285 research outputs found
A dysflagellar mutant of Leishmania (Viannia) braziliensis isolated from a cutaneous leishmaniasis patient
- Author
- Publication venue
- BioMed Central
- Publication date
- 01/01/2012
- Field of study
<p>Abstract</p> <p>Background</p> <p>Parasites of the <it>Leishmania </it>genus alternate between the flagellated extracellular promastigote stage and intracellular amastigotes. Here we report the characterization of a <it>Leishmania </it>isolate, obtained from a cutaneous leishmaniasis patient, which presents peculiar morphological features.</p> <p>Methods</p> <p>The parasite was cultured <it>in vitro </it>and characterized morphologically using optical and electron microscopy. Identification was performed based on monoclonal antibodies and internal ribosomal spacer typing. <it>In vitro </it>macrophage cultures, murine experimental models and sand fly infections were used to evaluate infectivity <it>in vitro </it>and <it>in vivo</it>.</p> <p>Results</p> <p>The isolate was identified as <it>Leishmania </it>(<it>Viannia</it>) <it>braziliensis</it>. In the atypical promastigotes grown in culture, a short flagellum surrounded or interrupted by a protuberance of disorganized material was observed. A normal axoneme was present close to the basal body but without elongation much further outside the flagellar pocket. A disorganized swelling at the precocious end of the axoneme coincided with the lack of a paraflagellar rod structure. The isolate was able to infect macrophages <it>in vitro</it>, induce lesions in BALB/c mice and infect <it>Lutzomyia longipalpis</it>.</p> <p>Conclusions</p> <p>Notwithstanding the lack of an extracellular flagellum, this isolate infects macrophages <it>in vitro </it>and produces lesions when inoculated into mice. Moreover, it is able to colonize phlebotomine sand flies. Considering the importance attributed to the flagellum in the successful infection and survival of <it>Leishmania </it>in the insect midgut and in the invasion of macrophages, these findings may bring new light into the infectious mechanisms of <it>L</it>. (<it>V</it>.) <it>braziliensis</it>.</p
Spain: Underwater Exploration on a Narrow Continental Shelf
- Author
- A Morales
- A Morales
- A Peña
- A Ruiz
- B MartĂnez DĂaz
- B MartĂnez DĂaz
- C Finlayson
- CB Stringer
- D Brandherm
- D Moura
- E Ălvarez-FernĂndez
- E Ălvarez-FernĂndez
- G Meijide
- GN Bailey
- GN Bailey
- J Altuna
- J Daura
- J Daura
- JJ BlĂĄnquez
- LG Straus
- LG Straus
- M Almagro
- M Canals
- M Cortés
- M Cortés-Sånchez
- M Jorge
- M San NicolĂĄs
- ML Ruiz-GĂĄlvez
- MR GonzĂĄlez Morales
- MS CorchĂłn
- MĂ Blas
- MĂ Fano
- MĂ SĂĄnchez Carro
- O Rivero
- P Arias
- P Arias
- R Bradley
- R Montes
- R Montes
- R Montes
- R Piqué
- X Nieto
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2020
- Field of study
In spite of Spainâs long coastline (nearly 8000 km) and its well-established tradition in underwater archaeology, the prehistoric settlement of the continental shelf is practically
unknown with very few finds. Underwater research has focused on naval archaeology and, until very recently, no attempt had been made to look for prehistoric underwater sites. In the past decade,new research projects have been launched to explore selected areas on the Cantabrian shelf and offshore of Gibraltar. This chapter summarises the currently available evidence of submerged prehistoric archaeology and the preliminary results of these new project
