mohammed
- Hammond Toby
- Handley Kelly
- Hardstaff Lisa
- Hardwick Anne
- Hargest Rachel
- Harris Guy
- Hawash Ahmed
- Haydon Geoffrey
- Hayes Anne
- Heeley Cheryl
- Heywood Nick
- Hilken Nicholas
- Hill Dennise
- Hill Matt
- Hind Richard
- Hodgkins Kathryn
- Hogben Karen
- Holford Erika
- Hollyman Marianne
- Houlihan Rebecca
- Hunter Mark
- Hussain Anwar
- Iglesias Vecchio Miriam
- Ismail Tariq
- Ives Natalie
- Jackson Richard
- Javaid Ali
- Jenkins Ian
- Johnston Tracey
- Jones Stephanie
- Jowett Susan
- Joy Howard
- Junejo Muneer
- Kamabjha Carrington
- Kapur Sandeep
- Karandikar Sharad
- Katebe Joyce
- Keh Christopher
- Kelsey Susan
- Kennedy James
- Kennedy Robin
- Khan Sarah
- Khatri Chetan
- Klaver Charlotte
- Kocialkowski Cezary
- Kshatriya Kirosh Shankar
- Kynaston James
- Lal Roshan
- Lalor Helen
- Lamparelli Michael J.
- Lancaster Nicola
- Lasithiotakis Kostas
- Leek Susan
- Lenehan Fionnaula
- Levy Bruce
- Lewis Alison
- Lewis Mark
- Lilly Helen
- Lim Michael
- Loganathan Sadasivam
- Longman Rob
- Lowe Amelia
- Mackenzie Felicity
- Macleod Kathleen
- Maeda Yasuko
- Magill Laura
- Malik Kamran
- Mangam Sudhakar
- Manning Chris
- Marsman Hendrik
- Mason David
- McCormick Richard
- McCullough Peter
- Mckenzie Paul
- McNichol Lisa
- Mehta Samir
- Messenger David
- Mirza Mehboob
- Mirza Nazzia
- Misselbrook Alison
- Mohamad Ashiq
- Mohamed Zakir
- Monaghan Eimar
- Moore Sally
- Moreton Sarah
- Morton Dion
- Morton Dion G.
- Muhammad Karim
- Munetsi Lorraine
- Munipalle Phanibhushana Chakravarthy
- Narewal Mandip
- Narula Harjeet
- Nash Dominic
- Nastro Piero
- Nath Rabindra
- Navid Ahmad
- Nepogodiev Dmitri
- Netherton Kimberley
- Ng Oliver
- Ng Paul
- Nicol Deborah
- Nisar Pasha
- Norwood Michael
- Obreja Mugurel
- Obukofe Ross
- Ockrim Jonathan
- Odogwu Steve
- Oglesby Arabis
- Ogunbiyi Olagunju
- Orbell James
- Owais Anwar
- Owen Harriet
- Paily Abhilash
- Pal Atanu
- Palfreman Andrea
- Pallan Arvind
- Panagiotou Dimitrios
- Papettas Trifonas
- Paraoan Marius
- Parmar Kathryn
- Patel Abhilasha
- Patience Lesley
- Peacock Oliver
- Phillips Robin K. S.
- Phillpott Catherine
- Pinkney Thomas
- Pinkney Tom
- Plowright James
- Poh Aaron
- Polyzois Konstantinos
- Preston Stephen
- Qureshi Nafees
- Rabie Mohamed
- Radley Simon
- Rajesh Arumugam
- Ramesh Aswatha
- Rankin Jayne
- Ranstorne Edward
- Rao Milind
- Ravikumar Rathinam
- Rawstorne Edward
- Rea Mr
- Reddan Julie
- Reddy Bala
- Richardson Jonathan
- Richardson Lisa
- Ridgway Stephanie
- Roberts Tracy
- Rosbergen Melissa
- Rosenstock Steffen
- Roy Pratik
- Royle Timothy J.
- Sadat Mohammed
- Sargen Kevin
- Sawant Amruta
- Scott Humphrey
- Sewell Terri-Ann
- Shabbir Jamshed
- Shah Tahir
- Sharma Abhiram
- Sharma Parveen
- Sharma Rishabha
- Siddiqui Kamran
- Sidebotham Jane
- Simms John M.
