99 research outputs found
On Quantum Capacity of Compound Channels
In this paper we address the issue of universal or robust communication over
quantum channels. Specifically, we consider memoryless communication scenario
with channel uncertainty which is an analog of compound channel in classical
information theory. We determine the quantum capacity of finite compound
channels and arbitrary compound channels with informed decoder. Our approach in
the finite case is based on the observation that perfect channel knowledge at
the decoder does not increase the capacity of finite quantum compound channels.
As a consequence we obtain coding theorem for finite quantum averaged channels,
the simplest class of channels with long-term memory. The extension of these
results to quantum compound channels with uninformed encoder and decoder, and
infinitely many constituents remains an open problem.Comment: 16 pages, no figure
Fracture in Three-Dimensional Fuse Networks
We report on large scale numerical simulations of fracture surfaces using
random fuse networks for two very different disorders. There are some
properties and exponents that are different for the two distributions, but
others, notably the roughness exponents, seem universal. For the universal
roughness exponent we found a value of zeta = 0.62 +/- 0.05. In contrast to
what is observed in two dimensions, this value is lower than that reported in
experimental studies of brittle fractures, and rules out the minimal energy
surface exponent, 0.41 +/- 0.01.Comment: 4 pages, RevTeX, 5 figures, Postscrip
RADIATION DEFECTS STUDY OF BERILLIUM OXIDE BY LUMINESCENCE SPECTROSCOPY METHODS
Defects in beryllium oxide crystals are investigated. Neutron irradiated, thermally colored and pristine crystals studied using X-ray spectra and TSL curves obtained for samples. In conclusion, defect structure in thermally colored and neutron irradiated crystals is compared
Nonlinear spectral calculus and super-expanders
Nonlinear spectral gaps with respect to uniformly convex normed spaces are
shown to satisfy a spectral calculus inequality that establishes their decay
along Cesaro averages. Nonlinear spectral gaps of graphs are also shown to
behave sub-multiplicatively under zigzag products. These results yield a
combinatorial construction of super-expanders, i.e., a sequence of 3-regular
graphs that does not admit a coarse embedding into any uniformly convex normed
space.Comment: Typos fixed based on referee comments. Some of the results of this
paper were announced in arXiv:0910.2041. The corresponding parts of
arXiv:0910.2041 are subsumed by the current pape
The Laser Astrometric Test of Relativity Mission
This paper discusses new fundamental physics experiment to test relativistic
gravity at the accuracy better than the effects of the 2nd order in the
gravitational field strength. The Laser Astrometric Test Of Relativity (LATOR)
mission uses laser interferometry between two micro-spacecraft whose lines of
sight pass close by the Sun to accurately measure deflection of light in the
solar gravity. The key element of the experimental design is a redundant
geometry optical truss provided by a long-baseline (100 m) multi-channel
stellar optical interferometer placed on the International Space Station. The
geometric redundancy enables LATOR to measure the departure from Euclidean
geometry caused by the solar gravity field to a very high accuracy. LATOR will
not only improve the value of the parameterized post-Newtonian (PPN) parameter
gamma to unprecedented levels of accuracy of 1 part in 1e8, it will also reach
ability to measure effects of the next post-Newtonian order (1/c^4) of light
deflection resulting from gravity's intrinsic non-linearity. The solar
quadrupole moment parameter, J2, will be measured with high precision, as well
as a variety of other relativistic. LATOR will lead to very robust advances in
the tests of fundamental physics: this mission could discover a violation or
extension of general relativity, or reveal the presence of an additional long
range interaction in the physical law. There are no analogs to the LATOR
experiment; it is unique and is a natural culmination of solar system gravity
experiments.Comment: 8 pages, 2 figures, invited talk given at the Second International
Conference on Particle and Fundamental Physics in Space (SpacePart'03), 10-12
December 2003, Washington, D
Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics
Essential metals, such as iron and copper, play a critical role in a plethora of cellular processes including cell growth and proliferation. However, concomitantly, excess of these metal ions in the body can have deleterious effects due to their ability to generate cytotoxic reactive oxygen species (ROS). Thus, the human body has evolved a very well-orchestrated metabolic system that keeps tight control on the levels of these metal ions. Considering their very high proliferation rate, cancer cells require a high abundance of these metals compared to their normal counterparts. Interestingly, new anti-cancer agents that take advantage of the sensitivity of cancer cells to metal sequestration and their susceptibility to ROS have been developed. These ligands can avidly bind metal ions to form redox active metal complexes, which lead to generation of cytotoxic ROS. Furthermore, these agents also act as potent metastasis suppressors due to their ability to up-regulate the metastasis suppressor gene, N-myc downstream regulated gene 1. This review discusses the importance of iron and copper in the metabolism and progression of cancer, how they can be exploited to target tumors and the clinical translation of novel anti-cancer chemotherapeutics
Iron Behaving Badly: Inappropriate Iron Chelation as a Major Contributor to the Aetiology of Vascular and Other Progressive Inflammatory and Degenerative Diseases
The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular "reactive oxygen species" (ROSs)
can exhibit a number of biological effects, they are not of themselves
excessively reactive and thus they are not especially damaging at physiological
concentrations. However, their reactions with poorly liganded iron species can
lead to the catalytic production of the very reactive and dangerous hydroxyl
radical, which is exceptionally damaging, and a major cause of chronic
inflammation. We review the considerable and wide-ranging evidence for the
involvement of this combination of (su)peroxide and poorly liganded iron in a
large number of physiological and indeed pathological processes and
inflammatory disorders, especially those involving the progressive degradation
of cellular and organismal performance. These diseases share a great many
similarities and thus might be considered to have a common cause (i.e.
iron-catalysed free radical and especially hydroxyl radical generation). The
studies reviewed include those focused on a series of cardiovascular, metabolic
and neurological diseases, where iron can be found at the sites of plaques and
lesions, as well as studies showing the significance of iron to aging and
longevity. The effective chelation of iron by natural or synthetic ligands is
thus of major physiological (and potentially therapeutic) importance. As
systems properties, we need to recognise that physiological observables have
multiple molecular causes, and studying them in isolation leads to inconsistent
patterns of apparent causality when it is the simultaneous combination of
multiple factors that is responsible. This explains, for instance, the
decidedly mixed effects of antioxidants that have been observed, etc...Comment: 159 pages, including 9 Figs and 2184 reference
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