Mycobacterium tuberculosis Glucosyl-3-Phosphoglycerate Synthase: Structure of a Key Enzyme in Methylglucose Lipopolysaccharide Biosynthesis
- Author
- A Leslie
- AA Vaguine
- AJ McCoy
- B Heras
- B SĂĄ-Moura
- Bebiana SĂĄ-Moura
- BL Hanson
- BW Matthews
- C Breton
- CM Sassetti
- E Krissinel
- G Tuffal
- GN Murshudov
- GR Gray
- H Santos
- Haiwei Song
- IW Davis
- J Costa
- J Costa
- J Flint
- JA Ferguson
- JW Pflugrath
- K Brown
- K Kamisango
- K Mikusova
- K Persson
- K Takayama
- KK Yabusaki
- L Holm
- LL Lairson
- LS Weisman
- LS Weisman
- Luciana Albuquerque
- M Ilton
- M Wimmerova
- Milton S. da Costa
- MT Pommier
- N Empadinhas
- N Empadinhas
- Nuno Empadinhas
- P Emsley
- P Gouet
- PD Adams
- Pedro José Barbosa Pereira
- PK Qasba
- PM Coutinho
- R Laskowski
- RJ Banis
- RJ Morris
- S Berg
- Sandra Macedo-Ribeiro
- SJ Charnock
- UM Unligil
- YC Lee
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2008
- Field of study
Tuberculosis constitutes today a serious threat to human health worldwide, aggravated by the increasing number of identified multi-resistant strains of Mycobacterium tuberculosis, its causative agent, as well as by the lack of development of novel mycobactericidal compounds for the last few decades. The increased resilience of this pathogen is due, to a great extent, to its complex, polysaccharide-rich, and unusually impermeable cell wall. The synthesis of this essential structure is still poorly understood despite the fact that enzymes involved in glycosidic bond synthesis represent more than 1% of all M. tuberculosis ORFs identified to date. One of them is GpgS, a retaining glycosyltransferase (GT) with low sequence homology to any other GTs of known structure, which has been identified in two species of mycobacteria and shown to be essential for the survival of M. tuberculosis. To further understand the biochemical properties of M. tuberculosis GpgS, we determined the three-dimensional structure of the apo enzyme, as well as of its ternary complex with UDP and 3-phosphoglycerate, by X-ray crystallography, to a resolution of 2.5 and 2.7 Ă
, respectively. GpgS, the first enzyme from the newly established GT-81 family to be structurally characterized, displays a dimeric architecture with an overall fold similar to that of other GT-A-type glycosyltransferases. These three-dimensional structures provide a molecular explanation for the enzyme's preference for UDP-containing donor substrates, as well as for its glucose versus mannose discrimination, and uncover the structural determinants for acceptor substrate selectivity. Glycosyltransferases constitute a growing family of enzymes for which structural and mechanistic data urges. The three-dimensional structures of M. tuberculosis GpgS now determined provide such data for a novel enzyme family, clearly establishing the molecular determinants for substrate recognition and catalysis, while providing an experimental scaffold for the structure-based rational design of specific inhibitors, which lay the foundation for the development of novel anti-tuberculosis therapies
Breast cancer and support group in the life of mastectomized women
- Author
