Igneous Rock Associations 13. Focusing on the Central American Subduction Zone

Central America has recently been an important focus area for investigations into the complex processes occurring in subduction zones.  Here we review some of the new findings concerning subduction input, magma production and evolution, and resultant volcanic output.  In the Nicaraguan portion of the subduction zone, subduction input is unusually wet, likely caused by extensive serpentinization of the mantle portion of the incoming plate associated with bending-related faulting seaward of the Middle America trench. The atypical influx of water into the Nicaraguan section of the subduction zone ultimately leads to a regional maximum in the degree of mantle melting.  In central Costa Rica, subduction input is also unusual in that it includes oceanic crust flavored by the Galapagos plume.  Both of these exotic subduction inputs are recognizable in the compositions of magmas erupted along the volcanic front.  In addition, Nicaraguan magmas bear a strong chemical imprint from subducting hemipelagic sediments.  The high-field-strength-element depletions of magmas from El Salvador through Costa Rica are related to local variations in the depth to the subducting Cocos plate, and, therefore, to segmentation of the volcanic front.  Minor phases, probably amphibole or rutile, control these variable depletions. Silicic magmas erupted along the volcanic front exhibit the same along-arc geochemical variations as their mafic brethren.  This and their mantle-like radiogenic isotopic compositions suggest the production of juvenile continental crust all along the Central American subduction zone.  Punctuated times of enhanced magmatic input from the mantle may aid in crustal development.SOMMAIREL’Amérique centrale a récemment été le lieu de recherches sur les processus complexes se produisant dans les zones de subduction.  Ici nous passons en revue certaines découvertes sur nature des intrants de subduction, la production et l’évolution des magmas, ainsi que les extrants volcaniques résultants.  Dans le segment nicaraguayen de la zone de subduction, les intrants de subduction sont exceptionnellement humides, probablement à cause de la serpentinisation généralisée de la portion mantélique de la plaque en subduction, fissurée par flexure dans partie marine de la fosse océanique de l’Amérique centrale.  L'afflux atypique en eau dans le segment nicaraguayen de la zone de subduction induit ultimement un maximum régional de la proportion de fusion du manteau.  Dans la portion centrale du Costa Rica l’intrant de subduction est lui aussi atypique en ce qu’il comprend une croûte océanique teintée par le panache des Galápagos.  Ces deux intrants de subduction atypiques sont répercutés dans la composition des magmas éjectés le long du front volcanique.  En outre, les magmas nicaraguayens affichent une forte empreinte chimique héritée des sédiments hémipélagiques en subduction.  Les appauvrissements en éléments à fortes liaisons atomiques des magmas, du El Salvador jusqu’au Costa Rica, sont liés à des variations localisées de la profondeur de la plaque en subduction de Cocos, et donc, à la segmentation du front volcanique.  Des phases mineures, probablement amphibole et rutile, déterminent ces appauvrissements variables.  Les magmas siliceux éjectés le long du même front volcanique montrent les mêmes variations géochimiques le long de l’arc que leur contrepartie mafique.  De plus, les compositions radiogéniques de leurs contreparties mantéliques évoquent la production d’une croûte continentale juvénile le long de la zone de subduction de l’Amérique centrale.  Des épisodes d’accroissements ponctuels des intrants magmatiques du manteau peuvent contribuer au développement d’une croûte

Modeling and Comparing Vertical Density Profiles

The vertical density profile of pressed wood panels is influenced by the manufacturing process and is important to panel end-users. Modeling the vertical density profile and making statistical comparisons among profiles resulting from different manufacturing treatments are critical to understanding and improving panel properties. Nonparametric regression analysis was used to model the vertical density profile of aspen (Populus tremuloides) oriented strandboard panels. A methodology is presented to compare vertical density profile curves. Twenty-seven laboratory panels were manufactured at 608 kg/m3 incorporating three levels of furnish moisture content (4%, 8%, 12%) and three levels of press closure rate (20 s, 60 s, 100 s) in a replicated, experimental design.The nonparametric regression technique called cubic splines was used to fit the data, R2 ranged from 0.985 to 0.998. Detailed discussion is presented that describes the method and interpretation of the nonparametric regression analysis. Statistical comparison of vertical density profile curves among treatment levels revealed that the 4% furnish moisture content level was significantly different (P = 0.015) from the 8% and 12% levels; the 8% level was not significantly different (P > 0.99) from the 12% level. Vertical density profile curves for all press closure rate treatments were significantly different (P < 0.003)

