10 research outputs found
A responsabilidade social ambiental e a problemática dos aviários do Concelho de Sátão
- Publication venue
- Universidade de Aveiro
- Publication date
- 01/01/2009
- Field of study
Mestrado em Contabilidade - AuditoriaA presente dissertação pretende apresentar uma nova realidade no ambiente empresarial, onde se evidencia um movimento pela ética empresarial e pela responsabilidade social. A poluição, a corrupção, o desemprego e a proteção dos consumidores foram alguns dos temas apontados por esta dissertação para que o debate sobre a responsabilidade social se acentuasse. Sendo assim, esta dissertação procura estudar os problemas ambientais e as soluções para os mesmos, bem como a forma das empresas contribuirem para a satisfação das necessidades dos seus clientes, gerindo simultaneamente as expectativas dos seus trabalhadores, fornecedores e comunidade local. Desta forma contribui-se de uma forma positiva para a sociedade, o que poderá proporcionar vantagens directas para o negócio e assegurar a competitividade a longo prazo. Nesta sequência, foi realizado um estudo sobre a responsabilidade sócio-ambiental nos aviários de produção de aves do Concelho de Sátão onde se verificou que parte dos recursos destes aviários é investido em acções sociais e ambientais, facto que legitima o seu papel perante a sociedade como defensora do bem-estar ambiental.This dissertation aims to present a new reality in the business environment, which shows a movement in favor of the business ethics and social responsibility. Pollution, corruption, unemployment and consumer protection are some of the issues raised by this dissertation to the debate on social responsibility. Therefore, this dissertation seeks to study the environmental problems and solutions to them, and how businesses contribute to meeting the needs of its customers, while managing the expectations of their employees, suppliers and local community. This contributes in a positive way to society, which can provide direct benefits to the business and ensure the long-term competitiveness. Following this, a study was conducted on the socio-environmental responsibility in production of poultry birds in Sátão where was verified that part of the resources are invested in social and environmental actions, which legitimizes its role in society as defender of the welfare environment
Por uma epistemologia emancipatória da promoção da saúde
- Author
- AVRITZER Leonardo
- CARVALHO Maria Alice P.
- CARVALHO Maria Alice P.
- CZERESNIA Dina
- DAHRENDORF Ralf
- DIEGUES Antônio C.S.
- FREIRE Paulo
- FREIRE Paulo
- FREIRE Paulo
- FREIRE Paulo
- FREITAS Ana Lúcia S.
- MARCIAL Elaine C.
- MARQUES Luciana R.
- MINAYO Maria Cecília S.
- NUNES João Arriscado
- O'CONNOR James
- PEREIRA Marcus A.
- PIVETTA Fátima
- REIS Márcio C.
- RIGOTTO Raquel M.
- ROZEMBERG Brani
- SANTOS Boaventura de Sousa
- SANTOS Boaventura de Sousa
- SANTOS Boaventura de Sousa
- SANTOS Boaventura de Sousa
- SANTOS Boaventura de Sousa
- SANTOS Boaventura de Sousa
- SANTOS Milton
- SCHÜTZ Gabriel Eduardo
- SILVA Luiz Antonio M.
- VALLA Vitor V.
- VIANA Ana Luiza D'Ávila
- WAGNER Peter
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Characterisation of microbial attack on archaeological bone
- Author
- Abrantes Ana M
- Abreu Ana C
- Abreu Renato
- Abreu Renato
- Abreu Wilson
- Acedo Guadalupe
- Afonso Carlos
- Afreixo Vera
- Agudelo Mª E
- Alarcão Violeta
- Albuquerque Carlos
- Albuquerque Carlos
- Albuquerque Carlos
- Alencar Liana
- Alferes Valentim R
- Aliseda Isabel R
- Almada Lívia F
- Almeia António
- Almeida Ana
- Almeida Ana
- Almeida António
- Almeida António
- Almeida Armando
- Almeida Armando
- Almeida Fabrícia M
- Almeida Henrique
- Almeida Henrique A
- Almeida Henrique A
- Almeida Inês
- Almeida Jorge
- Almeida José P
- Almeida Maria
- Almeida Pedro
- Almeida Sidalina
- Alvarenga-Martins Nathália
- Alves B.
- Alves B.
- Alves Celeste
- Alves Dina
- Alves Gilberto
- Alves Helder
- Alves Josiane
- Alves José M
- Alves Juliana
- Alves Júlia M
- Alves Nuno
- Alves Nuno
- Alves Samuel
- Amado Diogo
- Amado João
- Amado Sandra
- Amaral Ana P
- Amaral Ana P
- Amaral Odete
- Amaral Odete
- Amaral Odete
- Amaral Odete
- Amaral Odete
- Ambrósio Sara
- Amendoeira José
- Amorim Ana
- Amorim Ana P
- Amorim Helena
- Andrade Diogo
- Andrade Isabel
- Andrade Isabel
- Andrade Isabel
- Andrade Isabel
- Andrade Isabel
- Andrade Isabel
- Andrade J. A
- Andrade Karizia V
- Andrade Renato
- Andrade Renato
- Andrade Susana
- Antunes Ana
- Antunes Ana
- Antunes Cristina
- Antunes Lígia
- Antunes Sandra
- Antunes Sandra
- Aparício Graça
- Aparício Graça
- Aparício José
- Apolinário-Hagen Jennifer
- Apolinário-Hagen Jennifer
- Aquino Caroline Q
- Aquino Caroline Q
- Aquino Priscila S
- Aquino Priscila S
- Araujo André R
- Araújo Beatriz
- Araújo Elsa
- Araújo Lia
- Araújo Odete
- Araújo Odete
- Araújo Patrícia
- Araújo Patrícia
- Araújo Patrícia
- Armas-Gonzalez Yadira
- Arreguy-Sena Cristina
- Arreguy-Sena Cristina
- Ascenso Rita T
- Ascenso Rita T
- Assunção Victor
- Augusto Cláudia
- Avelelas Francisco
- Ayoub Rodrigo
- Azeredo Zaida
- Azeredo Zaida
- Azeredo Zaida
- Azeredo Zaida
- Azevedo Julieta
- Azevedo Julieta
- Azevedo Marcelo
- Azevedo Maria H
- Azevedo Mª H
- Azevedo Tatiana
- Azzalis L.
- Baffour Gabriel
- Baffour Gabriel
- Bairros Keila
- Baixinho Cristina L
- Bajo Roberto
- Baltazar Ana L
- Barbeiro Ana P
- Barbosa Flávio
- Barbosa Tiago
- Barreira Eduarda
- Barreiros Luísa
- Barros Luísa
- Barros Luísa
- Barros Teresa
- Barroso Isabel
- Barroso Isabel
- Barroso Isabel
- Barroso João
- Basto Marta L
- Basto Marta L
- Basto Marta L
- Bastos Fernanda
- Bastos Fernanda
- Batalha Joana
- Batista Marco
- Batista Marco
- Batista Marco
- Batista Rita
- Baylina Pilar
- Becerra Isabel A
- Bellém Fernando
- Bellém Fernando
- Belo Pedro
- Benevides Joana
- Benevides Joana
- Bento Elisabete
- Bento Elisabete
- Bento Sandrina
- Bento Teresa
- Bergland Astrid
- Bernardes Lúcia G
- Bernardes Tiago
- Bernardo Helena
- Bexiga Filipa
- Bianchini Bruna
- Bizarro Carla
- Björklund Anita
- Blanco Valeriana G
- Boavida José
- Bonfim Luís
- Bordin Ronaldo
- Bordin Ronaldo
- Bordini Magali
- Borges Raphaelle
- Botelho Mª F
- Braga Fátima
- Braga Luciene
- Braga Luciene M
- Braga Luciene M
- Braga Margarida
- Branco Marco
- Brandão Daniela
- Brandão Daniela
- Brandão Frederico
- Brandão Piedade
- Brandão Teresa
- Bravo Rafael
- Bravo Rafael
- Breda São J
- Brito Alice
- Brito António
- Brito Irma
- Brito Luísa S
- Brito Nuno
- Brooks Dina
- Brunhoso Germana
- Brás Carina
- Brás Manuel
- Brêda Mª S J
- Bye Asta
- Caballero Francisco P
- Caballero Francisco P
- Caballero Francisco P
- Cabral Cremilde
- Cabral Gil
- Cabral Isabel
- Cabral Joana
- Cabral Lídia
- Cabral Priscila P
- Cabrita José
- Caceiro Elisa F
- Cadorio Inês
- Caeiro Patrícia
- Caldeira Suzana N
- Calha António
- Calha António
- Calvo Cristina
- Calvo Mª C
- Camarinha Luís
- Camarinha Luís
- Camarneiro Ana
- Camarneiro Ana
- Caminha Madson
- Campi Liliana
- Campofiorito C.
- Campos Maria
- Campos Maria
- Campos Mariana
- Campos Mª J
- Capelas Sylvie
- Cardoso Américo
- Cardoso Andreia
- Cardoso Ilda
- Cardoso Margarida
- Cardoso Mário E
- Cardoso Sara
- Cardoso Susana
- Carecho Nélio
- Carmen Barriga
- Carmo A.
- Carmo Bruno M
- Carneiro Juliana
- Carneiro Lara
- Carneiro Lara
- Carneiro M. A
- CaroMinghelli Eulália
- Carreira Diana
- Carreiras Diogo
- Carrão Luís
- Carvalhais Maribel
- Carvalhais Maribel
- Carvalho Amâncio
- Carvalho António
- Carvalho Carla
- Carvalho Carla
- Carvalho Carla
- Carvalho Carla
- Carvalho Carla
- Carvalho Carla
- Carvalho Célia B
- Carvalho Célia B
- Carvalho Célia B
- Carvalho Daniel
- Carvalho Daniel
- Carvalho Daniel
- Carvalho Daniel
- Carvalho Daniel
- Carvalho Francisco L
- Carvalho Inês
- Carvalho Joana
- Carvalho Lisiane L
- Carvalho Lisiane L
- Carvalho Lucinda
- Carvalho Nelma
- Carvalho Rosa
- Carvalho Rui
- Carvalho Sara
- Carvalho Sérgio
- Carvalho Teresa
- Carvalho Teresa
- Carvalho Tiago
- Carvalho Yara M
- Casalta-Lopes João
- Casas-Novas Mónica
- Caseiro Armando
- Caseiro Armando
- Caseiro Armando
- Caseiro Armando
- Caseiro Armando
- Casimiro Ana P
- Castilho Amélia
- Castilho Amélia
- Castilho Amélia
- Castilho Amélia
- Castilho Paula
- Castro Conceição
- Castro Régia B
- Castuera Ruth J
- Catarino Elisabete
- Catarino Helena
- Catarino Helena
- Catarino Helena
- Catarino Helena
- Catela David
- Cavalheiro Luís
- Cavalheiro Luís
- Certo Ana
- Cervato-Mancuso Ana M
- Cezanne Catarina
- Charepe Zaida
- Charepe Zaida
- Cheio Mónica
- Chen Gang
- Chung Wu F
- Clara João G
- Coelho Alexandre
- Coelho André
- Coelho Carina
- Coelho Elza S
- Coelho Inês
- Coelho Inês
- Coelho Luís
- Coelho Luís
- Coelho P.