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Early and Late Pathogenic Events of Newborn Mice Encephalitis Experimentally Induced by Itacaiunas and CurionĂłpolis Bracorhabdoviruses Infection
- Author
- A Buki
- A Roulston
- AC German
- AC Jackson
- AP Travassos da Rosa
- AP Travassos da Rosa
- B Anlar
- B Lundh
- BJ Beaty
- BS Huneycutt
- Christina Maeda Takiya
- CL Maslin
- Cristovam Wanderley Picanço Diniz
- CS Reiss
- Daisy Elaine Andrade da Silva
- Daniele Barbosa de Almeida Medeiros
- DE Griffin
- DJ Gubler
- EA Hunsperger
- EM Barnett
- ES Reynolds
- F Lafay
- FA Murphy
- FR Lima
- G Dobler
- GJ Brewer
- GN Barber
- I Julkunen
- I Le Blanc
- IV Plakhov
- JA Diniz
- Jannifer Oliveira Chiang
- JD Rempel
- JK Fazakerley
- JK Fazakerley
- JM Forger 3rd
- José Antonio Picanço Diniz
- Juarez AntÎnio SimÔes Quaresma
- KD McCarthy
- Kendra Eyllen de Freitas Zoghbi
- LJ Martin
- M Soilu-Hanninen
- M Soilu-Hanninen
- M Vila
- Marcio Augusto GalvĂŁo Braga
- MC Dal Canto
- MM Esiri
- N Babic
- PC Charles
- Pedro Fernando da Costa Vasconcelos
- PF Vasconcelos
- Philip G. Stevenson
- PK Hepler
- S Crotty
- S Saha
- SF Elena
- ST Khuth
- ST Khuth
- SW Barthold
- T Iwasaki
- T Komatsu
- Vera Lucia Reis de Souza Barros
- Vivaldo Moura Neto
- W Gomes-Leal
- Wanderley de Souza
- WH Van der Poel
- WL Chan
- Zaire Alves dos Santos
- ZF Fu
- ZF Fu
- Ădila Liliane Barros Dias
- Publication venue
- Public Library of Science
- Publication date
- 05/03/2008
- Field of study
In previous reports we proposed a new genus for Rhabdoviridae and described neurotropic preference and gross neuropathology in newborn albino Swiss mice after Curionopolis and Itacaiunas infections. In the present report a time-course study of experimental encephalitis induced by Itacaiunas and Curionopolis virus was conducted both in vivo and in vitro to investigate cellular targets and the sequence of neuroinvasion. We also investigate, after intranasal inoculation, clinical signs, histopathology and apoptosis in correlation with viral immunolabeling at different time points. Curionopolis and Itacaiunas viral antigens were first detected in the parenchyma of olfactory pathways at 2 and 3 days post-inoculation (dpi) and the first clinical signs were observed at 4 and 8 dpi, respectively. After Curionopolis infection, the mortality rate was 100% between 5 and 6 dpi, and 35% between 8 and 15 dpi after Itacaiunas infection. We identified CNS mice cell types both in vivo and in vitro and the temporal sequence of neuroanatomical olfactory areas infected by Itacaiunas and Curionopolis virus. Distinct virulences were reflected in the neuropathological changes including TUNEL immunolabeling and cytopathic effects, more intense and precocious after intracerebral or in vitro inoculations of Curionopolis than after Itacaiunas virus. In vitro studies revealed neuronal but not astrocyte or microglial cytopathic effects at 2 dpi, with monolayer destruction occurring at 5 and 7 dpi with Curionopolis and Itacaiunas virus, respectively. Ultrastructural changes included virus budding associated with interstitial and perivascular edema, endothelial hypertrophy, a reduced and/or collapsed small vessel luminal area, thickening of the capillary basement membrane, and presence of phagocytosed apoptotic bodies. Glial cells with viral budding similar to oligodendrocytes were infected with Itacaiunas virus but not with Curionopolis virus. Thus, Curionopolis and Itacaiunas viruses share many pathological and clinical features present in other rhabdoviruses but distinct virulence and glial targets in newborn albino Swiss mice brain
