42 research outputs found
The Matter in Extreme Conditions instrument at the Linac Coherent Light Source
- Author
- Alex Wallace
- Alice Callen
- Andreas Schropp
- Belyaev
- Blaj
- Bob Nagler
- Brice Arnold
- Despina Milathianaki
- Eduardo Granados
- Emma
- Eric Galtier
- Gary Bouchard
- Glenzer
- Greg Hays
- Gregori
- Guillot
- Hae Ja Lee
- Hoarty
- James Young
- Jensen
- Jerry Hastings
- Jing Yin
- Justin Garofoli
- Kalantar
- Kritcher
- Landen
- Lee
- Lori Plummer
- Loveridge-Smith
- Maiden
- Marc Campell
- Marc Welch
- Milathianaki
- Minitti
- Mondal
- Murnane
- Murphy
- Philip Heimann
- Richard F. Boyce
- Richard M. Boyce
- Richard W. Lee
- Rodenburg
- Ruben Curiel
- Schropp
- Schropp
- Schropp
- Schropp
- Suggit
- Tabak
- Thibault
- Ulf Zastrau
- William White
- Zhou Xing
- Publication venue
- 'International Union of Crystallography (IUCr)'
- Publication date
- 01/01/2015
- Field of study
The LCLS beam provides revolutionary capabilities for studying the transient behavior of matter in extreme conditions. The particular strength of the Matter in Extreme Conditions instrument is that it combines the unique LCLS beam with high-power optical laser beams, and a suite of dedicated diagnostics tailored for this field of science. In this paper an overview of the beamline, the capabilities of the instrumentation, and selected highlights of experiments and commissioning results are presented
Individual Health Trainers to support health and wellbeing for people under community supervision in the criminal justice system: the STRENGTHEN pilot RCT
- Author
- Publication venue
- 'National Institute for Health Research'
- Publication date
- 16/05/2019
- Field of study
No embargo require
Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial
- Author
- Abano Nenette
- Abbdul-saheb Mudhar
- Adedoyin Temi
- Adell Victoria
- Adesina Tolu
- Adie Katja
- Adil-Smith Jennifer
- Ahmad Nasar
- Ahmed Ashraf
- Ahmed Iman
- Al-Mayhani Talal
- Al-Shahi Salman Rustam
- Al-Shahi Salman Rustam
- Alam Mohammad Irfan
- Albazzaz Mo
- Ali Ali
- Alipio Francis
- Allen Christopher
- Allison Joanna
- Amey Isobel
- Amis Elaine
- Amlani Sageet
- Amoils Shannon
- Amor Kelly
- Anderson Rosemary
- Andole Sreeman
- Anjum Talat
- Ankolekar Sandeep
- Annamalai Arunkumar
- Anthony Alpha
- Anversha Ajmal
- Anwar Ijaz
- Anwar Sajjad
- Appleton Jason
- Argandona Lucia
- Armitage Jane
- Ashton Amy
- Atkinson Natalie
- Auld Grace
- Avis Joanne
- Aweid Basaam
- Ayres Georgina
- Azhar Khalid
- Bagnall Caroline
- Baig Farrukh
- Baigent Colin
- Bailey Duncan
- Baird Yolanda
- Bakawala Rehana
- Baker John
- Baker Pauline
- Balazikova Olga
- Balian Linda
- Baliga Vidya
- Balitska Olesia
- Ball Julie
- Ball Margaret
- Ballantine Robert
- Bamford John
- Banaras Azra
- Barber Mark
- Barbon Emma
- Barker James
- Barr Charlotte
- Barrie Elizabeth
- Barron Luke
- Barry Adrian
- Bateman Gavin
- Bates Michelle
- Bathula Rajaram
- Battersby-Wood Emma
- Bayliss Pauline
- Beadle Hannah
- Bearne Helen
- Beaty Teresa
- Beaves Emily
- Bell Angela
- Bell Jo
- Bell Murdina
- Bellfield Ruth
- Beranova Eva
- Bergin Adrian
- Bhakri Harbens
- Bhalla Ajay
- Bharaj Kiranjit
- Bhargava Maneesh
- Bhaskaran Biju
- Bhatnagar Priya
- Bhatnagar Priya
- Birchall Kathryn
- Birns Jonathan
- Black Toby
- Blades Alex
- Blair Caroline
- Blair Caroline
- Blair Gordon
- Blane Sujata
- Blank Catrin
- Blight Adrian
- Board Joanne
- Board Sarah
- Bokhari Maria
- Bond Kirsty
- Bowring Angela
- Boxall Cherish
- Breeds Joanna
- Brew Helen
- Brezitski Maria
- Bridger Hayley
- Brodie Fiona
- Brotherton Lucy
- Broughton David
- Brown Claire
- Brown Ellen
- Brown Pauline
- Brown Sarah
- Bruce David
- Buchanan David
- Buck Amanda
- Buckle Steve
- Buckle Steve
- Buckley Clare
- Bunea George
- Burger Ilse
- Burgess Laura
- Burgess Seona
- Burssens Evelyne
- Butler Adrian
- Butler Donna
- Butler Rebecca
- Butterworth-Cowin Nicola
- Button Denise
- Buxton Jean
- Byrne Anthony
- Cageao Julie
- Caine Sarah
- Campbell Robert
- Carpenter Michael
- Carpio Racquel
- Carrie Johanna
- Cassidy Tim
- Causley Chelsea
- Chadbourn Indra
- Chadha Dinesh
- Chamberlain Angela
- Chan kelly
- Chandrakumar Aberami
- Chapman Kath
- Chapman Nicola
- Charles Bethan
- Chatterjee Kausic
- Chaudhry Afnan
- Chauhan Meena
- Chenna Srikanth
- Cherian Suja
- Cheripelli Bharath Kumar
- Chopra Neha
- Choulerton James
- Choy Lillian
- Clarke Brian
- Clarke Caroline
- Clarke Judith
- Clarke Natasha
- Clarke Rebecca
- Clarke Samantha
- Clarkson Emma
- Clay Caroline
- Clayton Susan
- Clayton-Evans Lisa
- Cluckie Gillian
- Cochrane Helen
- Codd Laura
- Cohen David
- Collins Kayleigh
- Connor Lynda
- Constantin Carmen
- Cook Angela
- Cooper Martin
- Copeland Claire
- Cosier Tracey
- Courtauld Gillian
- Couser Mandy
- Coward Lucy
- Cowie Linda
- Cox Chantel
- Cox Chloe
- Cox Penelope
- Crabtree Karen
- Crawford Pam
- Crawford Susan
- Creeden Robyn
- Crisp Sarah
- Cronin Julie
- Crook Luci
- Crosbie Caroline
- Crouch Nichola
- Crown Rachel
- Crowther Hannah
- Cuddy Sarah
- Cuenoud Larissa
- Cullen Claire
- Culmsee Charlotte
- Cunningham James
- Cunningham Mishell
- Cvoro Vera
- Dacey Lynne
- Dakin Katy
- Dallol Bander
- Dangri Puneet
- Datta Prabal
- Davey Richard
- David Anette
- David Owen
- Davies Caroline
- Davies Ruth
- Davies Silvie
- Davis Fiona
- Davis Michelle
- Day Nicola
- Dayal Nilofer
- De Berker Henry
- Deary Ann
- Denic Hayley
- Dennis Martin
- Dennis Martin S
- Denniss Carol
- Devine Joseph
- Devitt Nicola
- Dewar Richard
- Dhakal Mahesh
- Dhar Saikat
- Dickinson Christina
- Dickson Christine
- Dima Sofia
- Dinsmore Lynn
- Dixon Lynn
- Dobson Tracey
- Dodd Angela
- Dodd Emily
- Doherty Mandy
- Doherty Mandy
- Donaldson Denise
- Donnelly Richard
- Doubal Fergus
- Dow Lindsey
- Downham Susan
- Doyle Clare
- Doyle Donna
- Drever Jonathan
- du Plessis Johann C
- du Plessis Johannes
- Dube Judith
- Duberley Stephen
- Dunn Linda
- Dunne Karen
- Durairaj Ramesh
- Durman Helen
- Dutta Dipankar
- Dynan Kevin
- Edwards Mandy
- Egerton Shuna
- Eglinton Charlotte
- Eglinton Charlotte
- El Tawil Salwa
- Elfandi Khaled
- Elliot Jennifer
- Elliott Emma
- Ellis Sam
- Emberson Jonathan
- Emsley Hedley
- England Timothy
- Epstein Daniel
- Erande Renuka
- Erumere Esther
- Esisi Bernard
- Esisi Bernard
- Esson Derek
- Esson Derek
- Evans Rachel
- Evans Sue
- Eveson David
- Ewing Jordan
- Fathima Razik
- Fawcett Michelle
- Feerick Shez
- Fennelly Ruth
- Ferdinand Phillip
- Findlay Paul
- Finlay Sarah
- Finney Kay
- Fitzell Pauline
- Fitzsimmons Paul
- Fletcher Glyn
- Fletcher Jo
- Fong Rosanna
- Foot Jayne
- Foote Leanne
- Ford Gary
- Foster Eliza
- Fotherby Ken
- Fox Charlotte
- Francia Nina
- Francis Jobbin
- Fraser Ruth
- Fraser Ruth
- Fuller Tracy
- Fulton Ailsa
- Furnace Jacqueline
- Gadapa Naveen
- Gainard Glyn
- Gainsborough Nicola
- Gallagher Jill
- Gallagher Louise
- Gallifent Rachel
- Gamble Ed
- Garcia Tatiana
- Gardener Léjeune
- Garfield-Smith Joanne
- Garside Mark
- Gartrell Imogen
- Gascoyne Rachel
- Gattringer Thomas
- Gautam Nikki
- Gaylard Jane
- Gbadamoshi Lukuman
- Geraghty Olivia
- Ghaly George
- Ghatala Rita
- Ghosh Sandip
- Giallombardo Elio
- Gilham Ellie
- Gilmour Danielle
- Gilzeane Nicola
- Glass Jon
- Gleave Laura
- Glover Rachel
- Godfrey Margi
- Goff Anita
- Goorah Neetish
- Gott Valerie
- Gow Heather
- Graham Carol
- Graham Ruth
- Gray Jane
- Green Carole
- Greenwood Richard
- Gregory Bindu
- Greig Jill
- Grimwood Gemma
- Grocott Jeanette
- Grue Rebecca
- Gulliver Diane
- Guo Fenglin
- Gupwell Karin
- Guthrie Lucy Belle
- Guy Helen
- Guyler Paul
- Hague Adam
- Haider Syed
- Hairsine Brigid
- Hakim Eluzai
- Hall Andrea
- Halse Omid
- Handley Dominic
- Hann Gail
- Hannon Niamh
- Hansen Christian
- Haque Mohammad
- Hardwick Anne
- Harkness Kirsty
- Harrington Frances
- Harrington-Davies Yasmin
- Harrison Louise
- Harrison Melanie
- Harrison Thomas
- Harston George
- Harvey Kirsten
- Harvey Miriam
- Hassan Ahamad
- Hassan Hardi
- Havard Diane
- Hayes Anne
- Hayhoe Helen
- Hayman Rachel
- Hays Carole
- Hazel Beth
- Hedstrom Amanda
- Hedstrom Amanda
- Hemsley Anthony
- Henry Margo
- Herman Jane
- Hervey Simon
- Hewitt Jonathan
- Hiden Joanne
- Hogan Caroline
- Hogg Valerie
- Holden Melinda
- Holmes Clare
- Homan Jane
- Hooley Michaela
- Horan Kathleen
- Horton Sarah
- Hostettler Isabel
- Hove Dionne
- Howaniec Laura
- Howard Gabriella
- Howard Joanne
- Howard Peter
- Howcroft Deborah
- Howe Jo
- Huang Xuya
- Huggett Isabel
- Hughes Chloe
- Hughes Claire
- Hughes Tom
- Humphreys Louise
- Humphries Fiona
- Hunt Benjamin
- Hunt Nicholas
- Hunter Annemarie
- Hunter Neil
- Hurford Frances
- Hurley Jennifer
- Hussain Malik
- Hutchison Aidan
- Hyams Benjamin
- Hyatt Lisa
- Imam Javed
- Ingham Andrea
- Ingram Tanya
- Innes Karen
- Iqbal Arshi
- Iqbal Mohammad Shazad
- Irvine Janice
- Ispoglou Sissy
- Ivatts Simone
- Jackson Benjamin
- Jackson Linda
- Jagger Jenny
- Jagpal Baljit
- James Ali
- James Claire
- James Martin
- Jarapa Rowilson
- Jarrett David
- Jeffs Carol
- Jelley Benjamin
- Jenkins Colin
- Jennings-Preece Karla
- Jeyaraj Naomi
- Jha Ratneshwari
- Jinks Emma
- Johnes Mary
- Johnson Sharon
- Jones Ifan
- Jones Ifan
- Jones Kirsty
- Jones Rachael
- Jones Stephanie
- Jones Terry
- Jones Val
- Jordan Carla
- Jose Deepa
- Jose Josin
- Joshi Yogish
- Joshi Yogish
- Joyson Anu
- Jupp Becky
- Justin Frances
- Kakar Puneet
- Kalathil Latheef
- Kalladka Dheeraj
- Kamara Christine
- Kambafwile Mary
- Kane Ingrid
- Kar Arindam
- Keegan Breffni
- Keeling Elizabeth
- Keenan Samantha
- Kelavkar Shyam
- Kelly Christine
- Kelly Debs
- Kelly Jim
- Kelly Siobhan
- Keltos Marketa
- Kennedy James
- Kennedy Kate
- Kenton Antony
- Kerin Lourda
- Kerr Enda
- Kerr Gillian
- Keshvara Rekha
- Khan Mohammad
- Khan Shagufta
- Khan Usman
- Khan Uzma
- Kibutu Faith
- King Sam
- Kingwell Hayley
- Kini Manohar
- Klaasen Katrina
- Knops Kerstin
- Krishnamoorthy Shrivakumar
- Krishnamurthy Ramesh
- Krishnamurthy Vinodh
- Krishnan Kailash
- Krishnan Manju
- Krommyda Magdalini
- Kullane Sagal
- Kumar Balakrishna
- Kumar Pradeep
- Kunhunny Swapna
- Lam Man Yee
- Lambert Caroline
- Landers Geraldine
- Langhorne Peter
- Lasserson Daniel
- Latter Laura
- Law Zhe
- Lawrence Tara
- Lawson Heidi
- Leason Sandra
- Lee Stephanie
- Leggett Jacqui
- Lenti Giulia
- Lerpiniere Christine
- Lerpiniere Christine
- Licenik Radim
- Lindert Ralf
- Little Victoria
- Littleton Edward
- Ljubez Anja
- Loganathan Thayalini
- Longland Barbara
- Lopez Paula
- Lovelock Caroline
- Lowe Gordon
- Lucas Linda
- Lucas Suzanne
- Luder Robert
- Lyjko Sue
- Maanoosi Mehran
- Maatouk Ahmad
- Macaden Ashish
- MacInnes Brian
- MacLennan Beverly
- Macleod Malcolm
- MacLeod Mary
- MacLiver Linda
- MacRaild Allan
- Maddula Mohana
- Madigan Barbara
- Maguire Holly
- Maguire Stuart
- Maiden Susan
- Majis Arshad
- Majmudar Nikhil
- Makawa Linetty
- Mangion David
- Manning Lisa
- Manoj Aravind
- Mardania Rina
- Marigold James Richard
- Markova Skarlet
- Marks Katherine
- Marsden Tracy
- Marshall Sally
- Martin Irene
- Mashate Sheila
- Mason Cathy
- Mate Abhijit
- Mathieson Philip
- Matias Oliver
- Matthews Christopher
- Maund Bev
- McAlpine Christine
- McArdle Damian
- Mcauley Sean
- McCann Stephanie
- McCarron Mark
- McClelland Beverley
- McCormick Katrina
- McCormick Katrina
- McDonald Shanni
- McDonald Susan
- Mcgee Joanne
- McGhee Caroline
- McGill Connor
- McGrath Aileen
- McIlmoyle James
- McKee Jacqueline
- McLoughlin Alison
- McVerry Ferghal
- Mead Denise
- Mead Gillian
- Meir Julie
- Menon Nisha
- Mercer Lily
- Metcalf Kneale
- Miller Keniesha
- Miller Richard
- Milligan Josette
- Minks David
- Minks David P.