- Singh Baljit
- Singh Jagdeep
- Skull Angela
- Slater Andrew
- Sleight Simon
- Smart Chris
- Smolen Susan
- Solkar Mamoon
- Speakman Christopher
- Spurdle Katie
- Stojkovic Stevan
- Strandfelt Pernille
- Stringer Joanna
- Stroud Robert
- Stubbs Benjamin
- Subramanian Krishnan
- Suggett Nigel
- Sutaria Rupesh
- Swan Elaine
- Tabaqchali Mohamed
- Talwar Anjay
- Tanis Pieter
- Tate Jeremy
- Taylor Tracey
- Tayyab Muhammad
- Telford Karen
- Tennakoon Athula
- Thomas Ian
- Thomasset Sarah
- Thompson Chris
- Thrush Jessica
- Thumbe Vijay
- Tilley Alison
- Toms Julie
- Topliffe Joanne
- Torrance Andrew
- Townley Barbara
- Trickett Jonathan
- Trivedi Prateesh
- van Ruler Oddeke
- Varadharajan Saseendran
- Varghese Philip
- Velchuru Vamsi
- Vere Joanne
- Vijayan Deepak
- Vince Alexandra
- Vincent Tracy
- Vohra Ravinder
- Wagstaff Lynda
- Wairaich Naseem
- Waite Kathryn
- Walker Kenneth G.
- Walker Michael
- Walters Michael
- Ward Kym
- Ward Stephen
- Warusavitarne Janindra
- Watson Angus J. M.
- Watson Nicholas
- Westen Mikkel
- Westerduin Emma
- White Daniel
- White Tim
- Wicherts Dennis
- Wilhelmsen Elva
- Wilkin Richard
- Wilkings Lisa
- Wilkinson Lesley
- Williams Claire
- Williams Graham
- Williams Nigel
- Williamson Michael E. R.
- Wilsher Simon
- Wilson Deborah
- Wilson Tim
- Wong Ling S.
- Wood James
- Woodcock Nicholas
- Wordie Alexander
- Wright Monica
- Yeomans Neil
- Yeung Denise
- Youssef Haney
- Yu Ly-Mee
- Zulueta Elzbieta
- Publication venue
- 'Elsevier BV'
- Publication date
- 08/02/2020
- Field of study
Background: Closure of an abdominal stoma, a common elective operation, is associated with frequent complications; one of the commonest and impactful is incisional hernia formation. We aimed to investigate whether biological mesh (collagen tissue matrix) can safely reduce the incidence of incisional hernias at the stoma closure site. Methods: In this randomised controlled trial (ROCSS) done in 37 hospitals across three European countries (35 UK, one Denmark, one Netherlands), patients aged 18 years or older undergoing elective ileostomy or colostomy closure were randomly assigned using a computer-based algorithm in a 1:1 ratio to either biological mesh reinforcement or closure with sutures alone (control). Training in the novel technique was standardised across hospitals. Patients and outcome assessors were masked to treatment allocation. The primary outcome measure was occurrence of clinically detectable hernia 2 years after randomisation (intention to treat). A sample size of 790 patients was required to identify a 40% reduction (25% to 15%), with 90% power (15% drop-out rate). This study is registered with ClinicalTrials.gov, NCT02238964. Findings: Between Nov 28, 2012, and Nov 11, 2015, of 1286 screened patients, 790 were randomly assigned. 394 (50%) patients were randomly assigned to mesh closure and 396 (50%) to standard closure. In the mesh group, 373 (95%) of 394 patients successfully received mesh and in the control group, three patients received mesh. The clinically detectable hernia rate, the primary outcome, at 2 years was 12% (39 of 323) in the mesh group and 20% (64 of 327) in the control group (adjusted relative risk [RR] 0·62, 95% CI 0·43–0·90; p=0·012). In 455 patients for whom 1 year postoperative CT scans were available, there was a lower radiologically defined hernia rate in mesh versus control groups (20 [9%] of 229 vs 47 [21%] of 226, adjusted RR 0·42, 95% CI 0·26–0·69; p<0·001). There was also a reduction in symptomatic hernia (16%, 52 of 329 vs 19%, 64 of 331; adjusted relative risk 0·83, 0·60–1·16; p=0·29) and surgical reintervention (12%, 42 of 344 vs 16%, 54 of 346: adjusted relative risk 0·78, 0·54–1·13; p=0·19) at 2 years, but this result did not reach statistical significance. No significant differences were seen in wound infection rate, seroma rate, quality of life, pain scores, or serious adverse events. Interpretation: Reinforcement of the abdominal wall with a biological mesh at the time of stoma closure reduced clinically detectable incisional hernia within 24 months of surgery and with an acceptable safety profile. The results of this study support the use of biological mesh in stoma closure site reinforcement to reduce the early formation of incisional hernias. Funding: National Institute for Health Research Research for Patient Benefit and Allergan
The Global Retinoblastoma Outcome Study: a prospective, cluster-based analysis of 4064 patients from 149 countries
- Author
- Abdallah Elhassan
- Abdullahi Shehu U.
- Abdulqader Rula A.
- Abdulrahaman Aminatu A.
- Abouelnaga Sherif
- Ademola-Popoola Dupe S.
- Adio Adedayo
- Afifi Mahmoud A.
- Afshar Armin R.
- Aggarwal Priyanka
- Aghaji Ada E.
- Ahmad Alia
- Akib Indonesia Marliyanti N. R.
