A fuzzy methodology for innovation management measurement

Innovation has been recognized as one of the main sources of competitive advantage for organizations and nations. The purpose of this study is to present an innovation management measurement approach applying fuzzy techniques to small and medium manufacturing enterprises. ..

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

Centrality evolution of the charged-particle pseudorapidity density over a broad pseudorapidity range in Pb-Pb collisions at root s(NN)=2.76TeV

Peer reviewe

NNOVACIÓN EN CLUSTERS TURÍSTICOS: UNA APROXIMACIÓN DESDE LA LÓGICA DIFUSA Y LA TEORÍA DE GRUPOS DE GALOIS

El turismo desempeña un papel decisivo en el desarrollo de ciudades y regiones, sin embargo, la competencia entre destinos turísticos, la globalización y tendencias cambiantes producen desafíos a tomadores de decisión y ceadores de políticas. Se propone una estructura metodológica para la agrupación de puntos de interés de la ciudad de Morelia, Michoacán — México utilizando la Teoría de Grupos de Galois y Lógica Difusa. Resultados concluyen que productos con diferentes características se pueden agrupar bajo una técnica estructurada y visual. La originalidad del estudio se basa en la flexibilidad del modelo para agrupar diferentes lugares bajo condiciones subjetivas e inciertas

Heart Rate and Mortality in Patients With Acute Symptomatic Pulmonary Embolism

International audienc

Measurement of K*(892)(+/-) production in inelastic pp collisions at the LHC

The first results on K⁎(892)± resonance production in inelastic pp collisions at LHC energies of s=5.02, 8, and 13 TeV are presented. The K⁎(892)± has been reconstructed via its hadronic decay channel K⁎(892)→±KS0+π± with the ALICE detector. Measurements of transverse momentum distributions, pT-integrated yields, and mean transverse momenta for charged K⁎(892) are found to be consistent with previous ALICE measurements for neutral K⁎(892) within uncertainties. For pT>1 GeV/c the K⁎(892)± transverse momentum spectra become harder with increasing centre-of-mass energy from 5.02 to 13 TeV, similar to what previously observed for charged kaons and pions. For pT<1 GeV/c the K⁎(892)± yield does not evolve significantly and the abundance of K⁎(892)± relative to K is rather independent of the collision energy. The transverse momentum spectra, measured for K⁎(892)± at midrapidity in the interval 0 < pT<15 GeV/c, are not well described by predictions of different versions of PYTHIA 6, PYTHIA 8 and EPOS-LHC event generators. These generators reproduce the measured pT-integrated K⁎±/K ratios and describe well the momentum dependence for pT<2 GeV/c

KS0KS0 and KS0K± femtoscopy in pp collisions at √s=5.02 and 13 TeV

Femtoscopic correlations with the particle pair combinations K0 SK0 S and K0 SK± are studied in pp collisions at √s = 5.02 and 13 TeV by the ALICE experiment. At both energies, boson source parameters are extracted for both pair combinations, by fitting models based on Gaussian size distributions of the sources, to the measured two-particle correlation functions. The interaction model used for the K0 SK0 S analysis includes quantum statistics and strong final-state interactions through the f0(980) and a0(980) resonances. The model used for the K0 SK± analysis includes only the final-state interaction through the a0 resonance. Source parameters extracted in the present work are compared with published values from pp collisions at √s = 7 TeV and the different pair combinations are found to be consistent. From the observation that the strength of the K0 SK0 S correlations is significantly greater than the strength of the K0 SK± correlations, the new results are compatible with the a0 resonance being a tetraquark state of the form (q1, q2, s, s), where q1 and q2 are u or d quarks

Coherent J/psi photoproduction at forward rapidity in ultra-peripheral Pb-Pb collisions at root s(NN)=5.02 TeV

The ALICE collaboration performed the first rapidity-differential measurement of J/psi coherent photoproduction in ultra-peripheral Pb\u2013Pb collisions at a center-of-mass energy sqrt(sNN) = 5.02 TeV. The J/psi is detected via its dimuon decay in the forward rapidity region (-4.0 < y < -2.5) for events where the hadronic activity is required to be minimal. The analysis is based on an event sample corresponding to an integrated luminosity of about 750 \u3bcb 121. The cross section for J/psi coherent production is presented in six rapidity bins. The results are compared with theoretical models for J/psi coherent photoproduction. These comparisons indicate that gluon shadowing effects play a role in the photoproduction process. The ratio of psi' to J/psi coherent photoproduction cross sections was measured and found to be consistent with that measured for photoproduction off protons