Of mongooses and mitigation: ecological analogues to geoengineering

Anthropogenic global warming is a growing environmental problem resulting from unintentional human intervention in the global climate system. If employed as a response strategy, geoengineering would represent an additional intentional human intervention in the climate system, with the intent of decreasing net climate impacts. There is a rich and fascinating history of human intervention in environmental systems, with many specific examples from ecology of deliberate human intervention aimed at correcting or decreasing the impact of previous unintentionally created problems. Additional interventions do not always bring the intended results, and in many cases there is evidence that net impacts have increased with the degree of human intervention. In this letter, we report some of the examples in the scientific literature that have documented such human interventions in environmental systems, which may serve as analogues to geoengineering. We argue that a high degree of system understanding is required for increased intervention to lead to decreased impacts. Given our current level of understanding of the climate system, it is likely that the result of at least some geoengineering efforts would follow previous ecological examples where increased human intervention has led to an overall increase in negative environmental consequences

The significance of the largest scale CMB fluctuations in WMAP

We investigate anomalies reported in the Cosmic Microwave Background maps from the Wilkinson Microwave Anisotropy Probe (WMAP) satellite on very large angular scales and discuss possible interpretations. Three independent anomalies involve the quadrupole and octopole: 1. The cosmic quadrupole on its own is anomalous at the 1-in-20 level by being low (the cut-sky quadrupole measured by the WMAP team is more strikingly low, apparently due to a coincidence in the orientation of our Galaxy of no cosmological significance); 2. The cosmic octopole on its own is anomalous at the 1-in-20 level by being very planar; 3. The alignment between the quadrupole and octopole is anomalous at the 1-in-60 level. Although the a priori chance of all three occurring is 1 in 24000, the multitude of alternative anomalies one could have looked for dilutes the significance of such a posteriori statistics. The simplest small universe model where the universe has toroidal topology with one small dimension of order half the horizon scale, in the direction towards Virgo, could explain the three items above. However, we rule this model out using two topological tests: the S-statistic and the matched circle test.Comment: N.B. that our results do not rule out the recently proposed dodecahedron model of Luminet, Weeks, Riazuelo, Lehoucq & Uzan, which has a 36 degree twist between matched circles. 12 pages, 5 figs; more info at http://www.hep.upenn.edu/~angelica/topology.htm

Lung MRI with hyperpolarised gases : current & future clinical perspectives

The use of pulmonary MRI in a clinical setting has historically been limited. Whilst CT remains the gold-standard for structural lung imaging in many clinical indications, technical developments in ultrashort and zero echo time MRI techniques are beginning to help realise non-ionising structural imaging in certain lung disorders. In this invited review, we discuss a complementary technique – hyperpolarised (HP) gas MRI with inhaled 3He and 129Xe – a method for functional and microstructural imaging of the lung that has great potential as a clinical tool for early detection and improved understanding of pathophysiology in many lung diseases. HP gas MRI now has the potential to make an impact on clinical management by enabling safe, sensitive monitoring of disease progression and response to therapy. With reference to the significant evidence base gathered over the last two decades, we review HP gas MRI studies in patients with a range of pulmonary disorders, including COPD/emphysema, asthma, cystic fibrosis, and interstitial lung disease. We provide several examples of our experience in Sheffield of using these techniques in a diagnostic clinical setting in challenging adult and paediatric lung diseases

Transient up- and down-regulation of expression of myosin light chain 2 and myostatin mRNA mark the changes from stratified hyperplasia to muscle fiber hypertrophy in larvae of gilthead sea bream (Sparus aurata L.)

Hyperplasia and hypertrophy are the two mechanisms by which muscle develops and grows. We study these two mechanisms, during the early development of white muscle in Sparus aurata, by means of histology and the expression of structural and regulatory genes. A clear stage of stratified hyperplasia was identified early in the development of gilthead sea bream but ceased by 35 dph when hypertrophy took over. Mosaic recruitment of new white fibers began as soon as 60 dph. The genes mlc2a and mlc2b were expressed at various levels during the main phases of hyperplasia and hypertrophy. The genes myog and mlc2a were significantly up-regulated during the intensive stratified formation of new fibers and their expression was significantly correlated. Expression of mstn1 and igf1 increased at 35 dph, appeared to regulate the hyperplasia-to-hypertrophy transition, and may have stimulated the expression of mlc2a, mlc2b and col1a1 at the onset of mosaic hyperplasia. The up-regulation of mstn1 at transitional phases in muscle development indicates a dual regulatory role of myostatin in fish larval muscle growth

X-ray stacking of Lyman break galaxies in the 4 Ms CDF-S: X-ray luminosities and star formation rates across cosmic time

Context. Lyman break galaxies (LBGs) are widely thought to be prototypical young galaxies in the early universe, particularly representative of those undergoing massive events of star formation. Therefore, LBGs should produce significant amounts of X-ray emission. Aims. We aim to trace the X-ray luminosity of LBGs across cosmic time and from that derive constraints on their star formation history. Methods. We utilize the newly released 4 Ms mosaic obtained with the Chandra X-ray Observatory, the deepest X-ray image to date, alongside with the superb spectroscopic data sets available in the CDF-S survey region to construct large but nearly uncontaminated samples of LBGs across a wide range of redshift (0.5 < z < 4.5) which can be used as input samples for stacking experiments. This approach allows us to trace the X-ray emission of LBGs to even lower, previously unreachable, flux density limits (~10 -18 mW m -2) and therefore to larger redshifts. Results. We reliably detect soft-band X-ray emission from all our input redshift bins except for the highest redshift (z ~ 4) one. From that we derive rest-frame 2-10 keV luminosities and infer star formation rates and stellar masses. We find that star formation in LBGs peaks at a redshift of z peak 3.5 and then decreases quickly. We also see a characteristic peak in the specific star formation rate (sSFR = SFR/M -) at this redshift. Furthermore, we calculate the contribution of LBGs to the total cosmic star formation rate density (SFRD) and find that the contribution of LBGs is negligible. Therefore, we conclude that most of the star formation in the early universe takes place in lower luminosity galaxies as suggested by hierarchical structure formation models