- Akinsete Adeseye
- Al Ani Mouroge H.
- Al Harby Lamis
- Al Mesfer Saleh
- Al-Badri Safaa A. F.
- Al-Dahmash Saad A.
- Al-Haddad Christiane E.
- Al-Hussaini Hamoud Hy
- Al-Jadiry Mazin F.
- Al-Janabi Allawi N. Hussein
- Al-Jumaily Usama
- Al-Mafrachi Ali A. R. M.
- Al-Shaheen Athar A. S. M.
- Al-Shammary Entissar H.
- Alarcon Portabella Silvia
- Alcasabas Ana Patricia A.
- Alejos Amanda
- Alemany-Rubio Ernesto
- Ali Amany M.
- Alia Donjeta B.
- Alkatan Hind M.
- All-Eriksson Charlotta
- Almeida Argentino A.
- Alsawidi Khalifa M.
- Amani Theophile B. Kabesha
- Amankwaa-Frempong Doreen
- Amiruddin Primawita O.
- Armytasari Inggar
- Astbury Nicholas J.
- Atalay Hatice T.
- Ataseven Eda
- Atchaneeyasakul La-ongsri
- Atsiaya Rose
- Autrata Rudolf
- Balaguer Julia
- Balayeva Ruhengiz
- Barranco Honorio
- Bartoszek Paulina
- Bartuma Katarina
- Bascaran Covadonga
- Bechrakis Nikolaos E.
- Begimkulova Ainura S.
- Benmiloud Sarra
- Berete Rokia C.
- Berry Jesse L.
- Bhaduri Anirban
- Bhat Sunil
- Bhattacharyya Arpita
- Biewald Eva M.
- Binkley Elaine
- Bio Amadou I. Alfa
- Blum Sharon
- Bobrova Nadia
- Boldt H. C.
- Bonanomi Maria Teresa B. C.
- Bouda Gabrielle C.
- Bouguila Hedi
- Bowman Richard
- Brennan Rachel C.
- Brichard Benedicte G.
- Buaboonnam Jassada
- Budiongo Aleine
- Burton Matthew J.
- Calderon-Sotelo Patricia
- Calle Jara Doris A.
- Camuglia Jayne E.
- Cano Miriam R.
- Capra Michael
- Carreras Yvania Alfonso
- Caspi Shani
- Cassoux Nathalie
- Castela Guilherme
- Castillo Luis
- Catala-Mora Jaume
- Cavieres Isabel
- Chandramohan Arthika
- Chantada Guillermo L.
- Chaudhry Shabana
- Chawla Bhavna
- Cheikh Sidi Sidi
- Chen Wensi
- Chiwanga Faraja S.
- Chuluunbat Tsengelmaa
- Cieslik Krzysztof
- Clark Antony
- Cockcroft Ruellyn L.
- Coleoni Suarez Maria Estela
- Comsa Codruta
- Correa Llano Maria G.
- Corson Timothy W.
- Couitchere Line
- Cowan-Lyn Kristin E.
- Csoka Monika
- Dangboon Wantanee
- Das Anirban
- Das Pranab
- Das Sima
- Davanzo Jacquelyn M.
- Davidson Alan
- De Francesco Sonia
- De Potter Patrick
- Demirci Hakan
- Desjardins Laurence
- Diaz Coronado Rosdali Y.
- Dimaras Helen
- Dodgshun Andrew J.
- Donato Macedo Carla R.
- Dragomir Monica D.
- Du Bruyn Magritha
- Du Plessis Johannes
- Du Yi
- Dudeja Gagan
- Eerme Katrin
- El Kettani Asmaa
- Elbahi Amal M.
- Elder James E.
- Elhaddad Alaa M.
- Elhassan Moawia M. A.
- Elzembely M.
- Ericksen Connor
- Essuman Vera A.
- Evina Ted Grimbert A.
- Ezegwui Ifeoma R.
- Fabian Ido Didi
- Fadoo Zehra
- Fandino Adriana C.
- Faranoush Mohammad
- Fasina Oluyemi
- Fernandez Delia D. P. G.
- Fernandez-Teijeiro Ana
- Foster Allen
- Frenkel Shahar
- Fu Ligia D.
- Fuentes-Alabi Soad L.
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- Ghassemi Fariba
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- Gole Glen A.
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- Gonzalez Efren
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- Gorfine Malka
- Graells Jaime
- Gregersen Pernille A.
- Grigorovski Nathalia D. A. K.
- Groznik Alenka Lavric
- Guedenon Koffi M.
- Gunasekera D. Sanjeeva
- Gunduz Ahmet K.
- Gupta Himika
- Gupta Sanjiv
- Gupta Vineeta
- Hadjistilianou Theodora
- Hamel Patrick
- Hamid Syed A.
- Hamzah Norhafizah
- Hansen Eric D.
