10 research outputs found
Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic
- Author
- 14 | COVIDSurg COllabOratIVe Tzovaras G. (General University Hospital of Larissa)
- Aawsaj Y.
- Abad Gurumeta A.
- Abad-Motos A.
- Abate E.
- Abbott D.
- Abdalla M.
- Abdeldayem H.
- Abdelkader Salama I.
- Abdelkarim M.
- Abdur-Rahman L.
- Abel M. K.
- Aboelkassem Ibrahim A.
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- Abubakar A.
- Acebes García F.
- Achalandabaso Boira M. Sales Mallafré R. (Hospital Universitari de Tarragona Joan XXIII)
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- Adamina M.
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- Adeyeye A.
- Adiamah A.
- Afonso J.
- Agapov M.
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- Aljiffry M.
- Alma Mater Studiorum University of Bologna)
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- Almeida J. I.
- Almeida-Reis R.
- Alnumani T. (King Fahad 16 | COVIDSurg COllabOratIVe General Hospital)
- Alobeed O.
- Alonso de la Fuente N. Jimenez Toscano M. (Hospital del Mar)
- Alonso Poza A.
- Alonso- Lamberti L.
- Alqannas M.
- Alselaim N. (King Saud Bin Abdulaziz University for Health Sciences
- Alshammari S.
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- Aou Sassari)
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- Argentina: Alurralde C.
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- Campus Benjamin Franklin)
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- Castellammare di Stabia)
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- Clifford R.
- Clinical Centre of Serbia)
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- Coughlin P.
- COVIDSurg COllabOratIVe | 15 Violante T. (IRCCS Azienda Ospedaliero – Universitaria di Bologna
- Cozza V.
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- Crichton A.
- Cristian D.
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- Day A. (East Surrey Hospital)
- De Andres Olabarria U.
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- Department of Biomedical Sciences
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- EPE)
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- General Surgery Department)
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- Government Medical College). Ireland: Aremu M.
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- Lomonosov Moscow State University). Saudi Arabia: Alshahrani M.
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- Ministry of National Guard
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- TU Dresden)
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- Universiti Sains Malaysia)
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- Publication venue
- 'Wiley'
- Publication date
- 01/01/2020
- Field of study
This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic
Concurrent functional processes
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- Publication date
- 01/01/1993
- Field of study
Eden - The Paradise of Functional Concurrent Programming
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- Field of study
s of all (predefined and user-defined) processes interacting via communication on channels. 1 Eden in a nutshell Haskell forms the computation language of Eden. This is extended by a coordination model that introduces processes in a functional style, embodying constructs which allow for the definition and creation of processes, communication and synchronization, and the specification of interconnections between processes. Eden distinguishes between process abstractions, which specify process behaviour in a purely functional way, and process instantiations in which process abstractions are supplied with input values in order to create new processes. A process abstraction defines a general parameterized process scheme. It specifies a process which maps (streams of) input values in 1 , : : : , inm to (streams of) output values out 1 ,<F
Towards Improving Skeletons in Eden ∗
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Permission to make digital or hard copies of portions of this work for personal or classroom use is granted provided that the copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. To copy otherwise requires prior specific permission by the publisher mentioned above
Fuzzy-Timed Automata
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2010