- Coelho Patrícia
- Coelho Patrícia
- Colaço Armanda
- Colaço Armanda
- Colaço Diogo
- Collado-Mateo Daniel
- Collado-Mateo Daniel
- Combadão Jaime
- Conceição Milena A
- Conde Jorge
- Cordeiro Eugénio
- Cordeiro Marina
- Cordeiro Marina
- Cordeiro Marina
- Cordeiro Marina
- Cordeiro Marina
- Cordeiro Marina
- Cordeiro Raul
- Correia André
- Correia Jony
- Correia Telma
- Costa Ana R
- Costa André
- Costa Cláudia
- Costa Diana
- Costa Diana
- Costa Emília
- Costa Joyce O
- Costa Joyce O
- Costa Pablo O
- Costa Ricardo
- Costa Rui
- Costa Tânia
- Costa Tânia
- Costa Vanessa
- Coucelo Tiago
- Coutinho André P
- Coutinho Paula
- Couto Cristina
- Couto Diana
- Couto Margarida
- Couto Margarida
- Cova Marco P
- Cruz Agostinho
- Cruz Agostinho
- Cruz Agostinho
- Cruz Agostinho
- Cruz Agostinho
- Cruz Agostinho
- Cruz Bárbara
- Cruz Graça
- Cruz Inês
- Cruz Inês
- Cruz Joana
- Cruz Joana
- Cruz João
- Cruz Pedro
- Cruz Rui
- Cruz Rui
- Cruz Rui
- Cruz Susana
- Cruz x
- Cunha Fátima
- Cunha Madalena
- Cunha Madalena
- Cunha Madalena
- Cunha Madalena
- Cunha Madalena
- Cunha Marina
- Cunha Marina
- Cunha Marina
- Cunha Marina
- Cunha Marina
- Cunha Marina
- Cunha Marina
- Cunha Marina
- Cunha Marina
- Cândido Anabela
- César Ana F
- Da Motta Carolina
- Da Motta Carolina
- Da Motta Carolina
- Daniel Fernanda
- Dantas Estélio
- Deodato Sérgio
- Desouzart Gustavo
- Dias Alberto P
- Dias António
- Dias Hélia
- Dias Sara S
- Dias Sara S
- Dias Sara S
- Dias Tiago
- Dinis Alexandra
- Dinis Alexandra
- Dixe Anjos
- Dixe Anjos
- Dixe Anjos
- Dixe Maria
- Dixe Maria D A
- Dixe Maria D A
- Dixe Mª A
- Dixe Mª A
- Dixe Mª A
- Dixe Mª A
- Dixe Mª A
- Dixe Mª A
- Domingos Joana
- Domingos Samuel
- Domingues Cátia
- Domingues Gabriela
- Domingues J. N
- Dreyer Laysa C
- Duarte Catarina
- Duarte Diana
- Duarte Diana
- Duarte Hugo
- Duarte Hugo
- Duarte João
- Duarte João
- Duarte João
- Duarte Mafalda
- Duarte Nuno
- Duarte Soraia
- Duarte Soraia
- Escanciano Susana R
- Escoval Ana
- Espada Mário
- Esteves Mª R
- Estevez Gustavo L
- Estrela Jéssica
- Evangelista Diana
- Faria Luís
- Faria Luís
- Faria Melissa
- Faria Paula
- Faria Paula
- Faustino António
- Faustino António
- Faustino António
- Fernandes Adília
- Fernandes Ana R
- Fernandes Andreia
- Fernandes Beatriz
- Fernandes Helder M
- Fernandes Jorge C
- Fernandes Morgana C
- Fernandes Patrícia
- Fernandes Patrícia
- Fernandes Paula
- Fernandes Paula O
- Fernandes Paula O
- Fernandes Renato
- Fernandes Rosina
- Fernandes Rosina
- Fernandes Rosina
- Fernandes Telma
- Fernandez Mª J L
- Ferraz Maira
- Ferraz Vera
- Ferreira Ana
- Ferreira Ana
- Ferreira Ana
- Ferreira Ana
- Ferreira António
- Ferreira António
- Ferreira Carlos
- Ferreira Cláudia
- Ferreira Cláudia
- Ferreira Cláudia
- Ferreira Cláudia
- Ferreira Dora
- Ferreira Eduardo
- Ferreira Eduardo
- Ferreira Irina
- Ferreira José
- Ferreira José
- Ferreira José P
- Ferreira Lino
- Ferreira Manuela
- Ferreira Manuela
- Ferreira Manuela
- Ferreira Manuela
- Ferreira Margarida
- Ferreira Margarida
- Ferreira Margarida
- Ferreira Margarida
- Ferreira Nelson
- Ferreira P.
- Ferreira Paulo P
- Ferreira Paulo P
- Ferreira Paulo P
- Ferreira Paulo P
- Ferreira Pedro
- Ferreira Pedro
- Ferreira Pedro
- Ferreira Pedro
- Ferreira Pedro
- Ferreira Pedro
- Ferreira Pedro L
- Ferreira Regina
- Ferrito Cândida
- Ferro-Lebres Vera
- Festas Clarinda
- Figueiredo Amélia
- Figueiredo Ana G
- Figueiredo Daniela
- Figueiredo J.
- Figueiredo João
- Figueiredo João P
- Figueiredo João P
- Figueiredo João P
- Figueiredo Mª C
- Figueiredo Mª H
- Figueiredo Mª H
- Figueiredo Paulo
- Filho Braulio L
- Filho João G
- Filho João G
- Filho João G
- Filipe Vítor
- Fiorin Bruno H
- Fleig Tânia C
- Fleig Tânia C
- Fonseca Ana R
- Fonseca F.
- Fonseca F.
- Fonseca Virgínia
- Fonseca Virgínia
- Fonseca-Pinto Rui
- Fonseca-Pinto Rui
- Fonseca-Pinto Rui
- Fonseca-Pinto Rui
- Fontana Karine C
- Fontes-Ribeiro Carlos
- Forte Henriqueta D
- Fotschl Ulrike
- Frade João G
- Frade João G
- Frade João G
- Francisco Irene
- Franco Débora
- Franco-Borges Graciete
- Freire Ana
- Freitas Alberto
- Freitas Gregório
- Freitas Gregório
- Freitas João
- Freitas Kátia
- Freitas Maria
- Freitas Otília
- Freitas Otília
- Freitas Vívien A
- Frigo Leticia
- Froemming Miriam B
- Fuentes-Broto Lorena
- Furtado Alessandra S
- Furtado G.
- Furtado Guilherme
- Furtado Guilherme
- Furtado Guilherme E
- G.Silva Anne
- Gabriel António
- Gabriel António
- Gabriel António
- Gabriel António
- Gabriel António
- Gabriel Joaquim
- Gabriel Joaquim
- Galhardo Ana
- Galhardo Ana
- Galhardo Ana
- Galhardo Ana
- Galvão Ana
- Galvão Ana
- Galvão Ana
- Galvão Sofia
- Gama Ester
- Gama João
- Ganho-Ávila Ana
- Garcia Ana P
- Garcia Inês
- Garcia Teresa
- Garcia-Gordillo Miguel A
- Garcia-Gordillo Miguel A
- Garrido António
- Gaspar Filomena
- Gaspar Filomena
- Gaudêncio Iris
- Gehrke F.
- Gehrke F.
- Gisin Stefan
- Glória Margarida
- Gomes Ana A
- Gomes Ana A
- Gomes Antônio T
- Gomes Catarina
- Gomes Fernando
- Gomes José
- Gomes José C
- Gomes José H
- Gomes José H
- Gomes José H
- Gomes João
- Gomes João
- Gomes João
- Gomes João
- Gomes João
- Gomes Lisa
- Gomes Maria
- Gomes Mª J
- Gomes Pedro
- Gomes Sofia
- Gomez Inmaculada R
- Gonzalez Estefania P
- González Jesús A
- Gonçalves Amadeu
- Gonçalves Ana
- Gonçalves Ana
- Gonçalves Ana C
- Gonçalves Guilherme
- Gonçalves Liliana
- Gonçalves Narcisa
- Gonçalves Rita
- Gonçalves Rodrigo
- Gonçalves Rui
- Gonçalves Rui
- Gonçalves Óscar
- Gordo Clementina
- Gordo Sara
- Goulart Cássia L
- Goulão Beatriz
- Grande Carla
- Granjo Paulo
- Graveto João
- Graveto João
- Graveto João
- Graveto João
- Graça Anabela
- Graça Pedro
- Guedelha Daniel
- Guedes Jenifer
- Guedes Jenifer
- Guedes Joana
- Guerra Magda
- Guerreiro Sabrina L
- Guerrero Jose T
- Guerrero Jose T
- Guerrero José T
- Guerrero José T
- Guimarães Pedro
- Guimarães Teresa
- Guimarães Teresa
- Gusi Narcis
- Gutierrez Milagros L
- Hall Andreia
- Heitor Mª J
- Henriques Carolina
- Henriques Carolina G
- Henriques Mª A
- Hernandez-Martinez Francisco J
- Hernandez-Martinez Francisco J
- Hernández-Martínez Francisco-José
- Hesse Camilla
- Honório Samuel
- Honório Samuel
- Honório Samuel
- Honório Samuel
- Honório Samuel
- Horta Lina G
- Huertas Mª J T
- Iezzi Angelo
- Jardim Ana
- Jardim Helena G
- Jardim Jacinto
- Jesus C.
- Jesus C.
- Jesus Carlos
- Jesus Luís
- Jesus Rita
- Jesus Ângelo
- Jesus Ângelo
- Jesus Ângelo
- Jesus Ângelo
- Jimenez Nuria R
- Jimenez-Castuera Ruth
- Jimenez-Diaz Juan F
- Jimenez-Diaz Juan F
- Jimenez-Rodriguez Carla
- Jiménez-Díaz Juan-Fernando
- Jiménez-Díaz Juan-Fernando
- Jiménez-Rodríguez Carla
- Jordão Célia
- Jorge Arminda
- José Helena
- João Paulo V
- João Paulo V
- Jácome Cristina
- Jácome Cristina
- Kaliniczenco A.
- Kniess Rosiane
- Kranz Luís F
- Kranz Luís F
- Kraus Teresa
- Kraus Teresa
- Kretzer Marcia
- Kretzer Marcia
- Kretzer Marcia
- Kretzer Marcia
- Kretzer Marcia
- Kretzer Marcia
- Kretzer Marcia R
- Kretzer Márcia R
- Kurcgant Paulina
- Lacerda Josimari T
- Lacerda Josimari T
- Lacerda Josimari T
- Lage Isabel
- Lagoa Matilde
- Lains Jorge
- Lapa Leila
- Laranjeira Carlos
- Laranjo Mafalda
- Leal Jéssica
- Lebre Paula
- Lebre Sara
- Lee Huei D
- Leitão Catarina
- Leitão Céu
- Leitão Céu
- Leitão José A
- Lessa Paula A
- Leça Andrea
- Lima Adman S
- Lima Cristóvão F
- Lima Teresa M
- Lima Vera
- Lima-Basto Marta
- Lindo João
- Lindo João
- Lirk Gerald
- Lobato João
- Lobão Catarina
- Lopes Albino
- Lopes Carla
- Lopes Carla
- Lopes Elisa
- Lopes José C
- Lopes João
- Lopes Luci S
- Lopes Nuno
- Lopes Nuno V
- Lopes Nuno V
- Lopes Rui S
- Lopes Sara
- Lopes Saudade
- Loura Raquel
- Loureiro Isabel
- Loureiro Mª H
- Loureiro Mª H
- Loureiro Mª H
- Lourenço Georgina
- Lourenço Marina
- Louro Clarisse
- Louro Clarisse
- Louro Mª C
- Lousada Marisa
- Lousada Marisa
- Lousada Marisa
- Lumini José
- Luz Leonardo
- Luz Leonardo
- Luz Tatiana
- Luz Tatiana D
- Luís Henrique
- Luís Luís
- Luís Mª J
- Luís Sara
- Macedo Ana P
- Macedo António
- Macedo António
- Machado Idalina
- Machado Mª M
- Machado Patrícia O
- Machado Paulo
- Machado Paulo
- Machado Sara
- Madeira Teresa
- Madureira António
- Madureira António
- Magajewski Flávio
- Magalhães Carlos
- Magalhães Celina
- Magalhães Cátia
- Magalhães Cátia
- Magalhães Cátia
- Maia Ana S
- Maia Ana S
- Maia Ana S
- Maia Ana S
- Maia Bruno
- Maia Bruno
- Maia Carla
- Malheiro Isabel
- Malheiro Isabel
- Mangas Catarina
- Mangas Catarina
- Manso Conceição
- Manso M. C
- Marante Nídia
- Margarida Couto
- Marinho Daniel
- Marinho Sara
- Marques Alda
- Marques Alda
- Marques Alda
- Marques Alda
- Marques Alda
- Marques Alda
- Marques Alda
- Marques Alda
- Marques Alda
- Marques Ana R
- Marques António
- Marques Catarina
- Marques Cristiana
- Marques Cristiana
- Marques Daniel R
- Marques Daniel R
- Marques Fátima M
- Marques Mariana
- Marques Mariana
- Marques Mariana
- Marques Mariana
- Marques Mª F
- Marques Mário
- Marques Rita
- Marques Rita
- Marques Rita
- Marques Rita
- Marques Rita
- Marques Rita
- Marques Silvana F
- Marques Silvana F
- Marques Sílvia
- Marques Tatiana
- Marques-Rodrigues Alexandre
- Marques-Vieira Cristina
- Marquez Laura A
- Marsi Teresa O
- Marta-Simões Joana
- Marta-Simões Joana
- Marta-Simões Joana
- Marta-Simões Joana
- Martin Inmaculada Z
- Martinez-Hernandez Francisco
- Martinho Liliana
- Martins Ana R
- Martins Anabela C
- Martins Anabela C
- Martins Anabela C
- Martins Anabela C
- Martins Anabela C
- Martins Anabela C
- Martins Anabela C
- Martins Anabela C
- Martins Carlos R
- Martins Cristina
- Martins Cristina
- Martins Emília
- Martins Emília
- Martins Emília
- Martins Eveliny S
- Martins Fernando
- Martins Fátima
- Martins Julian
- Martins Laura
- Martins Maria M
- Martins Matilde
- Martins Matilde
- Martins Patrícia
- Martins Raul
- Martins Rosa
- Martín Ignácio
- Marôco João
- Marôco João
- Mata Mª A
- Mata Mª A
- Mata Mª A
- Mateus Artur
- Mateus Artur
- Matheus Filipe
- Matos Ana R
- Matos Filomena
- Matos Maria
- Matos Rui
- Medeiros Anabela
- Medeiros Dayse C
- Medeiros-Garcia Lurdes
- Medina María S
- Meireles Alexandra
- Melo Elsa
- Melo Elsa
- Melo Elsa
- Melo Flávio
- Melo Rosa
- Melo Rosa
- Melo Rosa
- Melo Rosa
- Mendes Aida
- Mendes Ana
- Mendes Ana
- Mendes Ana
- Mendes Ana L
- Mendes Ana L
- Mendes Ana L
- Mendes Elenice
- Mendes F
- Mendes F.
