Sinovitis villonodular pigmentada difusa: Revisión de 13 casos

Se hace un estudio retrospectivo de trece pacientes con Sinovitis Villonodular pigmentada, seis localizadas en la rodilla, dos en la muñeca y pie, y uno en tobillo, cadera y codo respectivamente. En cinco de los casos existía una afectación del hueso. Se hace una revisión bibliográfica sobre la etiopatogenia, radiología, métodos diagnósticos y tratamientoA retrospective study of thirteen patients with pigmented villonodular synovitis was made. Six cases were localized in the knee, two in the wrist and feet, and one in ankle, hip and elbow. Five case showed bone invasion, the pathogenesis, radiographical appearance, diagnosis and treatment are discussed

Origin and Control Strategies of Biofilms in the Cultural Heritage

Biodeterioration is defined as the undesirable change in the properties of materials caused by the activity of biological agents. This process is complex and involves alterations in the physicochemical and mechanical properties by the action of organisms and depends on the microorganisms involved, type of substrate, and environmental conditions. The biodeterioration of cultural heritage is the physical or chemical damage caused by microorganisms on objects, monuments, or buildings that belong to the cultural heritage. Among the main materials that can be affected are: stone, metal, ceramic, polymers, and other materials. Among the main undesirable effects to these materials are: discoloration, dissolution, rupture, and efflorescence among others. Biofilms represent the usual form of growth of bacteria and consist of communities of microorganisms that grow attached to an inert surface or a living tissue, surrounded by an extracellular matrix that they themselves synthesize. The importance of biodeterioration by biofilms is mainly related to changes in pH values, ionic concentrations, oxide-reduction reactions in the biofilm thickness, and in the interface with the substrate and enzymatic degradation. This chapter presents evidence of the participation of biofilms and associated mechanisms in biodeterioration as well as the main prevention and control strategies

Albayzín-2014 evaluation: audio segmentation and classification in broadcast news domains

The electronic version of this article is the complete one and can be found online at: http://dx.doi.org/10.1186/s13636-015-0076-3Audio segmentation is important as a pre-processing task to improve the performance of many speech technology tasks and, therefore, it has an undoubted research interest. This paper describes the database, the metric, the systems and the results for the Albayzín-2014 audio segmentation campaign. In contrast to previous evaluations where the task was the segmentation of non-overlapping classes, Albayzín-2014 evaluation proposes the delimitation of the presence of speech, music and/or noise that can be found simultaneously. The database used in the evaluation was created by fusing different media and noises in order to increase the difficulty of the task. Seven segmentation systems from four different research groups were evaluated and combined. Their experimental results were analyzed and compared with the aim of providing a benchmark and showing up the promising directions in this field.This work has been partially funded by the Spanish Government and the European Union (FEDER) under the project TIN2011-28169-C05-02 and supported by the European Regional Development Fund and the Spanish Government (‘SpeechTech4All Project’ TEC2012-38939-C03

Probing the Nuclear and Circumnuclear Activity of NGC1365 in the Infrared

We present new far-infrared (70-500micron) Herschel PACS and SPIRE imaging observations as well as new mid-IR Gemini/T-ReCS imaging (8.7 and 18.3micron) and spectroscopy of the inner Lindblad resonance (ILR) region (R<2.5kpc) of the spiral galaxy NGC1365. We complemented these observations with archival Spitzer imaging and spectral mapping observations. The ILR region of NGC1365 contains a Seyfert 1.5 nucleus and a ring of star formation with an approximate diameter of 2kpc. The strong star formation activity in the ring is resolved by the Herschel/PACS imaging data, as well as by the Spitzer 24micron continuum emission, [NeII]12.81micron line emission, and 6.2 and 11.3micron PAH emission. The AGN is the brightest source in the central regions up to lambda~24micron, but it becomes increasingly fainter in the far-infrared when compared to the emission originating in the infrared clusters (or groups of them) located in the ring. We modeled the AGN unresolved infrared emission with the CLUMPY torus models and estimated that the AGN contributes only to a small fraction (~5%) of the infrared emission produced in the inner ~5kpc. We fitted the non-AGN 24-500micron spectral energy distribution of the ILR region and found that the dust temperatures and mass are similar to those of other nuclear and circumnuclear starburst regions. Finally we showed that within the ILR region of NGC1365 most of the on-going star formation activity is taking place in dusty regions as probed by the 24micron emission.Comment: Accepted for publication in MNRA