- Field of study
Ethnobotany of Mexican and northern Central American cycads (Zamiaceae)
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- A González-Coloma
- Andrew P. Vovides
- Angélica Cibrián-Jaramillo
- AP Vovides
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- AP Vovides
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- AP Vovides
- AU Valdez
- Aurelia Vite-Reyes
- B Dehgan
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- BD Smith
- CE Smith
- CJ Chamberlain
- D Graham
- EL Yáñez
- F Hernandez
- G Bachelard
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- GJ Martin
- H Chemin Bassler
- H Cortés
- HG Smith
- HG Wilkes
- HL Mickleburgh
- I Ruiz-Mallén
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- J Mondragón-Pichardo
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- JB Alcorn
- JC Steele
- JH Kempton
- JJ Bradley
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- JW Thieret
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- KJ Norstog
- L Newsom
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- M Bonta
- M Bonta
- M Calonje
- M Smith
- M Whiting
- MA Bonta
- Mark Bonta
- María Teresa Pulido-Silva
- ME Galaviz de Capdevielle
- MG Whiting
- MT Pulido
- MT Pulido
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- P Radha
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- R Dickau
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- SR Simms
- Teresa Diego-Vargas
- TS Grove
- VA Reko
- VM Patiño
- VM Patiño
- W Beck
- W Reyes
- W Tang
- Y Matsuoka
- Y Mayett Moreno
- YF Tuan
- Publication venue
- 'Springer Science and Business Media LLC'
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- Field of study
The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study
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- Herrod P
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- Impellizzeri H
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- Papadopoulos V
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- Pinto J
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- Pla‐Marti V
- Pockney P
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- Ângelo M
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- Çelebi F
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- Ćoza I
- Ławnicka A
- Žatecký J
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2022
- Field of study
AimThe SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery.MethodsThis was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin.ResultsOverall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P ConclusionOne in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease
Delaying surgery for patients with a previous SARS-CoV-2 infection
- Author
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- A Abdelmajeed
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- A Abdelsamed
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- U Akgor
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- W Oosterlinck
- W Raby-Smith
- W Smolka
- W Van Houdt
- W Yang
- Willemijn van der Plas
- Wong Mpk
- X De Sousa
- X Morales
- X S Tan
- Y Aawsaj
- Y Al-Tamimi
- Y Arkha
- Y Ayasra
- Y Bashir
- Y El Bouazizi
- Y Fayed
- Y H Lam
- Y Kanemitsu
- Y Kara
- Y Kirmizi
- Y Levy-Zauberman
- Y Litvina
- Y Perez
- Y T Liew
- Y Tanase
- Y Viswanath
- Y Ying
- Z Al-Ishaq
- Z Aldayri
- Z Aliyeva
- Z Bayhan
- Z Chia
- Z Dzamic
- Z H Belkhadir
- Z Inic
- Z Jawad
- Z Jezdic
- Z Katusic
- Z Krivokapic
- Z Lakkis
- Z Li
- Z M Barrett-Brown
- Z Mahasin
- Z Seymour
- Z Vilendecic
- Z Zakaria
- Á De la Hoz Rodríguez
- Á Fernández Camuñas
- É Ryan
- Ž Grubač
- А Камалов
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2020
- Field of study
Not availabl
Elective Cancer Surgery in COVID-19–Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study
- Author
- Aawsaj Y
- Abad Gurumeta A
- Abad-Motos A
- Abate E
- Abatini C
- Abbadessa F
- Abbas AM
- Abbassi-Ghadi N
- Abbott D
- Abbott T
- Abbott Tom EF
- Abd Elazeem HAS
- Abdalla M
- Abdallah M
- Abdel Al S
- Abdel Jalil R
- Abdeldayem H
- Abdelkader Salama I
- Abdelkarem MM
- Abdelkarim M
- Abdelmajeed A
- Abdelrahman A
- Abdelrahman S
- Abdelsamed A
- Abdou M
- Abdulkareem A
- Abdulwahed E
- Abdur-Rahman L
- Abel MK
- Abellán M
- Aboelkassem Ibrahim A
- Abosamak NE
- Abou Chaar MK
- Abou Chaar Mohammad K.