- Mendes Felismina
- Mendes Fernando
- Mendes Fernando
- Mendes Fernando
- Mendes Fernando
- Mendes Fernando
- Mendes Fernando
- Mendes Fernando
- Mendes Francisco
- Mendes Francisco
- Mendes Francisco
- Mendes Isabel
- Mendes Isabel
- Mendes Joana
- Mendes Maria F
- Mendes Pedro
- Mendes Pedro
- Mendes Pedro
- Mendes Pedro
- Mendes Pedro
- Mendes Pedro
- Mendes Pedro
- Mendes Romeu
- Mendes Romeu
- Mendes Romeu
- Mendes Zaida
- Mendonça Carlos
- Mendonça Nuno
- Mendonça Paula
- Mendonça Paula
- Mendonça Verónica
- Mendonça Verónica
- Meneghetti Vanize
- Meneses Rui
- Menezes Ruth L
- Menino Eva
- Menino Eva
- Menino Eva
- Menino Eva
- Mercê Cristiana
- Mesquita Helena
- Mesquita Helena
- Mesquita João R
- Midões Cristiana
- Milanés Gemma M
- Minas Bárbara
- Minghelli Beatriz
- Minghelli Beatriz
- Miranda Cristiana
- Miranda Marta
- Miranda Natacha F
- Monago Fatima M
- Monago Fatima M
- Monago Fátima M
- Monago Rocio M
- Monteiro Diogo
- Monteiro Helena
- Monteiro Joana
- Monteiro Lina
- Monteiro Luís
- Monteiro M. J
- Monteiro M. J
- Monteiro Mª J
- Monteiro Sílvia
- Morais Carminda
- Morais Marina A
- Morais Mª C
- Morais Mª C
- Morais Mª C
- Morais Mª C
- Morais Nuno
- Moreira Eliana
- Moreira Fernando
- Moreira Fernando
- Moreira Fernando
- Moreira Fernando
- Moreira Fernando
- Moreira Fernando
- Moreira Isabel
- Moreira Liliana
- Moreira Liliana
- Moreira Rita L
- Moreno Ana L
- Morgado Alice
- Morgado Sónia
- Morgado Sónia
- Morna Clementina
- Morna Clementina
- Morouço Pedro
- Morouço Pedro
- Mota Maria
- Mota Maria
- Mota Priscilla
- Moura Cynthia B
- Moura-Ramos Mariana
- Mouroço Pedro
- Mourão Ricardo
- Mártires Alice
- Mónico Lisete
- Mónico Lisete
- Mónico Lisete M
- Mónico Lisete M
- Mónico Lisete M
- Mónico Lisete M
- Mónico Lisete M
- Mónico Lisete M
- Nascimento Daniela
- Nascimento Maria S
- Nascimento V. B
- Natal Sônia
- Nave Filipe
- Nave Filipe
- Nazario Nazare
- Nazario Nazare
- Nazario Nazare
- Nazaré Cristina
- Nazário Nazaré O
- Neco Sofia
- Nelas Paula
- Neto João S
- Neves Carmo
- Neves Joana
- Neves Joel
- Neves Jéssica
- Neves Jéssica
- Neves Miguel
- Neves Sofia
- Neves Vanessa
- Nicola Paulo
- Nogueira Conceição
- Nogueira Paulo
- Nogueira Paulo
- Noné Ana
- Novais Sandra
- Novais Sandra
- Novais Sónia
- Novais Sónia
- Novo André
- Nugem Rita C
- Nugem Rita C
- Nunes Amélia
- Nunes Amélia F
- Nunes Carla
- Nunes Carla
- Nunes Carla
- Nunes Hélder
- Nunes Liliana
- Nunes S.
- Nuñez Cristina G
- Oliva Jefferson T
- Olivares Pedro R
- Oliveira Adriana
- Oliveira Ana
- Oliveira Ana
- Oliveira Ana
- Oliveira Ana I
- Oliveira Ana I
- Oliveira Ana I
- Oliveira Ana I
- Oliveira Ana I
- Oliveira Ana P
- Oliveira Anabela
- Oliveira Bibiana F
- Oliveira Bárbara
- Oliveira Camila A
- Oliveira Catarina
- Oliveira Denize C
- Oliveira Edmar S
- Oliveira Elizabete A
- Oliveira Emanuel
- Oliveira Eunice G
- Oliveira Eunice G
- Oliveira Isabel
- Oliveira Lara L
- Oliveira Manuel
- Oliveira Michelle T
- Oliveira Michelle T
- Oliveira Michelle T
- Oliveira Michelle T
- Oliveira Mirna F
- Oliveira Raul
- Oliveira Rita
- Oliveira Rita
- Oliveira Rita F
- Oliveira Rita F
- Oliveira Rita F
- Oliveira Sara
- Oliveira Sebastião T
- Oliveira Sebastião T
- Oliveira Suzete
- Oliveira Teresa C
- Oliveira Teresa T
- Oliveira Vânia P
- Olszewer Efrain O
- Ortiga Angela B
- Osório Nádia
- Osório Nádia
- Osório Nádia
- Osório Nádia
- Osório Nádia
- Pacheco José
- Padez Cristina
- Padilha José M
- Padilha José M
- Padilha José M
- Padilha José M
- Paixão S.
- Paixão Susana
- Paixão Susana
- Palmeira Lara
- Palmeira Lara
- Paraíso Nilson
- Paredes Hugo
- Parente Alexandra
- Parraça José A
- Parraça José A
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro D
- Parreira Pedro M
- Parreira Pedro M
- Parreira Pedro M
- Passadouro Rui
- Passadouro Rui
- Paulo Rui
- Paulo Rui
- Paulo Rui
- Paulo Rui
- Paulo Rui
- Paulo Rui
- Paúl Constança
- Paúl Constança
- Paúl Constança
- Pedreiro Ana
- Pedro Ana R
- Pedro Ana R
- Pedro Luísa
- Pedrosa Dora
- Pedroso Rosa
- Peixoto Ermelindo
- Peixoto-Plácido Catarina
- Peralta Teresa
- Pereira A.
- Pereira Alexandre
- Pereira Alexandre
- Pereira Ana
- Pereira Ana
- Pereira Ana
- Pereira Ana
- Pereira Ana M
- Pereira Ana M
- Pereira Ana M
- Pereira Ana T
- Pereira Ana T
- Pereira Anabela
- Pereira Carlos
- Pereira Carlos
- Pereira Carlos
- Pereira Carlos
- Pereira Carlos
- Pereira Cristina
- Pereira Elayne
- Pereira Elsa S
- Pereira Filipe
- Pereira Filomena
- Pereira Filomena
- Pereira Juliana
- Pereira Marta
- Pereira Olívia R
- Pereira Rafael
- Petrica João
- Petrica João
- Petrica João
- Petrica João
- Petrica João
- Pimenta Luís
- Pimenta Rui
- Pimentel Francisco
- Pimentel João
- Pimentel Rafaela
- Pinheiro Ana B
- Pinheiro Ana B
- Pinheiro Arminda A
- Pinheiro Patrícia C
- Pinho Cláudia
- Pinho Cláudia
- Pinho Cláudia
- Pinho Cláudia
- Pinho Cláudia
- Pinho Tânia
- Pinto Carlos
- Pinto Francisca
- Pinto Isabel C
- Pinto Isabel C
- Pinto J. L
- Pinto Joana
- Pinto M R
- Pinto Mª R
- Pinto Paulo F
- Pinto Sara
- Pinto Ítalo N
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pires Filipa
- Pires Filipa
- Pires Tânia
- Pires Tânia
- Pisco Jacinta
- Pivetta Hedioneia F
- Piñero Ana S
- Poeta Susana
- Porta-Nova Rui
- Postolache Gabriela
- Postolache Octavian
- Poço Mariana
- Prado Alessandro
- Prata Ana R
- Prebianchi Helena
- Presado Mª H
- Preto Vera
- Príncipe Fernanda
- Pulido-Fuentes Montserrat
- Pérez-Caballero Francisco L
- Pérez-Caballero Francisco L
- Queirós Paulo
- Quelhas Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Quintana-Montesdeoca Mª P
- Quirino Diogo
- Rabiais Isabel
- Rafael Helga
- Rainho Conceição
- Rainho Conceição
- Rainho Conceição
- Rama Luís
- Rama Luís
- Rama Luís
- Ramalhete Cátia
- Ramalho André
- Ramalho André
- Ramalho Fátima
- Ramalho Sónia
- Ramalho Sónia
- Ramalho Sónia A
- Ramirez Francisco B
- Ramirez Francisco B
- Ramos Maurício R
- Raposo Vítor R
- Rei Ana C
- Reina Mercedes G
- Reis Alcinda C
- Reis Ana S
- Reis Arsénio
- Reis Cláudia
- Reis Laura
- Reis Victor M
- Reses Manoela
- Reuter Éboni M
- Ribas Patrícia
- Ribeiro Andrea
- Ribeiro Andrea
- Ribeiro Diana
- Ribeiro Fernando
- Ribeiro Jaime
- Ribeiro Jaime
- Ribeiro José C
- Ribeiro João
- Ribeiro Lígia C
- Ribeiro Maria
- Ribeiro Maria
- Ribeiro Maximiano
- Ribeiro Olivério
- Ribeiro Olivério
- Ribeiro Samila G
- Ribeiro Sandra
- Ribeiro Sandra
- Ribeiro Óscar
- Ribeiro Óscar
- Ribeiro Óscar
- Ribeiro-Varandas Edna
- Richaud Sylvina
- Rocha C.
- Rocha Clara
- Rocha Clara
- Rocha Clara
- Rocha Mª C
- Rocha Mª C
- Rocha Saulo V
- Rocha Saulo V
- Rodrigo António
- Rodrigues Alexandre
- Rodrigues Alexandre
- Rodrigues Alexandrina
- Rodrigues António
- Rodrigues Cátia
- Rodrigues Diana
- Rodrigues Rogério
- Rodrigues Rogério
- Rodrigues Rogério
- Rodrigues Rosa
- Rodrigues Sandra
- Rodrigues Sandra
- Rodrigues Sandra
- Rodrigues Sandra
- Rodrigues Teresa
- Rodrigues Vítor
- Rodrigues Vítor
- Rodriguez Cláudia K
- Rodriguez-De-Vera Bienvendida C
- Rodriguez-De-Vera Bienvenida
- Rodriguez-De-Vera Bienvenida C
- Rodríguez Ana B
- Rodríguez-De-Vera Bienvenida-Del-Carmen
- Rombo João
- Roque Fátima
- Rosa Manuel S
- Rosa Marlene C
- Rosa Marlene C
- Rosa Marlene C
- Rosa Marlene C
- Rosa Marlene C
- Rosa Roger S
- Rosa Roger S
- Rosado António
- Rosado António
- Rosário Rafaela
- Ruben Rui B
- Ruivo Joana
- Saavedra Francisco
- Saboga-Nunes Luís
- Saboga-Nunes Luís
- Sala José A
- Sala José A
- Sales Tiago
- Salgueiro Anabela
- Salgueiro-Oliveira Anabela
- Salgueiro-Oliveira Anabela
- Salgueiro-Oliveira Anabela
- Salgueiro-Oliveira Anabela
- Salgueiro-Oliveira Anabela
- Salvador Mª C
- San-Martin Elisabete A
- Santana Miguel
- Santana Paula
- Santiago Conceição
- Santiago Eujcely C
- Santiago Eujcely C
- Santiago Luiz
- Santo Inês
- Santo Inês
- Santos Adriana
- Santos Ana
- Santos Bruno
- Santos Bruno
- Santos Erica
- Santos Flávia
- Santos Joana
- Santos Joana
- Santos Jorge
- Santos João
- Santos Leonino S
- Santos Luísa
- Santos Marina S
- Santos Marlene
- Santos Marlene
- Santos Nuno
- Santos Osvaldo
- Santos Osvaldo
- Santos Osvaldo
- Santos Rafael B
- Santos Rafael B
- Santos Sofia
- Santos Sofia
- Santos Sofia
- Santos Sofia
- Santos-Rocha Rita
- Sardo Dolores
- Sardo Pedro
- Sardo Pedro
- Sarmento-Ribeiro Ana B
- Sarreira-Santos Alexandra
- Sarroeira Cassilda
- Schneider Dulcineia
- Schneider Dulcineia
- Schneiders Paloma B
- Schroeder Silvana S
- Schukg Susann
- Seabra André
- Seabra Daniel
- Seabra Daniel
- Seabra Paulo
- Seixas Adérito
- Seixas Adérito
- Seixas Adérito
- Seixas Adérito
- Seiça Luís
- Seppänen Ulla-Maija
- Serapioni Mauro
- Serra Ana
- Serrano João
- Serrano João
- Serrano João
- Serrano João
- Serrano João
- Severino Sandy
- Siba Wafa A
- Silva Ana M
- Silva Ana M
- Silva Andrea G
- Silva André
- Silva Antónia
- Silva Armando
- Silva Carina
- Silva Carla R
- Silva Carlos
- Silva Carlos F
- Silva Catarina
- Silva Cláudia
- Silva Cláudia D
- Silva Daniel
- Silva Daniel
- Silva Darlen
- Silva David
- Silva Eduardo
- Silva Elsa
- Silva Ernestina
- Silva Helena R
- Silva Helena R
- Silva Iryna
- Silva Isabel
- Silva Joana
- Silva Joana
- Silva Joana
- Silva Luís D
- Silva Luís D
- Silva Maiza M
- Silva Manuel C
- Silva Margarida
- Silva Margarida
- Silva Maria A
- Silva Marilene
- Silva Marilene
- Silva Norberto
- Silva Paula
- Silva Paula A
- Silva Pedro
- Silva Pedro
- Silva Rafael
- Silva Rita
- Silva Rita
- Silva Rita P
- Silva Sara
- Silva Sara
- Silva Sara
- Silva Susana
- Silva Tatiane M
- Silva Vânia
- Silveira Paulo
- Sim-Sim Margarida
- Simões Alexandra
- Simões Cristina
- Simões João
- Simões Paulo C
- Simões Sónia
- Simões Ângela
- Siqueira Mariana S
- Siqueira Mariana S
- Soar Cláudia
- Soares Célia
- Soares Fátima
- Soares Fátima
- Soares Raquel
- Soares Salete
- Soares Sérgio
- Soares Valter
- Sousa Ana P
- Sousa Ana S
- Sousa Anderson R
- Sousa Anderson R
- Sousa Anderson R
- Sousa Anderson R
- Sousa Carla
- Sousa Caroline R
- Sousa Cesar
- Sousa D.
