Terrestrial applications: An intelligent Earth-sensing information system

For Abstract see A82-2214

Generation of a combined dataset of simulated radar and electro-optical imagery

In the world of remote sensing there exist radar sensors and EO/IR sensors, both of which carry with them unique information useful to the imaging community. Radar has the capability of imaging through all types of weather, day or night. EO/IR produces radiance maps and frequently images at much finer resolution than radar. While each of these systems is valuable to imaging, there exists unknown territory in the imaging community as to the value added in combining the best of both these worlds. This work will begin to explore the challenges in simulating a scene in both a radar tool called Xpatch and an EO/IR tool called DIRSIG. The capabilities and limitations inherent to both radar and EO/IR are similar in the image simulation tools, so the work done in a simulated environment will carry over to the real-world environment as well. The synthetic data generated will be compared to existing measured data to demonstrate the validity of the experiment. Future work should explore registration and various types of fusion of the resulting images to demonstrate the synergistic value of the combined images

A Comprehensive Survey of Deep Learning in Remote Sensing: Theories, Tools and Challenges for the Community

In recent years, deep learning (DL), a re-branding of neural networks (NNs), has risen to the top in numerous areas, namely computer vision (CV), speech recognition, natural language processing, etc. Whereas remote sensing (RS) possesses a number of unique challenges, primarily related to sensors and applications, inevitably RS draws from many of the same theories as CV; e.g., statistics, fusion, and machine learning, to name a few. This means that the RS community should be aware of, if not at the leading edge of, of advancements like DL. Herein, we provide the most comprehensive survey of state-of-the-art RS DL research. We also review recent new developments in the DL field that can be used in DL for RS. Namely, we focus on theories, tools and challenges for the RS community. Specifically, we focus on unsolved challenges and opportunities as it relates to (i) inadequate data sets, (ii) human-understandable solutions for modelling physical phenomena, (iii) Big Data, (iv) non-traditional heterogeneous data sources, (v) DL architectures and learning algorithms for spectral, spatial and temporal data, (vi) transfer learning, (vii) an improved theoretical understanding of DL systems, (viii) high barriers to entry, and (ix) training and optimizing the DL.Comment: 64 pages, 411 references. To appear in Journal of Applied Remote Sensin

In Silico Resources to Assist in the Development and Evaluation of Physiologically-Based Kinetic Models

Since their inception in pharmaceutical applications, physiologically-based kinetic (PBK) models are increasingly being used across a range of sectors, such as safety assessment of cosmetics, food additives, consumer goods, pesticides and other chemicals. Such models can be used to construct organ-level concentration-time profiles of xenobiotics. These models are essential in determining the overall internal exposure to a chemical and hence its ability to elicit a biological response. There are a multitude of in silico resources available to assist in the construction and evaluation of PBK models. An overview of these resources is presented herein, encompassing all attributes required for PBK modelling. These include predictive tools and databases for physico-chemical properties and absorption, distribution, metabolism and elimination (ADME) related properties. Data sources for existing PBK models, bespoke PBK software and generic software that can assist in model development are also identified. On-going efforts to harmonise approaches to PBK model construction, evaluation and reporting that would help increase the uptake and acceptance of these models are also discussed

Final Report DE-EE0005380: Assessment of Offshore Wind Farm Effects on Sea Surface, Subsurface and Airborne Electronic Systems

Offshore wind energy is a valuable resource that can provide a significant boost to the US renewable energy portfolio. A current constraint to the development of offshore wind farms is the potential for interference to be caused by large wind farms on existing electronic and acoustical equipment such as radar and sonar systems for surveillance, navigation and communications. The US Department of Energy funded this study as an objective assessment of possible interference to various types of equipment operating in the marine environment where offshore wind farms could be installed. The objective of this project was to conduct a baseline evaluation of electromagnetic and acoustical challenges to sea surface, subsurface and airborne electronic systems presented by offshore wind farms. To accomplish this goal, the following tasks were carried out: (1) survey electronic systems that can potentially be impacted by large offshore wind farms, and identify impact assessment studies and research and development activities both within and outside the US, (2) engage key stakeholders to identify their possible concerns and operating requirements, (3) conduct first-principle modeling on the interactions of electromagnetic signals with, and the radiation of underwater acoustic signals from, offshore wind farms to evaluate the effect of such interactions on electronic systems, and (4) provide impact assessments, recommend mitigation methods, prioritize future research directions, and disseminate project findings. This report provides a detailed description of the methodologies used to carry out the study, key findings of the study, and a list of recommendations derived based the findings

