Two-stage hybrid feature selection algorithms for diagnosing erythemato-squamous diseases

This paper proposes two-stage hybrid feature selection algorithms to build the stable and efficient diagnostic models where a new accuracy measure is introduced to assess the models. The two-stage hybrid algorithms adopt Support Vector Machines (SVM) as a classification tool, and the extended Sequential Forward Search (SFS), Sequential Forward Floating Search (SFFS), and Sequential Backward Floating Search (SBFS), respectively, as search strategies, and the generalized F-score (GF) to evaluate the importance of each feature. The new accuracy measure is used as the criterion to evaluated the performance of a temporary SVM to direct the feature selection algorithms. These hybrid methods combine the advantages of filters and wrappers to select the optimal feature subset from the original feature set to build the stable and efficient classifiers. To get the stable, statistical and optimal classifiers, we conduct 10-fold cross validation experiments in the first stage; then we merge the 10 selected feature subsets of the 10-cross validation experiments, respectively, as the new full feature set to do feature selection in the second stage for each algorithm. We repeat the each hybrid feature selection algorithm in the second stage on the one fold that has got the best result in the first stage. Experimental results show that our proposed two-stage hybrid feature selection algorithms can construct efficient diagnostic models which have got better accuracy than that built by the corresponding hybrid feature selection algorithms without the second stage feature selection procedures. Furthermore our methods have got better classification accuracy when compared with the available algorithms for diagnosing erythemato-squamous diseases

A Novel Soft Computing Based Model For Symptom Analysis & Disease Classification

In countries like India, many mortality occurs every year because of improper pronouncement of disease on time. Many people remain deprived of medication as the people per doctor ratio are nearly 1:1700. Every human body and its physiological processes show some symptoms of a diseased condition. The proposed model in this paper would analyze those symptoms for identification of the disease and its type. In this proposed model, few selected attributes would be considered which are shown as symptoms by a person suspected with a particular disease. Those attributes can be taken as input for the proposed symptom analysis and classification model, which is a soft computing model for classifying a sample first to be diseased or disease free and then, if diseased, predicting its type (if any). Number of diseased and disease free samples are to be collected. Each of these samples is a collection of attributes shown / expressed by a human body. With respect to a specific disease, those collected samples form two primary clusters, one is diseased and the other one is disease free. The disease free cluster may be discarded for further analysis. Depending on the symptoms shown by the diseased samples, every disease has some types based on the symptoms it shows. The diseased cluster of samples can reform clusters among themselves depending on the types of the disease. Those clusters then become the classes of the multiclass classifier for analysis of a new incoming sample

Differential diagnosis of Erythmato-Squamous Diseases using classification and regression tree

Introduction: Differential diagnosis of Erythmato-Squamous Diseases (ESD) is a major challenge in the field of dermatology. The ESD diseases are placed into six different classes. Data mining is the process for detection of hidden patterns. In the case of ESD, data mining help us to predict the diseases. Different algorithms were developed for this purpose. Objective: we aimed to use the Classification and Regression Tree (CART) to predict differential diagnosis of ESD. Methods: we used the Cross Industry Standard Process for Data Mining (CRISP-DM) methodology. For this purpose, the dermatology data set from machine learning repository, UCI was obtained. The Clementine 12.0 software from IBM Company was used for modelling. In order to evaluation of the model we calculate the accuracy, sensitivity and specificity of the model. Results: The proposed model had an accuracy of 94.84 (Standard Deviation: 24.42) in order to correct prediction of the ESD disease. Conclusions: Results indicated that using of this classifier could be useful. But, it would be strongly recommended that the combination of machine learning methods could be more useful in terms of prediction of ESD. © 2016 Keivan Maghooli, Mostafa Langarizadeh, Leila Shahmoradi, Mahdi Habibi-koolaee, Mohamad Jebraeily, and Hamid Bouraghi