- Abou-Khalil J
- Abouassi A
- Aboulkassem H
- Abreu da Silva A
- Abu Za’nouneh FJ
- Abu J
- Abu-Nayla I
- Abubakar A
- Abukhalaf Sadi
- Acebes García F
- Achalandabaso Boira M
- Acher A
- Acrich E
- Adamina M
- Adamina Michel
- Adamoli L
- Addae-Boateng E
- Ademuyiwa Adesoji O
- Aderombi A
- Adeyeye A
- Adiamah A
- Adishesh M
- Agapov M
- Agarwal Arnav
- Aggarwal A
- Aghayeva A
- Agilinko J
- Agnes A
- Agostini C
- Agoston P
- Agrawal A
- Agresta F
- Aguado H
- Aguilar Gonzalez M
- Aguzzoli L
- Ahad S
- Ahmadi N
- Ahmeidat A
- Ahn JH
- Aiken T
- Aimé A
- Ajlan A
- Akalin M
- Akaydin E
- Akeel N
- Akgor U
- Akhtar MA
- Akhter Rahman MM
- Akilli H
- Akin E
- Akkour K
- Akkulak Murat
- Akmenkalne L
- Al Abdallah M
- Al Awwad S
- Al Habes H
- Al Maadany FS
- Al Raddadi R
- AL Sayed M
- Al-Habib A
- Al-Habsi R
- Al-Ishaq Z
- Al-Khayal K
- Al-Masri M
- Al-Mohammad A
- Al-mukhtar A
- Al-Najjar H
- Al-omishy H
- Al-Sarireh B
- Al-Tamimi Y
- Alaa S
- AlAamer O
- Aladeojebi A
- Alakaloko Felix
- Alam F
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- Alameer Ehab
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- Alanbuki A
- Alatar A
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- Alazawi D
- Albertsmeier M
- Albertsmeiers Markus
- Albi Martin B
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- Aldecoa Ansorregui I
- Alderson Derek
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- Alfieri S
- Alghamdi M
- Alhalal H
- Alhamed A
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- Alharthi R
- Alhassan B
- Alhassan N
- Alhefdhi A
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- Ali AK
- Ali M
- Ali S
- Aliyeva Z
- Aljanadi F
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- Alkadeeki GZ
- Alkarak S
- Allemand C
- Allison J
- Almalik O
- Almasri M
- Almeciga A
- Almeida A
- Almeida AC
- Almeida JI
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- Alsaif A
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- Alser Osaid
- Alshaar Muhammad
- Alshahrani M
- Alshammari S
- Alshareea E
- Alsharif F
- Alshaygy I
- Alshryda Sattar
- Alsobhi S
- Althobaiti W
- Altintoprak F
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- Alvarez E
- Alvarez MR
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- Anania G
- Anastasi A
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- Antonopoulou MI
- Anula R
- Anwar S
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- Aprile A
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- Arikan AE
- Arkadopoulos N
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- Armao T
- Armatura G
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- Artigues E
- Arulanantham A
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- Asqalan A
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- Assalaarachchi H
- Asti E
- Astreidis I
- Ataíde Gomes Gustavo Mendonça
- Athanasakis E
- Athanasiou A
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- Augestad Knut Magne
- Avci EK
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- Badellino E
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- Baiao JM
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- Balakrishnan A
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- on behalf of the COVIDSurg Collaborative
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- Vieira Paiva Lopes AC
- Vieira A
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- Wensley F
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- Whitehall E
- Whitmore H
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- Wilkin Richard JW
- Wilkins A
- Wilkins Alex
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- Williams MA
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- Wimmer A
- Winnand P
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- Wullschleger M
- Wustrack R
- Xenaki S
- Xu MJ
- Xyda SE
- Xynos E
- Yahaya AS
- Yang W
- Yassin N
- Ye G
- Yesantharao P
- Yetkin G
- Yeşilyurt D
- Yiallourou A
- Yıldırım A
- Yildiz A
- Ying Y
- Yip V
- Yordanov S
- Young R
- Yousof EA
- Youssef A
- Youssef M
- Yurttas C
- Yánez C
- Yüksel E
- Zacharoulis D
- Zafar SN
- Zakai D
- Zakaria AD
- Zakaria R
- Zakaria Z
- Zambelli MF
- Zambon M
- Zamora L
- Zamvar V
- Zani S
- Zanotti S
- Zanus G
- Zapardiel I
- Zarabini AG
- Zegarac M
- Zelić M
- Zeller N
- Zengin AK
- Zerbib P
- Zervas K
- Zese M
- Zhang H
- Zivanovic M
- Zivkovic M
- Zizzo M
- Zografos C
- Zonta S
- Zorrilla Ortúzar J
- Zourntou S
- Zouzoulas D
- Zubaidi A
- Zullo A
- Ângelo M
- Älgå A
- Çapoğlu R
- Çelebi F
- Çolak E
- Öfner D
- Öhlberger L
- Öğücü H
- Überrück L
- Ćoza I
- Šimko K
- Šćepanović V
- Žatecký J
- Камалов А
- Publication venue
- American Society of Clinical Oncology
- Publication date
- 01/01/2021
- Field of study
Recommended from our members
Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study an international prospective cohort study
- Author
- Ababneh Hazim
- Abad-Motos Ane
- Abbas Ferial Mohamed Ali
- Abbo Olivier
- Abbott Tom
- Abbott Tom
- Abdelkabir Mohammed
- Abdelkhalek Mohamed
- Abdoun Meriem
- Abdur-Rahman Lukman
- Abdur-Rahman Lukman
- Abebe Metasebia
- Aboazamazem Hajir
- Abou Chaar Mohamad K.