- Harbour J. William
- Hartnett M. Elizabeth
- Hasanreisoglu Murat
- Hassan Muhammad
- Hassan Sadiq
- Hassan Shadab
- Hautz Wojciech
- Haydar Huda
- Hederova Stanislava
- Hessissen Laila
- Hongeng Suradej
- Hordofa Diriba F.
- Hubbard G. Baker
- Hummelen Marlies
- Husakova Kristina
- Ibanga Affiong
- Ida Russo
- Ilic Vesna R.
- Islamov Ziyavuddin
- Jairaj Vivekaraj
- Janjua Teyyeb
- Jeeva Irfan
- Ji Xunda
- Jo Dong Hyun
- Jones Michael M.
- Kabore Rolande L.
- Kaliki Swathi
- Kalinaki Abubakar
- Kamsang Pius
- Kantar Mehmet
- Kapelushnik Noa
- Kardava Tamar
- Kebudi Rejin
- Keomisy Jonny
- Kepak Tomas
- Ketteler Petra
- Khan Zohora
- Khaqan Hussain A.
- Khetan Vikas
- Khodabande Alireza
- Khotenashvili Zaza
- Kim Jeong Hun
- Kim Jonathan W.
- Kiratli Hayyam
- Kivela Tero T.
- Klett Artur
- Koc Irem
- Krivaitiene Dalia
- Kruger Mariana
- Kulvichit Kittisak
- Kuntorini Mayasari W.
- Kyara Alice
- Lam Geoffrey C.
- Larson Scott A.
- Latinovic Slobodanka
- Laurenti Kelly D.
- Lavy Yotam
- Leverant Amy A.
- Li Cairui
- Li Kaijun
- Limbu Ben
- Liu Chun-Hsiu
- Lopez Juan P.
- Lukamba Robert M.
- Luna-Fineman Sandra
- Lutfi Delfitri
- Lysytsia Lesia
- Madgar Shiran
- Magrath George N.
- Mahajan Amita
- Maitra Puja
- Maka Erika
- Makimbetov Emil K.
- Maktabi Azza
- Maldonado Carlos
- Mallipatna Ashwin
- Manudhane Rebecca
- Manzhuova Lyazat
- Martin-Begue Nieves
- Masud Sidra
- Matende Ibrahim O.
- Mattosinho Clarissa C. D. S.
- Matua Marchelo
- Mayet Ismail
- Mbumba Freddy B.
- McKenzie John D.
- Mehrvar Azim
- Mengesha Aemero A.
- Menon Vikas
- Mercado Gary John, V
- Mets Marilyn B.
- Midena Edoardo
- Miller Audra
- Mishra Divyansh K. C.
- Mndeme Furahini G.
- Mohamedani Ahmed A.
- Mohammad Mona T.
- Moll Annette C.
- Montero Margarita M.
- Moreira Claude
- Mruthyunjaya Prithvi
- Msina Mchikirwa S.
- Msukwa Gerald
- Mudaliar Sangeeta S.
- Muma Kangwa I. M.
- Munier Francis L.
- Murray Timothy G.
- Musa Kareem O.
- Mushtaq Asma
- Musika Anne A.
- Mustak Hamzah
- Mustapha Tajudeen
- Muyen Okwen M.
- Myezo Khumo H.
- Naidu Gita
- Naidu Natasha
- Nair Akshay Gopinathan
- Natarajan Sundaram
- Naumenko Larisa
- Nency Yetty M.
- Neroev Vladimir
- Ng Yvonne
- Nikitovic Marina
- Nkanga Elizabeth D.
- Nkumbe Henry E.
- Numbi Marcel N.
- Nummi Kalle
- Nuruddin Murtuza
- Nyaywa Mutale
- Nyirenda Chinsisi
- Obono-Obiang Ghislaine
- Oliver Scott Cn
- Oporto Joaquin
- Ortega-Hernandez Miriam
- Oscar Alexander H.
- Ossandon Diego
- Pagarra Halimah
- Paintsil Vivian
- Paiva Luisa
- Palanivelu Mahesh Shanmugam
- Palet Jess Elio Kosh Komba
- Papyan Ruzanna
- Parrozzani Raffaele
- Pascual Morales Claudia R.
- Paton Katherine E.
- Pe&apos
- Peralta Calvo Jesus
- Perez Graciela Gonzalez
- Peric Sanja
- Pham Chau T. M.
- Philbert Remezo
- Plager David A.
- Pochop Pavel
- Polania Rodrigo A.
- Polyakov Vladimir
- Pompe Manca Tekavcic
- Ponce Jimena
- Popovic Maja Beck
- Qadir Ali O.
- Qayyum Seema
- Qian Jiang
- Quah BoonLong
- Quintero D Karina
- Rahman Ardizal
- Rajkarnikar Purnima
- Ramanjulu Rajesh
- Ramasubramanian Aparna
- Ramirez-Ortiz Marco A.
- Randhawa Jasmeen K.
