Management reference for nature reserve networks based on MaxEnt modeling and gap analysis: a case study of the brown–eared pheasant in China

Referencia para la gestión de las redes de reservas naturales basada en la creación de modelos MaxEnt y el análisis de deficiencias: un estudio del faisán orejudo pardo en China La planificación de reservas naturales y la creación de redes son importantes para la conservación de los hábitats y la fauna silvestre. Los análisis de las deficiencias son instrumentos eficientes y fiables para establecer un orden de prioridad entre las iniciativas de conservación de hábitats, en especial por lo que respecta a las especies en peligro de extinción. Proponemos un plan de conservación para el faisán orejudo pardo, Crossoptilon mantchuricum, mediante la determinación de las zonas con una protección insuficiente en las 14  reservas naturales existentes. En total, se seleccionaron 45  localidades y 11  variables ambientales en función de las características del uso del hábitat del faisán orejudo pardo, y se utilizó un modelo de máxima entropía (MaxEnt) para obtener la distribución de la especie. Los resultados del modelo MaxEnt mostraron una elevada precisión de predicción. Los resultados del análisis de las deficiencias revelaron que en las montañas Luliang, en Shanxi, y las montañasXiaowutai, en Hebei, la protección era insuficiente. Encontramos 458  km2 de hábitat óptimo y 1.390  km2 de hábitat moderadamente adecuado dentro de los límites de la reserva natural nacional. No obstante, casi 1.861  km2 del hábitat óptimo y 17.035  km2 del hábitat moderadamente adecuado no estaban protegidos, lo que equivale al 9,0% y el 82,1%, respectivamente, del hábitat adecuado total. La mayor parte de la superficie sin protección estaba formada por hábitat moderadamente adecuado para el faisán orejudo pardo y debería considerarse prioritaria en las iniciativas futuras de conservación. Hay nueve reservas naturales a lo largo de un eje norte–sur en las montañas Luliang que forma un pasillo ecológico. Para mantener la integridad, originalidad y continuidad de estos hábitats y, por tanto, proteger el faisán orejudo pardo, deberían reforzarse los departamentos locales de conservación con miras a mejorar la gestión de la reserva natural a escala provincial y poner en práctica eficazmente las iniciativas de conservación.Referencia para la gestión de las redes de reservas naturales basada en la creación de modelos MaxEnt y el análisis de deficiencias: un estudio del faisán orejudo pardo en China La planificación de reservas naturales y la creación de redes son importantes para la conservación de los hábitats y la fauna silvestre. Los análisis de las deficiencias son instrumentos eficientes y fiables para establecer un orden de prioridad entre las iniciativas de conservación de hábitats, en especial por lo que respecta a las especies en peligro de extinción. Proponemos un plan de conservación para el faisán orejudo pardo, Crossoptilon mantchuricum, mediante la determinación de las zonas con una protección insuficiente en las 14  reservas naturales existentes. En total, se seleccionaron 45  localidades y 11  variables ambientales en función de las características del uso del hábitat del faisán orejudo pardo, y se utilizó un modelo de máxima entropía (MaxEnt) para obtener la distribución de la especie. Los resultados del modelo MaxEnt mostraron una elevada precisión de predicción. Los resultados del análisis de las deficiencias revelaron que en las montañas Luliang, en Shanxi, y las montañasXiaowutai, en Hebei, la protección era insuficiente. Encontramos 458  km2 de hábitat óptimo y 1.390  km2 de hábitat moderadamente adecuado dentro de los límites de la reserva natural nacional. No obstante, casi 1.861  km2 del hábitat óptimo y 17.035  km2 del hábitat moderadamente adecuado no estaban protegidos, lo que equivale al 9,0% y el 82,1%, respectivamente, del hábitat adecuado total. La mayor parte de la superficie sin protección estaba formada por hábitat moderadamente adecuado para el faisán orejudo pardo y debería considerarse prioritaria en las iniciativas futuras de conservación. Hay nueve reservas naturales a lo largo de un eje norte–sur en las montañas Luliang que forma un pasillo ecológico. Para mantener la integridad, originalidad y continuidad de estos hábitats y, por tanto, proteger el faisán orejudo pardo, deberían reforzarse los departamentos locales de conservación con miras a mejorar la gestión de la reserva natural a escala provincial y poner en práctica eficazmente las iniciativas de conservación.Nature reserve designs and networks are important for wildlife and habitat conservation. Gap analyses are efficient and reliable tools for prioritizing habitat conservation efforts, especially when considering endangered species. We propose a conservation plan for the brown–eared pheasant, Crossoptilon mantchuricum, by identifying protection gap areas based on 14 existing nature reserves. A total of 45 locality sites and 11 environmental variables were selected according to the characteristics of habitat use of the brown–eared pheasant and applied to a maximum entropy (MaxEnt) model to obtain the species distribution. The MaxEnt model results showed a high prediction accuracy. The gap analysis results revealed that the Luliang Mountains in Shanxi and the Xiaowutai Mountains in Hebei had protection gaps. We found 458 km2 of optimum habitat and 1,390 km2 of moderately suitable habitat within the national nature reserve range. However, almost 1,861 km2 of the optimum habitat and 17,035 km2 of the moderately suitable habitat were unprotected, equivalent to 9.0% and 82.1%, respectively, of the total suitable habitat. Most of the unprotected area comprised moderately suitable habitat for brown–eared pheasant and should be prioritized in future conservation efforts. There are nine nature reserves along a north–to–south range in the Luliang Mountains that form a wildlife habitat corridor. To maintain the integrity, originality, and continuity of these habitats and thus protect brown–eared pheasants, local conservation departments should be strengthened to improve provincial nature reserve management and successfully carry out conservation efforts