- Miriam Skelton
- Mistri Amit
- Mitchell Jennifer
- Mitra Dipayan
- Mitra Dipayan
- Mohammed Niaz
- Mohd Nor Azlisham
- Mokoena Betty
- Moores Andrew
- Moqsith Mohammed
- Morell Jordi
- Moreton Fiona
- Morgan Debbie
- Moroney Helen
- Morse Bethan
- Moseley Sally
- Motherwell Nichola
- Moynihan Barry
- Mpelembue Mushiya
- Mudd Paul
- Muddegowda Girish
- Muir Keith
- Mukherjee Indranil
- Murali Elodie
- Murphy Peter
- Murray Gordon D
- Musarrat Kashif
- Myint Min
- Naeem Muhammad
- Naing Zin
- Nair Anand
- Nallasivan Arumugam
- Nasar Mohammad
- Nasim Ashraf
- Naylor Charde
- Needle Ann
- Nelson Sandra
- Newby David E
- Newton Sophie
- Ng Kheng Xiong
- Ngo David
- Nguyen Vinh
- Ngwako Mmua
- Ni Hlaing
- Nicholas Paul
- Nicolson Anne
- Niranchanan Rangah
- Nisar Nabeela
- Njoku Kelechi
- Nott Claire
- Nott Claire
- Nozedar Tarn
- Nyabadza Sheila
- O'Brien Eoin
- O'Brien Richard
- O'Brien Richard
- O'Connell Susan
- O'Loughlin Victoria
- O'Reilly Joanna
- O'Toole Sarah
- OConnell Janice
- Oji Nnebuife
- Orath Prabakaran Rajalakshmi
- Orefo Chukwuka
- Orugun Enoch
- Osborn Mairead
- Osborne Emily
- Oshodi Anne
- Osman Ahmed
- Ovington Catherine
- Owings Paula
- Owoyele Emmanuelle
- Owusu-Agyei Peter
- Pai Yogish
- Palmer Jeb
- Papavasileiou Vasileios
- Parakramawansha Ruwan
- Parker Richard
- Parry Anthea
- Parry-Jones Adrian
- Pasco Kath
- Patel Bhavini
- Patel Champa
- Patel Farzana
- Patel Krishna
- Patterson Chris
- Paulton Ruth
- Pawley Corinne
- Peixoto Cassilda
- Penge Justin
- Perez Jane
- Perfitt Rebekah
- Perkins Charlotte
- Perry David
- Perry Jack
- Persad Nicola
- Peters Jenny
- Pettitt Kerry
- Phiri Duke
- Pitt-Ford Alexandra
- Pitt-Kerby Tressy
- Plewa Catherine
- Poku Philip
- Ponnambath Suheil
- Poultney Una
- Pound Susan
- Power Michael
- Pressly Vanessa
- Price Fiona
- Proeschel Harald
- Punekar Shuja
- Punter Martin
- Pusalkar Aparna
- Putterill Janet
- Quinn Leanne
- Quinn Outi
- Qureshi Sammie
- Ragab Suzanne
- Raghunathan Senthil
- Rahman Bithi
- Rai Baljinder
- Raj Sonia
- Rajapakse Anoja
- Rajkumar Chakravarthi
- Ramachandran Sankaranarayana
- Ramadan Hawraman
- Ramshaw Alex
- Rana Pratap
- Randall Marc
- Rashed Khalid
- Rashmi Sindhu
- Ravenhill Garth
- Rayessa Rayessa
- Reckless Ian
- Reddan Julie
- Reddan Julie
- Redgrave Jessica
- Redjep Ozlem
- Remegoso Alda
- Richard Bella
- Richards Emma
- Rinkel Gabriel
- Roberts Josh
- Robinson Matthew
- Robinson Naomi
- Rodgers Alicia
- Rodrigues Mark A
- Rodriguez Aryelly
- Roffe Christine
- Roffe Jack
- Roganova Tatjana
- Rogers Emily
- Rogers Gill
- Rojas Javier
- Ross Sarah
- Roughan Caroline
- Rudd Tony
- Rudenko Hannah
- Saada Janak
- Saastamoinen Kari
- Sajid Mahmud
- Sakka Eleni
- Salehin Maqsud
- Salek-Haddadi Afraim
- Salih Isam
- Sally Moore
- Sandercock Peter A G
- Sangombe Mirriam
- Sangster Graeme
- Sanyal Ranjan
- Sarah Procter
- Sarah Procter
- Sattar Naweed
- Sattar Saira
- Saulat Afaq
- Saulat Afaq
- Schofield Christine
- Schulz Ursula
- Schumacher Natasha
- Schwarz Stefan
- Seagrave Samantha
- Sekaran Lakshmanan
- Sesay Juliana
- Sethuraman Sakthivel
- Shackcloth Daniela
- Shah Alex
- Shah Sweni
- Shahmehri Shahrzad
- Sharma Nikhil
- Sharpe Simon
- Shaw Kelly Marie
- Shaw Louise
- Sheikh Saima
- Shekhar Raj
- Shelton Faye
- Shinh Naval
- Shread Ian
- Shukla Avani
- Siddegowda Prasad
- Siddiq Muhammad
- Siddiqui Amber
- Siddiqui Anwer
- Sigsworth Andrew
- Simon Rohan
- Sims Don
- Singh Arun
- Sinha Devesh
- Skinner Helen
- Slade Peter
- Smart Amanda
- Smith Andrew
- Smith Fiona
- Smith Gemma Marie
- Smith Simon
- Smith Wilma
- Smyth Nigel
- Spencer Jayne
- Sprigg Nikola
- Sprigg Nikola
- Srinivasan Meena
- Stafford Samantha
- Stafford Samantha
- Stanners Andrew
- Steele Amy
- Stephen Jacqueline
- Stephens Claire
- Stevens Angela
- Stevens Stephanie
- Stevenson Sarah
- Stewart Kelvin
- Stocks Kathy
- Stone Andrew
- Storton Sharon
- Strain David
- Subramonian Santhosh
- Sudlow Cathie
- Sudlow Cathie L M
- Sukdeo Varthi
- Sullivan Frank
- Sultan Sulaiman
- Suttling Anne
- Sutton Claire
- Sutton Patrick
- Sutton Victoria
- Sword Jane
- Sykes Lucy
- Symonds Stuart
- Szabo Susan
- Tallantyre Emma
- Tanate Alfonso
- Tandy Jane
- Tate Margaret
- Tauro Suzanne
- Tayler Michelle
- Taylor Pat
- Taylor Vicky
- Teal Rachel
- Temple Natalie
- Thant Hlaing
- Thavanesan Kamy
- Thomas Isobel
- Thomas Kelly
- Thomas Philip
- Thomas Sarah
- Thompson Philip
- Thompson Susan
- Thompson Teresa
- Thompson-Jones Helen
- Thomson Audrey
- Thornthwaite Sarah
- Thorpe Kevin
- Tilley Victoria
- Tiwari Divya
- Tomlin Dawn
- Tomlinson Benjamin
- Treadwell Shelley
- Tribbeck Michele
- Trippier Sarah
- Triscott Claire
- Triscott Claire
- Tryambake Dinesh
- Tucker Laura
- Tucker Susan
- Turfrey Jennifer
- Tysoe Sharon
- Ullah Khalil
- Valentine Stacey
- van Someren Chloe
- Varquez Resti
- Vasileiadis Evangelos
- Vassallo Joseph
- Venter Marius
- Veraque Emelda
- Verrion Anna
- Vettimootal Johnson Venetia
- Vickers Carinna
- Walford Jamie
- Walker Allan
- Walker Marion
- Walker Pauli
- Walker Susannah
- Wallace Aine
- Wallace Rebecca
- Wallace Rebecca
- Walstow Deborah
- Walter Deborah
- Walters Ashleigh
- Wani Mushtaq
- Ward Deborah
- Wardlaw Joanna M
- Watchurst Caroline
- Waterfield Kelly
- Waterfield Kelly
- Watson Fran
- Waugh Dean
- Webb Tom
- Webber Adam
- Webster Timothy
- Weinling Marie
- Weir Nic
- Weir Pauline
- Welch Angela
- Werring David
- Werring David J
- Whitcher Alison
- White James
- White Julie
- White Philip M
- White Susan
- Whiteley William
- Whiteley William N
- Whiteman Jessica
- Whiteman Jessica
- Whiting Robert
- Whittamore Katherine
- Wiggam Ivan
- Wilding Peter
- Wilkes Gwendoline
- Wilkinson Mark
- Willberry Angela
- Williams Carol
- Williams Rebecca
- Williams-Yesson Barbara
- Willmot Mark
- Wilson David
- Wilson Duncan
- Wilson Jenny
- Wilson Lisa
- Wilson Sarah
- Wiltshire Alison
- Wood Diane
- Wood Edith
- Wood Lisa
- Woodward Stephen
- Wright Fiona
- Wroath Belinda
- Wynter Inez
- Yadava Rajendra
- Yip Brigitte
- Young Andrew
- Zachariah George
- Zahoor Tajammal
- Zoe Mellor
- Publication venue
- 'Elsevier BV'
- Publication date
- 22/05/2019
- Field of study
Background
Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features modify the effects of antiplatelet therapy
Erratum to: Methods for evaluating medical tests and biomarkers
- Author
- Gowri Gopalakrishna
- null null
- Miranda Langendam
- Rob Scholten
- Patrick Bossuyt
- Mariska Leeflang
- Anna Noel-Storr
- James Thomas
- Iain Marshall
- Byron Wallace
- Penny Whiting
- Clare Davenport
- Mariska Leeflang
- Gowri GopalaKrishna
- Isabel de Salis
- Sue Mallett
- Robert Wolff
- Penny Whiting
- Richard Riley
- Marie Westwood
- Jos Kleinen
- Gary Collins
- Hans Reitsma
- Karel Moons
- Antonia Zapf
- Annika Hoyer
- Katharina Kramer
- Oliver Kuss
- J. Ensor
- J. J. Deeks
- E. C. Martin
- R. D. Riley
- Gerta Rücker
- Susanne Steinhauser
- Martin Schumacher
- Richard Riley
- Joie Ensor
- Kym Snell
- Brian Willis
- Thomas Debray
- Karel Moons
- Jon Deeks
- Gary Collins
- Lavinia Ferrante di Ruffano
- Brian Willis
- Clare Davenport
- Sue Mallett
- Sian Taylor-Phillips
- Chris Hyde
- Jon Deeks
- Sue Mallett
- Stuart A. Taylor
- Gauraang Batnagar
- Sian Taylor-Phillips
- Lavinia Ferrante Di Ruffano
- Farah Seedat
- Aileen Clarke
- Jon Deeks
- Sarah Byron
- Frances Nixon
- Rebecca Albrow
- Thomas Walker
- Carla Deakin
- Chris Hyde
- Zhivko Zhelev
- Harriet Hunt
- Lavinia Ferrante di Ruffano
- Yaling Yang
- Lucy Abel
- James Buchanan
- Thomas Fanshawe
- Bethany Shinkins