- Randrianarisoa Hoby Lalaina
- Raobela Lea
- Rashid Riffat
- Reddy M. Ashwin
- Refaeli David
- Renner Lorna A.
- Reynders David
- Ribadu Dahiru
- Ritter-Sovinz Petra
- Rogowska Anna
- Rojanaporn Duangnate
- Romero Livia
- Roth Paule Aida Ndoye
- Roy Soma R.
- Saab Raya H.
- Saakyan Svetlana
- Sabhan Ahmed H.
- Sagoo Mandeep S.
- Said Azza M. A.
- Saiju Rohit
- Salas Beatriz
- San Roman Pacheco Sonsoles
- Sanchez Orozco Alma Janeth
- Sanchez Gissela L.
- Sayalith Phayvanh
- Scanlan Trish A.
- Schlueter Sabrina
- Schwab Christoph
- Sedaghat Ahad
- Seth Rachna
- Sgroi Mariana
- Shah Ankoor S.
- Shakoor Shawkat A.
- Sharma Manoj K.
- Sherief Sadik T.
- Shields Carol L.
- Sia David
- Siddiqui Sorath Noorani
- Silva Sonia
- Singh Arun D.
- Singh Usha
- Singha Penny
- Sitorus Rita S.
- Skalet Alison H.
- Soebagjo Hendrian D.
- Sorochynska Tetyana
- Ssali Grace
- Stacey Andrew W.
- Staffieri Sandra E.
- Stahl Erin D.
- Steinberg David M.
- Stones David K.
- Strahlendorf Caron
- Sultana Sadia
- Sun Xiantao
- Superstein Rosanne
- Supriyadi Eddy
- Surukrattanaskul Supawan
- Sutyawan I. Wayan Eka
- Suzuki Shigenobu
- Svojgr Karel
- Sylla Fatoumata
- Tamamyan Gevorg
- Tan Deborah
- Tandili Alketa
- Tang Jing
- Tarrillo Leiva Fanny F.
- Tashvighi Maryam
- Tateshi Bekim
- Teh Kok Hoi
- Tehuteru Edi S.
- Teixeira Luiz F.
- Thawaba Abdullah Dahan M.
- Theophile Tuyisabe
- Toledano Helen
- Trang Doan L.
- Traore Fousseyni
- Tripathy Devjyoti
- Tuncer Samuray
- Tyau-Tyau Harba
- Umar Ali B.
- Unal Emel
- Uner Ogul E.
- Urbak Steen F.
- Ushakova Tatiana L.
- Usmanov Rustam H.
- Valeina Sandra
- Valente Paola
- Vasquez Anchaya Jacqueline Karina
- Vaughan Leon O.
- Veleva-Krasteva Nevyana V.
- Verma Nishant
- Victor Andi A.
- Viksnins Maris
- Villacis Chafla Edwin G.
- Villegas Victor M.
- Vishnevskia-Dai Victoria
- Waddell Keith
- Wali Amina H.
- Wang Yi-Zhuo
- Wangtiraumnuay Nutsuchar
- Wetter Julie
- Widiarti Widiarti
- Wijsard Milo van Hoefen
- Wilson Matthew W.
- Wime Amelia Dc
- Wiwatwongwana Atchareeya
- Wiwatwongwana Damrong
- Wolley Dod Charlotte
- Wong Emily S.
- Wongwai Phanthipha
- Wu Si-qi
- Xiang Daoman
- Xiao Yishuang
- Xu Bing
- Xue Kang
- Yaghy Antonio
- Yam Jason C.
- Yang Huasheng
- Yanga Jenny M.
- Yaqub Muhammad A.
- Yarovaya Vera A.
- Yarovoy Andrey A.
- Ye Huijing
- Yee Roberto, I
- Yousef Yacoub A.
- Yuliawati Putu
- Zapata Lopez Arturo M.
- Zein Ekhtelbenina
- Zhang Yi
- Zhilyaeva Katsiaryna
- Zia Nida
- Ziko Othman A. O.