- Abou Chaar Mohamad K.
- Abouelnagah Galal
- Abozied Hesham
- Abu Salhiyeh Ala A.
- Abu-Ismail Luai
- Abu-Mehsen Marah
- Abuawad Carla
- Abukhalaf Sadi A.
- Abuleil Amro
- Ackermann Travis
- Acquah Daniel Kwesi
- Adam Mohammed Elmujtba Adam Essa
- Adamina Michel
- Adamina Michel
- Ademuyiwa Adesoji
- Adesanya Opeoluwa
- Adisa Adewale
- Adisa Adewale
- Afolabi Akinwale
- Agarwal Arnav
- Agarwal Gaurav
- Agarwal Ketan
- Agastra Ervis
- Agastra Ervis
- Agbadebo Mouhamed
- Agbonrofo Peter
- Aguilera-Arevalo Maria-Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahmad Amer
- Ahmad Siddique
- Ahmadi Navid
- Ahmed Waheed-Ul-Rahman
- Aigner Felix
- Aiken Taylor
- Akhavizadegan Hamed
- Akhbari Melika
- Akililu Yemisirach Bizuneh
- Akinmade Akinola
- Al Ameer Ahmed
- Al Ameer Ahmed
- Al Amri Abdulrahman
- Al Balushi Zainab
- Al Islam Ben Jouira Rayet
- Al Maadany Faraj
- Al-Manaseer Balqees Mahmoud
- Al-Naggar Hamza
- Al-Naggar Hamza
- Al-Raimi Ibrahim
- Al-Sabbagh Yusra
- Al-Shehari Mohammed
- Aladawi Omar
- Alajalen Amer
- Alalawi Yousef
- AlAmeer Ehab
- Alameer Ehab
- Alansari Arowa Hassan Abdulrahman
- Alawami Mohammed
- Alawneh Yazan
- Alayan Mohammed
- Albared Sara Maa
- Albertsmeier Markus
- Albertsmeier Markus
- Alderazi Amer
- Aldlyami Ehab
- Aldressi Wafa
- Alecci Anna
- Alexander Philip
- AlFakhri Abdullah
- Alharthi Mohammed
- Alhassoun Turki
- Alhefdhi Amal
- Alkadeeki Ghadah
- Alkaseek Akram
- Alkhatib Ahmad
- Allemand Carola
- Almabayev Ydyrys
- Almeida-Reis Rui
- Almiqlash Bushray
- Almoguera Jorge
- Almugaddami Ayman
- Almulhim Abddulrahman Saleh
- Alnachoukati Omar
- Alnahr Hareth
- Alonso Jesús Aarón Martínez
- Alonso Manuel Diez
- Alonso Nestor Fabian Pedraza
- Alqudah Majdi Ali
- Alrayes Bourhan
- Alsaadi Hayder
- Alsaadi Hayder
- Alser Osaid
- Alshaar Muhammad
- Alshahrani Mushabab
- Alshareef Khayriyah
- Alshehri Ameen
- Alshryda Sattar
- Alshryda Sattar
- Alsibai Sareyah
- Alsunna Zaid
- Altaf Humera Naz
- Althumairi Azah
- Althumairi Azah
- Althumairi Azah
- Alvarado Carlos Eduardo Otiniano
- Alyami Mohammad
- Alzahrani Abdulrahman
- Alzaidi Turki M.