Pulmonary hypertension: An important predictor of outcomes in patients undergoing non-cardiac surgery

SummaryObjectivesPerioperative risk associated with pulmonary hypertension (PH) in patients undergoing non-cardiac surgery (NCS) remains poorly defined. We report perioperative outcomes in a large cohort of patients undergoing NCS, comparing those with and without PH.MethodsPatients undergoing NCS at our institution between January 2002 and December 2006, were cross matched with a Right Heart Catheterization (RHC) database for the same period. Patients were excluded if they were <18 years old and if they underwent cardiac surgery prior to NCS or minor procedures using local anesthesia or sedation. Controls were defined as patients who underwent similar NCS with mean pulmonary arterial pressure (MPAP) ≤ 25 mmHg.Results173 patients underwent RHC and NCS during the specified period and were included in the analysis. Of these 96 (55%) had PH. Mean pulmonary arterial pressure (p = 0.001), American Association of Anesthesiology Class (p = 0.02), and chronic renal insufficiency (p = 0.03) were determined as independent risk factors for post-operative morbidity. Patients with PH were more likely to develop congestive heart failure (p < 0.001; OR: 11.9), hemodynamic instability (p < 0.002), sepsis (p < 0.0005), and respiratory failure (p < 0.004). Patients with PH needed longer ventilatory support (p < 0.002), stayed longer in the ICU (p < 0.04), and were more frequently readmitted to the hospital within 30 days (p < 008; OR 2.4).ConclusionsIn addition to the traditionally known risk factors for outcomes after NCS such as coronary artery disease, diabetes mellitus, chronic renal insufficiency, American Society of Anesthesiology class, the presence of underlying PH can have a significant negative impact on perioperative outcomes

Evaluation of Osteoconductive Scaffolds in the Canine Femoral Multi-Defect Model

Treatment of large segmental bone defects remains an unsolved clinical challenge, despite a wide array of existing bone graft materials. This project was designed to rapidly assess and compare promising biodegradable osteoconductive scaffolds for use in the systematic development of new bone regeneration methodologies that combine scaffolds, sources of osteogenic cells, and bioactive scaffold modifications. Promising biomaterials and scaffold fabrication methods were identified in laboratories at Rutgers, MIT, Integra Life Sciences, and Mayo Clinic. Scaffolds were fabricated from various materials, including poly(L-lactide-co-glycolide) (PLGA), poly(L-lactide-co-ɛ-caprolactone) (PLCL), tyrosine-derived polycarbonate (TyrPC), and poly(propylene fumarate) (PPF). Highly porous three-dimensional (3D) scaffolds were fabricated by 3D printing, laser stereolithography, or solvent casting followed by porogen leaching. The canine femoral multi-defect model was used to systematically compare scaffold performance and enable selection of the most promising substrate(s) on which to add cell sourcing options and bioactive surface modifications. Mineralized cancellous allograft (MCA) was used to provide a comparative reference to the current clinical standard for osteoconductive scaffolds. Percent bone volume within the defect was assessed 4 weeks after implantation using both MicroCT and limited histomorphometry. Bone formed at the periphery of all scaffolds with varying levels of radial ingrowth. MCA produced a rapid and advanced stage of bone formation and remodeling throughout the defect in 4 weeks, greatly exceeding the performance of all polymer scaffolds. Two scaffold constructs, TyrPC[subscript PL]/TCP and PPF4[subscript SLA]/HA[subscript PLGA Dip], proved to be significantly better than alternative PLGA and PLCL scaffolds, justifying further development. MCA remains the current standard for osteoconductive scaffolds.United States. Army Medical Research and Materiel Command (Armed Forces Institute of Regenerative Medicine)United States. Office of Naval ResearchUnited States. Air Force. Office of the Surgeon GeneralUnited States. NavyNational Institutes of Health (U.S.)United States. Veterans AdministrationCleveland Clinic Foundatio

CD98hc facilitates B cell proliferation and adaptive humoral immunity.