- Zondervan Marcia
- Publication venue
- Elsevier BV
- Publication date
- 01/08/2022
- Field of study
Background Retinoblastoma is the most common intraocular cancer worldwide. There is some evidence to suggest that major differences exist in treatment outcomes for children with retinoblastoma from different regions, but these differences have not been assessed on a global scale. We aimed to report 3-year outcomes for children with retinoblastoma globally and to investigate factors associated with survival. Methods We did a prospective cluster-based analysis of treatment-naive patients with retinoblastoma who were diagnosed between Jan 1,2017, and Dec 31,2017, then treated and followed up for 3 years. Patients were recruited from 260 specialised treatment centres worldwide. Data were obtained from participating centres on primary and additional treatments, duration of follow-up, metastasis, eye globe salvage, and survival outcome. We analysed time to death and time to enucleation with Cox regression models. Findings The cohort included 4064 children from 149 countries. The median age at diagnosis was 23.2 months (IQR 11.0-36.5). Extraocular tumour spread (cT4 of the cTNMH classification) at diagnosis was reported in five (0.8%) of 636 children from high-income countries, 55 (5.4%) of 1027 children from upper-middle-income countries, 342 (19. 7%) of 1738 children from lower-middle-income countries, and 196 (42.9%) of 457 children from low-income countries. Enudeation surgery was available for all children and intravenous chemotherapy was available for 4014 (98.8%) of 4064 children. The 3-year survival rate was 99.5% (95% CI 98.8-100.0) for children from high-income countries, 91.2% (89.5-93.0) for children from upper-middle-income countries, 80.3% (78.3-82.3) for children from lower-middle-income countries, and 57.3% (524-63-0) for children from low-income countries. On analysis, independent factors for worse survival were residence in low-income countries compared to high-income countries (hazard ratio 16.67; 95% CI 4.76-50.00), cT4 advanced tumour compared to cT1 (8.98; 4.44-18.18), and older age at diagnosis in children up to 3 years (1.38 per year; 1.23-1.56). For children aged 3-7 years, the mortality risk decreased slightly (p=0.0104 for the change in slope). Interpretation This study, estimated to include approximately half of all new retinoblastoma cases worldwide in 2017, shows profound inequity in survival of children depending on the national income level of their country of residence. In high-income countries, death from retinoblastoma is rare, whereas in low-income countries estimated 3-year survival is just over 50%. Although essential treatments are available in nearly all countries, early diagnosis and treatment in low-income countries are key to improving survival outcomes. Copyright (C) 2022 The Author(s). Published by Elsevier Ltd.Y
Empagliflozin in Patients with Chronic Kidney Disease
- Author
- Aamir Navivala
- Abdulwahab Arbi
- Abegail Hernandez Pena
- Abraham Hanburry
- Adedolapo Adeleke
- Adeera Levin
- Adil Hazara
- Adline Ghazi
- Agnes Masengu
- Ahmad Tuffaha
- Ahmed Awad
- Ahmed Ghanem
- Ai Fukasawa
- Aik Kheng Lee
- Aiko Terakawa
- Aiko Tomita
- Aiko Yamada
- Ailsa Geddes
- Airi Sato
- Akane Katanosaka
- Akane Yamamoto
- Akihiro Fujimoto
- Akihiro Katayama
- Akihito Tanaka
- Akiko Fujita
- Akiko Hashimoto
- Akiko Ishiguro
- Akiko Omata
- Akimasa Asai
- Akinwande Akinfolarin
- Akio Kanazawa
- Akiyo Nishiyama
- Akiyo Tanabe
- Alastair Rankin
- Alastair Woodman
- Albert Hing
- Albert Power
- Alberto Rosati
- Aldo P Maggioni
- Aldo Peixoto
- Aleksandra Murawska
- Alessandro D'Amelio
- Alex Aguilera
- Alex Baxter
- Alex Howson
- Alexa Wonnacott
- Alexander Hadley
- Alexander Hodakowski
- Alexander Paliege
- Alexis Africano
- Alexis Stevenson
- Alfio Giuffrida
- Alfred K Cheung
- Alia Hasan
- Alia Zubaidah Bahtar
- Alice Aitken
- Alice Guerini
- Aliseiya Garza
- Alison Cowley
- Alison Jenkins
- Alison Timadjer
- Allen Young
- Allison Leslie
- Amalia Caamano
- Amanda Aliu
- Amanda Axler
- Amanda Davis
- Amanda Scott
- Amanda Tyler
- Amar Ali
- Amber Avery
- Amber Hurst
- Amelia Te
- Ami Inamori
- Amin Oomatia
- Amir Kazory
- Amret Hawfield
- Amritanshu Pandey
- Amy Hudson
- Amy Hunter
- Amy Mottl
- Ana Moncada
- Anand Srivastava