An Intelligent Computer-Aided Scheme for Classifying Multiple Skin Lesions

Skin diseases cases are increasing on a daily basis and are difficult to handle due to the global imbalance between skin disease patients and dermatologists. Skin diseases are among the top 5 leading cause of the worldwide disease burden. To reduce this burden, computer-aided diagnosis systems (CAD) are highly demanded. Single disease classification is the major shortcoming in the existing work. Due to the similar characteristics of skin diseases, classification of multiple skin lesions is very challenging. This research work is an extension of our existing work where a novel classification scheme is proposed for multi-class classification. The proposed classification framework can classify an input skin image into one of the six non-overlapping classes i.e., healthy, acne, eczema, psoriasis, benign and malignant melanoma. The proposed classification framework constitutes four steps, i.e., pre-processing, segmentation, feature extraction and classification. Different image processing and machine learning techniques are used to accomplish each step. 10-fold cross-validation is utilized, and experiments are performed on 1800 images. An accuracy of 94.74% was achieved using Quadratic Support Vector Machine. The proposed classification scheme can help patients in the early classification of skin lesions.</p

A Novel Clinical Decision Support System Using Improved Adaptive Genetic Algorithm for the Assessment of Fetal Well-Being

A novel clinical decision support system is proposed in this paper for evaluating the fetal well-being from the cardiotocogram (CTG) dataset through an Improved Adaptive Genetic Algorithm (IAGA) and Extreme Learning Machine (ELM). IAGA employs a new scaling technique (called sigma scaling) to avoid premature convergence and applies adaptive crossover and mutation techniques with masking concepts to enhance population diversity. Also, this search algorithm utilizes three different fitness functions (two single objective fitness functions and multi-objective fitness function) to assess its performance. The classification results unfold that promising classification accuracy of 94% is obtained with an optimal feature subset using IAGA. Also, the classification results are compared with those of other Feature Reduction techniques to substantiate its exhaustive search towards the global optimum. Besides, five other benchmark datasets are used to gauge the strength of the proposed IAGA algorithm

A new model for iris data set classification based on linear support vector machine parameter's optimization

Data mining is known as the process of detection concerning patterns from essential amounts of data. As a process of knowledge discovery. Classification is a data analysis that extracts a model which describes an important data classes. One of the outstanding classifications methods in data mining is support vector machine classification (SVM). It is capable of envisaging results and mostly effective than other classification methods. The SVM is a one technique of machine learning techniques that is well known technique, learning with supervised and have been applied perfectly to a vary problems of: regression, classification, and clustering in diverse domains such as gene expression, web text mining. In this study, we proposed a newly mode for classifying iris data set using SVM classifier and genetic algorithm to optimize c and gamma parameters of linear SVM, in addition principle components analysis (PCA) algorithm was use for features reduction

Development of Rule-Based Diagnostic Algorithms with Artificial Intelligence Methods to Identify Papulosquamous Diseases