- Laure Wynants
- Jan Verbakel
- Sabine Van Huffel
- Dirk Timmerman
- Ben Van Calster
- Mariska Leeflang
- Aeliko Zwinderman
- Patrick Bossuyt
- Jason Oke
- Jack O’Sullivan
- Rafael Perera
- Brian Nicholson
- Hannah L. Bromley
- Tracy E. Roberts
- Adele Francis
- Denniis Petrie
- G. Bruce Mann
- Kinga Malottki
- Holly Smith
- Jon Deeks
- Lucinda Billingham
- Alice Sitch
- Sue Mallett
- Jon Deeks
- Oke Gerke
- Mie Holm-Vilstrup
- Eivind Antonsen Segtnan
- Ulrich Halekoh
- Poul Flemming Høilund-Carlsen
- Bernard G. Francq
- Jon Deeks
- Alice Sitch
- Jac Dinnes
- Julie Parkes
- Walter Gregory
- Jenny Hewison
- Doug Altman
- William Rosenberg
- Peter Selby
- Julien Asselineau
- Paul Perez
- Aïssatou Paye
- Emilie Bessede
- Cécile Proust-Lima
- Christiana Naaktgeboren
- Joris de Groot
- Anne Rutjes
- Patrick Bossuyt
- Johannes Reitsma
- Karel Moons
- Gary Collins
- Emmanuel Ogundimu
- Jonathan Cook
- Yannick Le Manach
- Doug Altman
- Laure Wynants
- Yvonne Vergouwe
- Sabine Van Huffel
- Dirk Timmerman
- Ben Van Calster
- Romin Pajouheshnia
- Rolf Groenwold
- Karen Moons
- Johannes Reitsma
- Linda Peelen
- Ben Van Calster
- Daan Nieboer
- Yvonne Vergouwe
- Bavo De Cock
- Micael J. Pencina
- Ewout W. Steyerberg
- Jennifer Cooper
- Sian Taylor-Phillips
- Nick Parsons
- Chris Stinton
- Steve Smith
- Andy Dickens
- Rachel Jordan
- Alexandra Enocson
- David Fitzmaurice
- Alice Sitch
- Peymane Adab
- Bernard G. Francq
- Charles Boachie
- Gaj Vidmar
- Karoline Freeman
- Martin Connock
- Sian Taylor-Phillips
- Rachel Court
- Aileen Clarke
- Joris de Groot
- Christiana Naaktgeboren
- Hans Reitsma
- Carl Moons
- Jessica Harris
- Andrew Mumford
- Zoe Plummer
- Kurtis Lee
- Barnaby Reeves
- Chris Rogers
- Veerle Verheyden
- Gianni D. Angelini
- Gavin J. Murphy
- Jeremy Huddy
- Melody Ni
- Katherine Good
- Graham Cooke
- Patrick Bossuyt
- George Hanna
- Jie Ma
- Doug Altman
- Gary Collins
- K. G. M. Moons
- Joris A. H. de Groot
- Sue Mallett
- Doug G. Altman
- Johannes B. Reitsma
- Gary S. Collins
- Karel G. M. Moons
- Douglas G. Altman
- Johannes B. Reitsma
- Gary S. Collins
- Adina Najwa Kamarudin
- Ruwanthi Kolamunnage-Dona
- Trevor Cox
- Melody Ni
- Jeremy Huddy
- Simone Borsci
- George Hanna
- Teresa Pérez
- M.Carmen Pardo
- Angel Candela-Toha
- Alfonso Muriel
- Javier Zamora
- Sabina Sanghera
- Syed Mohiuddin
- Richard Martin
- Jenny Donovan
- Joanna Coast
- Mikyung Kelly Seo
- John Cairns
- Elizabeth Mitchell
- Alison Smith
- Judy Wright
- Peter Hall
- Michael Messenger
- Nicola Calder
- Nyantara Wickramasekera
- Karen Vinall-Collier
- Andrew Lewington
- Romin Pajouheshnia
- Johanna Damen
- Rolf Groenwold
- Karel Moons
- Linda Peelen
- Michael Messenger
- David Cairns
- Alison Smith
- Michelle Hutchinson
- Judy Wright
- Peter Hall
- Nicola Calder
- Cathie Sturgeon
- Liz Mitchel
- Rebecca Kift
- Sofia Christakoudi
- Manohursingh Rungall
- Paula Mobillo
- Rosa Montero
- Tjir-Li Tsui
- Sui Phin Kon
- Beatriz Tucker
- Steven Sacks
- Chris Farmer
- Terry Strom
- Paramit Chowdhury
- Irene Rebollo-Mesa
- Maria Hernandez-Fuentes
- Johanna A. A. G. Damen
- Thomas P. A. Debray
- Pauline Heus
- Lotty Hooft
- Karel G. M. Moons
- Romin Pajouheshnia
- Johannes B. Reitsma
- Rob J. P. M. Scholten
- Johanna A. A. G. Damen
- Lotty Hooft
- Ewoud Schuit
- Thomas P. A. Debray
- Gary S. Collins
- Ioanna Tzoulaki
- Camille M. Lassale
- George C. M. Siontis
- Virginia Chiocchia
- Corran Roberts
- Michael Maia Schlüssel
- Stephen Gerry
- James A. Black
- Pauline Heus
- Yvonne T. van der Schouw
- Linda M. Peelen
- Karel G. M. Moons
- Johanna A. A. G. Damen
- Thomas P. A. Debray
- Pauline Heus
- Lotty Hooft
- Karel G. M. Moons
- Romin Pajouheshnia
- Johannes B. Reitsma
- Rob J. P. M. Scholten
- Jie Ma
- Doug Altman
- Gary Collins
- Graeme Spence
- David McCartney
- Ann van den Bruel
- Daniel Lasserson
- Gail Hayward
- Werner Vach
- Antoinette de Jong
- Coreline Burggraaff
- Otto Hoekstra
- Josée Zijlstra
- Henrica de Vet
- Harriet Hunt
- Chris Hyde
- Sara Graziadio
- Joy Allen
- Louise Johnston
- Rachel O’Leary
- Michael Power
- Joy Allen
- Sara Graziadio
- Louise Johnson
- Rachel O’Leary
- Michael Power
- Ray Waters
- John Simpson
- Louise Johnston
- Joy Allen
- Sara Graziadio
- Rachel O’Leary
- Ray Waters
- Michael Power
- Sue Mallett
- Thomas R. Fanshawe
- Peter Phillips
- Andrew Plumb
- Emma Helbren
- Steve Halligan
- Stuart A. Taylor
- Alastair Gale
- Sue Mallett
- Peggy Sekula
- Douglas G. Altman
- Willi Sauerbrei
- Sue Mallett
- Thomas R. Fanshawe
- Julia R. Forman
- Susan J. Dutton
- Yemisi Takwoingi
- Elizabeth M. Hensor
- Thomas E. Nichols
- Bethany Shinkins
- Yaling Yang
- Lucy Abel
- Lavinia Ferrante Di Ruffano
- Thomas Fanshawe
- Emmanuelle Kempf
- Raphael Porcher
- Jennifer de Beyer
- Karel Moons
- Douglas Altman
- Hans Reitsma
- Sally Hopewell
- Willi Sauerbrei
- Gary Collins
- John Dennis
- Beverley Shields
- Angus Jones
- William Henley
- Ewan Pearson
- Andrew Hattersley
- Pauline Heus
- Johanna A. A. G. Damen
- Romin Pajouheshnia
- Rob J. P. M. Scholten
- Johannes B. Reitsma
- Gary S. Collins
- Douglas G. Altman
- Karel G. M. Moons
- Lotty Hooft
- Beverley Shields
- John Dennis
- Angus Jones
- William Henley
- Ewan Pearson
- Andrew Hattersley
- Fueloep Scheibler
- Anne Rummer
- Sibylle Sturtz
- Robert Großelfinger
- Katie Banister
- Craig Ramsay
- Augusto Azuara-Blanco
- Jonathan Cook
- Charles Boachie
- Jennifer Burr
- Manjula Kumarasamy
- Rupert Bourne
- Ijeoma Uchegbu
- Simone Borsci
- Jennifer Murphy
- George Hanna
- Ijeoma Uchegbu
- Alex Carter
- Jen Murphy
- Melody Ni
- Joachim Marti
- Julie Eatock
- Ijeoma Uchegbu
- Julie Robotham
- Maria Dudareva
- Mark Gilchrist
- Alison Holmes
- Ijeoma Uchegbu
- Simone Borsci
- Phillip Monaghan
- Sarah Lord
- Andrew StJohn
- Sverre Sandberg
- Christa Cobbaert
- Lieselotte Lennartz
- Wilma Verhagen-Kamerbeek
- Christoph Ebert
- Patrick Bossuyt
- Andrea Horvath
- Kevin Jenniskens
- Christiana Naaktgeboren
- Johannes Reitsma
- Karel Moons
- Joris de Groot
- Chris Hyde
- Jaime Peters
- Bogdan Grigore
- Jaime Peters
- Chris Hyde
- Chris Hyde
- Obi Ukoumunne
- Jaime Peters
- Zhivko Zhelev
- Brooke Levis
- Andrea Benedetti
- Alexander W. Levis
- John P. A. Ioannidis
- Ian Shrier
- Pim Cuijpers
- Simon Gilbody
- Lorie A. Kloda
- Dean McMillan
- Scott B Patten
- Russell J. Steele
- Roy C Ziegelstein
- Charles H. Bombardier
- Flavia de Lima Osório
- Jesse R. Fann
- Dwenda Gjerdingen
- Femke Lamers
- Manote Lotrakul
- Sonia R Loureiro
- Bernd Löwe
- Juwita Shaaban
- Lesley Stafford
- Henk C. P. M. van Weert
- Mary A. Whooley
- Linda S. Williams
- Karin A. Wittkampf
- Albert S. Yeung
- Brett D. Thombs
- Jaime Peters
- Chris Cooper
- James Buchanan
- Tom Nieto
- Claire Smith
- Olga Tucker
- Janine Dretzke
- Andrew Beggs
- Nirmala Rai
- Clare Davenport
- Sue Bayliss
- Simon Stevens
- Kym Snell
- Sue Mallet
- Jon Deeks
- Sudha Sundar
- Emma Hall
- Nuria Porta
- David Lorente Estelles
- Johann de Bono
- null null
- null null
- null null
- null null
- null null
- null null
- Publication venue
- Springer Nature
- Publication date
- 01/01/2003
- Field of study
[This corrects the article DOI: 10.1186/s41512-016-0001-y.]
The development and validation of a scoring tool to predict the operative duration of elective laparoscopic cholecystectomy
- Author
- Aawsaj Yousif
- Abayomi Michael
- Acharya Vikas
- Aggarwal Smeer Kumar
- Ahmad Anwar
- Ahmed Irfan
- Ahmed Jamil
- Ahmed Javed
- Ahmed Talat
- Ainley Paul
- Akhtar Mansoor
- Al Amari Khalid
- Al-Abed Yahya A.
- Al-Akash Musallam
- Al-Bahrani Ahmed Z.