Dissecting Sources of Quantitative Gene Expression Pattern Divergence Between Drosophila Species

The function of a transcriptional circuit is compared in three closely related species of Drosophila. Using quantitative imaging of gene expression, targeted transgenic reporter fly lines, and a computational framework, the sources of their differing expression outputs are identified

Systematic literature review of prediction techniques to identify work skillset

A mismatch of skillsets is a main cause to the unemployment in Malaysia. It is a situation where the level and work skillset that are available do not match the market demands and the individual does not know how to identify the skills that they have. To deal with this problem, prediction techniques is used to assist in identifying work-appropriate skills for individual. Thus, a systematic literature review (SLR) on predicting work skillsets using prediction techniques is proposed. The aim of this study is to give an overview on the prediction techniques that have been used to predict work skillset and the accuracy of the techniques. We use SLR to identify 383 prediction techniques studies for identifying skills published from 2014 to 2019. As a result, 9 studies report adequate information and methodology according to our criteria and apply. From the studies, classification techniques are used for predicting work skillset. The algorithms used is Random Forest with precision is 99%. From this study, a future study will be conducted by developing a prediction model to help identifying appropriate work skillsets to meet current needs and identifying the levels of skills they have. The significant of this study is the researchers are able to understand deeply about the prediction techniques used to identify work skillset and the accuracy of the techniques used

Longitudinal decrease in blood oxygenation level dependent response in cerebral amyloid angiopathy

AbstractLower blood oxygenation level dependent (BOLD) signal changes in response to a visual stimulus in functional magnetic resonance imaging (fMRI) have been observed in cross-sectional studies of cerebral amyloid angiopathy (CAA), and are presumed to reflect impaired vascular reactivity. We used fMRI to detect a longitudinal change in BOLD responses to a visual stimulus in CAA, and to determine any correlations between these changes and other established biomarkers of CAA progression. Data were acquired from 22 patients diagnosed with probable CAA (using the Boston Criteria) and 16 healthy controls at baseline and one year. BOLD data were generated from the 200 most active voxels of the primary visual cortex during the fMRI visual stimulus (passively viewing an alternating checkerboard pattern). In general, BOLD amplitudes were lower at one year compared to baseline in patients with CAA (p=0.01) but were unchanged in controls (p=0.18). The longitudinal difference in BOLD amplitudes was significantly lower in CAA compared to controls (p<0.001). White matter hyperintensity (WMH) volumes and number of cerebral microbleeds, both presumed to reflect CAA-mediated vascular injury, increased over time in CAA (p=0.007 and p=0.001, respectively). Longitudinal increases in WMH (rs=0.04, p=0.86) or cerebral microbleeds (rs=−0.18, p=0.45) were not associated with the longitudinal decrease in BOLD amplitudes