HĂĄbito de assistir Ă televisĂŁo e sua relação com a alimentação: resultados do perĂodo de 2006 a 2014 em capitais brasileiras
- Author
- Bellisle F
- Blass EM
- Bowman SA
- Camelo LV
- Currie C
- Danner FW
- Dunstan DW
- Emanuella Gomes Maia
- Fernanda Mendes Dias Gomes
- Fernandes RA
- Ferreira AD
- Gardner B
- Hallal PC
- Harris JL
- Healy GN
- Henriques P
- Hu FB
- Jakes RW
- Knuth AG
- Lowry R
- Manios Y
- Marana Hauck Alves
- Marques CSM
- Marsh S
- Monteiro CA
- Monteiro CA
- Monteiro CA
- Monteiro CA
- Monteiro CA
- Moraes SA
- Morales-SuĂĄrez-Varela M
- Moreira AD
- Moura EC
- Moura EC
- Neves ACMD
- Pearson N
- Prado WL
- Rafael Moreira Claro
- Salmon J
- Story M
- Stroebele N
- Szolnokin G
- Thorp AA
- Thorp AA
- Tucker LA
- Vereeckn CA
- Wansink B
- Xie YJ
- Yara Rubia Huth
- Zhou Z
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- 01/01/2016
- Field of study
Operation and performance of the ATLAS Tile Calorimeter in Run 1
- Author
- Aaboud M
- Aad G
- Abbott B
- Abdallah J
- Abdinov O
- Abeloos B
- Abhayasinghe DK
- Abidi SH
- Abouelfadl 
- AbouZeid OS
- Abraham NL
- Abramowicz H
- Abreu H
- Abulaiti Y
- Acharya BS
- Adachi S
- Adamczyk L
- Adelman J
- Adersberger M
- Adiguzel A
- Adye T
- Affolder AA
- Afik Y
- Agheorghiesei C
- Aguilar-Saavedra JA
- Ahmadov F
- Aielli G
- Akatsuka S
- Akerstedt H
- Akilli E
- Akimov AV
- Alberghi GL
- Albert J
- Albicocco P
- Alconada Verzini MJ
- Alderweireldt S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexander G
- Alexopoulos T
- Alhroob M
- Ali B
- Alimonti G
- Alison J
- Alkire SP
- Allaire C
- Allbrooke BMM
- Allen BW
- Allport PP
- Aloisio A
- Alonso A
- Alonso F
- Alpigiani C
- Alshehri AA
- Alstaty MI
- Alvarez 
- Alviggi MG
- Amadio BT
- Amaral Coutinho Y
- Ambroz L
- Amelung C
- Amidei D
- Amor 
- Amoroso S
- Amrouche CS
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders CF
- Anders JK
- Anderson KJ
- Andreazza A
- Andrei V
- Anelli CR
- Angelidakis S
- Angelozzi I
- Angerami A
- Anisenkov AV
- Annovi A
- Antel C
- Anthony MT
- Antonelli M
- Antrim DJA
- Anulli F
- Aoki M
- Aperio Bella L
- Arabidze G
- Arai Y
- Araque JP
- Araujo Ferraz V
- Arce ATH
- Ardell RE
- Arduh FA
- Argos FC
- Arguin J-
- Argyropoulos S
- Armadans R
- Armbruster AJ
- Armitage LJ
- Armstrong A
- Arnaez O
- Arnold H
- Arratia M
- Arslan O
- Artamonov A
- Artoni G
- Artz S
- Asai S
- Asbah N
- Ashkenazi A
- Asimakopoulou EM
- Asquith L
- Assamagan K
- Astalos R
- Astigarraga ME
- Atkin RJ
- Atkinson M
- Atlay NB
- Auerbach B
- Augsten K
- Avolio G
- Avramidou R
- Axen B
- Ayoub MK
- Azuelos G
- AÌlvarez Piqueras D
- AÌkesson TPA
- Baas AE
- Baca MJ
- Bachacou H
- Bachas K
- Backes M
- Bagnaia P
- Bahilo JJL
- Bahmani M
- Bahrasemani H
- Bailey AJ
- Baines JT
- Bajic M
- Bakalis C
- Baker OK
- Bakker PJ
- Baldin EM
- Balek P
- Balli F
- Balunas WK
- Balz J
- Banas E
- Bandyopadhyay A
- Banerjee S
- Bannoura AAE
- Barak L
- Barbe WM
- Barberio EL
- Barberis D
- Barbero M
- Barillari T
- Barisits M
- Barkeloo J
- Barklow T
- Barlow N
- Barnea R
- Barnes SL
- Barnett BM
- Barnett RM