- Anastassiya Reisler
- Anca Gherman
- Andre Valleteau
- Andrea Lorimer
- Andrea Schwab
- Andrea Webster
- Andrea Wilson
- Andreas Schneider
- Andrew Breach
- Andrew Connor
- Andrew Frankel
- Andrew Gordon
- Andrew Lewington
- Andrew Shepherd
- Andrew Steele
- Andy Burke
- Andy Measor
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- Angela Chamberlain
- Angela Field
- Angela Moon
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- Angharad Williams
- Anil George
- Anita Hepditch
- Anita Kamarzarian
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- Anju Oommen
- Anke Torp
- Ankit Mehta
- Ann Bennett
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- Annalisa Aloisi
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- Arash Rashidi
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- Arihiro Kiyosue
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- Ashleigh Wheeler
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- Auguste Kutschat
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- Bhupinder Grewal
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- Sina Rolfsmeier
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- Siti Nabilah Mohamad Zaini
- Smeeta Sinha
- Smita Gunda
- Sodai Kubota
- Sofia Dayi
- Sonja Grotjahn
- Sonoka Yamamoto
- Soo Kun Lim
- Soon Yi Sor
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- Sri Yarlagadda
- Sridhar Ramanaidu
- Srinivasan Beddhu
- Stacey-Ann Villaruel
- Stacie Hitchcock
- Stacy Gillham
- Staplin Natalie
- Stefan Degenhardt
- Stefan Haack
- Stefan Hantel
- Stefanie Jones
- Stefanie Kuhn
- Stephan Matthias
- Stephanie Bolton
- Stephanie Estcourt
- Stephanie Evans
- Stephanie Martinez
- Stephanie Rosenberg
- Stephanie Watson
- Stephanie Whittaker
- Stephany Topping
- Stephen Aronoff
- Steubl Dominik
- Steven Nagelberg
- Stevens Will
- Stewart Moffat
- Subash Somalanka
- Subha Clarke
- Subrata Debnath
- Sucharit Joshi
- Sue Ann Lee
- Sue Hewins
- SueAnn Squyres
- Sui Phin Kon
- Sunil Bhandari
- Sunita Bavanandan
- Suresh Ramadoss
- Suria Junus
- Susan Haskett
- Susan Hurley
- Susan McLaughlin
- Susannah Pajak
- Susanne Bodine
- Susanne Brenner
- Susumu Nakatani
- Suzannah Dorey
- Sybille Merscher
- Tabbatha Duck
- Tabinda Dugal
- Tadahiro Tomita
- Taeko Uchida
- Tai Meng Chen
- Takahiro Ishikawa
- Takahiro Kato
- Takahiro Matsunaga
- Takahiro Yamano
- Takako Kuramae
- Takako Ozawa
- Takanori Hyo
- Takashi Funayama
- Takashi Kadowaki
- Takashi Kobayashi
- Takashi Udagawa
- Takatoshi Otani
- Takayuki Katsuno
- Takehiko Wada
- Takehiro Sugiyama
- Takeshi Kurose
- Takeshi Miyatsuka
- Takeshi Ogihara
- Takuji Ishimoto
- Takuma Kojo
- Takuya Haraguchi
- Takuya Yokoyama
- Tamaki Sasaki
- Tamara Isakova
- Tammi Glider
- Tammy Ross
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- The EMPA-KIDNEY Collaborative Group: Colin Baigent
- Theresa McCarthy
- Thiemo Pfab
- Thisun Saram
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- Thomas Pickett
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- Thomas Walters
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- Tina Harding
- Tina Ramsey
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- Tingting Kan
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- Toluleyi Sobande
- Tomoe Sato
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- Tomohito Gohda
- Tomohito Izumi
- Tomoka Nakamura
- Tomoki Kosugi
- Tomoko Hisatake
- Tomoko Morisaki
- Tomoko Takahashi
- Tomoko Takai
- Tomonori Hasegawa
- Tomoya Mita
- Torsten Schramm
- Toru Ikeda
- Toshiki Kano
- Toshimasa Yamauchi
- Toshiya Yamamoto
- Toshiyuki Komiya
- Toyoyoshi Uchida
- Tracey Cummins
- Tracy Fuller
- Tracy Spinola
- Trevor Greene
- Tricia Young
- Tristan Daniels
- Tsukasa Iwakura
- Tuttle Katherine R
- Tze Jian Ng
- Ulla Ludwig
- Ulrike Giebeln-Hudnell
- Ulrike Schmidt
- Urs Benck
- Ursula Hohenstatt
- Usah Lilavivat
- Vahid Mahabadi
- Vanessa Rivers
- Verlaine Stewart-Ray
- Veronica Poma
- Veronica Yousif
- Vesta Lai
- Vicki Adell
- Vicki Brindle
- Vicki Dodds
- Vicki Donley
- Vickie Jones
- Victoria Carnall
- Victoria Gonce
- Vimal Derebail
- Vinay Varad
- Vittorio Ortalda
- Vivian Yiu
- Vladimir Cejka
- Volker Schettler
- Volker Vielhauer
- Wael Eid
- Wagdy Basily
- Wakako Isari
- Wallendszus Karl
- Waltraud Kmietschak
- Wan Ahmad Faizal Alaidin Razali
