7 research outputs found

    Process evaluation of the sedation and weaning in children (SANDWICH) multicentre stepped wedge, cluster randomised controlled trial

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    Data from interviews and focus groups undertaken with clinical staff working in United Kingdom (UK) paediatric intensive care units (PICUs), with a role in weaning children from mechanical ventilation. Data were collected between July 2019 and March 2020. Participants included nurses (bedside, senior clinical management, and advanced nurse practitioners), medical staff (medical trainees and consultant intensivists), allied health professionals (physiotherapists, pharmacists and nursing assistants) and members of the hospital/unit research teams. Data address their understanding and experience of the SANDWICH trial. Note this data forms the basis of the following published paper: "Delivery of a novel intervention to facilitate liberation from mechanical ventilation in paediatric intensive care: a process evaluation" (2023). Owing to the sensitive nature of the data created during this study, data is available via restricted access. Data is embargoed until 1 November 2025. Thereafter, it is available via restricted access conditions. To request access after the embargo period, please contact RDM Team at Queen’s University Belfast Email: [email protected]

    DIPLOMATIC study documents

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    This archive comprises study documents including work packages 1 to 8, some of the materials include the following: - study protocol (an over-arching very detailed description of the experiment); - consent forms; - educational materials relating to ultrasound scanning and so on. ## Access ## Requests for a copy of the data are welcome. The data are held in the DataVault, which is directly accessible only to University of Edinburgh nominated users. To request a copy, please contact Lorraine Adamson.DIPLOMATIC is a clinical trial, a multidisciplinary international collaboration investigating interventions in pre-term birth and still-term birth in low and middle income countries. (DIPLOMATIC: using eviDence, Implementation science, and a clinical trial PLatform to Optimise MATernal and newborn health in low Income Countries)

    Immunosuppressive therapy for kidney transplantation in adults: a systematic review and economic model.

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    End-stage renal disease is a long-term irreversible decline in kidney function requiring renal replacement therapy: kidney transplantation, haemodialysis or peritoneal dialysis. The preferred option is kidney transplantation, followed by immunosuppressive therapy (induction and maintenance therapy) to reduce the risk of kidney rejection and prolong graft survival.This article is freely available. Click on the 'Additional Link' above to access the full-text
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