The proliferation of antigen-specific lymphocytes and resulting clonal expansion are essential for adaptive immunity. We report here that B cell-specific deletion of the heavy chain of CD98 (CD98hc) resulted in lower antibody responses due to total suppression of B cell proliferation and subsequent plasma cell formation. Deletion of CD98hc did not impair early B cell activation but did inhibit later activation of the mitogen-activated protein kinase Erk1/2 and downregulation of the cell cycle inhibitor p27. Reconstitution of CD98hc-deficient B cells with CD98hc mutants showed that the integrin-binding domain of CD98hc was required for B cell proliferation but that the amino acid-transport function of CD98hc was dispensable for this. Thus, CD98hc supports integrin-dependent rapid proliferation of B cells. We propose that the advantage of adaptive immunity favored the appearance of CD98hc in vertebrates

Investigation into the applicability of Bond Work Index (BWI) and Hardgrove Grindability Index (HGI) tests for several biomasses compared to Colombian La Loma coal

With increasing quantities of biomass being combusted in coal fired power stations, there is an urgent need to be able to predict the grindability of biomass in existing coal mills, but currently no standard biomass grindability test exists. In this study, the applicability of the Hardgrove Grindability Index (HGI) and Bond Work Index (BWI) as standard grindability tests for biomass were investigated for commercially sourced wood pellets, steam exploded pellets, torrefied pellets, sunflower pellets, eucalyptus pellets, miscanthus pellets, olive cake and Colombian La Loma coal. HGI predicts the behaviour of fuels in vertical spindle mills and BWI for tube and ball mills. Compared to La Loma (HGI of 46), all biomasses tested performed poorly with low HGI values (14–29). Miscanthus pellets had the highest BWI or Wi at 426 kW h/t. Despite similar HGI values, some untreated biomasses showed lower BWI values (Eucalyptus pellets Wi 87 kW h/t, HGI 22) compared to others (sunflower pellets Wi 366 kW h/t, HGI 20). Torrefied pellets had the lowest Wi (16 kW h/t), with La Loma coal at 23 kW h/t. Wood, miscanthus and sunflower pellets exhibited mill choking during the BWI test, as the amount of fines produced did not increase with an increasing revolution count. An approximate correlation between HGI and BWI was found for the biomass samples which did not experience mill choking in the BWI test. Milling results in this paper suggest that biomass pellets should be composed of pre-densified particles close to the target size in order to minimise the energy use in mills and possibility of mill choking. Our findings would also suggest that the BWI is a valid test for predicting the potential for mill choking of biomass in a tube and ball mill. HGI, however, appears to be a poor method of predicting the grindability of biomass in vertical spindle mills. A new standard grindability test is required to test the grindability of biomasses in such mills

Microlensing

Microlensing observations have now become a useful tool in searching for non--luminous astrophysical compact objects (brown dwarfs, faint stars, neutron stars, black holes and even planets). Originally conceived for establishing whether the halo of the Galaxy is composed of this type of objects, the ongoing searches are actually also sensitive to the dark constituents of other Galactic components (thin and thick disks, outer spheroid, bulge). We discuss here the present searches for microlensing of stars in the Magellanic Clouds and in the Galactic bulge (EROS, MACHO, OGLE and DUO collaborations). We analyse the information which can be obtained regarding the spatial distribution and motion of the lensing objects as well as about their mass function and their overall contribution to the mass of the Galaxy. We also discuss the additional signals, such as the parallax due to the motion of the Earth, the effects due to the finite source size and the lensing events involving binary objects, which can further constrain the lens properties. We describe the future prospects for these searches and the further proposed observations which could help to elucidate these issues, such as microlensing of stars in the Andromeda galaxy, satellite parallax measurements and infrared observations.Comment: Latex file, 59 p., 13 ps figures, to appear in Physics Reports (postcript file replaced by latex file