- Sousa Diana
- Sousa Gilberta
- Sousa Gilberta
- Sousa Gracinda
- Sousa Jani
- Sousa Joana
- Sousa Joana
- Sousa Luís
- Sousa Marina
- Sousa Marina
- Sousa Nelson
- Sousa Nelson
- Sousa Patrícia
- Sousa Patrícia
- Sousa Patrícia
- Sousa Patrícia
- Sousa Patrícia
- Sousa Patrícia
- Sousa Paulino
- Sousa Paulino
- Sousa Paulino
- Sousa Paulino
- Sousa Pedro
- Sousa Pedro
- Sousa Pedro
- Sousa Pedro
- Sousa Pedro
- Souza Clóvis A
- Souza Géssica M
- Souza Juliana A
- Souza Nelba R
- Souza Nelba R
- Spolaôr Newton
- Svensson Lola
- Sá Dayse
- Tapadas Rodrigo
- Tavares Aida I
- Tavares Ana
- Tavares Ana S
- Tavares José
- Tavares Mariline
- Tavares Nuno
- Teixeira A.
- Teixeira Ana
- Teixeira Ana
- Teixeira Ana M
- Teixeira Laetitia
- Teixo Ricardo
- Teles Patrícia
- Tena José M
- Tena Maria J
- Tenedório José A
- Tim-Tim Carolina
- Tomaz Jorge
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina C
- Tomás Teresa
- Topa Joana
- Torgal Jorge
- Torgal Jorge
- Torres Ana
- Torres Rui
- Trigo Africa P
- Trindade Inês A
- Trindade Inês A
- Trindade Inês A
- Trindade Inês A
- Tuna Ana R
- Tytgat Ite
- Uba-Chupel M.
- Uba-Chupel Mateus
- Ugalde Lierni U
- Ugartemendia Lierni
- Valado Ana
- Valado Ana
- Valado Ana
- Valado Ana
- Valado Ana
- Vale-Dias Luz
- Vale-Dias Maria L
- Valente Ana R
- Valente Carolina
- Valente Jorge
- Valente João
- Valim Frederico C
- Valim Frederico C
- Vaquinhas Marina
- Vaquinhas Marina
- Vaquinhas Marina
- Vaquinhas Marina
- Varandas Edna
- Vardasca Ricardo
- Vardasca Ricardo
- Vasconcelos Carlos
- Vasconcelos Carlos
- Vasconcelos Lélia R
- Vasconcelos Rita
- Vasconcelos Rita
- Vaz Daniela C
- Vaz Josiana A
- Vehreschild Viktor
- Vehreschild Viktor
- Veiga Nélio
- Veiga Nélio
- Veiga Nélio
- Veiga Nélio
- Veiga-Branco Mª
- Velosa Fábia
- Veloso Milene
- Ventura David
- Ventura Maria
- Ventura Rita
- Ventura Sandra
- Vicente Corália
- Vicente Corália
- Vicente Corália
- Vicente Sara
- Vicente Sónia
- Vidal Eglidia F
- Viega-Branco Maria
- Vieira André
- Vieira Margarida
- Vieira Viviane L
- Vieitez Juan G
- Villanueva Ana G
- Vincha Kellem R
- Vinha Ana F
- Virgolino Ana
- Vizzotto Betina P
- Vélez Marta M
- Welter Aline
- Xavier Ana
- Xavier Ana
- Xavier Sandra
- Xavier Sandra
- Zilhão Adriano
- Publication venue
- Publication date
- 01/01/2004
- Field of study
As part of an EU funded project to investigate the factors influencing bone preservation in the archaeological record, more than 250 bones from 41 archaeological sites in five countries spanning four climatic regions were studied for diagenetic alteration. Sites were selected to cover a range of environmental conditions and archaeological contexts. Microscopic and physical (mercury intrusion porosimetry) analyses of these bones revealed that the majority (68%) had suffered microbial attack. Furthermore, significant differences were found between animal and human bone in both the state of preservation and the type of microbial attack present. These differences in preservation might result from differences in early taphonomy of the bones. © 2003 Elsevier Science Ltd. All rights reserved
Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries
- Author
- Aarts Frits
- Ababneh Hazim
- Abad-Motos Ane
- Abaidalla Ahmed
- Abbakar Malaz
- Abd El Aal Ahmed
- Abd-Errazik Mohammad Ahmad
- Abdalradiy Abdalrahmman G
- Abdelkhalek Mohamed
- Abdelkhalek Mostafa
- Abdellatif Ahmed
- Abdellatif Mohamed
- Abdelsaid Kirolas
- Abdou Khaled
- Abdulfatah Mustapha
- Abdullah Mohammad Amer
- Abdullahi Mustapha Miko Mohammed
- Abellán Antonio Melero
- Abeysinghe Nayana
- Abiyere Henry
- Achimas-Cadariu Patriciu Andrei
- Adakaya Sıla
- Adam Nicolas
- Adams Benita
- Adams Ferdinand
- Adegboye Kazeem
- Adeyeye Ademola
- Adra Lama
- Adu-Poku Patricia
- Afuwape Oludolapo
- Afzal Ameer
- Afzal Muhammad Farooq
- Agapov Mihail
- Agara Daniel
- Aggarwal Manisha
- Agger Erika
- Aghadi Ifeanyi Kene
- Ahmed Amjed Yassir
- Ahmed Haleemasahdia
- Ahmed Khalil
- Ahmed Manar
- Ahmed Masood
- Ahmed Safia
- Ahn Hong Min
- Aibe Raquel
- Aigner Felix
- Aissat Abdenour
- Aitbaeva Arai
- Akay Omer
- Akbar Ali
- Akbas Ahmet
- Akere Abidemi
- Akesen Selcan
- Akgun Erhan
- Akhtar Naseem
- Akın Emrah
- Akova Elif
- Aktas Serhat
- Akçay Özlem
- Al Masri Mahmoud
- Al-Alnsi Ahmed
- Al-Hutheifi Roqia'A
- Al-Jarrah Amar
- Al-Naggar Hamza
- Al-Shehari Mohammed
- Alamin Nadeen
- Alawi Raneen
- Alawlaqi Dina
- Alawneh Fade
- Alberola Maria José
- Albers Michael
- Alcolea Natalia González
- Aleem Muhammad
- Alegre Inês
- Alegre Javier Martinez
- Alexandre Flavia
- Alexandrescu Corina
- Alexnder Abelevich
- Alexopoulou Kalliopi
- Alfonso Beatriz Amorós
- Ali Ahmed
- Ali Che Saniati Che
- Ali Danish
- Ali Madeeha
- Ali Mahmoud Abdelwahab
- Ali Manhal Hashim
- Ali Noura Al
- Alikhanli Jhale
- Aliyeva Zumrud
- Aliyu Mohammed
- Aljawder Hasan
- Allen Kate
- Almahmeed Ebrahim
- Alonso Alfredo
- Alonso Javier Etreros
- Alsamneh Muneer
- Alsayadi Ramzi
- Altinel Yuksel
- Altintoprak Fatih
- Altomare Donato F
- Alvarenga Isabella
- Alvarez Laura Jimenez
- Alvarez-Bautista Francisco Emmanuel
- Alvarez-Díez Marcos
- Alves Brenda Chayanny
- Amadigwe Rita
- Amado Andreia
- Amado Fabíola
- Amador Cristina García
- Amanullah Nazli
- Amaral Hélida Aline Tomacheski
- Amaral Luis
- Amin-Tai Hizami
- Aminu Bashiru
- Amir Ahmad Suhaimi
- Ammar Ahmed Siddique
- Ammar Mona Ahmed
- Ammendola Michele
- Ammerata Giorgio
- Amorim Edgar
- Ancans Guntis
- Anderson Tom
- Andrade Diogo
- Andrejevic Predrag
- Andrés Beatriz Díaz San
- Anestiadou Elissavet
- Ang Chin Wee
- Angelo Franceschi
- Anokhin Evgeny
- Anoldo Pietro
- Antakia Ramez
- Anton Majd
- Antonelli Serena
- Antropoli Carmine
- Anula Rocio
- Anwar Jamal
- Anyadike Florence
- Apostolakidou Magda
- Apostolidi Eirini
- Aprea Giovanni
- Arabadzhiev Angel
- Arakawa Satoshi
- Arauz Jazmin
- Aravindan U
- Aremu Abdurrahman
- Aremu Isiaka
- Argawy Osama
- Arican Can
- Arida Zahed Abu
- Armellin Claudia
- Arnaoutoglou Eleni
- Arreguy-Borges Kanthya
- Artigot Mariano
- Arturi Alessandro
- Arulappan Nirupama
- Arya Shobhit
- Arynov Ardak
- Asaad Peter
- Asano Yukio
- Ascari Francesca
- Asgarov Mohsum
- Ashmawy Soad
- Aslam Muhammad Imran
- Assimakopoulou Elena
- Assis Ana
- Astilleta Romina
- Atanasov Boyko
- Atendido Tiffany
- Athanasakis Elias
- Atici Semra Demirli
- Avellaneda Nicholas
- Avellaneda Nicolas
- Avseren Goksu
- Awead Marwa
- Ayandipo Omobolaji
- Aybar Engin
- Aydin Funda
- Aydin Gaye
- Ayoub Kusay
- Aytac Erman
- Aytaç Erman
- Azevedo Jose
- Azevedo Patricia
- Azhar Najia
- Aziz Gowhar
- Azman Zairul Azwan Mohd
- Aşkar Ahmet
- Babatunde Olanrewaju
- Badawi Marwa
- Baek Jeong-Heum
- Baez Noelia Fernández
- Baeza-Murcia Melody
- Bagnardi Francesco
- Baharom Salahudin
- Baik Seung Hyuk
- Baimakhanov Abylai
- Bains Lovenish
- Baker Aleksandra
- Bakmaz Bernarda
- Bala Abubakar Muhammad
- Balaban Vladimir
- Balalis Dimitrios
- Balasubramaniam Dinesh
- Balathayalan Yathev
- Baldi Claudio
- Balestri Riccardo
- Balfour James
- Ballah Abubakar
- Ballian Nikiforos
- Balooshi Iman Al
- Baloyiannis Ioannis
- Bamford Richard
- Bandar Mahdi Al
- Banham Gail
- Bannoud Mohammad Hassan
- Baptista Victor
- Baral Jörg
- Barbalace Nicolas
- Barbato Giuseppe
- Barbosa Anderson
- Bareka Metaxia
- Baris Baver
- Barradas Renato
- Barreda Sara Castillo
- Barrena-Blazquez Silvestra
- Barton Jess
- Bartosiak Katarzyna
- Bashilkina Olga
- Bashir Mohammed
- Basile Raffaele
- Basnyat Pradeep
- Batool Sana
- Bautista Wilson Manuel Sánchez
- Bayhan Zülfü
- Bayo José Manuel Muros
- Bayón Raquel Álvaro
- Baños Pedro Antonio Parra
- Beard David
- Bedzhanyan Arkady
- Behilil Chakib
- Bekele Kebebe
- Belarmino Armin
- Belay Million
- Belev Nikolay
- Bellato Vittoria
- Beltrán de Heredia Juan
- Belvedere Angela
- Benetti Emilio
- Benetti Sara
- Bengueddach Aicha
- Benjelloun El Bachir
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- Yılmaz Gülseren
- Yilmazlar Tuncay
- Yiğit Direnç
- Yoldas Tayfun
- Yonekura Hiroshi
- Yorkmui Liu
- Yoshino Kenji
- Younes Lina
- Young Trudi
- Yule Michael
- Yusoff Zakiah Mohd
- Zaari Fatimazahraa
- Zabiyaka Mikhail
- Zadrożna Monika
- Zafar Madiha
- Zagaynov Eugeny
- Zaidi Syed-Nadeem
- Zaimis Tilemachos
- Zain Wan Zainira Wan
- Zainy Rhendra Hardy Mohamad
- Zakaria Andee Dzulkarnaen
- Zakaria Maheen
- Zakaria Zaidi
- Zamudio-Bautista Jorge Luis
- Zanc Loredana
- Zanoni Andrea
- Zanus Giacomo
- Zapparoli Alessandro
- Zappone Anna
- Zarzava Eirini
- Zatari Dirar
- Zawadzki Marek
- Zayakov Georgi
- Zaycev Andrey
- Zazo Aya
- Zazo Rama
- Zdravkovic Maja
- Zengin Abdullah Kağan
- Zeringa Georgia
- Zimmerman David D E
- Zuhdy Mohammad
- Zvirych Vitalii
- Zywicka Ewa
- Álvarez-Llano Laura
- Ângelo Miguel Duarte
- ÓSullivan Sara Nuñez
- Özçelik Mehmet Faik
- Ćoza Ivo
- Şanlı Ahmet Necati
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Background
Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks.