Role of Remote Sensing in Disaster Management

The objective of this report is to review the existing satellites monitoring Earth’s resources and natural disasters. Each satellite has different repeat pass frequency and spatial resolution (unless it belongs to the same series of satellites for the purpose of continuation of data flow with same specifications). Similarly, different satellites have different types of sensors on-board, such as, panchromatic, multispectral, infrared and thermal. All these sensors have applications in disaster mitigation, though depending on the electromagnetic characteristics of the objects on Earth and the nature of disaster itself. With a review of the satellites in orbit and their sensors the present work provides an insight to suitability of satellites and sensors to different natural disasters. For example, thermal sensors capture fire hazards, infrared sensors are more suitable for floods and microwave sensors can record soil moisture. Several kinds of disasters, such as, earthquake, volcano, tsunami, forest fire, hurricane and floods are considered for the purpose of disaster mitigation studies in this report. However, flood phenomenon has been emphasized upon in this study with more detailed account of remote sensing and GIS (Geographic Information Systems) applicability. Examples of flood forecasting and flood mapping presented in this report illustrate the capability of remote sensing and GIS technology in delineating flood risk areas and assessing the damages after the flood recedes. With the help of a case study of the Upper Thames River watershed the use of remote sensing and GIS has been illustrated for better understanding. The case study enables the professionals and planning authorities to realize the impact of urbanization on river flows. As the urban sprawl increases with the increase of population, the rainfall and snow melt reaches the river channels at a faster rate with higher intensity. In other words it can be inferred that through careful land use planning flood disasters can be mitigated.https://ir.lib.uwo.ca/wrrr/1002/thumbnail.jp

Computational Approaches Drive Developments in Immune-Oncology Therapies for PD-1/PD-L1 Immune Checkpoint Inhibitors

Funding Information: This research was funded by Fundação para a Ciência e Tecnologia (FCT) Portugal, grant number UIDB/50006/2020 (LAQV-REQUIMTE), UIDP/04378/2020 and UIDB/04378/2020 (UCIBIO) and LA/P/0140/2020 (i4HB), the European Commission GLYCOTwinning (GA 101079417), the EJPRD ProDGNE (EJPRD/0001/2020 EU 825575) and SI I&DT, DCMatters (AVISO Nº 17/SI/2019) REF 47212. F.P. gratefully acknowledges FCT for an Assistant Research Position (CEECIND/01649/2021). Publisher Copyright: © 2023 by the authors.Computational approaches in immune-oncology therapies focus on using data-driven methods to identify potential immune targets and develop novel drug candidates. In particular, the search for PD-1/PD-L1 immune checkpoint inhibitors (ICIs) has enlivened the field, leveraging the use of cheminformatics and bioinformatics tools to analyze large datasets of molecules, gene expression and protein–protein interactions. Up to now, there is still an unmet clinical need for improved ICIs and reliable predictive biomarkers. In this review, we highlight the computational methodologies applied to discovering and developing PD-1/PD-L1 ICIs for improved cancer immunotherapies with a greater focus in the last five years. The use of computer-aided drug design structure- and ligand-based virtual screening processes, molecular docking, homology modeling and molecular dynamics simulations methodologies essential for successful drug discovery campaigns focusing on antibodies, peptides or small-molecule ICIs are addressed. A list of recent databases and web tools used in the context of cancer and immunotherapy has been compilated and made available, namely regarding a general scope, cancer and immunology. In summary, computational approaches have become valuable tools for discovering and developing ICIs. Despite significant progress, there is still a need for improved ICIs and biomarkers, and recent databases and web tools have been compiled to aid in this pursuit.publishersversionpublishe

Shallow Water Depth Inversion Based on Data Mining Models

This thesis focuses on applying machine-learning algorithms on water depth inversion from remote sensing images, with a case study in Michigan lake area. The goal is to assess the use of the public available Landsat images on shallow water depth inversion. Firstly, ICESAT elevation data were used to determine the absolute water surface elevation. Airborne bathymetry Lidar data provide systematic measure of water bottom elevation. Subtracting water bottom elevation from water surface elevation will result in water depth. Water depth is associated with reflectance recorded as DN value in Landsat images. Water depth inversion was tested on ANN models, SVM models with four different kernel functions and regression tree model that exploit the correlation between water depth and image band ratios. The result showed that the RMSE (root-mean-square error) of all models are smaller than 1.5 meters and the R2 of them are greater than 0.81. The conclusion is Landsat images can be used to measure water depth in shallow area of the lakes. Potentially, water volume change of the Great Lakes can be monitored by using the procedure explored in this research

Deep learning in remote sensing: a review

Standing at the paradigm shift towards data-intensive science, machine learning techniques are becoming increasingly important. In particular, as a major breakthrough in the field, deep learning has proven as an extremely powerful tool in many fields. Shall we embrace deep learning as the key to all? Or, should we resist a 'black-box' solution? There are controversial opinions in the remote sensing community. In this article, we analyze the challenges of using deep learning for remote sensing data analysis, review the recent advances, and provide resources to make deep learning in remote sensing ridiculously simple to start with. More importantly, we advocate remote sensing scientists to bring their expertise into deep learning, and use it as an implicit general model to tackle unprecedented large-scale influential challenges, such as climate change and urbanization.Comment: Accepted for publication IEEE Geoscience and Remote Sensing Magazin