Spatial and Sex-Specific Variation in Growth of Albacore Tuna (Thunnus alalunga) across the South Pacific Ocean

Spatial variation in growth is a common feature of demersal fish populations which often exist as discrete adult sub-populations linked by a pelagic larval stage. However, it remains unclear whether variation in growth occurs at similar spatial scales for populations of highly migratory pelagic species, such as tuna. We examined spatial variation in growth of albacore Thunnus alalunga across 90° of longitude in the South Pacific Ocean from the east coast of Australia to the Pitcairn Islands. Using length-at-age data from a validated ageing method we found evidence for significant variation in length-at-age and growth parameters (L∞ and k) between sexes and across longitudes. Growth trajectories were similar between sexes up until four years of age, after which the length-at-age for males was, on average, greater than that for females. Males reached an average maximum size more than 8 cm larger than females. Length-at-age and growth parameters were consistently greater at more easterly longitudes than at westerly longitudes for both females and males. Our results provide strong evidence that finer spatial structure exists within the South Pacific albacore stock and raises the question of whether the scale of their “highly migratory” nature should be re-assessed. Future stock assessment models for South Pacific albacore should consider sex-specific growth curves and spatial variation in growth within the stock

Galaxy counterparts of intervening high-z sub-DLAs/DLAs and MgII absorbers towards gamma-ray bursts

We present the first search for galaxy counterparts of intervening high-z (2<z< 3.6) sub-DLAs and DLAs towards GRBs. Our final sample comprises of five intervening sub-DLAs and DLAs in four GRB fields. To identify candidate galaxy counterparts of the absorbers we use deep optical and near-infrared imaging, and low-, mid- and high-resolution spectroscopy acquired with 6 to 10-m class telescopes, the Hubble and the Spitzer space telescopes. Furthermore, we use the spectroscopic information and spectral-energy-distribution fitting techniques to study them in detail. Our main result is the detection and spectroscopic confirmation of the galaxy counterpart of the intervening DLA at z=3.096 in the field of GRB 070721B (z_GRB=3.6298) as proposed by other authors. We also identify good candidates for the galaxy counterparts of the two strong MgII absorbers at z=0.6915 and 1.4288 towards GRB 050820A (z_GRB=2.615). The properties of the detected DLA galaxy are typical for Lyman-break galaxies (LBGs) at similar redshifts; a young, highly starforming galaxy that shows evidence for a galactic outflow. This supports the hypothesis that a DLA can be the gaseous halo of an LBG. In addition, we report a redshift coincidence of different objects associated with metal lines in the same field, separated by 130-161 kpc. The high detection rate of three correlated structures on a length scale as small as ~150 kpc in two pairs of lines of sight is intriguing. The absorbers in each of these are most likely not part of the same gravitationally bound structure. They more likely represent groups of galaxies.Comment: A&A, accepted; 20 pages in journal format; 12 pages main text, 1 page references, 1 page appendix, 14 figures, 8 tables. Note, Tables 1 and 4 look different than in the journal but are identica

Planck 2015 results. XVIII. Background geometry and topology of the Universe

Maps of cosmic microwave background (CMB) temperature and polarization from the 2015 release of Planck data provide the highestquality full-sky view of the surface of last scattering available to date. This enables us to detect possible departures from a globally isotropic cosmology. We present the first searches using CMB polarization for correlations induced by a possible non-trivial topology with a fundamental domain that intersects, or nearly intersects, the last-scattering surface (at comoving distance χrec), both via a direct scan for matched circular patterns at the intersections and by an optimal likelihood calculation for specific topologies. We specialize to flat spaces with cubic toroidal (T3) and slab (T1) topologies, finding that explicit searches for the latter are sensitive to other topologies with antipodal symmetry. These searches yield no detection of a compact topology with a scale below the diameter of the last-scattering surface. The limits on the radius ℛi of the largest sphere inscribed in the fundamental domain (at log-likelihood ratio Δlnℒ > −5 relative to a simply-connected flat Planck best-fit model) are: ℛi > 0.97 χrec for the T3 cubic torus; and ℛi > 0.56 χrec for the T1 slab. The limit for the T3 cubic torus from the matched-circles search is numerically equivalent, ℛi > 0.97 χrec at 99% confidence level from polarization data alone. We also perform a Bayesian search for an anisotropic global Bianchi VIIh geometry. In the non-physical setting, where the Bianchi cosmology is decoupled from the standard cosmology, Planck temperature data favour the inclusion of a Bianchi component with a Bayes factor of at least 2.3 units of log-evidence. However, the cosmological parameters that generate this pattern are in strong disagreement with those found from CMB anisotropy data alone. Fitting the induced polarization pattern for this model to the Planck data requires an amplitude of −0.10 ± 0.04 compared to the value of + 1 if the model were to be correct. In the physically motivated setting, where the Bianchi parameters are coupled and fitted simultaneously with the standard cosmological parameters, we find no evidence for a Bianchi VIIh cosmology and constrain the vorticity of such models to (ω/H)0 < 7.6 × 10-10 (95% CL)