Rebels on trial! The configuration of the enemy in the Comentarios of Álvar Núñez Cabeza de Vaca

En 1545, el segundo gobernador de la provincia del Río de la Plata, Álvar Núñez Cabeza de Vaca, regresa a España engrillado y con catorce pliegos de acusaciones a sus espaldas. Tras un largo pleito, que acaba con la absolución del imputado, Cabeza de Vaca decide contar su versión de los hechos publicando sus Comentarios (1555). Este texto supone el punto final de su defensa, pero también un juicio público que vuelve las tornas y sienta en el banquillo de los acusados a sus enemigos capitales. En este artículo se analizará cómo se configura la imagen de los rebeldes desde una perspectiva que se presenta como única portadora de los valores civilizadores en aquellas lejanas tierras carentes de todo orden conocido.En 1545, el segundo gobernador de la provincia del Río de la Plata, Álvar Núñez Cabeza de Vaca, regresa a España engrillado y con catorce pliegos de acusaciones a sus espaldas. Tras un largo pleito, que acaba con la absolución del imputado, Cabeza de Vaca decide contar su versión de los hechos publicando sus Comentarios (1555). Este texto supone el punto final de su defensa, pero también un juicio público que vuelve las tornas y sienta en el banquillo de los acusados a sus enemigos capitales. En este artículo se analizará cómo se configura la imagen de los rebeldes desde una perspectiva que se presenta como única portadora de los valores civilizadores en aquellas lejanas tierras carentes de todo orden conocido.In 1545, the second governor of the province of the Rio de la Plata, Álvar Núñez Cabeza de Vaca, returns in shackles to Spain with fourteen sheets full of accusations. After a long litigation that finally ends with the absolution of the accused, Cabeza de Vaca decides to share his version publishing his Comentarios (1555). This text is the final point of his defense, but also a public process that turn the tables on his foremost enemies sending them to the bench of the accused. This paper will analyze how the rebels' image is set from the point of view that represents the only owner of civilizing powers in those far away lawless lands

Accounting Problems Under the Excess Profits Tax

DNA vaccines based on subunits from pathogens have several advantages over other vaccine strategies. DNA vaccines can easily be modified, they show good safety profiles, are stable and inexpensive to produce, and the immune response can be focused to the antigen of interest. However, the immunogenicity of DNA vaccines which is generally quite low needs to be improved. Electroporation and co-delivery of genetically encoded immune adjuvants are two strategies aiming at increasing the efficacy of DNA vaccines. Here, we have examined whether targeting to antigen-presenting cells (APC) could increase the immune response to surface envelope glycoprotein (Env) gp120 from Human Immunodeficiency Virus type 1 (HIV- 1). To target APC, we utilized a homodimeric vaccine format denoted vaccibody, which enables covalent fusion of gp120 to molecules that can target APC. Two molecules were tested for their efficiency as targeting units: the antibody-derived single chain Fragment variable (scFv) specific for the major histocompatilibility complex (MHC) class II I-E molecules, and the CC chemokine ligand 3 (CCL3). The vaccines were delivered as DNA into muscle of mice with or without electroporation. Targeting of gp120 to MHC class II molecules induced antibodies that neutralized HIV-1 and that persisted for more than a year after one single immunization with electroporation. Targeting by CCL3 significantly increased the number of HIV-1 gp120-reactive CD8(+) T cells compared to non-targeted vaccines and gp120 delivered alone in the absence of electroporation. The data suggest that chemokines are promising molecular adjuvants because small amounts can attract immune cells and promote immune responses without advanced equipment such as electroporation.Funding Agencies|Research Council of Norway; Odd Fellow</p

Slip-Flow and Heat Transfer of a Non-Newtonian Nanofluid in a Microtube

The slip-flow and heat transfer of a non-Newtonian nanofluid in a microtube is theoretically studied. The power-law rheology is adopted to describe the non-Newtonian characteristics of the flow, in which the fluid consistency coefficient and the flow behavior index depend on the nanoparticle volume fraction. The velocity profile, volumetric flow rate and local Nusselt number are calculated for different values of nanoparticle volume fraction and slip length. The results show that the influence of nanoparticle volume fraction on the flow of the nanofluid depends on the pressure gradient, which is quite different from that of the Newtonian nanofluid. Increase of the nanoparticle volume fraction has the effect to impede the flow at a small pressure gradient, but it changes to facilitate the flow when the pressure gradient is large enough. This remarkable phenomenon is observed when the tube radius shrinks to micrometer scale. On the other hand, we find that increase of the slip length always results in larger flow rate of the nanofluid. Furthermore, the heat transfer rate of the nanofluid in the microtube can be enhanced due to the non-Newtonian rheology and slip boundary effects. The thermally fully developed heat transfer rate under constant wall temperature and constant heat flux boundary conditions is also compared

Optimal synthesis and characterization of Ag nanofluids by electrical explosion of wires in liquids

Silver nanoparticles were produced by electrical explosion of wires in liquids with no additive. In this study, we optimized the fabrication method and examined the effects of manufacturing process parameters. Morphology and size of the Ag nanoparticles were determined using transmission electron microscopy and field-emission scanning electron microscopy. Size and zeta potential were analyzed using dynamic light scattering. A response optimization technique showed that optimal conditions were achieved when capacitance was 30 μF, wire length was 38 mm, liquid volume was 500 mL, and the liquid type was deionized water. The average Ag nanoparticle size in water was 118.9 nm and the zeta potential was -42.5 mV. The critical heat flux of the 0.001-vol.% Ag nanofluid was higher than pure water

Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at √ s = 8 TeV with the ATLAS detector

Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fb−1 of √ s = 8 TeV data collected in 2012 with the ATLAS detector at the LHC. Events are required to have at least one jet with pT > 120 GeV and no leptons. Nine signal regions are considered with increasing missing transverse momentum requirements between Emiss T > 150 GeV and Emiss T > 700 GeV. Good agreement is observed between the number of events in data and Standard Model expectations. The results are translated into exclusion limits on models with either large extra spatial dimensions, pair production of weakly interacting dark matter candidates, or production of very light gravitinos in a gauge-mediated supersymmetric model. In addition, limits on the production of an invisibly decaying Higgs-like boson leading to similar topologies in the final state are presente

Ovarian cancer molecular pathology.

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