- Barnovska-Blenessy Z
- Baroncelli A
- Barone G
- Barr AJ
- Barranco Navarro L
- Barreiro GuimaraÌes da Costa J
- Barreiro F
- Bartoldus R
- Barton AE
- Bartos P
- Basalaev A
- Bassalat A
- Bates RL
- Batista SJ
- Batlamous S
- Batley JR
- Battaglia M
- Bauce M
- Bauer F
- Bauer KT
- Bawa HS
- Beacham JB
- Beattie MD
- Beau T
- Beauchemin PH
- Bechtle P
- Beck HC
- Beck HP
- Becker K
- Becker M
- Becot C
- Beddall A
- Beddall AJ
- Bednyakov VA
- Bedognetti M
- Bee CP
- Beermann TA
- Begalli M
- Begel M
- Behera A
- Behr JK
- Bell AS
- Bella G
- Bellagamba L
- Bellerive A
- Bello FA
- Bellomo M
- Belotskiy K
- Belyaev NL
- Benary O
- Benchekroun D
- Bender M
- Benekos N
- Benhammou Y
- Benhar Noccioli E
- Benitez J
- Benjamin DP
- Benoit M
- Bensinger JR
- Bentvelsen S
- Beresford L
- Beretta M
- Berge D
- Bergeaas Kuutmann E
- Berger N
- Bergsten LJ
- Beringer J
- Berlendis S
- Bernard NR
- Bernardi G
- Bernius C
- Bernlochner FU
- Berry T
- Berta P
- Bertella C
- Bertoli G
- Bertram IA
- Besjes GJ
- Bessidskaia Bylund O
- Bessner M
- Besson N
- Bethani A
- Bethke S
- Betti A
- Bevan AJ
- Beyer J
- Bianchi RM
- Biebel O
- Biedermann D
- Bielski R
- Bierwagen K
- Biesuz NV
- Biglietti M
- Billoud TRV
- Bindi M
- Bingul A
- Bini C
- Biondi S
- Bisanz T
- Biswal JP
- Bittrich C
- Bjergaard DM
- Black JE
- Black KM
- Blair RE
- Blazek T
- Bloch I
- Blocker C
- Blue A
- Blumenschein U
- Blunier D
- Bobbink GJ
- Bobrovnikov VS
- Bocchetta SS
- Bocci A
- Boerner D
- Bogavac D
- Bogdanchikov AG
- Bohm C
- Boisvert V
- Bokan P
- Bold T
- Boldyrev AS
- Bolz AE
- Bomben M
- Bona M
- Bonilla JS
- Boonekamp M
- Borisov A
- Borissov G
- Bortfeldt J
- Bortoletto D
- Bortolotto V
- Boscherini D
- Bosman M
- Bossio Sola JD
- Bostanabad M
- Bouaouda K
- Boudreau J
- Bouhova-Thacker EV
- Boumediene D
- Bourdarios C
- Boutle SK
- Boveia A
- Boyd J
- Boyko IR
- Bozson AJ
- Bracinik J
- Brahimi N
- Brandt A
- Brandt G
- Brandt O
- Braren F
- Bratzler U
- Brau B
- Brau JE
- Breaden Madden WD
- Brendlinger K
- Brennan AJ
- Brenner L
- Brenner R
- Bressler S
- Brickwedde B
- Briglin DL
- Britton D
- Britzger D
- Brock I
- Brock R
- Brooijmans G
- Brooks T
- Brooks WK
- Brost E
- Broughton JH
- Brown H
- Bruckman de Renstrom PA
- Bruncko D
- Bruni A
- Bruni G
- Bruni LS
- Bruno S
- Brunt BH
- Bruschi M
- Bruscino N
- Bryant P
- Bryngemark L
- Buanes T
- Buat Q
- Buchholz P
- Buckley AG
- Budagov IA
- Bugge MK
- Bulekov O
- Bullock D
- Burch TJ
- Burdin S
- Burgard CD
- Burger AM
- Burghgrave B
- Burka K
- Burke S
- Burmeister I
- Burr JTP
- Busato E
- Buschmann E
- Bussey P
- Butler JM
- Buttar CM
- Butterworth JM
- Butti P
- Buttinger W
- Buzatu A
- Buzykaev AR
- BuÌhrer F
- BuÌscher D
- BuÌscher V
- Cabras G
- Cabrera UrbaÌn S
- Caforio D
- Cai H
- Cairo VMM
- Cakir I
- Cakir O
- Calace N
- Calafiura P
- Calandri A
- Calderini G
- Calfayan P
- Callea G
- Caloba LP
- Calvente Lopez S
- Calvet D
- Calvet S
- Calvet TP
- Calvetti M
- Camacho Toro R
- Camarda S
- Camarri P
- Cameron D
- Caminal 
- Camincher C
- Campana S
- Campanelli M
- Camplani A
- Campoverde A
- Canale V
- Cano Bret M
- Cantero J
- Cao T
- Cao Y
- Capeans Garrido MDM
- Caprini I
- Caprini M
- Capua M
- Carbone RM
- Cardarelli R
- Cardillo FC
- Carli I
- Carli T
- Carlino G
- Carlson BT
- Carminati L
- Carney RMD
- Caron S
- Carquin E