Methods
The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an online educational module introducing risk stratification, an intraoperative checklist, and harmonized surgical techniques. Clusters (hospital teams) were randomized to one of three arms with varied sequences of intervention/data collection by a derived stepped-wedge batch design (at least 18 hospital teams per batch). Patients were blinded to the study allocation. Low- and middle-income country enrolment was encouraged. The primary outcome (assessed by intention to treat) was anastomotic leak rate, and subgroup analyses by module completion (at least 80 per cent of surgeons, high engagement; less than 50 per cent, low engagement) were preplanned.
Results
A total 355 hospital teams registered, with 332 from 64 countries (39.2 per cent low and middle income) included in the final analysis. The online modules were completed by half of the surgeons (2143 of 4411). The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1.30; P = 0.498). The proportion of surgeons completing the educational modules was an influence: the leak rate decreased from 12.2 per cent (61 of 500) before intervention to 5.1 per cent (24 of 473) after intervention in high-engagement centres (adjusted OR 0.36, 0.20 to 0.64; P < 0.001), but this was not observed in low-engagement hospitals (8.3 per cent (59 of 714) and 13.8 per cent (61 of 443) respectively; adjusted OR 2.09, 1.31 to 3.31).
Conclusion
Completion of globally available digital training by engaged teams can alter anastomotic leak rates. Registration number: NCT04270721 (http://www.clinicaltrials.gov)
Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study
- Author
- Abe Toshikazu
- Aboshady Abdelrhman
- Abrough Fekri
- Acampo-de Jong Melanie
- Acharya Subhash
- Acharya Subhash P
- Adderley Jane
- Adiguzel Nalan
- Agrawal Vijay Kumar
- Aguilar Gerardo
- Aguirre Gaston
- Aguirre-Bermeo Hernan
- Ahlström Björn
- Akbas Türkay
- Akker Mustafa
- Al Sadeh Ghamdan
- Alamri Sultan
- Algaba Angela
- Ali Muneeb
- Aliberti Anna
- Allegue Jose Manuel
- Alvarez Diana
- Amador Joaquin
- Amin Pravin
- Andersen Finn H
- Ansari Sharique
- Apichatbutr Yutthana
- Apostolopoulou Olympia
- Arabi Yaseen
- Arabi Yaseen
- Aragao Irene
- Aragao Irene
- Arellano Daniel
- Arica Mestanza
- Arikan Huseyin
- Arinaga Koichi
- Arnal Jean-Michel
- Asano Kengo
- Asín-Corrochano Marta
- Avalos Cabrera Jesus Milagrito
- Avila Fuentes Silvia
- Aydemir Semih
- Aygencel Gulbin
- Azevedo Luciano
- Bacakoglu Feza
- Badie Julio
- Baedorf Kassis Elias
- Bai Gabriela
- Balaraj Govindan
- Ballico Bruno
- Banner-Goodspeed Valerie
- Banwarie Preveen
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- Barrueco-Francioni Jesus Emilio
- Barry Jeffrey
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- Bauer Philippe
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- Beduneau Gaëtan
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- Beitler Jeremy
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- Zhu Bin
- Zumaran Ronald
- Çukurova Zafer
- Öveges Nándo
- Özyilmaz Ezgi
- Publication venue
- 'Elsevier BV'
- Publication date
- 21/01/2023
- Field of study
Background
Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients requiring at least 2 days of invasive mechanical ventilation.
Methods
WEAN SAFE was an international, multicentre, prospective, observational cohort study done in 481 intensive care units in 50 countries. Eligible participants were older than 16 years, admitted to a participating intensive care unit, and receiving mechanical ventilation for 2 calendar days or longer. We defined weaning initiation as the first attempt to separate a patient from the ventilator, successful weaning as no reintubation or death within 7 days of extubation, and weaning eligibility criteria based on positive end-expiratory pressure, fractional concentration of oxygen in inspired air, and vasopressors. The primary outcome was the proportion of patients successfully weaned at 90 days. Key secondary outcomes included weaning duration, timing of weaning events, factors associated with weaning delay and weaning failure, and hospital outcomes. This study is registered with ClinicalTrials.gov, NCT03255109.
Findings
Between Oct 4, 2017, and June 25, 2018, 10 232 patients were screened for eligibility, of whom 5869 were enrolled. 4523 (77·1%) patients underwent at least one separation attempt and 3817 (65·0%) patients were successfully weaned from ventilation at day 90. 237 (4·0%) patients were transferred before any separation attempt, 153 (2·6%) were transferred after at least one separation attempt and not successfully weaned, and 1662 (28·3%) died while invasively ventilated. The median time from fulfilling weaning eligibility criteria to first separation attempt was 1 day (IQR 0–4), and 1013 (22·4%) patients had a delay in initiating first separation of 5 or more days. Of the 4523 (77·1%) patients with separation attempts, 2927 (64·7%) had a short wean (≤1 day), 457 (10·1%) had intermediate weaning (2–6 days), 433 (9·6%) required prolonged weaning (≥7 days), and 706 (15·6%) had weaning failure. Higher sedation scores were independently associated with delayed initiation of weaning. Delayed initiation of weaning and higher sedation scores were independently associated with weaning failure. 1742 (31·8%) of 5479 patients died in the intensive care unit and 2095 (38·3%) of 5465 patients died in hospital.
Interpretation
In critically ill patients receiving at least 2 days of invasive mechanical ventilation, only 65% were weaned at 90 days. A better understanding of factors that delay the weaning process, such as delays in weaning initiation or excessive sedation levels, might improve weaning success rates
Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study
- Author
- Abdelhamid Hachimi
- Abdellatif Benslama
- Abdelrhman Aboshady
- Abhijit Duggal
- Abidi Khalid
- Abubaker S Elmaryul
- Adela Benitez-Cano
- Adi Hadzibegovic
- Adrian Regli
- Agnes Sarkany
- Agnieszka Kubisz-Pudelko
- Agrippino Bellissima
- Agueda Ojados
- Ahmad Zaki
- Ahmed Rabie
- Aikaterini Dimoula
- Aiman Tulaimat
- Aitor Olmos
- Akihiro Takaba
- Akira Kuriyama
- Akram Khan
- Alastair Rose
- Alberto Belenguer Muncharaz
- Alberto Deicas
- Alberto Facchini
- Aldana Ruiz Robledo
- Alejandro Esquivel
- Alejandro Gonzalez-Castro
- Alejandro Risso Vazquez
- Alejandro Ubeda
- Alessandra Nasi
- Alex Martin
- Alexandre Molin
- Alexandre Tonnelier
- Alexey Gritsan
- Alexey Gritsan
- Alexis Jaspe Codecido
- Alfred Papali
- Alisha Van Axel
- Alistair Nichol
- Alma Cani
- Ameet Parekh
- Amine Ali Zeggwagh
- Amira Jamoussi
- Amy Collins
- Ana Raquel Lima
- Ana Vaz
- Ana Villagra
- Ana Vochin
- Anahita Rouze
- Anaid Manzano
- Analía Garcia
- Anand Thakur
- Anatilde Diaz
- Andrea Bruni
- Andrea Coppadoro
- Andrea Cortegiani
- Andrea Gabriela Peña Padilla
- Andrea Gigante
- Andrea Neville Cracchiolo
- Andrew Bersten
- Andrew Hermon
- Andrew McKown
- Andrew Seely
- Andrew Stapleton
- Andrey Gazenkampf
- Andrey Malyarchikov
- Angela Algaba
- Angela Rogers
- Angelo Giacomucci
- Angus Richardson
- Anil Hormis
- Anna Aliberti
- Anna Mattsson
- Antoinette Wilson
- Antonella Fortunato
- Antonella Frattari
- Antonia Vazquez-Sanchez
- Antonio Castelli
- Antonio Landaverde Lopez
- Antonio Luis Ruiz-Aguilar
- Anxela Vidal
- Aragao Irene
- Arantxa Mas
- Ariel Chena
- Arif Moghal
- Arnaud W Thille
- Aroa Gomez
- Arturo Briva
- Arvind Baronia
- Ary Serpa Neto
- Ary Serpa Neto
- Arzu Esen Tekeli
- Ashish K Khanna
- Ashish Rai
- Asim Shah
- Asisclo Villagomez
- Asisclo Villagomez
- Asma Ben Souissi
- Assem Abdel Razek
- Aude Garnero
- Aurélie Joret
- Avsar Zerman
- Ayca Gumus
- Ayse Nur Soyturk
- Banambar Ray
- Basanta Kumar Pati
- Beatriz Llorente
- Beduneau Gaëtan
- Begoña Zalba-Etayo
- Bellani Giacomo
- Benjamin Delmas
- Bernardo Panka
- Bernardo Panka
- Bernie Bissett
- Bertrand Sauneuf
- Betania Silva Sales
- Betty Tsuei
- Bhagyesh Shah
- Bi-Lin Wei
- Bin Zang
- Bin Zhu
- Björn Ahlström
- Bo Young Lee
- Bojan Jovanovic
- Bojan Jovanovic
- Borja Fernandez
- Boyun Yuan
- Brahim Housni
- Branislava Stefanovic
- Brit Ågot Sjøbø
- Brochard Laurent
- Bror Anders Johnstad
- Bruno Ballico
- Bruno Vilela Costa Pinto
- Candelaria de Haro
- Carla Santos
- Carlo Alberto Volta
- Carlo Oliveri
- Carlos Ferrando
- Carlos Munoz de Cabo
- Carlos Pellegrini
- Carmel Chapman
- Carmen Hernandez
- Caroline Kane
- Catalina Forteza
- Catherine Motherway
- Cecilia Eugenia Chavez
- Cenk Kirakli
- Ceri Lynch
- Cesar Perez Calvo
- Chen Jing
- Chen Shuhua
- Chengqing Mei
- Chenliang Sun
- Cherdkiat Karnjanarachata
- Christian Tomaszewski
- Christine M Bojanowski
- Christopher Tainter
- Christopher Wright
- Christos Chaintoutis
- Chrysi Diakaki
- Chuanyun Qian
- Clare Hammel
- Claude Guérin
- Claudia Elizabeth Lopez
- Claudia Lopez Nava
- Claudio Piras
- Colin Grissom
- Conchita Martínez-Fidalgo
- Cosimo Chelazzi
- Covadonga Rodriguez
- Cristina Coxo
- Cristina Martin Dal Gesso
- Cristina Villegas Succar
- Csaba Kopitko
- Cédric Bruel
- Cédric Daubin
- César Laborda
- Dagmar Holmquist
- Dahuan Li
- Daisuke Taniguchi
- Damien Roux
- Dan Lind
- Dana Tomescu
- Daniel Arellano
- Daniel Horner
- Daniel Moreno Torres
- Daniel Paul
- Daniel Rodriguez Gonzalez
- Daniel Silva
- Daniel Talmor
- Daniela Benvenuti
- Darshana Rathod
- David Blythe
- David Carpio
- David Dries
- David Perez-Torres
- David Slessor
- David Wrathall
- Davide Chiumello
- Deborah Welsh
- Deepak Jeswani
- Demetrio Carriedo
- Detajin Junhasavasdikul
- Diana Alvarez
- Dianne Hill
- Dick Nahar
- Didem Sozutek
- Diego De Mendoza
- Diego Rolando Morocho Tutillo
- Dieneke Kienhorst
- Dimitrios Matamis
- Dina Gomaa
- Dolf Weller
- Domenico Gelormini
- Don Walsh
- Doumiri Mouhssine
- Dácil Parrilla
- Edoardo Picetti
- Edoardo Piervincenzi
- Eduardo Beck
- Eduardo Labarca
- Edward Fysh
- Edward Litton
- Ege Eroglu
- Elena Nikolic
- Eleni Massa
- Eleni Mouloudi
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- Eliana Markman
- Elias Baedorf Kassis
- Elif Erdogan
- Elisa Boni
- Elisa Estenssoro
- Elisa Kam
- Elisabet Garcia
- Elisabeth Surlemont
- Elisabetta Pecci
- Elisabetta Pierucci
- Elizabeth Ramey
- Elizabeth Stevenson
- Elizabeth Wilby
- Elliot Bertram-Ralph
- Elliot Yates
- Elsa Sousa
- Eman Shebl
- Emanuele Sani
- Emilio Maseda
- Emmanuel Guerot
- Enrique Cereijo
- Enrique Paz
- Enrique Platas
- Eric Frans
- Erin Williams
- Estefania Prol-Silva
- Etienne Ghrenassia
- Ettore Vascotto
- Eugenio Garofalo
- Eugenio Luis Palazon Sanchez
- Ewan Goligher
- Ezgi Ozyilmaz
- Ezgi Özyilmaz
- Fabianne Dantas
- Fabio Guarracino