Papüloskuamöz deri hastalıkları halk arasında oldukça sık rastlanan ve kendine has morfolojik özellikleri olan deri hastalıkları grubudur. Papüloskuamöz deri hastalıklarının alt gruplarının belirtileri birbirine çok yakın olduğu için teşhis süreci bazı durumlarda zahmetlidir. Hastalığın teşhisi klinik muayenede konulabilir. Klinik muayenenin yetersiz olduğu durumlarda, tanı deri biyopsisi ile histopatolojik değerlendirme ile konulmaktadır. Bu süreçte dermatolog ve patoloğun uyumlu bir şekilde çalışması ve her iki hekimin de teşhis süreci ile ilgili bilgi birikiminin iyi olması gerekir. Bu yüzden Papüloskuamöz deri hastalıklarının tanısı deri biyopsisine ihtiyaç duyulmadan sadece klinik muayene ile dematolog tarafından konulabilmesi için daha basit, yüksek başarı oranına sahip ve klinikte kullanılabilir yöntemlere ihtiyaç duyulmaktadır. Bu çalışmanın amacı Papüloskuamöz deri hastalıklarının yüksek başarı oranı ile tespit edebilecek, klinikte dermatolog tarafından kullanılabilecek, yapay zeka yöntemleriyle geliştirilmiş kural tabanlı algoritma geliştirmektir. Çalışma kapsamında daha önce toplanmış veri seti kullanılmıştır. Veri setinde Papüloskuamöz deri hastalıklarının altı farklı alt grubu için klinik ve histopatolojik bulgular bulunmaktadır. Öncelikle veri seti ikişer sınıflı olacak şekilde gruplandırılmıştır. Daha sonra özellik seçme algoritmalarıyla klinik ve histopatolojik bulgular seçilmiştir. Daha sonra karar ağaçları yardımıyla kural tabanlı teşhis algoritmaları oluşturulmuştur. Çalışma sonucunda, sadece seçilmiş klinik bulgular kullanılarak ortalama %82.98 doğruluk oranı, 0.89 duyarlılık, 0.76 özgüllük oranıyla Papüloskuamöz deri hastalıkları kural tabanlı algoritmalar geliştirilmiştir. Sonuç olarak, bu çalışmada elde edilen sonuçlara göre, çalışma kapsamında geliştirilen algoritmalar, Papüloskuamöz deri hastalıklarının teşhisi için yapay zeka yöntemleriyle geliştirilen yüksek doğruluk oranına sahip kural tabanlı algoritmalar klinikte kullanılabilir.Papulosquamous skin diseases are common skin diseases and have morphological features. The diagnosis process_x000D_ is sometimes troublesome, as the symptoms of the subgroups of papulosquamous skin diseases are very close to_x000D_ each other. The diagnosis of the disease can be made at the clinical examination. In cases where the clinical_x000D_ examination is insufficient, the diagnosis is made by histopathological evaluation by skin biopsy. In this process,_x000D_ dermatologists and pathologists should work in harmony, and both doctors should have a good knowledge of the_x000D_ diagnosis process. Therefore, more uncomplicated, higher success rate, and clinically practical methods are needed_x000D_ in order for Papulosquamous skin diseases to be established only by a clinical examination by a dermatologist_x000D_ without the need for a skin biopsy. This study aims to develop a rule-based algorithm that can detect_x000D_ Papulosquamous skin diseases with a high success rate, can be used by dermatologists in the clinic, developed_x000D_ with artificial intelligence methods. Within the scope of the study, the previously collected data set was used. The_x000D_ data set contains clinical and histopathological findings for six different subgroups of Papulosquamous skin_x000D_ diseases. Firstly, the data set is grouped into two classes. Then, clinical and histopathological findings were_x000D_ selected with feature selection algorithms. Then, rule-based diagnostic algorithms were created with the help of_x000D_ decision trees. As a result of the study, Papulosquamous skin diseases rule-based algorithms have been developed_x000D_ with an average of 82.98% accuracy rate, 0.89 sensitivity, and 0.76 specificity rate using only selected clinical_x000D_ findings. Consequently, according to the results obtained in this study, algorithms developed within the scope of_x000D_ the study, high-accuracy rule-based algorithms developed with artificial intelligence methods can be used in the_x000D_ clinic for the diagnosis of Papulosquamous skin diseases.In job-shop production systems, orders are assigned to work centers according to their routes, and their operations are performed in this order. Production is becoming more and more complex with the increasing number of product lines and work centers with different routes. Decisions to be made according to the realtime monitoring of a dynamic production environment have become important. With the Fourth Industrial Revolution, information technologies are widely used in industries. A large amount of data is obtained from production tools that are capable of communicating with each other by means of Industry 4.0 and the internet of things. In this study, a simulation model of a production system that can collect data in real-time via sensors in work centers has been created and operation conditions have been determined. Then, work center / machine loading strategies were compared according to the delay periods of the jobs. The simulation model with the best loading strategy was run according to three different demand rates. Then data related with the delay status of the orders and the status of the work centers was obtained. The data were evaluated with data mining classification algorithms and rules were determined for delayed jobs. These rules were added to the simulation model as a decision mechanism. When an order is received in this model, the expert system estimates whether or not there will be a delay, and makes a decision to outsource the order’s production if needed. This approach further reduces the number of delayed order

Papüloskuamöz Hastalıkların Belirlenmesi için Yapay Zeka Yöntemleriyle Kural Tabanlı Teşhis Algoritmalarının Geliştirilmesi