- Alzate Juan Pablo
- Alzerwi Nasser
- Amisi Nicolas
- Amnaina Mohamed
- Amor María Sol Crespi
- André Benoît
- Angeles Martina Aida
- Anwer Mariyah
- Anyanwu Lofty-John
- Aouabed Nesrine
- Aqeelah Ahmed
- Aqil Sabra
- Arancibia José Alfredo Calderón
- Arango Maria Clara Mendoza
- Arbane Gill
- Argus Leah
- Arias Claudia
- Arnalsteen Laurent
- Arnaud Alexis P.
- Arnaud Alexis P.
- Asif Muhammad
- Assefa Melatework
- Atnafu Bahru
- Aulerio Giuliana D.
- Aurora
- Awad Selmy
- Ayasra Faris
- Ayasra Faris
- Ayoub Abdu
- Ayub Bushra
- Ayub Khurram
- Azevedo José
- Azevedo José
- Azevedo Pedro
- Aziz Aliya
- Azzam Ahmed Y.
- Bacalbasa Nicolae
- Badareesh L.
- Badenes Rafael
- Badiani Sarit
- Baig Mariam
- Bains Lovenish
- Baiocchi Glauco
- Baiocchi Glauco
- Baiocchi Glauco
- Bajaj Ankur
- Balanta-Melo Julián
- Balasubramanya Supriya
- Bali Oussama
- Baliarsing Lipika
- Ball Alasdair
- Ballouhey Quentin
- Ban Vin Shen
- Bankhead-Kendall Brittany
- Bankhead-Kendall Brittany
- Barillas Sabrina
- Barker John
- Barros Aldo Vieira
- Basnayake Oshan
- Bastet Joaquin
- Basu Somprakas
- Bateman Antony
- Bath Michael
- Batista Sylvia
- Bauset Juan Carlos Catalá
- Bayo Heura Llaquet
- Baía Catarina
- Behzadi Abdollah
- Bekele Kebebe
- Bele Uros
- Bele Uros
- Bellver Pedro Palazon
- Ben Amer Anass
- Benallel Nassim
- Benson Ruth
- Berber Norberto
- Bergeat Damien
- Bergkvist David Julià
- Bernal-Sprekelsen Juan Carlos
- Berndtson Allison
- Bertrand Marta
- Bescós Coro
- Bezabih Yoseph Solomon
- Bhanderi Shivam
- Bhangu Aneel
- Bhangu Aneel
- Bhat Dhananjaya
- Bhatti Abu Bakar Hafeez
- Bhende Vishal
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- Sinnerton Robert
- Sisay Silamlak
- Slavchev Mihail
- Slavchev Mihail
- Slim Karem
- Slullitel Pablo
- Smart Neil
- Soares Ana
- Sodhai Vivek
- Sole Oriol Martin
- Solé Misericòrdia Jordà
- Soni Rajesh
- Sonksen Julian
- Sooriyabandara Charitha
- Soria Vanesa Garcia
- Soto-Darias Iván
- Soualili Zineddine
- Spelsberg Fritz
- Squiers John
- Srishankar Selvaratnam
- St-Germain Pascal
- Stadler Josef
- Stang María Verona
- Stavridis Sotir
- Stavrou Gregor A.
- Steinkamp Pieter
- Steinkamp Pieter
- Stephens Matthew
- Stevens Sean
- Stewart Grant D.
- Stewart Grant D.