- CarraÌ S
- Carrillo-Montoya GD
- Casadei D
- Casado MP
- Casha AF
- Casolino M
- Casper DW
- Castelijn R
- Castillo Gimenez V
- Castillo FL
- Castro NF
- Catinaccio A
- Catmore JR
- Cattai A
- Caudron J
- Cavaliere V
- Cavallaro E
- Cavalli D
- Cavalli-Sforza M
- Cavasinni V
- Celebi E
- Ceradini F
- Cerda Alberich L
- Cerqueira AS
- Cerri A
- Cerrito L
- Cerutti F
- Cervelli A
- Cetin SA
- Chafaq A
- Chakraborty D
- Chan SK
- Chan WS
- Chan YL
- Chang P
- Chapman JD
- Charlton DG
- Chau CC
- Chavez Barajas CA
- Che S
- Chegwidden A
- Chekanov S
- Chekulaev SV
- Chelkov GA
- Chelstowska MA
- Chen C
- Chen CH
- Chen H
- Chen J
- Chen J
- Chen S
- Chen SJ
- Chen X
- Chen Y
- Chen Y
- Cheng HC
- Cheng HJ
- Cheplakov A
- Cheremushkina E
- Cherkaoui El Moursli R
- Cheu E
- Cheung K
- Chevalier L
- Chiarella V
- Chiarelli G
- Chiodini G
- Chisholm AS
- Chitan A
- Chiu I
- Chiu YH
- Chizhov MV
- Choi K
- Chomont AR
- Chouridou S
- Chow YS
- Christodoulou V
- Chu MC
- Chudoba J
- Chuinard AJ
- Chwastowski JJ
- Chytka L
- Ciaccio A
- Ciaccio L
- Cinca D
- Cindro V
- CioaraÌ IA
- Ciocio A
- Cirotto F
- Citron ZH
- Citterio M
- Clark A
- Clark MR
- Clark PJ
- Clement C
- Clemente WK
- Coadou Y
- Cobal M
- Coccaro A
- Cochran J
- Coimbra AEC
- Colasurdo L
- Cole B
- Colijn AP
- Collot J
- Conde MuinÌo P
- Coniavitis E
- Connell SH
- Connelly IA
- Constantinescu S
- Conventi F
- Cooper-Sarkar AM
- Cormier F
- Cormier KJR
- Corradi M
- Correia AM
- Corrigan EE
- Corriveau F
- Cortes-Gonzalez A
- Costa MJ
- Costanzo D
- Cottin G
- Cowan G
- Cox BE
- Crane J
- Cranmer K
- Crawley SJ
- Creager RA
- Cree G
- Crescioli F
- CreÌpeÌ-Renaudin S
- Cristinziani M
- Croft V
- Crosetti G
- Cueto A
- Cuhadar Donszelmann T
- Cukierman AR
- Cunha 
- Curatolo M
- CuÌth J
- Czekierda S
- Czodrowski P
- Da Via C
- Da 
- Dabrowski W
- Dado T
- Dahbi S
- Dai T
- Dallaire F
- Dallapiccola C
- Dam M
- Damp J
- Dandoy JR
- Daneri MF
- Dang NP
- Dann ND
- Danninger M
- Dao V
- Darbo G
- Darmora S
- Dartsi O
- Dattagupta A
- Daubney T
- Davey W
- David C
- Davidek T
- Davis DR
- Davydov Y
- Dawe E
- Dawson I
- De Asmundis R
- De Benedetti A
- De Castro S
- De Cecco S
- De Groot N
- de Jong P
- De la Torre H
- De Lorenzi F
- De Maria A
- De Moura 
- De Pedis D
- De Salvo A
- De Sanctis U
- De Santo A
- De Vasconcelos Corga K
- De Vivie 
- De 
- De 
- De K
- Debenedetti C
- Dedovich DV
- Dehghanian N
- Del Gaudio M
- Del Peso J
- Delgado A
- Delgove D
- Deliot F
- Delitzsch CM
- Della Pietra M
- Della Volpe D
- DellâAcqua A
- DellâAsta L
- Delmastro M
- Delporte C
- Delsart PA
- DeMarco DA
- Demers S
- Demichev M
- Denisov SP
- Denysiuk D
- Derendarz D
- Derkaoui JE
- Derue F
- Dervan P
- Desch K
- Deterre C
- Dette K
- Devesa MR
- Deviveiros PO
- Dewhurst A
- Dhaliwal S
- Di 
- Di 
- Di 
- Di 
- Di 
- Di 
- Di 
- Di 
- Di 
- Di 
- Di 
- Di 
- Diaconu C
- Diamond M
- Dias 
- Dias FA
- Diaz LP
- Diaz MA
- Dickinson J
- Diehl EB
- Dietrich J
- Dimitrievska A
- Dingfelder J
- Dittus F
- DiÌez Cornell S
- Djama F
- Djobava T
- Djuvsland JI
- Do 
- Do 
- Dobre M
- Dodsworth D
- Doglioni C
- Dolejsi J
- Dolezal Z
- Donadelli M
- Donato C
- Donini J
- Dopke J
- Doria A
- Dortz O
- Dos 
- Dova MT
- Doyle AT
- Drechsler E
- Dreyer E
- Dreyer T
- Dris M
- Du Y
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- Zwalinski L