- Al-Khyatt Waleed
- Al-Muhktar Ahmed
- Al-Sarireh Bilal
- Al-Taan Omer
- Alagaratnam Swethan
- Alam Imran
- Alberts Justin
- Alderson Derek
- Aldridge Roland C.
- Aleksandrov Danail
- Ali Haythem
- Ali Shahda
- Amin Khalid
- Andrew David R.
- Appleton Shaun
- Arhi Chanpreet
- Aroori Somaiah
- Aryal Kamal
- Asad Mehek
- Aseem Rabiya
- Asprou Fotini M.
- Awan Altaf
- Ayaani Soofiyah
- Aymon null
- Babu Benoy I.
- Bajwa Dalvir S.
- Bajwa Farrukh M.
- Baker Andrew L.
- Balfe Paul
- Ball William R.
- Ballance Laura
- Banwell Victoria
- Barnes James
- Barrie Jenifer
- Bartlett Francis
- Basheer Mohammed
- Bashir Gareth
- Basra Melvinder
- Basu Sanjoy
- Basynat Pradeep
- Batt Jeremy
- Bausbacher Harald
- Bawa Sadiq
- Beasley William D.
- Belding Rowena
- Bellini Maria Irene
- Bennett Stephen P.
- Bhandari Santosh
- Bharamgoudar Reshma
- Bhattacharya Vish
- Blane Christine
- Blazeby Jane M.
- Boal Matthew
- Boddy Alexander
- Boland Michael
- Bond-Smith Giles
- Booth Michael I.
- Borowski David W.
- Bowen Laura
- Boyce Kathryn M.
- Boyd Alan T.
- Bradley Donal
- Bradley Neil
- Brennan Stephen
- Brett Daniel
- Broadhurst Jack
- Brooke Eleanor
- Brown Timothy H.
- Bryant Alice
- Buchan Joanna
- Bullen Naomi
- Bunnell Catherine
- Bunting David M.
- Burke Paul
- Byrne James P.
- Byrnes Colman K.
- Campbell William
- Carney Kate
- Carney Kate
- Carroll Paul
- Carter C. Ross
- Carter Nicholas C.
- Carty Nick
- Cassidy John T.
- Chambers Adam
- Chambers Alice
- Chambers Alice
- Chan Wei Ming
- Chang Jessica
- Charalabopoulos Alexandros
- Chauhan Neal
- Cheung Melanie
- Chhabra Alok
- Chishti Imran A.
- Chitre Vivek
- Choy Alfred
- Cieplucha Krzysztos
- Clements Joshua M.
- Coats Maria
- Cockbain Andrew J.
- Coe Peter O.
- Connelly Martin
- Cooke Fiachra
- Courtney Michael J.
- Cowley Jonathan B.
- Cross Keith S.
- Cuming Tamzin
- Cunha Pedro
- Dalgaty Faith
- Dar Farooq
- Date Ravindra
- Dave Rajiv V.
- Davey Phil
- Davies James
- Dawson Suzanne
- De Marchi Joshua A.
- de Siqueira Jonathan
- Deguara Jean
- Delisle Theo G.
- Dennison A. R.
- Derbyshire Laura
- Devoto Laurence
- Dhillon Ajit
- Diamond Tom
- Dickson-Lowe Richard
- Digney Ruairi
- Dindyal Shiva
- Dobbins Brian
- Doe Matthew
- Dorrian Emmet
- Doulias Triantafyllos
- Downing Justine
- Drake Benjamin
- Driscoll Peter J.
- Duke Diana
- Durkin Damien
- Dwerryhouse Simon J.
- D’Costa Conrad
- Ebdewi Hamdi
- Ebied Husam
- Eisawi Abdalla
- El-Dhuwaib Yesar
- El-Hasani Shamsi S.
- Elkheir Natalie
- Elmasry Mohamed
- Elsayed Mohammed
- Elshaer Mohamed
- Emesih Sophie
- Farag Sameh F.
- Farooq Ansar
- Farouk Marwan
- Fasih Tani
- Fawole Adeshina S.
- Fenwick Stephen
- Ferguson Graeme
- Ferris Paul
- Finch David
- Finch J. G.
- Finlay Ian
- Fleming Katie
- Fletcher Ted
- Fordham Imogen J.
- Forouzanfar Amir
- Forrest Craig R.
- Forster Luke
- Fothergill Laura
- Frame Richard J.
- Francombe James
- Frank Lucinda
- Fusai Guiseppe
- Galanopoulos Giorgios
- Gallagher Paul V.
- Garcea Giuseppe
- Gardner-Thorpe James
- Geoghegan Justin G.
- Geogloma Ileana
- Gerakopoulos Stratos
- Ghareeb Essam
- Ghazanfar Mudassar A.
- Gibson Simon
- Giles Mathew
- Giovinazzo Francesco
- Giwa Lola
- Goh Yan Li
- Gopalswamy Sivakumar
- Goscimski Andrzej
- Gossage James A.
- Gough Martin
- Gould Laura
- Gould Laura
- Grant Alan J.
- Gravante Gianpiero
- Griffiths Ewen
- Griffiths Ewen A.
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- Gurung Kabita
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- Hafiz Shazia
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- Hamady Zayed
- Hamdan Alhafidz
- Hamdan Mohammed F.
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- Hancorn Kate
- Haque Manzarul
- Haque Samer Ul
- Hardy Thomas J.
- Hargreaves Anita
- Harilingam Mohan
- Harris Andrew
- Harrison Ewen
- Hawkins Helen
- Heath Jonathan
- Hebbar Madhusoodhana
- Henderson Lucy T.
- Henley Natasha
- Heshaishi Mohamed
- Hewes James
- Hewes James C.
- Heywood Nick
- Higgs Simon M.
- Hill Arnold D. K.
- Hindley Caroline
- Hirst Natalie A.
- Hisham Elzanati
- Ho Wei-Min
- Hoban Jennifer R.
- Hodgkins Kathryn A.
- Hodson James
- Holroyd David J.
- Hooks Gareth
- Hopwood Benjamin
- Hornby Steve T.
- Hornsby Jane
- Hosie Kenneth B.
- Hosie Kenneth B.
- Hossack Martin R.
- Hossain Tanvir
- Hoti Emir
- Hou David
- Hrycaiczuk Alex
- Hughes Michael
- Hunter David I.
- Hussain Abdulzahra A.
- Hussain Adnan
- Hussain Anwar
- Hussain Najam
- Iftikhar Syed Yusuf
- Iqbal Nusrat
- Iskandar Edrin
- Issa Eyad
- Ivanovski Ivan
- Jackson Andrew
- Jackson Claire
- Jafferbhoy Sadaf F.
- Jambulingam Periyathambi
- Jamdar Saurabh
- Jamel Sara
- Janeczko Adam
- Jaunoo Shameen
- Jayanthi Naga V. G.
- Jelley Clare
- Jennings Neil A.
- Joel Abraham
- Johnpulle Michelle A.
- Johnston Dorothy
- Johnstone Marianne
- Johnstone Marianne
- Joji Nikita
- Jones Claire
- Jones Elinor
- Jones Gareth H.
- Jones M. Angharad
- Jones Michael J.
- Jones Robert P.
- Jones Steven M.
- Kadhim Abbas
- Kadirkamanathan Sritharan
- Kallaway Charlotte
- Kanakala Venkatesh
- Kanavati Osama
- Kansal Nisheeth
- Kaptanis Sarantos
- Karavadra Babu
- Karim Lawen
- Karunakaran Priyadarssini
- Kaur Parminder
- Kausar Ambareen
- Kelly Michael E.
- Kendal Chris
- Kennedy David
- Kenny Ross
- Keogh Ken
- Khalil Ahmed M.
- Khan Amarah
- Khan Mohammad A.
- Khan Muhammad A. S.
- Khan Raja Basit
- Khan Shabuddin
- Khan Shahab
- Khawaja Amir
- Khawaja Zechan
- Khogali Elmoataz
- Kimble Adam
- Kinghorn Alison
- Kirkham Amanda J.
- Knight Benjamin
- Knight Katrina
- Kourkulos Michail
- Krysztopik Richard
- Kumar Pradeep
- Kynaston James
- Kyriakidis Dimitrios
- Lalla Kushik
- Lambert Joel
- Lammy Simon
- Lane Risha
- Larkin David
- Law Jennifer
- Lawther Roger
- Lazim Taha
- Lee Kathryn
- Lee Matthew
- Leeder Paul
- Lennon Hannah
- Lewis Michael
- Lim Henry C. C.
- Lim Pei J.
- Lindsay David
- Lloyd David
- Lo Christina
- Lodhia Joshil
- Longbotham David A.
- Loughlin Paula
- Lovett Bryony
- Luhmann Andreas
- Luther Ali Alison
- Lyons Emma M.
- Macano Christina A. W.
- MacArtney Matthew
- Macdonald Andrew
- Madanipour Suroosh
- Madbak Khaliel
- Madurska Marta
- Magee Conor J.
- Maguire Donal
- Maharaj Geta
- Majeed Ali
- Malcolm Cathy
- Malde Deep
- Malik Nabeela S.
- Mallik Mekhlola
- Mansour Sami
- Manu Mangta
- Manzelli Antonio
- Marriott Paul
- Martin Jack
- Martin Sean T.
- Martin Serena
- Marudanayagam Ravi
- Mason Denise
- Mathur Pawan
- Mawhinney Abi
- Mbuvi James
- McAree Barry
- McCain Stephen
- McCallum Iain J. D.
- McClarey Andrew
- McCune Ken
- McDermott Frank
- McEntee Gerry P.
- McGlone Emma R.
- McGuigan Andrew
- McIlmunn Colin
- McKay Damian
- McKenzie Stephen
- McNair Angus G. K.
- Mealy Ken
- Menzies Donald
- Mercer Stuart J.
- Milburn James
- Mirza Ahmed K.
- Mirza Darius
- Miu Victor
- Mockford Justine Downing Katherine A.
- Mohamed Sarah
- Mohan Helen M.
- Mok Kam Wa Jessica
- Monk David
- Morcous Paul
- Morrison Tamsin E. M.
- Mothe Bhavani Sidhartha
- Mowbray Nicholas
- Mozolowski Kirsty L.
- Mukherjee Dipankar
- Murphy James O.
- Murtaza Ghulam
- Nally Deirdre M.
- Napetti Sara
- Nassar Ahmad H.
- Naumann David
- Nedujchelyn Yuwaraja
- Needham Paul J.
- Newton Katy
- Newton Richard C.
- Ngu Wee Sing
- Nicholson Gary A.
- Nicholson James
- Nicholson James A.
- Nicol Laura
- Nicolay Christopher R.
- Nieto Tom
- Nijjar Rajwinder S.
- Nilsen-Nunn April
- Nilsson Frida
- Noble Fergus
- Nofal Emma
- Noor Nigel
- Nunes Quentin M.
- Obeidallah Mohd Rami
- Ogedegbe Arikoge
- Old Oliver J.
- Orchard Philippa
- Orizu Mavis N.
- O’Dwyer Patrick
- O’Neill Maeve A.
- O’Neill Stephen
- O’Reilly Derek A.
- O’shea Kathryn M.
- O’Sullivan Adrian W.
- Packer Jessica R.
- Padwick Robert
- Pannu Arslan
- Panteleimonitis Sofoklis
- Parappally Ciny P.
- Parmar J.
- Pasquali Sandro
- Patel Abhilasha
- Patel Krashna
- Patel Shakira
- Pati Pradeep
- Pearce Belinda
- Pearson Katherine L.
- Peirce Colin
- Pellen Mike
- Peter Mark B.
- Peterson Mark
- Pezzuto Roberto
- Photi Evangelos
- Phull Manraj
- Pinho-Gomes Ana C.
- Pollock Sarah
- Popplewell Matthew
- Pore Naresh
- Porter Jonathan
- Prasad Abheesh R.
- Prasad Raj
- Preston Shaun R.
- Preziosi Giuseppe
- Prince Sarah
- Psica Alicja
- Puig Sonia
- Puntis Daniel J.
- Puri Yogesh
- Qandeel Haitham
- Rabie Mohamed
- Radwan Rami
- Rae David M.
- Rahman Saquib
- Rajaganeshan Rajasundaram
- Rajendran Ilayaraja
- Ramage Michael I.
- Rao Sudhindra T. V.
- Rate Anthony J.
- Raza Soulat
- Read Edward
- Reddy Marcus
- Reece-Bolton Obuobi
- Reed Joanna
- Reid Alistair
- Rengifo Carla
- Rhys Thomas
- Richards Colin H.
- Riera Manel
- Ritchie Judith
- Robb William
- Roberts Geoffrey P.
- Robinson Sarah
- Robinson Steven J.
- Robinson Stuart
- Rodriguez Dan
- Rodriguez Daniel Urriza
- Roebuck Amanda
- Rogers Paul N.
- Rolph Rachel C.
- Roy Sudipta
- Rutherford Claire L.
- Sadat Mohammed M.