The starburst-AGN connection in the merger galaxy Mrk 938: an infrared and X-ray view

Mrk938 is a luminous infrared galaxy in the local Universe believed to be the remnant of a galaxy merger. It shows a Seyfert 2 nucleus and intense star formation according to optical spectroscopic observations. We have studied this galaxy using new Herschel far-IR imaging data in addition to archival X-ray, UV, optical, near-IR and mid-IR data. Mid- and far-IR data are crucial to characterise the starburst contribution, allowing us to shed new light on its nature and to study the coexistence of AGN and starburst activity in the local Universe. The decomposition of the mid-IR Spitzer spectrum shows that the AGN bolometric contribution to the mid-IR and total infrared luminosity is small (Lbol(AGN)/LIR~0.02), which agrees with previous estimations. We have characterised the physical nature of its strong infrared emission and constrained it to a relatively compact emitting region of <2kpc. It is in this obscured region where most of the current star formation activity is taking place as expected for LIRGs. We have used Herschel imaging data for the first time to constrain the cold dust emission with unprecedented accuracy. We have fitted the integrated far-IR spectral energy distribution and derived the properties of the dust, obtaining a dust mass of 3x10^7Msun. The far-IR is dominated by emission at 35K, consistent with dust heated by the on-going star formation activity.Comment: 12 pages, 6 figures, 4 tables, accepted for publication in MNRA

Biomaterials from beer manufacture waste for bone growth scaffolds

Agricultural wastes are a source of renewable raw materials (RRM), with structures that can be tailored for the use envisaged. Here, they have proved to be good replacement candidates for use as biomaterials for the growth of osteoblasts in bone replacement therapies. Their preparation is more cost effective than that of materials presently in use with the added bonus of converting a low-cost waste into a value-added product. Due to their origin these solids are ecomaterials. In this study, several techniques, including X-ray diffraction (XRD), chemical analysis, mercury intrusion porosimetry (MIP), scanning electron microscopy (SEM), and bioassays, were used to compare the biocompatibility and cell growth of scaffolds produced from beer bagasse, a waste material from beer production, with a control sample used in bone and dental regenerative processes

Clonal human fetal ventral mesencephalic dopaminergic neuron precursors for cell therapy research

A major challenge for further development of drug screening procedures, cell replacement therapies and developmental studies is the identification of expandable human stem cells able to generate the cell types needed. We have previously reported the generation of an immortalized polyclonal neural stem cell (NSC) line derived from the human fetal ventral mesencephalon (hVM1). This line has been biochemically, genetically, immunocytochemically and electrophysiologically characterized to document its usefulness as a model system for the generation of A9 dopaminergic neurons (DAn). Long-term in vivo transplantation studies in parkinsonian rats showed that the grafts do not mature evenly. We reasoned that diverse clones in the hVM1 line might have different abilities to differentiate. In the present study, we have analyzed 9 hVM1 clones selected on the basis of their TH generation potential and, based on the number of v-myc copies, v-myc down-regulation after in vitro differentiation, in vivo cell cycle exit, TH+ neuron generation and expression of a neuronal mature marker (hNSE), we selected two clones for further in vivo PD cell replacement studies. The conclusion is that homogeneity and clonality of characterized NSCs allow transplantation of cells with controlled properties, which should help in the design of long-term in vivo experimentsThis work was supported by grants from the Spanish Ministry of Economy and Competitiveness (formerly Science and Innovation; PLE2009-0101, SAF2010-17167), Comunidad Autónoma Madrid (S2011-BMD-2336), Instituto Salud Carlos III (RETICS TerCel, RD06/0010/0009) and European Union (Excell, NMP4-SL-2008-214706). This work was also supported by an institutional grant from Foundation Ramón Areces to the Center of Molecular Biology Severo Ocho