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- Faruk Seçkin Yücesoy
- Fatma Yildirim
- Faustine Reynaud
- Federica Vagginelli
- Federico Gordo
- Fekri Abrough
- Felipe de Jesus Montelongo
- Felipe Martinez
- Felix Martin
- Feng Feng
- Fernanda Kutchak
- Fernando da Silva Ramos
- Fernando Pachas Alvarado
- Fernando Rios
- Fernando Rios
- Ferran Roche-Campo
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- Feza Bacakoglu
- Figen Esen
- Filiep Soetens
- Finn H Andersen
- Francesca Lucchese
- Francesca Orsenigo
- Francesco Curto
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- Frank Chemouni
- Frank Van Haren
- Frank Van Haren
- François Philippart
- Françoise Labat
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- Frédérique Schortgen
- Gabriel Omar Heredia Orbegoso
- Gabriel Preda
- Gabriel Rodriguez
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- Gabriele Sales
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- Gemma Rialp
- Gennaro De Pascale
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- Ghamdan Al Sadeh
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- Giacomo Grasselli
- Gianluca Zani
- Gianmario Monza
- Gilda Cinnella
- Giorgio Antonio Iotti
- Giovanna Soto
- Giovanni Mistraletti
- Giovanni Vitale
- Goligher Ewan C
- Gong Yu
- Gonzalo Pagella
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- Graciela Paz
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- Graeme Duke
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- Guillaume Voiriot
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- Guillermo Bugedo
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- Gulbin Aygencel
- Guo Xi
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- Guoxiu Zhang
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- Gustavogcha Chaparro
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- Harshal Bawangade
- Hector Higo Leon Yoshido
- Helbert Esquivel Gallegos
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- Hongping Qu
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- Kevin Clarkson
- Kevin Eng
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- Konstanty Szuldrzynski
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- Kyung Sook Hong
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- Xiaobo Yang
- Xie Yun
- Yalim Dikmen
- Yari Gollo
- Yaseen Arabi
- Yaseen Arabi
- Yasemin Seker Tekdos
- Yazcitk Sandoval
- You Shang
- Youjin Chang
- Young Ju Lee
- Young-Jae Cho
- Young-Jae Cho
- Yuda Sutherasan
- Yufeng Feng
- Yukako Obata
- Yupeng Qi
- Yutthana Apichatbutr
- Yvette Chou-Lie
- Zafer Çukurova
- Zhang Minwei
- Zhanhong Tang
- Zheng-Jiang Xing
- Zhenglong Ye
- Zoltan Kulcsar
- Zsolt Molnar
- Zsolt Molnar
- Zsuzsanna Szabo
- Óscar Peñuelas
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2023
- Field of study
Background: Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients requiring at least 2 days of invasive mechanical ventilation. Methods: WEAN SAFE was an international, multicentre, prospective, observational cohort study done in 481 intensive care units in 50 countries. Eligible participants were older than 16 years, admitted to a participating intensive care unit, and receiving mechanical ventilation for 2 calendar days or longer. We defined weaning initiation as the first attempt to separate a patient from the ventilator, successful weaning as no reintubation or death within 7 days of extubation, and weaning eligibility criteria based on positive end-expiratory pressure, fractional concentration of oxygen in inspired air, and vasopressors. The primary outcome was the proportion of patients successfully weaned at 90 days. Key secondary outcomes included weaning duration, timing of weaning events, factors associated with weaning delay and weaning failure, and hospital outcomes. This study is registered with ClinicalTrials.gov, NCT03255109. Findings: Between Oct 4, 2017, and June 25, 2018, 10 232 patients were screened for eligibility, of whom 5869 were enrolled. 4523 (77·1%) patients underwent at least one separation attempt and 3817 (65·0%) patients were successfully weaned from ventilation at day 90. 237 (4·0%) patients were transferred before any separation attempt, 153 (2·6%) were transferred after at least one separation attempt and not successfully weaned, and 1662 (28·3%) died while invasively ventilated. The median time from fulfilling weaning eligibility criteria to first separation attempt was 1 day (IQR 0-4), and 1013 (22·4%) patients had a delay in initiating first separation of 5 or more days. Of the 4523 (77·1%) patients with separation attempts, 2927 (64·7%) had a short wean (≤1 day), 457 (10·1%) had intermediate weaning (2-6 days), 433 (9·6%) required prolonged weaning (≥7 days), and 706 (15·6%) had weaning failure. Higher sedation scores were independently associated with delayed initiation of weaning. Delayed initiation of weaning and higher sedation scores were independently associated with weaning failure. 1742 (31·8%) of 5479 patients died in the intensive care unit and 2095 (38·3%) of 5465 patients died in hospital. Interpretation: In critically ill patients receiving at least 2 days of invasive mechanical ventilation, only 65% were weaned at 90 days. A better understanding of factors that delay the weaning process, such as delays in weaning initiation or excessive sedation levels, might improve weaning success rates. Funding: European Society of Intensive Care Medicine, European Respiratory Society
Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study
- Author
- Abe T.
- Aboshady Abdelrhman
- Abrough Fekri
- Acampo-de Jong Melanie J.
- Acharya S.
- Acharya Subhash P.
- Adderley Jane
- Adiguzel N.
- Agrawal V.K.
- Aguilar G.
- Aguirre Gaston
- Aguirre-Bermeo Hernán
- Ahlström B.
- Akbas Türkay
- Akker M.
- Al Sadeh G.
- Alamri S.
- Algaba Ángela
- Ali M.
- Aliberti A.
- Allegue J.M.
- Alvarez Diana
- Amador J.
- Amin P.
- Andersen F.H.
- Ansari S.
- Apichatbutr Yutthana
- Apostolopoulou Olympia
- Arabi Y.
- Aragao Irene César
- Arellano D.
- Arica Mestanza
- Arikan Huseyin
- Arinaga K.
- Arnal J.-M.
- Asano Kengo
- Asín-Corrochano M.
- Avalos Cabrera J.M.
- Avila Fuentes S.
- Aydemir Semih
- Aygencel Gulbin
- Azevedo L.
- Bacakoglu Feza
- Badie Julio C.
- Baedorf Kassis E.
- Bai Gabriela
- Balaraj Govindan
- Ballico B.
- Banner-Goodspeed Valerie M.
- Banwarie Preveen
- Barbieri R.
- Baronia Arvind Kumar
- Barrett Jonathan A.
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- Barrueco-Francioni Jesus Emilio
- Barry Jeffrey
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- Wunsch H.
- Xi Guo
- Xing Zhengjiang
- Xu H.
- Yamamoto K.
- Yan Jie
- Yang X.
- Yates E.
- Yazicioglu Mocin Özlem
- Ye Zhenglong
- Yildirim F.
- Yoshida Norifumi
- Yoshido Hector Higo Leon
- Young Lee B.
- Yu Gong
- Yu R.
- Yu T.
- Yuan B.
- Yuangtrakul N.
- Yumoto Tetsuya
- Yun Xie
- Yáñez J.
- Zakalik G.
- Zaki Ahmed
- Zalba-Etayo Begoña
- Zambon Massimo
- Zang Bin
- Zani G.
- Zarka Jonathan
- Zeggwagh A.A.
- Zerbi S.M.
- Zerman A.
- Zetterquist H.
- Zhang Guoxiu
- Zhang Hongwen
- Zhang Jiuzhi
- Zhang W.
- Zhang Weixin
- Zhao H.
- Zheng Jia
- Zhu Bin
- Zumaran R.
- Çukurova Z.
- Öveges Nándo
- Publication venue
- Elsevier
- Publication date
- 01/01/2023
- Field of study
International audienceBackground: Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients requiring at least 2 days of invasive mechanical ventilation. Methods: WEAN SAFE was an international, multicentre, prospective, observational cohort study done in 481 intensive care units in 50 countries. Eligible participants were older than 16 years, admitted to a participating intensive care unit, and receiving mechanical ventilation for 2 calendar days or longer. We defined weaning initiation as the first attempt to separate a patient from the ventilator, successful weaning as no reintubation or death within 7 days of extubation, and weaning eligibility criteria based on positive end-expiratory pressure, fractional concentration of oxygen in inspired air, and vasopressors. The primary outcome was the proportion of patients successfully weaned at 90 days. Key secondary outcomes included weaning duration, timing of weaning events, factors associated with weaning delay and weaning failure, and hospital outcomes. This study is registered with ClinicalTrials.gov, NCT03255109. Findings: Between Oct 4, 2017, and June 25, 2018, 10 232 patients were screened for eligibility, of whom 5869 were enrolled. 4523 (77·1%) patients underwent at least one separation attempt and 3817 (65·0%) patients were successfully weaned from ventilation at day 90. 237 (4·0%) patients were transferred before any separation attempt, 153 (2·6%) were transferred after at least one separation attempt and not successfully weaned, and 1662 (28·3%) died while invasively ventilated. The median time from fulfilling weaning eligibility criteria to first separation attempt was 1 day (IQR 0–4), and 1013 (22·4%) patients had a delay in initiating first separation of 5 or more days. Of the 4523 (77·1%) patients with separation attempts, 2927 (64·7%) had a short wean (≤1 day), 457 (10·1%) had intermediate weaning (2–6 days), 433 (9·6%) required prolonged weaning (≥7 days), and 706 (15·6%) had weaning failure. Higher sedation scores were independently associated with delayed initiation of weaning. Delayed initiation of weaning and higher sedation scores were independently associated with weaning failure. 1742 (31·8%) of 5479 patients died in the intensive care unit and 2095 (38·3%) of 5465 patients died in hospital. Interpretation: In critically ill patients receiving at least 2 days of invasive mechanical ventilation, only 65% were weaned at 90 days. A better understanding of factors that delay the weaning process, such as delays in weaning initiation or excessive sedation levels, might improve weaning success rates. Funding: European Society of Intensive Care Medicine, European Respiratory Society
Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
- Abdullayev Seymur
- Abed Saeed
- Abelló David
- Abiola Olajide
- Abo mahadi Asmaa'
- Abo-khammash Areej
- Abou Chaar Mohamad K.
- Abou El.soud Moustafa Ramadan
- Abouelsoad Nervana
- Abraham Joyner
- Abreu da Silva Alberto
- Abu Ahammala Ayman B.
- Abu Al Amrain Mahmoud
- Abu Al-saleem Hasan
- Abu Alamrain Abdulwhhab
- Abu Alqumboz Amjad
- Abu Ataya Ahmed
- Abu hallalah Muad fathi khalleefah
- Abu Jamie Najlaa
- Abu Jayyab Israa
- Abu shua'ib Rana
- Abu Zainah Baraa
- Abu-Nimeh Samar
- Abu-Rous Mohammed R.
- Abu-srour Abrar
- Abuelhatal Hasan
- Abuelqomboz Ayham
- Abuhilal Baseel
- Abuhlaiga Ma'aly
- Abujamra Saleh
- Abukhalaf Sadi A.