- ZÌenisÌ T
- ZÌivkovicÌ L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
The Tile Calorimeter is the hadron calorimeter covering the central region of the ATLAS experiment at the Large Hadron Collider. Approximately 10,000 photomultipliers collect light from scintillating tiles acting as the active material sandwiched between slabs of steel absorber. This paper gives an overview of the calorimeterâs performance during the years 2008â2012 using cosmic-ray muon events and protonâproton collision data at centre-of-mass energies of 7 and 8TeV with a total integrated luminosity of nearly 30 fbâ1. The signal reconstruction methods, calibration systems as well as the detector operation status are presented. The energy and time calibration methods performed excellently, resulting in good stability of the calorimeter response under varying conditions during the LHC Run 1. Finally, the Tile Calorimeter response to isolated muons and hadrons as well as to jets from protonâproton collisions is presented. The results demonstrate excellent performance in accord with specifications mentioned in the Technical Design Report
Measurement and interpretation of same-sign W boson pair production in association with two jets in pp collisions at s = 13 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abeling K
- Abicht NJ
- Abidi SH
- Aboulhorma A
- Abramowicz H
- Abreu H
- Abulaiti Y
- Abusleme Hoffman AC
- Acharya BS
- Adam Bourdarios C
- Adamczyk L
- Adamek L
- Addepalli SV
- Addison MJ
- Adelman J
- Adiguzel A
- Adye T
- Affolder AA
- Afik Y
- Agaras MN
- Agarwala J
- Aggarwal A
- Agheorghiesei C
- Ahmad A
- Ahmadov F
- Ahmed WS
- Ahuja S
- Ai X
- Aielli G
- Aikot A
- Ait Tamlihat M
- Aitbenchikh B
- Aizenberg I
- Akbiyik M
- Akimov AV
- Akiyama D
- Akolkar NN
- Al Khoury K
- Alberghi GL
- Albert J
- Albicocco P
- Albouy GL
- Alderweireldt S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexopoulos T
- Alfonsi F
- Algren M
- Alhroob M
- Ali B
- Ali HMJ
- Ali S
- Alibocus SW
- Aliev M
- Alimonti G
- Alkakhi W
- Allaire C
- Allbrooke BMM
- Allen JF
- Allendes Flores CA
- Allport PP
- Aloisio A
- Alonso F
- Alpigiani C
- Alvarez Estevez M
- Alvarez Fernandez A
- Alves Cardoso M
- Alviggi MG
- Aly M
- Amaral Coutinho Y
- Ambler A
- Amelung C
- Amerl M
- Ames CG
- Amidei D
- Amor Dos Santos SP
- Amos KR
- Ananiev V
- Anastopoulos C
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- Anders JK
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- Zhemchugov A
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- Ă kesson TPA
- Ăncel ĂO
- ĆœeniĆĄ T
- ĆœivkoviÄ L
- Publication venue
- Springer Nature
- Publication date
- 01/04/2024
- Field of study
This paper presents the measurement of fducial and diferential cross sections for both the inclusive and electroweak production of a same-sign W-boson pair in association with two jets (W±W±jj) using 139 fbâ1 of proton-proton collision data recorded at a centre-of-mass energy of âs = 13 TeV by the ATLAS detector at the Large Hadron Collider. The analysis is performed by selecting two same-charge leptons, electron or muon, and at least two jets with large invariant mass and a large rapidity diference. The measured fducial cross sections for electroweak and inclusive W±W±jj production are 2.92 ± 0.22 (stat.) ± 0.19 (syst.)fb and 3.38±0.22 (stat.)±0.19 (syst.)fb, respectively, in agreement with Standard Model predictions. The measurements are used to constrain anomalous quartic gauge couplings by extracting 95% confdence level intervals on dimension-8 operators. A search for doubly charged Higgs bosons H±± that are produced in vector-boson fusion processes and decay into a same-sign W boson pair is performed. The largest deviation from the Standard Model occurs for an H±± mass near 450 GeV, with a global signifcance of 2.5 standard deviations