- Sakai Naomi
- Sampat Keerthika
- Samuel Nehemiah
- Sarmah Piyush B.
- Sarvananthan Kas
- Sarveswaran Janahan
- Satheesan Steve
- Saunders Michael
- Sayegh Mazin
- Segaran Ashvina
- Sekhar Hema
- Sen Gourab
- Seymour Keith
- Shabo Wael
- Shah Nayab
- Shah Reena
- Shahin Yousef
- Sheel Andrea R. G.
- Shenoy Hrishikesh
- Shetty Vinutha
- Shier David
- Shingler Guy M.
- Shiwani Muhammad Hanif
- Shrestha Ashish Kiran
- Siddiqi Najaf
- Siddiqui Midhat N.
- Siddiqui Zohaib
- Sillo Toritseju O.
- Silva Michael
- Simpson Duncan J.
- Singh Shailendra
- Singh-Ranger Deepak
- Sinha Sidhartha
- Skelly Brendan L.
- Slavin John P.
- Slawinski Corinna
- Sloane Jake
- Smith Stella R.
- Smith Stella R.
- Sonsale Aniket
- Spearman John
- Spence Gary
- Spreadborough Philip
- Spreadborough Philip
- Starmer Benjamin Z.
- Stevenson Thomas E. J.
- Stewart Duncan J.
- Stirland E.
- Subramanium Dhivya
- Sufi Pratik A.
- Sukha Anisha
- Sutcliffe Robert
- Suttie Stuart
- Sutton Cherith M. L. R.
- Szentpali Karoly
- Tang Cheuk-Bong
- Tanner Nicola
- Tate Sophie
- Tayeh Salim
- Taylor Christopher
- Taylor Greg W.
- Teasdale Rebecca L.
- Templeton Alexa
- Terrace John
- Thakkar Rohan
- Thomas George
- Thompson Ronald L. E.
- Tilston Michael P.
- Toh Simon K. C.
- Tolofari Sotonye
- Tomlinson Mark A.
- Trevatt Alexander E. J.
- Trotter Martin
- Tsang Andrew
- Tsavellas George
- Tuck Liz
- Turner Paul
- Tutton Matthew G.
- Ullah Muhammad Fahad
- Upchurch Emma A.
- Urbonas Tomas
- Varghase Joseph
- Vass David G.
- Vaughan Elizabeth M.
- Vijay Vardhini
- Vijayan Deepak
- Vijayanand Dhakshinamoorthy
- Villatoro Eduardo
- Virupaksha Suvi
- Vitone Louis J.
- Vohra Ravinder S.
- Wadley Martin
- Wainwright Denise
- Wajed Saj
- Wallace Tom
- Wardle Stacy
- Warren Conor
- Watkin Helen
- Watson Angus J. M.
- Watson Nicholas F.
- Wayman John
- Weaver Simon
- Weber Beatrix
- Weber Beatrix
- Weerasinghe Chamindri
- Welbourn Hannah
- Wheatley Kevin
- White Timothy J.
- Wijetunga Imeshi
- Wild Jonathan R. L.
- Wilkinson Marc D.
- Williams Sophie V.
- Williamson Tracey K.
- Willson Peter D.
- Wilson Michael S. J.
- Wilson Timothy R.
- Winter Des C.
- Winter Hannah
- Wood Christopher P. J.
- Wood Peter
- Wood Simon
- Woodman Thomas
- Yahya Salama
- Yao Caroline
- Yeldham Geoffrey
- Yoganathan Thusidaran
- Youssef Haney
- Zafar Sara
- Zafrani Zakhi
- Zarsadias Prizzi
- Zeeshan Saquib
- Zhang Catherine
- Ziprin Paul
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
Background: The ability to accurately predict operative duration has the potential to optimise theatre efficiency and utilisation, thus reducing costs and increasing staff and patient satisfaction. With laparoscopic cholecystectomy being one of the most commonly performed procedures worldwide, a tool to predict operative duration could be extremely beneficial to healthcare organisations.
Methods: Data collected from the CholeS study on patients undergoing cholecystectomy in UK and Irish hospitals between 04/2014 and 05/2014 were used to study operative duration. A multivariable binary logistic regression model was produced in order to identify significant independent predictors of long (> 90 min) operations. The resulting model was converted to a risk score, which was subsequently validated on second cohort of patients using ROC curves.
Results: After exclusions, data were available for 7227 patients in the derivation (CholeS) cohort. The median operative duration was 60 min (interquartile range 45–85), with 17.7% of operations lasting longer than 90 min. Ten factors were found to be significant independent predictors of operative durations > 90 min, including ASA, age, previous surgical admissions, BMI, gallbladder wall thickness and CBD diameter. A risk score was then produced from these factors, and applied to a cohort of 2405 patients from a tertiary centre for external validation. This returned an area under the ROC curve of 0.708 (SE = 0.013, p 90 min increasing more than eightfold from 5.1 to 41.8% in the extremes of the score.
Conclusion: The scoring tool produced in this study was found to be significantly predictive of long operative durations on validation in an external cohort. As such, the tool may have the potential to enable organisations to better organise theatre lists and deliver greater efficiencies in care
Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial
- Author
- Abano Nenette
- Abbdul-saheb Mudhar
- Adedoyin Temi
- Adell Victoria
- Adesina Tolu
- Adie Katja
- Adil-Smith Jennifer
- Ahmad Nasar
- Ahmed Ashraf
- Ahmed Iman
- Al-Mayhani Talal
- Al-Shahi Salman Rustam
- Alam Mohammad Irfan
- Albazzaz Mo
- Ali Ali
- Alipio Francis
- Allen Christopher
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- Stafford Samantha
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- Wallace Rebecca
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- Walters Ashleigh
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- Wardlaw JM
- Watchurst Caroline
- Waterfield Kelly
- Waterfield Kelly
- Watson Fran
- Waugh Dean
- Webb Tom
- Webber Adam
- Webster Timothy
- Weinling Marie
- Weir Nic
- Weir Pauline
- Welch Angela
- Werring DJ
- Whitcher Alison
- White James
- White Julie
- White PM
- White Susan
- Whiteley WN
- Whiteman Jessica
- Whiteman Jessica
- Whiting Robert
- Whittamore Katherine
- Wiggam Ivan
- Wilding Peter
- Wilkes Gwendoline
- Wilkinson Mark
- Willberry Angela
- Williams Carol
- Williams Rebecca
- Williams-Yesson Barbara
- Willmot Mark
- Wilson David
- Wilson Duncan
- Wilson Jenny
- Wilson Lisa
- Wilson Sarah
- Wiltshire Alison
- Wood Diane
- Wood Edith
- Wood Lisa
- Woodward Stephen
- Wright Fiona
- Wroath Belinda
- Wynter Inez
- Yadava Rajendra
- Yip Brigitte
- Young Andrew
- Zachariah George
- Zahoor Tajammal
- Zoe Mellor
- Publication venue
- 'Elsevier BV'
- Publication date
- 29/06/2019
- Field of study
Background:
Antiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial haemorrhage. Patients surviving the commonest subtype of intracranial haemorrhage, intracerebral haemorrhage, are at risk of both haemorrhagic and occlusive vascular events, but whether antiplatelet therapy can be used safely is unclear. We aimed to estimate the relative and absolute effects of antiplatelet therapy on recurrent intracerebral haemorrhage and whether this risk might exceed any reduction of occlusive vascular events.
Methods:
The REstart or STop Antithrombotics Randomised Trial (RESTART) was a prospective, randomised, open-label, blinded endpoint, parallel-group trial at 122 hospitals in the UK. We recruited adults (≥18 years) who were taking antithrombotic (antiplatelet or anticoagulant) therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage, discontinued antithrombotic therapy, and survived for 24 h. Computerised randomisation incorporating minimisation allocated participants (1:1) to start or avoid antiplatelet therapy. We followed participants for the primary outcome (recurrent symptomatic intracerebral haemorrhage) for up to 5 years. We analysed data from all randomised participants using Cox proportional hazards regression, adjusted for minimisation covariates. This trial is registered with ISRCTN (number ISRCTN71907627).
Findings:
Between May 22, 2013, and May 31, 2018, 537 participants were recruited a median of 76 days (IQR 29–146) after intracerebral haemorrhage onset: 268 were assigned to start and 269 (one withdrew) to avoid antiplatelet therapy. Participants were followed for a median of 2·0 years (IQR [1·0– 3·0]; completeness 99·3%). 12 (4%) of 268 participants allocated to antiplatelet therapy had recurrence of intracerebral haemorrhage compared with 23 (9%) of 268 participants allocated to avoid antiplatelet therapy (adjusted hazard ratio 0·51 [95% CI 0·25–1·03]; p=0·060). 18 (7%) participants allocated to antiplatelet therapy experienced major haemorrhagic events compared with 25 (9%) participants allocated to avoid antiplatelet therapy (0·71 [0·39–1·30]; p=0·27), and 39 [15%] participants allocated to antiplatelet therapy had major occlusive vascular events compared with 38 [14%] allocated to avoid antiplatelet therapy (1·02 [0·65–1·60]; p=0·92).
Interpretation:
These results exclude all but a very modest increase in the risk of recurrent intracerebral haemorrhage with antiplatelet therapy for patients on antithrombotic therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage. The risk of recurrent intracerebral haemorrhage is probably too small to exceed the established benefits of antiplatelet therapy for secondary prevention
Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial
- Author
- Abano Nenette
- Abbdul-saheb Mudhar
- Adedoyin Temi
- Adell Victoria
- Adesina Tolu
- Adie Katja
- Adil-Smith Jennifer
- Ahmad Nasar
- Ahmed Ashraf
- Ahmed Iman
- Al-Mayhani Talal
- Al-Shahi Salman Rustam
- Alam Mohammad Irfan
- Albazzaz Mo
- Ali Ali
- Alipio Francis
- Allen Christopher
- Allison Joanna
- Amey Isobel
- Amis Elaine
- Amlani Sageet
- Amoils Shannon
- Amor Kelly
- Anderson Rosemary
- Andole Sreeman
- Anjum Talat
- Ankolekar Sandeep
- Annamalai Arunkumar
- Anthony Alpha
- Anversha Ajmal
- Anwar Ijaz
- Anwar Sajjad
- Appleton Jason
- Argandona Lucia
- Armitage Jane
- Ashton Amy
- Atkinson Natalie
- Auld Grace
- Avis Joanne
- Aweid Basaam
- Ayres Georgina
- Azhar Khalid
- Bagnall Caroline
- Baig Farrukh
- Baigent Colin
- Bailey Duncan
- Baird Yolanda
- Bakawala Rehana
- Baker John
- Baker Pauline
- Balazikova Olga
- Balian Linda
- Baliga Vidya
- Balitska Olesia
- Ball Julie
- Ball Margaret
- Ballantine Robert
- Bamford John
- Banaras Azra
- Barber Mark
- Barbon Emma
- Barker James
- Barr Charlotte
- Barrie Elizabeth
- Barron Luke
- Barry Adrian
- Bateman Gavin
- Bates Michelle
- Bathula Rajaram
- Battersby-Wood Emma
- Bayliss Pauline
- Beadle Hannah
- Bearne Helen
- Beaty Teresa
- Beaves Emily
- Bell Angela
- Bell Jo
- Bell Murdina
- Bellfield Ruth
- Beranova Eva
- Bergin Adrian
- Bhakri Harbens
- Bhalla Ajay
- Bharaj Kiranjit
- Bhargava Maneesh
- Bhaskaran Biju
- Bhatnagar Priya
- Birchall Kathryn
- Birns Jonathan
- Black Toby
- Blades Alex
- Blair Caroline
- Blair Caroline
- Blair Gordon
- Blane Sujata
- Blank Catrin
- Blight Adrian
- Board Joanne
- Board Sarah
- Bokhari Maria
- Bond Kirsty
- Bowring Angela
- Boxall Cherish
- Breeds Joanna
- Brew Helen
- Brezitski Maria
- Bridger Hayley
- Brodie Fiona
- Brotherton Lucy
- Broughton David
- Brown Claire
- Brown Ellen
- Brown Pauline
- Brown Sarah
- Bruce David
- Buchanan David
- Buck Amanda
- Buckle Steve
- Buckle Steve
- Buckley Clare
- Bunea George
- Burger Ilse
- Burgess Laura
- Burgess Seona
- Burssens Evelyne
- Butler Adrian
- Butler Donna
- Butler Rebecca
- Butterworth-Cowin Nicola
- Button Denise
- Buxton Jean
- Byrne Anthony
- Cageao Julie
- Caine Sarah
- Campbell Robert
- Carpenter Michael
- Carpio Racquel
- Carrie Johanna
- Cassidy Tim
- Causley Chelsea
- Chadbourn Indra
- Chadha Dinesh
- Chamberlain Angela
- Chan Kelly
- Chandrakumar Aberami
- Chapman Kath
- Chapman Nicola
- Charles Bethan
- Chatterjee Kausic
- Chaudhry Afnan
- Chauhan Meena
- Chenna Srikanth
- Cherian Suja
- Cheripelli Bharath Kumar
- Chopra Neha
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- Srinivasan Meena
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- Stafford Samantha
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- Walters Ashleigh
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- Wardlaw JM
- Watchurst Caroline
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- Waterfield Kelly
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- Waugh Dean
- Webb Tom
- Webber Adam
- Webster Timothy
- Weinling Marie
- Weir Nic
- Weir Pauline
- Welch Angela
- Werring DJ
- Whitcher Alison
- White James
- White Julie
- White PM
- White Susan
- Whiteley WN
- Whiteman Jessica
- Whiteman Jessica
- Whiting Robert
- Whittamore Katherine
- Wiggam Ivan
- Wilding Peter
- Wilkes Gwendoline
- Wilkinson Mark
- Willberry Angela
- Williams Carol
- Williams Rebecca
- Williams-Yesson Barbara
- Willmot Mark
- Wilson David
- Wilson Duncan
- Wilson Jenny
- Wilson Lisa
- Wilson Sarah
- Wiltshire Alison
- Wood Diane
- Wood Edith
- Wood Lisa
- Woodward Stephen
- Wright Fiona
- Wroath Belinda
- Wynter Inez
- Yadava Rajendra
- Yip Brigitte
- Young Andrew
- Zachariah George
- Zahoor Tajammal
- Zoe Mellor
- Publication venue
- 'Elsevier BV'
- Publication date
- 29/06/2019
- Field of study
Background:
Antiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial haemorrhage. Patients surviving the commonest subtype of intracranial haemorrhage, intracerebral haemorrhage, are at risk of both haemorrhagic and occlusive vascular events, but whether antiplatelet therapy can be used safely is unclear. We aimed to estimate the relative and absolute effects of antiplatelet therapy on recurrent intracerebral haemorrhage and whether this risk might exceed any reduction of occlusive vascular events.