- Abusalem Lana
- AbuSirrees Mahmoud
- Acevedo Veronica
- Acharya Rajgopal
- Achkasov Sergey
- Acosta Eric
- Adamo Karin
- Adamou Harissou
- Adams Jamie
- Adams Lawrence
- Adawi Samer
- Adebanjo Ademola
- Adel Marina
- Adel Sawsan
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji
- Adenuga Adedire
- Aderounmu Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesunkanmi Abdul-Rashid
- Adeyeye Ademola
- Adidharma Peter
- Adisa Adewale O
- Adnan Nour
- Afifi Amr Abdelghani
- Afifi Eman
- Afolayan Michael Olatunji
- Afzal Asma
- Agarwal Arnav
- Agarwal Raksheeth
- Agbakwuru Augustine
- Agbeko Anita Eseenam
- Aguilar Martinez Maria Del Mar
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlqvist Sandra
- Ahmad Izzuddin Ahmad Imran
- Ahmad Kasim
- Ahmad Sarwat
- Ahmed Ahmedgaber
- Ahmed Hazem Abdelkarem
- Ahmed Mariam
- Ahmed Nabila
- Ahmed Zahra
- Ainoa Eppu
- Aithie Joanna M S
- Ajani Costanza
- Ajao Akinlabi
- Ajiboye Anthony
- Ajmera Ankit
- Akande Oluwatosin
- Akaydin Elif
- Akbaba Ata Cem
- Akbar Sana Amir
- Akeel Nouf
- Akeem Aderogba Adeleke
- Akin Alp
- Akinkuolie Akinbolaji
- Akisheva Aygulya
- Akitikori Mabel Temisanren
- Akrida Ioanna
- Aktas Melik Kagan
- Al basos Iyad
- Al Farsi Maryam
- Al Nassrallah Majdi
- Al Sagheir Eman
- Al Saqqa Sara
- Al Saqqa Sara
- Al-Allaf Omar
- Al-Busaidi Ibrahim S.
- Al-Dhufri Ali
- Al-Himyari Hamza S.
- Al-Masri Mahmoud
- Al-Najjar Hani
- Al-Sabbagh Yusra
- Al-Shwaikh Samar
- Al-Slaibi Ibrahim
- Al-Taher Raed
- Al-Tammam Hiba
- Alabuzidi Aya
- Alagha Othman
- Alammarin Mohammad
- Alapatt John
- Alasttal Mohammed
- Alatise Olusegun Isaac
- Albaggar Marwa
- Albahnasawi Moath A.
- Albati Naif
- Alberga Anna
- Alberts Justin
- AlBsoul Ahmad
- Albsoul Nader
- Alcorta Rodrigo
- Alejandre Villalobos Cristina
- Alemdag Gökçe nur
- Alexander Philip
- Alfarra Nada
- Alfitory Asma
- Alhabil Belal
- Alhaj Ahmad
- Alherz Mohammad
- Alhimyar Maryam
- Ali Ahmad Syed Mustafa
- Ali SANI Samuel
- Ali Amr
- Ali Asmaa
- Ali Mahmoud
- Ali Shabina
- Alimi Marjan
- Aliosin Oleg
- Aliyu Halima
- Aljaafreh Almoutuz
- Aljaber Dana
- Aljaberi Loay
- Aljanfi Asma
- Aljiffry Murad
- Aljohmani Lylas
- Alkhaledi Ahmad
- Alkhatib Ala'a Aldeen
- Alkhatib Haya
- Alkhatib Mo'min
- Allen Ingabire J.C.
- Almasri Murad
- Almeida Braga Sara
- Almeida Filipe
- Almigheerbi Alabas
- Almoqayyad Abdelrahman
- Almuzghi Fakhruddin
- Alnoury Mostafa
- Alonso Batanero Ester
- Alqadi Mohammad
- Alsaid Bayan
- Alsalameh Barah
- Alsallaq Osama
- Alser Osaid
- Alshaar Muhammad
- Alsharef Tagwa
- Alsharqawi Nourah
- Alswerki Mohammad
- Altaf Amna
- Altaf Rabiya
- AlTaweel Mohammed
- Althini Abdulmunem Ahmed Mustafa
- Altibi Ahmed M.
- Altinel Yuksel
- Altiner Saygin
- Altomare Donato Francesco
- Altumei Zohoor
- Alvarez Rivera Alvaro Eduardo
- Alvarez-Cano Alethia
- Alves do Canto Brum Homero
- Alves Daniela Macedo
- Alves Magda
- Alvi Abdul
- Alwaheidi Malak
- Alwali Abdallah
- Alwerfally AbdulMawlay
- Alwhaidi Noor
- Alyafi Amr
- Alzabti Fatima
- Alzahaf Ahmed
- AlZohour Mohammad
- Amadou Magagi Ibrahim
- Amandito Radhian
- Amarin Justin Z.
- Amaro Margarida
- Ambrazevicius Marijus
- Amendola Alfonso
- Amin Leila
- Amine Souadka
- Amjad Talal
- Amorim Edgar
- Amro Adham
- Anandan Premkumar
- Anas khalifa Rawda
- Anastasio Lorenzo
- Andersson Yvette
- Andreotti Dario
- Andrew David
- André Benoît
- Ang Sue Ean
- Angel Miguel
- Anggita Gultom Phebe
- Annapureddy Naga
- Anokhin Evgeny
- Ansaloni Luca
- Ansarei Dhirar
- Ansari Abdul Basit
- Antaky Marco
- Anthony Natasha
- Anthoulakis Christos
- Antonopoulou Maria Ioanna
- Anwar Mohamed
- Anwer Abdul Wahid
- Anyanwu Chikamuche
- Anyanwu Lofty-John
- Anyanwu Mercy Chinemerem
- Anyomih Theophilus Teddy Kojo
- Appukuttan Akhila
- Aquilino Fabrizio
- Archibald Jess
- Arciénega Yañez María del pilar
- Argentou Maria-Ioanna
- Argudo Nuria
- Argyriou Eleftherios Orestis
- Arias Madrid Natalia
- Aribi Sarra
- Arifin Ghafur Rasyid
- Arizpe Daniel
- Arnaud Alexis P
- Arora Bharti
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- Arowolo Olukayode
- Arrangoiz Rodrigo
- Arslan Ekin
- Artigau Eva
- Ashfaq Ahsan
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- Asif Ashar
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- Asok Anjitha
- Assa Rawan
- Assalhi Mohamed
- Asta Martina
- Asti Emanuele Luigi Giuseppe
- Atakul Onur
- Atallah Khalid
- Atanasov Boyko
- Atawneh Mohammad
- Athamneh Sarah
- Ather Muaaz
- Athisayaraj Thomas
- Atkociunas Aivaras
- Attia Mohamed
- Au Angela
- Awad Israa
- Awadallah Haneen
- Awaji Kholoud
- Awesat Eman
- Awolowo Ajibola
- Ayandipo Omobolaji
- Ayash Mohammad
- Ayau Fernanda
- Ayesh Kholoud
- Ayman El-sawy Esraa
- Ayoub Rami
- Aytac Erman
- Ayub Bushra
- Ayub Saima
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- B L Ashika
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- Badr Esraa Tarek
- Badr Helmy
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- Badwe Rajendra
- Bafford Andrea Chao M.D.
- Baggaley Caitlin
- Bahroun Sumayyah Ghayth
- Baiao José Miguel
- Baiocchi Daniella
- Bairos Menezes Maria
- Baiu Ioana
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- Bajomo Oreoluwa
- Bake Jacques
- Baki Bahadir Emre
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- Balaawi Reem
- Balalis Dimitrios
- Balata Mohamed
- Balkarov Artem
- Ballouhey Quentin
- Balogun Olanrewaju
- Baloyiannis Ioannis
- Baltaci Ege
- Bamaca Ixcajoc Elvis Benjamin
- Banaz Tuba
- Banda Bitiel
- Banglani Muntaha
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- Banks Alexander
- Bannister Sharon
- Baranyai Zsolt
- Barati Nastaran
- Barbosa Camacho Francisco José
- Barbosa José
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- Barendegere Venerand
- Barghuthi Lutfi
- Barhoush Ola
- Barnes Nicole
- Baronio Gianluca
- Barreda Zelaya Lilian Elizabeth
- Barrera López Francisco Javier
- Barsic Neven
- Barter Charlotte
- Bartosiak Katarzyna
- Basarab Maksym
- Basso Stefano Maria Massimiliano.
- Bastiaenen Vivian
- Batashki Ilia
- Bath Michael
- Beattie Miriam
- Bedada Alemayehu Ginbo
- Belais Fanny
- Belal qadomi Asef
- Belev Nikolay
- Belli Andrea
- Beltrán de Heredia Juan
- Belvedere Angela
- Ben Dallah Najah
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- Benkabbou Amine
- Benke Marton
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- Bianchini Stefania
- Bianco Francesco
- Bibas Fatma
- Biccard Bruce M
- Bielosludtsev Oleksii
- Bienfait Mumbere
- Billy Matthew
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- Binetti Margherita
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- Blok Robin
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- Dogruoz Alper
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- Dollie Qaasim
- Dominguez Genieve
- Dominguez Joaquina
- Domini Edgar
- Dossou Francis
- Dousset Bertrand
- Draganic Brian
- Drake Thomas M
- Drane Andrew
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- Dudi-Venkata Nagendra Naidu
- Duggan William
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- Duller Alexander
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- Dworak Jadwiga
- Dzhumabaev Khasan
- Dziedzic Jacek
- Díaz Vico Tamara
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- Echeverria-Davila Guillermo
- Edirisooriya Monisha
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- Eid Esraa
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- Eklöv Karolina
- Ekpete Ogbonnia
- Ekwen Gerald
- El Gharmoul Tasnim
- El Jamassi Alaa
- El Muhtaseb M.S.
- El Nakeeb Ayman
- El sheikh Enas
- El Zoghby Naira
- El-Kahlout Sahar
- El-remaily Amira
- El-Sawy Aya
- El-taweel Alaa
- Elazab Yasmin
- Elbarouni Sofian
- Elbealawy Mohamed
- Elbeshina Aya Elseed
- Elblbessy Mahmood
- Eldeep Ahmed
- Eldeep Mostafa
- Eldmaty Asmaa
- Eldoseuky mohammed Amany
- Elemile Peter
- Elewaily Mohamed Ibrahim Elsayed
- Elfaituri Taha
- Elfallal Ahmed
- Elfanty Mahmoud
- ElFayoumy Ahmed Moustafa
- Elfeki Hossam
- Elfizri Zatira
- Elgammudi Mala
- Elghareeb Nourhan
- Elhadi Ahmed
- Elhadi Muhammed
- Elhajjaji Yasmine
- Elhelow Esraa
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- Elkabir Osama
- Elkhadragy Ahmed
- Elkhalawy Aya
- Ellaby-Hall Jordan
- Ellul Sarah
- Elmahdy Marwa
- Elmeslemany Nehal
- Elmokadem Aya
- Elqadi Muawiyah
- Elrais Safa
- Elsayed Mai
- Elsayed Mohammad
- Elshafei Houssein
- Elshafey Ahmed
- Elshaibani Mahmoud
- Elshatby Bassant
- Elshawy Mohamed Elemam
- Elsherbeny Mohammed Yasser
- Elsherif Fawzia
- Elshimy Ahmed
- Elsobky Hager
- Elteir Hana
- Eltoum Ruba
- Elzanfaly Ali Abdelazez
- Emara Eman
- Emeghara Okechukwu
- Emile Sameh
- Enumah Zachary
- Eraslan Huseyin
- Eray Ismail Cem
- Erkul Oguz
- Esbaga Fatima
- Escobar Dennis
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- Eskander John
- Eslam Sara
- Esmat Nourhan Ahmed
- Esper Asil
- Espin-Basany Eloy
- Espina Perez Beatriz
- Espinosa-Bravo Martin
- Esposito Giovanni
- Essam Ibrahim El Desouki Muhammad Ahmed Muhammad
- Essam Eman
- Estalagem Inês
- Estevez Tesouro José
- Eswaye Haitem
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- Manatakis Dimitrios K.
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- NA N.A.
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- Zabiyaka Mikhail
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- Zafar Syed Nabeel
- Zaffaroni Gloria
- Zahra Baryab
- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
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- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ângelo Miguel
- Älgå Andreas
- Çolak Elif
- Ümarik Toomas
- Šatkauskas Mindaugas
- Škimelyte Monika
- Šlenfuktas Vygintas
- Šuman Oliver
- Žatecký Jan
- Žumbakys Žygimantas
- Župan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 30/01/2021
- Field of study
© 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
- Abdullayev Seymur
- Abed Saeed
- Abelló David
- Abiola Olajide
- Abo mahadi Asmaa'
- Abo-khammash Areej
- Abou Chaar Mohamad K.
- Abou El.soud Moustafa Ramadan
- Abouelsoad Nervana
- Abraham Joyner
- Abreu da Silva Alberto
- Abu Ahammala Ayman B.
- Abu Al Amrain Mahmoud
- Abu Al-saleem Hasan
- Abu Alamrain Abdulwhhab
- Abu Alqumboz Amjad
- Abu Ataya Ahmed
- Abu hallalah Muad fathi khalleefah
- Abu Jamie Najlaa
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- Dollie Qaasim
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- Dominguez Joaquina
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- Essam Ibrahim El Desouki Muhammad Ahmed Muhammad
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- Figueiredo Ana Gabriela
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- Gnintedeme Olivier Tchianze
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- Wilson Michael
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- Winter Beatty Jasmine
- Winter Des
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- Wisselink Daan
- Wogensen Fredrik
- Wondoh Paul M.