Combination of searches for heavy spin-1 resonances using 139 fbâ1 of proton-proton collision data at s = 13 TeV with the ATLAS detector
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- Zhang Y
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- Zhang Z
- Zhao H
- Zhao T
- Zhao Y
- Zhao Z
- Zhao Z
- Zhemchugov A
- Zheng J
- Zheng K
- Zheng X
- Zheng Z
- Zhong D
- Zhou B
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- Zhu CG
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- Zhu Y
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- Zhukov K
- Zimine NI
- Zinsser J
- Ziolkowski M
- Zoccoli A
- Zoch K
- Zorbas TG
- Zormpa O
- Zou W
- Zwalinski L
- Ă kesson TPA
- Ăncel ĂO
- ĆœeniĆĄ T
- ĆœivkoviÄ L
- Publication venue
- Springer Nature
- Publication date
- 19/04/2024
- Field of study
A combination of searches for new heavy spin-1 resonances decaying into different pairings of W, Z, or Higgs bosons, as well as directly into leptons or quarks, is presented. The data sample used corresponds to 139 fbâ1 of proton-proton collisions at
= 13 TeV collected during 2015â2018 with the ATLAS detector at the CERN Large Hadron Collider. Analyses selecting quark pairs (qq, bb,
, and tb) or third-generation leptons (ÏÎœ and ÏÏ) are included in this kind of combination for the first time. A simplified model predicting a spin-1 heavy vector-boson triplet is used. Cross-section limits are set at the 95% confidence level and are compared with predictions for the benchmark model. These limits are also expressed in terms of constraints on couplings of the heavy vector-boson triplet to quarks, leptons, and the Higgs boson. The complementarity of the various analyses increases the sensitivity to new physics, and the resulting constraints are stronger than those from any individual analysis considered. The data exclude a heavy vector-boson triplet with mass below 5.8 TeV in a weakly coupled scenario, below 4.4 TeV in a strongly coupled scenario, and up to 1.5 TeV in the case of production via vector-boson fusion
Contributions to the history of ocular toxoplasmosis in Southern Brazil
- Author
- Alves LS
- Chaplin EL
- Degrazia CO
- Dubey JP
- Eckert GU
- Estacia P
- Esteves JF
- Gilbert RE
- Giraldi N
- Glasner PD
- Holland GN
- Holland GN
- Hyakutake S
- J Melamed
- Jones L
- Khan A
- Lago EG
- Lago EG
- Lavinsky J
- Martins LD
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Melamed J
- Moura L
- Mozzatto L
- Neto EC
- Neto RB
- Neves JM
- Nishikawa H
- Nussenblatt RB
- OsĂłrio LA
- Perkins ES
- Raymundi AA
- Reis MM
- Reis MM
- Santos EM
- Sebben JC
- Silva NN
- Silveira C
- Silveira C
- Silveira C
- Silveira C
- Silveira C
- Silveira CM
- Spalding SM
- Spalding SM
- Tavares ALC
- Vallochi AL
- Vallochi AL
- Varella IS
- Yamamoto JH
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
- âŠ