Methods:
The REstart or STop Antithrombotics Randomised Trial (RESTART) was a prospective, randomised, open-label, blinded endpoint, parallel-group trial at 122 hospitals in the UK. We recruited adults (≥18 years) who were taking antithrombotic (antiplatelet or anticoagulant) therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage, discontinued antithrombotic therapy, and survived for 24 h. Computerised randomisation incorporating minimisation allocated participants (1:1) to start or avoid antiplatelet therapy. We followed participants for the primary outcome (recurrent symptomatic intracerebral haemorrhage) for up to 5 years. We analysed data from all randomised participants using Cox proportional hazards regression, adjusted for minimisation covariates. This trial is registered with ISRCTN (number ISRCTN71907627).
Findings:
Between May 22, 2013, and May 31, 2018, 537 participants were recruited a median of 76 days (IQR 29–146) after intracerebral haemorrhage onset: 268 were assigned to start and 269 (one withdrew) to avoid antiplatelet therapy. Participants were followed for a median of 2·0 years (IQR [1·0– 3·0]; completeness 99·3%). 12 (4%) of 268 participants allocated to antiplatelet therapy had recurrence of intracerebral haemorrhage compared with 23 (9%) of 268 participants allocated to avoid antiplatelet therapy (adjusted hazard ratio 0·51 [95% CI 0·25–1·03]; p=0·060). 18 (7%) participants allocated to antiplatelet therapy experienced major haemorrhagic events compared with 25 (9%) participants allocated to avoid antiplatelet therapy (0·71 [0·39–1·30]; p=0·27), and 39 [15%] participants allocated to antiplatelet therapy had major occlusive vascular events compared with 38 [14%] allocated to avoid antiplatelet therapy (1·02 [0·65–1·60]; p=0·92).
Interpretation:
These results exclude all but a very modest increase in the risk of recurrent intracerebral haemorrhage with antiplatelet therapy for patients on antithrombotic therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage. The risk of recurrent intracerebral haemorrhage is probably too small to exceed the established benefits of antiplatelet therapy for secondary prevention
New genetic loci link adipose and insulin biology to body fat distribution.
- Author
- Aalto Ville
- Aasarød Knut
- Abecasis Goncalo R
- Abecasis Gonçalo
- Absher Devin
- Adair Linda S
- Adam Martin
- Adeyemo Adebowale
- Ahlqvist Emma
- Ahmadi Kourosh R
- Ahola Aila
- Ainali Chrysanthi
- Akylbekova Ermeg
- Ala-Korpela Mika
- Alavere Helen
- Albagha Omar M E
- Albrecht Eva
- Alen Markku
- Alexander Myriam
- Alhenc-Gelas François
- Alizadeh Behrooz Z
- Allison Matthew A
- Alonso Nerea
- Altshuler David
- Ambite Jose Luis
- Amin Najaf
- Amouyel Philippe
- An Ping
- Anderson Carl A
- Anderson Denise
- Anderson Garnet
- Andrews Jeanette S
- Antonella Mulas
- Antti Jula
- Aragaki Aaron K
- Arking Dan E
- Arnold Alice
- Arnold Alice M
- Arora Pankaj
- Arscott Gillian M
- Artigas Maria Soler
- Arveiler Dominique
- Asiki Gershim
- Aspelund Thor
- Assimes Themistocles L
- Atalay Mustafa
- Atkinson Elizabeth J
- Aulchenko Yurii
- Avery Christy
- Bain Stephen C
- Bakker Stephan J L
- Balcells Susana
- Balkau Beverley
- Ballantyne Christie M
- Balmforth Anthony J
- Bandinelli Stefania
- Barbalic Maja
- Barrett Amy
- Barroso Ines
- Barroso Inês
- Basart Hanneke
- Basart Hanneke V
- Bataille Veronique
- Baumert Jens
- Beckmann Jacques S
- Beekman Marian
- Been Latonya F
- Beilby John
- Beilby John P
- Bell Jordana T
- Bellis Claire
- Bennett Amanda J
- Bennett Franklyn
- Berenson Gerald S
- Bergman Richard N
- Bergmann Sven
- Berndt Sonja I
- Berne Christian
- Bidulescu Aurelian
- Bielak Lawrence F
- Bierut Laura J
- Biffar Reiner
- Bis Joshua C
- Blackburn Hannah
- Blangero John
- Blankenberg Stefan S
- Blüher Matthias
- Boban Mladen
- Bochud Murielle
- Boehm Bernhard O
- Boehnke Michael
- Boerwinkle Eric
- Boezen H Marike
- Bolton Jennifer L
- Bolton Judith A Hoffman
- Bonnet Fabrice
- Bonnycastle Lori L
- Boomsma Dorret I
- Borecki Ingrid
- Boright Andrew P
- Borja Judith B
- Bornstein Stefan R
- Boston Jonathan
- Bots Michiel L
- Bouatia-Naji Nabila
- Bouchard Claude
- Bovet Pascal
- Boyd Heather A
- Bragg-Gresham Jennifer L
- Brambilla Paolo
- Brand Eva
- Brand Stefan-Martin
- Brandi Maria Luisa
- Braund Peter S
- Brennan Eoin P
- Brismar Kerstin
- Brody Jennifer
- Broekmans Frank J
- Broer Linda
- Brown Matthew A
- Brown Morris J
- Brown-Gentry Kristin
- Bruinenberg Marcel
- Buchkovich Martin L
- Buckley Brendan M
- Buil Alfonso
- Bull Shelley B
- Burgdorf Christof
- Buring Julie E
- Burnett Mary S
- Burnier Michel
- Burri Andrea
- Burton Paul R
- Bush William S
- Busonero Fabio
- Buxbaum Sarah G
- Buyske Steve
- Buzkova Petra
- Byrne Enda M
- Böger Carsten A
- Böhringer Stefan
- Böttcher Yvonne
- Cambien Francois
- Campbell Harry
- Campbell Susan
- Carba Delia B
- Carlson Chris
- Carlson Olga D
- Carty Cara
- Casas Juan P
- Caspersen Ida H
- Castano-Betancourt Martha
- Cauchi Stéphane
- Cauley Jane A
- Caulfield Mark
- Cavalieri Margherita
- Cazier Jean-Baptiste
- Center Jacqueline R
- Cesana Giancarlo
- Chakravarti Aravinda
- Chambers John
- Chandak Giriraj R
- Chang Hsing-Yi
- Chang Yen-Pei C
- Chanock Stephen J
- Charchar Fadi J
- Chasman Dan
- Chaturvedi Nish
- Chen Constance
- Chen Han
- Chen Ida
- Chen Jin
- Chen Ming-Huei
- Chen Wei
- Chen Yii-Der Ida
- Cheng Iona
- Cheng Sulin
- Chines Peter S
- Cho Yoon Shin
- Choi Murim
- Chouraki Vincent
- Christiansen Claus
- Chu Audrey Y
- Cimponeriu Dan
- Ciullo Marina
- Clark Graeme R
- Clarke Robert
- Claudi-Boehm Simone
- Coassin Stefan
- Cochran Barbara
- Cole Shelley
- Colhoun Helen
- Colhoun Helen M
- Collins Francis S
- Collins Rory
- Connell John M
- Cooper Cyrus
- Cooper Jackie A
- Cooper Matthew N
- Cooper Richard S
- Coresh Josef
- Cornelis Marilyn C
- Corre Tanguy
- Corsi Anna Maria
- Couper David
- Cousminer Diana L
- Coviello Andrea D
- Cox David
- Crawford Dana
- Crisponi Laura
- Croteau-Chonka Damien C
- Cucca Francesco
- Cummings Steven R
- Cupples Adrienne L
- Cupples L Adrienne
- Curhan Gary
- d'Adamo Pio
- Dahgam Santosh
- Dailiana Zoe
- Danesh John
- Danoy Patrick
- Dastani Zari
- Davies Gail
- Daw E Warwick
- Day Felix R
- Day Ian N M
- de Andrade Mariza
- de Boer Ian H
- de Boer Rudolf A
- de Faire Ulf
- de Geus Eco J C
- Deary Ian J
- Dedoussis George
- Dedoussis George V
- Dedoussis George V Z
- Deelen Joris
- Deelman Ewa
- Dehghan Abbas
- Delgado Graciela
- Deloukas Panagiotis
- Deloukas Panos
- Demerath Ellen W
- Demirkan Ayse
- Demirkan Ayşe
- Den Hertog Heleen M
- Denniff Matthew
- Dennison Elaine M
- Dermitzakis Emmanouil T
- Deshmukh Harshal
- Deshmukh Harshal A
- Devuyst Olivier
- di Meglio Paola
- Diemert Patrick
- Dimas Antigone S
- Dimitriou Maria
- Ding Jingzhong
- Do Ron
- Dominiczak Anna F
- Doney Alex
- Dong Yanbin
- Donnelly Louise A
- Doumatey Ayo
- Dreisbach Albert W
- Drong Alexander W
- Duggan David
- Dumitrescu Logan
- Duncan Bruce B
- Duncan Emma L
- Dupuis Josee
- Dupuis Josée
- Durbin Richard
- Durda Peter
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- van der Harst Pim
- van der Klauw Melanie M
- van der Schoot C Ellen
- van der Schouw Yvonne T
- van Duijn Cornelia
- Van Duijn Cornelia
- van Gils Carla H
- van Gilst Wiek H
- van Heemst Diana
- Van Hul Wim
- van Meurs Joyce B J
- van Meurs Joyve B J
- van Nierop Peter
- van Oort Floor V A
- van Pelt L Joost
- van Schoor Natasja M
- Van Vliet-Ostaptchouk Jana V
- van Wingerden Sophie
- van Wingerden Sophie W
- Van Zuydam Natalie
- Vandenput Liesbeth
- Varga Tibor V
- Vartiainen Erkki
- Vasan Ramachandran S
- Vedantam Sailaja
- Veldre Gudrun
- Verlaan Dominique
- Vernon Smith Albert
- Veronesi Giovanni
- Verweij Niek
- Verwoert Germaine
- Verwoert Germaine C
- Viigimaa Margus
- Viikari Jorma
- Vinay D G
- Vineis Paolo
- Vink Jacqueline M
- Virtamo Jarmo
- Visscher Peter M
- Visser Jenny A
- Vitart Veronique
- Vohl Marie-Claude
- Voight Benjamin F
- Volcik Kelly A
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- Vonk Judith M
- Voorhuis Marlies
- Völker Uwe
- Völzke Henry
- Wadén Johan
- Waeber Gerard
- Waeber Gérard
- Wagenknecht Lynne E
- Waggott Daryl
- Wagner Peter J
- Wain Louise V
- Wainwright Nicholas
- Waite Lindsay L
- Walker Mark
- Wallace Leanne
- Wallaschofski Henri
- Wallentin Lars
- Wang Hansong
- Wang Jie Jin
- Wang Thomas J
- Wang Xiaoling
- Wareham Nicholas
- Wareham Nick J
- Warrington Nicole M
- Watanabe Richard M
- Waterworth Dawn
- Watkins Hugh
- Weder Alan B
- Weedon Michael N
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- Wells George A
- Wennauer Roman
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- Wheeler Eleanor
- Wheeler Heather E
- Whincup Peter H
- Whitfield John B
- Wichmann H Erich
- Wichmann H-Erich
- Widen Elisabeth
- Wiggins Kerri L
- Wijmenga Cisca
- Wijnands-van Gent Colette J M
- Wild Philipp S
- Wild Sarah H
- Wilk Alicja
- Wilkens Lynne
- Willems Sara M
- Willemsen Gonneke
- Willemsvan-vanDijk Ko
- Willenborg Christina
- Willer Cristen J
- Williams Frances M K
- Williams Rasheeda
- Williams Winfred W
- Willner Dana
- Wilsgaard Tom
- Wilson James F
- Wilson James G
- Wilson Sarah
- Wilson Scott G
- Winkler Thomas
- Witteman Jacqueline C
- Witteman Jacqueline C M
- Wojczynski Mary K
- Wolffenbuttel Bruce H R
- Wong Andrew
- Wong Tien Y
- Woo Jean
- Wood Andrew R
- Wood Andy
- Workalemahu Tsegaselassie
- Wright Alan F
- Wu Chunyuan
- Wu Joseph M W
- Wu Ying
- Würtz Peter
- Xiao Su-Mei
- Yajnik Chittaranjan S
- Yang Jian
- Yang Qiong
- Yang Tsun-Po
- Yao Jie
- Yengo Loïc
- Yerges-Armstrong Laura M
- Young Alicia
- Young Elizabeth H
- Young J H
- Young Lauren
- Yuan Xin
- Zaboli Ghazal
- Zalloua Pierre A
- Zarrabeitia María T
- Zelenika Diana
- Zemunik Tatijana
- Zerbini Gianpaolo
- Zgaga Lina
- Zhai Guangju
- Zhang Feng
- Zhang Qunyuan
- Zhang Weihua
- Zhao Jing Hua
- Zhao Wei
- Zheng Hou-Feng
- Zheng Wei
- Zhou Yanhua
- Zhu Haidong
- Zhu Kun
- Zhu Xiaofeng
- Zhuang Wei V
- Zhuang Wei Vivian
- Ziegler Andreas
- Zillikens M Carola
- Zimmermann Martina E
- Zitting Paavo
- Zondervan Krina T
- Zukowska-Szczechowska Ewa
- Zygmunt Marek
- Ärnlöv Johan
- Österholm Anne-May
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
- Adam Catherine
- Adams Charles Q.