- Wong Florence
- Wong Hsu Ven
- Wong Jane J
- Wong Jeremy
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- Wong Michael Pak-Kai
- Wong Sui-Weng
- Wong Tsz Lun Ernest
- Wood Lauren
- Woon-Shoo-Tong Xiao-Ming Sarah
- Wren Sherry
- Wuraola Funmilola
- Xanthopoulou Georgia
- Yabut Kenneth
- Yacoub Aseel
- Yaghi Nadine
- Yaghi Yasmine
- Yahia Mohamed Ali Mohamed
- Yakushkina Al'ona
- Yalçinkaya Ali
- Yang P Zichu
- Yanikoğlu Erkan
- Yanni Fady
- Yates Charlotte
- Ye Geoffrey
- Yeen Chin Leow
- Yemez Kürşat
- Yenidünya Nilüfer
- Yenli Edwin
- Yeo Jeremy
- Yeoh Andrea
- Yepez Raul
- Yeşilsancak Merve
- Yildirim Reyyan
- Yildiz Alp
- Yilmaz Duygu
- Yip Ching Wan
- Ylatoma Díaz Edgar Alcides
- Yong Shun Qi
- Yoong Andrel
- Yorke Joseph
- Yotsov Tsanko
- You Lucia
- Younes Eman
- Younes Maha
- Yousry Basant
- Yozgatli Tahir Koray
- Yu Kristin
- Yue Sum Yu Pansy
- Yunes Asmaa
- Yusuf Baasil
- Yüksel Osman
- Zabiyaka Mikhail
- Zachariah Sanoop Koshy
- Zafar Syed Nabeel
- Zaffaroni Gloria
- Zahra Baryab
- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
- Zambrana Campos Vanesa
- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ângelo Miguel
- Älgå Andreas
- Çolak Elif
- Ümarik Toomas
- Čepuliené Daiva
- Şahin Can
- Šatkauskas Mindaugas
- Škimelytè Monika
- Šlenfuktas Vygintas
- Šuman Oliver
- Žatecký Jan
- Žumbakys Žygimantas
- Župan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/07/2022
- Field of study
© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23–0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research
Pancreatic surgery outcomes: multicentre prospective snapshot study in 67 countries
- Author
- A Nizarudeen
- Aalem Hajer Abd Alhamed
- Ababneh Hazim
- Abbas Ahmed
- Abbas Aram
- Abbas Hussain
- Abbasi Arezou
- Abbassi Fariba
- Abbasy Jibran
- Abbood Ali H
- Abboud Kirellos
- Abdallah Ahmed
- Abdalsalam Sabriya Juma Ali
- Abdelaal Abdelrahman
- Abdelalemm Mohamed
- Abdelhafez Mohammed Hisham Zayan
- Abdelhalim Karim
- Abdeljalil Mahmoud
- Abdelkarem Mohamed
- Abdelmageed Abdelfatah
- Abdelmageed Abdelfatah
- Abdelmaksoud Mohamed
- Abdelmawgoud Sherif
- Abdelmawla Mohamed
- Abdelmawla Mohamed Osama Mohammed Kamel
- Abdelmoneim Noha
- Abdelnoor Ahmad
- Abdelrahman Fatma
- Abdelrazek Hussein A
- Abdelrhman Reham
- Abdelzaher Abdurrahman
- Abdelzaher Abdurrahman Taha
- Abdou Khaled
- Abdoun Meriem
- Abdualqader Mahmmoud
- Abdualqader Mahmmoud Yehia Mohammed
- Abdulhaq Aram
- Abduljawad Heba
- Abdullaev Abakar
- Abdullah Nik Azim Nik
- Abdulmonem Aya
- Abdulwahed Eman
- Abebrese John
- Abiyere Henry
- Abobakr Abobakr Mahfoz
- Aboelfath Shiamaa
- Abosamak Nour Eldin
- Abu-Elfatth Ahmed Mohammed
- Abu-Ghazal Sara
- Abu-Ghazal Sara Yassir
- Abuali Ahmed S A M E
- Abuelazm Mohamed
- Abuelnaga Yasmeen
- Abuelnaga Yasmeen
- Abughazal Sara Yasser
- Abuleil Amro
- Abusannuga Malek
- Abuzaina Khalil
- Adam Islam
- Aday Ulaş
- Adeyeye Ademola
- Adeyeye Nigeria Ademola
- Adham Mustapha
- Adhikari Krishna Mohan
- Affary Anter Al
- Afzal Ameer
- Afzal Iqraa
- Aghdassi Ali
- Ahmed Emad Ali
- Ahmed Mohamed Bahaa Eldin
- Ahmed Randa
- Ahmeed Sultan
- Ajayi Peter
- Akahoshi Keiichi
- Akbar Ali
- Akhtar Naseem
- Al-Abdi Radfan
- Al-Abed Omar
- Al-Ameri Saba
- Al-Ameri Saba Ahmed Ahmed Saleh
- Al-Asadi Mohammed Abdulkhaleq Mohammed Mohsen
- Al-Dowsh Nagra Are
- Al-Eryani Fatima
- Al-Faiq Siham
- Al-Haj Ahmad
- Al-Hyari Abdelkareem
- Al-Isawi Ali
- Al-juaifari Maytham Aqeel
- Al-Khawlani Qaeid
- Al-Kubati Waheeb
- Al-Maadani Basma
- Al-Mallah Rozana
- Al-Markiz Eman
- Al-Mekhlafi Ayat
- Al-Melhani Watheeq
- Al-Naggar Hamza
- Al-Naggar Hamza
- Al-Ogaili Mustafa
- Al-Qasrawi Shahd
- Al-Saban Rafat
- Al-saban Rafat Ameen Mohammed
- Al-Sader Maytham Al-Juaifari
- Al-Samawi Abdulaziz
- Al-Samawi Hytham
- Al-Sarireh Bilal
- Al-Shami Khayry
- Al-shami Manar
- Al-sharabi Ebrahim Ahmed Esmail
- Al-Shehari Mohammed
- Al-Tekreeti Sarah
- Alahmed Farouq
- Alahmed Hoor
- Alaimo Laura
- Alali Mahmoud Bilal
- Alannaz Omar
- Alansary Marwa Nasrelden
- Alatise Olusegun
- Alattas Zainab
- Alawna Reem
- Alazab Emad
- Albaba Safa'
- Albakry Rudaina
- Albar Aisha
- Albaraesi Mohammed N
- Albarouni Sofian
- Albishti Ahmed
- Alboridy Muneera
- Aldoescu Sorin
- AlDowsh Nagran Aref
- Aldressi Wafa
- Aldumaini Hamdan
- Alegria Cesar Rodriguez
- Alfano Marie Sophie
- Alfatah Maryam Abd
- Alfonso Cenon
- Alfurais Sarah
- Alghazo Heyam
- Alhaboob Nassir
- Alharthi Mohammed
- Alhashemi Mais
- Alhmaidi Riad
- Alhouri Ahmad
- Alhouri Ahmad Nabil
- Ali Ahmed Youssef Mohamed
- Ali Dina
- Ali Ramzi Abdullah Yahya
- Ali Ramzi Ali Abdullah Yahya
- Ali Suhil Ben
- Alissawi Subhi
- Alissawi Subhi Zahi
- Aliwy Marwan Al
- Aljaber Ahmad
- Aljamal Sarah
- Aljiffry Murad
- Alkhadem Maeen Ali
- Alkhaleel Wael
- Alkhateb Hossain
- Allah Mohamed Abd
- Allam Ahmed
- Allam Mohamed
- Allam Shrouq
- Allisiardi Fabrizio
- Alloush Ali
- Almarashi Hassan
- Almarkiz Eman
- Almasri Tabarak Abedlnaser
- Almassaudi Ali
- Almekhlafi Tofik
- Almiani Sari
- Almjersah Abdulrahman
- Alnammourah Walaa Mohammed
- Alnammourah Walaa Mohammed
- Alnimr Ahmed
- Aloulou Marwa
- Alowjali Fatoom
- Alsabah Mohamed
- Alsabbagh Feras
- AlSaffaf Mohamed
- Alsanany Ghadeer Mohammed
- Alsayadi Ramzi
- Alshaghel Mohammed
- Alsharabi Ebrahim
- Alshareea Entisar
- Alsharif Doaa
- Alsharif Doaa Sabry
- Alsharif Doaa Sabry
- Alsharif Doaa Sabry
- Alshatshat Abdulhadi
- Alsori Mohamed
- Alsoudani Ali
- Altatari Abdulrahman
- Altatari Ahmad Mohammad
- Alwafy Khaled
- Alwan Hussein Mohammed
- Alyasin Ismaeil
- Alzabadiah Asmaa Hasan Mohammad
- Alzghoul Mohammad W
- Alzoubi Mohammed
- Amarin Zouhair
- Amic Fedor
- Amina Houmada
- Ammar Khaled
- Amrani Laila
- Amro Sarah
- Amro Sarah
- Anas Omar
- Anas Omar
- Anastasi Alessandro
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- Weber Markus
- Wei Alice
- Wei Kongyuan
- Wei Kongyuan
- Weitz Jürgen
- Wellner Ulrich
- Welsch Thilo
- Welsh Fraser
- Wen Daniel
- Wennerblom Johanna Hansson
- Wenning Anna Silvia
- Wicherts Dennis
- Wierzchowski Michał
- Wikar Tomasz
- Williamsson Caroline
- Windsor John
- Winslow Emily
- Wlazlak Michal
- Wolfgang Christopher
- Wu Chien Hui
- Wu Chien Hui
- Wüllenweber Hans-Peter
- Wyroślak-Najs Justyna
- Yadav Kaushal
- Yadev Induprabha
- Yadev Induprabha
- Yaghan Rami
- Yamamoto Tomohisa
- Yang Po-Chih
- Yassin Laya Moayyad Ahmed
- Yassin Raya
- Yegen Cumhur
- Yeo Charles
- Yesilyurt Degercan
- Yip Vincent
- Yoong Boon
- Yoong Boon Koon
- Younes Eman
- Younes Eman
- Young Alistair
- Yousef Amal
- Youssef Amal
- Yu Ming-Chin
- Zacharakis Emmanouil
- Zacharoulis Dimitrios
- Zachiotis Marinos
- Zagainov Vladimir
- Zaharie Florin
- Zahed Mohamed
- Zahed Mohamed Samir Mohamed
- Zakaria Andee Dzulkarnaen
- Zamri Fatimah Mardhiyyah Binti
- Zanatta Michela
- Zanello Matteo
- Zanini Nicola
- Zanus Giacomo
- Zanus Giacomo
- Zaruba Pavel
- Zawia Ali
- Zayed Ahmed
- Zdujic Predrag
- Zedelj Jurica
- Zeh Herbert J
- Zentar Aziz
- Zerbi Alessandro
- Zidan Taha
- Zidan Taha
- Zironda Andrea
- Zitawi Abdullah
- Zivanovic Marko
- Zogopoulos George
- Zonta Sandro
- Zonta Sandro
- Zorrilla Carlos Florez
- Zozaya Gabriel
- Zreqat Qusai
- Zuhdi Zamri
- Zuhdy Mohammad
- Zygomalas Apollon
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: Pancreatic surgery remains associated with high morbidity rates. Although postoperative mortality appears to have improved with specialization, the outcomes reported in the literature reflect the activity of highly specialized centres. The aim of this study was to evaluate the outcomes following pancreatic surgery worldwide.Methods: This was an international, prospective, multicentre, cross-sectional snapshot study of consecutive patients undergoing pancreatic operations worldwide in a 3-month interval in 2021. The primary outcome was postoperative mortality within 90 days of surgery. Multivariable logistic regression was used to explore relationships with Human Development Index (HDI) and other parameters.Results: A total of 4223 patients from 67 countries were analysed. A complication of any severity was detected in 68.7 percent of patients (2901 of 4223). Major complication rates (Clavien-Dindo grade at least IIIa) were 24, 18, and 27 percent, and mortality rates were 10, 5, and 5 per cent in low-to-middle-, high-, and very high-HDI countries respectively. The 90-day postoperative mortality rate was 5.4 per cent (229 of 4223) overall, but was significantly higher in the low-to-middle-HDI group (adjusted OR 2.88, 95 per cent c.i. 1.80 to 4.48). The overall failure-to-rescue rate was 21 percent; however, it was 41 per cent in low-to-middle-compared with 19 per cent in very high-HDI countries.Conclusion: Excess mortality in low-to-middle-HDI countries could be attributable to failure to rescue of patients from severe complications. The authors call for a collaborative response from international and regional associations of pancreatic surgeons to address management related to death from postoperative complications to tackle the global disparities in the outcomes of pancreatic surgery (NCT04652271; ISRCTN95140761)