Debt-for-Nature Swaps : transnational environmental politics in a changing global political economy or NGOs, LDCs and IOUs

Debt-for-nature swaps are a new phenomenon in world politics. Initiated as a response to third world debt problems and the urgent need for environmental protection, debt-for-nature swaps represent a very interesting development in the areas of international finance, international negotiation and international roles for non-state actors. To date, at least nineteen swaps have taken place, and according to some observers, they fit a niche that will exist for some time to come

The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: a collaborative analysis of ten large cohort studies

Peer reviewe

New genetic loci link adipose and insulin biology to body fat distribution.

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms

Officieren van Justitie in de fout

Door fouten van officieren van Justitie komen regelmatig verdachten van ernstige misdaden vrij of verdwijnen soms onschuldige mensen voor jaren achter de tralies. We onderzochten hoeveel zaken de afgelopen jaren fout zijn gegaan. En worden falende officieren wel gestraft? Of gaan ze gewoon door met hun carrière en maken ze later promotie?

Additional file 3: Table S2. of Safety, tolerability and pharmacodynamics of apical sodium-dependent bile acid transporter inhibition with volixibat in healthy adults and patients with type 2 diabetes mellitus: a randomised placebo-controlled trial

Glucose–insulin metabolism pharmacodynamic parameters in patients with type 2 diabetes mellitus. (DOCX 43 kb