- Wan Hazlina Wan Mohamad
- Wanner Christoph
- Waqar Ayub
- Waseem Karsan
- Wasim Deeb
- Wasim Hanif
- Wataru Ogawa
- Wei Wang
- Wei Wei
- Weijing Bian
- Weiping Hou
- Weixin Kong
- Wen Jiun Liu
- Wen Liu
- Wendy Arriaga
- Wiebke Kaluza-Schilling
- Will Stevens
- William Durham
- William G Herrington
- William G Herrington
- William Hodge
- William Petchey
- Wolf-Adam Seeger
- Wolfgang Seeger
- Wuhanbilige Hundei
- Xavier Rossello
- Xia Song
- Xiangcheng Xiao
- Xiaojing Jiao
- Xiaojue Li
- Xiaoliang Wang
- Xinzhou Zhang
- Xiumei Hu
- Xuejiao Liu
- Xueying Wang
- Yan Li
- Yanmei Xu
- Yanping Wang
- YanRu Qiao
- Yanwu Yu
- Yanyun Xie
- Yao Weng
- Yao Yao
- Yasemin Kavak
- Yasuhiko Furukawa
- Yasuhiko Ito
- Yasuhiko Kanaguchi
- Yasuhiro Suzuki
- Yasushi Iwaita
- Ye Mun Low
- Yee Yan Lee
- Yew Fong Liew
- Yi Loon Tye
- Yik Hong Wong
- Yik Shen Lim
- Ying Hu
- Ying Jiang
- Ying Kuan
- Ying Lu
- Yinghua Chen
- Yohei Ejima
- Yoko Inukai
- Yolanda Miller
- Yong Chieh Chan
- Yonghong Bu
- Yoshiaki Morishita
- Yoshie Shibata
- Yoshifumi Tamura
- Yoshihiko Yamasaki
- Yoshihisa Wada
- Yoshikazu Tamori
- Yoshiki Suzuki
- Yoshimitsu Yamasaki
- Yoshinari Yasuda
- Yoshinori Osaki
- Yoshiro Kato
- Yoshiyuki Hamamoto
- Yosuke Hirakawa
- Yosuke Nakagawa
- Youcef Mostefai
- Young Lee-Barkey
- Yu An
- Yu Chen
- Yu Chen Ong
- Yu Yamanouchi
- Yuana Mohd Yusoff
- Yuichiro Munakata
- Yuji Oe
- Yuka Sato
- Yuka Ueda
- Yukari Miura
- Yuki Fujita
- Yuki Fukao
- Yuki Omori
- Yukihiro Shimizu
- Yukihiro Yamaji
- Yukiko Nakayama
- Yukiko Toyonaga
- Yukiko Wakita
- Yuko Katsuda
- Yuko Makita
- Yuko Okada
- Yuko Orimo
- Yumi Osawa
- Yushi Hirota
- Yusuke Suzuki
- Yutaka Kamimura
- Yuya Nishida
- Yvette Webley
- Yvonne Ehrl
- Yvonne Jackson
- Zabrina Lozon
- Zaid Azhari
- Zaiha Harun
- Zainab Sheriff
- Zanaida Cooper
- Zay Htet
- Zhang Duan Tham
- Zhi-Hong Liu
- Zhirui Zhao
- Zhu Doreen
- Zhuo Tang
- Zohreh Forghani
- Zuber Patel
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2023
- Field of study
Background The effects of empagliflozin in patients with chronic kidney disease who are at risk for disease progression are not well understood. The EMPA-KIDNEY trial was designed to assess the effects of treatment with empagliflozin in a broad range of such patients. Methods We enrolled patients with chronic kidney disease who had an estimated glomerular filtration rate (eGFR) of at least 20 but less than 45 ml per minute per 1.73 m(2) of body-surface area, or who had an eGFR of at least 45 but less than 90 ml per minute per 1.73 m(2) with a urinary albumin-to-creatinine ratio (with albumin measured in milligrams and creatinine measured in grams) of at least 200. Patients were randomly assigned to receive empagliflozin (10 mg once daily) or matching placebo. The primary outcome was a composite of progression of kidney disease (defined as end-stage kidney disease, a sustained decrease in eGFR to < 10 ml per minute per 1.73 m(2), a sustained decrease in eGFR of & GE;40% from baseline, or death from renal causes) or death from cardiovascular causes. Results A total of 6609 patients underwent randomization. During a median of 2.0 years of follow-up, progression of kidney disease or death from cardiovascular causes occurred in 432 of 3304 patients (13.1%) in the empagliflozin group and in 558 of 3305 patients (16.9%) in the placebo group (hazard ratio, 0.72; 95% confidence interval [CI], 0.64 to 0.82; P < 0.001). Results were consistent among patients with or without diabetes and across subgroups defined according to eGFR ranges. The rate of hospitalization from any cause was lower in the empagliflozin group than in the placebo group (hazard ratio, 0.86; 95% CI, 0.78 to 0.95; P=0.003), but there were no significant between-group differences with respect to the composite outcome of hospitalization for heart failure or death from cardiovascular causes (which occurred in 4.0% in the empagliflozin group and 4.6% in the placebo group) or death from any cause (in 4.5% and 5.1%, respectively). The rates of serious adverse events were similar in the two groups. Conclusions Among a wide range of patients with chronic kidney disease who were at risk for disease progression, empagliflozin therapy led to a lower risk of progression of kidney disease or death from cardiovascular causes than placebo