- Adamson Aaron
- Adekoya Emmanuel
- Adio-Oduola Babajide
- Aerts Andrea
- Aggarwal Arun
- Ahmadi Alireza
- Ahmed Shahana
- Aimable Matthew
- Ainscough Rachael
- Ait-Zahra Mostafa
- Aizu Tomoyuki
- Alcivare Dana
- Alegria Michelle
- Ali Alla
- Ali Johar
- Allegria-hartmann Michelle
- Alleman Jennifer
- Allen Carlana C.
- Allen Heather
- Allen Nicole R.
- Allen Susan
- Allen Thaddeus
- Almeida Jeff
- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
- Ambrose Karen
- Ambrose Kerrie
- Amemiya Chris
- Amico-Keller Gina
- Amin Amita G.
- Anderson Mechele
- Anderson Scott
- Anderson Scott
- Andora Janice
- Andredesz Carol
- Andrew Robert
- Andrews Dan
- Andrews Daniel
- Andrews Neil
- Andrews Stephanie
- Andriese Tim
- Anthouard Véronique
- Antonarakis Stylianos E.
- Anyalebechi Vivian
- Aoki Norie
- Apostolou Sinoula
- Apweiler Eva
- Arachchi Harindra
- Arai Rie
- Arbery Hazel
- Arcaina Marlon
- Arcaina Terisita
- Archer Beth
- Arellano Andre
- Arellano-Jones Perry
- Armbruster Jeff
- Armstrong Jon
- Arredondo Dilrukshi P.
- Arredondo Heather Hope
- Artiguenave François
- Asakawa Shuichi
- Asakawa Teruyo
- Ash Gareth
- Ashcroft Kevin
- Ashurst Jennifer
- Ashwell Robert
- Ashworth Linda K.
- Aslanidis Cara
- Asomugha Chinwe O.
- Asuncion Lawreen
- Atkin Deborah
- Atkinson Andrea
- Atkinson Barry
- Attix Cristina
- Attwood John
- Aubin Keith
- Auger Katherine
- Austin Shannon Michelle
- Avila Aaron
- Avis Terry
- Ayele Mulu
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- Babbage Sarah
- Bach Phil
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- Bacon Joanne
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- Baertsch Robert
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- Bailey Jonathan
- Bajorek Eva
- Baker Andrew
- Baker Dan
- Baker M.
- Baker Richard
- Bakis Michele
- Baldwin Jennifer
- Banda Michael
- Banerjee Ruby
- Bao Jingyue
- Bao Qiyu
- Bao Weidong
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- Barbaria Joseph A.
- Barbe Valérie
- Bardill Simon
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- Barker Darren
- Barker Gary
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- Bartlett Rebecca
- Basham Victoria
- Bashman David
- Basu Suba
- Bateman Alex
- Bates Karen
- Battles John
- Batzer Mark
- Baumgart Cornelia
- Baumohl Jason
- Baynes Caroline
- Bayul Tashi
- Beall Keith
- Beard Lisa
- Beard Susan
- Beare David
- Beasley Alastair
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- Bituin Aleksandr
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- Blair Jessica Anne
- Blakey Sarah
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- Holtz Ann
- Holtzer Caleb
- Homsi Deana K.
- Homsi Farah J.
- Honan Tracy
- Hood Leroy
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- Huang Wei
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- Hyde David
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- Idlebird Devincent G.
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- Imo Kelvin C.
- Inacio Nicole
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- Ishibashi Akiko
- Ishikawa Sabine K.
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- Jaeger Sara
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- Kettleborough Ross
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- Lowenstein Michael G.
- Lowry Stephen
- Lozado Ryan J.
- Lu Lingfeng
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- Ludeman Thom
- Lui Annie
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- MacLean Christine
- Madabhushi Ramki
- Madu Renita C.
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- McMurray Kimberly L.
- McNinch Jenny
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- Meidi Patrick
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- Nakato Eriko
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- Nandkeshwar Richard
- Nankervis Colin E.
- Naranjo Cleo M.
- Nash William
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- Nazareth Lynne V.
- Neal Dearl D.
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- Nwokenkwo Stanley
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- O\u27Donovan Daniel
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- Okumura Reina
- Okwuonu Geoffrey O.
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- Olarnpunsagoon Alisa
- Olivas Jason
- Oliver Hayley
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- Olson Maynard V.
- Omotosho Bamidele
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- Ow David
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- Patel Dina
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- Patel Ritesh
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- Paul Shelia
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- Pennacchio Len A.
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- Percy Chantel
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- Perez Lesette M.
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- Pourrajabi Nima M.
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- Ridler Kerry
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- Sasaki Takashi
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- Saurin William
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- Saxman Eric
- Scarpelli Claude
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- Scherer Steven Edward
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- Sonnhammer Erik
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- Stege Justin T.
- Steingruber Helen
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- Stetson Kevin
- Stevko Victor
- Steward Charles
- Stewart Aengus
- Stewart Michael
- Still Ian
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- Stone Evan
- Stone Sabrina
- Stoppard Lisa
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- Storey Roy
- Stowe Sarah
- Strachan Carol
- Strachan Greg
- Strasser Jonathan
- Stribling Claire
- Strong Cynthia
- Stubbs Lisa
- Stubbs Matthew
- Stultz Janet
- Sturdy John
- Su Xiaohu
- Subramanian Sandhya
- Subramanian Sandhya
- Sudbrak Ralf
- Sugnet Charles W.
- Sulston John
- Summers Leslie J.
- Sun Hui
- Sun Jiajia
- Sun Jiandong
- Sun Jiu Qin
- Sun Min
- Sun Tao
- Sun Wei
- Sun Yongqiao
- Sun Yu
- Sun Yue
- Sutherland Grant R.
- Sutherland Robert D.
- Sutton Angelica E.
- Svatek Amanda F.
- Svetz Jessica
- Svetz Leah Anne
- Swainson Chris
- Swann Mark
- Swarbreck David
- Swearengen-Shahid Sharhonda
- Sycamore Neil
- Ségurens Béatrice
- Tabor Paul E.
- Tacey Kristina
- Tagett Beckie
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- Takaoka Tori
- Takayanagi Atsushi
- Takenaka Tracy
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- Tam Serena
- Tamerisa Kavitha S.
- Tamirisa Aparna
- Tan Olivia
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- Tan Xinyu
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- Tansey Jennifer
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- Taring Elizabeth
- Tatsuyama Miho
- Tatum Owatha I.
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- Telford Ethan Brett
- Tenzin Pema
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- Tesfaye Senait
- Tesmer Judith G.
- Tester Julieanne
- Thayer Nina
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- Theil James
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- Thexton David
- Thies Stephanie
- Thomas Craig
- Thomas Daniel
- Thomas Daryl J.
- Thomas Karen
- Thomas Nicole
- Thomas Paulette
- Thomas Ruth
- Thomas Shereen
- Thommai Roselin
- Thompson Linda S.
- Thorne Rachel Diane
- Thorpe Andrea
- Thorpe Karen
- Thoulutsang Yama
- Threadgold Glen
- Thurston Scott
- Tian Chaoguang
- Tian Chaoguang
- Tian Wei
- Tian Yan
- Tian Yong
- Tian Yuqing
- Tice Hope
- Tighe Damon
- Tin-Wollam Aye M.
- Tinsley Emma
- Tochigi Miwako
- Togashi Naoko
- Tomizawa Iori
- Tomlinson Chad
- Tong Jingli
- Topham Kerri
- Torcaso Bill
- Torney David C.
- Totoki Yasushi
- Towey Sarah
- Toyoda Atsushi
- Tracey Alan
- Tran Ly Thanh
- Tran-Gyamfi Mary
- Trani Lee
- Trankiem Margie
- Trask Barbara J.
- Travers Johnathan
- Trejos Zulma Y.
- Treuhaft Marianne
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- Tromans Anthony
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- Un Chun
- Ung Quyen
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- Wong Gane K-S
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- Wright Kristin
- Wright Rita A.