- Stijns Jasper
- Stoleriu Mircea Gabriel
- Suarez Marcelo Moreno
- Subbian Anbukkani
- Suliaman Taha
- Sultan Rizwan
- Sultana Asma
- Sumadi Adnan
- Sund Malin
- Surendran Arthika
- Suroy Atul
- Szakmany Tamas
- Sánchez Alberto Cabañero
- Sánchez Iran Irani Durán
- Sánchez-Cabús Santiago
- Tabiri Stephen
- Taboada María Victoria
- Tachella Sofia
- Tadesse Anteneh
- Talat Nabila
- Talib Ahmar Iftikhar
- Talwar Rishi
- Tamoos Khalil
- Tampaki Ekaterini Christina
- Tan Lorwai
- Tariq Aiman
- Tariq Muhammad
- Tarrado Xavier
- Taylor Elliott H.
- Teague Rebecca
- Teasdale Ella
- Tefera Teshome
- Tejero-Pintor Francisco J.
- Tendeng Jacques
- Teo Nan Zun
- Teresa Gavaldà Pellicé M.
- Testelin Sylvie
- Thakar Sumit
- Thereska Dariel
- Thereska Dariel
- Thies Cristina Ojeda
- Thyavihally Yuvaraja
- Tirapegui Sebastian
- Todorovic Lazar
- Tojal André
- Tolani Musliu Adetola
- Toma Elena Adelina
- Tornini Alejandra
- Toro Carlos Andres Marulanda
- Torres Martha Luz
- Toscano Marta Jimenez
- Totty Joshua
- Townend Philip
- Traeger Luke
- Traverso Rogelio
- Tripathi Manjul
- Trout Isobel M.
- Trujillo Lina María
- Tsegaye Bereket
- Tsoulfas Georgios
- Tudela Kiara
- Turinawe Gaston
- Turner Paul
- Turrado-Rodriguez Victor
- Uffelmann Constanza
- Ugarte-Sierra Bakarne
- Usang Usang
- Vaccaro Carlos
- Vagni Roberto
- Vaishnav Dhaivat
- Valcarcel Cristina Rey
- Valdez Pedro
- Valerio Ana Clara
- Vallam Karthik Chandra
- Vallve-Bernal Marc
- van Ramshorst Gabrielle
- van Ramshorst Gabrielle
- Vargas Lara
- Varghese Chris
- Varghese Chris
- Varghese Chris
- Varghese Chris
- Vartanian Jose Guilherme
- Vaughan-Shaw Peter
- Vayoth Sudheer Othiyil
- Vaysburg Dennis
- Vaysse Charlotte
- Velasco Jorge Caño
- Velasquez Enrique Jose Ruiz
- Venkatappa Sunil Kumar
- Venn Mary L.
- Verhaeghe Romain
- Verhaeghe Romain
- Vidal Rafael Perez
- Vidya Raghavan
- Vijayakumar Vijayakumar M.
- Villanueva Julio
- Vimalakanthan Thanusan
- Vita Diana Crego
- Vivancos Patricia Caja
- Viveiros Octavio
- Vives Inmaculada
- Vives Josep Maria Muñoz
- Vo Uyen Giao
- von Pusch Silke
- Vrapi Enxhi
- Vázquez Irene Ortega
- Wafi Omar
- Wagner Arthur
- Waissbluth Sofia
- Waqar Shahzad Hussain
- Watson David
- Watson Eleanor
- Watters David
- Weeraddana Prabuth Dulanjan
- Wells Cameron
- Welter Stefan
- Wettstein Dániel
- Wickramasinghe Dakshitha
- Wickramasinghe Dakshitha
- Wiegering Armin
- Wijeysundera Duminda
- Williams Emmanuel
- Williams Omolara
- Williams Omolara
- Wilson Michael
- Wolf Sebastian
- Wolfer Susanne
- Wong Enoch
- Wright Deborah
- Wright Deborah
- Wright Naomi
- Wuraola Funmilola
- Wuraola Funmilola
- Xaviour Okedi Francis
- Xu William
- Yadev I.