AXL modulates extracellular matrix protein expression and is essential for invasion and metastasis in endometrial cancer

The receptor tyrosine kinase AXL promotes migration, invasion, and metastasis. Here, we evaluated the role of AXL in endometrial cancer. High immunohistochemical expression of AXL was found in 76% (63/83) of advanced-stage, and 77% (82/107) of high-grade specimens and correlated with worse survival in uterine serous cancer patients. In vitro, genetic silencing of AXL inhibited migration and invasion but had no effect on proliferation of ARK1 endometrial cancer cells. AXL-deficient cells showed significantly decreased expression of phospho-AKT as well as uPA, MMP-1, MMP-2, MMP-3, and MMP-9. In a xenograft model of human uterine serous carcinoma with AXL-deficient ARK1 cells, there was significantly less tumor burden than xenografts with control ARK1 cells. Together, these findings underscore the therapeutic potentials of AXL as a candidate target for treatment of metastatic endometrial cancer

Continuous Processing and Efficient in Situ\textit{in Situ} Reaction Monitoring of a Hypervalent Iodine(III) Mediated Cyclopropanation Using Benchtop NMR Spectroscopy

Real-time NMR spectroscopy has proven to be a rapid and an effective monitoring tool to study the hypervalent iodine(III) mediated cyclopropanation. With the ever increasing number of new synthetic methods for carbon−carbon bond formation, the NMR $\textit{in situ}$ monitoring of reactions is becoming a highly desirable enabling method. In this study, we have demonstrated the versatility of benchtop NMR using inline and online real-time monitoring methods to access mutually complementary information for process understanding, and we developed new approaches for real-time monitoring addressing challenges associated with better integration into continuous processes.University of Cambridge (Daphne Jackson Fellowship), iCON through CMAC (Grant ID: RG74817), Engineering and Physical Sciences Research Council (Critical Mass grant (Grant ID: EP/K009494K/1), Core Capability grant (Grant ID: EP/K039520/1

Modulation of Sn concentration in ZnO nanorod array: intensification on the conductivity and humidity sensing properties

Tin (Sn)-doped zinc oxide (ZnO) nanorod arrays (TZO) were synthesized onto aluminum-doped ZnO-coated glass substrate via a facile sonicated sol–gel immersion method for humidity sensor applications. These nanorod arrays were grown at different Sn concentrations ranging from 0.6 to 3 at.%. X-ray diffraction patterns showed that the deposited TZO arrays exhibited a wurtzite structure. The stress/strain condition of the ZnO film metamorphosed from tensile strain/compressive stress to compressive strain/tensile stress when the Sn concentrations increased. Results indicated that 1 at.% Sn doping of TZO, which has the lowest tensile stress of 0.14 GPa, generated the highest conductivity of 1.31 S cm− 1. In addition, 1 at.% Sn doping of TZO possessed superior sensitivity to a humidity of 3.36. These results revealed that the optimum performance of a humidity-sensing device can be obtained mainly by controlling the amount of extrinsic element in a ZnO film

Measurement of the cross-section and charge asymmetry of WW bosons produced in proton-proton collisions at s=8\sqrt{s}=8 TeV with the ATLAS detector

This paper presents measurements of the $W^+ \rightarrow \mu^+\nu$ and $W^- \rightarrow \mu^-\nu$ cross-sections and the associated charge asymmetry as a function of the absolute pseudorapidity of the decay muon. The data were collected in proton--proton collisions at a centre-of-mass energy of 8 TeV with the ATLAS experiment at the LHC and correspond to a total integrated luminosity of 20.2~\mbox{fb^{-1}}. The precision of the cross-section measurements varies between 0.8% to 1.5% as a function of the pseudorapidity, excluding the 1.9% uncertainty on the integrated luminosity. The charge asymmetry is measured with an uncertainty between 0.002 and 0.003. The results are compared with predictions based on next-to-next-to-leading-order calculations with various parton distribution functions and have the sensitivity to discriminate between them.Comment: 38 pages in total, author list starting page 22, 5 figures, 4 tables, submitted to EPJC. All figures including auxiliary figures are available at https://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/STDM-2017-13