- Wu Chungen
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- Xue Rui
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- Yadav Shailendra
- Yakub Syed
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- Yamamoto Yuko
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- Yang Hao
- Yang Huanming
- Yang Huanming
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- Yang Shiaw-Pyng
- Yang Shudong
- Yang Xiaonan
- Yang Xiaonan
- Yang Xiaoping
- Yang Yongkui
- Yano Candance
- Yao Zhijian
- Yao Zhijian
- Yaspo Marie-Laure
- Ye Chen
- Yeager Shane
- Yeh Mimi
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- Yeshitela Rahel Retta
- Yoakum Martin
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- Zainoun Joanne
- Zembeck Lisa
- Zeng Yixin
- Zhai Dong
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- Zhang Bo
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- Zhang Guohua
- Zhang Haiqing
- Zhang Haiqing
- Zhang Haiqing
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- Zhang Hongbo
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- Zhang Jingjing
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- Zhang Jiuchun
- Zhang Jiuchun
- Zhang Lanzhi
- Zhang Li
- Zhang Li
- Zhang Meihua
- Zhang Meng
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- Zhang Ruhua
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- Zhang Xianglin
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- Zhang Xiuqing
- Zhang Yan
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- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Evidence synthesis to inform model-based cost-effectiveness evaluations of diagnostic tests: a methodological systematic review of health technology assessments
- Author
- Adele Francis
- Adina Najwa Kamarudin
- Aeliko Zwinderman
- Aileen Clarke
- Aileen Clarke
- Alastair Gale
- Albert S. Yeung
- Alex Carter
- Alexander W. Levis
- Alexandra Enocson
- Alfonso Muriel
- Alice Sitch
- Alice Sitch
- Alice Sitch
- Alison Holmes
- Alison Smith
- Alison Smith
- Andrea Benedetti
- Andrea Horvath
- Andrew Beggs
- Andrew Hattersley
- Andrew Hattersley
- Andrew Lewington
- Andrew Mumford
- Andrew Plumb
- Andrew StJohn
- Andy Dickens
- Angel Candela-Toha
- Angus Jones
- Angus Jones
- Ann van den Bruel
- Anna Noel-Storr
- Anne Rummer
- Anne Rutjes
- Annika Hoyer
- Antoinette de Jong
- Antonia Zapf
- Augusto Azuara-Blanco
- Aïssatou Paye
- Barnaby Reeves
- Bavo De Cock
- Beatriz Tucker
- Ben Van Calster
- Ben Van Calster
- Ben Van Calster
- Bernard G. Francq
- Bernard G. Francq
- Bernd Löwe
- Bethany Shinkins
- Bethany Shinkins
- Beverley Shields
- Beverley Shields
- Bogdan Grigore
- Brett D. Thombs
- Brian Nicholson
- Brian Willis
- Brian Willis
- Brooke Levis
- Byron Wallace
- Camille M. Lassale
- Carl Moons
- Carla Deakin
- Cathie Sturgeon
- Charles Boachie
- Charles Boachie
- Charles H. Bombardier
- Chris Cooper
- Chris Farmer
- Chris Hyde
- Chris Hyde
- Chris Hyde
- Chris Hyde
- Chris Hyde
- Chris Hyde
- Chris Rogers
- Chris Stinton
- Christa Cobbaert
- Christiana Naaktgeboren
- Christiana Naaktgeboren
- Christiana Naaktgeboren
- Christoph Ebert
- Claire Smith
- Clare Davenport
- Clare Davenport
- Clare Davenport
- Coreline Burggraaff
- Corran Roberts
- Craig Ramsay
- Cécile Proust-Lima
- Daan Nieboer
- Daniel Lasserson
- David Cairns
- David Fitzmaurice
- David Lorente Estelles
- David McCartney
- Dean McMillan
- Denniis Petrie
- Dirk Timmerman
- Dirk Timmerman
- Doug Altman
- Doug Altman
- Doug Altman
- Doug Altman
- Doug G. Altman
- Douglas Altman
- Douglas G. Altman
- Douglas G. Altman
- Douglas G. Altman
- Dwenda Gjerdingen
- E. C. Martin
- Eivind Antonsen Segtnan
- Elizabeth M. Hensor
- Elizabeth Mitchell
- Emilie Bessede
- Emma Hall
- Emma Helbren
- Emmanuel Ogundimu
- Emmanuelle Kempf
- Ewan Pearson
- Ewan Pearson
- Ewoud Schuit
- Ewout W. Steyerberg
- Farah Seedat
- Femke Lamers
- Flavia de Lima Osório
- Frances Nixon
- Fueloep Scheibler
- G. Bruce Mann
- Gail Hayward
- Gaj Vidmar
- Gary Collins
- Gary Collins
- Gary Collins
- Gary Collins
- Gary Collins
- Gary Collins
- Gary S. Collins
- Gary S. Collins
- Gary S. Collins
- Gary S. Collins
- Gauraang Batnagar
- Gavin J. Murphy
- George C. M. Siontis
- George Hanna
- George Hanna
- George Hanna
- Gerta Rücker
- Gianni D. Angelini
- Gowri Gopalakrishna
- Gowri GopalaKrishna
- Graeme Spence
- Graham Cooke
- Hannah L. Bromley
- Hans Reitsma
- Hans Reitsma
- Hans Reitsma
- Harriet Hunt
- Harriet Hunt
- Henk C. P. M. van Weert
- Henrica de Vet
- Holly Smith
- Iain Marshall
- Ian Shrier
- Ijeoma Uchegbu
- Ijeoma Uchegbu
- Ijeoma Uchegbu
- Ijeoma Uchegbu
- Ioanna Tzoulaki
- Irene Rebollo-Mesa
- Isabel de Salis
- J. Ensor
- J. J. Deeks
- Jac Dinnes
- Jack O’Sullivan
- Jaime Peters
- Jaime Peters
- Jaime Peters
- Jaime Peters
- James A. Black
- James Buchanan
- James Buchanan
- James Thomas
- Jan Verbakel
- Janine Dretzke
- Jason Oke
- Javier Zamora
- Jen Murphy
- Jennifer Burr
- Jennifer Cooper
- Jennifer de Beyer
- Jennifer Murphy
- Jenny Donovan
- Jenny Hewison
- Jeremy Huddy
- Jeremy Huddy
- Jesse R. Fann
- Jessica Harris
- Jie Ma
- Jie Ma
- Joachim Marti
- Joanna Coast
- Johann de Bono
- Johanna A. A. G. Damen
- Johanna A. A. G. Damen
- Johanna A. A. G. Damen
- Johanna A. A. G. Damen
- Johanna Damen
- Johannes B. Reitsma
- Johannes B. Reitsma
- Johannes B. Reitsma
- Johannes B. Reitsma
- Johannes B. Reitsma
- Johannes Reitsma
- Johannes Reitsma
- Johannes Reitsma
- John Cairns
- John Dennis
- John Dennis
- John P. A. Ioannidis
- John Simpson
- Joie Ensor
- Jon Deeks
- Jon Deeks
- Jon Deeks
- Jon Deeks
- Jon Deeks
- Jon Deeks
- Jon Deeks
- Jonathan Cook
- Jonathan Cook
- Joris A. H. de Groot
- Joris de Groot
- Joris de Groot
- Joris de Groot
- Jos Kleinen
- Josée Zijlstra
- Joy Allen
- Joy Allen
- Joy Allen
- Judy Wright
- Judy Wright
- Julia R. Forman
- Julie Eatock
- Julie Parkes
- Julie Robotham
- Julien Asselineau
- Juwita Shaaban
- K. G. M. Moons
- Karel G. M. Moons
- Karel G. M. Moons
- Karel G. M. Moons
- Karel G. M. Moons
- Karel G. M. Moons
- Karel Moons
- Karel Moons
- Karel Moons
- Karel Moons
- Karel Moons
- Karel Moons
- Karen Moons
- Karen Vinall-Collier
- Karin A. Wittkampf
- Karoline Freeman
- Katharina Kramer
- Katherine Good
- Katie Banister
- Kevin Jenniskens
- Kinga Malottki
- Kurtis Lee
- Kym Snell
- Kym Snell
- Laure Wynants
- Laure Wynants
- Lavinia Ferrante di Ruffano
- Lavinia Ferrante Di Ruffano
- Lavinia Ferrante di Ruffano
- Lavinia Ferrante Di Ruffano
- Lesley Stafford
- Lieselotte Lennartz
- Linda M. Peelen
- Linda Peelen
- Linda Peelen
- Linda S. Williams
- Liz Mitchel
- Lorie A. Kloda
- Lotty Hooft
- Lotty Hooft
- Lotty Hooft
- Lotty Hooft
- Louise Johnson
- Louise Johnston
- Louise Johnston
- Lucinda Billingham
- Lucy Abel
- Lucy Abel
- M.Carmen Pardo
- Manjula Kumarasamy
- Manohursingh Rungall
- Manote Lotrakul
- Maria Dudareva
- Maria Hernandez-Fuentes
- Marie Westwood
- Mariska Leeflang
- Mariska Leeflang
- Mariska Leeflang
- Mark Gilchrist
- Martin Connock
- Martin Schumacher
- Mary A. Whooley
- Melody Ni
- Melody Ni
- Melody Ni
- Micael J. Pencina
- Michael Maia Schlüssel
- Michael Messenger
- Michael Messenger
- Michael Power
- Michael Power
- Michael Power
- Michelle Hutchinson
- Mie Holm-Vilstrup
- Mikyung Kelly Seo
- Miranda Langendam
- Nick Parsons
- Nicola Calder
- Nicola Calder
- Nirmala Rai
- null null
- null null
- null null
- null null
- null null
- null null
- null null
- Nuria Porta
- Nyantara Wickramasekera
- Obi Ukoumunne
- Oke Gerke
- Olga Tucker
- Oliver Kuss
- Otto Hoekstra
- Paramit Chowdhury
- Patrick Bossuyt
- Patrick Bossuyt
- Patrick Bossuyt
- Patrick Bossuyt
- Patrick Bossuyt
- Paul Perez
- Paula Mobillo
- Pauline Heus
- Pauline Heus
- Pauline Heus
- Pauline Heus
- Peggy Sekula
- Penny Whiting
- Penny Whiting
- Peter Hall
- Peter Hall
- Peter Phillips
- Peter Selby
- Peymane Adab
- Phillip Monaghan
- Pim Cuijpers
- Poul Flemming Høilund-Carlsen
- R. D. Riley
- Rachel Court
- Rachel Jordan
- Rachel O’Leary
- Rachel O’Leary
- Rachel O’Leary
- Rafael Perera
- Raphael Porcher
- Ray Waters
- Ray Waters
- Rebecca Albrow
- Rebecca Kift
- Richard Martin
- Richard Riley
- Richard Riley
- Rob J. P. M. Scholten
- Rob J. P. M. Scholten
- Rob J. P. M. Scholten
- Rob Scholten
- Robert Großelfinger
- Robert Wolff
- Rolf Groenwold
- Rolf Groenwold
- Romin Pajouheshnia
- Romin Pajouheshnia
- Romin Pajouheshnia
- Romin Pajouheshnia
- Romin Pajouheshnia
- Rosa Montero
- Roy C Ziegelstein
- Rupert Bourne
- Russell J. Steele
- Ruwanthi Kolamunnage-Dona
- Sabina Sanghera
- Sabine Van Huffel
- Sabine Van Huffel
- Sally Hopewell
- Sara Graziadio
- Sara Graziadio
- Sara Graziadio
- Sarah Byron
- Sarah Lord
- Scott B Patten
- Sian Taylor-Phillips
- Sian Taylor-Phillips
- Sian Taylor-Phillips
- Sian Taylor-Phillips
- Sibylle Sturtz
- Simon Gilbody
- Simon Stevens
- Simone Borsci
- Simone Borsci
- Simone Borsci
- Sofia Christakoudi
- Sonia R Loureiro
- Stephen Gerry
- Steve Halligan
- Steve Smith
- Steven Sacks
- Stuart A. Taylor
- Stuart A. Taylor
- Sudha Sundar
- Sue Bayliss
- Sue Mallet
- Sue Mallett
- Sue Mallett
- Sue Mallett
- Sue Mallett
- Sue Mallett
- Sue Mallett
- Sue Mallett
- Sue Mallett
- Sui Phin Kon
- Susan J. Dutton
- Susanne Steinhauser
- Sverre Sandberg
- Syed Mohiuddin
- Teresa Pérez
- Terry Strom
- Thomas Debray
- Thomas E. Nichols
- Thomas Fanshawe
- Thomas Fanshawe
- Thomas P. A. Debray
- Thomas P. A. Debray
- Thomas P. A. Debray
- Thomas R. Fanshawe
- Thomas R. Fanshawe
- Thomas Walker
- Tjir-Li Tsui
- Tom Nieto
- Tracy E. Roberts
- Trevor Cox
- Ulrich Halekoh
- Veerle Verheyden
- Virginia Chiocchia
- Walter Gregory
- Werner Vach
- Willi Sauerbrei
- Willi Sauerbrei
- William Henley
- William Henley
- William Rosenberg
- Wilma Verhagen-Kamerbeek
- Yaling Yang
- Yaling Yang
- Yannick Le Manach
- Yemisi Takwoingi
- Yvonne T. van der Schouw
- Yvonne Vergouwe
- Yvonne Vergouwe
- Zhivko Zhelev
- Zhivko Zhelev
- Zoe Plummer
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
Background: Evaluations of diagnostic tests are challenging because of the indirect nature of their impact on patient outcomes. Model-based health economic evaluations of tests allow different types of evidence from various sources to be incorporated and enable cost-effectiveness estimates to be made beyond the duration of available study data. To parameterize a health-economic model fully, all the ways a test impacts on patient health must be quantified, including but not limited to diagnostic test accuracy. Methods: We assessed all UK NIHR HTA reports published May 2009-July 2015. Reports were included if they evaluated a diagnostic test, included a model-based health economic evaluation and included a systematic review and meta-analysis of test accuracy. From each eligible report we extracted information on the following topics: 1) what evidence aside from test accuracy was searched for and synthesised, 2) which methods were used to synthesise test accuracy evidence and how did the results inform the economic model, 3) how/whether threshold effects were explored, 4) how the potential dependency between multiple tests in a pathway was accounted for, and 5) for evaluations of tests targeted at the primary care setting, how evidence from differing healthcare settings was incorporated. Results: The bivariate or HSROC model was implemented in 20/22 reports that met all inclusion criteria. Test accuracy data for health economic modelling was obtained from meta-analyses completely in four reports, partially in fourteen reports and not at all in four reports. Only 2/7 reports that used a quantitative test gave clear threshold recommendations. All 22 reports explored the effect of uncertainty in accuracy parameters but most of those that used multiple tests did not allow for dependence between test results. 7/22 tests were potentially suitable for primary care but the majority found limited evidence on test accuracy in primary care settings. Conclusions: The uptake of appropriate meta-analysis methods for synthesising evidence on diagnostic test accuracy in UK NIHR HTAs has improved in recent years. Future research should focus on other evidence requirements for cost-effectiveness assessment, threshold effects for quantitative tests and the impact of multiple diagnostic tests