Bioavailability and extraction of heavy metals from contaminated soil by Atriplex halimus

Pot experiments were performed to evaluate the phytoremediation capacity of plants of Atriplex halimus grown in contaminated mine soils and to investigate the effects of organic amendments on the metal bioavailability and uptake of these metals by plants. Soil samples collected from abandoned mine sites north of Madrid (Spain) were mixed with 0, 30 and 60 Mg ha?1 of two organic amendments, with different pH and nutrients content: pine-bark compost and horse- and sheep-manure compost. The increasing soil organic matter content and pH by the application of manure amendment reduced metal bioavailability in soil stabilising them. The proportion of Cu in the most bioavailable fractions (sum of the water-soluble, exchangeable, acid-soluble and Fe?Mn oxides fractions) decreased with the addition of 60 Mg ha?1 of manure from 62% to 52% in one of the soils studied and from 50% to 30% in the other. This amendment also reduced Zn proportion in water-soluble and exchangeable fractions from 17% to 13% in one of the soils. Manure decreased metal concentrations in shoots of A. halimus, from 97 to 35 mg kg?1 of Cu, from 211 to 98 mg kg?1 of Zn and from 1.4 to 0.6 mg kg?1 of Cd. In these treatments there was a higher plant growth due to the lower metal toxicity and the improvement of nutrients content in soil. This higher growth resulted in a higher total metal accumulation in plant biomass and therefore in a greater amount of metals removed from soil, so manure could be useful for phytoextraction purposes. This amendment increased metal accumulation in shoots from 37 to 138 mg pot?1 of Cu, from 299 to 445 mg pot?1 of Zn and from 1.8 to 3.7 mg pot?1 of Cd. Pine bark amendment did not significantly alter metal availability and its uptake by plants. Plants of A. halimus managed to reduce total Zn concentration in one of the soils from 146 to 130 mg kg?1, but its phytoextraction capacity was insufficient to remediate contaminated soils in the short-to-medium term. However, A. halimus could be, in combination with manure amendment, appropriate for the phytostabilization of metals in mine soils

Phytostabilization of metals in mine soils using Brassica juncea in combination with organic amendments

Background and aims The high metal bioavailability and the poor conditions of mine soils yield a low plant biomass, limiting the application of phytoremediation techniques. A greenhouse experiment was performed to evaluate the effects of organic amendments on metal stabilization and the potential of Brassica juncea L. for phytostabilization in mine soils. Methods Plants were grown in pots filled with soils collected from two mine sites located in Central Spain mixed with 0, 30 and 60 tha?1 of pine bark compost and horse- and sheep-manure compost. Plant biomass and metal concentrations in roots and shoots were measured. Metal bioavailability was assessed using a rhizosphere-based method (rhizo), which consists of a mixture of low-molecular-weight organic acids to simulate root exudates. Results Manure reduced metal concentrations in shoots (10?50 % reduction of Cu and 40?80 % of Zn in comparison with non-amended soils), bioconcentration factor (10?50 % of Cu and 40?80 % of Zn) and metal bioavailability in soil (40?50 % of Cu and 10?30 % of Zn) due to the high pH and the contribution of organic matter. Manure improved soil fertility and was also able to increase plant biomass (5?20 times in shoots and 3?30 times in roots), which resulted in a greater amount of metals removed from soil and accumulated in roots (increase of 2?7 times of Cu and Zn). Plants grown in pine bark treatments and in non-amended soils showed a limited biomass and high metal concentrations in shoots. Conclusions The addition of manure could be effective for the stabilization of metals and for enhancing the phytostabilization ability of B. juncea in mine soils. In this study, this species resulted to be a potential candidate for phytostabilization in combination with manure, differing from previous results, in which B. juncea had been recognized as a phytoextraction plant