- Yagoub Ghozlan
- Yaqoob Eesha
- Yaqoob Hassan Nawaz
- Yasin Seid Mohammed
- Yazbek Guilherme
- Yebes Alvaro
- Yeung Justin
- Yip Sebastian Shu
- Youssef Mina
- Zabaleta Jon
- Zahid Imdad Ahmad
- Zanoni Gerardo
- Zapardiel Ignacio
- Zapata Carlos Shiraishi
- Zarnescu Narcis Octavian
- Zarour Ahmad
- Zarour Ahmad
- Zarour Ahmad
- Zarratea Celeste Soledad
- Zegarra Sergio
- Zequi Stenio C.
- Zezular Damaris Idara Anabel
- Zhou Xuanyu
- Zhussupov Baurzhan
- Zijaj Lorena
- Zimmelman Natalie
- Zmora Oded
- Zmora Oded
- Zohra Belabbes Fatima
- Publication venue
- HAL CCSD
- Publication date
- 01/11/2021
- Field of study
We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which patients did not leave their house or receive visitors from outside their household. The primary outcome was postoperative pulmonary complications, adjusted in multivariable models for measured confounders. Pre-defined sub-group analyses were performed for the primary outcome. A total of 96,454 patients from 114 countries were included and overall, 26,948 (27.9%) patients isolated before surgery. Postoperative pulmonary complications were recorded in 1947 (2.0%) patients of which 227 (11.7%) were associated with SARS-CoV-2 infection. Patients who isolated pre-operatively were older, had more respiratory comorbidities and were more commonly from areas of high SARS-CoV-2 incidence and high-income countries. Although the overall rates of postoperative pulmonary complications were similar in those that isolated and those that did not (2.1% vs 2.0%, respectively), isolation was associated with higher rates of postoperative pulmonary complications after adjustment (adjusted OR 1.20, 95%CI 1.05–1.36, p = 0.005). Sensitivity analyses revealed no further differences when patients were categorised by: pre-operative testing; use of COVID-19-free pathways; or community SARS-CoV-2 prevalence. The rate of postoperative pulmonary complications increased with periods of isolation longer than 3 days, with an OR (95%CI) at 4–7 days or ≥ 8 days of 1.25 (1.04–1.48), p = 0.015 and 1.31 (1.11–1.55), p = 0.001, respectively. Isolation before elective surgery might be associated with a small but clinically important increased risk of postoperative pulmonary complications. Longer periods of isolation showed no reduction in the risk of postoperative pulmonary complications. These findings have significant implications for global provision of elective surgical care. We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which patients did not leave their house or receive visitors from outside their household. The primary outcome was postoperative pulmonary complications, adjusted in multivariable models for measured confounders. Pre-defined sub-group analyses were performed for the primary outcome. A total of 96,454 patients from 114 countries were included and overall, 26,948 (27.9%) patients isolated before surgery. Postoperative pulmonary complications were recorded in 1947 (2.0%) patients of which 227 (11.7%) were associated with SARS-CoV-2 infection. Patients who isolated pre-operatively were older, had more respiratory comorbidities and were more commonly from areas of high SARS-CoV-2 incidence and high-income countries. Although the overall rates of postoperative pulmonary complications were similar in those that isolated and those that did not (2.1% vs 2.0%, respectively), isolation was associated with higher rates of postoperative pulmonary complications after adjustment (adjusted OR 1.20, 95%CI 1.05–1.36, p = 0.005). Sensitivity analyses revealed no further differences when patients were categorised by: pre-operative testing; use of COVID-19-free pathways; or community SARS-CoV-2 prevalence. The rate of postoperative pulmonary complications increased with periods of isolation longer than 3 days, with an OR (95%CI) at 4–7 days or ≥ 8 days of 1.25 (1.04–1.48), p = 0.015 and 1.31 (1.11–1.55), p = 0.001, respectively. Isolation before elective surgery might be associated with a small but clinically important increased risk of postoperative pulmonary complications. Longer periods of isolation showed no reduction in the risk of postoperative pulmonary complications. These findings have significant implications for global provision of elective surgical care