Papüloskuamöz deri hastalıkları halk arasında oldukça sık rastlanan ve kendine has morfolojik özellikleri olan deri hastalıkları grubudur. Papüloskuamöz deri hastalıklarının alt gruplarının belirtileri birbirine çok yakın olduğu için teşhis süreci bazı durumlarda zahmetlidir. Hastalığın teşhisi klinik muayenede konulabilir. Klinik muayenenin yetersiz olduğu durumlarda, tanı deri biyopsisi ile histopatolojik değerlendirme ile konulmaktadır. Bu süreçte dermatolog ve patoloğun uyumlu bir şekilde çalışması ve her iki hekimin de teşhis süreci ile ilgili bilgi birikiminin iyi olması gerekir. Bu yüzden Papüloskuamöz deri hastalıklarının tanısı deri biyopsisine ihtiyaç duyulmadan sadece klinik muayene ile dematolog tarafından konulabilmesi için daha basit, yüksek başarı oranına sahip ve klinikte kullanılabilir yöntemlere ihtiyaç duyulmaktadır. Bu çalışmanın amacı Papüloskuamöz deri hastalıklarının yüksek başarı oranı ile tespit edebilecek, klinikte dermatolog tarafından kullanılabilecek, yapay zeka yöntemleriyle geliştirilmiş kural tabanlı algoritma geliştirmektir. Çalışma kapsamında daha önce toplanmış veri seti kullanılmıştır. Veri setinde Papüloskuamöz deri hastalıklarının altı farklı alt grubu için klinik ve histopatolojik bulgular bulunmaktadır. Öncelikle veri seti ikişer sınıflı olacak şekilde gruplandırılmıştır. Daha sonra özellik seçme algoritmalarıyla klinik ve histopatolojik bulgular seçilmiştir. Daha sonra karar ağaçları yardımıyla kural tabanlı teşhis algoritmaları oluşturulmuştur. Çalışma sonucunda, sadece seçilmiş klinik bulgular kullanılarak ortalama %82.98 doğruluk oranı, 0.89 duyarlılık, 0.76 özgüllük oranıyla Papüloskuamöz deri hastalıkları kural tabanlı algoritmalar geliştirilmiştir. Sonuç olarak, bu çalışmada elde edilen sonuçlara göre, çalışma kapsamında geliştirilen algoritmalar, Papüloskuamöz deri hastalıklarının teşhisi için yapay zeka yöntemleriyle geliştirilen yüksek doğruluk oranına sahip kural tabanlı algoritmalar klinikte kullanılabilir

Hybrid ACO and SVM algorithm for pattern classification

Ant Colony Optimization (ACO) is a metaheuristic algorithm that can be used to solve a variety of combinatorial optimization problems. A new direction for ACO is to optimize continuous and mixed (discrete and continuous) variables. Support Vector Machine (SVM) is a pattern classification approach originated from statistical approaches. However, SVM suffers two main problems which include feature subset selection and parameter tuning. Most approaches related to tuning SVM parameters discretize the continuous value of the parameters which will give a negative effect on the classification performance. This study presents four algorithms for tuning the SVM parameters and selecting feature subset which improved SVM classification accuracy with smaller size of feature subset. This is achieved by performing the SVM parameters’ tuning and feature subset selection processes simultaneously. Hybridization algorithms between ACO and SVM techniques were proposed. The first two algorithms, ACOR-SVM and IACOR-SVM, tune the SVM parameters while the second two algorithms, ACOMV-R-SVM and IACOMV-R-SVM, tune the SVM parameters and select the feature subset simultaneously. Ten benchmark datasets from University of California, Irvine, were used in the experiments to validate the performance of the proposed algorithms. Experimental results obtained from the proposed algorithms are better when compared with other approaches in terms of classification accuracy and size of the feature subset. The average classification accuracies for the ACOR-SVM, IACOR-SVM, ACOMV-R and IACOMV-R algorithms are 94.73%, 95.86%, 97.37% and 98.1% respectively. The average size of feature subset is eight for the ACOR-SVM and IACOR-SVM algorithms and four for the ACOMV-R and IACOMV-R algorithms. This study contributes to a new direction for ACO that can deal with continuous and mixed-variable ACO